Geoffrey J. Barton
#130,334
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Professor of Bioinformatics at the University of Dundee
Geoffrey J. Barton's AcademicInfluence.com Rankings
Geoffrey J. Bartonbiology Degrees
Biology
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Bioinformatics
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#94
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Why Is Geoffrey J. Barton Influential?
(Suggest an Edit or Addition)Geoffrey J. Barton's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Jalview Version 2—a multiple sequence alignment editor and analysis workbench (2009) (7580)
- The Jpred 3 secondary structure prediction server (2008) (1589)
- The Jalview Java alignment editor (2004) (1544)
- JPred4: a protein secondary structure prediction server (2015) (1439)
- ALSCRIPT: a tool to format multiple sequence alignments. (1993) (1091)
- JPred: a consensus secondary structure prediction server (1998) (1039)
- Application of multiple sequence alignment profiles to improve protein secondary structure prediction (2000) (832)
- Draft Genome Sequence of the Sexually Transmitted Pathogen Trichomonas vaginalis (2007) (739)
- Evaluation and improvement of multiple sequence methods for protein secondary structure prediction (1999) (683)
- Multiple protein sequence alignment from tertiary structure comparison: Assignment of global and residue confidence levels (1992) (680)
- Identification of multiple distinct Snf2 subfamilies with conserved structural motifs (2006) (661)
- Draft Genome of the Filarial Nematode Parasite Brugia malayi (2007) (639)
- Protein sequence alignments: a strategy for the hierarchical analysis of residue conservation (1993) (578)
- Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. (2009) (549)
- Emerging roles of pseudokinases. (2006) (523)
- A strategy for the rapid multiple alignment of protein sequences. Confidence levels from tertiary structure comparisons. (1987) (503)
- How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use? (2016) (478)
- System-Wide Changes to SUMO Modifications in Response to Heat Shock (2009) (478)
- Prediction of protein secondary structure and active sites using the alignment of homologous sequences. (1987) (451)
- Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes (1995) (389)
- A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells* (2011) (357)
- High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli (2010) (284)
- A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization (2011) (274)
- GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes (2004) (259)
- PIPs: human protein–protein interaction prediction database (2008) (232)
- OXBench: A benchmark for evaluation of protein multiple sequence alignment accuracy (2003) (227)
- Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins. (2010) (216)
- Protein multiple sequence alignment and flexible pattern matching. (1990) (205)
- PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A–SIK–CRTC3 Pathway (2013) (200)
- Human miRNA Precursors with Box H/ACA snoRNA Features (2009) (193)
- Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification (2019) (189)
- Structural features can be unconserved in proteins with similar folds. An analysis of side-chain to side-chain contacts secondary structure and accessibility. (1994) (173)
- Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics (2021) (172)
- Conservation analysis and structure prediction of the protein serine/threonine phosphatases. Sequence similarity with diadenosine tetraphosphatase from Escherichia coli suggests homology to the protein phosphatases. (1994) (166)
- Continuous and discontinuous domains: An algorithm for the automatic generation of reliable protein domain definitions (1995) (165)
- Classification and functional annotation of eukaryotic protein kinases (2007) (163)
- Characterization and prediction of protein nucleolar localization sequences (2010) (157)
- Direct Sequencing of Arabidopsis thaliana RNA Reveals Patterns of Cleavage and Polyadenylation (2012) (151)
- E-MSD: an integrated data resource for bioinformatics (2004) (151)
- Probabilistic prediction and ranking of human protein-protein interactions (2007) (147)
- 14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides (2015) (140)
- Amino acid sequence analysis of the annexin super-gene family of proteins. (1991) (140)
- A structural analysis of phosphate and sulphate binding sites in proteins. Estimation of propensities for binding and conservation of phosphate binding sites. (1994) (139)
- Protein fold recognition by mapping predicted secondary structures. (1996) (138)
- Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects (2013) (135)
- Identification of human miRNA precursors that resemble box C/D snoRNAs (2011) (132)
- Structural similarity between the p17 matrix protein of HIV-1 and interferon-γ (1994) (132)
- Flexible protein sequence patterns. A sensitive method to detect weak structural similarities. (1990) (128)
- NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins (2011) (125)
- The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. (2007) (122)
- The Scottish Structural Proteomics Facility: targets, methods and outputs (2010) (121)
- Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation (2012) (120)
- Evaluation and improvements in the automatic alignment of protein sequences. (1987) (118)
- Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis (2014) (115)
- PTEN Protein Phosphatase Activity Correlates with Control of Gene Expression and Invasion, a Tumor-Suppressing Phenotype, But Not with AKT Activity (2012) (110)
- Conservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domains (1992) (109)
- TarO: a target optimisation system for structural biology (2008) (105)
- Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases (2009) (105)
- Erratum: How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use? (2016) (97)
- SCANPS: a web server for iterative protein sequence database searching by dynamic programing, with display in a hierarchical SCOP browser (2008) (95)
- Java bioinformatics analysis web services for multiple sequence alignment—JABAWS:MSA (2011) (94)
- Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases (2008) (91)
- Proteotoxic stress reprograms the chromatin landscape of SUMO modification (2015) (85)
- Scop: structural classification of proteins. (1994) (83)
- Visualization of multiple alignments, phylogenies and gene family evolution (2010) (83)
- Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment (2015) (83)
- The limits of protein secondary structure prediction accuracy from multiple sequence alignment. (1993) (80)
- Human box C/D snoRNA processing conservation across multiple cell types (2011) (79)
- The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe (2007) (77)
- Mutational analysis of human papillomavirus E4 proteins: identification of structural features important in the formation of cytoplasmic E4/cytokeratin networks in epithelial cells (1994) (73)
- SNAPPI-DB: a database and API of Structures, iNterfaces and Alignments for Protein–Protein Interactions (2007) (73)
- ParCrys: a Parzen window density estimation approach to protein crystallization propensity prediction (2008) (70)
- Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma (2012) (69)
- Identification of functional residues and secondary structure from protein multiple sequence alignment. (1996) (67)
- The kinomes of apicomplexan parasites. (2012) (64)
- PDBe-KB: a community-driven resource for structural and functional annotations (2019) (63)
- Ambisonic Decoders for HDTV (1992) (63)
- Transcription Termination and Chimeric RNA Formation Controlled by Arabidopsis thaliana FPA (2013) (59)
- A normalised scale for structural genomics target ranking: The OB‐Score (2006) (56)
- The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative polyadenylation (2013) (56)
- Quantification of the variation in percentage identity for protein sequence alignments (2006) (56)
- Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling (2014) (56)
- 3Dee: a database of protein structural domains (2001) (56)
- Protein secondary structure prediction. (1995) (55)
- MACSIMS : multiple alignment of complete sequences information management system (2006) (54)
- Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo (2014) (52)
- The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4 (2011) (48)
- Analysis of Human Small Nucleolar RNAs (snoRNA) and the Development of snoRNA Modulator of Gene Expression Vectors (2010) (47)
- Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework (2017) (46)
- Alignment of Biological Sequences with Jalview. (2020) (46)
- An efficient algorithm to locate all locally optimal alignments between two sequences allowing for gaps (1993) (45)
- The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction (2008) (45)
- Elevated O‐GlcNAc Levels Activate Epigenetically Repressed Genes and Delay Mouse ESC Differentiation Without Affecting Naïve to Primed Cell Transition (2014) (44)
- Genome Analysis of the Unicellular Green Alga Chlamydomonas reinhardtii Indicates an Ancient Evolutionary Origin for Key Pattern Recognition and Cell-Signaling Protein Families (2008) (44)
- Global network analysis of drug tolerance, mode of action and virulence in methicillin-resistant S. aureus (2011) (43)
- AIDS vaccine predictions (1987) (40)
- Prediction of domain organisation and secondary structure of thyroid peroxidase, a human autoantigen involved in destructive thyroiditis (1990) (37)
- Proteus: an R package for downstream analysis of MaxQuant output (2018) (36)
- Identification of a glycosylphosphatidylinositol anchor‐modifying β1‐3 N‐acetylglucosaminyl transferase in Trypanosoma brucei (2009) (35)
- Estimation of P-values for global alignments of protein sequences (2001) (34)
- Protein structural domains: Analysis of the 3Dee domains database (2001) (33)
- Biological units and their effect upon the properties and prediction of protein-protein interactions. (2006) (30)
- Protein Sequence Alignment and Database Scanning (2001) (29)
- An SH2—SH3 domain hybrid (1993) (28)
- Improved Annotation of 3′ Untranslated Regions and Complex Loci by Combination of Strand-Specific Direct RNA Sequencing, RNA-Seq and ESTs (2013) (26)
- XANNpred: Neural nets that predict the propensity of a protein to yield diffraction-quality crystals (2010) (25)
- Secondary structure prediction for modelling by homology. (1993) (24)
- LOPAL and SCAMP: techniques for the comparison and display of protein structures (1988) (23)
- ProtEST: protein multiple sequence alignments from expressed sequence tags (2000) (23)
- Prediction of antigenic determinants and secondary structures of the major AIDS virus proteins (1987) (23)
- PDBe-KB: collaboratively defining the biological context of structural data (2021) (22)
- A new family of transcription factors (2008) (22)
- JABAWS 2.2 distributed web services for Bioinformatics: protein disorder, conservation and RNA secondary structure (2018) (21)
- A knowledge-based architecture for protein sequence analysis and structure prediction. (1990) (21)
- Chromosome evolution and the genetic basis of agronomically important traits in greater yam (2021) (20)
- Protein structure prediction (1993) (20)
- Protein sequence alignment techniques. (1998) (19)
- Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA (2020) (19)
- Secondary structure prediction from multiple sequence data: blood clotting factor XIII and Yersinia protein-tyrosine phosphatase. (2009) (18)
- E-MSD: an integrated data resource for bioinformatics. (2004) (18)
- Identifying plant genes shaping microbiota composition in the barley rhizosphere (2021) (18)
- Missense variants in ACE2 are predicted to encourage and inhibit interaction with SARS-CoV-2 Spike and contribute to genetic risk in COVID-19 (2020) (18)
- Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer (2017) (17)
- Scanning protein sequence databanks using a distributed processing workstation network (1991) (16)
- Relative Abundance of Transcripts ( RATs): Identifying differential isoform abundance from RNA-seq (2019) (15)
- Nanopore direct RNA sequencing maps an Arabidopsis N6 methyladenosine epitranscriptome (2019) (15)
- Deposition of macromolecular structures. (1998) (14)
- Yanocomp: robust prediction of m6A modifications in individual nanopore direct RNA reads (2021) (13)
- A comparison of SCOP and CATH with respect to domain–domain interactions (2007) (13)
- Computer speed and sequence comparison. (1992) (12)
- Detection and Mitigation of Spurious Antisense Reads with RoSA (2018) (12)
- The AMPS package for multiple protein sequence alignment. (1994) (12)
- Increased Coverage Obtained by Combination of Methods for Protein Sequence Database Searching (2003) (11)
- The Dundee Resource for Sequence Analysis and Structure Prediction (2019) (11)
- Jalview: Visualization and Analysis of Molecular Sequences, Alignments, and Structures (2005) (11)
- Identifying differential isoform abundance with RATs: a universal tool and a warning (2017) (10)
- PNAC: a protein nucleolar association classifier (2011) (9)
- Detection and mitigation of spurious antisense expression with RoSA (2019) (9)
- Ambisonic Surround-Sound Mixing for Multitrack Studios (1984) (9)
- Sequence alignment for molecular replacement (2007) (9)
- Interaction of synthetic peptides from annexin I and uteroglobin with lipid monolayers and their effect on phospholipase A2 activity. (1990) (8)
- Computational approaches to selecting and optimising targets for structural biology (2011) (8)
- 2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing (2020) (8)
- PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities (2011) (8)
- Human protein-protein interaction prediction (2010) (7)
- A study of the structural properties of sites modified by the O-linked 6-N-acetylglucosamine transferase (2017) (7)
- How well do RNA-Seq differential gene expression tools perform in higher eukaryotes? (2016) (7)
- Protein fold recognition from secondary structure assignments (1995) (7)
- How well do RNA-Seq differential gene expression tools perform in a complex eukaryote? A case study in Arabidopsis thaliana (2019) (7)
- Human Missense Variation is Constrained by Domain Structure and Highlights Functional and Pathogenic Residues (2017) (7)
- How well do RNA-Seq differential gene expression tools perform in a eukaryote with a complex transcriptome? (2017) (6)
- Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity predictions of interface variants (2022) (6)
- A PROLOG approach to analysing protein structure (1990) (6)
- Web of intrigue (1996) (6)
- Improved annotation with de novo transcriptome assembly in four social amoeba species (2017) (6)
- Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase. (2007) (6)
- Creation and analysis of protein multiple sequence alignments. (2001) (5)
- Disease related single point mutations alter the global dynamics of a tetratricopeptide (TPR) α-solenoid domain (2019) (5)
- AlmostSignificant: simplifying quality control of high-throughput sequencing data (2016) (5)
- Visual Representation of Database Search Results: The RHIMS Plot (2003) (4)
- Ankyrin repeats in context with human population variation (2021) (4)
- Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase. (2007) (4)
- Missense variants in human ACE2 modify binding to SARS-CoV-2 Spike (2021) (3)
- Structural and Functional Analysis of the S-Layer Protein from Bacillus stearothermophilus (1993) (3)
- m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5’ splice site (2022) (3)
- Activity Expression and Invasion , a Tumor-Suppressing Phenotype , But Not with PTEN Protein Phosphatase Activity Correlates with Control of Gene ` (2012) (3)
- Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition (2014) (3)
- The relationship between domain-domain interaction orientation and sequence similarity (2007) (2)
- Generation and interpretation of protein sequence and structural multiple alignments (1992) (2)
- A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation (2011) (2)
- Multiple Sequence Alignment and Flexible Pattern Matching (1992) (2)
- The RNA-binding protein FPA regulates flg22-triggered defense responses and transcription factor activity by alternative (2013) (1)
- java2script/SwingJS for bioinformatics: Reintroducing Jalview on the Web as JalviewJS (2019) (1)
- New developments to SCANPS : High performance parallel iterated protein sequence searching with full dynamic programming and onthe-fly statistics (1)
- Correction: A study of the structural properties of sites modified by the O-linked 6-N-acetylglucosamine transferase (2017) (1)
- Correction to: Alignment of Biological Sequences with Jalview. (2021) (1)
- Detection and mitigation of spurious antisense expression with RoSA [version 1; peer review: 2 approved with reservations] (2021) (1)
- Dicer-dependent small RNAs derived from tRNAs Filtering of deep sequencing data reveals the existence of abundant Material Supplemental (2009) (1)
- Continuous and discontinuous domains : An algorithm for the automatic generation of protein domain definitionsreliable (2006) (0)
- Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework (2017) (0)
- Large knowledge based applications in molecular biology and genetics (1990) (0)
- 1 The kinomes of apicomplexan parasites (2013) (0)
- Prediction of Protein Structure from Multiple Sequence Alignment (1993) (0)
- Detecting Structural Similarity from Protein Sequence Comparison (2006) (0)
- Visualising Variants on Structure with Jalview (2019) (0)
- Transcriptome analysis of skin reveals differences between atopic eczema cases stratified for filaggrin genotype (2012) (0)
- 2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing (2021) (0)
- Distributed Web services for bioinformatics: Multiple sequence alignment, conservation and protein disorder (2011) (0)
- Development of a Computational Pipeline For Automated Prediction of Bacterial Transcription Factor Binding Sites (2006) (0)
- A K for and nowledge-based architecture protein sequence analysis structure prediction (2006) (0)
- HIGH RESOLUTION STRUCTURE OF SPT WITH PLP INTERNAL ALDIMINE (2007) (0)
- A tool and a warning: differential isoform usage with RATs (2017) (0)
- Prediction of transcription factor binding sites in bacterial genomes : case study with Pectobacterium atrosepticum (2006) (0)
- Simple jury predicts protein secondary structure best (2003) (0)
- Improved annotation with de novo transcriptome assembly in four social amoeba species (2016) (0)
- 1 1 m 6 A modification of U 6 snRNA modulates 2 usage of two major classes of pre-mRNA 5 ’ 3 splice site 4 5 (0)
- Helicos direct RNA sequencing of FPA mutants and overexpressors (2020) (0)
- Re: letter to the editor regarding deposition of 3D structural studies of biological macromolecules. (1998) (0)
- Low resolution structure of SPT (2007) (0)
- BIOINFORMATICS The Jalview Java alignment editor (2004) (0)
- Electronic publishing and the biochemist (1995) (0)
- Artificial Intelligence and Molecular Biology.Lawrence Hunter (1995) (0)
- Getting to grips with sequences. Computational Molecular Biology‐Sources and Methods for Sequence Analysis (1989). Edited by Arthur Lesk. Oxford University Press. Oxford, Pp. 254. £25.00 (1989) (0)
- Text-Translat ion Al ignment : Three Languages Are Bet ter Than Two * (2002) (0)
- Single-molecule transcriptomics of atopic eczema in human skin (2012) (0)
- RESEARCH INTO METABOLIC DISEASES (1997) (0)
- DEV112623 3266..3276 (2014) (0)
- Prediction and ranking of human protein-protein interactions within a Bayesian framework (2007) (0)
- Crystallization and X-ray diffraction studies of recombinant human platelet-derived endothelial cell growth factor (1993) (0)
- Digital Analysis of Quantisation Errors in Digital Signal Processing (1985) (0)
- ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (MANGANESE COMPLEX) (1998) (0)
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