George R. Dubyak
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Engineering Computer Science
George R. Dubyak's Degrees
- PhD Computer Science Stanford University
- Masters Electrical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)George R. Dubyak's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. (1993) (1237)
- Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages1 (2007) (558)
- Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells. (1989) (553)
- Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. (2008) (552)
- Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. (2004) (363)
- Towards a revised nomenclature for P1 and P2 receptors. (1997) (361)
- Differential Requirement of P2X7 Receptor and Intracellular K+ for Caspase-1 Activation Induced by Intracellular and Extracellular Bacteria* (2007) (354)
- Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation (2011) (352)
- The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor. (1980) (296)
- Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP (2016) (284)
- Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis (2018) (270)
- Intracellular calcium changes trigger connexin 32 hemichannel opening (2006) (263)
- Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. (1999) (234)
- Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. (2000) (232)
- Isoquinolines as antagonists of the P2X7 nucleotide receptor: high selectivity for the human versus rat receptor homologues. (1998) (227)
- Potentiation of Caspase-1 Activation by the P2X7 Receptor Is Dependent on TLR Signals and Requires NF-κB-Driven Protein Synthesis1 (2005) (212)
- Colocalization of ATP Release Sites and Ecto-ATPase Activity at the Extracellular Surface of Human Astrocytes* (2003) (207)
- K+ Efflux Agonists Induce NLRP3 Inflammasome Activation Independently of Ca2+ Signaling (2015) (207)
- Signal transduction by P2-purinergic receptors for extracellular ATP. (1991) (206)
- Induction of the P2z/P2X7 nucleotide receptor and associated phospholipase D activity by lipopolysaccharide and IFN-gamma in the human THP-1 monocytic cell line. (1996) (202)
- Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux (2015) (191)
- Cutting Edge: The Nucleotide Receptor P2X7 Contains Multiple Protein- and Lipid-Interaction Motifs Including a Potential Binding Site for Bacterial Lipopolysaccharide1 (2001) (187)
- Differential activation of cation channels and non-selective pores by macrophage P2z purinergic receptors expressed in Xenopus oocytes. (1994) (185)
- Marek's Disease Virus (MDV) Encodes an Interleukin-8 Homolog (vIL-8): Characterization of the vIL-8 Protein and a vIL-8 Deletion Mutant MDV (2001) (179)
- P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1β Release1 (2003) (176)
- P2X7 receptor regulation of non‐classical secretion from immune effector cells (2012) (171)
- N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis (2020) (170)
- Modulation of P2X7 nucleotide receptor expression by pro‐ and anti‐inflammatory stimuli in THP‐1 monocytes (1998) (163)
- Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling* (2015) (157)
- Cutting Edge: Human β Defensin 3—A Novel Antagonist of the HIV-1 Coreceptor CXCR41 (2006) (156)
- P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1 1 (2009) (156)
- Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis. (2012) (153)
- Antipyrylazo III, a "middle range" Ca2+ metallochromic indicator. (1978) (148)
- A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages. (1992) (145)
- Essential role for Ca2+ in regulation of IL-1beta secretion by P2X7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells. (2003) (139)
- Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms. (1988) (138)
- Insulin-mimetic effects of vanadate in isolated rat adipocytes (1980) (138)
- Calcium Is a Key Signaling Molecule in β-Lapachone-mediated Cell Death* (2001) (137)
- Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor‐independent mechanisms (2003) (131)
- Maitotoxin and P2Z/P2X7purinergic receptor stimulation activate a common cytolytic pore. (1999) (129)
- Regulation of P2X(7) nucleotide receptor function in human monocytes by extracellular ions and receptor density. (2001) (128)
- Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides (2016) (127)
- Extracellular pyrophosphate metabolism and calcification in vascular smooth muscle. (2011) (120)
- Cutting edge: human beta defensin 3--a novel antagonist of the HIV-1 coreceptor CXCR4. (2006) (119)
- Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1β via Caspase-8 in Dendritic Cells (2013) (118)
- P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways (2009) (115)
- Inhibitory Effects of Chloride on the Activation of Caspase-1, IL-1β Secretion, and Cytolysis by the P2X7 Receptor1 (2005) (114)
- T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis (2016) (114)
- Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells. (1985) (113)
- Extracellular adenosine triphosphate activates calcium mobilization in human phagocytic leukocytes and neutrophil/monocyte progenitor cells. (1989) (111)
- Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells. (1986) (109)
- Ion homeostasis, channels, and transporters: an update on cellular mechanisms. (2004) (107)
- Mycobacterium tuberculosis Synergizes with ATP To Induce Release of Microvesicles and Exosomes Containing Major Histocompatibility Complex Class II Molecules Capable of Antigen Presentation (2010) (106)
- Mitogenic signals for platelet-derived growth factor isoforms in liver fat-storing cells. (1991) (99)
- Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor (2018) (98)
- IKKα negatively regulates ASC-dependent inflammasome activation (2014) (91)
- Go It Alone No More—P2X7 Joins the Society of Heteromeric ATP-Gated Receptor Channels (2007) (90)
- Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'-nucleotidase in myeloid leukocytes. (1997) (87)
- Factor XII and uPAR upregulate neutrophil functions to influence wound healing (2018) (85)
- Mutation of a Dibasic Amino Acid Motif Within the C Terminus of the P2X7 Nucleotide Receptor Results in Trafficking Defects and Impaired Function 1 (2003) (85)
- The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes. (1998) (84)
- CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy (2016) (84)
- Different calcium dependence of the capping and cutting activities of villin. (1986) (84)
- NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx. (2016) (83)
- Calcium is a key signaling molecule in beta-lapachone-mediated cell death. (2001) (80)
- Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. (2001) (76)
- Detection of local ATP release from activated platelets using cell surface-attached firefly luciferase. (1999) (76)
- Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis. (2020) (75)
- Stealth filaments: Polymer chain length and conformation affect the in vivo fate of PEGylated potato virus X. (2015) (74)
- Maitotoxin and P2Z/P2X(7) purinergic receptor stimulation activate a common cytolytic pore. (1999) (73)
- Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells. (1988) (73)
- Chemotherapeutic Drugs Induce ATP Release via Caspase-gated Pannexin-1 Channels and a Caspase/Pannexin-1-independent Mechanism* (2014) (73)
- Both sides now: multiple interactions of ATP with pannexin-1 hemichannels. Focus on "A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP". (2009) (70)
- Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: synergistic modulation by cyclic AMP and hyperphosphatemia. (2010) (70)
- Dissociation of the pore-forming and phospholipase D activities stimulated via P2z purinergic receptors in BAC1.2F5 macrophages. Product inhibition of phospholipase D enzyme activity. (1993) (67)
- Phospholipase C activation by prostaglandins and thromboxane A2 in cultured mesangial cells. (1988) (67)
- Phospholipase D activity in phagocytic leucocytes is synergistically regulated by G-protein- and tyrosine kinase-based mechanisms. (1993) (66)
- Decreased Protein Kinase C Activity During Cerebral Ischemia and After Reperfusion in the Adult Rat (1990) (66)
- Down-regulation of P2U-purinergic nucleotide receptor messenger RNA expression during in vitro differentiation of human myeloid leukocytes by phorbol esters or inflammatory activators. (1997) (66)
- Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation (2004) (65)
- Differing caspase‐1 activation states in monocyte versus macrophage models of IL‐1β processing and release (2004) (65)
- Regulation of phospholipase D and primary granule secretion by P2-purinergic- and chemotactic peptide-receptor agonists is induced during granulocytic differentiation of HL-60 cells. (1991) (63)
- Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages. (2004) (62)
- Differential Regulation of P2X7 Receptor Activation by Extracellular Nicotinamide Adenine Dinucleotide and Ecto-ADP-Ribosyltransferases in Murine Macrophages and T Cells (2009) (61)
- Chronic Treatment With P2‐Purinergic Receptor Agonists Induces Phenotypic Modulation of the HL‐60 and U937 Human Myelogenous Leukemia Cell Lines (1991) (60)
- TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation (2018) (60)
- Enhanced activation of Akt and extracellular‐regulated kinase pathways by simultaneous occupancy of Gq‐coupled 5‐HT2A receptors and Gs‐coupled 5‐HT7A receptors in PC12 cells (2005) (59)
- Knock-out mice reveal tissue-specific roles of P2Y receptor subtypes in different epithelia. (2003) (59)
- Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells. (2009) (59)
- Endotoxin Activation of Macrophages Does Not Induce ATP Release and Autocrine Stimulation of P2 Nucleotide Receptors1 (2000) (59)
- Relationship between phospholipase C activation and prostaglandin E2 and cyclic adenosine monophosphate production in rabbit tubular epithelial cells. Effects of angiotensin, bradykinin, and arginine vasopressin. (1988) (59)
- Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. (2008) (58)
- Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition. (2017) (57)
- Erratum: Maitotoxin induces biphasic interleukin-1β secretion and membrane blebbing in murine macrophages (Molecular Pharmacology (2004) 66 (909-920)) (2004) (54)
- Expression of the pore-forming P2Z purinoreceptor in Xenopus oocytes injected with poly(A)+ RNA from murine macrophages. (1993) (53)
- Purinergic signaling at immunological synapses. (2000) (51)
- Biological Actions of Extracellular ATP. (1991) (50)
- Calcium currents in the A7r5 smooth muscle-derived cell line (1990) (50)
- Live-cell visualization of gasdermin D-driven pyroptotic cell death (2017) (49)
- Agonist-induced calcium transients in cultured smooth muscle cells: measurements with fura-2 loaded monolayers. (1986) (48)
- Guanine-nucleotide- and adenine-nucleotide-dependent regulation of phospholipase D in electropermeabilized HL-60 granulocytes. (1991) (47)
- Effects of 12-O-tetradecanoyl-phorbol-13-acetate on Myofibril integrity and Ca2+ content in developing myotubes. (1982) (47)
- Human epidermal keratinocytes undergo (-)-epigallocatechin-3-gallate-dependent differentiation but not apoptosis. (2005) (47)
- Role of Calcium in Glucocorticosteroid-Induced Apoptosis of Thymocytes and Lymphoma Cells: Resurrection of Old Theories by New Findings (1998) (44)
- Na+/H+ exchange in Ehrlich ascites tumor cells. Regulation by extracellular ATP and 12-O-tetradecanoylphorbol 13-acetate. (1986) (44)
- Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1. (2011) (44)
- ATP-induced potentiation of G-protein-dependent phospholipase D activity in a cell-free system from U937 promonocytic leukocytes. (1993) (43)
- Stimulation of cytosolic free calcium and inositol phosphates by prostaglandins in cultured rat mesangial cells. (1987) (43)
- The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes (2013) (42)
- Essential role for Ca 2 (cid:1) in regulation of IL-1 (cid:2) secretion by P2X 7 nucleotide receptor in monocytes, macrophages, and HEK-293 cells (2003) (40)
- Effects of PDGF on inositol phosphates, Ca2+, and contraction of mesangial cells. (1987) (39)
- Functional expression of the parathyroid cell calcium receptor in Xenopus oocytes (1993) (39)
- Angiotensin II activates the beta 1 isoform of phospholipase C in vascular smooth muscle cells. (1997) (39)
- Resistance to etoposide in human leukemia HL-60 cells: reduction in drug-induced DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides. (1996) (38)
- Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells. (2010) (38)
- Identification and transmembrane signaling of leukotriene D4 receptors in human mesangial cells. (1988) (36)
- Regulation of cytosolic pH of cultured mesangial cells by prostaglandin F2 alpha and thromboxane A2. (1991) (36)
- Pertussis toxin produces differential inhibitory effects on basal, P2-purinergic, and chemotactic peptide-stimulated inositol phospholipid breakdown in HL-60 cells and HL-60 cell membranes. (1990) (35)
- Activation of calcium mobilization and calcium influx by alpha 1-adrenergic receptors in a smooth muscle cell line. (1985) (34)
- P2-purinergic receptors activate a guanine nucleotide-dependent phospholipase C in membranes from HL-60 cells. (1990) (34)
- Endothelin‐1 Activates the Phosphoinositide Cascade in Cultured Glomerular Mesangial Cells (1989) (33)
- Interactions between IFs, Microtubules, and Myofibrils in Fibrogenic and Myogenic Cells a (1985) (32)
- ATP and Control of Intracellular Growth of Mycobacteria by T Cells (2002) (32)
- Expression of multiple ATP receptor subtypes during the differentiation and inflammatory activation of myeloid leukocytes (1996) (31)
- Sulfated Signal from ASJ Sensory Neurons Modulates Stomatin-dependent Coordination in Caenorhabditis elegans* (2006) (31)
- Lipopolysaccharide, IFN-γ, and IFN-β Induce Expression of the Thiol-Sensitive ART2.1 Ecto-ADP-Ribosyltransferase in Murine Macrophages1 (2007) (31)
- Modification of β-Defensin-2 by Dicarbonyls Methylglyoxal and Glyoxal Inhibits Antibacterial and Chemotactic Function In Vitro (2015) (28)
- Reciprocal Changes in Phosphoenolpyruvate Carboxykinase and Pyruvate Kinase with Age Are a Determinant of Aging in Caenorhabditis elegans* (2015) (26)
- Effect of atrial natriuretic factor on cytosolic free calcium in rat glomerular mesangial cells (1987) (26)
- Immune complex activation of rat glomerular mesangial cells: dependence on the Fc region of antibody. (1989) (26)
- Phosphorus-31 nuclear magnetic resonance studies of single muscle cells isolated from barnacle depressor muscle. (1983) (26)
- Nucleotide-binding oligomerization domain (NOD) signaling defects and cell death susceptibility cannot be uncoupled in X-linked inhibitor of apoptosis (XIAP)-driven inflammatory disease (2017) (25)
- Adenosine triphosphate activates the phospholipase-C cascade system in human amnion cells without increasing prostaglandin production. (1989) (25)
- Recruitment of purinergically stimulated Cl- channels from granule membrane to plasma membrane. (1996) (25)
- Basal and inducible expression of the thiol-sensitive ART2.1 ecto-ADP-ribosyltransferase in myeloid and lymphoid leukocytes (2009) (24)
- Elevation of cytosolic free calcium by platelet‐activating factor in cultured rat mesangial cells (1987) (24)
- Rapid effects ofphorbol ester on platelet shape change, cytoskeleton and calcium transient (1986) (24)
- Purinergic Receptors: Key Mediators of HIV-1 Infection and Inflammation (2015) (23)
- Focus on "extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells". (2002) (23)
- Activation of Inositol Phospholipid‐Specific Phospholipase C by P2‐Purinergic Receptors in Human Phagocytic Leukocytes (1990) (22)
- Induction of GLUT-1 mRNA in response to inhibition of oxidative phosphorylation: role of increased [Ca2+]i. (1996) (22)
- Calcium ionophore, A23187, induces commitment to differentiation but inhibits the subsequent expression of erythroid genes in murine erythroleukemia cells (1991) (21)
- Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes. (1994) (20)
- Stimulation of GLUT-1 glucose transporter expression in response to exposure to calcium ionophore A-23187. (1995) (20)
- Inhibition of GTP gamma S-dependent phospholipase D and Rho membrane association by calphostin is independent of protein kinase C catalytic activity. (1997) (19)
- Human β‐defensin‐3 structure motifs that are important in CXCR4 antagonism (2013) (19)
- Activation of the Inositol Phospholipid Signaling System by Receptors for Extracellular ATP in Human Neutrophils, Monocytes, and Neutrophil/Monocyte Progenitor Cells (1988) (19)
- Glucocorticoid uncoupling of antiogensin II-dependent phospholipase C activation in rat vascular smooth muscle cells. (1994) (19)
- Lipopolysaccharide, IFN-gamma, and IFN-beta induce expression of the thiol-sensitive ART2.1 Ecto-ADP-ribosyltransferase in murine macrophages. (2007) (19)
- The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation (2008) (18)
- Calcium-Independent Phospholipase A2β Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone (2009) (18)
- Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor–Dependent Death of Retinal Endothelial Cells (2016) (18)
- Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7 (2015) (17)
- Function without form: an ongoing search for maxi-anion channel proteins. Focus on "Maxi-anion channel and pannexin 1 hemichannel constitute separate pathways for swelling-induced ATP release in murine L929 fibrosarcoma cells". (2012) (16)
- Annexin II inhibition of G protein-regulated inositol trisphosphate formation in rat aortic smooth muscle. (1996) (16)
- ATP Release Mechanisms (2006) (16)
- Potent P2X7 receptor antagonists: Tyrosyl derivatives synthesized using a sequential parallel synthetic approach (2001) (16)
- Wear Particle-induced Priming of the NLRP3 Inflammasome Depends on Adherent Pathogen-associated Molecular Patterns and Their Cognate Toll-like Receptors: An In Vitro Study (2018) (16)
- The biologic actions of extracellular adenosine triphosphate. (1990) (15)
- Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IIalpha. (1998) (15)
- Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPalpha) DNA binding. (2000) (15)
- Functionalized congeners of tyrosine-based P2X(7) receptor antagonists: probing multiple sites for linking and dimerization. (2002) (13)
- Chemotherapy engages multiple pathways leading to IL-1β production by myeloid leukocytes (2014) (13)
- Role of P2 Receptors in the Immune System (2001) (12)
- Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes. (1998) (12)
- Up-regulated Ectonucleotidases in Fas-Associated Death Domain Protein– and Receptor-Interacting Protein Kinase 1–Deficient Jurkat Leukemia Cells Counteract Extracellular ATP/AMP Accumulation via Pannexin-1 Channels during Chemotherapeutic Drug-Induced Apoptosis (2017) (11)
- Na+/H+ Exchange in Ehrlich Ascites Tumor Cells (1986) (10)
- Calcium ionophore, A23187, induces commitment to differentiation but inhibits the subsequent expression of erythroid genes in murine erythroleukemia cells. (1991) (10)
- Focus on "Multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells". (1999) (9)
- Impairment of chemoattractant-stimulated hexose uptake in neonatal neutrophils. (1993) (9)
- Proceedings of Biological Actions of Extracellular ATP Conference Held in Philadelphia, Pennsylvania on 27-19 November 1990. (Annals of the New York Academy of Sciences. Volume 603) (1990) (9)
- Induction of incoordinate synthesis of muscle proteins by the tumor promoter TPA and the carcinogen EMS. (1985) (8)
- Renal sugar transport in the winter flounder. II. Galactose transport system. (1976) (8)
- CD40 in Endothelial Cells Restricts Neural Tissue Invasion by Toxoplasma gondii (2019) (7)
- Luciferase-assisted detection of extracellular ATP and ATP metabolites during immunogenic death of cancer cells. (2019) (7)
- Renal sugar transport in the winter flounder. III. Two glucose transport systems. (1977) (7)
- TH17 cells promote CNS inflammation by sensing danger signals via Mincle (2022) (6)
- Sarcoplasmic Ca2+ transients during the contractile cycle of single barnacle muscle fibres: measurements with arsenazo III-injected fibres (1982) (6)
- Cytosolic K+ and extracellular Na+ as regulators of NLRP3 inflammasome activation and the IL‐1β secretion response of macrophages to crystalline stimuli (2012) (6)
- CD8+CD73+ T cells in the tumor microenvironment of head and neck cancer patients are linked to diminished T cell infiltration and activation in tumor tissue (2020) (6)
- Lysosomal disruption by orthopedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms (2020) (5)
- Effects of sea nettle toxin on glucose transport in hamster intestine. (1974) (5)
- LipopolysaccharideBinding Site for Bacterial Lipid-Interaction Motifs Including a Potential Contains Multiple Protein-and 7 Cutting Edge : The Nucleotide Receptor P 2 X (2001) (5)
- Charge of the mito brigade. Focus on "Changes in mitochondrial surface charge mediate recruitment of signaling molecules during apoptosis". (2011) (5)
- Pyroptosis in neutrophils: Multimodal integration of inflammasome and regulated cell death signaling pathways (2023) (4)
- Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis (2023) (3)
- Dueling nucleosides: cross-regulation of extracellular adenosine by guanosine. Focus on "Extracellular guanosine regulates extracellular adenosine levels". (2013) (3)
- P2X7 Receptor‐dependent Secretion of IL‐1beta is Mediated by Exocytosis of Secretory Lysosomes (2007) (3)
- Inhibition of tension development and actomyosin ATPase activity in barnacle muscle by the Ca2+-indicator dye antipyrylazo III (1985) (3)
- Renal sugar transport in the winter flounder IV. Effect of CA2+ on sugar transport in teased renal tubules (1977) (3)
- Measurements of intracellular free Ca++. (1982) (2)
- Purinergic signal transduction: extracellular ATP and adenosine as agonists for receptor-mediated signaling (1993) (2)
- Flow Cytometric Measurements of Cytosolic [Ca2+] in Normal and Leukemic Progenitor Cells (1988) (2)
- Structure-Activity Relationships of Pyridoxal Phosphate Derivatives as Potent and Selective Antagonists of P 2 X 1 Receptors (2)
- Focus on "multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells". (1999) (2)
- Stimulation of cytosolic free calcium and contraction by immune complexes in cultured rat mesangial cells. (1987) (2)
- Multiple mechanisms for ATP release from apoptotic tumor cells (46.21) (2012) (1)
- The insulin like effects of vanadate on adipocyte sugar transport (1978) (1)
- The phlorizin effect on the transport of sugars at the antiluminal face of teased flounder tubules. (1977) (1)
- Erratum: The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation (Purinergic Signalling 10.1007/s11302-008-9095-1) (2008) (1)
- Gating of Pannexin 1‐Mediated ATP Release Channels by Mechanical Stress Stimuli (2011) (1)
- GPCRs in innate and adaptive immune responses (2020) (1)
- modulation by cyclic AMP and hyperphosphatemia extracellular pyrophosphate homeostasis: synergistic Regulation of vascular smooth muscle cell calcification by (2016) (1)
- Modulation of cytosolic free calcium by serum and phorbol myristate acetate in cultured rat mesangial cells (1987) (1)
- Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies (2022) (1)
- Microbes mediate mitochondrial misinformation to misguide neutrophils (2019) (1)
- release + receptor-mediated K 7 Mechanisms of caspase-1 activation by P2X (2016) (1)
- Micromolar concentrations of atp induce rapid increases in intracellular free calcium in ehrlich ascites tumor cells (1985) (0)
- The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo (2023) (0)
- via Caspase-8 in Dendritic Cells b of IL-1 Induce Noncanonical Processing and Release Proapoptotic Chemotherapeutic Drugs (2013) (0)
- NPP1 and NTPD1 activity and regulation in vascular smooth muscle cells (2007) (0)
- LPS‐Induced Expression of the Thiol‐Sensitive Ecto‐ADP‐ribosyltransferase 2.1 in Murine Macrophages (2007) (0)
- and influx 2 + efflux and Ca + disruption : roles for K lysosome disruption but inhibited by extensive lysosome NLRP 3 inflammasome signaling (2016) (0)
- Chemotherapeutic drugs trigger rapid apoptotic induction and caspase-1/ inflammasome signaling in murine macrophages (46.33) (2012) (0)
- Reversible modulation of erythrocyte Ca2+ homeostasis: a possible role for dialyzable plasma factors derived from patients with end-stage renal disease. (1989) (0)
- P2Y Purinergic Receptors (2004) (0)
- Influence of Cellular Magnesium Concentration on Fibroblast Phenotype Differentiation (2012) (0)
- Ecto-ADP-Ribosyltransferases in Murine Adenine Dinucleotide and Activation by Extracellular Nicotinamide Receptor 7 Differential Regulation of P 2 X Schilling and (2009) (0)
- Simultaneous measurements of membrane potential, sarcoplasmic free Ca++, and isometric tension in single barnacle muscle fibers injected with arsenazo III (1982) (0)
- Upregulated ectonucleotidases in FADD- and RIP1-deficient Jurkat leukemia cells counteract extracellular ATP/AMP accumulation via pannexin-1 channels during chemotherapeutic drug- induced apoptosis (2017) (0)
- Regulation of vascular calcification by endogenous ATP release coupled to extracellular pyrophosphate accumulation: Modulation by cAMP signaling (2009) (0)
- Molecular Mechanism of TRPV2 Channel Pore Dynamics during Ligand Activation (2018) (0)
- Ca++ measurements by antipyrylazo III (1978) (0)
- Autoinflammation in Diabetic Retinopathy (2011) (0)
- TH17 cells promote CNS inflammation by sensing danger signals via Mincle (2022) (0)
- Prolonged NLRP3 inflammasome activation enhances the secretion of autophagy‐derived vesicles containing LC3II in murine dendritic cells (2013) (0)
- hyperphosphatemia synergistic modulation by cyclic AMP and by extracellular pyrophosphate homeostasis: Regulation of vascular smooth muscle cell calcification (2010) (0)
- Contributors (1976) (0)
- N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis (2020) (0)
- Structural Insights into Ligand Modulation of the TRPV2 Channel (2019) (0)
- Extracellular pyrophosphate metabolism and calcification in (2011) (0)
- Mechanisms of ATP release from 1321N1 cells (2009) (0)
- Modulation of macrophage adherence by P2z purinergic receptors (1998) (0)
- differential regulation of P2X7R activation by extracellular NAD in murine macrophages and T cells (2009) (0)
- Pro‐apoptotic agents induce ATP release from leukemia/lymphoma tumor cells via pannexin‐1 dependent and pannexin‐1‐independent mechanism (2013) (0)
- Expression of P2X7 receptor splice variants is differentially regulated in macrophages versus T lymphocytes and is modulated by inflammatory cytokines (2011) (0)
- Role of p2 nucleotide receptors in inflammation and hematopoiesis (1999) (0)
- P2X7 receptor activation participates in high glucose‐induced caspase‐1 activation (2011) (0)
- on cellular mechanisms Ion homeostasis, channels, and transporters: an update (2015) (0)
- Pro-apoptotic chemotherapeutic drugs induce non-canonical processing and release of IL-1β via caspase-8 activation in dendritic cells (P1353) (2013) (0)
- Induction of p2z pnrinoreceptor-mediated phoipholipase d activity by lipopolyraccharide or interferon-gamma in a human monocytic cell line (1996) (0)
- Extracellular NAD Induced, P2x7 Pore Dependant ATP Release From Mouse Thymocytes (2007) (0)
- CELL DEATH AND INTERLEUKIN-1β RELEASE INDUCED BY TITANIUM PARTICLES DEPENDS ON LYSOSOMAL MEMBRANE DISRUPTION (2018) (0)
- Gating of Pannexin‐1 Channels by P2X7R‐Induced Inflammation or Apoptosis in Macrophages (2011) (0)
- signaling molecules during apoptosis'' mitochondrial surface charge mediate recruitment of . Focus on ''Changes in Charge of the mito brigade (2012) (0)
- Efflux + Is Dependent on K and Inflammasome and Caspase-1 Activation NLRP3/ASC Pneumolysin Is Mediated by the Processing Induced by b Neutrophil IL-1 (2015) (0)
- Release β and IL-1 Caspases , Activation of Rho-Effector Kinases , P 2 X 7 Receptor-Dependent Blebbing and the (2003) (0)
- Calcium Ionophore , A 23187 , Induces Commitment to Differentiation But Inhibits the Subsequent Expression of Erythroid Genes in Murine Erythroleukemia Cells (2003) (0)
- Highlight: A tasteful conversation with atypical mitochondria at atypical synapses (2018) (0)
- Signaling 2+ CaInflammasome Activation Independently of Efflux Agonists Induce NLRP3 +K (2015) (0)
- Decision letter: Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis (2020) (0)
- Micromolar concentrations of extracellular ATP induce rapid increases in intracellular free calcium in Ehrlich ascites tumor cells (1985) (0)
- Review for "Hypertonic saccharide solution delays pyroptosis in murine macrophages regardless of the membrane binding of gasdermin D N‐terminal" (2019) (0)
- Receptors | P2Y Receptors (2021) (0)
- The inflammatory effects of UDP-glucose in N9 microglia are not mediated by P2Y14 receptor activation (2008) (0)
- Preface (1990) (0)
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