Georges F. Koob
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(Suggest an Edit or Addition)Georges F. Koob's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neurocircuitry of Addiction (2021) (3654)
- Drug Addiction, Dysregulation of Reward, and Allostasis (2001) (2656)
- Drug abuse: hedonic homeostatic dysregulation. (1997) (2450)
- Drugs of abuse: anatomy, pharmacology and function of reward pathways. (1992) (2130)
- Cellular and molecular mechanisms of drug dependence. (1988) (2071)
- Neurobiology of addiction: a neurocircuitry analysis. (2016) (1757)
- Addiction and the brain antireward system. (2008) (1236)
- Neurobiologic Advances from the Brain Disease Model of Addiction. (2016) (1083)
- Transition from moderate to excessive drug intake: change in hedonic set point. (1998) (1068)
- The Neurobiology of Addiction (2005) (968)
- A Role for Brain Stress Systems in Addiction (2008) (927)
- Plasticity of reward neurocircuitry and the 'dark side' of drug addiction (2005) (923)
- Corticotropin Releasing Factor Receptor 1–Deficient Mice Display Decreased Anxiety, Impaired Stress Response, and Aberrant Neuroendocrine Development (1998) (856)
- Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress (2000) (835)
- Stress, dysregulation of drug reward pathways, and the transition to drug dependence. (2007) (835)
- Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens (1980) (754)
- Corticotropin releasing factor produces behavioural activation in rats (1982) (747)
- Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis (1998) (742)
- Dopamine, schizophrenia, mania, and depression: Toward a unified hypothesis of cortico-striatopallido-thalamic function (1987) (695)
- Alcoholism: allostasis and beyond. (2003) (692)
- Dramatic decreases in brain reward function during nicotine withdrawal (1998) (675)
- Neuroscience of Addiction (1998) (662)
- Neurobiological mechanisms for opponent motivational processes in addiction (2008) (650)
- Effects of moderate alcohol consumption on the central nervous system. (1998) (642)
- Neural Mechanisms of Drug Reinforcement a (1992) (629)
- Neurocircuitry of Addiction (2010) (628)
- Drug dependence: stress and dysregulation of brain reward pathways. (1998) (624)
- Corticotropin-releasing factor, norepinephrine, and stress (1999) (621)
- The neurobiology of drug addiction. (1997) (590)
- Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide (1996) (571)
- Neurocircuitry targets in ethanol reward and dependence. (1998) (564)
- Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty. (1982) (556)
- Neurobiological mechanisms in the transition from drug use to drug dependence (2004) (553)
- A role for corticotropin releasing factor and urocortin in behavioral responses to stressors (1999) (545)
- Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. (1993) (543)
- Postcocaine anhedonia: An animal model of cocaine withdrawal and its reversal by pharmacological treatments Athina Markou, M.A., Richard L. Hauger, M.D., George F. Koob, Ph.D. Department of Neuropharmacology, Research Institute of Scripps Clinic, La Jolla, CA 92037 (1991) (519)
- Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. (2005) (496)
- A key role for corticotropin-releasing factor in alcohol dependence (2007) (493)
- Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses (1994) (490)
- Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats (1982) (473)
- Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. (1993) (460)
- Sex Differences in Animal Models: Focus on Addiction (2016) (460)
- The Development and Maintenance of Drug Addiction (2014) (433)
- Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats (1996) (429)
- Neurobiological substrates for the dark side of compulsivity in addiction (2009) (426)
- Effects of 6-hydroxydopamine lesions of the nucleus accumbens septi and olfactory tubercle on feeding, locomotor activity, and amphetamine anorexia in the rat. (1978) (424)
- Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor. (2002) (423)
- Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal (1993) (406)
- Addiction as a stress surfeit disorder (2014) (390)
- Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. (2000) (389)
- The conception of the ABCD study: From substance use to a broad NIH collaboration (2017) (386)
- Animal models of drug craving (2005) (386)
- Role of different brain structures in the expression of the physical morphine withdrawal syndrome. (1992) (380)
- Chemical and biological characterization of corticotropin releasing factor. (1983) (379)
- The neurobiology of addiction: a neuroadaptational view relevant for diagnosis. (2006) (376)
- Corticotropin-Releasing Factor within the Central Nucleus of the Amygdala Mediates Enhanced Ethanol Self-Administration in Withdrawn, Ethanol-Dependent Rats (2006) (371)
- The role of the dynorphin–κ opioid system in the reinforcing effects of drugs of abuse (2010) (366)
- Neurobiological evidence for hedonic allostasis associated with escalating cocaine use (2002) (365)
- Anxiolytic-Like Action of Neuropeptide Y: Mediation by Y1 Receptors in Amygdala, and Dissociation from Food Intake Effects (1993) (361)
- Functional Interaction between Opioid and Cannabinoid Receptors in Drug Self-Administration (2001) (360)
- Corticotropin-Releasing Factor in Brain: A Role in Activation, Arousal, and Affect Regulation (2004) (358)
- Theoretical frameworks and mechanistic aspects of alcohol addiction: alcohol addiction as a reward deficit disorder. (2013) (356)
- Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. (2006) (356)
- Neural substrates of opiate withdrawal (1992) (349)
- Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics (1986) (348)
- Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats (2004) (345)
- Brain stress systems in the amygdala and addiction (2009) (344)
- Pharmacological Evidence for a Motivational Role of κ-Opioid Systems in Ethanol Dependence (2008) (344)
- Excessive Ethanol Drinking Following a History of Dependence: Animal Model of Allostasis (2000) (342)
- Persistent Increase in the Motivation to Take Heroin in Rats with a History of Drug Escalation (2000) (341)
- Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action (1992) (339)
- Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure. (2004) (338)
- The dark side of emotion: the addiction perspective (2015) (334)
- Neurobiology of Addiction: Toward the Development of New Therapies (2000) (331)
- Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats. (1996) (330)
- Corticotropin-releasing factor and neuropeptide y: role in emotional integration (1994) (328)
- mu-Opioid receptor knockout mice do not self-administer alcohol. (2000) (328)
- Addiction is a Reward Deficit and Stress Surfeit Disorder (2013) (323)
- Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration (1992) (320)
- Nucleus accumbens and amygdala are possible substrates for the aversive stimulus effects of opiate withdrawal (1990) (313)
- Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems (2004) (308)
- Individual differences in prefrontal cortex function and the transition from drug use to drug dependence (2010) (303)
- Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat. (1994) (301)
- Corticotropin Releasing Factor–Induced Amygdala Gamma-Aminobutyric Acid Release Plays a Key Role in Alcohol Dependence (2010) (300)
- Corticotropin-releasing factor and behavior. (1985) (299)
- Long-lasting increase in the set point for cocaine self-administration after escalation in rats (1999) (290)
- The Role of the Striatopallidal and Extended Amygdala Systems in Drug Addiction (1999) (289)
- The origin and distribution of dopamine-containing afferents to the rat frontal cortex (1978) (287)
- Corticotropin-Releasing Factor 1 Antagonists Selectively Reduce Ethanol Self-Administration in Ethanol-Dependent Rats (2007) (287)
- Neuroadaptive mechanisms of addiction: studies on the extended amygdala (2003) (284)
- Drug addiction: Pathways to the disease and pathophysiological perspectives (2007) (283)
- What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications. (2004) (283)
- Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis. (1994) (281)
- The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat (1987) (280)
- Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats (2012) (280)
- Alcohol self‐administration acutely stimulates the hypothalamic‐pituitary‐adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state (2008) (280)
- Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat (1995) (276)
- Mice Deficient for Both Corticotropin-Releasing Factor Receptor 1 (CRFR1) and CRFR2 Have an Impaired Stress Response and Display Sexually Dichotomous Anxiety-Like Behavior (2002) (270)
- Septal vasopressin modulates social memory in male rats (1988) (263)
- Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms (2008) (262)
- CRF antagonist reverses the “anxiogenic” response to ethanol withdrawal in the rat (2005) (261)
- Cocaine-but not food-seeking behavior is reinstated by stress after extinction (1997) (260)
- Genetic Differences in Response to Novelty and Spatial Memory Using a Two-Trial Recognition Task in Mice (2000) (259)
- The neural substrates for the motor-activating properties of psychostimulants: A review of recent findings (1986) (258)
- Selective disruption of displacement behaviour by lesions of the mesolimbic dopamine system (1980) (256)
- Conditioned Withdrawal Drives Heroin Consumption and Decreases Reward Sensitivity (2006) (255)
- Opponent process theory of motivation: Neurobiological evidence from studies of opiate dependence (1989) (252)
- Construct validity of a self-stimulation threshold paradigm: Effects of reward and performance manipulations (1992) (246)
- The role of CRF and CRF-related peptides in the dark side of addiction (2010) (244)
- Dynamics of neuronal circuits in addiction: reward, antireward, and emotional memory. (2009) (243)
- The role of corticotropin-releasing factor in behavioural responses to stress. (1993) (242)
- CRF–CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats (2007) (240)
- Negative reinforcement in drug addiction: the darkness within (2013) (239)
- Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1 1 Published on the World Wide Web on 27 November 1998. 1 (1999) (238)
- Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function (2005) (236)
- Alcohol dependence as a chronic pain disorder (2012) (235)
- Stress enhancement of craving during sobriety: a risk for relapse. (2005) (235)
- Corticotropin-releasing factor in the paraventricular nucleus modulates feeding induced by neuropeptide Y (1993) (232)
- Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. (2000) (227)
- A molecular link between the active component of marijuana and Alzheimer's disease pathology. (2006) (226)
- Animal models of psychiatric disorders. (2012) (225)
- The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat (1990) (225)
- Hyperactivity and hypoactivity produced by lesions to the mesolimbic dopamine system (1981) (224)
- Blockade of Nicotine Self-Administration with Nicotinic Antagonists in Rats (1999) (223)
- Corticotropin releasing factor (CRF) receptor antagonist blocks activating and ‘anxiogenic’ actions of CRF in the rat (1986) (222)
- Stress, Corticotropin‐releasing Factor, and Drug Addiction (1999) (220)
- The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABAA receptors (1997) (219)
- Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement (2020) (219)
- Hedonic valence, dopamine and motivation. (1996) (219)
- Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry (1987) (218)
- Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders (2016) (218)
- Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies (2012) (215)
- A role for GABA mechanisms in the motivational effects of alcohol. (2004) (212)
- Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. (2008) (211)
- The dark side of food addiction (2011) (210)
- Suppression of psychoactive effects of cocaine by active immunization (1995) (210)
- The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat (1993) (209)
- Cocaine reinforcement and extracellular dopamine overflow in rat nucleus accumbens: an in vivo microdialysis study (1989) (209)
- Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking (2012) (207)
- Depletion of dopamine in the caudate nucleus but not in nucleus accumbens impairs reaction-time performance in rats (1987) (203)
- The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats. (2007) (203)
- Corticotropin releasing factor: A key role in the neurobiology of addiction (2014) (201)
- Corticotropin-releasing factor antagonist attenuates the “anxiogenic-like” effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats (1999) (195)
- Escalation of methamphetamine self-administration in rats: a dose–effect function (2006) (191)
- Dopamine, addiction and reward (1992) (190)
- Preclinical studies of alcohol binge drinking (2011) (190)
- Heterogeneity of alcohol use disorder: understanding mechanisms to advance personalized treatment. (2015) (190)
- Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence. (2003) (189)
- Characterization of a novel and potent corticotropin-releasing factor antagonist in rats. (1994) (189)
- Opponent Process Model and Psychostimulant Addiction (1997) (185)
- The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat (1999) (182)
- Increased ethanol self-administration after a period of imposed ethanol deprivation in rats trained in a limited access paradigm. (1997) (182)
- Serotonin1B Receptor Stimulation Enhances Cocaine Reinforcement (1998) (182)
- Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens (2005) (181)
- CRF system recruitment mediates dark side of compulsive eating (2009) (179)
- Systemic κ‐opioid receptor antagonism by nor‐binaltorphimine reduces dependence‐induced excessive alcohol self‐administration in rats (2011) (178)
- Locomotor activation induced by infusion of endorphins into the ventral tegmental area: evidence for opiate-dopamine interactions. (1980) (178)
- Response artifact in the measurement of neuroleptic-induced anhedonia. (1981) (172)
- Lack of Self-Administration of Cocaine in Dopamine D1 Receptor Knock-Out Mice (2007) (171)
- Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior (2002) (170)
- Stress: Neurobiology and Neuroendocrinology (1990) (170)
- Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by alpha-helical CRF (9-41). (1989) (170)
- The therapeutic potential of CRF1 antagonists for anxiety (2004) (168)
- Neurocircuitry of alcohol addiction: synthesis from animal models. (2014) (166)
- The Role of CRF in Behavioral Aspects of Stress (1995) (166)
- Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance. (1999) (165)
- Chronic Acamprosate Eliminates the Alcohol Deprivation Effect While Having Limited Effects on Baseline Responding for Ethanol in Rats (1998) (164)
- D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat (1993) (164)
- Corticotropin-releasing factor potentiates acoustic startle in rats: Blockade by chlordiazepoxide (2004) (163)
- Increased Ethanol Self‐Administration in δ‐Opioid Receptor Knockout Mice (2001) (162)
- Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat (2002) (162)
- alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol. (2008) (160)
- Opioids, pain, the brain, and hyperkatifeia: a framework for the rational use of opioids for pain. (2010) (160)
- Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell (2013) (159)
- Dependence-induced increases in ethanol self-administration in mice are blocked by the CRF1 receptor antagonist antalarmin and by CRF1 receptor knockout (2007) (158)
- Vasopressor receptor antagonist prevents behavioural effects of vasopressin (1981) (157)
- The Functional Output of the Mesolimbic Dopamine System (1988) (156)
- Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals. (2015) (155)
- Anti-Stress Action of a Corticotropin-Releasing Factor Antagonist on Behavioral Reactivity to Stressors of Varying Type and Intensity (1994) (155)
- Monoamine Oxidase Inhibition Dramatically Increases the Motivation to Self-Administer Nicotine in Rats (2005) (155)
- Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: implications for the development of alcoholism (2004) (154)
- Allostasis and addiction: Role of the dopamine and corticotropin-releasing factor systems (2012) (153)
- Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system. (1993) (153)
- Effects of corticotropin releasing factor on locomotor activity in hypophysectomized rats (1985) (153)
- Time-dependent quantifiable withdrawal from ethanol in the rat: effect of method of dependence induction. (1996) (153)
- Neurochemical Correlates of Cocaine and Ethanol Self‐Administration a (1992) (153)
- Activating and 'anxiogenic' effects of corticotropin releasing factor are not inhibited by blockade of the pituitary-adrenal system with dexamethasone. (1986) (152)
- Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats (2005) (152)
- Cocaine vaccines: antibody protection against relapse in a rat model. (2000) (152)
- Narcolepsy and its treatment with stimulants. ASDA standards of practice. (1994) (151)
- Progress in corticotropin-releasing factor-1 antagonist development. (2010) (151)
- Effects of mesolimbic dopamine depletion on responding maintained by cocaine and food. (1994) (151)
- Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction (2006) (151)
- Vapor Inhalation of Alcohol in Rats (2008) (150)
- Development of pharmacotherapies for drug addiction: a Rosetta Stone approach (2009) (150)
- Corticotropin-releasing factor antagonist blocks stress-induced fighting in rats (1987) (150)
- Extended Access to Cocaine Self-Administration Produces Long-Lasting Prefrontal Cortex-Dependent Working Memory Impairments (2008) (150)
- Destruction of the locus coeruleus decreases physical signs of opiate withdrawal (1993) (149)
- CB1 cannabinoid receptor antagonist‐induced opiate withdrawal in morphine‐dependent rats (1998) (149)
- Genetical genomic determinants of alcohol consumption in rats and humans (2009) (148)
- Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide (2002) (145)
- Opioid use disorder (2020) (143)
- Addiction and stress: An allostatic view (2019) (141)
- Neurobiology of dysregulated motivational systems in drug addiction. (2010) (141)
- Can aversive properties of (peripherally-injected) vasopressin account for its putative role in memory? (1983) (140)
- Interleukin-2 (IL-2) induces corticotropin-releasing factor (CRF) release from the amygdala and involves a nitric oxide-mediated signaling; comparison with the hypothalamic response. (1995) (140)
- Animal models of craving for ethanol. (2000) (139)
- D3 receptor test in vitro predicts decreased cocaine self‐administration in rats (1997) (139)
- The behavioural effects of enkephalin analogues injected into the ventral tegmental area and globus pallidus (1981) (138)
- Buprenorphine and a CRF1 Antagonist Block the Acquisition of Opiate Withdrawal-Induced Conditioned Place Aversion in Rats (2005) (138)
- α1-Noradrenergic system role in increased motivation for cocaine intake in rats with prolonged access (2008) (138)
- Measuring meals: structure of prandial food and water intake of rats. (2005) (138)
- Locus coeruleus lesions and learning in the rat (1976) (138)
- Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activation. (2004) (137)
- Central administration of an opiate antagonist decreases oral ethanol self-administration in rats. (1999) (137)
- Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist (2003) (136)
- Corticotropin releasing factor, stress and behavior (1994) (135)
- Sex, strain, and estrous cycle influences on alcohol drinking in rats (2017) (134)
- Centrally injected arginine vasopressin (AVP) facilitates social memory in rats (1987) (133)
- Two discrete nucleus accumbens projection areas differentially mediate cocaine self-administration in the rat (1993) (133)
- Prolonged tolerance, dependence and abstinence following subcutaneous morphine pellet implantation in the rat. (1994) (132)
- The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat (1998) (131)
- Stimulation of food intake in rats by centrally administered hypothalamic growth hormone-releasing factor (1985) (129)
- Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. (2010) (128)
- Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: Alleviation by CRF1 receptor antagonism (2012) (128)
- The addicted brain craves new neurons: putative role for adult-born progenitors in promoting recovery (2012) (128)
- An observational method for quantifying the behavioural effects of dopamine agonists: Contrasting effects of d-Amphetamine and apomorphine (2004) (128)
- Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats. (1993) (127)
- Nucleus accumbens NMDA antagonist decreases locomotor activity produced by cocaine, heroin or accumbens dopamine, but not caffeine (1991) (127)
- Precipitation of morphine withdrawal syndrome in rats by administration of mu-, delta- and kappa-selective opioid antagonists (1992) (125)
- Methamphetamine Self-Administration and Voluntary Exercise Have Opposing Effects on Medial Prefrontal Cortex Gliogenesis (2007) (124)
- NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat (1992) (124)
- Nibbling at CRF receptor control of feeding and gastrocolonic motility. (2003) (124)
- Opiate Withdrawal-Induced Fos Immunoreactivity in the Rat Extended Amygdala Parallels the Development of Conditioned Place Aversion (2001) (121)
- CRF1 receptor antagonists attenuate escalated cocaine self-administration in rats (2008) (121)
- Amphetamine disruption of prepulse inhibition of acoustic startle is reversed by depletion of mesolimbic dopamine (2005) (120)
- REVIEW: Alcohol‐related genes: contributions from studies with genetically engineered mice (2006) (120)
- Cocaine abuse and dependence. (1995) (120)
- The role of mesolimbic dopamine in conditioned locomotion produced by amphetamine. (1988) (119)
- Neuropharmacology of cocaine and ethanol dependence. (1992) (119)
- Extended Access to Nicotine Self-Administration Leads to Dependence: Circadian Measures, Withdrawal Measures, and Extinction Behavior in Rats (2007) (119)
- Escalation of drug self-administration as a hallmark of persistent addiction liability (2013) (119)
- Neuroleptic-like distruption of the conditioned avoidance response requires destruction of both the mesolimbic and nigrostriatal dopamine systems (1984) (118)
- A second-generation vaccine protects against the psychoactive effects of cocaine. (2001) (117)
- Substantia innominata: Critical link in the behavioral expression of mesolimbic dopamine stimulation in the rat (1984) (116)
- Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats. (1988) (115)
- Aversive properties of opiate receptor blockade: evidence for exclusively central mediation in naive and morphine-dependent rats (1988) (115)
- Cellular and Behavioral Interactions of Gabapentin with Alcohol Dependence (2008) (115)
- Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat. (1984) (115)
- Central administration of a CRF antagonist blocks the development of stress-induced behavioral sensitization (1990) (115)
- Operant behavior and alcohol levels in blood and brain of alcohol-dependent rats. (2009) (115)
- Effects of d-amphetamine and apomorphine upon operant behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens. (1983) (115)
- Brain disease model of addiction: why is it so controversial? (2015) (114)
- Propranolol antagonizes the enhanced conditioned fear produced by corticotropin releasing factor. (1988) (114)
- Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels (2003) (113)
- Estrous cycle effects on operant responding for ethanol in female rats. (1998) (112)
- Varied Access to Intravenous Methamphetamine Self-Administration Differentially Alters Adult Hippocampal Neurogenesis (2008) (112)
- Locus coeruleus lesions: Learning and extinction (1978) (111)
- Compulsive-Like Responding for Opioid Analgesics in Rats with Extended Access (2015) (111)
- Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction. (2005) (111)
- Inhibition of kappa opioid receptors attenuated increased cocaine intake in rats with extended access to cocaine (2009) (111)
- Dopamine receptor agonists, partial agonists and psychostimulant addiction. (1994) (110)
- The transition from controlled to compulsive drug use is associated with a loss of sensitization (2004) (110)
- Pituitary-adrenal axis responses to acute amphetamine in the rat (1993) (109)
- Genetic studies of alcohol dependence in the context of the addiction cycle (2017) (109)
- Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers. (1999) (108)
- Effects of Naltrexone Alone and In Combination With Acamprosate on the Alcohol Deprivation Effect in Rats (2003) (108)
- Stress modulation of drug self-administration: Implications for addiction comorbidity with post-traumatic stress disorder (2012) (107)
- Alcohol, the reward system and dependence. (1994) (107)
- Dynorphin, Dysphoria, and Dependence: the Stress of Addiction (2016) (105)
- A Role for the Endocannabinoid System in the Increased Motivation for Cocaine in Extended-Access Conditions (2009) (105)
- Traumatic stress reactivity promotes excessive alcohol drinking and alters the balance of prefrontal cortex-amygdala activity (2013) (105)
- Biomarkers in substance use disorders. (2015) (105)
- Effects of CRF1-receptor and opioid-receptor antagonists on dependence-induced increases in alcohol drinking by alcohol-preferring (P) rats. (2008) (104)
- Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats (2006) (104)
- Anxiogenic-Like Effects of Spontaneous and Naloxone-Precipitated Opiate Withdrawal in the Elevated Plus-Maze (1998) (104)
- A vaccine strategy that induces protective immunity against heroin. (2011) (103)
- Behavioral implications of dopaminergic neurons in the mesolimbic system. (1977) (102)
- Long-Term Antagonism of κ Opioid Receptors Prevents Escalation of and Increased Motivation for Heroin Intake (2013) (102)
- Dissociation of Locomotor Activation and Suppression of Food Intake Induced by CRF in CRFR1-Deficient Mice. (2000) (102)
- Endogenous corticotropin-releasing factor modulates feeding induced by neuropeptide Y or a tail-pinch stressor (1992) (102)
- Neuropeptide Y Opposes Alcohol Effects on Gamma-Aminobutyric Acid Release in Amygdala and Blocks the Transition to Alcohol Dependence (2011) (102)
- Neuropeptide Y blocks anxiogenic-like behavioral action of corticotropin-releasing factor in an operant conflict test and elevated plus maze (2000) (101)
- The dopamine receptor agonist 7-OH-DPAT modulates the acquisition and expression of morphine-induced place preference. (1995) (101)
- Paradoxical reinforcing properties of apomorphine: Effects of nucleus accumbens and area postrema lesions (1983) (100)
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- Serotonin1B receptor stimulation enhances dopamine-mediated reinforcement (1996) (81)
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- Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats (2017) (66)
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- Reinforcement processes in opiate addiction: A homeostatic model (1996) (64)
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- Mineralocorticoid and glucocorticoid receptor antagonists in animal models of anxiety (1996) (64)
- Changes in response to a dopamine receptor antagonist in rats with escalating cocaine intake (2004) (64)
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- Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity (2004) (57)
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- RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist (1999) (57)
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- INTERFERON-α AND TRANSFORMING GROWTH FACTOR-β1 REGULATE CORTICOTROPIN-RELEASING FACTOR RELEASE FROM THE AMYGDALA: COMPARISON WITH THE HYPOTHALAMIC RESPONSE* * This work was supported by the NIMH AIDS Center, Grant MH 47680, and the Schumacher-Kramer Foundation. (1997) (53)
- Rapid Induction of Conditioned Opiate Withdrawal in the Rat (1993) (53)
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- Both conditioned taste preference and aversion induced by corticotropin-releasing factor (1991) (50)
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- Characterization of the effects of the partial dopamine agonist terguride on cocaine self-administration in the rat. (1998) (49)
- Kappa opioid control of seizures produced by a virus in an animal model. (2006) (49)
- PRECLINICAL STUDY: FULL ARTICLE: The dopamine D3 receptor partial agonist CJB090 and antagonist PG01037 decrease progressive ratio responding for methamphetamine in rats with extended‐access (2010) (49)
- The NK1 Receptor Antagonist L822429 Reduces Heroin Reinforcement (2013) (48)
- Pregnane steroid alphaxalone attenuates anxiogenic behavioral effects of corticotropin releasing factor and stress (1992) (48)
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- Impulsivity Derived From the Dark Side: Neurocircuits That Contribute to Negative Urgency (2019) (48)
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- Adenovirus Capsid-Based Anti-Cocaine Vaccine Prevents Cocaine from Binding to the Nonhuman Primate CNS Dopamine Transporter (2013) (48)
- Time-Dependent Alterations in ICSS Thresholds Associated With Repeated Amphetamine Administrations (2000) (47)
- A Combination of Buprenorphine and Naltrexone Blocks Compulsive Cocaine Intake in Rodents Without Producing Dependence (2012) (47)
- Methylnaloxonium diffuses out of the rat brain more slowly than naloxone after direct intracerebral injection (1991) (46)
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- Fate of systemically administered cocaine in nonhuman primates treated with the dAd5GNE anticocaine vaccine. (2014) (46)
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- Structural and compositional determinants of cortistatin activity (1999) (46)
- Animal Models of Drug Addiction (2006) (45)
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- Effects of naloxone on the anticonflict properties of alcohol and chlordiazepoxide. (1980) (45)
- Urocortin shares the memory modulating effects of corticotropin-releasing factor (CRF): mediation by CRF1 receptors (2002) (45)
- Alcohol reverses the proconflict effect of corticotropin-releasing factor (1986) (44)
- A dopamine partial agonist and antagonist block amphetamine self-administration in a progressive ratio schedule (2001) (44)
- Prefrontal cortex dysfunction in borna disease virus (BDV)-infected rats (1996) (44)
- Role of neuropeptides in learning versus performance: Focus on vasopressin (1989) (44)
- Stress, Corticotropin-Releasing Factor, and Behavior (1985) (44)
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- AAVrh.10-mediated expression of an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced behavior. (2012) (43)
- The sequenced rat brain transcriptome – its use in identifying networks predisposing alcohol consumption (2015) (43)
- Tardive dyskinetic syndrome in rats infected with Borna disease virus (1994) (43)
- Methysergide potentiates the hyperactivity produced by MDMA in rats (1988) (43)
- Refractory dependence on opioid analgesics. (2019) (42)
- Osmotic stress mimics effects of vasopressin on learned behaviour (1985) (42)
- PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease (2019) (42)
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- Epilepsy, CNS viral injury and dynorphin. (2004) (42)
- Rewarding properties of beta-endorphin as measured by conditioned place preference. (1987) (42)
- Conditioned facilitation of brain reward function after repeated cocaine administration. (2003) (42)
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- The corticotropin-releasing factor/urocortin system and alcohol. (2002) (41)
- Clonidine Blocks Acquisition But not Expression of Conditioned Opiate Withdrawal in Rats (1998) (41)
- Differences in one-way active avoidance learning in mice of three inbred strains (1992) (41)
- Phosphodiesterase 10A Regulates Alcohol and Saccharin Self-Administration in Rats (2014) (41)
- Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks (2015) (41)
- Neuroscience of Compulsive Eating Behavior (2017) (41)
- BK channel β1 and β4 auxiliary subunits exert opposite influences on escalated ethanol drinking in dependent mice (2013) (40)
- Lisuride Reduces Psychomotor Retardation during Withdrawal from Chronic Intravenous Amphetamine Self-Administration in Rats (1993) (40)
- Disruption of the CRF2 Receptor Pathway Decreases the Somatic Expression of Opiate Withdrawal (2008) (39)
- Effects of intracerebroventricular administration of methyl naloxonium chloride on heroin self-administration in the rat (1985) (39)
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- Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication (2021) (39)
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- MDMA produces stimulant-like conditioned locomotor activity (2004) (38)
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- Converging Structural and Functional Evidence for a Rat Salience Network (2020) (38)
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- ‘Catatonia’ produced by alfentanil is reversed by methylnaloxonium microinjections into the brain (1986) (37)
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- Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the rat (2004) (36)
- Neuropeptide Y Y2R blockade in the central amygdala reduces anxiety‐like behavior but not alcohol drinking in alcohol‐dependent rats (2014) (36)
- Exposure to chronic intermittent nicotine vapor induces nicotine dependence (2010) (36)
- Addictions NeuroImaging Assessment (ANIA): Towards an integrative framework for alcohol use disorder (2020) (36)
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- Dorsal pallidum as a functional motor output of the corpus striatum (1989) (35)
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- Acutely administered ethanol participates in testosterone synthesis and increases testosterone in rat brain. (2003) (35)
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- Compulsive-Like Sufentanil Vapor Self-Administration in Rats (2018) (35)
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- Anxiolytic-Like Effects of Antisauvagine-30 in Mice Are Not Mediated by CRF2 Receptors (2013) (19)
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- Erratum: Resistance to diet-induced obesity in μ-opioid receptor-deficient mice: Evidence for a "thrifty gene" (Diabetes (February 2005) 54, (3510-3516)) (2006) (16)
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- Cocaine antagonizes anxiolytic effects of ethanol (2004) (16)
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- CHAPTER 1 – What is Addiction? (2006) (11)
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- Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a Crhr1 Promoter Polymorphism (2018) (10)
- Conditioned Opioid Withdrawal Decreases Nociceptin/Orphanin FQ Levels in the Frontal Cortex and Olfactory Tubercle (2002) (10)
- The Role of Endorphins in Neurobiology, Behavior, and Psychiatric Disorders (1984) (10)
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- Lisuride reduces intravenous cocaine self-administration in rats (1994) (9)
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- Endogenous opiates and fasting. (1981) (9)
- Ethanol effects on delayed spatial matching as modeled by a negative exponential forgetting function (2005) (9)
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- It Is Time to Take a Stand for Medical Research and Against Terrorism Targeting Medical Scientists (2008) (9)
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- Key role for enkephalinergic tone in cortico–striatal–thalamic function (2002) (8)
- Learning and Memory in Addiction (2017) (8)
- Cerebral glucose metabolism during opioid withdrawal following methylnaloxonium injection into the locus coeruleus (1998) (8)
- Pathophysiology of Addiction (2015) (8)
- Post-ictal locomotor activity in three different rat models of epilepsy (1982) (7)
- Reinforcement pathways for cocaine. (1988) (7)
- κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats (2021) (7)
- Regarding “Dynorphin is a downstream effector of striatal BDNF regulation of ethanol intake” (2008) (7)
- Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving FosB and Calcium / Calmodulin-Dependent Protein Kinase II in the Citation (2013) (7)
- The dark side of compulsive eating and food addiction (2019) (7)
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- Activators of potassium M currents have anticonvulsant actions in two rat models of encephalitis. (2007) (6)
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- Nutritional Ketosis as a Potential Treatment for Alcohol Use Disorder (2021) (5)
- Orofacial dyskinesias and dystonia in rats infected with Borna disease virus; a model for tardive dyskinetic syndromes (1999) (5)
- Reply to: Neuroclinical Assessment of Addiction Needs to Incorporate Decision-Making Measures and Ecological Validity (2017) (5)
- EFFECTS OF ADENOSINE A2 RECEPTOR‐SELECTIVE DRUGS ON BRAIN STIMULATION REWARD THRESHOLDS IN THE RAT (1998) (5)
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- Neurobiological theories of addiction (2019) (4)
- m-Opioid Receptor Knockout Mice Do Not Self-Administer Alcohol 1 , 2 (2000) (4)
- Erratum to: Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function (2011) (4)
- Psychostimulant properties of MDMA. (1989) (4)
- Application of Experimental Stressors in Laboratory Rodents (1997) (4)
- CHAPTER 6 – Nicotine (2006) (4)
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- What Is Pleasure? (2010) (3)
- Introduction to the Neuropsychopharmacology of Drug Addiction (2015) (3)
- EEG effects of subcutaneous and intracerebroventricular injections of arginine vasopressin in the rat (2004) (3)
- An Examination of Child and Adolescent Neurodevelopment Through National Institutes of Health Studies (2020) (3)
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- Hypocretin and Brain Reward Function (2005) (3)
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- Frameworks of Alcohol Addiction: Alcohol Addiction as a Reward Deficit and Stress Surfeit Disorder (2014) (3)
- Pancreatic Pain—Knowledge Gaps and Research Opportunities in Children and Adults (2021) (3)
- Alcohol Use Disorders: Tracts, Twins, and Trajectories (2015) (3)
- Corticosteroid sensitization drives opioid addiction (2022) (3)
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- MODIFICATION IN THE DEVELOPMENT OF MORPHINE DEPENDENCE IN RATS BY ELECTROLYTIC LESIONS OF THE LOCUS COERULEUS (1992) (2)
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- The Role of Animal Models in Reward Deficit Disorders: Views from Academia (2008) (2)
- Preface (New Research Frontiers and Advances in Drug Addiction) (2011) (2)
- Remembering Mary Jeanne Kreek and her many contributions to addiction science (2021) (2)
- The Mesocorticolimbic Circuit in Drug Dependence and Reward — a Role for the Extended Amygdala? (2019) (2)
- Toward a unified neuropsychiatric hypothesis (1987) (2)
- Corrigendum: Impulsivity Derived From the Dark Side: Neurocircuits That Contribute to Negative Urgency (2019) (2)
- CHAPTER 3 – Psychostimulants (2006) (2)
- Dissecting compulsive eating behavior into three elements (2019) (2)
- A Basolateral Amygdala Microcircuit for Drug Craving: Is There a Craving Engram? (2021) (2)
- Antibody-catalyzed oxidation of delta(9)-tetrahydrocannabinol. (2007) (2)
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- Alcohol and Aging - An Area of Increasing Concern. (2022) (2)
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- Knockdown of Hypocretin/Orexin Attenuates Extended-Access Cocaine Self-Administration in Rats (2017) (1)
- Dopamine D1 and μ-opioid receptor antagonism blocks anticipatory 50 kHz ultrasonic vocalizations induced by palatable food cues in Wistar rats (2013) (1)
- Learning and memory principles and findings with a focus on vasopressin (1987) (1)
- RO 15-4513 antagonizes barbiturate but not halothane anesthesia (1988) (1)
- Hypocretin regulates brain reward function and cocaine consumption in rats (2003) (1)
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- SY07-3MEDICATIONS FOR TREATMENT OF ALCOHOLISM THAT DERIVE FROM THE DARK SIDE OF ADDICTION (2014) (1)
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- Optogenetic characterization of corticotropin-releasing factor pathways in the central nucleus of the amygdala in alcohol dependence (2017) (1)
- The Role of Dopamine in the Motivational Vulnerability to Addiction (2009) (1)
- PL1ADDICTION AS A REWARD, STRESS AND EXECUTIVE FUNCTION DISORDER (2014) (1)
- Neurobiological Mechanisms of Drug Addiction (2013) (1)
- Overview of addiction and the brain (2020) (1)
- Cocaine's long run (2004) (1)
- Bases neurológicas de la adicción a la adicción a la cocaína (1996) (1)
- THE EXTENDED AMYGDALA AND THE CAUDOMEDIAL SHELL OF THE ACCUMBENS; AN ???EMOTIONAL-MOTOR??? INTERFACE (1996) (1)
- Inaugural issue of the journal of addiction medicine. (2007) (1)
- Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice. (2000) (1)
- ELECTRON MICROSCOPIC LOCALIZATION OF TETRAHYDROPAPAVEROLINE IN THE RAT CAUDATE NUCLEUS (1979) (1)
- Neurocircuitry of Addiction: A brain reward deficit, stress surfeit and executive function disorder (2013) (1)
- Central amygdala CRF pathways in alcohol dependence (2017) (1)
- Catecholamines II (1989) (1)
- CHAPTER 7 – Cannabinoids (2006) (1)
- Neuroanatomy of Addiction (2012) (1)
- The role of the Periaqueductal Gray Area in maladaptive emotional and behavioral responses stemming from alcohol dependence (2017) (1)
- Understanding Hyperkatifeia to Inform Treatment for Alcohol Use Disorder: An Assessment of the National Institute on Alcohol Abuse and Alcoholism Research Portfolio (2022) (1)
- Neurobiologic Advances from the Brain Disease Model of Addiction (2022) (1)
- Addiction: Neurobiological Mechanism (2009) (1)
- FURTHER ELUCIDATION OF BRAIN SITES WHICH MEDIATE ALFENTANIL - INDUCED MUSCLE RIGIDITY IN THE RAT (1988) (1)
- Animal models of addictive disorders (1999) (1)
- Straight talk with...George Koob (2014) (1)
- Stress, negative reinforcement and compulsive drug seeking (2017) (1)
- Origin of dopaminergic afferents to the rat frontal cortex [proceedings]. (1977) (1)
- Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats (2014) (1)
- Editorial Board (2005) (0)
- A dysphoric-like state during early withdrawal from extended access to methamphetamine self-administration in rats (2012) (0)
- Vulnerability to substance abuse: A consideration of allostatic loading factors (2021) (0)
- Negative reinforcement via motivational withdrawal is the driving force behind the transition to addiction (2014) (0)
- THE ROLE OF THE MESOLIMBIC DOPAMINE SYSTEM IN LOCOMOTOR ACTIVITY, EATING AND DRINKING IN THE RAT (1979) (0)
- The Role of Opiate Withdrawal in Addiction (1996) (0)
- First Congress of "Alcoholism and stress: a framework for future treatment strategies": Introduction to the proceeding. (2009) (0)
- Opiate dependence induces cell type-specific plasticity of intrinsic membrane properties in the rat juxtacapsular bed nucleus of stria terminalis (jcBNST) (2017) (0)
- Neurophysiology of Opiate Dependence (1996) (0)
- Pharmacology, Biochemistry and Behavior (2010) (0)
- S.03.05 Hypocretin/orexin in addiction: a mediator of stress-induced reinstatement of cocaine-seeking behaviour (2008) (0)
- THE FUTURE OF DRUG ABUSE RESEARCH (1998) (0)
- LISURIDE REDUCES PSYCHOSTIMULANT SELF‐ADMINISTRATION AND WITHDRAWAL IN RATS (1992) (0)
- How Alcohol Misuse Fans the Pandemic and the Pandemic Exacerbates Alcohol Misuse (2020) (0)
- Chapter 4 – Psychostimulants (2014) (0)
- CRF 1 antagonists in animal models of anxiety , depression and addictive disorders (2010) (0)
- The neurobiology of drug dependence: Evidence for an opponent process (1991) (0)
- S.02.02 Involvement of corticotropin-releasing factor in addiction (1996) (0)
- Erratum: Hypertonic saline mimics the effects of vasopressin on social recognition in rats (Behavioural Pharmacology 2, 513-516 (1992)) (1992) (0)
- Finding our niche (2006) (0)
- Non Print Items Author and Co-author Contact Information (2017) (0)
- Comprar Handbook of Neurochemistry and Molecular Neurobiology · Drugs and the Nervous System | Parsons, Loren | 9780387303673 | Springer (2009) (0)
- Stimulant Drugs: Psychostimulants and Addiction (2016) (0)
- Larry Parsons: Researcher, mentor, and friend (2018) (0)
- Behavioral and neurochemical alterations induced bY hYP oxia in rats (2003) (0)
- Poster Session III (1992) (0)
- Drug addiction. (2000) (0)
- Mechanisms of neuropeptide actions on behavior (1986) (0)
- Editorial (1995) (0)
- Self-administration of drugs of abuse in rats: Nucleus accumbens glutamate modulates mesolimbic dopamine function (1990) (0)
- Addiction: Reward, motivation and stress (2006) (0)
- Chapter 8 – Cannabinoids (2014) (0)
- Treatment of Opiate Withdrawal (1996) (0)
- Wake-Promoting Substances (2013) (0)
- Tail-pinch and T-maze learning by rats (1977) (0)
- On the critical need to investigate the effect of alcohol in the older population. (2022) (0)
- NIAAA 50th Anniversary Festschrift: From the Editor (2022) (0)
- Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats (2012) (0)
- LOCALIZATION OF BRAIN SITES WHICH MAY PLAY A ROLE IN ALFENTANIL-INDUCED MUSCLE RIGIDITY IN THE RAT (1987) (0)
- Continuing the conversation around opioid use disorder and post-traumatic stress disorder comorbidity. (2022) (0)
- Medications for the Treatment of Addiction – A Neurobiological Perspective (2015) (0)
- George F. Koob (2022) (0)
- Drug Addiction: Transition from Neuroadaptation to Pathophysiology (2006) (0)
- Erratum to: Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function (2011) (0)
- The Dark Side of Addiction: Dysregulated Neuroadaptation of Emotional Neurocircuits (2013) (0)
- Review for "The anterior insular cortex in the rat exerts an inhibitory influence over the loss of control of heroin intake and subsequent propensity to relapse" (2020) (0)
- Psychostimulants and Addiction (2013) (0)
- Neuroleptics: Breaking the Dopamine Circle. (1984) (0)
- The NIH Blueprint for Neuroscience Research Seeks Community Input on Future Neuroscience Investments (2019) (0)
- B63 EXTRACELLULAR CRF LEVELS IN THE CENTRAL NUCLEUS OF THE AMYGDALA AND ANXIETY-LIKE BEHAVIOR DURING NICOTINE WITHDRAWAL (2005) (0)
- Drug Withdrawal – Motivational View (2010) (0)
- Extended access nicotine self-administration with periodic deprivation increases immature neurons in the hippocampus (2014) (0)
- Prefrontal Cortex Dysfunction Virus ( BDV )-Infected Rats in Borna Disease (2004) (0)
- A116 AKEYROLE FORHYPOCRETIN INREGULATINGBRAIN REWARDFUNCTIONANDREINSTATEMENT FORDRUG- (2005) (0)
- TREATMENT OF DEPRESSION IN ELDERLY PATIENTS-CLASSICAL VS. NOVEL ANTIDEPRESSANTS (1996) (0)
- Effects of Alcohol Withdrawal on Sleep Macroarchitecture and Microarchitecture in Female and Male Rats (2022) (0)
- CHARACTERIZATION OF CORTICOTROPIN AND GROWTH HORMONE RELEASING FACTOR. (1983) (0)
- Neurochemistry of Opiate Dependence (1996) (0)
- Drug Withdrawal (2020) (0)
- Extended access to fentanyl vapor self-administration leads to addiction-like behaviors in mice: Blood chemokine/cytokine levels as potential biomarkers (2022) (0)
- 4.27 Learning and Memory in Addiction (2019) (0)
- Inactivation With Muscimol Working Memory in Monkeys Examined by Local Prefrontal Cortical Representation of Visuospatial (2015) (0)
- onoamine Oxidase Inhibition Dramatically rolongs the Duration of Nicotine Withdrawal-Induce lace Aversion (2007) (0)
- COCAINE-INDUCED EFFECTS ON MALE RAT SEXUAL BEHAVIOUR AND STRETCHING-YAWNING (1996) (0)
- Measurement and Function of Neuropeptides (1989) (0)
- A distributed CRF network in rat extended amygdala regulates anxiety and excessive alcohol drinking (2017) (0)
- Chronic Stress and Neuronal Pathology : Neurochemical , Molecular and Genetic Factors 6 (0)
- PREFACE (2011) (0)
- Neurofunctional Domains Derived from Deep Behavioral Phenotyping in Alcohol Addiction (2019) (0)
- Reply to Brewer: Liver-targeted ALDH2 inhibition may reduce alcohol-seeking behaviors with limited side effects (2020) (0)
- Moal processes in addiction Neurobiological mechanisms for opponent motivational (2008) (0)
- Neuropharmacology. Psychoactive smoke. (1996) (0)
- Selective blockade of 2-arachidonoylglycerol hydrolysis affects learning and memory performance while slowing down epileptogenesis in rodents (2014) (0)
- Erratum: Unlimited Access to Heroin Self-Administration: Independent Motivational Markers of Opiate Dependence (2006) (0)
- In Memoriam Martin Adler, Ph.D (2022) (0)
- RESPONSE TO “ ANXIOUS TO DRINK : GABAPENTIN NORMALIZES GABAERGIC TRANSMISSION IN THE CENTRAL AMYGDALA AND REDUCES SYMTPOMS OF ETHANOL DEPENDENCE (2008) (0)
- Molecular Knockout Approach to the Study of Brain Dopamine Function (2002) (0)
- Corticotropin Releasing Factor/Urocortin Network of Ligands and Their Receptors (2008) (0)
- 208. Corticotropin releasing factor, stress and allostasis (2000) (0)
- VIEW ON DRUG DISCRIMINATION: THE GOOD,THE BAD ANDTHE ULTIMATE (1998) (0)
- ALFENTANIL-INDUCED RIGIDITY IN THE RAT: THE ROLE OF THE NUCLEUS RAPHE PONTIS AND THE CAUDATE NUCLEUS (1985) (0)
- Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats (2019) (0)
- NIH Appoints Director of the NIAAA (2014) (0)
- ADDICTION AS A REWARD, STRESS AND EXECUTIVE FUNCTION DISORDER (2015) (0)
- MOLECULAR BIOLOGY OF STRESS Sponsored by: The Director's Sponsors Fund (1988) (0)
- What can science contribute to the treatment of alcoholism?: (526232014-001) (2013) (0)
- Chronic cocaine exposure causes reduced blood flow and vasoconstriction in mouse prefrontal cortex in vivo (2020) (0)
- Reply to Cohen and Murnion. (2020) (0)
- Motivating Change in Addiction via Modulation of the Dark Side (2018) (0)
- Neurobehavioral serendipity in sheep's clothing. (1988) (0)
- Pursuing the Mechanisms Underlying Alcohol-Induced Changes in the Ghrelin System: New Insights from Preclinical and Clinical Investigations (2020) (0)
- SU58 EPIGENOME-WIDE ASSOCIATION ANALYSIS AND REPLICATION IMPLICATES DEREGULATION OF PCSK9 IN ALCOHOL USE DISORDER (2019) (0)
- Editorial (1995) (0)
- CHAPTER 8 – Imaging (2006) (0)
- 211. Role of the Central Nucleus of the Amygdala in the Dark Side of Drug Addiction: A Neuroendocrine Connection (2019) (0)
- MOTIVATIONAL MEASURES OF DRUG DEPENDENCE (1992) (0)
- a116 A Key Role For Hypocretin In Regulating Brain Reward Function And Reinstatement For Drug-seeking Behavior In Rats (2005) (0)
- Antireward, compulsivity, and addiction: seminal contributions of Dr. Athina Markou to motivational dysregulation in addiction (2017) (0)
- Samidorphan, an opioid receptor antagonist, attenuates drug-induced increases in extracellular dopamine concentrations and drug self-administration in male Wistar rats (2021) (0)
- Running title: The role of 5-HT1A autoreceptors in cocaine addiction (2015) (0)
- 2013 Daniel H. Efron Research Award (2012) (0)
- CHAPTER 4 – Opioids (2006) (0)
- The Search for Theory in Psychopharmacology. (1983) (0)
- Comprar Frontiers in the Neurobiology of Addiction | Cynthia M. Kuhn | 9780849373916 | Informa Healthcare (2008) (0)
- Identifying candidate drivers of alcohol dependence-induced excessive drinking by assembly and interrogation of brain-specific regulatory networks (2015) (0)
- Preface to Addiction Reviews 2 (2010) (0)
- A new study challenges the idea that the ventromedial prefrontal cortex inhibits drug relapse, by selectively inactivating a subpopulation of neurons in this brain area and showing attenuation of context-induced reinstatement of heroin seeking. (2011) (0)
- Neurohormonal Systems Underlying Drug Addiction: Relevance for Treatment Strategies (1995) (0)
- Learning and Memory: Genetics (1999) (0)
- Heroin- and Fentanyl-Induced Respiratory Depression in a Rat Plethysmography Model: Potency, Tolerance, and Sex Differences (2023) (0)
- Chronic Stress and Neuropathology: Neurochemical, Molecular, and Genetic Factors (2005) (0)
- Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects (2018) (0)
- Larry Stein: pioneer neuropsychopharmacology researcher, mentor, and friend (2019) (0)
- Works Title Genetical genomic determinants of alcohol consumption in rats and humans (2009) (0)
- Substance Use Disorders Among Forcibly Displaced People: a Narrative Review (2023) (0)
- Animal models of addiction (2019) (0)
- NIAAA-Supported Research and the Public Discourse Around Alcohol: A Clarification Regarding Mitchell and McCambridge (2023). (2023) (0)
- Endogenous serotonin system does not participate in the withdrawal opiate, but its inhibition by stimulation 5-HT1A receptor increases the effectiveness of the clonidine in rats / El sistema endógeno de serotonina no participa en la abstinencia opiácea... (2003) (0)
- Alcoholism, CRF and Molecular Genetic Allostasis (2008) (0)
- Potentiation of brain reward mechanisms by psychomotor stimulant drugs (1977) (0)
- Neurobiological Substrates Mediating the Reinforcing Effects of Psychomotor Stimulant and Opiate Drugs (2017) (0)
- Behavioral, pharmacologic and neurobiologic variables important to the analysis of drug self-administration: implications for the discovery of potential pharmacotherapies. (1994) (0)
- Editorial Board (2013) (0)
- Initial pharmacological characterization of a major hydroxy metabolite of PF-5190457: inverse agonist activity of PF-6870961 at the ghrelin receptor. (2023) (0)
- George et al. 2012 Supplementary (2015) (0)
- Neural Substrates for Sensitization and Counteradaptation sf Reward (1997) (0)
- AVP release by acetylcholine or norepinephrine Region-specific and cytokine-specific regulation (1995) (0)
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What Schools Are Affiliated With Georges F. Koob?
Georges F. Koob is affiliated with the following schools:
