George Church
#14,589
Most Influential Person Now
Geneticist, molecular engineer, chemist
George Church 's AcademicInfluence.com Rankings
George Church biology Degrees
Biology
#833
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#1443
Historical Rank
#448
USA Rank
Biotechnology
#6
World Rank
#6
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#3
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Bioinformatics
#12
World Rank
#12
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#5
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Computational Biology
#12
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#12
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#8
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Chemistry Biology
George Church 's Degrees
- Bachelors Zoology Duke University
Why Is George Church Influential?
(Suggest an Edit or Addition)George M. Church is the Robert Winthrop Professor of Genetics at Harvard Medical School and a Professor of Health Sciences and Technology at Harvard and the Massachusetts Institute of Technology. He is also a member of the Bulletin of the Atomic Scientists’ Board of Sponsors. He earned a bachelor’s degree in zoology and chemistry from Duke University. He went on to a graduate biochemistry program at Duke, but became so immersed in his lab work that he abandoned his other coursework and ended up getting withdrawn from the program. Undeterred, he went on to earn a Ph.D. in chemistry and molecular biology from Harvard University.
Best known for his work in genome engineering and synthetic biology, Church is credited with pioneering the fields of synthetic biology and personal genomics. He has provided significant leadership in his field, with positions at the Center on Bioenergy Technology and Center of Excellence in Genomic Science at Harvard, as well as at Veritas Genetics and Veritas International, which he co-founded.
Church has recently been criticized for his use of Jeffrey Epstein as a source of funding for his research. The Jeffrey Epstein VI Foundation has been providing funding for research under Church since 2005 and continues to this day.
Featured in Top Influential Biologists Today and Top Influential Engineers Today
According to Wikipedia, George McDonald Church is an American geneticist, molecular engineer, chemist, serial entrepreneur, and pioneer in personal genomics and synthetic biology. He is the Robert Winthrop Professor of Genetics at Harvard Medical School, Professor of Health Sciences and Technology at Harvard University and Massachusetts Institute of Technology, and a founding member of the Wyss Institute for Biologically Inspired Engineering at Harvard. Through his Harvard lab Church has co-founded around 50 biotech companies pushing the boundaries of innovation in the world of life sciences and making his lab as a hotbed of biotech startup activity in Boston. In 2018, the Church lab at Harvard made a record by spinning off 16 biotech companies in one year. The Church lab works on research projects that are distributed in diverse areas of modern biology like developmental biology, neurobiology, info processing, medical genetics, genomics, gene therapy, diagnostics, chemistry & bioengineering, space biology & space genetics, and ecosystem. Research and technology developments at the Church lab have impacted or made direct contributions to nearly all "next-generation sequencing " methods and companies. In 2017, Time magazine listed him in Time 100, the list of 100 most influential people in the world. In 2022, he was featured among the most influential people in biopharma by Fierce Pharma, and was listed among the top 8 famous geneticists of all time in human history. , Church serves as a member of the Bulletin of the Atomic Scientists' Board of Sponsors, established by Albert Einstein.
George Church 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- RNA-Guided Human Genome Engineering via Cas9 (2013) (7947)
- Genomic sequencing. (1984) (5181)
- Systematic determination of genetic network architecture (1999) (2701)
- Biclustering of Expression Data (2000) (2345)
- The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
- A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads (2012) (1705)
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering (2013) (1642)
- Assessing computational tools for the discovery of transcription factor binding sites (2005) (1393)
- Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems (2013) (1379)
- Programming cells by multiplex genome engineering and accelerated evolution (2009) (1362)
- Analysis of optimality in natural and perturbed metabolic networks (2002) (1300)
- Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9 (2013) (1209)
- Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays (2010) (1188)
- Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome (2005) (1144)
- Cas9 as a versatile tool for engineering biology (2013) (1135)
- Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae. (2000) (1131)
- Highly-efficient Cas9-mediated transcriptional programming (2014) (1084)
- Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation (1998) (1062)
- Rapid prototyping of 3D DNA-origami shapes with caDNAno (2009) (941)
- Next-Generation Digital Information Storage in DNA (2012) (919)
- Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization (1997) (910)
- CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing (2014) (884)
- Heritable genome editing in C. elegans via a CRISPR-Cas9 system (2013) (872)
- In vivo gene editing in dystrophic mouse muscle and muscle stem cells (2016) (864)
- A Deep Learning Approach to Antibiotic Discovery (2020) (832)
- Cover Picture: Recoding the Genetic Code with Selenocysteine (Angew. Chem. Int. Ed. 1/2014) (2014) (824)
- Modeling Gene Expression with Differential Equations (1998) (814)
- Functional Characterization of the Antibiotic Resistance Reservoir in the Human Microflora (2009) (785)
- Highly Multiplexed Subcellular RNA Sequencing in Situ (2014) (784)
- Optical Control of Mammalian Endogenous Transcription and Epigenetic States (2013) (771)
- Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. (2011) (750)
- Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes. (1994) (727)
- Clinical assessment incorporating a personal genome (2010) (692)
- Identifying regulatory networks by combinatorial analysis of promoter elements (2001) (688)
- B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. (1985) (666)
- Genomically Recoded Organisms Expand Biological Functions (2013) (649)
- DNA sequencing at 40: past, present and future (2017) (645)
- Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae (2001) (641)
- Concerning RNA-guided gene drives for the alteration of wild populations (2014) (640)
- Corrigendum: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells (2009) (637)
- Meta-analysis of age-related gene expression profiles identifies common signatures of aging (2009) (616)
- Identification of many microRNAs that copurify with polyribosomes in mammalian neurons (2003) (599)
- Modular epistasis in yeast metabolism (2005) (593)
- Large-scale de novo DNA synthesis: technologies and applications (2014) (591)
- Advanced sequencing technologies: methods and goals (2004) (590)
- Orthogonal Cas9 Proteins for RNA-Guided Gene Regulation and Editing (2013) (569)
- Synthetic Gene Networks That Count (2009) (566)
- A prudent path forward for genomic engineering and germline gene modification (2015) (565)
- A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression (2000) (555)
- Unified rational protein engineering with sequence-based deep representation learning (2019) (538)
- Extensive sequencing of seven human genomes to characterize benchmark reference materials (2015) (529)
- The Brain Activity Map Project and the Challenge of Functional Connectomics (2012) (526)
- Aligning gene expression time series with time warping algorithms (2001) (526)
- Tuberculosis Drug Resistance Mutation Database (2009) (524)
- Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing (2009) (521)
- Bacteria Subsisting on Antibiotics (2007) (514)
- Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 (2017) (513)
- Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement (2011) (499)
- Genome-wide inactivation of porcine endogenous retroviruses (PERVs) (2015) (493)
- Patterns and Implications of Gene Gain and Loss in the Evolution of Prochlorococcus (2007) (491)
- Causes and Effects of N-Terminal Codon Bias in Bacterial Genes (2013) (483)
- Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy (2015) (469)
- Modeling the mitochondrial cardiomyopathy of Barth syndrome with iPSC and heart-on-chip technologies (2014) (466)
- Multiplex amplification of large sets of human exons (2007) (463)
- A multifunctional AAV–CRISPR–Cas9 and its host response (2016) (455)
- Photosynthesis genes in marine viruses yield proteins during host infection (2005) (454)
- Generation of functional human hepatic endoderm from human induced pluripotent stem cells (2009) (446)
- From genetic privacy to open consent (2008) (440)
- Targeted and genome-scale methylomics reveals gene body signatures in human cell lines (2009) (434)
- Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset (2005) (424)
- Towards synthesis of a minimal cell (2006) (411)
- Sequencing genomes from single cells by polymerase cloning (2006) (409)
- Syntrophic exchange in synthetic microbial communities (2014) (405)
- Accurate multiplex gene synthesis from programmable DNA microchips (2004) (394)
- Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation. (2003) (385)
- RNA expression analysis using a 30 base pair resolution Escherichia coli genome array (2000) (383)
- B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes (2014) (378)
- Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues (2015) (376)
- Meta’omic analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism (2019) (372)
- Optimization of scarless human stem cell genome editing (2013) (364)
- Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes (2000) (362)
- Composability of regulatory sequences controlling transcription and translation in Escherichia coli (2013) (357)
- A comprehensive library of DNA-binding site matrices for 55 proteins applied to the complete Escherichia coli K-12 genome. (1998) (357)
- Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors. (2002) (354)
- Genome-Scale Metabolic Model of Helicobacter pylori 26695 (2002) (351)
- Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K‐12 (1997) (344)
- Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach (2015) (340)
- The Isw2 Chromatin Remodeling Complex Represses Early Meiotic Genes upon Recruitment by Ume6p (2000) (334)
- Proteogenomic mapping as a complementary method to perform genome annotation (2004) (331)
- A global view of pleiotropy and phenotypically derived gene function in yeast (2005) (330)
- Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. (1978) (326)
- Ethical and Practical Guidelines for Reporting Genetic Research Results to Study Participants: Updated Guidelines from a National Heart, Lung, and Blood Institute Working Group (2010) (324)
- A highly annotated whole-genome sequence of a Korean individual (2009) (323)
- Nanotools for neuroscience and brain activity mapping. (2013) (320)
- Quantitative Morphological Signatures Define Local Signaling Networks Regulating Cell Morphology (2007) (319)
- Biocontainment of genetically modified organisms by synthetic protein design (2015) (316)
- Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip (2017) (316)
- Improving molecular cancer class discovery through sparse non-negative matrix factorization (2005) (315)
- pLogo: a probabilistic approach to visualizing sequence motifs (2013) (313)
- Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution (2007) (310)
- Computational and experimental identification of C. elegans microRNAs. (2003) (306)
- Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence. (2000) (294)
- Exploring the DNA-binding specificities of zinc fingers with DNA microarrays (2001) (293)
- Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. (2006) (291)
- The promise of organ and tissue preservation to transform medicine (2017) (291)
- Reprogramming of T cells from human peripheral blood. (2010) (288)
- Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform (2016) (288)
- Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx (2000) (287)
- Genome engineering (2009) (283)
- Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium (1993) (282)
- An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts. (2007) (282)
- Regulating gene drives (2014) (274)
- Reprogramming to recover youthful epigenetic information and restore vision (2020) (273)
- Safeguarding CRISPR-Cas9 gene drives in yeast (2015) (271)
- An enhanced CRISPR repressor for targeted mammalian gene regulation (2018) (269)
- Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range (2002) (269)
- A dynamic programming approach to de novo peptide sequencing via tandem mass spectrometry (2000) (267)
- The role of replicates for error mitigation in next-generation sequencing (2013) (265)
- Cas9 gRNA engineering for genome editing, activation and repression (2015) (262)
- Regulatory network of acid resistance genes in Escherichia coli (2003) (261)
- The challenges of sequencing by synthesis (2009) (260)
- Nanoscale Imaging of RNA with Expansion Microscopy (2016) (258)
- Insights into the Evolution of Longevity from the Bowhead Whale Genome (2015) (256)
- Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases (2010) (255)
- Cell-type-specific contacts to immunoglobulin enhancers in nuclei (1985) (253)
- In situ localized amplification and contact replication of many individual DNA molecules. (1999) (251)
- Automated modelling of signal transduction networks (2002) (249)
- Accurate whole genome sequencing and haplotyping from10-20 human cells (2012) (248)
- Comparative Analysis of Cas9 Activators Across Multiple Species (2016) (247)
- The complete genome and proteome of Mycoplasma mobile. (2004) (245)
- The Personal Genome Project (2005) (241)
- CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria (2017) (235)
- Safeguarding gene drive experiments in the laboratory (2015) (234)
- Evolution-guided optimization of biosynthetic pathways (2014) (233)
- Developmental barcoding of whole mouse via homing CRISPR (2018) (232)
- A structure-factor least-squares refinement procedure for macromolecular structures using constrained and restrained parameters (1977) (230)
- Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA. (2012) (229)
- Conservation of DNA regulatory motifs and discovery of new motifs in microbial genomes. (2000) (228)
- Engineering an allosteric transcription factor to respond to new ligands (2015) (227)
- Quantifying DNA–protein interactions by double-stranded DNA arrays (1999) (226)
- Genome-scale promoter engineering by Co-Selection MAGE (2012) (224)
- The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting. (2006) (220)
- Design, synthesis, and testing toward a 57-codon genome (2016) (220)
- Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues (2019) (214)
- Polony Multiplex Analysis of Gene Expression (PMAGE) in Mouse Hypertrophic Cardiomyopathy (2007) (211)
- The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. (2011) (210)
- Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips (2010) (209)
- Realizing the potential of synthetic biology (2014) (208)
- An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance (2018) (208)
- Autoantigen discovery with a synthetic human peptidome. (2011) (204)
- The Human Ageing Genomic Resources: online databases and tools for biogerontologists (2009) (200)
- Computational discovery of sense-antisense transcription in the human and mouse genomes (2002) (200)
- A public resource facilitating clinical use of genomes (2012) (197)
- Fluorescent in situ sequencing on polymerase colonies. (2003) (197)
- The Scientific Foundation for Personal Genomics: Recommendations from a National Institutes of Health–Centers for Disease Control and Prevention Multidisciplinary Workshop (2009) (196)
- Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers (2012) (195)
- The amino-acid mutational spectrum of human genetic disease (2003) (194)
- Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves (2012) (193)
- Physical principles for scalable neural recording (2013) (193)
- Forward Error Correction for DNA Data Storage (2016) (191)
- Lambda Red Recombineering in Escherichia coli Occurs Through a Fully Single-Stranded Intermediate (2010) (189)
- Rates, Distribution, and Implications of Post-zygotic Mosaic Mutations in Autism Spectrum Disorder (2017) (187)
- Low-N protein engineering with data-efficient deep learning (2020) (184)
- Daisy-chain gene drives for the alteration of local populations (2016) (183)
- The Brain Activity Map (2013) (182)
- Digital RNA Allelotyping Reveals Tissue-specific and Allele-specific Gene Expression in Human (2009) (181)
- The human microbiome harbors a diverse reservoir of antibiotic resistance genes (2010) (181)
- The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies (2013) (181)
- Alignment and structure prediction of divergent protein families: periplasmic and outer membrane proteins of bacterial efflux pumps. (1999) (178)
- Elevated Coding Mutation Rate During the Reprogramming of Human Somatic Cells into Induced Pluripotent Stem Cells (2012) (178)
- A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies (2006) (178)
- Rapidly evolving homing CRISPR barcodes (2016) (177)
- Synthetic biosensors for precise gene control and real-time monitoring of metabolites (2015) (176)
- Synthetic biology projects in vitro. (2006) (175)
- A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli. (2003) (174)
- Engineering life: building a fab for biology. (2006) (173)
- Biosensor-based engineering of biosynthetic pathways. (2016) (173)
- Multiplex DNA sequencing. (1988) (172)
- Nucleic acid memory. (2016) (172)
- A robust benchmark for detection of germline large deletions and insertions (2020) (171)
- Rapid neurogenesis through transcriptional activation in human stem cells (2014) (167)
- Systematic identification of edited microRNAs in the human brain (2012) (167)
- Molecular recordings by directed CRISPR spacer acquisition (2016) (166)
- Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design (2019) (166)
- RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe. (1977) (166)
- Escherichia coli Gene Expression Responsive to Levels of the Response Regulator EvgA (2002) (164)
- ‘Fit-for-purpose?’ – challenges and opportunities for applications of blockchain technology in the future of healthcare (2019) (162)
- High-resolution antibody dynamics of vaccine-induced immune responses (2014) (160)
- Large-scale identification of genetic design strategies using local search (2009) (160)
- Selection analyses of insertional mutants using subgenic-resolution arrays (2001) (160)
- The Genome Project-Write (2016) (158)
- Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites. (2005) (152)
- sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity. (2017) (152)
- Digital genotyping and haplotyping with polymerase colonies (2003) (152)
- Evolutionary dynamics of CRISPR gene drives (2016) (151)
- Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence (2011) (149)
- Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering. (2011) (148)
- PEPPeR, a Platform for Experimental Proteomic Pattern Recognition*S (2006) (148)
- Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells (2014) (146)
- Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability (2006) (145)
- Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems (2020) (144)
- Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification (2006) (142)
- Genetically encoded sensors enable real-time observation of metabolite production (2016) (142)
- Heritable Custom Genomic Modifications in Caenorhabditis elegans via a CRISPR–Cas9 System (2013) (140)
- Computation-based discovery of related transcriptional regulatory modules and motifs using an experimentally validated combinatorial model. (2002) (139)
- Genomes for all (2004) (139)
- Overview of DNA Sequencing Strategies (2011) (139)
- Yeast oligo-mediated genome engineering (YOGE). (2013) (136)
- Current CRISPR gene drive systems are likely to be highly invasive in wild populations (2017) (132)
- Localization to the Proteasome Is Sufficient for Degradation* (2004) (129)
- Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA) (2014) (128)
- In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation (2013) (128)
- Systematic management and analysis of yeast gene expression data. (2000) (128)
- A new dawn for industrial photosynthesis (2011) (127)
- A general strategy to construct small molecule biosensors in eukaryotes (2015) (125)
- Tools for the Microbiome: Nano and Beyond. (2015) (124)
- REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease (2019) (122)
- Codon usage of highly expressed genes affects proteome-wide translation efficiency (2018) (122)
- Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells (2014) (120)
- MapQuant: Open‐source software for large‐scale protein quantification (2006) (119)
- Probing the Limits of Genetic Recoding in Essential Genes (2013) (119)
- Deciphering the functions and regulation of brain-enriched A-to-I RNA editing (2013) (119)
- Barcoding bias in high-throughput multiplex sequencing of miRNA. (2011) (117)
- Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier. (2021) (117)
- Identifying metabolic enzymes with multiple types of association evidence (2006) (115)
- Filling gaps in a metabolic network using expression information (2004) (115)
- Regulation of Lifespan by Neural Excitation and REST (2019) (115)
- Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm. (2002) (114)
- DNA synthesis and biological security (2007) (113)
- Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array (2016) (112)
- Terminator-free template-independent enzymatic DNA synthesis for digital information storage (2019) (111)
- Single Molecule Profiling of Alternative Pre-mRNA Splicing (2003) (111)
- Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants (2006) (110)
- The ethics of experimenting with human brain tissue (2018) (110)
- Deep diversification of an AAV capsid protein by machine learning (2021) (108)
- A CRISPR Cas9-based gene drive platform for genetic interaction analysis in Candida albicans (2017) (108)
- Predicting Protein Post-translational Modifications Using Meta-analysis of Proteome Scale Data Sets*S (2009) (106)
- Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi (2019) (105)
- Cells discover fire: Employing reactive oxygen species in developmentand consequences for aging (2006) (105)
- Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures (2020) (101)
- Genomes optimize reproduction: aging as a consequence of the developmental program. (2005) (100)
- Dynamic simulation of the human red blood cell metabolic network (2001) (99)
- Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip (2018) (99)
- Efficient in situ barcode sequencing using padlock probe-based BaristaSeq (2017) (98)
- Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection (2012) (98)
- Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues. (2017) (97)
- Genomic Studies with Escherichia coli MelR Protein: Applications of Chromatin Immunoprecipitation and Microarrays (2004) (96)
- In situ genome sequencing resolves DNA sequence and structure in intact biological samples (2020) (95)
- Discovering functional transcription-factor combinations in the human cell cycle. (2005) (95)
- Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae. (2002) (95)
- An Integrated Strategy for Analyzing the Unique Developmental Programs of Different Myoblast Subtypes (2006) (94)
- Proteome-wide systems analysis of a cellulosic biofuel-producing microbe (2011) (94)
- RNA Sequencing Reveals Differential Expression of Mitochondrial and Oxidation Reduction Genes in the Long-Lived Naked Mole-Rat When Compared to Mice (2011) (93)
- Expression dynamics of a cellular metabolic network (2005) (93)
- Public Access to Genome-Wide Data: Five Views on Balancing Research with Privacy and Protection (2009) (92)
- Inter-homologue repair in fertilized human eggs? (2017) (92)
- Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus. (2003) (92)
- The Most Conserved Genome Segments for Life Detection on Earth and Other Planets (2008) (90)
- Essential genes as antimicrobial targets and cornerstones of synthetic biology. (2012) (90)
- Genome editing in human stem cells. (2014) (90)
- High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing. (2010) (89)
- Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli (1998) (89)
- Secondary structural complementarity between DNA and proteins. (1977) (89)
- Harvard Personal Genome Project: lessons from participatory public research (2014) (88)
- Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies (2016) (88)
- Chromosome-scale, haplotype-resolved assembly of human genomes (2020) (87)
- Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions (2020) (87)
- Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis. (2012) (87)
- Addressing the ethical issues raised by synthetic human entities with embryo-like features (2017) (86)
- Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367 (2009) (85)
- Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA Breaks. (2018) (84)
- Improving Lambda Red Genome Engineering in Escherichia coli via Rational Removal of Endogenous Nucleases (2012) (83)
- Genomic Analysis of the Hydrocarbon-Producing, Cellulolytic, Endophytic Fungus Ascocoryne sarcoides (2012) (83)
- Predicting regulons and their cis-regulatory motifs by comparative genomics. (2000) (82)
- Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. (2009) (82)
- Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks. (2002) (81)
- Long-range polony haplotyping of individual human chromosome molecules (2006) (80)
- A motif co-occurrence approach for genome-wide prediction of transcription-factor-binding sites in Escherichia coli. (2004) (78)
- 3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing. (2020) (77)
- Complementary recognition in condensed DNA: accelerated DNA renaturation. (1991) (77)
- Extensive germline genome engineering in pigs (2020) (76)
- Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura (2004) (74)
- A Deep Learning Approach to Antibiotic Discovery (2020) (74)
- Preferred in vivo ubiquitination sites (2004) (74)
- The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations (2014) (73)
- CRISPR/Cas9‐Directed Genome Editing of Cultured Cells (2014) (73)
- Transcriptional Profiling of CD4 T Cells Identifies Distinct Subgroups of HIV-1 Elite Controllers (2010) (73)
- PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. (2013) (73)
- CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomes (2014) (73)
- A comprehensive library of human transcription factors for cell fate engineering (2020) (72)
- A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion (2010) (71)
- High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR/Cas9 in yeast (2018) (70)
- From systems biology to synthetic biology (2005) (70)
- Quantification of microRNA Expression with Next‐Generation Sequencing (2013) (70)
- Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion (2011) (70)
- Chromosomal periodicity of evolutionarily conserved gene pairs (2007) (69)
- Recoding the genetic code with selenocysteine. (2014) (69)
- The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing (2020) (69)
- Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook (2019) (68)
- From annotated genomes to metabolic flux models and kinetic parameter fitting. (2003) (67)
- Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses (2021) (67)
- A Robust Approach to Identifying Tissue-Specific Gene Expression Regulatory Variants Using Personalized Human Induced Pluripotent Stem Cells (2009) (67)
- A whole genome approach to in vivo DNA-protein interactions in E. coli (1992) (67)
- Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing. (2015) (66)
- Pleiotropic mutations within two yeast mitochondrial cytochrome genes block mRNA processing (1979) (66)
- Multiplex single-molecule interaction profiling of DNA-barcoded proteins (2014) (66)
- Improved Cell-Free RNA and Protein Synthesis System (2014) (66)
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- Gene Assembly from Chip-Synthesized (2012) (2)
- Establishing a cell-free Vibrio natriegens expression system (2018) (2)
- A robust benchmark for detection of germline large deletions and insertions (2020) (2)
- Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability (2023) (2)
- Corrigendum: An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes (2017) (2)
- Barcoding cells using cell-surface programmable (2013) (2)
- Tuberculosis Drug Resistance Mutation (2009) (2)
- Efficient modification and preparation of circular DNA for expression in cell culture (2022) (2)
- Back to the future: From genome to metabolome (2012) (2)
- In vivo multi-dimensional information-keeping in Halobacterium salinarum (2020) (2)
- Physiological assembly of functionally active 30S ribosomal subunits from in vitro synthesized parts (2017) (2)
- CRISPR / Cas 9-Mediated Phage Resistance Is Not Impeded by the DNA Modifications of Phage T 4 (2014) (1)
- How to grow (almost) anything: a hybrid distance learning model for global laboratory-based synthetic biology education. (2022) (1)
- Reconstruction of the gastric cancer microenvironment after neoadjuvant chemotherapy by longitudinal single-cell sequencing (2022) (1)
- High dose systemic gene therapy: emerging trends on safety and efficacy (2020) (1)
- Engineering life: Building a FAB for Biology. (Cover story) (2006) (1)
- Reading and writing genomes (2010) (1)
- The inherent challenges of classifying senescence—Response (2020) (1)
- A Practical Perspective on DNA Synthesis and Biological Security (12/4/2006 Draft) (2006) (1)
- Genomics is mired in misunderstanding (2013) (1)
- Transcriptional Profiling of CD4 T Cells Identifies Distinct Subgroups of HIV-1 Elite Controllers (cid:1) † (2011) (1)
- Genome Accurate Multiplex Polony Sequencing of an Evolved Bacterial (2012) (1)
- Picogram-Scale Interstellar Probes via Bioinspired Engineering (2022) (1)
- Multiplex Single-Molecule Kinetics of Nanopore-Coupled Polymerases. (2020) (1)
- On the design of clone-based haplotyping (2013) (1)
- STAMPScreen: An Integrated Pipeline for Mammalian Genetic Screening (2021) (1)
- Results of a 5 year N-of-1 GHRH gene therapy experiment. (2021) (1)
- Multi-pronged human protein mimicry by SARS-CoV-2 reveals bifurcating potential for MHC detection and immune evasion (2020) (1)
- How accurate can genetic predictions be? (2012) (1)
- Abstract 6070: Functional natural killer cells derived from engineered hiPSC with hypoimmunity gene combo demonstrate hypoimmunity features in evading host attacks (2022) (1)
- Chapter 1 Recent Progress in Engineering Human-Associated Microbiomes (2014) (1)
- DNA SEQUENCING BY LIGATION ON SURFACE- BOUND BEADS IN A MICROCHANNEL ENVIRONMENT (2008) (1)
- A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules (2022) (1)
- Correction for Davidsohn et al., A single combination gene therapy treats multiple age-related diseases (2019) (1)
- Author Correction: A robust benchmark for detection of germline large deletions and insertions (2020) (1)
- Monitoring Imatinib Resistance with a “Polony” Assay: Towards Tailored Therapy of Chronic Myelogenous Leukemia (CML). (2006) (1)
- Clustering cell types and identifying cell-type specific transcripts by gene expression profiling in single neurons (1999) (1)
- A BioBrick compatible strategy for genetic modification of plants (2012) (1)
- Comparison of Extracellular Vesicle Isolation Methods from Human Biofluids using Single Molecule Arrays (2020) (1)
- Why it is important to study human–monkey embryonic chimeras in a dish (2022) (1)
- The Brain Activity Map and Functional Connectomics (2012) (1)
- Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy (2020) (1)
- The Whole Brain Activity Map: Merging Nanoscience and Neuroscience for Technology and Health (2011) (1)
- Engineering post-translational proofreading to discriminate non-standard amino acids (2017) (1)
- Correction: Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression (2023) (1)
- Genes drive organisms and slippery slopes. (2022) (1)
- Corrigendum: Engineering and optimising deaminase fusions for genome editing (2017) (1)
- Efficient Human Germ Cell Specification from Stem Cells via Combinatorial Expression of Transcription Factors (2022) (1)
- Supplemental Data Relationships between p 63 Binding , DNA Sequence , Transcription Activity , and Biological Function in Human Cells (2006) (1)
- Characterization of ColE1 Production for Robust tolC Plate Dual-Selection in E. coli (2022) (1)
- Harvard Personal Genome Project: lessons from participatory public research (2014) (1)
- One-Seq: A Highly Scalable Sequencing-Based Diagnostic for SARS-CoV-2 and Other Single-Stranded Viruses (2021) (1)
- Discovery of DNA Regulatory Motifs (2002) (1)
- Multiplex single-molecule kinetics of nanopore-coupled polymerases (2020) (1)
- Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing † Integrative Biology (2015) (0)
- hypermutable CpG variations Multiplex padlock targeted sequencing reveals human Material (2009) (0)
- Thirty-Eight Special: George Church Pushes the Biotech Envelope (2022) (0)
- iNGN iPS Cell Differentiation to Neurons for Extracellular Vesicle Isolation v1 (2020) (0)
- Construction and evolution of an artificial microbial symbiotic system (2005) (0)
- Genome-Scale Promoter Engineering by Coselection MAGE The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2012) (0)
- ABLC Forum: Aspirations for a Fragile Planet (2021) (0)
- Supporting Online Material for Local Signaling Networks That Regulate Cell Morphology Defined by Quantitative Morphological Signatures (2007) (0)
- Lac repressor engineered to bind sucralose, unliganded tetramer (2015) (0)
- Chinese scientists and US leadership in the life sciences (2019) (0)
- Parallel and sequential reactor (1992) (0)
- Genome interpretation and assembly-recent progress and next steps. (2012) (0)
- Proposal for a “Next-Generation” Scientific Publication System (2018) (0)
- Explorer Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells (2017) (0)
- Ingenierie des genomes guidee par arn multiplex (2014) (0)
- Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity. (2023) (0)
- Genomic Sequence Comparisons, 1987-2003 Final Report (2004) (0)
- Preparation of CRISPR/Cas9 and gRNA plasmids (2016) (0)
- Transcriptomic reprogramming for neuronal age reversal (2023) (0)
- Reliable multiplex generation of pooled induced pluripotent stem cells for genetic testing (2022) (0)
- High-throughput fluorescent sequencing of biomolecules within their cellular environment (2020) (0)
- Applications of Genome Editing in Humans and Wild Species (2017) (0)
- Clinical DNA Sequencer for Ultra-Low Cost Testing (2012) (0)
- Surface attachment chemistry for in situ probe DNA amplification (1999) (0)
- Strategies to Identify and Edit Improvements in Synthetic Genome Segments Episomally (2022) (0)
- Mitigating age-related somatic mutation burden. (2023) (0)
- oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids. (2023) (0)
- Abstract 3155: "Super NK cells" - natural killer cells derived from engineered hiPSC with enhanced NK receptor expression demonstrate better anti-tumor effects for solid tumors (2022) (0)
- A Call for a Three-Tiered Pandemic Public Health Strategy in Context of SARS-CoV-2 (2020) (0)
- First Rounders: George Church (2019) (0)
- Swapped genetic code blocks viral infections and gene transfer (2022) (0)
- Title : High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR / Cas 9 (2017) (0)
- Publisher Correction: Single-sequence protein structure prediction using a language model and deep learning (2022) (0)
- Proposal for a Center for the determination of the Causal Transcriptional Consequences of Human (2009) (0)
- Rapidly evolving homing CRISPR barcodes The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2017) (0)
- METHODS OF GENETIC MODIFICATION OF A CELL (2018) (0)
- An Interpretable Deep Embedding Model for Few and Imbalanced Biomedical Data. (2022) (0)
- The ethics of experimenting with human brain tissue (2018) (0)
- Neural Circuit Mapping Project—The Functional Connectome (2011) (0)
- Machine-guided cell-fate engineering (2023) (0)
- Expansion Sequencing of RNA Barcoded Neurons in the Mammalian Brain: Progress and Implications for Molecularly Annotated Connectomics (2022) (0)
- Complete mitochondrial genomes of living and extinct pigeons revise the timing of the columbiform radiation (2016) (0)
- Accommodation or prediction? [2] (multiple letters) (2005) (0)
- Expanding Homogeneous Culture of Human Primordial Germ Cell–Like Cells Maintaining Germline Features Without Serum or Feeder Layers (2022) (0)
- Direct of thousands of genomic targets using microarray-derived oligonucleotides. (2015) (0)
- A Model for Recognition Scheme between Double Stranded DNA and Proteins (0)
- Experimental and theoretical studies of artificial microbial symbiosis (2004) (0)
- Multiple haplotype-resolved genomes reveal population level gene and protein diplotype patterns (2015) (0)
- Processive template independent dna polymerase variants (2017) (0)
- Methods of genome engineering by nuclease-transposase fusion proteins (2018) (0)
- SequencesStatistical Tests for Detecting Selection in Ig Integrating B Cell Lineage Information into (2013) (0)
- Human Subjects: E4-human Subjects Involved -exemption #4 Designated Animal Subjects: 30-animals Involved -no Srg Comments or Concerns Noted Children: 4a-child Representation Unknown,scientifically Acceptable Clinical Research -not Nih-defined Phase Iii Trial Project Year 1 2 3 4 5 ___________ Total (0)
- Nucleotide-time alignment for molecular recorders (2017) (0)
- Next-generation carrier screening The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2014) (0)
- Publisher Correction: Voices of biotech leaders (2021) (0)
- Quantitative isoform profiling and isoform convergence (2005) (0)
- Title: helixCAM: A Platform for Programmable Cellular Assembly in Bacteria and Human Cells (2022) (0)
- TARGETING MICROBIAL COMMUNITIES FOR FORWARD ENGINEERING (2013) (0)
- Computer assisted multiplex sequencing (1992) (0)
- Data integration of bulk and single-cell transcriptomics from cerebral organoids and post-mortem brains to identify cell types and cell type specific driver genes in autism (2020) (0)
- Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues (2022) (0)
- Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine (2015) (0)
- P4) Technologies for Reading and Writing Omes. (2012) (0)
- Improved Isolation of Extracellular Vesicles by Removal of Both Free Proteins and Lipoproteins (2023) (0)
- Multiplex-rna-gesteuertes genom-engineering (2014) (0)
- More Haemophilus and Mycoplasma Genes (1996) (0)
- A new milp based approach for in silico reconstruction of metabolic networks and its application to marine cyanobacterium prochlorococcus marinus (2005) (0)
- Comprehensive mutagenesis maps the effect of all single codon mutations in the AAV2 rep gene on AAV production (2023) (0)
- Method of off-target recording of spacer sequences within a cell in vivo (2018) (0)
- Miniaturized, high-density, bead-based arrays are provided. Methods of producing and using clonal beads and producing and using miniaturized, high density, bead-based arrays are also provided. (2008) (0)
- Nanoscale Imaging of RNA with Expansion Microscopy this access benefits you. Your story matters (2016) (0)
- Cleavable nucleotide analogs and uses thereof (2017) (0)
- An enhanced CRISPR repressor for targeted mammalian gene regulation (2018) (0)
- Alexander Fleming Invented penicillin on bacterial pain ngs on papers and petri dishes Edward Steichen Conceived the idea of gene c art with mutant plants (2015) (0)
- Publisher Correction: Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder (2020) (0)
- Author Correction: Data privacy in the age of personal genomics (2019) (0)
- Enabling multiplexed testing of pooled donor cells through whole-genome sequencing (2018) (0)
- Evolved Bacterial Genome Accurate Multiplex Polony Sequencing of an (2010) (0)
- Perturbation of Gene Regulation by Genome Editing. (2023) (0)
- Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC (2022) (0)
- Proposal to Sequence an Organism of Unique Interest for Research on Aging : Heterocephalus glaber , the Naked Mole-Rat (2008) (0)
- Technologies for Reading, Writing & Editing Omes. (2020) (0)
- Methods of regulating gene expression in a cell (2018) (0)
- Multiplex CRISPR strategy targeting viral genome for agriculture and clinical use (2022) (0)
- Molecular Cloning of Green Fluorescent Protein in Escherichia coli (2013) (0)
- 656 A computational approach to understanding rosacea, acne, and hidradenitis suppurativa (2021) (0)
- Saccharomyces cerevisiae-Regulatory Cassette of rRNA Transcription Motifs in cis Genome-wide Co-occurrence of Promoter Elements Reveals a (2002) (0)
- THIS DOCUMENT IS NO LONGER ACTIVE Challenges and Opportunities for Writing Genomes (0)
- Light and carbon: Synthetic biology toward new cyanobacteria-based living biomaterials (2023) (0)
- Technologies for Reading, Writing & Editing Omes. (2020) (0)
- Thoughts on the Manchester Manifesto (2011) (0)
- Genome Editing With Targeted Deaminases (2016) (0)
- Secondary structural complementarity between DNA and proteins ( DNA-protein interaction / fl-ribbon / DNA minor groove ) (0)
- SÉQUENÇAGE FLUORESCENCE IN SITU D'EXPANSION CIBLÉE (2018) (0)
- Delivery of biomacromolecules for therapeutic genome editing. (2021) (0)
- Lac repressor engineered to bind sucralose, sucralose-bound tetramer (2015) (0)
- The future of human nature: a symposium on the promises and challengesof the revolutions in genomics and computer science, April 10, 11, and 12, 2003 (2004) (0)
- Editing the Human Genome: Progress and Controversies (2017) (0)
- Dispositifs d'origami d'adn (2011) (0)
- Engineered guide rna sequences for in situ detection and sequencing (2017) (0)
- Supplementary Materials for Genomically Recoded Organisms Expand Biological Functions (2013) (0)
- Gem of an idea for a unique machine. (2007) (0)
- Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency (2021) (0)
- Evolved Bacterial Genome Accurate Multiplex Polony (2008) (0)
- Optimizing complex phenotypes through model-guided multiplex genome engineering (2017) (0)
- PGP1 personal genome assembly - a hybrid assembly dataset using ONT’s PromethION and PacBio’s HiFi sequencing (2021) (0)
- Tetraspanin (CD9, CD63, CD81) Western Blot for Extracellular Vesicles v1 (2020) (0)
- Publisher Correction: DNA sequencing at 40: past, present and future (2019) (0)
- Synthetic auxotrophy remains stable after continuous evolution and in co-culture with mammalian cells (2020) (0)
- Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration (2018) (0)
- Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures (2020) (0)
- Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi (2019) (0)
- Characterization of individual polymer molecules by monomer-interfacial-interaction (1996) (0)
- ProPeL: A method to discover specific kinase motifs and predict target substrates (2013) (0)
- Methods of making proteins with non-standard amino acids (2018) (0)
- Modulation of enzymatic polynucleotide synthesis using chelated divalent cations (2017) (0)
- Designing Vaccines and Biologics to Minimize Antibody-Dependent Enhancement of Viral Infections (2020) (0)
- Rapid Deployment Vaccine Collaborative (RaDVaC) (0)
- A swapped genetic code prevents viral infections and gene transfer (2023) (0)
- Dissecting human diploidy: Results from up to 1092 genomes (2015) (0)
- Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium (2019) (0)
- An interactive and probabilistic strategy for visualizing linear biological sequence motifs (2013) (0)
- Proposal to Sequence Genomes of Unique Interest for Research on Aging: Heterocephalus glaber, Cebus capucinus, and Balaena mysticetus (2007) (0)
- Millstone: software for multiplex microbial genome analysis and engineering (2017) (0)
- Accurate high-throughput gene synthesis using programmable microfluidic DNA microchips (2005) (0)
- Erratum to “Fluorescent in situ sequencing on polymerase colonies” [Anal. Biochem. 320 (2003) 55–65] (2004) (0)
- Methods of crispr mediated genome modulation in v. natriegens (2017) (0)
- A robust benchmark for germline large deletion and insertion detection (0)
- Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions (2020) (0)
- Science Journals — AAAS (2016) (0)
- Saccharomyces cerevisiae A network of transcriptionally coordinated functional modules in data (2005) (0)
- Isaacs Genome-Wide Codon Replacement Precise Manipulation of Chromosomes in Vivo Enables (2011) (0)
- Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators (2018) (0)
- Hunger for new technologies, metrics, and spatiotemporal models in functional genomic (abstract only) (2001) (0)
- Ethnically relevant consensus Korean reference genome towards personal reference genomes (2016) (0)
- PAM-Flexible Genome Editing with an Engineered Chimeric Cas9 (2023) (0)
- Computer assisted multiplex sequencing. Progress report, August 1, 1991--July 31, 1992 (1992) (0)
- Title Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells (2015) (0)
- Systemic post-translational control of bacterial metabolism 1 regulates adaptation in dynamic environments Metabolic regulation can be predicted in genome-scale models modifications on metabolic regulation (2017) (0)
- Introduction Characterization of Cas 9 – Guide RNA Orthologs (2016) (0)
- The Advent of Human Life Data Economics: (Trends in Molecular Medicine 25, 566-570; 2019). (2019) (0)
- Caracterisation de molecules de polymere particulieres sur la base des interactions monomeres-interface (1996) (0)
- High-throughput single-cell PCR using microfluidic emulsions (2012) (0)
- The present invention relates to automated methods of introducing multiple nucleic acid sequences into one or more target cells. (2012) (0)
- PDB_ISL: an intermediate sequence library for protein structure assignment (2000) (0)
- Single-Molecule Characterization of a Nanopore-Coupled Cas9 Protein on an Electrode Array (2018) (0)
- Free factories: from the quantum coreworld to the personal genome project (2009) (0)
- Recording temporal data with minutes resolution into DNA (2019) (0)
- Voices of biotech leaders (2021) (0)
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