George Q. Daley | Academic Influence

George Q. Daley's AcademicInfluence.com Rankings

George Q. Daley

Medical

#119

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#190

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Pharmacology

#39

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#54

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George Q. Daley

Philosophy

#3417

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#5533

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#1146

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#1820

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Medical
Philosophy

George Q. Daley's Degrees

Doctorate Medicine Harvard University

Why Is George Q. Daley Influential?

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According to Wikipedia, George Quentin Daley is the Dean of the Faculty of Medicine, Caroline Shields Walker Professor of Medicine, and Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. He was formerly the Robert A. Stranahan Professor of Pediatrics at Harvard Medical School, Director of the Stem Cell Transplantation Program at Boston Children's Hospital, and an investigator of the Howard Hughes Medical Institute, Associate Director of Children's Stem Cell Program, a member of the Executive Committee of the Harvard Stem Cell Institute. He is a past president of the International Society for Stem Cell Research .

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George Q. Daley's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Reprogramming of human somatic cells to pluripotency with defined factors (2008) (2891)
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. (2010) (2537)
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. (1990) (2241)
Disease-Specific Induced Pluripotent Stem Cells (2008) (2194)
Epigenetic memory in induced pluripotent stem cells (2010) (2191)
Selective Blockade of MicroRNA Processing by Lin28 (2008) (1477)
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. (2005) (1471)
Somatic coding mutations in human induced pluripotent stem cells (2011) (1218)
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts (2009) (1174)
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis (2007) (1084)
The promise of induced pluripotent stem cells in research and therapy (2012) (1073)
Bone marrow adipocytes as negative regulators of the hematopoietic microenvironment (2009) (949)
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells (2010) (921)
Derivation of embryonic germ cells and male gametes from embryonic stem cells (2004) (862)
The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. (1986) (839)
HoxB4 Confers Definitive Lymphoid-Myeloid Engraftment Potential on Embryonic Stem Cell and Yolk Sac Hematopoietic Progenitors (2002) (805)
The Lin28/let-7 Axis Regulates Glucose Metabolism (2011) (802)
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells (2011) (762)
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. (2011) (735)
Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration (2009) (671)
Corrigendum: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells (2009) (637)
Mechanisms of Autoinhibition and STI-571/Imatinib Resistance Revealed by Mutagenesis of BCR-ABL (2003) (634)
A comprehensive methylome map of lineage commitment from hematopoietic progenitors (2010) (626)
Chromatin modifying enzymes as modulators of reprogramming (2012) (621)
Generation of induced pluripotent stem cells from human blood. (2009) (619)
Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy (2002) (614)
Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein. (1988) (600)
Characterization of single-nucleotide polymorphisms in coding regions of human genes (1999) (581)
SARS-CoV-2 viral load is associated with increased disease severity and mortality (2020) (576)
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (2011) (569)
A prudent path forward for genomic engineering and germline gene modification (2015) (565)
The P190, P210, and P230 Forms of the BCR/ABL Oncogene Induce a Similar Chronic Myeloid Leukemia–like Syndrome in Mice but Have Different Lymphoid Leukemogenic Activity (1999) (540)
The Toughest Triage - Allocating Ventilators in a Pandemic. (2020) (538)
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. (2009) (534)
Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors (2010) (528)
Human embryonic stem cells (2004) (521)
Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation (2013) (517)
Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells (2009) (506)
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming (2009) (505)
Stem cell metabolism in tissue development and aging (2013) (500)
LIF/STAT3 Signaling Fails to Maintain Self‐Renewal of Human Embryonic Stem Cells (2004) (494)
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (2011) (489)
Biomechanical forces promote embryonic haematopoiesis (2009) (472)
Characterization of single-nucleotide polymorphisms in coding regions of human genes (1999) (467)
Induced pluripotent stem cells — opportunities for disease modelling and drug discovery (2011) (460)
Generation of human-induced pluripotent stem cells (2008) (457)
CellNet: Network Biology Applied to Stem Cell Engineering (2014) (453)
Generation of functional human hepatic endoderm from human induced pluripotent stem cells (2009) (446)
Targeted and genome-scale methylomics reveals gene body signatures in human cell lines (2009) (434)
Lin28: primal regulator of growth and metabolism in stem cells. (2013) (419)
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. (2010) (403)
Lin28: A MicroRNA Regulator with a Macro Role (2010) (402)
Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. (2012) (402)
A comparison of non-integrating reprogramming methods (2014) (397)
Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers (2000) (394)
Activation of tyrosine kinases by mutation of the gatekeeper threonine (2008) (384)
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells (2011) (367)
Optimization of scarless human stem cell genome editing (2013) (364)
A role for Lin28 in primordial germ cell development and germ cell malignancy (2009) (363)
Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems. (2002) (357)
Haematopoietic stem and progenitor cells from human pluripotent stem cells (2017) (353)
Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28* (2008) (351)
Lin28 Enhances Tumorigenesis and is Associated With Advanced Human Malignancies (2009) (349)
Functional Evidence that the Self‐Renewal Gene NANOG Regulates Human Tumor Development (2009) (340)
Deconstructing transcriptional heterogeneity in pluripotent stem cells (2014) (335)
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia (2010) (331)
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability (2012) (326)
Hallmarks of pluripotency (2015) (322)
Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients (2009) (321)
Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice (2010) (304)
Prospects for Stem Cell-Based Therapy (2008) (304)
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies (2010) (298)
Origins and implications of pluripotent stem cell variability and heterogeneity (2013) (295)
Lineage Regulators Direct BMP and Wnt Pathways to Cell-Specific Programs during Differentiation and Regeneration (2011) (292)
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells (2012) (289)
Lin28 Enhances Tissue Repair by Reprogramming Cellular Metabolism (2013) (289)
Reprogramming of T cells from human peripheral blood. (2010) (288)
Induced pluripotent stem cells in disease modelling and drug discovery (2019) (288)
Down syndrome suppression of tumor growth and the role of the calcineurin inhibitor DSCR1 (2009) (287)
Single Nucleotide Polymorphisms in Multiple Novel Thrombospondin Genes May Be Associated With Familial Premature Myocardial Infarction (2001) (287)
High‐Efficiency RNA Interference in Human Embryonic Stem Cells (2005) (278)
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes (2003) (272)
Overcoming STI571 resistance with the farnesyl transferase inhibitor SCH66336. (2002) (270)
Alternative 5′ exons in c-abl mRNA (1986) (247)
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. (2013) (246)
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. (2016) (244)
Use of differentiated pluripotent stem cells in replacement therapy for treating disease (2014) (242)
Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet (2014) (239)
The promise and perils of stem cell therapeutics. (2012) (235)
New ISSCR guidelines underscore major principles for responsible translational stem cell research. (2008) (230)
Induced pluripotent stem cells for neural tissue engineering. (2011) (224)
Embryonic stem cell-derived hematopoietic stem cells. (2005) (220)
Therapeutic potential of embryonic stem cells. (2005) (219)
BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway. (2008) (218)
Histocompatible Embryonic Stem Cells by Parthenogenesis (2007) (214)
Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity (2010) (213)
Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants (1991) (202)
Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia. (2001) (201)
Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival (2011) (198)
Mechanisms and implications of imatinib resistance mutations in BCR-ABL (2004) (195)
Polycomb Repressive Complex 2 Regulates Normal Development of the Mouse Heart (2012) (191)
Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency (2015) (187)
The transcriptional landscape of hematopoietic stem cell ontogeny. (2012) (178)
Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient‐Derived Induced Pluripotent Stem Cells (2012) (175)
Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines (2016) (174)
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. (2007) (172)
Reprogramming Cellular Identity for Regenerative Medicine (2012) (168)
Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models. (2014) (168)
Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. (2007) (165)
Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma (2016) (162)
Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer. (2007) (161)
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos (2008) (159)
Nuclear transplantation, embryonic stem cells and the potential for cell therapy. (2003) (158)
Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells (2015) (157)
A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling. (2002) (155)
Lin28 sustains early renal progenitors and induces Wilms tumor (2014) (151)
The CML-specific P210 bcr/abl protein, unlike v-abl, does not transform NIH/3T3 fibroblasts. (1987) (146)
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions (2005) (145)
Overcoming reprogramming resistance of Fanconi anemia cells. (2012) (140)
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. (2015) (139)
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity (2011) (137)
Molecular basis of pluripotency. (2008) (132)
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. (2008) (130)
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity (2011) (129)
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells (2011) (129)
Secondary mutation maintains the transformed state in BaF3 cells with inducible BCR/ABL expression. (1998) (129)
Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 transgenic mice with the farnesyl transferase inhibitor SCH66336. (2001) (129)
From fibroblasts to iPS cells: Induced pluripotency by defined factors (2008) (128)
Reprogrammed cells for disease modeling and regenerative medicine. (2013) (127)
Blast crisis in a murine model of chronic myelogenous leukemia. (1991) (126)
Broader implications of defining standards for the pluripotency of iPSCs. (2009) (126)
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. (2009) (125)
Musashi-2 controls cell fate, lineage bias, and TGF-β signaling in HSCs (2014) (124)
Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential. (2001) (120)
Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome. (1986) (119)
Stem Cells in the Treatment of Disease. (2019) (118)
A blueprint for engineering cell fate: current technologies to reprogram cell identity (2013) (116)
Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling. (2004) (116)
Fetal Deficiency of Lin28 Programs Life‐Long Aberrations in Growth and Glucose Metabolism (2013) (114)
Cross-regulation of the Nanog and Cdx2 promoters (2009) (112)
Hematopoietic Development from Human Induced Pluripotent Stem Cells (2009) (111)
A functional screen identifies hDRIL1 as an oncogene that rescues RAS-induced senescence (2002) (110)
Investigating monogenic and complex diseases with pluripotent stem cells (2011) (109)
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity. (2014) (108)
Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration. (2017) (107)
Leukemia inhibitory factor (LIF) concentration modulates embryonic stem cell self-renewal and differentiation independently of proliferation. (2000) (106)
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. (2010) (104)
Dynamic instability of genomic methylation patterns in pluripotent stem cells (2010) (104)
Cooperative and redundant effects of STAT5 and Ras signaling in BCR/ABL transformed hematopoietic cells (2001) (104)
Confronting stem cell hype (2016) (104)
Human embryonic stem cell derivation from poor-quality embryos (2008) (100)
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance. (2006) (100)
Accessing naïve human pluripotency. (2012) (100)
The ISSCR Guidelines for Human Embryonic Stem Cell Research (2007) (99)
The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha. (1999) (98)
De novo generation of HSCs from somatic and pluripotent stem cell sources. (2015) (98)
Epoxyeicosatrienoic Acids Enhance Embryonic Haematopoiesis and Adult Marrow Engraftment (2015) (98)
Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells. (2014) (98)
Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). (2011) (97)
Molecular basis of the first cell fate determination in mouse embryogenesis (2010) (97)
Cell cycle adaptations of embryonic stem cells (2011) (97)
Induced pluripotent stem cell models from X‐linked adrenoleukodystrophy patients (2011) (94)
In vitro generation of germ cells from murine embryonic stem cells (2006) (94)
Realistic prospects for stem cell therapeutics. (2003) (94)
NF-κB activation impairs somatic cell reprogramming in ageing (2015) (93)
Novel role for PDEF in epithelial cell migration and invasion. (2005) (93)
LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans (2015) (92)
Regulation of stem cell therapies under attack in Europe: for whom the bell tolls (2013) (91)
Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient. (2012) (90)
Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors (2017) (89)
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. (2012) (89)
Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5 (2003) (88)
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. (2010) (88)
Induced Pluripotent Stem Cells with a Mitochondrial DNA Deletion (2013) (88)
Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production (2016) (87)
Chronic myeloid leukemia: reminiscences and dreams (2016) (87)
Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia. (1991) (86)
Hematopoietic Remodeling in Interferon-γ–Deficient Mice Infected With Mycobacteria (1998) (85)
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model (2006) (85)
Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation (2005) (85)
Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells (2013) (84)
Control of hematopoietic differentiation: lack of specificity in signaling by cytokine receptors. (1998) (83)
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021) (82)
Induced pluripotent stem cells for modelling human diseases (2011) (80)
Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates. (2012) (80)
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence (2015) (79)
microRNA Expression during Trophectoderm Specification (2009) (79)
Reconstruction of complex single-cell trajectories using CellRouter (2018) (77)
Engineering Hematopoietic Stem Cells: Lessons from Development. (2016) (77)
New lessons learned from disease modeling with induced pluripotent stem cells. (2012) (77)
The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming (2014) (76)
Common themes of dedifferentiation in somatic cell reprogramming and cancer. (2008) (76)
Taking stock and planning for the next decade: Realistic prospects for stem cell therapies for the nervous system (2004) (75)
A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth (2004) (75)
Stem cells: roadmap to the clinic. (2010) (75)
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction. (2013) (74)
Cdx gene deficiency compromises embryonic hematopoiesis in the mouse (2008) (73)
Altered nuclear transfer in stem-cell research - a flawed proposal. (2004) (73)
Metabolic switches linked to pluripotency and embryonic stem cell differentiation. (2015) (72)
The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation. (2005) (72)
A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts (2000) (71)
Biomechanical forces promote blood development through prostaglandin E2 and the cAMP–PKA signaling axis (2015) (70)
Progress towards generation of human haematopoietic stem cells (2016) (68)
Gametes from Embryonic Stem Cells: A Cup Half Empty or Half Full? (2007) (67)
Stem cells and their niche: a matter of fate (2006) (67)
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma (2016) (67)
A Robust Approach to Identifying Tissue-Specific Gene Expression Regulatory Variants Using Personalized Human Induced Pluripotent Stem Cells (2009) (67)
Pilot study of lonafarnib, a farnesyl transferase inhibitor, in patients with chronic myeloid leukemia in the chronic or accelerated phase that is resistant or refractory to imatinib therapy (2006) (66)
Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition (2012) (66)
Upping the ante: recent advances in direct reprogramming. (2009) (65)
Developmental regulation of myeloerythroid progenitor function by the Lin28b–let-7–Hmga2 axis (2016) (64)
Hematopoiesis from embryonic stem cells: lessons from and for ontogeny. (2003) (63)
Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells. (2002) (63)
From Embryos to Embryoid Bodies (2003) (62)
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. (2015) (62)
Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models. (2004) (62)
Autologous blood cell therapies from pluripotent stem cells. (2010) (61)
All-Trans Retinoic Acid Directs Urothelial Specification of Murine Embryonic Stem Cells via GATA4/6 Signaling Mechanisms (2010) (61)
Therapeutic Potential of Human Induced Pluripotent Stem Cells in Experimental Stroke (2013) (61)
Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival (2012) (60)
Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28 (2018) (58)
Expression of interferon consensus sequence binding protein induces potent immunity against BCR/ABL-induced leukemia. (2001) (58)
LIN28 phosphorylation by MAPK/ERK couples signaling to the post-transcriptional control of pluripotency (2016) (57)
Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line (1992) (56)
New ISSCR guidelines: clinical translation of stem cell research (2016) (56)
Effect of developmental stage of HSC and recipient on transplant outcomes. (2014) (55)
Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells. (2013) (54)
Phase 1 study of lonafarnib (SCH 66336) and imatinib mesylate in patients with chronic myeloid leukemia who have failed prior single‐agent therapy with imatinib (2007) (54)
Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes. (2008) (54)
Autocrine and paracrine effects of an ES-cell derived, BCR/ABL-transformed hematopoietic cell line that induces leukemia in mice (2001) (53)
Derivation and maintenance of human embryonic stem cells from poor-quality in vitro fertilization embryos (2008) (53)
Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence (2015) (52)
Acceleration of mesoderm development and expansion of hematopoietic progenitors in differentiating ES cells by the mouse Mix-like homeodomain transcription factor. (2006) (52)
Deciphering the rules of ceRNA networks (2013) (50)
Stem cells and the evolving notion of cellular identity (2015) (50)
Regulation of haematopoietic multipotency by EZH1 (2017) (50)
Lin28a Regulates Germ Cell Pool Size and Fertility (2013) (49)
Interactions between Cdx genes and retinoic acid modulate early cardiogenesis. (2011) (49)
A Role for Thrombopoietin in Hemangioblast Development (2003) (49)
Precise let-7 expression levels balance organ regeneration against tumor suppression (2015) (48)
YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. (2020) (48)
After the Storm - A Responsible Path for Genome Editing. (2019) (48)
Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling. (2017) (48)
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions (2012) (47)
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium. (2015) (47)
Sex-specific regulation of weight and puberty by the Lin28/let-7 axis. (2016) (46)
Policy: Global standards for stem-cell research (2016) (46)
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target (2020) (46)
Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2 (2021) (46)
Hematopoietic remodeling in interferon-gamma-deficient mice infected with mycobacteria. (1998) (45)
Induced pluripotent stem cells: a novel frontier in the study of human primary immunodeficiencies. (2011) (44)
Progress and prospects: gene transfer into embryonic stem cells (2006) (44)
The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program. (2019) (43)
Mesodermal patterning activity of SCL. (2008) (42)
v-abl causes hematopoietic disease distinct from that caused by bcr-abl. (1991) (42)
RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming. (2016) (42)
Failure to replicate the STAP cell phenomenon (2015) (42)
Hemogenic Endothelial Progenitor Cells Isolated from Human Umbilical Cord Blood (2007) (41)
9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation. (2009) (40)
Interaction of retinoic acid and scl controls primitive blood development. (2010) (40)
Inducible transgene expression in mouse stem cells. (2005) (40)
The heart SNPs a beat: polymorphisms in candidate genes for cardiovascular disease. (2001) (40)
Mining for SNPs: putting the common variants--common disease hypothesis to the test. (2000) (39)
Polar Extremes in the Clinical Use of Stem Cells. (2017) (39)
Overcoming STI 571 resistance with the farnesyl transferase inhibitor SCH 66336 (2002) (38)
The Cdx‐Hox Pathway in Hematopoietic Stem Cell Formation from Embryonic Stem Cells (2007) (38)
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis (2019) (38)
Genomic approaches to deconstruct pluripotency. (2011) (38)
Novel retroviral vectors to facilitate expression screens in mammalian cells. (2002) (37)
A nontranscriptional role for Oct4 in the regulation of mitotic entry (2014) (37)
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production. (2020) (37)
TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors. (2016) (36)
From embryos to embryoid bodies: generating blood from embryonic stem cells. (2003) (35)
A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. (2018) (35)
Stem cells assessed (2012) (34)
Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells. (2006) (34)
Human iPS cell derivation/reprogramming. (2009) (33)
Enhanced plating efficiency of trypsin-adapted human embryonic stem cells is reversible and independent of trisomy 12/17. (2008) (33)
Interferon-α signaling promotes embryonic HSC maturation. (2016) (32)
A Stem Cell Perspective on Cellular Engineering (2013) (32)
Prospects for stem cell therapeutics: myths and medicines. (2002) (31)
ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokines. (2009) (31)
Disruptive reproductive technologies (2017) (30)
Autologous transplant for CML revisited. (1993) (29)
Application of induced pluripotent stem cells to hematologic disease. (2009) (29)
Missed opportunities in embryonic stem-cell research. (2004) (28)
Towards combination target-directed chemotherapy for chronic myeloid leukemia: role of farnesyl transferase inhibitors. (2003) (27)
Animal models of BCR/ABL-induced leukemias. (1993) (27)
Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges. (2018) (27)
Male germ cells. (2006) (27)
Cellular therapy for fanconi anemia: the past, present, and future. (2011) (26)
In vitro gametogenesis from embryonic stem cells. (2004) (25)
Disease Models from Pluripotent Stem Cells (2009) (25)
Cellular and molecular aspects of amoeboid movement. (1982) (25)
Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing (2019) (24)
Patterning definitive hematopoietic stem cells from embryonic stem cells. (2005) (24)
The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy (2015) (23)
Excision of a viral reprogramming cassette by delivery of synthetic Cre mRNA. (2012) (23)
A screen to identify drug resistant variants to target-directed anti-cancer agents (2003) (23)
Chronic Myeloid Leukemia: (2004) (23)
Transgene expression and RNA interference in embryonic stem cells. (2006) (23)
Lifelong multilineage contribution by embryonic-born blood progenitors (2022) (23)
Telomere dynamics in dyskeratosis congenita: the long and the short of iPS (2011) (22)
Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors (2008) (22)
Differentiation Potential of Histocompatible Parthenogenetic Embryonic Stem Cells (2007) (22)
Cloning and stem cells--handicapping the political and scientific debates. (2003) (22)
Chronic Myeloid Leukemia : Biology and Treatment (2003) (22)
Gleevec Resistance: Lessons for Target-Directed Drug Development (2003) (22)
Towards hematopoietic reconstitution from embryonic stem cells: a sanguine future (2007) (21)
Cellular Alchemy and the Golden Age of Reprogramming (2012) (21)
Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity. (2016) (21)
Towards the generation of patient-specific pluripotent stem cells for combined gene and cell therapy of hematologic disorders. (2007) (21)
Building Capacity for a Global Genome Editing Observatory: Institutional Design. (2018) (21)
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors (2020) (21)
Isolation of hematopoietic stem cells from mouse embryonic stem cells. (2008) (20)
The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia (2019) (20)
Clump passaging and expansion of human embryonic and induced pluripotent stem cells on mouse embryonic fibroblast feeder cells. (2010) (20)
Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting (2020) (20)
AP24163 Inhibits the Gatekeeper Mutant of BCR‐ABL and Suppresses In vitro Resistance (2010) (20)
Chronic myeloid leukemia: proving ground for cancer stem cells. (2004) (19)
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity. (2022) (19)
Phase I Study of Lonafarnib (SCH66336) in Combination with Imatinib for Patients (Pts) with Chronic Myeloid Leukemia (CML) after Failure to Imatinib. (2004) (19)
Anticipating Clinical Resistance to Target-Directed Agents (2006) (19)
Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. (2015) (19)
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis (2010) (19)
microRNAs become macro players in somatic cell reprogramming (2011) (18)
Distinct and Combinatorial Functions of Jmjd 2 b / Kdm 4 b and Jmjd 2 c / Kdm 4 c in Mouse Embryonic Stem Cell Identity (2014) (17)
Live-cell immunofluorescence staining of human pluripotent stem cells. (2011) (17)
Caudal genes in blood development and leukemia (2012) (17)
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity. (2013) (17)
Oral health care in the 21st century: It is time for the integration of dental and medical education. (2020) (17)
Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia (2020) (17)
SARS-CoV-2 epitope-specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability (2022) (16)
rRNA biogenesis regulates mouse 2C-like state by 3D structure reorganization of peri-nucleolar heterochromatin (2021) (16)
Pluripotent stem cells in research and treatment of hemoglobinopathies. (2012) (15)
Stem cells: Reprogramming in situ (2013) (15)
Lin28b regulates age-dependent differences in murine platelet function. (2019) (15)
A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (15)
A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7 (2020) (13)
A novel method to isolate cells with conditional gene expression using fluorescence activated cell sorting. (1997) (13)
Development of hematopoietic repopulating cells from embryonic stem cells. (2003) (13)
LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells (2021) (13)
Mapping the Road to the Clinical Translation of Stem Cells (2008) (13)
LIN 28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans (2015) (11)
Farnesyl transferase inhibitor resistance probed by target mutagenesis. (2007) (11)
Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice (2015) (11)
Isolation of chicken cellular DNA sequences with homology to the region of viral oncogenes that encodes the tyrosine kinase domain (1986) (11)
Human embryonic stem cells flock together (2007) (10)
Genetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation (2004) (10)
PRC 2 Is Required to Maintain Expression of the Maternal Gtl 2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells (2015) (9)
Treatment by design in leukemia, a meeting report, Philadelphia, Pennsylvania, December 2002 (2003) (9)
Derivation of hematopoietic stem cells from murine embryonic stem cells. (2007) (9)
Debugging cellular reprogramming (2007) (9)
Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment (2019) (9)
Stem cells: Triple genomes go far (2011) (9)
Alternative Splicing of MBD 2 Supports Self-Renewal in Human Pluripotent Stem Cells (2014) (9)
Chronic Myeloid Leukemia — A Brief History (2007) (9)
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells (2011) (8)
Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System (2020) (8)
Alchemy in the liver: fact or fusion? (2004) (8)
Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo (2018) (8)
Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2 (2021) (7)
Resistance to the Farnesyl Transferase Inhibitor SCH66336/Lonafarnib Caused by Mutations in the Target Protein Farnesyl Transferase Beta. (2004) (7)
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis (2022) (7)
Defining cellular identity through network biology (2014) (7)
Dodging the Magic Bullet: Understanding Imatinib Resistance (2003) (7)
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development (2022) (6)
COVID Highlights Another Crisis: Lack of Black Physicians and Scientists (2020) (6)
Evidence generation and reproducibility in cell and gene therapy research: A call to action (2021) (6)
A new route to human embryonic stem cells (2013) (6)
Deriving blood stem cells from pluripotent stem cells for research and therapy. (2014) (6)
Another horse in the meta-stable state of pluripotency. (2010) (6)
AID for reprogramming (2010) (6)
Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells” (2013) (6)
An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation. (2020) (6)
Customized human embryonic stem cells (2005) (5)
Derivation of human embryonic stem cells with NEMO deficiency. (2012) (5)
Hematopoietic defects and iPSC disease modeling: lessons learned. (2013) (5)
Two new routes to make blood: Hematopoietic specification from pluripotent cell lines versus reprogramming of somatic cells. (2015) (5)
Histocompatible embryonic stem cells (2008) (5)
Stem cell research: science, ethics and policy. (2005) (5)
Efficient gene knockdowns in human embryonic stem cells using lentiviral-based RNAi. (2009) (5)
STEM CELLS ® EMBRYONIC STEM CELLS / INDUCED PLURIPOTENT STEM CELLS Induced Pluripotent Stem Cells with a Pathological Mitochondrial DNA Deletion (2013) (5)
The Repatterning of Eukaryotic Genomes by Random Genetic Drift (2012) (4)
Stem cells: Valine starvation leads to a hungry niche (2016) (4)
Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient‐Derived Induced Pluripotent Stem Cells (2012) (4)
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR-mutant lung cancer (2021) (4)
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy. (2021) (4)
Erratum: Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (2012) (4)
Correction: Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice (2015) (4)
Autophagy: It's in Your Blood. (2017) (3)
Derivation of Hematopoietic Stem Cells from Embryonic Stem Cells. (2004) (3)
Derivation of Hematopoietic Stem Cells from Embryonic Stem Cells. (2004) (3)
From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond. (2010) (3)
Inhibition of Retinoic Acid Signaling by the cdx-hox Pathway Is Essential for Blood Cell Formation during Embryogenesis. (2004) (3)
A chemical logic for reprogramming to pluripotency (2013) (3)
Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing (2018) (3)
Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells (2022) (3)
Dissection of Bcr-abl Structural Domains Relating to Kinase Auto-Inhibition Using a Forward Mutational Screen with the Non-ATP Competitive Inhibitor GNF-2. (2007) (3)
Patient-Specific Induced Pluripotent Stem Cells in Hurler Syndrome (2008) (3)
Rationalizing autotransplant strategies for chronic myeloid leukemia. (1996) (3)
Lin28 paralogs regulate lung branching morphogenesis (2021) (3)
Modeling Bone Marrow Failure and MDS in Shwachman Diamond Syndrome Using Induced Pluripotent Stem Cells (2016) (2)
Telomere Elongation in Dyskeratosis Congenita Induced Pluripotent Stem Cells. (2009) (2)
The nomenclature system should be sustainable, but also practical. (2011) (2)
requires the CCL 6 and CCL 9 chemokines induced leukemia − ICSBP-mediated immune protection against BCR (2009) (2)
Signaling through RNA-binding proteins as a cell fate regulatory mechanism (2017) (2)
Is There Merit in Merit Aid? (2017) (2)
Patient-Specific Pluripotent Stem Cells for Hematologic Disease. (2009) (2)
Prostaglandin E2 Is a Potent Regulator of Vertebrate Hematopoietic Stem Cell Homeostasis. (2006) (2)
A Systems Biology Approach to Study the Acquisition of Adult Repopulating Potential During Hematopoietic Stem Cell Ontogeny. (2009) (2)
Lin28B/Let-7 Axis Regulates Multiple Myeloma Proliferation By Enhancing c-Myc and Ras Survival Pathways (2013) (2)
Single-cell analysis uncovers mechanisms of plasticity in leukemia initiating cells (2020) (2)
Enucleation and Beta-Globin Expression in Induced Red Blood Cells: A Platform to Model Sickle Cell Anemia (2017) (2)
Current prospects for the generation of patient-specific pluripotent cells from adult tissues. (2007) (2)
Reassembling embryos in vitro from component stem cells (2017) (2)
Generation of Retinal Precursors From Murine ips Cells (2009) (2)
Interferons and IRF8/ICSBP Stimulate Immune Protection Against BCR/ABL-Induced Leukemia. (2004) (2)
HEMATOPOIESIS AND STEM CELLS Notch 1 acts via Foxc 2 to promote de fi nitive hematopoiesis via effects on hemogenic endothelium (2015) (1)
LIN 28 Regulates Stem Cel l Metabolism and Conversion to Primed Pluripotency Graphical (1)
Msi2 Maintains Normal Hematopoietic Stem Cell Self-Renewal (2011) (1)
Ezh1 Inhibits Commitment to Hemogenic Fate and HSPC Formation during Vertebrate Development (2019) (1)
Abstract 1732: Switch to MET oncogene dependence as a novel mechanism of drug resistance inEGFR-mutant lung cancer (2019) (1)
Reconstruction of complex single-cell trajectories using CellRouter (2018) (1)
and murine embryonic stem cells Surface antigen phenotypes of hematopoietic stem cells from embryos (2014) (1)
Targeted inhibition of Gatekeeper variant “T315I” of BCR-ABL by a purine based ATP-competitive inhibitor (2006) (1)
Novel Epigenetic Vulnerabilities for Diffuse Large B-Cell Lymphoma (2018) (1)
A Unified Mechanism of Tyrosine Kinase Regulation by the Gatekeeper Residue. (2007) (1)
Large Intergenic Non‐Coding RNAs in Chromatin, Cancer and Stem Cells (2011) (1)
Hemogenic Endothelial Progenitors Cells Isolated from Human Umbilical Cord Blood (2010) (1)
Short hairpin RNAs artifactually impair cell growth and suppress clustered microRNA expression (2018) (1)
Author Correction: Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis (2019) (1)
Introduction to the Special Issue on CRISPR (2020) (1)
Hematopoietic stem/progenitor cell conversion from human pluripotent stem cells (2017) (1)
Dissecting reprogramming, differentiation and conversion with network biology. (2014) (1)
The Rho GTPase Rac1 Is Not Required for Definitive Hematopoietic Specification in ES-Derived Hematopoiesis. (2009) (1)
Mechanisms of Leukemia Stem Cell Plasticity Revealed By Single Cell Analysis (2020) (1)
Histone Methylation-Adenosylmethionine and S Influence of Threonine Metabolism on (1)
BCR-ABL Kinase Dynamics and Drug Resistance. (2005) (1)
Reprogramming: What's Unknown? (2011) (1)
Hematopoiesis at single cell resolution spanning human development and maturation (2021) (1)
Functional evaluation of ES-somatic cell hybrids in vitro and in vivo. (2014) (1)
Generation of Induced Pluripotent Stem Cells From Peripheral Blood of Coronary Artery Disease Patients (2009) (1)
Haematopoietic progenitor and lymphoid differentiation from human pluripotent stem cells (2018) (1)
Mesodermal Patterning Activity of the Transcription Factor SCL. (2007) (1)
Telomereelongationininducedpluripotentstemcells from dyskeratosis congenita patients (2010) (1)
HEMATOPOIESIS AND STEM CELLS Notch-HES 1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells (2013) (1)
c-Src kinase domain Thr338Ile mutant in complex with ATPgS (2008) (1)
Drug discovery using induced pluripotent stem cells identifies autophagy as a therapeutic pathway for anemia (2016) (1)
Cdx 4 Is Dispensable for Murine Adult Hematopoietic Stem Cells but Promotes MLL-AF 9-Mediated Leukemogenesis (2010) (1)
NF-κB activation impairs somatic cell reprogramming in ageing (2015) (1)
Monitoring Imatinib Resistance with a “Polony” Assay: Towards Tailored Therapy of Chronic Myelogenous Leukemia (CML). (2006) (1)
Introducing a “How‐to” Guide to Embryonic Stem Cell Manipulation (2004) (1)
Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo (2011) (1)
Genetic events in CML: from translocation to transplantation. (1994) (1)
INFLAMMASOME-MEDIATED EXPANSION OF THE HEMATOPOIETIC SYSTEM IN THE VERTEBRATE EMBRYO (2019) (1)
Lin28b-Let-7-PRC1 Axis Guides Developmental Maturation of the Hematopoietic System (2021) (1)
Hematopoietic Stem Cells (2009) (1)
Corrigendum: Failure to replicate the STAP cell phenomenon (2015) (1)
Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (1)
New Initiatives for the ISSCR (2007) (1)
INVESTIGATING THE ROLE OF EZH1 IN DEVELOPMENTAL HEMATOPOIESIS (2019) (1)
Proteolytic autodigestion (2013) (1)
Region of Viral Oncogenes That Encodes the Tyrosine (2003) (0)
Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells (2015) (0)
Abstract 5438: Directed Differentiation of Endothelial Cells From Coronary Artery Disease (CAD) Patients-derived iPS Cells (2009) (0)
Introduction to the Special Issue on CRISPR (2020) (0)
A Critical Role for CCL Chemokines in the Immuno-Protection Induced by Type I Interferons and IRF8/ICSBP Against Bcr/Abl-Induced Leukemia. (2007) (0)
Modeling Bone Marrow Failure Syndromes with Induced Pluripotent Stem Cells (2010) (0)
Abstract LB-165: Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma (2016) (0)
Epoxyeicosatrienoic Acids Regulate Hematopoietic Stem/Progenitor Cell Fate Decision During Stress Response and Embryonic Hematopoiesis (2011) (0)
Modeling germ cell differentiation (2008) (0)
Generation and patterning of patient-specific pluripotent stem cells (2008) (0)
Piezo1-Sensitive Biomechanical Pulsation Stimulates Long-Term Hematopoietic Stem Cell Formation (2018) (0)
transgenic mice with the farnesyl transferase inhibitor SCH66336 Treatment of Bcr/Abl-positive acute lymphoblastic leukemia in P190 (2013) (0)
3090 – KDM4A/C SUSTAIN AN ONCOGENIC PROGRAM BY EPIGENETIC REWIRING OF ONCOGENIC AND LINEAGE ENHANCERS (2020) (0)
Global Forum Discusses Stem Cell Research Strategy (2008) (0)
Abstract SY04-03: Molecular networks defining cell identity (2015) (0)
SCH66336 Overcoming STI571 resistance with the farnesyl transferase inhibitor (2013) (0)
3100 – A SINGLE CELL ATLAS OF MOUSE HEMATOPOIETIC ORGANS (2020) (0)
Today@Biozentrum/Pharmazentrum Seminar Series (2015) (0)
Engineering antigen-specific T cells from human pluripotent stem cells (2018) (0)
Modeling Diamond Blackfan Anemia in Vivo Using Human Induced Pluripotent Stem Cells (2014) (0)
Milestones and barriers in hematopoietic stem cell derivation from pluripotent stem cells (2014) (0)
Cellular transformation and leukemia development by activated tyrosine kinases (2008) (0)
BMP4 Favors Hematopoietic Differentiation from Murine Embryonic Stem Cells and Acts by Activation of the cdx-hox Pathway. (2005) (0)
BMP and WNT-Directed Transcription Factors TCF7L2/TCF4 and SMAD1 Bind to Distinct Hematopoietic-Specific Target Genes Depending on Cell Lineage (2010) (0)
Abstract 1040: LIN28B-mediatedlet-7independent activation of AKT promotes neuroblastoma pathogenesis (2017) (0)
Interspecies Nuclear Transfer of Human Adult Dermal Fibroblast Cells. (2008) (0)
Cytokines: Hematopoietic Growth Factors (2002) (0)
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target (2020) (0)
Examining the Role of EZH1 in the Regulation of Definitive Hematopoiesis (2018) (0)
Abstract 2948: The role of the RNA binding protein LIN28B in neuroblastoma (2012) (0)
The zebrafish homologue of the murine Evi-1 gene regulates zebrafish embryonic blood development (2010) (0)
Single Cell Resolution Mapping of Hematopoietic Stem and Progenitor Cell States throughout Human Life (2020) (0)
Against hyperbole, distortion, and overselling (2016) (0)
Abstract LB-290: Multiple distinct mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma (2015) (0)
Fox for treating disease Use of differentiated pluripotent stem cells as replacement therapy (2014) (0)
Abstract B165: Abl kinase myristate‐site inhibitor, mechanism and application (2009) (0)
Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (0)
3126 – SINGLE CELL SEQUENCING OF MLL-REARRANGED LEUKEMIA REVEALS MECHANISMS OF LEUKEMIA INITIATING CELL PLASTICITY (2020) (0)
ES cells prove egg-straordinary (2003) (0)
HEMATOPOIESIS AND STEM CELLS TGF- b inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors (2016) (0)
requires the CCL6 and CCL9 chemokines induced leukemia - ICSBP-mediated immune protection against BCR-ABL (2014) (0)
3127 – MODELING PREDISPOSED AND SPORADIC CLONAL HEMATOPOIESIS USING INDUCED PLURIPOTENT STEM CELLS (2020) (0)
Inhibition of BCR/ABL-T315I by Dismantling the Hydrophobic Spine. (2008) (0)
Engineering of Induced Pluripotent Stem Cell-Derived Hemogenic Endothelium (2017) (0)
Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions (2012) (0)
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development (2022) (0)
Induced pluripotent stem cells in disease modelling and drug discovery (2019) (0)
Author Correction: Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis (2020) (0)
Optimized Beta-Globin Expression and Enucleation from Induced Red Blood Cells for In Vitro Modeling of Sickle Cell Disease (2018) (0)
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-PRC1 axis (2022) (0)
Induction biomécanique de l'hématopoïèse (2010) (0)
An Essential Role for the RNA Editor-Exonuclease Axis in Terminal Erythroid Differentiation (2020) (0)
A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (0)
BMP and Wnt Induce Embryonic Blood Fate by Activation of the Cdx-Hox Pathway. (2007) (0)
Direct RNA Target Analysis Identifies Signatures That Define Msi2's Role in Sustaining HSC Cell Fate. (2012) (0)
Lymphoid-myeloro repopulating potential of embryonic stem cell derivatives expressing bcr/abl (2000) (0)
Chapter 48 – Hematopoietic Stem Cells (2013) (0)
Scientiﬁc and clinical opportunities for modeling blood disorders with embryonic stem cells (2006) (0)
25 – Hematopoietic Stem Cells (2004) (0)
Engineering hematopoietic stem and progenitor cells from human pluripotent stem cells for modeling congenital anemias (2014) (0)
Modeling Fanconi Anemia Using Human Induced Pluripotent Stem Cells By Reversible Complementation (2018) (0)
BMP Signaling Via the Cdx-Hox Pathway Allocates Mesoderm to Hematopoietic vs Cardiac Fates. (2006) (0)
The Zebrafish Homologue of the Murine Ecotropic Viral Integration Site-1 (. Evi-1) gene Regulates Zebrafish Embryonic Blood Development. (2009) (0)
Developmental Cell Nanog-like-Mxtx 2-Nodal Pathway in Endoderm Forming (2012) (0)
231 HISTOCOMPATIBLE PARTHENOGENETIC EMBRYONIC STEM CELLS (2007) (0)
Extracellular vesicles improve GABAergic transmission in Huntington’s disease iPSC-derived neurons (2022) (0)
Erratum to: Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity (2010) (0)
Procede d'augmentation de la proliferation et/ou de la differentiation hematopoietique de cellules souches (2003) (0)
Making HSCs on Demand: Looking Ahead. (2017) (0)
A high-throughput chemical genetic screen in zebrafish establishes that prostaglandin E2 is a potent regulator of hematopoietic stem cell formation (2007) (0)
Vitamin D regulates hematopoietic stem cell maintenance by two distinct mechanisms (2014) (0)
Blastcrisis inamurinemodelofchronic myelogenous leukemia (1991) (0)
Derivation of Disease-Free Induced Pluripotent Stem Cells From Patients with Pearson Marrow Pancreas Syndrome (2010) (0)
Ectopic Expression of Lin28 Biases Myeloid Differentiation to Promote an Immature Mast Cell State and Is Implicated in Aggressive Mastocytosis (2014) (0)
Abstract IA17: The stem cell factor LIN28 in pediatric cancer (2013) (0)
Abstract 5436: Generation of Induced Pluripotent Stem Cells From Peripheral Blood of Coronary Artery Disease Patients (2009) (0)
The Year Ahead (2007) (0)
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME LXXIII (2009) (0)
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells Via Transcription Factor Conversion of Hemogenic Endothelium (2016) (0)
Anniversary reflections: ISSCR presidents on 20 years of progress. (2022) (0)
Dipping a toe in the fountain of youth (2022) (0)
Part D: Directed Differentiation of Human Embryonic Stem Cells into Hematopoeitic in vivo Repopulating Cells (2007) (0)
STRUCTURAL CONFORMATION OF TYPE I COLLAGEN MATRICES MODULATES RETINOIC-ACID INDUCED SMOOTH MUSCLE CELL DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS (2008) (0)
Scl and Notch Act Downstream of Hedgehog Signaling to Promote Embryonic Hematopoiesis From Endothelial Cells (2011) (0)
Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway (2010) (0)
Chemokine Receptor 1 and its associated immune pathway are downregulated in SF3B1MT blood and non-blood cancers (2022) (0)
A Dual Role of Evi-1 During Developmental Hematopoiesis (2012) (0)
Human endogenous retrovirus K (HML-2) RNA and protein expression is a marker for human embryonic and induced pluripotent stem cells (2013) (0)
Explorer Generation of Functional Human Hepatic Endoderm from Human Induced Pluripotent Stem Cells (2017) (0)
Abstract 2975: The pluripotency factor LIN28 promotes colorectal tumorigenesis and tumor progression (2014) (0)
Ovarian Cancer and Reproductive System Biology: A Harvard Stem Cell Institution Consortium (2010) (0)
Today@Biozentrum/Pharmazentrum Seminarreihen (2015) (0)
Reduced Marcks-related protein expression promotes in vitro cell invasion and tumor desmoplasia (2008) (0)
3007 – POLYVINYL ALCOHOL AND THE EMERGING TRANSLATABILITY OF IPSC-DERIVED RED BLOOD CELLS FOR DISEASE MODELING AND CLINICAL USE (2020) (0)
Stromal-Derived Factor-1? The BCR/ABL Oncogene Alters the Chemotactic Response to (2012) (0)
Raman microspectroscopy reveals unsaturation heterogeneity at the lipid droplet level and validates an in vitro model of bone marrow adipocyte subtypes (2022) (0)
Isolation ofChicken Cellular DNA Sequences withHomology tothe Region ofViral Oncogenes ThatEncodes theTyrosine (1986) (0)
Immune-Mediated Protection Against BCR/ABL-Induced Leukemia: A Common Pathway Shared between IRF8/ICSBP and IFN alpha and beta. (2005) (0)
Neonatal Recipients Offer Permissive Hematopoietic Microenvironment for Engraftment of Embryonic Murine Hematopoietic Stem Cells (2011) (0)
Cdx4 Is Dispensable for Murine Hematopoiesis and MLL-AF9 Mediated Leukemogenesis. (2008) (0)
Simplifying hESC culture (2005) (0)
chicken c-Src kinase domain in complex with ATPgS (2008) (0)
Issue Information-Mission & Focus. (2016) (0)
923. Modeling hematopoietic transplantation with ES cells (2004) (0)
ENHANCED ORGANOGENESIS THROUGH MANIPULATION OF LIN28/LET-7/DIS3L2 (2018) (0)
Chapter 16 – Hematopoietic Stem Cells (2014) (0)
Bone Marrow Adipocytes Prevent Hematopoietic Expansion in Homeostasis and in Bone Marrow Transplantation (2008) (0)
Msi2 Directly Regulates The TGF-β Signaling Pathway and Myeloid Lineage Bias In Hematopoietic Stem Cells (2013) (0)
Evi-1 Regulates Myelopoiesis and Hematopoietic Stem Cell Development in Zebrafish and Human Pluripotent Stem Cells (2011) (0)
Understanding and Harnessing the Immune System for the Rational Design of Therapies and Vaccines (2013) (0)
Single Cell Analysis Elucidates the Maturation of Human Stem and Progenitor Cell Function from Fetal through Adult Hematopoiesis (2021) (0)
Konrad Hochedlinger: ISSCR Outstanding Young Investigator for 2009 (2009) (0)
Blood Notch-Foxc2 2015 All with Suppl (2015) (0)
Hematopoietic Development From Human Induced Pluripotent Stem Cells. (2009) (0)
Bone Marrow Adipocytes: A Novel Negative Regulator of the Hematopoietic Microenvironment. (2007) (0)
HEMATOPOIESIS AND STEM CELLS Interferon- a signaling promotes embryonic HSC maturation (2016) (0)
chronic myeloid leukemia BCR/ABL-induced murine leukemia and primary cells from patients with Activity of the farnesyl protein transferase inhibitor SCH66336 against (2013) (0)
Resource Disease-Specific Induced Pluripotent Stem Cells (0)
PRC 2 Is Required to Maint ain Expression of the Maternal Gtl 2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells Graphical (2015) (0)
Modeling Cystic Fibrosis (CF) with Induced Pluripotent Stem Cells (2020) (0)
Transgenes Targeted to the HPRT Locus and Expressed from a Tetracycline-Inducible Promoter Are Silenced during Embryonic Stem Cell Differentiation. (2005) (0)
Interferon-gamma pathway regulates emergence of engraftable hematopoietic stem and progenitor cells from human pluripotent stem cells (2017) (0)
Urological Survey Uro-Science Re : miR-28-5 p Promotes Chromosomal Instability in VHL-Associated Cancers by Inhibiting Mad 2 Translation (2015) (0)
Imatinib-Resistant BCR-ABL Mutant Cellular Screening Paradigm To Characterize Promising Small-Molecule Inhibitors: T315I-BCR-ABL Targeted Drug Discovery. (2006) (0)
Human embryonic stem cell protocols (2006) (0)
UROEPITHELIAL DIFFERENTIATION OF MOUSE EMBRYONIC STEM CELLS USING NOVEL TISSUE CULTURE SYSTEMS (2009) (0)
Abstract 2300: LIN28 cooperates with Wnt signaling to drive invasive intestinal and colorectal adenocarcinoma in mouse and human (2015) (0)
Corrigendum: Hallmarks of pluripotency (2015) (0)
Inhibition of Let-7 Maturation By Lin28b Controls Timing of Embryonic and Adult Myeloid Progenitor Phenotypes during Development (2014) (0)
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells (2011) (0)
Modulators of HSC Engraftment Found in A Competitive Marrow Transplantation Screen in Adult Zebrafish. (2009) (0)
3177 – THE LARGE-SCALE GENERATION OF MATURE, HEMOGLOBINIZED RED BLOOD CELLS IN VITRO FROM HUMAN PLURIPOTENT STEM CELLS FOR DISEASE MODELING AND AUTOLOGOUS THERAPIES (2019) (0)
MYC Regulation Via the LIN28B/Let-7 Axis in Multiple Myeloma (2015) (0)
The ISSCR in China (2008) (0)
Retinoic Acid Blockade Increases Primitive Blood Cell Formation in cdx4 Mutant Zebrafish Embryos, Murine Yolk Sac Explants and Differentiated Embryonic Stem Cells. (2007) (0)
Stem cell myeloproliferative disease and T-lymphoma induced in mice by the ZNF198-FGFR1 fusion gene of human 8p11 myeloproliferative syndrome (2002) (0)
2001 – PLASTICITY OF B-LYMPHOBLASTIC LEUKEMIA STEM CELLS (2021) (0)
[Illinois] ECE 416 Guest Speaker Dr. Greg Underhill (2013) (0)
[Illinois] ECE 416 Guest Speaker Dr. Sua Myong (2013) (0)
3017 – MECHANISMS OF FLOW-DRIVEN TRANSCRIPTIONAL CONTROL OF HEMATOPOIETIC STEM CELL DEVELOPMENT VIA YAP/TAZ REGULATION (2022) (0)
2005 – EZH1/2 REGULATES THE TRANSITION FROM ARTERIAL TO HEMOGENIC FATE IN THE VERTEBRATE EMBRYO (2021) (0)
Balancing work and life: a conversation with George Daley. Interviewed by Majlinda Lako and Susan Daher. (2009) (0)
Association of Lin28 Expression and Tumorigenesis in Human Wilms’ Tumor Cell Lines (2013) (0)
3020 – CELLCOMM REVEALS CELLULAR CROSSTALK THAT DRIVES HEMATOPOIETIC STEM CELL DEVELOPMENT (2021) (0)
3097 – RNA EDITOR-EXONUCLEASE AXIS SCULPTS THE TRANSCRIPTOME DURING TERMINAL ERYTHROID DIFFERENTIATION (2022) (0)
2017 – HUMAN HEMATOPOIETIC STEM CELL ONTOGENY ACROSS DEVELOPMENT AND MATURATION (2022) (0)

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