George Kassiotis
#162,471
Most Influential Person Now
Researcher
George Kassiotis's AcademicInfluence.com Rankings
George Kassiotiscomputer-science Degrees
Computer Science
#9454
World Rank
#9928
Historical Rank
Machine Learning
#4138
World Rank
#4187
Historical Rank
Artificial Intelligence
#4481
World Rank
#4542
Historical Rank
Database
#6419
World Rank
#6652
Historical Rank
Download Badge
Computer Science
George Kassiotis's Degrees
- Bachelors Computer Science Imperial College London
Similar Degrees You Can Earn
Why Is George Kassiotis Influential?
(Suggest an Edit or Addition)George Kassiotis's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Regulatory T Cells (2011) (2177)
- Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia (2006) (1516)
- Preexisting and de novo humoral immunity to SARS-CoV-2 in humans (2020) (720)
- Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination (2021) (414)
- Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level (2001) (372)
- Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. (1998) (343)
- T Cell Regulation as a Side Effect of Homeostasis and Competition (2003) (306)
- On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease (1999) (279)
- The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease (1999) (207)
- Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers (2020) (202)
- Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers (2020) (202)
- Involvement of Avidity for Major Histocompatibility Complex in Homeostasis of Naive and Memory T Cells (2003) (201)
- Impairment of immunological memory in the absence of MHC despite survival of memory T cells (2002) (200)
- Resurrection of endogenous retroviruses in antibody-deficient mice (2012) (185)
- Endogenous Retroviruses and the Development of Cancer (2014) (168)
- Immune responses to endogenous retroelements: taking the bad with the good (2016) (159)
- Z-nucleic acid sensing triggers ZBP1-dependent necroptosis and inflammation (2020) (158)
- Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis1 (2005) (158)
- TNF-α transgenic and knockout models of CNS inflammation and degeneration (1997) (151)
- Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis. (1995) (109)
- CD4+ memory T cells: functional differentiation and homeostasis (2006) (105)
- Learning abilities, NGF and BDNF brain levels in two lines of TNF-α transgenic mice, one characterized by neurological disorders, the other phenotypically normal (1999) (103)
- Estimating the effectiveness of routine asymptomatic PCR testing at different frequencies for the detection of SARS-CoV-2 infections (2020) (102)
- TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein‐induced experimental autoimmune encephalomyelitis (1999) (97)
- Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: The CAPTURE study (2021) (97)
- AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC (2021) (95)
- Homeostasis and T cell regulation. (2004) (87)
- Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells (2020) (80)
- Suppression of Innate Immune Pathology by Regulatory T Cells during Influenza A Virus Infection of Immunodeficient Mice (2010) (80)
- Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retroelement co-option (2020) (79)
- Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis (2013) (69)
- SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity (2021) (68)
- TNF-alpha transgenic and knockout models of CNS inflammation and degeneration. (1997) (68)
- Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma (2021) (68)
- Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients (2021) (65)
- Retrovirus-Specificity of Regulatory T Cells Is Neither Present nor Required in Preventing Retrovirus-Induced Bone Marrow Immune Pathology (2008) (65)
- The concept of space and competition in immune regulation (2004) (63)
- T cell regulation: a special job or everyone's responsibility? (2001) (59)
- Anatomical Heterogeneity of Memory CD4+ T Cells Due to Reversible Adaptation to the Microenvironment1 (2004) (57)
- Three-dose vaccination elicits neutralising antibodies against omicron (2022) (57)
- LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly (2019) (55)
- A Major Role for Memory CD4 T Cells in the Control of Lymphopenia-Induced Proliferation of Naive CD4 T Cells1 (2005) (55)
- CD4 T-cell memory. (2004) (54)
- Making a virtue of necessity: the pleiotropic role of human endogenous retroviruses in cancer (2017) (53)
- Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2 (2021) (52)
- Cytokine release syndrome in a patient with colorectal cancer after vaccination with BNT162b2 (2021) (52)
- Tetherin Promotes the Innate and Adaptive Cell–Mediated Immune Response against Retrovirus Infection In Vivo (2014) (51)
- Dissection of the pathologies induced by transmembrane and wild‐type tumor necrosis factor in transgenic mice (1996) (51)
- Negative Selection by an Endogenous Retrovirus Promotes a Higher-Avidity CD4+ T Cell Response to Retroviral Infection (2012) (50)
- Functional Specialization of Memory Th Cells Revealed by Expression of Integrin CD49b1 (2006) (48)
- Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer (2022) (46)
- SARS-CoV-2 virus and antibodies in front-line Health Care Workers in an acute hospital in London: preliminary results from a longitudinal study (2020) (45)
- B Lymphocyte Activation by Coinfection Prevents Immune Control of Friend Virus Infection1 (2008) (44)
- Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus (2016) (43)
- Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes (2014) (42)
- Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota (2021) (41)
- TNF and receptors in organ-specific autoimmune disease: multi-layered functioning mirrored in animal models. (2001) (41)
- Race between Retroviral Spread and CD4+ T-Cell Response Determines the Outcome of Acute Friend Virus Infection (2009) (40)
- A tumor necrosis factor‐induced model of human primary demyelinating diseases develops in immunodeficient mice (1999) (39)
- B Cells and TCR Avidity Determine Distinct Functions of CD4+ T Cells in Retroviral Infection (2011) (39)
- The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies. (2002) (39)
- Tumor necrosis factor‐α regulation of insulin‐like growth factor‐I, type 1 IGF receptor, and IGF binding protein expression in cerebellum of transgenic mice (2003) (38)
- Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains (2021) (36)
- Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed by RNA-Sequencing of B Lymphocytes (2017) (32)
- Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer (2021) (32)
- IL-2–Independent and TNF-α–Dependent Expansion of Vβ5+ Natural Regulatory T Cells during Retrovirus Infection (2013) (32)
- Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth (2021) (31)
- Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses (2021) (30)
- Noncognate Interaction with MHC Class II Molecules Is Essential for Maintenance of T Cell Metabolism to Establish Optimal Memory CD4 T Cell Function1 (2007) (30)
- Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells. (2010) (29)
- Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model (2011) (28)
- Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection (2016) (26)
- Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. (2021) (26)
- the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (TNF) at the p55 TNF Receptor Level: Implications for Pathogenesis and Therapy of Autoimmune Demyelination (2001) (26)
- Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness (2001) (25)
- ADAR1 averts fatal type I interferon induction by ZBP1 (2022) (25)
- Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients (2022) (25)
- Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist (2019) (25)
- SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies (2022) (24)
- A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus (2019) (22)
- Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response (2016) (22)
- Transgenic models of TNF induced demyelination. (1999) (21)
- Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer (2021) (20)
- Establishing the follicular helper identity. (2009) (20)
- Negative Impact of IFN-γ on Early Host Immune Responses to Retroviral Infection (2012) (19)
- Functional antibody and T-cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study (2021) (19)
- Generalized immune activation as a direct result of activated CD4+ T cell killing (2009) (18)
- Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression (2019) (16)
- Counterpoise between the microbiome, host immune activation and pathology. (2013) (16)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay. (2021) (16)
- Immunity Benefits from a Little Suppression (2008) (16)
- Recovery of an Antiviral Antibody Response following Attrition Caused by Unrelated Infection (2014) (16)
- Scalable and robust SARS-CoV-2 testing in an academic center (2020) (15)
- Restoration of Endogenous Retrovirus Infectivity Impacts Mouse Cancer Models (2018) (15)
- Restriction of memory B cell differentiation at the germinal center B cell positive selection stage (2020) (15)
- Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study. (2021) (15)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay (2020) (14)
- Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity (2019) (13)
- SARS-CoV-2 recruits a haem metabolite to evade antibody immunity (2021) (13)
- Clonotypic Composition of the CD4+ T Cell Response to a Vectored Retroviral Antigen Is Determined by Its Speed (2014) (12)
- Heterologous humoral immunity to human and zoonotic coronaviruses: Aiming for the achilles heel (2021) (11)
- Scalable and Resilient SARS-CoV2 testing in an Academic Centre (2020) (11)
- MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells. (2019) (11)
- 1557O Adaptive immunity to SARS-CoV-2 infection and vaccination in cancer patients: The CAPTURE study (2021) (10)
- Effective T helper cell responses against retroviruses: are all clonotypes equal? (2014) (10)
- SARS-CoV-2-Host Chimeric RNA-Sequencing Reads Do Not Necessarily Arise From Virus Integration Into the Host DNA (2021) (10)
- An immunogenic model of KRAS-mutant lung cancer enables evaluation of targeted therapy and immunotherapy combinations. (2022) (10)
- Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response (2015) (9)
- Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice (2012) (8)
- Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer (2022) (7)
- Antibody-induced internalisation of retroviral envelope glycoproteins is a signal initiation event (2020) (7)
- The evolution of lung cancer and impact of subclonal selection in TRACERx (2023) (7)
- Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retrovirus co-option (2020) (7)
- Genomic–transcriptomic evolution in lung cancer and metastasis (2023) (6)
- Correlates of Follicular Helper Bias in the CD4 T Cell Response to a Retroviral Antigen (2018) (6)
- Regulatory T cells constrain the TCR repertoire of antigen‐stimulated conventional CD4 T cells (2018) (6)
- The evolution of non-small cell lung cancer metastases in TRACERx (2023) (6)
- Mutation of the Putative Immunosuppressive Domain of the Retroviral Envelope Glycoprotein Compromises Infectivity (2017) (6)
- Recognition of Z-RNA by ADAR1 limits interferon responses (2020) (5)
- Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases (2021) (5)
- Modulation of IL-6/STAT3 signaling axis in CD4+FOXP3- T cells represents a potential antitumor mechanism of azacitidine. (2021) (5)
- Influence of IL-6 levels on patient survival in COVID-19 (2021) (4)
- Regulatory T cells constrain the TCR repertoire of antigen-stimulated conventional CD 4 T cells (2017) (4)
- Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA (2023) (4)
- Antibodies against endogenous retroviruses promote lung cancer immunotherapy (2023) (3)
- Default polyfunctional T helper 1 response to ample signal 1 alone (2020) (3)
- Lung adenocarcinoma promotion by air pollutants (2023) (3)
- Publisher Correction: Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation (2020) (3)
- SARS-CoV-2-host chimeric RNA-sequencing reads do not necessarily signify virus integration into the host DNA (2021) (2)
- Determinants of anti-PD1 response and resistance in clear cell renal cell carcinoma (2021) (2)
- Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression (2021) (2)
- Sex differences in immunological responses to COVID-19: a cross-sectional analysis of a single-centre cohort (2021) (2)
- E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion (2021) (2)
- Non-hospitalised, vaccinated adults with COVID-19 caused by Omicron BA.1 and BA.2 present with changing symptom profiles compared to those with Delta despite similar viral kinetics (2022) (2)
- Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice (2012) (1)
- Lymphocyte Activation by Coinfection Prevents Immune Control of Friend Virus Infection 1 (2008) (1)
- Defining Potential Therapeutic Targets in Coronavirus Disease 2019: A Cross-Sectional Analysis of a Single-Center Cohort (2021) (1)
- Cytokine release syndrome in a patient with colorectal cancer following vaccination with BNT162b2 (tozinameran) (2021) (1)
- An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations (2022) (1)
- Author response: Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist (2019) (1)
- Evolutionary characterisation of lung adenocarcinoma morphology in TRACERx (2023) (1)
- IL27 gene expression distinguishes multisystem inflammatory syndrome in children from febrile illness in a South African cohort (2022) (1)
- Broad human and animal coronavirus neutralisation by SARS-CoV-2 S2-targeted vaccination (2021) (1)
- Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center (2020) (1)
- The Immunological Conundrum of Endogenous Retroelements. (2022) (1)
- Correction: A Unique Dermal Dendritic Cell Subset That Skews the Immune Response toward Th2 (2014) (0)
- High avidity virus-specific CD4+T cells are lost during retroviral infection upon cognate interaction with B cells (2009) (0)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 2 approved with reservations] (2021) (0)
- Defining Potential Therapeutic Targets in COVID-19: A Cross-Sectional Analysis of a Single Centre Cohort (2021) (0)
- Session 9: Immune regulation (2004) (0)
- Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes (2014) (0)
- 509 Immune checkpoint blockade boosts anti-tumour B cell responses in lung adenocarcinoma (2022) (0)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [ version 2 ; peer review : 2 approved ] (2021) (0)
- PS1334 THERAPEUTIC RESPONSE OF MYELODYSPLASTIC SYNDROMES TO EPIGENETIC DRUGS INDEPENDENTLY OF ENDOGENOUS RETROELEMENT MODULATION (2019) (0)
- Memory CD4 T Cell Function Cell Metabolism to Establish Optimal Molecules Is Essential for Maintenance of T Noncognate Interaction with MHC Class II (2007) (0)
- Dichotomy between T Cell and B Cell Tolerance to Neonatal Retroviral Infection Permits T Cell Therapy (2016) (0)
- Modulation of the IL-6/STAT3 Signaling Axis in CD4+ T Cells As a Potential Immune Mechanism of Action of Azacytidine in High-Risk Myelodysplastic Syndromes (2019) (0)
- The TNF/TNF receptor system in CNS Disease: Studies in transgenic and mutant mice (1998) (0)
- P16-26. High avidity virus-specific CD4+ T cells are lost during retroviral infection due to interaction with B cells (2009) (0)
- Role for TNF in CNS Inflammation, Demyelination and Neurodegeneration Studied in Transgenic Mice (1998) (0)
- Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer (2023) (0)
- Regulatory role of TNF in experimental ocular inflammation (1998) (0)
- Default polyfunctional T helper 1 response to ample signal 1 alone (2020) (0)
- MicroenvironmentT Cells Due to Reversible Adaptation to the + Anatomical Heterogeneity of Memory CD4 (2004) (0)
- Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells (2023) (0)
- Local TNF ligand/receptor signaling induces MS-type plaques in the CNS of transgenic mice (1998) (0)
- P03-05. CD4 targeted vaccination in retroviral infection (2009) (0)
- Retrovirus Infection In Vivo Mediated Immune Response against - Cell Tetherin Promotes the Innate and Adaptive (2014) (0)
- Comprar Regulatory T Cells. Methods And Protocols (Methods In Molecular Biology, Vol. 707) | A. Liston | 9781617379789 | Humana Press (2011) (0)
- Suppression of Innate Immune Pathology by Regulatory T Cells during Influenza A Virus Infection of Immunodeficient Mice (cid:1) † (2010) (0)
- Abstract 1390: Immunotherapy boosts B cell responses in lung adenocarcinoma (2022) (0)
- Regulatory TCells Restrain Interleukin-2- andBlimp- 1-Dependent Acquisition of Cytotoxic Function by CD4 T Cells (2020) (0)
- Regulatory T-Cells: Methods and Protocols (2023) (0)
- The Therapeutic Response of Myelodsyplastic Syndromes to Azacytidine Is Independent of Endogenous Retroelement Modulation (2018) (0)
- Body composition and lung cancer-associated cachexia in TRACERx (2023) (0)
- Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases (2021) (0)
- Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression (2019) (0)
- TNF-triggered CNS inflammation, demyelination and T cell autoreactivity in transgenic mice: A role for mature lymphocytes in disease modulation but not disease initiation (1997) (0)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 1; peer review: 1 approved with reservations] (2021) (0)
- 343 Identification of tumor-reactive T cells targeting melanoma Dark Antigens™ validates this novel class of targets for development of immunotherapies (2022) (0)
- Race between Retroviral Spread and CD4 (cid:1) T-Cell Response Determines the Outcome of Acute Friend Virus Infection (cid:1) (2009) (0)
- Revealed by Expression of Integrin CD49b Functional Specialization of Memory Th Cells (2006) (0)
- Antigenicity of peptides comprising the immunosuppressive domain of the retroviral envelope glycoprotein (2016) (0)
- Journal Pre-proof Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases (2021) (0)
- CD4+ T cell memory is impaired by species-specific cytotoxic differentiation, but not by TCF-1 loss (2023) (0)
- Abstract not submitted for online publication (2009) (0)
- Encephalomyelitis Experimental Autoimmune TNF-R 1 Is a Key Event in the Induction of Apoptosis of Oligodendrocytes via Fas and (2005) (0)
- Retrovirus Infection Natural Regulatory T + 5 β Expansion of V Dependent − α Independent and TNF-− IL-2 and (2013) (0)
- A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819 (2022) (0)
- Determined by Its Speed Response to a Vectored Retroviral Antigen Is T Cell + Clonotypic Composition of the CD4 (2014) (0)
- Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation (2020) (0)
- SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay [version 2; peer review: 2 approved with reservations] (2021) (0)
- Proliferation of Naive CD 4 T Cells Control of Lymphopenia-Induced A Major Role for Memory CD 4 T Cells in the Stockinger (2005) (0)
- Publisher Correction: Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation (2020) (0)
- Clinical and Translational Article Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases (2021) (0)
- Innate virus-sensing pathways in B cell systemic autoimmunity (2023) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With George Kassiotis?
George Kassiotis is affiliated with the following schools:
