George K. Aghajanian
#83,872
Most Influential Person Now
George K. Aghajanian's AcademicInfluence.com Rankings
George K. Aghajanianphilosophy Degrees
Philosophy
#2981
World Rank
#4922
Historical Rank
Logic
#885
World Rank
#1451
Historical Rank
George K. Aghajanianbiology Degrees
Biology
#3554
World Rank
#5418
Historical Rank
Neuroscience
#338
World Rank
#354
Historical Rank
Download Badge
Philosophy Biology
Why Is George K. Aghajanian Influential?
(Suggest an Edit or Addition)George K. Aghajanian's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists (2010) (2306)
- Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity. (1973) (1288)
- Synaptic Dysfunction in Depression: Potential Therapeutic Targets (2012) (1078)
- Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. (1990) (964)
- Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants (2016) (941)
- Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure (2011) (916)
- Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine (1975) (896)
- Electrophysiological responses of serotoninergic dorsal raphe neurons to 5‐HT1A and 5‐HT1B agonists (1987) (876)
- Catecholamine receptors on locus coeruleus neurons: pharmacological characterization. (1977) (568)
- Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique (1978) (518)
- Noradrenergic neurons of the locus coeruleus: inhibition by epinephrine and activation by the α-antagonist piperoxane (1976) (515)
- Antidromic identification of dopaminergic and other output neurons of the rat substantia nigra (1978) (508)
- Serotonin model of schizophrenia: emerging role of glutamate mechanisms (2000) (485)
- Intracellular studies in the facial nucleus illustrating a simple new method for obtaining viable motoneurons in adult rat brain slices (1989) (477)
- Signaling pathways underlying the rapid antidepressant actions of ketamine (2012) (472)
- Serotonergic facilitation of facial motoneuron excitation (1979) (461)
- Serotonin Induces Excitatory Postsynaptic Potentials in Apical Dendrites of Neocortical Pyramidal Cells (1997) (459)
- Comparison of effects of L-dopa, amphetamine and apomorphine on firing rate of rat dopaminergic neurones. (1973) (451)
- Noradrenergic neurons: morphine inhibition of spontaneous activity. (1974) (432)
- 5-HT2A Receptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex (1997) (422)
- Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice (2006) (400)
- The precise localization of nigral afferents in the rat as determined by a retrograde tracing technique (1976) (383)
- Lysergic Acid Diethylamide: Sensitive Neuronal Units in the Midbrain Raphe (1968) (379)
- Hypocretins (Orexins) Regulate Serotonin Neurons in the Dorsal Raphe Nucleus by Excitatory Direct and Inhibitory Indirect Actions (2002) (367)
- Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex (2012) (357)
- Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: A comparative study with dorsal raphe neurons (1988) (343)
- Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release (1999) (331)
- CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence (1997) (320)
- (-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists. (1986) (320)
- Increased turnover of norepinephrine in the rat cerebral cortex during stress: role of the locus coeruleus. (1973) (317)
- Lysergic acid diethylamide and serotonin: a comparison of effects on serotonergic neurons and neurons receiving a serotonergic input. (1974) (315)
- Serotonin and the neurobiology of depression. Effects of tryptophan depletion in drug-free depressed patients. (1994) (314)
- Action of psychotogenic drugs on single midbrain raphe neurons. (1970) (299)
- Effects of tryptophan depletion in drug-free adults with autistic disorder. (1996) (290)
- Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: Role of corticosterone-mediated apical dendritic atrophy (2008) (286)
- Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex. (2000) (280)
- Nicotine Induces Glutamate Release from Thalamocortical Terminals in Prefrontal Cortex (2003) (266)
- Mechanisms of action of atypical antipsychotic drugs Implications for novel therapeutic strategies for schizophrenia (1991) (261)
- CENTRAL DOPAMINERGIC NEURONS: NEUROPHYSIOLOGICAL IDENTIFICATION AND RESPONSES TO DRUGS* (1973) (249)
- Stimulation and destruction of the locus coeruleus: opposite effects on 3-methoxy-4-hydroxyphenylglycol sulfate levels in the rat cerebral cortex. (1973) (249)
- Dopamine and norepinephrine innervated cells in the rat prefrontal cortex: pharmacological differentiation using microiontophoretic techniques. (1976) (247)
- Pertussis toxin blocks the outward currents evoked by opiate and α2-agonists in locus coeruleus neurons (1986) (237)
- Activation of locus coeruleus neurons by peripheral stimuli: modulation by a collateral inhibitory mechanism. (1978) (236)
- Tryptophan hydroxylase activity and synaptosomal uptake of serotonin in discrete brain regions after midbrain raphe lesions: correlations with serotonin levels and histochemical fluorescence. (1972) (235)
- Hyperpolarization of serotonergic neurons by serotonin and LSD: Studies in brain slices showing increased K+ conductance (1984) (234)
- Lysergic acid diethylamide and serotonin: direct actions on serotonin-containing neurons in rat brain. (1972) (234)
- Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses (2013) (229)
- ACh, substance P and met-enkephalin in the locus coeruleus: pharmacological evidence for independent sites of action. (1979) (228)
- Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway. (1973) (218)
- Tricyclic antidepressants: effects on the firing rate of brain noradrenergic neurons. (1975) (215)
- 5-HT2A receptor or alpha1-adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex. (1999) (212)
- Effect of antipsychotic drugs on the firing of dorsal raphe cells. II. Reversal by picrotoxin. (1976) (210)
- Cytochemistry of Synapses: Selective Staining for Electron Microscopy (1966) (210)
- REDD1 is essential for stress-induced synaptic loss and depressive behavior (2014) (209)
- Common α2- and opiate effector mechanisms in the locus coeruleus: intracellular studies in brain slices (1987) (209)
- Serotonin: Release in the Forebrain by Stimulation of Midbrain Raph� (1967) (208)
- Effect of impulse flow on the release and synthesis of dopamine in the striatum (1973) (205)
- GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine (2013) (204)
- Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions (2015) (204)
- Serotonin-containing neuronal perikarya and terminals: differential effects of P-chlorophenylalanine. (1973) (202)
- Withdrawal-induced activation of locus coeruleus neurons in opiate-dependent rats: attenuation by lesions of the nucleus paragigantocellularis (1989) (200)
- Inhibition of neurons in the amygdala by dorsal raphe stimulation: Mediation through a direct serotonergic pathway (1977) (192)
- Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides (1977) (191)
- Synaptosomes from forebrains of rats with midbrain raphe lesions: selective reduction of serotonin uptake. (1972) (186)
- Opioids suppress spontaneous and NMDA-induced inhibitory postsynaptic currents in the dorsal raphe nucleus of the rat in vitro (1997) (178)
- Modulation of lateral geniculate neurone excitability by noradrenaline microiontophoresis or locus coeruleus stimulation (1980) (174)
- Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2 -activated interneuron (1990) (170)
- Serotonin 5-HT2 receptors activate local GABA inhibitory inputs to serotonergic neurons of the dorsal raphe nucleus (2000) (170)
- Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP‐expressing locus coeruleus (2002) (167)
- Modulation of a transient outward current in serotonergic neurones by α1-adrenoceptors (1985) (164)
- Molecular control of locus coeruleus neurotransmission (1999) (161)
- Evidence for G protein mediation of serotonin- and GABAB- induced hyperpolarization of rat dorsal raphe neurons (1988) (161)
- Pyramidal cells in piriform cortex receive a convergence of inputs from monoamine activated GABAergic interneurons (1993) (156)
- Medial prefrontal D1 dopamine neurons control food intake (2014) (156)
- Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: an electrophysiological study. (1982) (155)
- Rophe neurons: effect of tricyclic antidepressant drugs. (1972) (154)
- Raphe origin of serotonergic nerves terminating in the cerebral ventricles (1975) (153)
- Stimulation of the midbrain raphe: effect on serotonin metabolism. (1968) (149)
- Selective reduction of tryptophan hydroxylase activity in rat forebrain after midbrain raphe lesions. (1971) (148)
- Dopamine “Autoreceptors”: Pharmacological characterization by microiontophoretic single cell recording studies (1977) (141)
- Idazoxan (RX 781094) selectively antagonizes α2-adrenoceptors on rat central neurons (1984) (140)
- Opiate- and alpha 2-adrenoceptor-induced hyperpolarizations of locus ceruleus neurons in brain slices: reversal by cyclic adenosine 3':5'- monophosphate analogues (1985) (138)
- Role of cAMP Response Element-Binding Protein in the Rat Locus Ceruleus: Regulation of Neuronal Activity and Opiate Withdrawal Behaviors (2006) (138)
- Molecular and cellular mechanisms of opiate action: Studies in the rat locus coeruleus (1994) (137)
- LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex. (1996) (137)
- Norepinephrine and serotonin: Opposite effects on the activity of lateral geniculate neurons evoked by optic pathway stimulation (1980) (136)
- Morphine tolerance and dependence in the locus coeruleus: single cell studies in brain slices. (1983) (133)
- alpha 1-Adrenoceptor-mediated responses in the lateral geniculate nucleus are enhanced by chronic antidepressant treatment. (1981) (130)
- Electron microscopy of degeneration within the serotonin pathway of rat brain. (1969) (128)
- Hypocretin and Nicotine Excite the Same Thalamocortical Synapses in Prefrontal Cortex: Correlation with Improved Attention in Rat (2005) (125)
- Histochemical Fluorescence of Raphe Neurons: Selective Enhancement by Tryptophan (1971) (124)
- Brain-Derived Neurotrophic Factor Is Essential for Opiate-Induced Plasticity of Noradrenergic Neurons (2002) (124)
- The cholinergic pharmacology of hippocampal pyramidal cells: A microiontophoretic study (1976) (123)
- Chronic antidepressant treatment enhances alpha-adrenergic and serotonergic responses in the facial nucleus. (1980) (122)
- Locus coeruleus activity in vitro: intrinsic regulation by a calcium- dependent potassium conductance but not alpha 2-adrenoceptors (1984) (121)
- Hypocretin (Orexin) Induces Calcium Transients in Single Spines Postsynaptic to Identified Thalamocortical Boutons in Prefrontal Slice (2003) (120)
- Lewis and Fischer rat strains display differences in biochemical, electrophysiological and behavioral parameters: studies in the nucleus accumbens and locus coeruleus of drug naive and morphine-treated animals (1993) (119)
- Persistence of lysergic acid diethylamide in the plasma of human subjects (1964) (114)
- A Selective AMPA Antagonist, LY293558, Suppresses Morphine Withdrawal-Induced Activation of Locus Coeruleus Neurons and Behavioral Signs of Morphine Withdrawal (1996) (112)
- Influence of drugs on the firing of serotonin-containing neurons in brain. (1972) (111)
- Effect of antipsychotic drugs on the firing of dorsal raphe cells. I. Role of adrenergic system. (1976) (110)
- Mescaline and LSD: direct and indirect effects on serotonin-containing neurons in brain. (1973) (110)
- Activation of lateral geniculate neurons by norepinephrine: Mediation by an α-adrenergic receptor (1980) (107)
- Effect of hallucinogens on spontaneous and sensory-evoked locus coeruleus unit activity in the rat: reversal by selective 5-HT2antagonists (1986) (107)
- The Role of Kv1.2-Containing Potassium Channels in Serotonin-Induced Glutamate Release from Thalamocortical Terminals in Rat Frontal Cortex (2001) (107)
- Chronic antidepressant treatment enhances agonist affinity of brain α1-adrenoceptors (1983) (107)
- Effects of ketanserin on neuronal responses to serotonin in the prefrontal cortex, lateral geniculate and dorsal raphe nucleus (1985) (104)
- Regulation of RGS proteins by chronic morphine in rat locus coeruleus (2003) (102)
- Excitation of interneurons in piriform cortex by 5-hydroxytryptamine: blockade by MDL 100,907, a highly selective 5-HT2A receptor antagonist. (1994) (102)
- The electrophysiology of prefrontal serotonin systems: therapeutic implications for mood and psychosis (1998) (102)
- Serotonin excitation of facial motoneurons: Receptor subtype characterization (1990) (101)
- Single cell activity in the noradrenergic A-5 region: Responses to drugs and peripheral manipulations of blood pressure (1982) (100)
- Regulation of Nucleus Accumbens Activity by the Hypothalamic Neuropeptide Melanin-Concentrating Hormone (2010) (100)
- Neuronally activated metabolism of brain serotonin: effect of lithium. (1970) (95)
- m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Evidence implicating serotonergic systems in the positive symptoms of schizophrenia. (1993) (93)
- Pacemaker potentials of serotonergic dorsal raphe neurons: Contribution of a low‐threshold Ca2+ conductance (1987) (92)
- Activation of lateral geniculate neurons by locus coeruleus or dorsal noradrenergic bundle stimulation: Selective blockade by the alpha1-adrenoceptor antagonist prazosin (1982) (91)
- Inhibition of firing of raphe neurones by tryptophan and 5-hydroxytryptophan: Blockade by inhibiting serotonin synthesis with Ro-4-4602 (1976) (90)
- The physiological role of -adrenoceptors in the CNS: (1983) (89)
- L-Tryptophan as a selective histochemical marker for serotonergic neurons in single-cell recording studies. (1974) (89)
- 5-Hydroxytryptamine-induced excitatory postsynaptic currents in neocortical layer V pyramidal cells: suppression by μ-opiate receptor activation (1998) (89)
- GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine (2017) (85)
- Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra (1985) (84)
- Opiate and alpha 2-adrenoceptor responses of rat amygdaloid neurons: co- localization and interactions during withdrawal (1985) (84)
- Effects of chlorimipramine and lysergic acid diethylamide on efflux of precursor-formed 3-H-serotonin: correlations with serotonergic impulse flow. (1975) (83)
- Neurokinins Activate Local Glutamatergic Inputs to Serotonergic Neurons of the Dorsal Raphe Nucleus (2002) (82)
- Activation of brain serotonin metabolism by heat: Role of midbrain raphe neurons (1971) (82)
- Hypothermic inhibition of 5-hydroxytryptamine and norepinephrine uptake by lung: cellular location of amines after uptake. (1973) (81)
- Serotonin induces EPSCs preferentially in layer V pyramidal neurons of the frontal cortex in the rat. (2000) (80)
- Denervation supersensitivity in the cholinergic septo-hippocampal pathway: A microiontophoretic study (1975) (79)
- Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: Antagonism by atypical antipsychotic drugs (1994) (78)
- Pacemaker activity of locus coeruleus neurons: whole-cell recordings in brain slices show dependence on cAMP and protein kinase A (1991) (77)
- Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity. (1988) (77)
- Alterations in turnover and endogenous levels of norepinephrine in cerebral cortex following electrical stimulation and acute axotomy of cerebral noradrenergic pathways. (1973) (77)
- Response of central monoaminergic neurons to lisuride: comparison with LSD. (1979) (76)
- ELECTROPHYSIOLOGICAL EFFECTS OF AMPHETAMINE ON DOPAMINERGIC NEURONS (1973) (76)
- Patterns of tolerance to lysergic acid diethylamide and mescaline in rats. (1958) (75)
- D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons. (1975) (75)
- Therapeutic Implications of the Hyperglutamatergic Effects of NMDA Antagonists (1999) (75)
- Intracellular studies on the role of calcium in regulating the activity and reactivity of locus coeruleus neurons in vivo (1983) (73)
- Gamma-hydroxybutyrate-induced increase in brain dopamine: localization by fluorescence microscopy. (1970) (73)
- The uptake of 5-hydroxytryptamine-3H from the cerebral ventricles: autoradiographic localization (1966) (70)
- Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. (2006) (67)
- Feedback regulation of central monoaminergic neurons: evidence from single cell recording studies. (1978) (67)
- Distinct Roles of Adenylyl Cyclases 1 and 8 in Opiate Dependence: Behavioral, Electrophysiological, and Molecular Studies (2008) (67)
- LSD and CNS transmission. (1972) (66)
- Prazosin selectively antagonizes neuronal responses mediated by α1-adrenoceptors in brain (1981) (66)
- Atropine, scopolamine, and Ditran: Comparative pharmacology and antagonists in man (2004) (65)
- Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. (1973) (62)
- Suppression of serotogenic neuronal firing by α-adrenoceptor antagonists: Evidence against gaba mediation (1980) (62)
- Correlation of performance test scores with “tissue concentration” of lysergic acid diethylamide in human subiects (1968) (61)
- Mescaline and LSD facilitate the activation of locus coeruleus neurons by peripheral stimuli (1980) (60)
- Peripheral serotonin antagonists: Failure to antagonize serotonin in brain areas receiving a prominent serotonergic input (2005) (57)
- Schizophrenia, hypocretin (orexin), and the thalamocortical activating system. (2006) (56)
- Hallucinogen-Induced UP States in the Brain Slice of Rat Prefrontal Cortex: Role of Glutamate Spillover and NR2B-NMDA Receptors (2006) (55)
- MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin. (1989) (55)
- LSD and 2-Bromo-Lsd: Comparison of effects on serotonergic neurones and on neurones in two serotonergic projection areas, the ventral lateral geniculate and amygdala (1976) (52)
- d-Amphetamine-induced depression of central dopamine neurons: Evidence for mediation by both autoreceptors and a striato-nigral feedback pathway (1978) (51)
- Functional supersensitivity of CNS α1-adrenoceptors following chronic antidepressant treatment (1983) (51)
- Cholecystokinin-containing and nociceptive neurons in rat edinger-westphal nucleus (1986) (51)
- Neurotensin and the serotonergic system (1997) (50)
- Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses (2015) (49)
- Serotonin–Glutamate Interactions: A New Target for Antipsychotic Drugs (1999) (48)
- Stimulation of midbrain raphé neurons: behavioral effects of serotonin release. (1968) (48)
- Delayed iontophoretic ejection of substance P from glass micropipettes: Correlation with time-course of neuronal excitation in vivo (1979) (47)
- Intrinsic regulation of locus coeruleus neurons: electrophysiological evidence indicating a predominant role for autoinhibition (1984) (47)
- Phenethylamine hallucinogens in the locus coeruleus: potency of action correlates with rank order of 5-HT2 binding affinity. (1986) (47)
- Amine Receptors in CNS. III. 5-Hydroxytryptamine in Brain (1975) (45)
- α 1-adrenoceptordenervation supersensitivity in brain: Physiological and receptor binding studies (1983) (43)
- Interaction of histamine H2-receptor antagonists with GABA and benzodiazepine binding sites in the CNS. (1983) (42)
- Selective accumulation of 3 H-serotonin by nerve terminals of raphe neurones: an autoradiographic study. (1973) (42)
- Synthesis of catecholamines in the locus coeruleus from 3 H-tyrosine in vivo. (1972) (40)
- Modeling “psychosis” in vitro by inducing disordered neuronal network activity in cortical brain slices (2009) (39)
- Effects of apomorphine and haloperidol on the acoustic startle response in rats (1976) (39)
- Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β (2014) (38)
- Modulation of a transient outward current in serotonergic neurones by alpha 1-adrenoceptors. (1985) (37)
- Indoleamine and the phenethylamine hallucinogens: mechanisms of psychotomimetic action. (1998) (37)
- Effects of d- and l-amphetamine on habituation and sensitization of the acoustic startle response in rats (1975) (37)
- Effects of histamine, H1- and H2-receptor antagonists on the activity of serotonergic neurons in the dorsal raphe nucleus. (1983) (37)
- Alpha 1B-adrenoceptor-mediated excitation of piriform cortical interneurons. (1996) (36)
- Adrenergic hyperactivity of the aganglionic colon. (1973) (35)
- Serotonin-induced inward current in rat facial motoneurons: evidence for mediation byG proteins but not protein kinase C (1990) (33)
- Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats (1977) (33)
- Pharmacological characterization of dopamine "autoreceptors" by microiontophoretic single-cell recording studies. (1977) (33)
- Activation of lateral geniculate neurons by norepinephrine: mediation by an alpha-adrenergic receptor. (1980) (33)
- Adenosine preferentially suppresses serotonin2A receptor-enhanced excitatory postsynaptic currents in layer V neurons of the rat medial prefrontal cortex (2001) (33)
- Idazoxan (RX 781094) selectively antagonizes alpha 2-adrenoceptors on rat central neurons. (1984) (32)
- QX-314 blocks the potassium but not the sodium-dependent component of the opiate response in locus coeruleus neurons (1994) (32)
- Caveat Emptor: Researcher Beware (1999) (31)
- Failure to block responses of locus coeruleus neurons to somatosensory stimuli by destruction of two major afferent nuclei (1989) (31)
- Excitation of locus coeruleus neurons by vasoactive intestinal peptide: evidence for a G-protein-mediated inward current (1989) (30)
- Prefrontal cortical network activity: Opposite effects of psychedelic hallucinogens and D1/D5 dopamine receptor activation (2007) (30)
- Tryptophan-deficient diet and amino acid drink deplete plasma tryptophan and induce a relapse of depression in susceptible patients (1992) (30)
- Central dopaminergic neurons: Neurophysiological identification and responses to drugs (1974) (28)
- A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neurons. (1974) (27)
- Magnesium Pemoline: Failure To Affect in vivo Synthesis of Brain RNA (1967) (27)
- Serotonin receptors in the brain. (1977) (26)
- Central noradrenergic neurons: a locus for the functional interplay between alpha-2 adrenoceptors and opiate receptors. (1982) (26)
- Excitatory amino acids and morphine withdrawal: differential effects of central and peripheral kynurenic acid administration (2005) (26)
- A method of direct chemical brain stimulation in behavioral studies using microiontophoresis (1975) (26)
- Frontiers in catecholamine researchCentral dopaminergic neurons: Neurophysiological identification and responses to drugs (1973) (26)
- Serotonin and the Action of LSD in the Brain (1994) (25)
- Histamine-induced depression of serotoninergic dorsal raphe neurons: antagonism by cimetidine, a reevaluation. (1984) (25)
- DIRECT AND INDIRECT ACTIONS OF LSD, SEROTONIN AND RELATED COMPOUNDS ON SEROTONIN-CONTAINING NEURONS (1973) (24)
- Evidence for drug actions on both pre- and postsynaptic catecholamine receptors in the CNS. (1975) (23)
- Long-term glutamate desensitization in locus coeruleus neurons and its role in opiate withdrawal (1995) (23)
- 3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan. (1990) (23)
- Use of Single Unit Recording in Correlating Transmitter Turnover with Impulse Flow in Monoamine Neurons (1973) (22)
- Activation of locus coeruleus (LC) neurones by cholera toxin: Mediation by cAMP-dependent protein kinase (1991) (21)
- Use of the whole-cell patch-clamp method in studies on the role of cAMP in regulating the spontaneous firing of locus coeruleus neurons (1995) (20)
- Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release. (1991) (20)
- In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements (1991) (19)
- Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics. (1975) (19)
- Electrophysiology of Central Serotonin Receptor Subtypes (1988) (19)
- Electrophysiology of 5-HT Receptors (2000) (18)
- Adrenergic Denervation of the Hypertrophied Gut Remnant (1972) (17)
- Protein kinase C inhibitors enhance the 5‐HT2A receptor‐mediated excitatory effects of serotonin on interneurons in rat piriform cortex (1995) (17)
- Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities (2020) (15)
- An evaluation of the use of intraventricularly administered [3H]5-hydroxytryptamine as a marker for endogenous brain 5-hydroxytryptamine (1975) (14)
- Intracellular GTPγS restores the ability of morphine to hyperpolarize rat locus coeruleus neurons after blockade by pertussis toxin (1987) (13)
- Baclofen-assisted detoxification from opiates. A pilot study. (1992) (13)
- 3,4-methylenedioxymethamphetamine (MDMA)-induced release of endogenous serotonin from the rat dorsal raphe nucleus in vitro: Effects of fluoxetine and tryptophan (1990) (12)
- Functional supersensitivity of CNS alpha 1-adrenoceptors following chronic antidepressant treatment. (1983) (12)
- Prospects for research on schizophrenia. V. Pharmacological observations, Drug-induced psychoses. (1972) (11)
- "Microsome" Fraction of Brain: Structural Changes Induced by Ascorbic Acid (1963) (11)
- Regulation of serotonergic neuronal activity: autoreceptors and pacemaker potentials. (1982) (11)
- D-Amphetamine-induced inhibition of central dopaminergic neurons: direct effect or mediated by a striatonigral feedback pathway? (1977) (10)
- Chronic antidepressant treatment enhances agonist affinity of brain alpha 1-adrenoceptors. (1983) (10)
- The Reversal of Anticholinergic Intoxication in Man with the Cholinesterase Inhibitor VX (1973) (10)
- Principles of psychopharmacology : a textbook for physicians, medical students, and behavioral scientists (1970) (9)
- Mode of action of LSD on serotonergic neurons. (1974) (9)
- Response of single raphé neurons to (+)‐LSD: correlation with (+)‐LSD binding in brain (1976) (8)
- Treatment of benign essential blepharospasm with cyproheptadine. (1990) (8)
- Electrophysiological studies on the actions of hallucinogenic drugs at 5-HT2 receptors in rat brain. (1994) (7)
- Alpha 1-adrenoceptor denervation supersensitivity in brain: physiological and receptor binding studies. (1983) (7)
- Glutamate NMDA receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure (2011) (7)
- CENTRAL NORADRENERGIC NEURONS: INTERACTION OF AUTOREGULATORY MECHANISMS WITH EXTRINSIC INFLUENCES (1979) (7)
- The effect of chlorpromazine on respiration of brain mitochondria as a function of metabolic state. (1963) (7)
- Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity. (1994) (7)
- Dopaminergic infllence in the basal ganglia: evidence for striatonigral feedback regulation. (1976) (7)
- Pertussis toxin or 8-bromo-cAMP block inhibition of the acoustic startle response by the α2-adrenergic agonist ST-91 (1987) (6)
- Scopolamine rapidly increases mTORC1 signaling, synaptogenesis, and antidepressant behavioral responses (2013) (6)
- Behavioral effects of acute tryptophan depletion in depressed patients (1989) (5)
- Electrophysiological studies of dopamine- innervated cells in the frontal cortex. (1977) (5)
- THE HUMAN ASSESSMENT OF EA 1729 AND EA 3528 BY THE INHALATION ROUTE (1964) (5)
- BDNF Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex (2012) (5)
- LY 354740 : A Systemically Active mGlu 2 / mGlu 3 Receptor Agonist (1999) (5)
- Using Basic Electrophysiology to Understand the Neurobiology of Mental Illness (2011) (4)
- Electrophysiology of 5-HT2A Receptors and Relevance for Hallucinogen and Atypical Antipsychotic Drug Actions (2006) (4)
- Serotonin-containing neurons in the central nervous system. (1972) (4)
- Serotonin (5-Hydroxytryptamine; 5-HT): CNS Pathways and Neurophysiology (2009) (4)
- Electrophysiology of Brain Serotonin Receptors: Subtype Specificity for Effector Mechanisms (1990) (3)
- Serotonin neurons: a synaptic mechanism for the reuptake of serotonin. (1974) (3)
- Proceedings: Differentiation between neuroleptic antipsychotic properties and side effects by subgroups of dopaminergic neurons. (1974) (1)
- Antipsychotic drugs and amphetamine: direct evidence for an action on dopaminergic neurons (1974) (1)
- Patricia Goldman-Rakic, 1937–2003 (2003) (1)
- Effects Of Hypocretin/Orexin on the Thalamocortical Activating System (2005) (0)
- Psychotogenic drug action on chemically defined neurons. (1975) (0)
- Editorial Board (1994) (0)
- Rapid Antidepressant Effects of NMDA Receptor Blockade Require Synaptic Protein Synthesis and Spine Formation (2010) (0)
- Rapid Antidepressant Effects of NMDA Antagonists mTOR-Dependent Synapse Formation Underlies (2010) (0)
- Torgny Svensson, M.D., Ph.D. (1945–2020) (2020) (0)
- Editorial Board (1984) (0)
- Psychotogenic drug action on chemically defined neurons. (1979) (0)
- 18. Hallucinogen-induced EPSPS in neocortical pyramidal cells (1998) (0)
- Acknowledgement to Reviewers (1994) (0)
- Intracellular Application of Macromolecules Through Patch Pipettes in Brain Slices (2020) (0)
- S.11.2 - PREFRONTAL D1 NEURONS AND REGULATION OF FOOD INTAKE (2013) (0)
- Editorial Board (2003) (0)
- 2013 Daniel H. Efron Research Award (2012) (0)
- The Neuroscience Research Program at the Connecticut Mental Health Center (2007) (0)
- CENTRAL DOPAMINERGIC NEURONS: NEUROPHYSIOLOGICAL IDENTIFICATION AND RESPONSES TO DRUGS**This research was supported by NIMH Grant MH-17871, USPHS Research Scientist Development Award MH-14459 (to G. K. A.), and the State of Connecticut. (1973) (0)
- Tolerance, antagonism and the relation between D-lysergic acid diethylamide and mescaline (1958) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With George K. Aghajanian?
George K. Aghajanian is affiliated with the following schools:
