Genji Imokawa
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Computer Science
Genji Imokawa's Degrees
- PhD Computer Science Imperial University of Japan
- Masters Computer Science Imperial University of Japan
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(Suggest an Edit or Addition)Genji Imokawa's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Decreased level of ceramides in stratum corneum of atopic dermatitis: an etiologic factor in atopic dry skin? (1991) (969)
- Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis. (1994) (454)
- Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. (1992) (365)
- Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders. (2004) (342)
- Age‐related changes in the elastic properties and thickness of human facial skin (1994) (287)
- Effects of endothelins on signal transduction and proliferation in human melanocytes. (1991) (249)
- Endothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis. (1995) (234)
- Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus. (2002) (224)
- High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis. (2000) (221)
- Stratum corneum lipids serve as a bound-water modulator. (1990) (212)
- Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency? (1996) (211)
- Selective recovery of deranged water-holding properties by stratum corneum lipids. (1986) (205)
- The paracrine role of stem cell factor/c-kit signaling in the activation of human melanocytes in ultraviolet-B-induced pigmentation. (2001) (189)
- The Role of Elastases Secreted by Fibroblasts in Wrinkle Formation: Implication Through Selective Inhibition of Elastase Activity¶ (2001) (185)
- Importance of intercellular lipids in water-retention properties of the stratum corneum: induction and recovery study of surfactant dry skin (2004) (183)
- A possible function of structural lipids in the water-holding properties of the stratum corneum. (1985) (173)
- Modulation of melanogenic protein expression during the switch from eu- to pheomelanogenesis. (1995) (172)
- Tyrosinase Stabilization by Tyrp1 (the brown Locus Protein)* (1998) (171)
- The role of endothelin-1 in epidermal hyperpigmentation and signaling mechanisms of mitogenesis and melanogenesis. (1997) (163)
- Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes. (1996) (158)
- Percutaneous sensitization with allergens through barrier‐disrupted skin elicits a Th2‐dominant cytokine response (1998) (145)
- The role of the epidermal endothelin cascade in the hyperpigmentation mechanism of lentigo senilis. (2001) (130)
- Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide β-1,4-Galactosyltransferase from Rat Brain* (1998) (129)
- The Pmel 17/silver locus protein. Characterization and investigation of its melanogenic function. (1994) (126)
- Granulocyte/macrophage colony-stimulating factor is an intrinsic keratinocyte-derived growth factor for human melanocytes in UVA-induced melanosis. (1996) (125)
- Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. (2010) (125)
- Mechanisms underlying the dysfunction of melanocytes in vitiligo epidermis: role of SCF/KIT protein interactions and the downstream effector, MITF‐M (2004) (119)
- Age‐related changes in skin wrinkles assessed by a novel three‐dimensional morphometric analysis (2002) (118)
- Deficient Production of Hexadecenoic Acid in the Skin Is Associated in Part with the Vulnerability of Atopic Dermatitis Patients to Colonization by Staphylococcus aureus (2005) (112)
- Intracellular Signaling Mechanisms Leading to Synergistic Effects of Endothelin-1 and Stem Cell Factor on Proliferation of Cultured Human Melanocytes (2000) (111)
- Analysis of beta-glucocerebrosidase and ceramidase activities in atopic and aged dry skin. (1994) (107)
- The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation. (2004) (105)
- Molecular analysis of elastic properties of the stratum corneum by solid-state 13C-nuclear magnetic resonance spectroscopy. (1995) (104)
- Loss of melanogenic properties in tyrosinases induced by glucosylation inhibitors within malignant melanoma cells. (1982) (101)
- Biological Mechanisms Underlying the Ultraviolet Radiation-Induced Formation of Skin Wrinkling and Sagging I: Reduced Skin Elasticity, Highly Associated with Enhanced Dermal Elastase Activity, Triggers Wrinkling and Sagging (2015) (100)
- Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. (2004) (97)
- Modulation of murine melanocyte function in vitro by agouti signal protein (1997) (97)
- Biological characterization of human fibroblast-derived mitogenic factors for human melanocytes. (1998) (96)
- Altered permeability and disordered cutaneous immunoregulatory function in mice with acute barrier disruption. (1997) (95)
- Epistatic connections between microphthalmia‐associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders (2008) (94)
- Lipid abnormalities in atopic dermatitis. (2001) (89)
- Quantitative Analysis of Stratum Corneum Lipids in Xerosis and Asteatotic Eczema (1993) (85)
- Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: an implication for the disrupted barrier mechanism in atopic dermatitis. (2012) (82)
- Recent advances in characterizing biological mechanisms underlying UV-induced wrinkles: a pivotal role of fibrobrast-derived elastase (2008) (80)
- The skin of atopic dermatitis patients contains a novel enzyme, glucosylceramide sphingomyelin deacylase, which cleaves the N-acyl linkage of sphingomyelin and glucosylceramide. (2000) (79)
- Selective inhibition of skin fibroblast elastase elicits a concentration-dependent prevention of ultraviolet B-induced wrinkle formation. (2001) (79)
- Study on skin roughness caused by surfactants: II. Correlation between protein denaturation and skin roughness (1975) (77)
- A possible mechanism underlying the ceramide deficiency in atopic dermatitis: expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide. (2009) (77)
- Inhibition of ultraviolet‐B‐induced wrinkle formation by an elastase‐inhibiting herbal extract: implication for the mechanism underlying elastase‐associated wrinkles (2005) (77)
- Selective aberration and pigment loss in melanosomes of malignant melanoma cells in vitro by glycosylation inhibitors: premelanosomes as glycoprotein. (1983) (75)
- Mechanism of UVB-induced wrinkling of the skin: paracrine cytokine linkage between keratinocytes and fibroblasts leading to the stimulation of elastase. (2009) (70)
- Comparison of skin barrier function and sensory nerve electric current perception threshold between IgE‐high extrinsic and IgE‐normal intrinsic types of atopic dermatitis (2010) (70)
- Pseudo-acylceramide with linoleic acid produces selective recovery of diminished cutaneous barrier function in essential fatty acid-deficient rats and has an inhibitory effect on epidermal hyperplasia. (1994) (69)
- Purification and Biochemical Characterization of Membrane-bound Epidermal Ceramidases from Guinea Pig Skin (*) (1995) (67)
- The mechanism of epidermal hyperpigmentation in café‐au‐lait macules of neurofibromatosis type 1 (von Recklinghausen's disease) may be associated with dermal fibroblast‐derived stem cell factor and hepatocyte growth factor (2003) (58)
- The mechanism of epidermal hyperpigmentation in dermatofibroma is associated with stem cell factor and hepatocyte growth factor expression. (2001) (58)
- Degree of ultraviolet-induced tortuosity of elastic fibers in rat skin is age dependent. (1995) (57)
- Analysis of initial melanogenesis including tyrosinase transfer and melanosome differentiation through interrupted melanization by glutathione. (1989) (57)
- Characterization of the lipid composition at the proximal root regions of human hair. (2005) (55)
- DHICA oxidase activity of TRP1 and interactions with other melanogenic enzymes. (1994) (55)
- Dermal fluid translocation is an important determinant of the diurnal variation in human skin thickness (2001) (55)
- Ovariectomy is sufficient to accelerate spontaneous skin ageing and to stimulate ultraviolet irradiation‐induced photoageing of murine skin (2004) (53)
- Astaxanthin attenuates the UVB‐induced secretion of prostaglandin E2 and interleukin‐8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion–independent manner (2012) (53)
- Sphingosylphosphorylcholine is a potent inducer of intercellular adhesion molecule-1 expression in human keratinocytes. (1999) (52)
- Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis Published, JLR Papers in Press, October 1, 2002. DOI 10.1194/jlr.M200225-JLR200 (2003) (52)
- Decreased levels of covalently bound ceramide are associated with ultraviolet B-induced perturbation of the skin barrier. (2004) (51)
- Assessment of Epidermal Barrier Function by Photoacoustic Spectrometry in Relation to Its Importance in the Pathogenesis of Atopic Dermatitis (2002) (51)
- Neprilysin Is Identical to Skin Fibroblast Elastase (2010) (49)
- A photographic scale for the assessment of human facial wrinkles (2000) (48)
- Abnormal Expression of the Novel Epidermal Enzyme, Glucosylceramide Deacylase, and the Accumulation of its Enzymatic Reaction Product, Glucosylsphingosine, in the Skin of Patients with Atopic Dermatitis (2003) (47)
- Inhibitors of Intracellular Signaling Pathways that Lead to Stimulated Epidermal Pigmentation: Perspective of Anti-Pigmenting Agents (2014) (46)
- Functional analysis of tyrosinase isozymes of cultured malignant melanoma cells during the recovery period following interrupted melanogenesis induced by glycosylation inhibitors. (1984) (45)
- Cumulative effect of surfactants on cutaneous horny layers: Adsorption onto human keratin layers in vivo (1979) (44)
- Differential analysis of experimental hypermelanosis induced by UVB, PUVA, and allergic contact dermatitis using a brownish guinea pig model (2004) (43)
- Microanalysis of an antimicrobial peptide, β‐defensin‐2, in the stratum corneum from patients with atopic dermatitis (2008) (43)
- Biological Mechanisms Underlying the Ultraviolet Radiation-Induced Formation of Skin Wrinkling and Sagging II: Over-Expression of Neprilysin Plays an Essential Role (2015) (43)
- Ultraviolet-B irradiation deforms the configuration of elastic fibers during the induction of actinic elastosis in rats. (1994) (41)
- A single UVB exposure increases the expression of functional KIT in human melanocytes by up-regulating MITF expression through the phosphorylation of p38/CREB (2010) (41)
- Role of endothelin‐1 in hyperpigmentation in seborrhoeic keratosis (1996) (40)
- A systematic method for the sensitive and specific determination of hair lipids in combination with chromatography. (2005) (40)
- Water-retaiming function in the stratum corneum and its recovery properties by synthetic pseudoceramides (1989) (38)
- Role of Ceramide in the Barrier Function of the Stratum Corneum, Implications for the Pathogenesis of Atopic Dermatitis (2014) (38)
- The Effects of UVA and UVB Irradiation on the Viscoelastic Properties of Hairless Mouse Skin in vivo (1998) (37)
- Surface activity and cutaneous effects of monoalkyl phosphate surfactants (1978) (37)
- Sphingosylphosphorylcholine is an activator of transglutaminase activity in human keratinocytes. (2001) (35)
- Comparative study on the mechanism of irritation by sulfate and phosphate type of anionic surfactants (1980) (35)
- Study on skin roughness caused by surfactants: I. A new method in vivo for evaluation of skin roughness (1975) (34)
- Analysis of tyrosinases as asparagin-linked oligosaccharides by concanavalin A lectin chromatography: appearance of new segment of tyrosinases in melanoma cells following interrupted melanogenesis induced by glycosylation inhibitors. (1985) (34)
- The induction of skin tightness by surfactants (1984) (33)
- Skin organ culture model for examining epidermal melanization. (1993) (32)
- Importance of glycoproteins in the initiation of melanogenesis: an electron microscopic study of B-16 melanoma cells after release from inhibition of glycosylation. (1986) (31)
- Characterization of Surfactant-Induced Skin Damage through Barrier Recovery Induced by Pseudoacylceramides (2005) (31)
- UVB Stimulates the Expression of Endothelin B Receptor in Human Melanocytes via a Sequential Activation of the p38/MSK1/CREB/MITF Pathway Which Can Be Interrupted by a French Maritime Pine Bark Extract through a Direct Inactivation of MSK1 (2015) (30)
- An accumulation of glucosylceramide in the stratum corneum due to attenuated activity of beta-glucocerebrosidase is associated with the early phase of UVB-induced alteration in cutaneous barrier function (2005) (30)
- Age-Related Alterations of Echogenicity in Japanese Skin (2000) (30)
- Surfactant-Induced Depletion of Ceramides and Other Intercellular Lipids: Implication for the Mechanism Leading to Dehydration of the Stratum corneum (2005) (29)
- Sphingosylphosphorylcholine is a Melanogenic Stimulator for Human Melanocytes. (2003) (28)
- Unusual wrinkle formation after temporary skin fixation followed by UVB irradiation in hairless mouse skin (1996) (28)
- Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005. (2006) (27)
- New inhibitors of melanogenesis, OH-3984 K1 and K2. I. Taxonomy, fermentation, isolation and biological characteristics. (1993) (26)
- The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFκBp65 Ser276 Axis (2015) (25)
- Reevaluation of the non-lesional dry skin in atopic dermatitis by acute barrier disruption: an abnormal permeability barrier homeostasis with defective processing to generate ceramide (2014) (25)
- Biosynthesis of acylceramide in murine epidermis: characterization by inhibition of glucosylation and deglucosylation, and by substrate specificity. (2004) (24)
- A possible role of prostaglandins in PUVA-induced inflammation: implication by organ cultured skin. (1989) (24)
- Functions of lipids on human skin (1989) (24)
- Biochemical characterization of tyrosinase inhibitors using tyrosinase binding affinity chromatography (1981) (24)
- Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes (2012) (23)
- Abrogating effect of a xanthophyll carotenoid astaxanthin on the stem cell factor-induced stimulation of human epidermal pigmentation (2012) (23)
- Epithelial-mesenchymal interaction during UVB-induced up-regulation of neutral endopeptidase. (2012) (23)
- Crucial role of fibroblast integrins α2 and β1 in maintaining the structural and mechanical properties of the skin (2007) (23)
- An extract of Melia toosendan attenuates endothelin-1-stimulated pigmentation in human epidermal equivalents through the interruption of PKC activity within melanocytes (2011) (22)
- Differential hypermelanosis induced by allergic contact dermatitis. (1987) (21)
- The stem cell factor-stimulated melanogenesis in human melanocytes can be abrogated by interrupting the phosphorylation of MSK1: evidence for involvement of the p38/MSK1/CREB/MITF axis (2018) (21)
- Epidermal change can alter mechanical properties of hairless mouse skin topically treated with 1alpha, 25-dihydroxyvitamin D(3). (2000) (21)
- Astaxanthin and withaferin A block paracrine cytokine interactions between UVB-exposed human keratinocytes and human melanocytes via the attenuation of endothelin-1 secretion and its downstream intracellular signaling. (2015) (20)
- Reevaluation of the Importance of Barrier Dysfunction in the Nonlesional Dry Skin of Atopic Dermatitis Patients through the Use of Two Barrier Creams (2004) (20)
- Analysis of carbohydrate properties essential for melanogenesis in tyrosinases of cultured malignant melanoma cells by differential carbohydrate processing inhibition. (1990) (20)
- Mechanical methods for evaluating skin surface architecture in relation to wrinkling. (2001) (20)
- Isolation and biochemical characterization of tyrosinase‐rich GERL and coated vesicle in melanin synthesizing cells (1981) (20)
- Biochemical Characterization of Endothelin-converting Enzyme-1α in Cultured Skin-derived Cells and Its Postulated Role in the Stimulation of Melanogenesis in Human Epidermis* (2002) (20)
- A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum (2012) (19)
- Signaling Cascades Activated by UVB in Human Melanocytes Lead to the Increased Expression of Melanocyte Receptors, Endothelin B Receptor and c‐KIT (2018) (19)
- An Extract of Withania somnifera Attenuates Endothelin‐1‐stimulated Pigmentation in Human Epidermal Equivalents through the Interruption of PKC Activity Within Melanocytes (2011) (18)
- Diurnal variation affects age-related profile in skin thickness. (2001) (18)
- Carbon dioxide laser treatment promotes repair of the three‐dimensional network of elastic fibres in rat skin (2001) (18)
- Cumulative effect of surfactants on cutaneous horny layers: Lysosome labilizing action (1979) (18)
- The mechanism of hyperpigmentation in seborrhoeic keratosis involves the high expression of endothelin-converting enzyme-1alpha and TNF-alpha, which stimulate secretion of endothelin 1. (2001) (18)
- Fine wrinkle formation : etiology and prevention (1993) (17)
- Downregulated melanogenic paracrine cytokine linkages in hypopigmented palmoplantar skin (2008) (17)
- Damage to Human Hair Caused by Repeated Bleaching Combined with Daily Weathering during Daily Life Activities (2004) (17)
- Melanocyte Activation Mechanisms and Rational Therapeutic Treatments of Solar Lentigos (2019) (17)
- Treatment with Synthetic Pseudo-Ceramide Improves Atopic Skin Switching the Ceramide Profile to a Healthy Skin Phenotype. (2020) (17)
- Functions of the stratum corneum in systemic sclerosis as distinct from hypertrophic scar and keloid functions. (2002) (17)
- Strawberry seed extract and its major component, tiliroside, promote ceramide synthesis in the stratum corneum of human epidermal equivalents (2018) (17)
- Amelioration of lactic acid sensations in sensitive skin by stimulating the barrier function and improving the ceramide profile (2018) (16)
- Isolation and characterization of tyrosinase inhibitors and their differential action on melanogenic subcellular compartments in amelanotic and melanotic melanomas (1980) (16)
- Antimicrobial effect of zinc pyrithione (1982) (16)
- Cumulative effect of surfactants on cutaneous horny layers: Lysosomal activity of human keratin layers in vivo (1981) (15)
- Epithelial–mesenchymal interaction mechanisms leading to the over‐expression of neprilysin are involved in the UVB‐induced formation of wrinkles in the skin (2016) (15)
- [Physiological analysis of the facial skin by corneocyte morphology and stratum corneum turnover]. (1989) (14)
- Induction of melanization within hair bulb melanocytes in chinchilla mutant by melanogenic stimulants. (1988) (14)
- Characterization of melanogenesis in normal human epidermal melanocytes by chemical and ultrastructural analysis. (1996) (14)
- The inhibitory effect of zinc pyrithione on the epidermal proliferation of animal skins. (1982) (13)
- Recharacterization of the Nonlesional Dry Skin in Atopic Dermatitis through Disrupted Barrier Function (2004) (13)
- Down-regulated PAR-2 is associated in part with interrupted melanosome transfer in pigmented basal cell epithelioma. (2004) (13)
- Topical Ceramide Corrected Epidermal Cell Hyperproliferation and Stratum Corneum Dysmaturation in Atopic eczema (1997) (13)
- New inhibitors of melanogenesis, OH-3984 K1 and K2. II. Physico-chemical properties and structural elucidation. (1993) (12)
- Denaturing Action of Typical Anionic Surfactants on Several Proteins (1976) (12)
- An Extract of Withania somnifera Attenuates Endothelin‐1‐stimulated Pigmentation in Human Epidermal Equivalents through the Interruption of PKC Activity Within Melanocytes (2013) (12)
- [The role of intercellular lipids in the water-holding properties of the stratum corneum--recovery effect on experimentally-induced dry skin]. (1988) (12)
- Crucial role of fibroblast integrins alpha2 and beta1 in maintaining the structural and mechanical properties of the skin. (2007) (12)
- Photohapten TCSA painting plus UVA irradiation of murine skin augments the expression of MHC class II molecules and CD86 on Langerhans cells. (1999) (12)
- Study on Skin-Irritating and Biological Properties of Monoalkyl Phosphate Anionic Surfactants (1979) (11)
- Allergic contact dermatitis releases soluble factors that stimulate melanogenesis through activation of protein kinase C-related signal-transduction pathway. (1992) (11)
- Characterization of hair lipid images by argon sputter etching-scanning electron microscopy (2006) (11)
- Efficacy of Using Pseudoceramide-containing Cream for the Treatment of Atopic Dry Skin in Comparison with Urea Cream. (2002) (11)
- The Inhibitory Effects of Anti-Oxidants on Ultraviolet-Induced Up-Regulation of the Wrinkling-Inducing Enzyme Neutral Endopeptidase in Human Fibroblasts (2016) (11)
- Abrogating effect of N-linked carbohydrate modifiers on the stem cell factor and endothelin-1-stimulated epidermal pigmentation in human epidermal equivalents. (2013) (10)
- Withaferin A abolishes the stem cell factor-stimulated pigmentation of human epidermal equivalents by interrupting the auto-phosphorylation of c-KIT in human melanocytes (2014) (10)
- Paracrine Interactions of Melanocytes in Pigmentary Disorders (2007) (10)
- Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role (2021) (10)
- The effect of zinc pyrithione on human skin cells in vitro (1983) (10)
- The decreased secretion of hyaluronan by older human fibroblasts under physiological conditions is mainly associated with the down-regulated expression of hyaluronan synthases but not with the expression levels of hyaluronidases (2015) (10)
- Purification and Characterization of an Allergy-induced Melanogenic Stimulating Factor in Brownish Guinea Pig Skin* (1998) (10)
- Glucosamine abrogates the stem cell factor + endothelin-1-induced stimulation of melanogenesis via a deficiency in MITF expression due to the proteolytic degradation of CREB in human melanocytes (2018) (9)
- Analytical method to examine the effects of carbon dioxide lasers on skin: A study using wrinkles induced in hairless mice (2001) (9)
- Bioactive Maleic Anhydrides and Related Diacids from the Aquatic Hyphomycete Tricladium castaneicola. (2015) (8)
- Development of Synthetic Ceramide-based Biomimetic Skin Care Products. (1993) (7)
- Isolation and characterization of tyrosinase inhibitors and their differential action on melanogenic subcellular compartments in amelanotic and melanomas. (1980) (7)
- Clinical Test of Skin Care Products on Atopic Dry Skin (2000) (6)
- β-Sitosterol 3-O-D-glucoside increases ceramide levels in the stratum corneum via the up-regulated expression of ceramide synthase-3 and glucosylceramide synthase in a reconstructed human epidermal keratinization model (2021) (6)
- Control of melanogenesis and melanoma oncogenesis. (1988) (6)
- Role of asparagine‐linked carbohydrates in pulmonary metastasis of B16‐F10 murine melanoma cells: implication through glycosylation inhibition by nojirimycin (1992) (6)
- Reduced glutathione disrupts the intracellular trafficking of tyrosinase and tyrosinase-related protein-1 but not dopachrome tautomerase and Pmel17 to melanosomes, which results in the attenuation of melanization (2013) (6)
- Intracellular Signaling Mechanisms Involved in the Biological Effects of the Xanthophyll Carotenoid Astaxanthin to Prevent the Photo‐aging of the Skin in a Reactive Oxygen Species Depletion‐independent Manner: The Key Role of Mitogen and Stress‐activated Protein Kinase 1 (2018) (6)
- The Development of Monoalkyl Phosphate as a Low Skin Irritating Anionic Surfactant (1987) (6)
- Paracrine cytokine mechanisms underlying the hyperpigmentation of seborrheic keratosis in covered skin areas (2013) (6)
- A novel method for visualizing hair lipids at the cell membrane complex: argon sputter etching/scanning electron microscopy. (2006) (5)
- Effect of Chamomilla Extracts Application on UV-Induced Pigmentation (1999) (5)
- Solid-State 13C-NMR Studies on Elastic Property of the Stratum Corneum (1993) (5)
- A new inhibitor of melanogenesis, albocycline K3, produced by Streptomyces sp. OH-3984. (1996) (5)
- Efficacy of Pseudoceramide-containing Detergent Formulation for Treatment of Atopic Dermatitis and Asteatotic Eczema (2002) (5)
- Paracrine cytokine interaction between UVB-exposed epidermal keratinocytes and dermal fibroblasts in stimulating expression of skin fibroblast-derived elastase. (2012) (5)
- Successful protection of antigen specific dermatitic reaction in atopic dermatitis by topical O-acylceramides (1993) (5)
- Anti-aging and functional improvement effects for the skin by functional foods intakes：clinical effects on skin by oral ingestion of preparations containing Astaxanthin and Vitamins C and E (2013) (5)
- The Xanthophyll Carotenoid Astaxanthin has Distinct Biological Effects to Prevent the Photoaging of the Skin Even by its Postirradiation Treatment (2018) (5)
- Whitening effect of l-ascorbate-2-phosphate trisodium salt on solar lentigos (2019) (5)
- [The cumulative effect of surface active agents on human cutaneous horny layers]. (1976) (5)
- Possible eye-irritant test using polysaccharide-coated liposomes as a corneal epithelium model. (1987) (5)
- Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis. (2020) (4)
- [Vasodilating effects of NY-008 in ring preparation of rat aorta]. (1995) (4)
- Skin lighteners : An overview of the skin-lightening market in Japan, including an introduction to two new active ingredients (1996) (4)
- Acrolein vapor fixation in electron microscopy of the horny layer. (1983) (4)
- Sphingomyelin Deacylase, the Enzyme Involved in the Pathogenesis of Atopic Dermatitis, Is Identical to the β-Subunit of Acid Ceramidase (2020) (4)
- Mycosporine-like amino acids stimulate hyaluronan secretion by up-regulating hyaluronan synthase 2 via activation of the p38/MSK1/CREB/c-Fos/AP-1 axis (2020) (4)
- The Attenuated Secretion of Hyaluronan by UVA-Exposed Human Fibroblasts Is Associated with Up- and Downregulation of HYBID and HAS2 Expression via Activated and Inactivated Signaling of the p38/ATF2 and JAK2/STAT3 Cascades (2021) (4)
- Moisturizing Effect of Bath Additive Containing Cholesteryl Isostearate. (1994) (4)
- Structure and Function of Intercellular Lipis in the Stratum Corneum (1995) (3)
- Triangulation method for determining capillary blood flow and physical characteristics of the skin. (1999) (3)
- [Active tyrosinase site in melanin synthesizing cells; biochemical study of GERL (author's transl)]. (1978) (3)
- Effects of Oral Administration of Perillaldehyde on Its Contact Sensitivity in Guinea Pigs (1985) (2)
- Lipid abnormalities in atopic dermatitis. Discussion (2001) (2)
- Evaluation of Anionic Surfactants (1981) (2)
- Quantitative analysis of desmoglein-1 in the stratum corneum from UVB exposed skin (1992) (2)
- The Role of Elastases Secreted by Fibroblasts in Wrinkle Formation: Implication Through Selective Inhibition of Elastase Activity ¶ (2001) (2)
- Arenarol isolated from a marine sponge abrogates endothelin-1-stimulated melanogenesis by interrupting MEK phosphorylation in normal human melanocytes (2013) (2)
- [Active tyrosinase sites in melanin synthesizing cells; biochemical analysis of coated vesicles (author's transl)]. (1978) (2)
- A New Inhibitor of Melanogenesis, Albocycline K3, Produced by Streptomyces sp. OH‐3984 (1996) (2)
- [Plasminogen activator inhibitor activity of cultured cancer bearing and non-bearing xeroderma pigmentosum fibroblasts]. (1985) (1)
- THE INTERACTION OF PHOTOPROTECTIVE EFFECTS BETWEEN KERATINOCYTES AND MELANOCYTES VIA ENDOTHELIN-1 / STEM CELL FACTOR SIGNALINGS (2012) (1)
- Atopic dermatitis/Dry skin mechanism (1997) (1)
- The ceramide deficiency induced by IL-4 in the stratum corneum can be abrogated by rosiglitazone in human epidermal equivalents (2016) (1)
- Abnormal expression of sphingomyeline acylase results in ceramide deficiency in atopic dermatitis (1994) (1)
- The role of sphingosylphosphorylchorine generated due to the abnormal expression of sphingomyelin acylase in atopic dermatitis (1994) (1)
- ELECTROPHORETIC CHARACTERIZATION OF TYROSINASE IN THE COATED VESICLES OF MALIGNANT MELANOMA (1979) (1)
- 105 A new assay system of sphingomyelin deacylase and their biochemical characterization in atopic stratum corneum (1997) (1)
- Granulocyte / macrophage colony stimulating factor is an intrinsic keratinocyte-derived growth factor for human melanocytes in UVA melanogenesis (1993) (1)
- Metastatic Behavior and Tumorigenicity of a Human Melanoma Cell Line (MM‐RU) after Injection into Nude Mice (1993) (1)
- Newer Melanogenesis Control and Melanoma Eradication (1988) (1)
- Erratum to: An extract of Melia toosendan attenuates endothelin-1-stimulated pigmentation in human epidermal equivalents through the interruption of PKC activity within melanocytes (2013) (1)
- Essential role of eicosanoid production as an oncogene inducer in insulin-like growth factor-I stimulated mitogenesis of human keratinocytes (1993) (0)
- Amine derivatives and containing them dermatological preparations (1994) (0)
- Comparison between the data obtained with skin surface hygrometer and those with new-type tactile sensor (1992) (0)
- 144 The role of endothelin-1 in hyperpigmentation of seborrheic keratosis (1995) (0)
- Cosmetic compositions comprising lipid derived from corneal cells (1986) (0)
- 157 Down-regulation of silver locus protein in pheomelanogenic murine hair bulbs (1995) (0)
- アミジノ-L-プロリンの目尻の小じわに対する改善効果 (2002) (0)
- UVB stimulates TGase I expression via NFkB activation which is attenuated by astaxanthin through inactivation of MSK1 in human keratinocytes (2013) (0)
- [Plasminogen activator inhibitor activity of cultured normal human fibroblasts]. (1984) (0)
- Long-wave ultraviolet radiation-absorbing agent. (1985) (0)
- 147 Role of endothelin-1 in hyperpigmentation in senile freckle (1997) (0)
- Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes (2011) (0)
- Purification and characterization of allergy-induced melanogenic factor in brownish guinea pig skin (1992) (0)
- Localization of glucocerebrosidase within murine stratum corneum (1993) (0)
- Method for the inhibition of hair growth (1999) (0)
- Multi-channel sensor-probed laser doppler flow-metry for a precise evaluation of skin blood flow (1992) (0)
- Agents de prevention du vieillissement de la peau (1998) (0)
- Amine derivatives and compositions containing them dermatological preparations (1994) (0)
- Processing of glucosylceramides is required for maintenance of the epidermal barrier function (1992) (0)
- The pathogenic ceramide metabolizing enzyme sphingomyelin deacylase in atopic dermatitis is identical to the beta-subunit of acid ceramidase (2017) (0)
- Differential damages of UV exposures to three dimensional networks of elastic fibers during maturation of rat skin (1993) (0)
- A Nano-Emulsion Containing Ceramide-like Lipo-Amino Acid Cholesteryl Derivatives Improves Skin Symptoms in Patients with Atopic Dermatitis by Ameliorating the Water-Holding Function (2022) (0)
- EXPERIMENTAL ANIMAL FOR DEVELOPING WHITENING AGENS (1998) (0)
- 148 Expression of melanocortin 1 receptor(MC1-R) and endothelin B receptor (ETB-R) in cultured normal human melanocytes, nevus cells and melanoma cells (1997) (0)
- Reactivity of a Molecular Complex between Isobutyl Vinyl Ether and Maleic Anhydride (1971) (0)
- 178 Acute barrier disruption by acetone before sensitization augments murine contact hypersensitivity to dnfb but not FITC (1995) (0)
- Biological Characterization of a Unique Amino acid Derivative-surfactant, Lauroyl Beta-alanine in Relation to its Cutaneous Effect. (1993) (0)
- Contents Vol. 3, 2004 (2006) (0)
- Demonstration of early anagen-specific stimulatory factors within skin tissue for in vitro mesenchymal-epithelial interaction in collagen embedded hair follicle mixed culture (1993) (0)
- Inhibition of fibroblast-derived elastases can prevent UVB-induced wrinkle formation (1998) (0)
- Endothelin-1 secreted by human keratinocytes is an intrinsic growth factor for human melanocytes (1992) (0)
- Cutting Edge on Molecular Mechanisms of Skin Ageing and Its Rational Anti-Aging Treatments and Pathogenesis of Atopic Dermatitis (2021) (0)
- Inhibitor of melanin, a base of a derivative of cinnamic acid (1984) (0)
- Post-translational processing of melanogenesis subsequent to melanogenic protein expression and its regulation leading to the development of novel depigmenting agents (2008) (0)
- Table of Contents (1994) (0)
- Acute barrier disruption by acetone augments responsiveness of murine contact hypersensitivity (1994) (0)
- Functional analysis of ceramidase and sphingomyelinase in the stratum corneum of patients with atopic dermatitis (1993) (0)
- Experimental Allergic Dermatitis of Synthesized Primin in the Guinea Pig (1983) (0)
- [Behavior of prostaglandin in ultraviolet ray-induced erythema--in vitro analysis using xeroderma pigmentosum cells]. (1982) (0)
- 179 Immunological characterization of percutaneous sensitization with mite allergens in mice (1995) (0)
- Efficacy of 4-methoxydibenzoylmethane-2-carboxylic acid as a new broad-spectrum sunscreen (1990) (0)
- Nojirimycin (an α-glucosidase inhibitor) inhibits pulmonary metastasis of B16-F10 murine melanoma cells (1990) (0)
- P-hydroxyzimtamid derivatives and those containing melanin inhibitors. (1987) (0)
- Role of endothelin cascade between keratinocytes and melanocytes in hyperpigmentation in senile freckle (1998) (0)
- A method using repigmenting B-16 melanoma cells for screening anti-melanogenic agents (2008) (0)
- Preparation for external skin care. (1988) (0)
- Acknowledgement to Referees for Exogenous Dermatology 2004 (2006) (0)
- Ceramide Plays a Major Role in the Pathogenesis of Atopic Dermatitis. (2019) (0)
- Erratum to: Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes (2013) (0)
- Methoxy-4-carboxy-2 'Dibenzoylmethane and its salts (1985) (0)
- Contents Vol. 200, 2000 (2000) (0)
- Endothelin-3 enhances growth and migration of cultured normal human melanocytes, nevus cells and melanoma cells (1998) (0)
- Melanin inhibitor based on a cinnamic acid derivative (1984) (0)
- 135 The role of elastase secreted by fibroblasts during wrinkle formation (1997) (0)
- Clinical Evaluation of CurelR Medicated Cream in Patients with Atopic Dermatitis (2001) (0)
- Nutricosmetics for Protecting Healthy Skin from Ultraviolet Radiation-Induced Inflammation, Abnormal Keratinization and Hyperpigmentation (2015) (0)
- 142 Localization of heat shock protein 60 in melanosomes of melanocyte (1997) (0)
- 021 Regulation of elastase gene expression by cytokines (1996) (0)
- Erratum to: Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes (2013) (0)
- P-hydroxycinnamamide derivatives and melanin inhibitor containing them. (1987) (0)
- Characterization of cytokine expression in draining lymph nodes after percutaneous sensitization with protein antigens in barrier disruption model (1994) (0)
- Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis (2023) (0)
- Subject Index Vol. 3, 2004 (2006) (0)
- First preparation of hen egg yolk antibodies against human hair shaft and its immunological characteristics (1993) (0)
- Analysis of melanin control mechanisms by epidermal organ culture system (1990) (0)
- Withania somnifera Extract/Withaferin A as a Prospective Anti-pigmenting Agent (2017) (0)
- 136 Wrinkle effacement in mouse skin by a sphingosine derivative with a potential to supress elastase expression (1997) (0)
- Diurnal variation affects age-related profile in (2001) (0)
- Interruption of fibroblast elastase production and secretion by can repair UVB-induced wrinkles (1998) (0)
- The biological mechanism underlying UVB-induced wrinkling and its prevention (2003) (0)
- Retraction notice to "Paracrine cytokine interaction between UVB-exposed epidermal keratinocytes and dermal fibroblasts in stimulating expression of skin fibroblast-derived elastase" [Cytokine 59 (2012) 166–175]. (2013) (0)
- To be or not to be Photopigmented, that is the Question (2018) (0)
- The role of eicosanoids in growth factor stimulated mitogenesis of human keratinocytes (1992) (0)
- Subject Index Vol. 200, 2000 (2000) (0)
- 132 Regulation of endothelin receptors on human melanocytes by keratinocyte-derived factors (1996) (0)
- Desmoglein-1 content in the stratum corneum is directly involved in their adhesive properties (1993) (0)
- Appearance skin care preparation. (1988) (0)
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