Geert Berx
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Biology
Geert Berx's Degrees
- PhD Biomedical Sciences University of Antwerp
- Bachelors Biology University of Antwerp
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(Suggest an Edit or Addition)Geert Berx's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulatory networks defining EMT during cancer initiation and progression (2013) (2181)
- The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. (2001) (1396)
- The cell-cell adhesion molecule E-cadherin (2008) (1109)
- E‐cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. (1995) (807)
- Guidelines and definitions for research on epithelial–mesenchymal transition (2020) (778)
- DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells (2005) (742)
- EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research (2017) (699)
- Involvement of members of the cadherin superfamily in cancer. (2009) (645)
- Mutations of the human E‐cadherin (CDH1) gene (1998) (610)
- SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell–cell junctions (2005) (556)
- The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression (2001) (472)
- E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. (1996) (471)
- A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. (2006) (460)
- A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment (2019) (446)
- The role of the ZEB family of transcription factors in development and disease (2009) (422)
- E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis. (1997) (349)
- Simultaneous loss of E‐cadherin and catenins in invasive lobular breast cancer and lobular carcinoma in situ (1997) (304)
- Cadherins and epithelial-to-mesenchymal transition. (2013) (299)
- E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma (2001) (282)
- VHL Promotes E2 Box-Dependent E-Cadherin Transcription by HIF-Mediated Regulation of SIP1 and Snail (2006) (264)
- Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. (2016) (264)
- Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer (2007) (249)
- Snail promotes Wnt target gene expression and interacts with β-catenin (2008) (244)
- Unraveling signalling cascades for the Snail family of transcription factors. (2005) (234)
- Molecular and pathological signatures of epithelial–mesenchymal transitions at the cancer invasion front (2008) (227)
- Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1). (1995) (222)
- The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. (2005) (214)
- The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer. (1999) (207)
- Modulation of iron transport proteins in human colorectal carcinogenesis (2006) (206)
- EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET. (2017) (196)
- Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. (2007) (195)
- Regulation of vimentin by SIP1 in human epithelial breast tumor cells (2006) (187)
- Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells. (1995) (184)
- E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas. (1999) (182)
- Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity. (2017) (175)
- Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression (2014) (169)
- Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research (2017) (147)
- The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages (2018) (138)
- Evolutionary functional analysis and molecular regulation of the ZEB transcription factors (2012) (133)
- Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection (2015) (126)
- The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance (2019) (119)
- Directed Migration of Cortical Interneurons Depends on the Cell-Autonomous Action of Sip1 (2013) (117)
- Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas. (1998) (111)
- Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes. (2009) (110)
- Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells (2009) (106)
- E‐cadherin gene alterations are rare events in thyroid tumors (1997) (102)
- The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2 (2016) (101)
- Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression (2010) (97)
- Genomic organization of the human beta-catenin gene (CTNNB1). (1996) (97)
- The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. (2011) (95)
- Strategies for immortalization of primary hepatocytes. (2014) (83)
- Concepts of metastasis in flux: the stromal progression model. (2012) (83)
- Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes. (2017) (83)
- Cadherin/catenin complex: A target for antiinvasive therapy? (1996) (73)
- ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling (2015) (69)
- Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity (2014) (68)
- Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells. (2016) (67)
- The MCM-Binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair (2010) (65)
- Module Network Inference from a Cancer Gene Expression Data Set Identifies MicroRNA Regulated Modules (2010) (64)
- Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells (2002) (63)
- GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3. (2004) (61)
- Identification of excretory-secretory products of larval and adult Ostertagia ostertagi by immunoscreening of cDNA libraries. (2003) (60)
- From neural crest cells to melanocytes: cellular plasticity during development and beyond (2019) (59)
- USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia (2018) (59)
- A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes (2008) (56)
- Distinct deleted regions on chromosome segment 16q23–24 associated with metastases in prostate cancer (1999) (56)
- Program through Modulation of the Epithelial Cell Differentiation The Transcription Factor Snail Induces Tumor Cell Invasion (2005) (48)
- Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma. (2010) (48)
- Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia (2017) (48)
- Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium (2015) (47)
- Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential (2013) (45)
- Nanos genes and their role in development and beyond (2018) (44)
- Proteolytic cleavage of β‐catenin by caspases: an in vitro analysis (1999) (42)
- Epithelial-Mesenchymal Transition (EMT) as a Therapeutic Target (2021) (40)
- Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells (2016) (38)
- E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion. (2006) (38)
- Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization. (1995) (38)
- Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. (2008) (37)
- The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression (2008) (36)
- NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest (2015) (35)
- Expression of the E‐cadherin–catenin complex in lung neuroendocrine tumours (2001) (34)
- A novel RIPK4–IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes (2014) (34)
- The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype (2020) (34)
- Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells. (2015) (33)
- Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis. (1999) (32)
- Identification of eleven novel tumor‐associated e‐cadherin mutations (1999) (32)
- Cadherins in cancer. (2004) (32)
- Gene expression profiling to dissect the complexity of cancer biology: pitfalls and promise. (2012) (29)
- Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons (2004) (29)
- Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection (2020) (27)
- p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification (2016) (26)
- Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo. (2018) (26)
- ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins (2014) (24)
- The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1. (2020) (24)
- An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation (2018) (24)
- Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25‐kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients (2002) (23)
- Snail in the frame of malignant tumor recurrence (2006) (23)
- Zeb2 drives invasive and microbiota-dependent colon carcinoma (2020) (22)
- Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression. (2013) (21)
- Isolation and characterization of a human pseudogene (CTNNAP1) for alpha E-catenin (CTNNA1): assignment of the pseudogene to 5q22 and the alpha E-catenin gene to 5q31. (1995) (21)
- Identification of potential protective antigens of Ostertagia ostertagi with local antibody probes (2002) (18)
- Intrinsic Balance between ZEB Family Members Is Important for Melanocyte Homeostasis and Melanoma Progression (2020) (17)
- Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation. (2017) (17)
- Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia. (2016) (16)
- LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19 (2016) (16)
- ZEB Proteins in Leukemia: Friends, Foes, or Friendly Foes? (2018) (16)
- An efficient and reliable multiplex PCR‐SSCP mutation analysis test applied to the human E‐cadherin gene (1997) (16)
- Deregulation of the Replisome Factor MCMBP Prompts Oncogenesis in Colorectal Carcinomas through Chromosomal Instability12 (2014) (15)
- ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition (2018) (15)
- Protein disulphide isomerase of Ostertagia ostertagi: an excretory-secretory product of L4 and adult worms? (2003) (15)
- ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms (2018) (14)
- Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma (2019) (13)
- The role of E-cadherin in epithelial differentiation and cancer progression (2003) (12)
- Identification of putative cancer genes through data integration and comparative genomics between plants and humans (2012) (12)
- Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1 (2022) (11)
- Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study (2019) (11)
- The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer (2021) (11)
- XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells (2021) (11)
- Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice (2018) (10)
- Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis (2021) (10)
- The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma (2021) (9)
- Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice (2021) (9)
- Genetic characterization and therapeutic targeting of MYC‐rearranged T cell acute lymphoblastic leukaemia (2018) (8)
- Xenogen-free isolation and culture of human adipose mesenchymal stem cells. (2019) (8)
- Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity (2021) (7)
- Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells (2003) (7)
- Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition (2021) (7)
- Partial EMT takes the lead in cancer metastasis. (2021) (7)
- ZEB2 in T-cells and T-ALL. (2019) (6)
- Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair (2009) (6)
- The Invasion Suppressor Role of E-Cadherin (1992) (6)
- Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state (2022) (5)
- Ileal immune tonus is a prognosis marker of proximal colon cancer in mice and patients (2020) (5)
- Allelic imbalance at the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types. (1997) (5)
- Development and characterization of a new human hepatic cell line (2015) (5)
- Epithelial Cell Plasticity by Dynamic Transcriptional Regulation of E-Cadherin (2005) (5)
- Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies (2019) (5)
- Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange. (2017) (4)
- E-cadherin controlling epithelial differentiation in human carcinomas (2001) (3)
- Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells (2021) (2)
- The EMT Modulator SNAI1 Drives AML Development Via Its Interaction with the Chromatin Modulator LSD1 (2016) (2)
- Allelic imbalance of the beta-catenin gene (CTNNB1 at 3p22-21.3) in various human tumor types (vol 11, pg 311, 1997) (1998) (2)
- Evolutionary functional analysis and molecular regulation of the ZEB transcription factors (2012) (2)
- A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the the human NBPF1 and ACCN1 genes (2008) (2)
- Targeting BET family proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia (2016) (1)
- Integration of suppression subtractive hybridization, laser capture microdissection and microarray analysis for identification of genes implicated in neuroblastoma pathogenesis (2001) (1)
- Guidelines and definitions for research on epithelial–mesenchymal transition (2020) (1)
- hematopoietic stem/progenitor cell differentiation and mobilization The EMT regulator Zeb2/Sip1 is essential for murine embryonic (2012) (1)
- Distinct transcriptional programs in ascitic and solid cancer cells induce different responses to chemotherapy in high-grade serous ovarian cancer. (2022) (1)
- Abberations in E-cadherin in lobular breast cancer (1996) (1)
- Nanos genes and their role in development and beyond (2018) (1)
- A new mouse model to study the role of ectopic Nanos3 expression in cancer (2019) (1)
- Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research (2017) (1)
- A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer. (2023) (1)
- Neuroblastoma: from molecular cytogenetics to gene expression profiling (1999) (1)
- Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma (2020) (0)
- ’ s response to reviews Title : A new mouse model to study the role of ectopic Nanos 3 expression in cancer (2019) (0)
- A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment (2019) (0)
- NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest (2015) (0)
- Defining the composition of Ostertagia ostertagi excretory-secretory products (2002) (0)
- THE BELGIAN SOCIETY FOR CELL BIOLOGYBELGIAN CELL BIOLOGY. TOWARDS THE 21st CENTURY. SILVER JUBILEE MEETING (1998) (0)
- EMT transcription factors induce tissue factor expression and pro-coagulant properties, supporting early metastasis of circulating tumor cells (2017) (0)
- ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins (2014) (0)
- Abstract B39: BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia (2016) (0)
- Abstract A08: Fast and efficient generation of conditional ROSA26-based mouse models that recapitulate oncogene activation in T-cell acute lymphoblastic leukemia (2018) (0)
- Evaluation of SSH for identification of differential expressed genes in neuroblastoma (2000) (0)
- Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells (2021) (0)
- A new mouse model to study the role of ectopic Nanos3 expression in cancer (2019) (0)
- Viewpoint Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex (2009) (0)
- A process for the control of tumor progression and invasiveness (2003) (0)
- The combination of ABT-199 and JQ1 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia (2016) (0)
- E-cadherin versus tumor invasion (1993) (0)
- ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition (2018) (0)
- THE EMT INDUCER SIP1/ZEB2 IS ESSENTIAL FOR DEFINITIVE EMBRYONIC HEMATOPOIESIS (2010) (0)
- Publisher Correction: Zeb2 drives invasive and microbiota-dependent colon carcinoma (2020) (0)
- 2008 - ALTERED EXPRESSION OF EPITHELIAL TO MESENCHYMAL TRANSITION MODULATORS IN ACUTE MYELOID LEUKAEMIA - A MODEL OF LSD1 CORRUPTION (2019) (0)
- Abstract B25: BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia (2016) (0)
- TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia (2018) (0)
- Abstract B21: Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia (2016) (0)
- Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies (2019) (0)
- Identification of putative cancer genes through data integration and comparative genomics between plants and humans (2012) (0)
- Cyclin D2 Overexpression Recapitulates Mantle Cell Lymphoma in Mice (2016) (0)
- BRD4 inhibition improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia (2016) (0)
- FOS-Related Antigen 1 (FRA-1) Switches Breast Cancer Cells from a Luminal to a Basal-like Subtype with Spontaneous Metastasis Behavior (2012) (0)
- Abstract LB-147: EMT transcription factors induce tissue factor expression and pro-coagulant properties, supporting early metastasis of circulating tumor cells (2017) (0)
- Fast generation of conditional ROSA26-based mouse models that recapitulate genomic events in human T-ALL (2016) (0)
- Abstract B151: Epithelial‐to‐mesenchymal transition (EMT) in resistance to the antiproliferative effects of elisidepsin (Irvalec™), a novel marine‐derived depsipeptide, in colon cancer cells (2009) (0)
- Identification of differentially expressed genes in neuroblastoma (2000) (0)
- Novel tools for dissecting the functions of Kupffer cells in homeostasis and disease reveal a role for the transcription factors Zeb2 and LXRa in maintaining Kupffer cell identity (2018) (0)
- Targeting BET family proteins improves the efficacy of ABT-199 in T-cell acute lymphoblastic leukemia (2016) (0)
- From neural crest cells to melanocytes: cellular plasticity during development and beyond (2019) (0)
- Tumor engineering a clinical relevant model that recapitulates the tumor environment of peritoneal metastases in vitro and in vivo (2019) (0)
- Table of Contents (1995) (0)
- MLKL deficiency in BrafV600EPten−/− melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice (2022) (0)
- Cell Adhesion and Cell Polarity in Development and Disease (2012) (0)
- Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice (2018) (0)
- Genetic analysis of neuroblastoma : differential transcripts lead the way (2000) (0)
- Child Puberty Adult metastasis EMT MET Snail 2 ? Twist 1 Snail 1 (0)
- In vivo visualisation of vessel formation in peritoneal tumour scaffolds with μCT (2017) (0)
- Myb drives B-cell neoplasms and myeloid malignancies in vivo (2022) (0)
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What Schools Are Affiliated With Geert Berx?
Geert Berx is affiliated with the following schools:
