Georg Nagel
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Biology
Why Is Georg Nagel Influential?
(Suggest an Edit or Addition)According to Wikipedia, Georg Nagel is a biophysicist and professor at the Department for Neurophysiology at the University of Würzburg in Germany. His research is focused on microbial photoreceptors and the development of optogenetic tools.
Georg Nagel's Published Works
Published Works
- Millisecond-timescale, genetically targeted optical control of neural activity (2005) (4141)
- Channelrhodopsin-2, a directly light-gated cation-selective membrane channel (2003) (2345)
- Multimodal fast optical interrogation of neural circuitry (2007) (1652)
- Channelrhodopsin-1: A Light-Gated Proton Channel in Green Algae (2002) (1024)
- Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses (2005) (900)
- Light-Induced Activation of Distinct Modulatory Neurons Triggers Appetitive or Aversive Learning in Drosophila Larvae (2006) (595)
- Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil Bacterium Beggiatoa*♦ (2010) (315)
- Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation (1992) (311)
- Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. (1994) (270)
- Spectral characteristics of the photocycle of channelrhodopsin-2 and its implication for channel function. (2008) (239)
- Fast manipulation of cellular cAMP level by light in vivo (2007) (232)
- Structural guidance of the photocycle of channelrhodopsin-2 by an interhelical hydrogen bond. (2010) (210)
- The protein kinase A-regulated cardiac CI− channel resembles the cystic fibrosis transmembrane conductance regulator (1992) (167)
- Channelrhodopsins: directly light-gated cation channels. (2005) (165)
- Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit (2011) (163)
- Channelrhodopsin-2–XXL, a powerful optogenetic tool for low-light applications (2014) (152)
- The CFTR chloride channel of mammalian heart. (1995) (145)
- Direct action of genistein on CFTR (1997) (140)
- Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. (2001) (138)
- "Vision" in single-celled algae. (2004) (116)
- Optogenetics: 10 years after ChR2 in neurons—views from the community (2015) (112)
- Conformational changes of channelrhodopsin-2. (2009) (109)
- Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons (2017) (109)
- A Reevaluation of Substrate Specificity of the Rat Cation Transporter rOCT1* (1997) (98)
- Mechanism of Electrogenic Cation Transport by the Cloned Organic Cation Transporter 2 from Rat* (2000) (97)
- Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp (2015) (89)
- From channelrhodopsins to optogenetics (2013) (82)
- Functional expression of bacteriorhodopsin in oocytes allows direct measurement of voltage dependence of light induced H+ pumping (1995) (79)
- Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2. (2003) (77)
- PACα– an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans (2011) (77)
- Voltage dependence of proton pumping by bacteriorhodopsin is regulated by the voltage-sensitive ratio of M1 to M2. (1998) (75)
- Electrophysiological characterization of specific interactions between bacterial sensory rhodopsins and their transducers. (2001) (74)
- Na+,K(+)-ATPase pump currents in giant excised patches activated by an ATP concentration jump. (1996) (73)
- Non‐specific activation of the epithelial sodium channel by the CFTR chloride channel (2001) (66)
- Probing the sensory rhodopsin II binding domain of its cognate transducer by calorimetry and electrophysiology. (2003) (60)
- Dual Effects of Adp and Adenylylimidodiphosphate on Cftr Channel Kinetics Show Binding to Two Different Nucleotide Binding Sites (1999) (59)
- Optogenetic Long-Term Manipulation of Behavior and Animal Development (2011) (57)
- A LOV-domain-mediated blue-light-activated adenylate (adenylyl) cyclase from the cyanobacterium Microcoleus chthonoplastes PCC 7420. (2013) (56)
- CFTR fails to inhibit the epithelial sodium channel ENaC expressed in Xenopus laevis oocytes (2005) (53)
- Na+ currents generated by the purified (Na+ + K+)-ATPase on planar lipid membranes. (1987) (50)
- The voltage-dependent proton pumping in bacteriorhodopsin is characterized by optoelectric behavior. (2001) (49)
- Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain (2018) (43)
- Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants (2013) (41)
- Microbial rhodopsins in the spotlight (2010) (40)
- Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans (2018) (36)
- Protein kinase‐independent activation of CFTR by phosphatidylinositol phosphates (2004) (36)
- Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition (2018) (34)
- Crosslinked casein-based micelles as a dually responsive drug delivery system (2018) (33)
- Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps (2020) (31)
- Two-component cyclase opsins of green algae are ATP-dependent and light-inhibited guanylyl cyclases (2018) (31)
- Voltage and substrate dependence of the inverse transport mode of the rabbit Na+/glucose cotransporter (SGLT1) (2000) (30)
- Differential function of the two nucleotide binding domains on cystic fibrosis transmembrane conductance regulator. (1999) (30)
- Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling (2021) (29)
- Comparison of Na+/K(+)-ATPase pump currents activated by ATP concentration or voltage jumps. (1997) (29)
- Charge movements via the cardiac Na,K-ATPase. (1992) (26)
- Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model. (2017) (25)
- Apparent affinity of CFTR for ATP is increased by continuous kinase activity (2003) (24)
- Increases in Intracellular Calcium Triggered by Channelrhodopsin-2 Potentiate the Response of Metabotropic Glutamate Receptor mGluR7* (2008) (24)
- A novel rhodopsin phosphodiesterase from Salpingoeca rosetta shows light-enhanced substrate affinity. (2018) (23)
- Biophysical characterisation of electrofused giant HEK293-cells as a novel electrophysiological expression system. (2006) (22)
- Regulation of CFTR channel gating. (1994) (22)
- Mutated Channelrhodopsins with Increased Sodium and Calcium Permeability (2019) (20)
- Matrix Metalloproteinase-sensitive Multistage Nanogels Promote Drug Transport in 3D Tumor Model (2020) (20)
- Negative charged threonine 95 of c-Jun is essential for c-Jun N-terminal kinase-dependent phosphorylation of threonine 91/93 and stress-induced c-Jun biological activity. (2008) (20)
- Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition (2019) (19)
- Optogenetic control of plant growth by a microbial rhodopsin (2021) (18)
- Rapid chemical kinetic techniques for investigations of neurotransmitter receptors expressed in Xenopus oocytes. (1996) (17)
- Detection and Definition of Scotomata of the Central Visual Field by Computer Methods (1981) (16)
- Optogenetic control of the guard cell membrane potential and stomatal movement by the light-gated anion channel GtACR1 (2021) (15)
- Mechanistic insights in light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACα) (2009) (14)
- Voltage and Ca2+ Dependence of Pre–Steady-State Currents of the Na-Ca Exchanger Generated by Ca2+ Concentration Jumps (2001) (12)
- Modular approach for theranostic polymer conjugates with activatable fluorescence: Impact of linker design on the stimuli‐induced release of doxorubicin (2018) (10)
- Dendritic polymer imaging systems for the evaluation of conjugate uptake and cleavage. (2015) (9)
- Temperature-Enhanced Follicular Penetration of Thermoresponsive Nanogels (2018) (8)
- PACmn for improved optogenetic control of intracellular cAMP (2021) (8)
- Pump currents generated by renal Na+K+-ATPase and gastric H+K+-ATPase on black lipid membranes. (1988) (8)
- Extending the Anion Channelrhodopsin-Based Toolbox for Plant Optogenetics (2021) (8)
- Investigation of charge translocation by ion pumps and carriers using caged substrates. (1998) (7)
- An engineered membrane-bound guanylyl cyclase with light-switchable activity (2021) (6)
- CFTR, investigated with the two-electrode voltage-clamp technique: the importance of knowing the series resistance. (2004) (6)
- Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide‐gated channels (2021) (5)
- Modified Rhodopsins From Aureobasidium pullulans Excel With Very High Proton-Transport Rates (2021) (4)
- A Dual Fluorescence–Spin Label Probe for Visualization and Quantification of Target Molecules in Tissue by Multiplexed FLIM–EPR Spectroscopy (2021) (4)
- Advances and prospects of rhodopsin-based optogenetics in plant research. (2021) (4)
- Quantitative analysis of ATP-dependent gating of CFTR. (2002) (4)
- Charge Translocation of H,K‐ATPase and Na,K‐ATPase (1992) (4)
- Chapter 12:Responsive Nanogels for Anti-cancer Therapy (2017) (3)
- Action potentials in Xenopus oocytes triggered by blue light (2020) (3)
- PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development (2021) (3)
- Irradiation Behavior of Submerged Arc Welding Materials with Different Copper Content (2000) (3)
- Pump currents generated by renal Na+K+-ATPase on black lipid membranes. (1988) (3)
- Voltage and Ca(2+) dependence of pre-steady-state currents of the Na-Ca exchanger generated by Ca(2+) concentration jumps. (2001) (2)
- Optogenetic tools for manipulation of cyclic nucleotides, functionally coupled to CNG-channels (2020) (2)
- Characterization and Modification of Light-Sensitive Phosphodiesterases from Choanoflagellates (2022) (2)
- Oxidation of reducing end groups in celluloses according to different protocols (2005) (2)
- mem-iLID, a fast and economic protein purification method (2021) (2)
- Transient Currents of Na+/K+‐ATPase in Giant Patches from Guinea Pig Cardiomyocytes Induced by ATP Concentration Jumps or Voltage Pulses (1997) (1)
- [New gelatine-free TBE vaccines with improved safety profile]. (2006) (1)
- Visual function restoration with a highly sensitive and fast Channelrhodopsin in blind mice (2022) (1)
- Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes (2022) (1)
- Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition (2019) (0)
- In Vivo and In Vitro Characterization of Cyclase and Phosphodiesterase Rhodopsins. (2022) (0)
- Characterization and Application of Natural Light-Sensitive Proteins (2009) (0)
- Coupling the Cardiac Voltage-Gated Sodium Channel to Channelrhodopsin-2 Generates Novel Optical Switches for Action Potential Studies (2022) (0)
- Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain (2018) (0)
- Prevention of Myopia in Children (2017) (0)
- Optogenetic manipulation of cGMP highlights PDE5 as the predominant cGMP-hydrolyzing PDE in megakaryocytes (2021) (0)
- Light-control of cellular cAMP, Ca, and Vm by microbial photoreceptors (2009) (0)
- Tailoring baker’s yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin (2023) (0)
- The Ca/Ca Exchange Mode of the Na/Ca Exchanger Investigated by Photolytic Ca2+ Concentration Jumps (2002) (0)
- Use of biological photoreceptor as ion channels directly controlled by light. (2003) (0)
- Use of biological photoreceptor as a directly light-controlled ion channels (2003) (0)
- PACmn for improved optogenetic control of intracellular cAMP (2021) (0)
- Oxidation of reducing endgroups in cellulose according to different approaches (2005) (0)
- Two-component cyclase opsins of green algae are ATP-dependent and light-inhibited guanylyl cyclases (2018) (0)
- Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants (2013) (0)
- Na+,K+‐ATPase Pump Currents Activated by an ATP Concentration Jump Comparison of Studies with Purified Membrane fragments and Giant excised Patches a (1997) (0)
- CFTR as a Regulator of the Epithelial sodium Channel – What ' s the Problem ? (2003) (0)
- Rational Design of Responsive Prodrug-based Nanomedicines for Antitumor Therapy (2019) (0)
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