George R. Pettit

Q: What Schools Are Affiliated With George R. Pettit

George R. Pettit is affiliated with the following schools: University of California, Berkeley, Washington State University, Kanagawa University, University of California, San Diego, Wayne State University, Stanford University, Osaka University of Pharmaceutical Sciences, University of Naples Federico II, Arizona State University, University of Bradford, University of Maine

George R. Pettit's AcademicInfluence.com Rankings

George R. Pettit

Chemistry

#1513

World Rank

#2252

Historical Rank

#557

USA Rank

chemistry Degrees

Download Badge

Chemistry

George R. Pettit's Degrees

PhD Chemistry University of California, Berkeley

Why Is George R. Pettit Influential?

(Suggest an Edit or Addition)

According to Wikipedia, George Robert Pettit II was a Regents’ Professor in Chemistry in the School of Molecular Sciences at Arizona State University. He was an internationally renowned and respected researcher in the field of natural anticancer compounds throughout his career of over six decades. Pettit has been honored by the International Cancer Advocacy Network, the American Society of Pharmacognosy, and Washington State University, his alma mater. A special edition of the Journal of Natural Products is dedicated to Pettit, and the French journal Médicine Sciences paid tribute to him. Pettit’s achievements earned him the designation of Outstanding Investigator by the United States National Institutes of Health National Cancer Institute . Pettit and his impact on the field of anti-cancer compounds are the subject of the book, “Waging War on Cancer.”

(See a Problem?)

George R. Pettit's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Isolation and structure of bryostatin 1 (1982) (649)
Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature. (1997) (634)
Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4 (1989) (577)
The isolation and structure of a remarkable marine animal antineoplastic constituent: dolastatin 10 (1987) (507)
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin. (1989) (380)
Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. (2000) (371)
Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data. (1991) (349)
Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a) (1995) (337)
Microplate Alamar Blue Assay for Staphylococcus epidermidis Biofilm Susceptibility Testing (2005) (316)
Isolation, structure, and synthesis of combretastatins A-1 and B-1, potent new inhibitors of microtubule assembly, derived from Combretum caffrum. (1987) (279)
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain. (1990) (268)
Anti-vascular approaches to solid tumour therapy: evaluation of combretastatin A4 phosphate. (1999) (265)
Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. (1990) (250)
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. (1988) (248)
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. (1987) (235)
Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts. (1994) (235)
Density functional study on the structural conformations and intramolecular charge transfer from the vibrational spectra of the anticancer drug combretastatin‐A2 (2009) (231)
Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs. (1995) (225)
In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug (1999) (211)
Antiviral (RNA) activity of selected Amaryllidaceae isoquinoline constituents and synthesis of related substances. (1992) (210)
Isolation and structure of combretastatin (1982) (201)
Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta (1995) (197)
Antineoplastic agents. 379. Synthesis of phenstatin phosphate. (1998) (190)
The interaction with tubulin of a series of stilbenes based on combretastatin A-4. (1995) (158)
Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C. (1988) (156)
Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp. (1991) (155)
Ubiquitination of Protein Kinase C-α and Degradation by the Proteasome* (1996) (155)
Phase I Study of Bryostatin 1: Assessment of Interleukin 6 and Tumor Necrosis Factor α Induction In Vivo (1993) (153)
Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41. (2005) (152)
Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate. (2002) (151)
The absolute configuration and synthesis of natural (−)-dolastatin 10 (1989) (150)
Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C. (1988) (144)
Isolation and structure of the powerful cell growth inhibitor cephalostatin 1 (1988) (144)
Antineoplastic agents, 120. Pancratium littorale. (1986) (144)
Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin. (1990) (141)
Bryostatins: potent, new mitogens that mimic phorbol ester tumor promoters. (1985) (138)
Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents. (1996) (138)
Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives. (2002) (138)
Isolation and Structure of the Cytostatic Linear Depsipeptide Dolastatin 15 (1989) (130)
The guanine nucleotide exchange factor RasGRP is a high -affinity target for diacylglycerol and phorbol esters. (2000) (124)
Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells. (1988) (124)
Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin. (1993) (123)
Antineoplastic agents 338. The cancer cell growth inhibitory. Constituents of Terminalia arjuna (Combretaceae). (1996) (123)
Progress in the discovery of biosynthetic anticancer drugs. (1996) (120)
Bryostatin 1 protects protein kinase C-delta from down-regulation in mouse keratinocytes in parallel with its inhibition of phorbol ester-induced differentiation. (1994) (119)
Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules. (1992) (118)
Antineoplastic agents, 122. Constituents of Combretum caffrum. (1987) (116)
Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products. (1994) (115)
Structure-cytotoxic activity relationship for the toad poison bufadienolides. (1998) (114)
Isolation and structure of the cancer cell growth inhibitor dictyostatin 1 (1994) (114)
Isolation of dolastatins 10–15 from the marine mollusc dolabella auricularia☆☆☆ (1993) (114)
Antineoplastic agents, 256. Cell growth inhibitory isocarbostyrils from Hymenocallis. (1993) (111)
Antineoplastic agents, 256. Cell growth inhibitory isocarbostyrils from Hymenocallis. (1993) (111)
Phase I study of bryostatin 1 in patients with relapsed non-Hodgkin's lymphoma and chronic lymphocytic leukemia. (1998) (111)
Antineoplastic agents. 520. Isolation and structure of irciniastatins A and B from the Indo-Pacific marine sponge Ircinia ramosa. (2004) (108)
Successful treatment of murine melanoma with bryostatin 1. (1991) (106)
Isolation and structure of five new cancer cell growth inhibitory bufadienolides from the Chinese traditional drug Ch'an Su. (2001) (104)
The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain. (1995) (101)
Three activators of protein kinase C, bryostatins, dioleins, and phorbol esters, show differing specificities of action on GH4 pituitary cells. (1986) (100)
Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA. (1992) (100)
Comparison of the Activities of the Truncated Halichondrin B Analog NSC 707389 (E7389) with Those of the Parent Compound and a Proposed Binding Site on Tubulin (2006) (97)
Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage. (2002) (92)
Antineoplastic agents. 443. Synthesis of the cancer cell growth inhibitor hydroxyphenstatin and its sodium diphosphate prodrug. (2000) (92)
The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1. (1998) (92)
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species. (2000) (91)
Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin. (2003) (91)
Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. (1994) (90)
Combination chemotherapy with combretastatin A-4 phosphate and 5-fluorouracil in an experimental murine colon adenocarcinoma. (2000) (89)
QSAR evaluation of the Ch'an Su and related bufadienolides against the colchicine-resistant primary liver carcinoma cell line PLC/PRF/5(1). (2002) (87)
Comparative Preclinical Pharmacokinetic and Metabolic Studies of the Combretastatin Prodrugs Combretastatin A4 Phosphate and A1 Phosphate (2004) (87)
NIR‐FT Raman and FT‐IR spectral studies and ab initio calculations of the anti‐cancer drug combretastatin‐A4 (2004) (87)
Isolation and Structure of Halistatin 1 from the Eastern Indian Ocean Marine Sponge Phakellia carteri (1993) (86)
ISOLATION AND STRUCTURE OF CONVOLUTAMYDINES B D FROM MARINE BRYOZOAN AMATHIA CONVOLUTA (1995) (84)
Inhibition of phorbol ester-induced T cell proliferation by bryostatin is associated with rapid degradation of protein kinase C. (1993) (84)
Antineoplastic agents, 105. Zephyranthes grandiflora. (1984) (84)
Partial parallelism and partial blockade by bryostatin 1 of effects of phorbol ester tumor promoters on primary mouse epidermal cells. (1987) (83)
The bryostatins. (1991) (83)
Notes- Potential Cancerocidal Agents. III. Formanilides. (1961) (82)
Isolation, structure, and synthesis of combretastatin A-2, A-3, and B-2 (1987) (81)
Varied differentiation responses of human leukemias to bryostatin 1. (1989) (79)
Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia (1989) (79)
Immunomodulating properties of a novel series of protein kinase C activators. The bryostatins. (1988) (79)
Marine animal biosynthetic constituents for cancer chemotherapy. (1981) (79)
A new anti-tubulin agent containing the benzo[b]thiophene ring system. (1999) (78)
Application of a high throughput Alamar blue biofilm susceptibility assay to Staphylococcus aureus biofilms (2009) (75)
Effects of the antimitotic natural product dolastatin 10, and related peptides, on the human malarial parasite Plasmodium falciparum. (2003) (74)
Bryostatin 1 and Phorbol Ester Down-Modulate Protein Kinase C-α and -ε via the Ubiquitin/Proteasome Pathway in Human Fibroblasts (1997) (74)
Antineoplastic agents. 450. Synthesis of (+)-pancratistatin from (+)-narciclasine as relay(1a). (2001) (73)
Bryostatin 1 down-regulates mdr1 and potentiates vincristine cytotoxicity in diffuse large cell lymphoma xenografts. (1998) (73)
Antineoplastic agents. 362. Isolation and X-ray crystal structure of dibromophakellstatin from the Indian ocean sponge Phakellia mauritiana. (1997) (73)
Isolation and structure of pancratistatin (1985) (72)
Preclinical evaluation of the antitumour activity of the novel vascular targeting agent Oxi 4503. (2002) (72)
Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification (1999) (72)
Isolation and structure of rolliniastatin 1 from the South American tree Rollinia mucosa (1987) (72)
Isolation and structure of the remarkable human cancer cell growth inhibitors spongistatins 2 and 3 from an eastern indian ocean Spongia sp. (1993) (71)
Isolation, structure, synthesis, and antimitotic properties of combretastatins B-3 and B-4 from Combretum caffrum. (1988) (71)
The dolastatins. (1997) (70)
Antineoplastic agents. 46. The isolation and structure of dolatriol (1976) (70)
Phorbol ester-stimulated phosphorylation of PU.1: association with leukemic cell growth inhibition. (1996) (70)
Dephosphorylation of activated protein kinase C contributes to downregulation by bryostatin. (1996) (70)
Synthesis and biological activity of some structural modifications of pancratistatin. (2004) (69)
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents. (2006) (69)
Oxi4503, a novel vascular targeting agent: effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate. (2003) (69)
Antineoplastic agents 337. Synthesis of dolastatin 10 structural modifications. (1995) (69)
Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction. (1996) (68)
Bryostatin 1 induces differentiation of B-chronic lymphocytic leukemia cells. (1989) (68)
Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix. (2003) (68)
Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin. (2000) (67)
Antineoplastic agents. 410. Asymmetric hydroxylation of trans-combretastatin A-4. (1999) (67)
Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro. (1988) (66)
Bryostatin 1 and phorbol ester down-modulate protein kinase C-alpha and -epsilon via the ubiquitin/proteasome pathway in human fibroblasts. (1997) (66)
Antineoplastic agents 429. Syntheses of the combretastatin A-1 and combretastatin B-1 prodrugs. (2000) (66)
Isolation and structure of the marine sponge cell growth inhibitory cyclic peptide phakellistatin 1. (1993) (66)
A β‐Carboline‐1‐one Mimic of the Anticancer Amaryllidaceae Constituent Pancratistatin: Synthesis and Biological Evaluation (2004) (66)
In vitro evaluation of the antineoplastic activity of combretastatin A-4, a natural product from Combretum caffrum (arid shrub) (1993) (65)
Isolation and structure of the cell growth inhibitory depsipeptides dolastatins 11 and 12 (1989) (65)
Antineoplastic agents. 3. Structure of the cyclic peptide dolastatin 3 from Dolabella auricularia (1982) (65)
Demonstration of sub-nanomolar affinity of bryostatin 1 for the phorbol ester receptor in rat brain. (1988) (65)
Binding of [26-3H]bryostatin 1 and analogs to calcium-dependent and calcium-independent protein kinase C isozymes. (1994) (65)
Isolation and structure of ruprechstyril from Ruprechtia tangarana. (2003) (64)
Antineoplastic agents. 485. Isolation and structure of cribrostatin 6, a dark blue cancer cell growth inhibitor from the marine sponge Cribrochalina sp. (2003) (64)
Antineoplastic agents, 162. Zephyranthes candida. (1990) (63)
Marine animal and terrestrial plant anticancer constituents (1994) (62)
Isolation and structures of schleicherastatins 1-7 and schleicheols 1 and 2 from the teak forest medicinal tree Schleichera oleosa. (2000) (62)
Dolastatin 11, a marine depsipeptide, arrests cells at cytokinesis and induces hyperpolymerization of purified actin. (2001) (62)
Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity. (1993) (61)
The Marine Product Cephalostatin 1 Activates an Endoplasmic Reticulum Stress-specific and Apoptosome-independent Apoptotic Signaling Pathway* (2006) (61)
Antineoplastic agents. 551. Isolation and structures of bauhiniastatins 1-4 from Bauhinia purpurea (2006) (61)
Inhibition by bryostatin 1 of the phorbol ester-induced blockage of differentiation in hexamethylene bisacetamide-treated Friend erythroleukemia cells. (1987) (60)
Antineoplastic agents. 340. Isolation and structural elucidation of bryostatins 16-18. (1996) (60)
Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore. (2001) (60)
Interaction of halichondrin B and homohalichondrin B with bovine brain tubulin. (1993) (60)
Novel cytotoxic diterpenes from Casearia arborea. (2000) (59)
Activation and growth of murine tumor-specific T-cells which have in vivo activity with bryostatin 1. (1992) (59)
Structure of bryostatin. 4. An important antineoplastic constituent of geographically diverse Bugula neritina (Bryozoa) (1984) (59)
The role of protein kinase C isoenzymes in the growth inhibition caused by bryostatin 1 in human A549 lung and MCF‐7 breast carcinoma cells (1994) (58)
Isolation of labradorins 1 and 2 from Pseudomonas syringae pv. coronafaciens. (2002) (58)
Phase I study of bryostatin 1: assessment of interleukin 6 and tumor necrosis factor alpha induction in vivo. The Cancer Research Campaign Phase I Committee. (1993) (58)
Antineoplastic agents 389. New syntheses of the combretastatin A-4 prodrug. (1998) (57)
Isolation and structure of a 20,21-epoxybufenolide series from "Ch'an Su". (2002) (57)
Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10. (1990) (57)
Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C. (1996) (57)
Antineoplastic agents, 99. Amaryllis belladonna. (1984) (56)
The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1. (1996) (56)
Ubiquitination of protein kinase C-alpha and degradation by the proteasome. (1996) (56)
Field ionization mass spectrometry—III: Cardenolides (1971) (56)
Successful treatment of human Waldenström's macroglobulinemia with combination biological and chemotherapy agents. (1994) (55)
Antineoplastic agents 365. Dolastatin 10 SAR probes. (1998) (55)
Isolation and structure of cytostatic steroidal saponins from the African medicinal plant Balanites aegyptica. (1991) (54)
Comparison of effects of bryostatins 1 and 2 and 12-O-tetradecanoylphorbol-13-acetate on protein kinase C activity in A549 human lung carcinoma cells. (1989) (54)
Antineoplastic Agents. 277. Isolation and Structure of Phakellistatin 3 and Isophakellistatin 3 from a Republic of Comoros Marine Sponge (1994) (54)
Convolutamides A ∼ F, novel γ-lactam alkaloids from the marine Bryozoan Amathia convoluta (1994) (54)
Antitumour evaluation of dolastatins 10 and 15 and their measurement in plasma by radioimmunoassay (1996) (54)
The structure of bryostatin 2 from the marine bryozoan bugula neritina (1983) (54)
Interaction of dolastatin 10 with tubulin: induction of aggregation and binding and dissociation reactions. (1995) (54)
Bryostatin 1 induces apoptosis and augments inhibitory effects of vincristine in human diffuse large cell lymphoma. (1995) (53)
The Dolastatins. 17. Synthesis of Dolaproine and Related Diastereoisomers (1994) (53)
The structure and synthesis of dolastatin 3 (1987) (52)
Antineoplastic agents 100: The marine bryozoan Amathia convoluta1 (1985) (52)
Antineoplastic agents. 206. Structure of the cytostatic macrocyclic lactone combretastatin D-2 (1990) (51)
Isolation and structure of bryostatins 10 and 11 (1987) (51)
Interactions of Halichondrin B and Eribulin with Tubulin (2011) (51)
Action of phorbol esters, bryostatins, and retinoic acid on cholesterol sulfate synthesis: relation to the multistep process of differentiation in human epidermal keratinocytes. (1989) (51)
Isolation and structure of stylostatin 1 from the Papua New Guinea marine sponge Stylotella aurantium (1992) (51)
Antineoplastic agents. 551. Isolation and structures of bauhiniastatins 1-4 from Bauhinia purpurea. (2006) (50)
Isolation and structure of the powerful human cancer cell growth inhibitors spongistatins 4 and 5 from an African Spirastrella spinispirulifera(porifera) (1993) (50)
The discovery and development of the combretastatins (2005) (50)
Antineoplastic agents, 325. Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 from Phakellia sp. (1995) (49)
Effects of bryostatins and retinoic acid on phorbol ester- and diacylglycerol-induced squamous differentiation in human tracheobronchial epithelial cells. (1989) (49)
Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,). (2008) (49)
Antineoplastic agents 393. Synthesis of the trans-isomer of combretastatin A-4 prodrug. (1998) (49)
In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity. (1993) (49)
Spongistatin 1: a new chemosensitizing marine compound that degrades XIAP (2008) (49)
A broad-spectrum antifungal from the marine sponge Hyrtios erecta. (1997) (48)
Evaluation of limonoids against the murine P388 lymphocytic leukemia cell line. (1983) (48)
Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. (2003) (48)
Antineoplastic agents. 278. Isolation and structure of axinastatins 2 and 3 from a western Caroline Island marine sponge. (1994) (48)
Antineoplastic agents. 220 Sybthesis of natural (-)-dolastatin 15 (1991) (47)
Amino Acids and Derivatives (1975) (47)
Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography. (2003) (47)
Antineoplastic agents, 118. Isolation and structure of bryostatin 9. (1986) (46)
Successful treatment of human chronic lymphocytic leukemia xenografts with combination biological agents auristatin PE and bryostatin 1. (1998) (46)
Bryostatin 1-induced hairy cell features on chronic lymphocytic leukemia cells in vitro. (1993) (46)
Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate. (2002) (46)
Synthesis of the dolastatin thiazole amino acid component (gln)Thz (1985) (45)
Antineoplastic agents, 301. An investigation of the Amaryllidaceae genus Hymenocallis. (1995) (45)
Field ionization mass spectrometry—I. Nucleosides (1969) (45)
The bcl-2 and p53 oncoproteins can be modulated by bryostatin 1 and dolastatins in human diffuse large cell lymphoma. (1995) (45)
Isolation and structural modification of 7-deoxynarciclasine and 7-deoxy-trans-dihydronarciclasine. (2006) (45)
Antineoplastic agents, 177. Isolation and structure of phyllanthostatin 6. (1990) (45)
Antineoplastic agents, 301. An investigation of the Amaryllidaceae genus Hymenocallis. (1995) (45)
Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cells. (1987) (43)
Antineoplastic agents. 398. Isolation and structure elucidation of cephalostatins 18 and 19. (1998) (43)
Combretastatin A-1 phosphate a novel tubulin-binding agent with in vivo anti vascular effects in experimental tumours. (2002) (43)
Isolation and structure of the human cancer cell growth inhibitory cyclodepsipeptide dolastatin 16. (1997) (43)
Antineoplastic agents. 190. Isolation and structure of the cyclodepsipeptide dolastatin 14 (1990) (43)
Antineoplastic agents. 509: synthesis of fluorcombstatin phosphate and related 3-halostilbenes(1). (2005) (43)
Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent. (2013) (42)
Antineoplastic agents. 168. Isolation and structure of axinohydantoin (1990) (42)
Synthesis of natural (-)-combretastatin (1985) (42)
An orthotopic model of human pancreatic cancer in severe combined immunodeficient mice: potential application for preclinical studies. (1998) (42)
Specific Activities of Dolastatin 10 and Peptide Derivatives against Cryptococcus neoformans (1998) (42)
Antineoplastic agents. 193. Isolation and structure of the cyclic peptide hymenistatin 1 (1990) (41)
Isolation and structure of bryostatins 14 and 15 (1991) (41)
The Catalytic Domain of Protein Kinase Cδ Confers Protection from Down-regulation Induced by Bryostatin 1* (1997) (41)
Antineoplastic agents, 103. The isolation and structure of hypoestestatins 1 and 2 from the East African Hypoëstes verticillaris. (1984) (41)
Vibrational spectra and ab initio molecular orbital calculations of the novel anti-cancer drug combretastatin A-4 prodrug. (2008) (41)
Antineoplastic agents. 126. Isolation and structure of bryostatins 12 and 13 (1987) (41)
The isolation and structure of aplysistatin. (1977) (40)
Antineoplastic agents. 380. Isolation and X-ray crystal structure determination of isoaaptamine from the Republic of Singapore Hymeniacidon sp. and conversion to the phosphate prodrug hystatin 1. (2004) (40)
Isolation and structure of bryostatins 5–7 (1985) (40)
Antineoplastic agents 300. Isolation and structure of the rare human cancer inhibitory macrocyclic lactones spongistatins 8 and 9 (1994) (40)
Cephalostatin 1 Inactivates Bcl-2 by Hyperphosphorylation Independent of M-Phase Arrest and DNA Damage (2005) (39)
Development of an in vitro analogue of initiated mouse epidermis to study tumor promoters and antipromoters. (1990) (39)
Antineoplastic agents. 454. Synthesis of the strong cancer cell growth inhibitors trans-dihydronarciclasine and 7-deoxy-trans-dihydronarciclasine (1a). (2009) (39)
Antineoplastic agents 440. Asymmetric synthesis and evaluation of the combretastatin A-1 SAR probes (1S,2S)- and (1R,2R)-1, 2-dihydroxy- 1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3' ',4' ',5' '-trimethoxyphenyl)-ethane. (2000) (39)
Antineoplastic agents. 527. Synthesis of 7-deoxynarcistatin, 7-deoxy-trans-dihydronarcistatin, and trans-dihydronarcistatin 1(1). (2005) (38)
Isolation and structure of the unusual Indian Ocean Cephalodiscus gilchristi components, cephalostatins 5 and 6l (1989) (38)
Isolation and structure of cephalostatins 10 and 11. (1994) (38)
Antineoplastic agents 293. The exceptional human cancer cell growth inhibitors spongistatins 6 and 7 (1993) (38)
Antineoplastic agents. 93. Structure of the Bugula neritina (marine bryozoa) antineoplastic component bryostatin 3 (1983) (38)
A pinacol rearrangement/oxidation synthetic route to hydroxyphenstatin. (2000) (38)
Antineoplastic agents. 214. Isolation and structure of cephalostatins 7-9 (1992) (38)
Interaction of dolastatin 10 with bovine brain tubulin. (1992) (37)
Antineoplastic agents. 104. Isolation and structure of the Phyllanthus acuminatus Vahl (Euphorbiaceae) glycosides (1984) (37)
E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes. (2009) (37)
Synthesis of the 6- and 7-hydroxy-5,8-dioxocarbostyrils. (1968) (37)
Isolation and structure of palstatin from the amazon tree Hymeneae palustris (2003) (37)
Differential effects of various protein kinase C activators on protein phosphorylation in human acute myeloblastic leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a. (1987) (37)
Isolation and structure of hemibastadinols 1-3 from the Papua New Guinea marine sponge Ianthella basta. (1996) (36)
Antineoplastic agents. 489. Isolation and structures of meliastatins 1-5 and related euphane triterpenes from the tree Melia dubia (2002) (36)
Magnetic Resonance Imaging to Measure Therapeutic Response Using an Orthotopic Model of Human Pancreatic Cancer (2000) (36)
Steroids and Related Natural Products. XI. Reduction of Esters to Ethers1-3 (1962) (36)
Differential effects of bryostatin 1 on human non-Hodgkin's B-lymphoma cell lines. (1993) (36)
Cell growth inhibitory dihydrophenanthrene and phenanthrene constituents of the African tree Combretum caffrum (1988) (36)
Dolastatin 10 and dolastatin 15: effects of two natural peptides on growth and differentiation of leukemia cells. (1992) (36)
The isolation of loliolide from an Indian Ocean opisthobranch mollusc. (1980) (35)
Antineoplastic agents. 542. Isolation and structure of sesterstatin 6 from the Indian Ocean sponge Hyrtios erecta. (2005) (35)
Differential effects of bryostatins and phorbol esters on arachidonic acid metabolite release and epidermal growth factor binding in C3H 10T1/2 cells. (1988) (35)
Isolation and structure of combretastatin D-1: a cell growth inhibitory macrocyclic lactone from Combretum caffrum (1988) (35)
Isolation and structure of phakellistatin 14 from the Western Pacific marine sponge Phakellia sp. (2005) (34)
Isolation and structure of rolliniastatin 2: A new cell growth inhibitory acetogenin from Rollinia mucosa (1989) (34)
Antineoplastic agents. 570. Isolation and structure elucidation of bacillistatins 1 and 2 from a marine Bacillus silvestris. (2009) (34)
Bryostatin 1 antagonizes the terminal differentiating action of 12-O-tetradecanoylphorbol-13-acetate in a human colon cancer cell. (1988) (34)
Isolation and structure of cribrostatins 1 and 2 from the blue marine sponge Cribrochalina sp. (1992) (34)
Antineoplastic agents. 592. Highly effective cancer cell growth inhibitory structural modifications of dolastatin 10. (2011) (34)
Antineoplastic Agents. 510. Isolation and structure of dolastatin 19 from the Gulf of California sea hare Dolabella auricularia. (2004) (34)
Synthesis and biological evaluation of fully synthetic bryostatin analogues (1998) (34)
Bryostatin 1: a potential anti-leukemic agent for chronic myelomonocytic leukemia. (1991) (34)
Isolation and Crystal Structure of Stylopeptide 1, A New Marine Porifera Cycloheptapeptide (1995) (34)
Antineoplastic agents. 534. isolation and structure of sansevistatins 1 and 2 from the African Sansevieria ehrenbergii. (2005) (33)
Human THP-1 monocytic leukemic cells induced to undergo monocytic differentiation by bryostatin 1 are refractory to proteasome inhibitor-induced apoptosis. (2000) (33)
Isolation and structure of the exceptional Pterobranchia human cancer inhibitors cephalostatins 16 and 171 (1995) (33)
Antineoplastic agents. 558. Ampelocissus sp. cancer cell growth inhibitory constituents. (2008) (33)
Binding of [3H]bryostatin 4 to protein kinase C. (1992) (33)
Isolation and structure of the cytostatic lignan glycoside phyllanthostatin A. (1988) (33)
Synthesis of the Marine Sponge Cycloheptapeptide Phakellistatin 51 (2000) (33)
Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted α,β-unsaturated sulfoxide (2000) (33)
Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity. (2000) (33)
Antineoplastic agents. 553. The Texas grasshopper Brachystola magna. (2005) (32)
Antineoplastic agents. 545. Isolation and structure of turbostatins 1-4 from the Asian marine mollusk Turbo stenogyrus. (2005) (32)
Co-induction of lymphokine synthesis by the antineoplastic bryostatins. (1987) (32)
Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents. (2008) (32)
Antineoplastic agents 285.' Isolation and structures of cephalostatins 14 and 15 (1994) (32)
Antineoplastic agents. 57. Isolation and structure of aphanastatin (1978) (32)
Antibacterial activity of the marine sponge constituent cribrostatin 6. (2004) (32)
Antineoplastic agents. 61. Isolation and structure of amoorastatin (2002) (32)
Dolastatins. 26. Synthesis and stereochemistry of dolastatin 11 (1997) (31)
Antineoplastic agents 491. Synthetic conversion of aaptamine to isoaaptamine, 9-demethylaaptamine, and 4-methylaaptamine. (2004) (31)
Antineoplastic agents. 397: Isolation and structure of sesterstatins 4 and 5 from Hyrtios erecta (the Republic of Maldives). (1998) (31)
Comparative antitumor activities of halichondrins and vinblastine against human tumor xenografts. (1996) (31)
Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri (1993) (31)
A cobalt-phosphine complex directed Reformatsky approach to a stereospecific synthesis of the dolastatin 10 unit dolaproine (Dap). (2001) (31)
Differential roles of the tandem C1 domains of protein kinase C delta in the biphasic down-regulation induced by bryostatin 1. (1999) (31)
Steroids and Related Natural Products. VIII. Synthesis of Oxasteroids1,2 (1961) (31)
Isolation, structure, and synthesis of combretastatin C-1 (1989) (30)
Antineoplastic agents, 294. Variations in the formation of pancratistatin and related isocarbostyrils in Hymenocallis littoralis. (1995) (30)
Antineoplastic agents, 294. Variations in the formation of pancratistatin and related isocarbostyrils in Hymenocallis littoralis. (1995) (30)
Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta (1999) (30)
Anticancer Drugs from Animals, Plants, and Microorganisms (1994) (30)
Antineoplastic agents 390. Isolation and structure of phakellistatin 12 from a Chuuk archipelago marine sponge. (1994) (30)
Aluminum Chloride-Catalyzed Opening of the Steroidal Sapogenin Spiroketal System1 (1960) (30)
Differentiation and growth modulation of chronic myelogenous leukemia cells by bryostatin. (1990) (30)
Biosynthetic Products for Cancer Chemotherapy. Vol. 1 (1977) (29)
Conformational analysis of a marine antineoplastic macrolide, bryostatin 10☆ (1996) (29)
Cyclotrimerization approach to unnatural structural modifications of pancratistatin and other amaryllidaceae constituents — Synthesis and biological evaluation (2006) (29)
Rhinovirus inhibition by bufadienolides. (1988) (29)
The structure of amoorastatone and the cytotoxic limonoid 12-hydroxyamoorastatin (1979) (29)
Positron emission tomography of murine liver metastases and the effects of treatment by combretastatin A-4 (1999) (28)
Biosynthetic Products for Cancer Chemotherapy (1978) (28)
Auristatin PYE, a novel synthetic derivative of dolastatin 10, is highly effective in human colon tumour models. (2007) (28)
Antineoplastic agents. 556. Isolation and structure of Coprinastatin 1 from Coprinus cinereus. (2010) (28)
Intracellular Activation and Deactivation of Tasidotin, an Analog of Dolastatin 15: Correlation with Cytotoxicity (2009) (28)
Hydrogen Bromide-Acetic Acid Demethylation of 2,3-Dimethoxy-6-bromobenzoic Acid. An Example of Concomitant Bromine Migration1,2 (1960) (28)
Antineoplastic agents. Part 409: Isolation and structure of montanastatin from a terrestrial actinomycete. (1999) (27)
Characterization of the Hollow Fiber Assay for the Determination of Microtubule Disruption In vivo (2004) (27)
Reaction of the Steroidal Sapogenin Spiroketal System with Ethanedithiol1 (1959) (27)
Communications: Formylation of Aromatic Amines with Dimethylformamide (1959) (27)
Isolation and structure of the hemichordate cell growth inhibitors cephalostatins 2, 3, and 4 (1988) (27)
The antineoplastic bryostatins affect human basophils and mast cells differently. (1995) (26)
Antineoplastic agents 470. Absolute configuration of the marine sponge bromopyrrole agelastatin A. (2005) (26)
Antineoplastic agents. 522. Hernandia peltata (Malaysia) and Hernandia nymphaeifolia (Republic of Maldives). (2004) (26)
Antineoplastic agents. 511. Direct phosphorylation of phenpanstatin and pancratistatin. (2004) (25)
The transient increase of tight junction permeability induced by bryostatin 1 correlates with rapid downregulation of protein kinase C-alpha. (2000) (25)
Phorbol ester augments butyrate‐induced apoptosis of colon cancer cells (1996) (25)
In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-beta-D-arabinofuranosylcytosine in human leukemia cells. (1991) (25)
Antineoplastic Agents. 595. Structural Modifications of Betulin and the X-ray Crystal Structure of an Unusual Betulin Amine Dimer1 (2014) (25)
Effects of dolastatins on human B-lymphocytic leukemia cell lines. (1993) (25)
Isolation and Structure of 14,15β-Epoxyprieurianin From the South American Tree Guarea guidona (1982) (25)
Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1 (2003) (24)
Effect of the protein kinase C activating agent bryostatin 1 on the clonogenic response of leukemic blast progenitors to recombinant granulocyte-macrophage colony-stimulating factor. (1991) (24)
In Vitro Activities of Two Antimitotic Compounds, Pancratistatin and 7-Deoxynarciclasine, againstEncephalitozoon intestinalis, a Microsporidium Causing Infections in Humans (2001) (24)
Unusual Antimicrotubule Activity of the Antifungal Agent Spongistatin 1 (1999) (24)
Isolation and X-ray crystal structure of racemic Xestospongin D from the Singapore marine sponge Niphates sp1 (1996) (24)
Isolation and structure of the symmetrical disteroidal alkaloids cephalostatin 12 and cephalostatin 13 (1994) (24)
Isolation and structure of gustastatin from the Brazilian nut tree Gustavia hexapetala. (2004) (24)
Contrasting duration of inhibition of cell-cell communication in primary mouse epidermal cells by phorbol 12,13-dibutyrate and by bryostatin 1. (1988) (24)
Antineoplastic agents. 561. Total synthesis of respirantin. (2007) (23)
Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation. (1991) (23)
Dolastatin 15 induces apoptosis and BCL-2 phosphorylation in small cell lung cancer cell lines. (1998) (23)
Effects of bryostatins 1 and 2 on morphological and functional differentiation of SH-SY5Y human neuroblastoma cells. (1990) (23)
Bryostatin 1 modulates the proliferation and lineage commitment of human myeloid progenitor cells exposed to recombinant interleukin-3 and recombinant granulocyte-macrophage colony-stimulating factor. (1992) (23)
The crystal and molecular structure of the unusual spiro dihydrofuran diterpene nepetaefolin. (1975) (23)
Bryostatin 1-activated T cells can traffic and mediate tumor regression. (1992) (23)
Antineoplastic agents. 400. Synthesis of the Indian Ocean marine sponge cyclic heptapeptide phakellistatin 2. (1999) (23)
Mimicry of bryostatin 1 induced phosphorylation patterns in HL-60 cells by high-phorbol ester concentrations. (1988) (23)
Role of Smac in cephalostatin-induced cell death (2008) (23)
Isolation and structures of axistatins 1-3 from the Republic of Palau marine sponge Agelas axifera Hentschel . (2013) (23)
Synthesis of phakellistatin 11: a micronesia (Chuuk) marine sponge cyclooctapeptide. (2001) (22)
Desulfurization with Raney Nickel. II. Sulfonamides1,2 (1962) (22)
Antineoplastic agents. 386. Isolation of sesterstatins 1-3 from the marine sponge Hyrtios erecta (1998) (22)
Synergistic interaction of selected marine animal anticancer drugs against human diffuse large cell lymphoma (1998) (22)
Antineoplastic agents. 499. Synthesis of hystatin 2 and related 1H-benzo[de][1,6]-naphthyridinium salts from aaptamine. (2004) (22)
Direct Photoaffinity Labeling by Dolastatin 10 of the Amino-terminal Peptide of β-Tubulin Containing Cysteine 12* (2004) (22)
Antineoplastic agents 360. Synthesis and cancer cell growth inhibitory studies of dolastatin 15 structural modifications. (1998) (22)
Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. (2009) (22)
Comparison of the antitumor activity of bryostatins 1, 5, and 8 (1995) (22)
SYNTHESIS OF THE MARINE SPONGE CYCLOHEPTAPEPTIDE STYLOPEPTIDE 1 (1996) (22)
Antineoplastic agents 315. Isolation and structure of the marine sponge cancer cell growth inhibitor phakellistatin 5 (1994) (22)
Synthesis and biological evaluation of a spongistatin AB-spiroketal analogue. (2002) (22)
Combretastatin A-4, an agent that displays selective toxicity towards tumour vasculature (1997) (22)
Antineoplastic agents. 552. Oxidation of combretastatin A-1: trapping the o-quinone intermediate considered the metabolic product of the corresponding phosphate prodrug. (2008) (22)
Combretastatin A-1 phosphate potentiates the antitumour activity of cisplatin in a murine adenocarcinoma model. (2003) (21)
Synthesis of bufalitoxin and bufotoxin (1987) (21)
Letter: The structure of carminomycin I. (1975) (21)
Isolation and structure of axinastatin 5 from a republic of comoros marine sponge (1994) (21)
The antineoplastic quassinoids of Simaba cuspidata spruce and Ailanthus grandis Prain. (1980) (21)
An improved source of bryostatin 10, Bugula neritina from the Gulf of Aomori, Japan. (1995) (21)
Steroids and related natural products—xxvii. Salvia apiana (1966) (21)
Isolation and structure of dolastatin 17 (1998) (21)
The Dolastatins 20. A Convenient Synthetic Route to Dolastatin 15 (1994) (21)
Stylopeptide 2, a proline-rich cyclodecapeptide from the sponge Stylotella sp. (2008) (21)
The Dolastatins. 19. Synthesis of Dolaisoleuine (1994) (21)
Characterization of Cardenolides by Field Ionization Mass Spectrometry (1970) (20)
Isolation and structure of axinastatin 4 from the western indian ocean marine sponge Axinella cf. carteri (1993) (20)
Sterols of marine invertebrates. 63. Isolation and structure elucidation of sutinasterol, the major sterol of the marine sponge Xestospongia sp (1991) (20)
Antineoplastic agents, 326. The stereochemistry of bastadins 8, 10, and 12 from the Bismarck archipelago marine sponge Ianthella basta. (1995) (20)
The cephalostatins. 21. Synthesis of bis-steroidal pyrazine rhamnosides (1). (2011) (20)
Isolation and structure of pedilstatin from a Republic of maldives Pedilanthus sp.1 (2002) (20)
Bufadienolides. 11. Bufalin and resibufogenin. (1970) (20)
Isolation and structure of the human cancer cell growth inhibitory cyclic decapeptides phakellistatins 7, 8 and 91,2 (1995) (20)
Stimulation of phosphatidylcholine synthesis by activators of protein kinase C is dissociable from increased phospholipid hydrolysis. (1991) (20)
Antineoplastic agents. 224. Isolation and structure of neristatin 1 (1991) (20)
Antineoplastic agents 370. Isolation and structure of dolastatin 18 (1997) (19)
The structures of phyllanthostatin 1 and phyllanthoside from the Central American tree Phyllanthusacuminatus Vahl (1982) (19)
Antineoplastic agents. Part 395.1 Isolation and structure of agelagalastatin from the Papua New Guinea marine sponge Agelas sp. (1999) (19)
Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification. (2009) (19)
Antimicrobial and cancer cell growth inhibitory activities of 3β-acetoxy-17β-(l-prolyl)amino-5α-androstane in vitro (2000) (19)
Antineoplastic Agents. 585. Isolation of Bridelia ferruginea Anticancer Podophyllotoxins and Synthesis of 4-Aza-podophyllotoxin Structural Modifications. (2016) (19)
Isolation and structure of halistatin 3 from the Western Pacific (Chuuk) marine sponge Phakellia sp (1995) (19)
Synthesis of water-soluble sugar derivatives of combretastatin A-4 (1995) (19)
The isolation and structure of 13,18-dehydroglaucarubinone, a new antineoplastic quassinoid from Simarouba amara. (1978) (19)
Bufobutanoic acid and bufopyramide, two new indole alkaloids from the Chinese traditional drug Ch'an Su (1999) (19)
The dolastatins; 18: Stereospecific synthesis of dolaproine (1996) (18)
Antineoplastic agents. 565. Synthesis of combretastatin D-2 phosphate and dihydro-combretastatin D-2. (2009) (18)
Dolastatins 24: synthesis of (–)-dolastatin 10. X-Ray molecular structure of N,N-dimethylvalyl-valyl-dolaisoleuine tert-butyl ester (1996) (18)
Isolation and structure of the human cancer cell growth inhibitory phakellistatin 4 from the western Pacific sponge Phakellia costata (1995) (18)
Antineoplastic agents. 34. Helenium autumnale L. (1974) (18)
Anti neoplastic agents. CCLII. Isolation and structure of Halistatin 2 from the Comoros marine sponge Axinella carteri (1993) (18)
Synthesis of 10b(R)-hydroxypancratistatin, 10b(S)-hydroxy-1-epipancratistatin, 10b(S)-hydroxy-1,2-diepipancratistatin and related isocarbostyrils (2002) (18)
Antineoplastic agents. 535. Isolation and structure of plakorstatins 1 and 2 from the Indo-Pacific sponge Plakortis nigra. (2004) (18)
PROTON MAGNETIC RESONANCE CHEMICAL SHIFTS OF THE S-METHYL GROUP (1964) (18)
Steroids and Related Natural Products. VI. The Structure of α-Apoallobetulin1,2 (1961) (18)
An Improved Procedure for the Preparation of Alkyl Halide Derivatives of Saccharin (1954) (18)
The macrocyclic lactone protein kinase C activator, bryostatin 1, either alone, or in conjunction with recombinant murine granulocyte-macrophage colony-stimulating factor, protects Balb/c and C3H/HeN mice from the lethal in vivo effects of ionizing radiation. (1994) (18)
Structure of an antineoplastic agent from Streptomyces griseoluteus. (1976) (18)
First generation design, synthesis, and evaluation of azepine-based cryptophycin analogues. (2001) (18)
Immunomodulation in patients receiving intravenous Bryostatin 1 in a phase I clinical study: comparison with effects of Bryostatin 1 on lymphocyte function in vitro (1994) (17)
Antineoplastic agents 320: synthesis of a practical pancratistatin prodrug. (1995) (17)
Bufadienolides. 5. Synthesis of cardenolides. (1970) (17)
Expression of proto-oncogene c-jun during differentiation of B-chronic lymphocytic leukemia. (1990) (17)
A new tubulin polymerization inhibitor, auristatin PE, induces tumor regression in a human Waldenstrom's macroglobulinemia xenograft model. (1999) (17)
Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4. (2008) (17)
Steroids and related natural products. LIV. Bufadienolides. 7. Synthesis of 3.beta.-acetoxy-5.alpha.-l4.alpha.-bufa-20,22-dienolide (1970) (17)
Neristatin 1 Provides Critical Insight into Bryostatin 1 Structure–Function Relationships (2015) (17)
Regulation of hematopoiesis-IV: The role of interleukin-3 and bryostatin 1 in the growth of erythropoietic progenitors from normal and anemic W/Wv mice. (1988) (17)
Communications- Steroids and Related Natural Products. IV. Reduction of Lactones to Cyclic Ethers. (1961) (17)
Antineoplastic agents, 88. Pimelea prostrata. (1983) (17)
Modulation of mediator release from human basophils and pulmonary mast cells and macrophages by auranofin. (1990) (17)
Design, synthesis, and evaluation of azepine-based cryptophycin mimetics (2003) (17)
Synthetic conversion of bryostatin 2 to bryostatin 1 and related bryopyrans (1991) (17)
Phorbol ester and bryostatin differentially regulate the hydrolysis of phosphatidylethanolamine in Ha-ras- and raf-oncogene-transformed NIH 3T3 cells. (1991) (17)
Phorbol esters activate proteoglycan metabolism in human colon cancer cells en route to terminal differentiation. (1990) (17)
Isolation of human cancer cell growth inhibitory, antimicrobial lateritin from a mixed fungal culture. (2010) (16)
Effect of Auristatin PHE on Microtubule Integrity and Nuclear Localization in Cryptococcus neoformans (2002) (16)
Bryostatin 1-tamoxifen combinations show synergistic effects on the inhibition of growth of P388 cells in vitro. (1998) (16)
Structural biochemistry. VI. Synthesis of 2′-(l-prolyl-l-prolyl)emetine (1967) (16)
Clonal preservation of human pancreatic cell line derived from primary pancreatic adenocarcinoma. (1999) (16)
Effect of a combined exposure to cytosine arabinoside, bryostatin 1, and recombinant granulocyte-macrophage colony-stimulating factor on the clonogenic growth in vitro of normal and leukemic human hematopoietic progenitor cells. (1992) (16)
The isolation and structure of phyllanthostatins 2 and 3 (1982) (16)
In Vitro Activities and Postantifungal Effects of the Potent Dolastatin 10 Derivative Auristatin PHE (2001) (16)
Antineoplastic agents. 81. The glycerol ethers of Palythoa liscia (1982) (16)
Antineoplastic agents. 550. Synthesis of 10b(s)-epipancratistatin from (+)-narciclasine. (2007) (16)
Biosynthesis of the antineoplastic pancratistatin following tissue culture of Hymenocallis littoralis (Amaryllidaceae) (1992) (16)
Antineoplastic agents 385. The isolation and structure of a scalarane-type sesterterpene from the Indian Ocean porifera Hyrtios erecta (1998) (15)
(+)-Phorboxazole A synthetic studies. Identification of a series of highly cytotoxic C(45-46) analogues. (2005) (15)
Antineoplastic agents. 200. Absolute configuration of the bryostatins (1991) (15)
Steroids and related natural products. 64. Reduction of .delta.-lactones and hindered esters with diborane (1971) (15)
Reduction of the steroidal sapogenin spiroketal system (1973) (15)
The Reaction of α-Halo Ketones with 2-Pyridinethiol1 (1954) (15)
Steroids and related natural products-X: reduction of lactones (1962) (15)
The cephalostatins. 22. synthesis of bis-steroidal pyrazine pyrones (1). (2012) (15)
Antineoplastic agents. 571. Total synthesis of bacillistatin 2. (2009) (15)
The isolation and structure of 13,18-dehydroglaucarubinone, a new antineoplastic quassinoid fromSimarouba amara (1978) (14)
CHAPTER 12 – BIOSYNTHETIC PRODUCTS FOR ANTICANCER DRUG DESIGN AND TREATMENT: THE BRYOSTATINS (2002) (14)
Synthesis of (±)-Isocombretastatins A-C (1987) (14)
Bufadienolides. 26. Synthesis of scillarenin. (1974) (14)
Antineoplastic agents. 599. Total synthesis of dolastatin 16. (2015) (14)
Spiroketal reductive ring opening (1972) (14)
Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp. (2002) (14)
Isolation and structure of pedilstatin from a republic of maldives Pedilanthus sp. (2002) (14)
Antineoplastic Agents. 554. The manitoba bacterium Streptomyces sp. (2006) (14)
Synthesis and biological evaluation of phorboxazole congeners leading to the discovery and preparative-scale synthesis of (+)-chlorophorboxazole a possessing picomolar human solid tumor cell growth inhibitory activity. (2008) (14)
Synthesis of (7S,15S)- and (7R,15S)-dolatrienoic acid. (2001) (14)
Antineoplastic agents 453. Synthesis of pancratistatin prodrugs. (2000) (14)
Crystal Conformation of the Cyclic Decapeptide Phakellistatin 8: Comparison with Antamanide (1997) (14)
Antineoplastic agents. 560. Isolation and structure of kitastatin 1 from an Alaskan Kitasatospora sp. (2007) (14)
Bufadienolides. 13. Conversion of 3 beta-hydroxy-17-oxoandrost-5-ene to 3 beta-acetoxy-5 beta, 14 alpha-bufa-20,22-dienolide. (1971) (13)
Synthesis of the Dolastatin 3 Isomer cyclo-[L-Pro-L-Leu-L-Val-(-R,S)-(gln)Thz-(gly)Thz] (1986) (13)
High resolution mass spectrometry. Bufadienolides—II. (1972) (13)
Isolation of geodiastatins 1 and 2 from the marine sponge Geodia mesotriaena. (1981) (13)
Isolation of the nickel-chlorin chelate tunichlorin from the South Pacific ocean sea hare Dolabella auricularia. (1993) (13)
Broad scope secondary ion mass spectrometry (1983) (13)
The Cephalostatins. 24. Isolation, Structure, and Cancer Cell Growth Inhibition of Cephalostatin 20. (2015) (13)
Synthesis and in vitro cancer cell growth inhibitory activity of monocyclic model compounds containing spongistatin triene side-chains. (1998) (13)
Structural biochemistry. IV. 3β-Hydroxy-17β-(l-prolyl)amino-androst-5-ene (1967) (13)
Bufadienolides. 3. A synthetic route to isocardenolides. (1970) (13)
Design and synthesis of a potent phorboxazole C(11-15) acetal analogue. (2006) (13)
Antineoplastic agents. 590. X-ray crystal structure of dolastatin 16 and syntheses of the dolamethylleuine and dolaphenvaline units. (2011) (13)
Preclinical study of dolastatin-10 in dogs with spontaneous neoplasia (2002) (13)
Synthesis of the cyclo-[(gly)Thz-(R)-and cyclo-[(gly)Thz-(S)-(gln)Thz-L-Val-L-Leu-L-Pro] isomers of dolastatin 3 (1985) (13)
Preclinical efficacy of sodium narcistatin to reduce inflammation and joint destruction in rats with adjuvant-induced arthritis (2012) (13)
Antineoplastic agents. 587. Isolation and structure of 3-epipancratistatin from Narcissus cv. Ice Follies. (2012) (13)
Synthesis of tobacco mosaic virus protein sequence 81-85. (1971) (13)
Communications- Steroids and Related Natural Products. II. A Method for the Direct Conversion of Esters to Ethers (1960) (12)
Structure of the principal antineoplastic glycosides of Phyllanthusacuminatus Vahl (1983) (12)
Antineoplastic agents. 529. Isolation and structure of nootkastatins 1 and 2 from the Alaskan yellow cedar Chamaecyparis nootkatensis. (2004) (12)
Bufadienolides. 21. Synthesis of cinobufagin from bufotalin. (1972) (12)
Antineoplastic agents 157. Quassia kerstingII1 (1988) (12)
Antineoplastic agents. 55. Isolation and structure of multigilin and multistatin (1978) (12)
Phyllanthostatin 1-Phyllanthoside Orthoacid Rearrangement (1985) (12)
Synthesis of 10b-R-hydroxy-pancratistatin via narciclasine (1994) (12)
Antineoplastic agents XLV: sea cucumber cytotoxic saponins. (1976) (12)
The 1H and 13C NMR Chemical Shift Assignments for Thirteen Bufadienolides Isolated from the Traditional Chinese Drug Ch'an Su (2001) (12)
A CHEMIFLUORESCENT IMMUNOASSAY FOR THE DETERMINATION OF MARINOBUFAGENIN IN BODY FLUIDS (2011) (12)
Antineoplastic agents 582. Part 1: Isolation and structure of a cyclobutane-type sesquiterpene cancer cell growth inhibitor from Coprinus cinereus (Coprinaceae). (2010) (12)
Isolation and structure of angasiol (1978) (12)
Effect of bryostatin 1 on the in vitro radioprotective capacity of recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) toward committed human myeloid progenitor cells (CFU-GM). (1992) (12)
Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1. (2011) (12)
Structural effects in mass spectrometry. Mechanistic implications in the dehydration of 26-hydroxy-5.alpha.-furostan by six- and seven-membered cyclic transition states (1970) (12)
Chiral modifications of dolastatin 10: the potent cytostatic peptide (19aR)-isodolastatin 10. (1990) (12)
Cytostatic Effects of Dolastatin 10 and Dolastatin 15 on Human Leukemia Cell Lines (1992) (12)
Antineoplastic agents. 386. Isolation of sesterstatins 1-3 from the marine sponge Hyrtios erecta. (1998) (11)
Steroids and related natural products. VII. Boron trifluoride etherate-lithium aluminum hydride reduction of smilagenin acetate (1961) (11)
Antineoplastic Agents. VI. Mannich Base Nitrogen Mustards (Part B)1-3 (1962) (11)
The protein kinase C pathway in tumor promotion. (1989) (11)
Isolation and characterization of palystatins A-D. (1982) (11)
Reaction of phenols with acetic anhydride – dimethyl sulfoxide (1967) (11)
Synthesis of the modified dolastatin 3 sequence cyclo -[L-Val-L-Leu-L-Pro-(R ,S )-(gln)Thz-(gly)Thz] (1986) (11)
Antineoplastic agents 460. Synthesis of combretastatin A-2 prodrugs. (2001) (11)
Field ionization mass spectrometry—II: Benzyloxycarbonyl and t‐butyloxycarbonyl derivatives of some simple peptides (1970) (11)
Activity of Selected Amaryllidaceae Constituents and Related Synthetic Substances Against Medically Important RNA Viruses (1992) (11)
Bufadienolides. 4. Reaction of 20-oxo steroids with methoxymethylenetriphenylphosphorane. (1970) (11)
Synthesis and X-ray crystal structure of the dolabellaauricularia peptide dolastatin 18. (2004) (11)
Structural modifications of bryostatin 2. (1992) (11)
Antineoplastic agents, 116. An evaluation of the marine ascidian Aplidium californicum. (1986) (11)
The Dolastatins. 21. Synthesis, X-ray Crystal Structure, and Molecular Modeling of (6R)-Isodolastatin 10 (1994) (11)
Antineoplastic agents 500. Narcistatin. (2003) (11)
Steroids and Related Natural Products. XII. Fomes applanatus1, 2 (1962) (11)
Modulation of cIAP-1 by novel antitubulin agents when combined with bryostatin 1 results in increased apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh. (1999) (11)
Antineoplastic Agents. Part 189. The Absolute Configuration and Synthesis of Natural (-)-Dolastatin 10. (1989) (11)
Bufadienolides. 1. Introduction and base-catalyzed condensation of methyl ketones with glyoxylic acid. (1970) (10)
Combretastatin-A 4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly ( ADP-ribose ) Polymerase Cleavage 1 (2002) (10)
Antineoplastic and cytotoxic components of desert Baileya. (1975) (10)
Bryostatin 1 induces ubiquitin COOH-terminal hydrolase in acute lymphoblastic leukemia cells. (1996) (10)
A PROTON MAGNETIC RESONANCE STUDY OF N-BIS(2-HALOETHYL)AMINES (1965) (10)
Antineoplastic agents. 76. The sea urchin Strongylocentrotus droebachiensis. (1981) (10)
Bufadienolides. 6. Synthesis of 17-beta-(6'-alpha-pyronyl)androstanes. (1970) (10)
Antineoplastic Agents. 603. Quinstatins: Exceptional Cancer Cell Growth Inhibitors. (2017) (10)
Effect of phorbol and bryostatin I on chondrogenic expression of chick limb bud, in vitro. (1987) (10)
ANTINEOPLASTIC AGENTS: X. N-BIS(2-FLUOROETHYL)AMINES (1964) (10)
Antineoplastic agents. 515. Synthesis of human cancer cell growth inhibitors derived from 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene. (2005) (10)
Dolastatin 11 conformations, analogues and pharmacophore. (2005) (10)
Non‐iterative Asymmetric Synthesis of C15 Polyketide Spiroketals (2004) (10)
Modulation of the activity of a human granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein (pIXY 321) by the macrocyclic lactone protein kinase C activator bryostatin 1. (1993) (10)
The Isolation and Structure Elucidation of Debromoaxinohydantoin (1995) (10)
In vitro and in vivo antifungal activities of the marine sponge constituent spongistatin. (2005) (10)
In vivo activity of anprocide alone, and in vitro activity in combination with conventional antibiotics against Staphylococcus aureus and Staphylococcus epidermidis biofilms. (2009) (10)
High-performance liquid chromatographic assay for the novel antitumor drug, bryostatin-1, incorporating a serum extraction technique. (1998) (10)
Synthesis of the marine sponge cycloheptapeptide phakellistatin 5(1). (2000) (10)
Dolastatins 23: stereospecific synthesis of dolaisoleuine (1996) (9)
Antineoplastic agents 540. The Indian Gynandropsis gynandra (Capparidaceae). (2005) (9)
Steroids and related natural products. 85. Bufadienolides. 26. Direct conversion of 14-dehydrobufalin to bufalin (1973) (9)
Arizona flora: The sterols of Peniocereus greggii☆ (1969) (9)
Synthesis of buf-20(21)-enolides and bufa-20,22-dienolides (1969) (9)
STRUCTURAL BIOCHEMISTRY: II. SYNTHESIS OF 3β-HYDROXY-17β (L-PROLYL-L-PROLYL)AMINO-5α-ANDROSTANE (1966) (9)
Structural biochemistry 15--mass spectrometry of permethylated nucleotides. (1978) (9)
Antineoplastic agents. Par 108. Structural biochemistry. Part 23. Synthesis of the dolastatin thiazole amino acid component (gln)Thz (1985) (9)
Steroids and related natural products. 90. 15beta-Hydroxydigitoxigenin. (1975) (9)
Bufadienolides. 29. Synthetic routes to bufotalin. (1974) (9)
Synthesis of the cyclic heptapeptides axinastatin 2 and axinastatin 3 (1996) (9)
Structure of nitroarginine. A nitrogen-15 nuclear magnetic resonance study (1979) (9)
REACTION OF AMINES WITH DIMETHYLTHIOFORMAMIDE (1965) (9)
The inhibitory effects of bryostatin 1 administration on the growth of rabbit papillomas. (1999) (9)
Antineoplastic agents. 488. Isolation and structure of yukonin from a yukon territory fungus. (2003) (9)
Synthesis of azotomycin (1986) (8)
ANTINEOPLASTIC AGENTS. V. THE AROMATIC SYSTEM OF PODOPHYLLOTOXIN (PART B). (1962) (8)
An efficient synthetic strategy for obtaining 4-methoxy carbon isotope labeled combretastatin A-4 phosphate and other Z-combretastatins. (2010) (8)
Structure and stereochemistry of the monobromotigogenins (1964) (8)
Bufadienolides. 8. 12(13--14)abeo skeletal rearrangements. (1970) (8)
Antineoplastic agents. 573. isolation and structure of papilistatin from the papilionid butterfly Byasa polyeuctes termessa. (2010) (8)
Antineoplastic agents. 43. Structure of carminomycin I (1975) (8)
Synthesis of 2′-(N′-bis(2-chloroethyl)glycyltryptophyl)emetine and related peptides (1967) (8)
Antineoplastic agents. 489. Isolation and structures of meliastatins 1-5 and related euphane triterpenes from the tree Melia dubia. (2002) (8)
Lyngbyastatin 1 and Ibu-epilyngbyastatin 1: synthesis, stereochemistry, and NMR line broadening. (2002) (8)
Potentiation of the activity of cisplatin in a human colon tumour xenograft model by auristatin PYE, a structural modification of dolastatin 10. (2010) (8)
Intramolecular condensation reactions of 1,1,3,3-tetrakis(2-chloroethyl)urea (1970) (8)
SEPARATION OF TOAD POISON BUFADIENOLIDES BY HYDROPHOBIC GEL (1999) (8)
Synthesis of L-(5-chloro-2-pyridyl)glycine (1979) (8)
Differential expression of TRAP Isoenzyme in B-CLL Cells Treated with Different Inducers. (1990) (8)
Mass measurements of natural products by solution phase secondary ion mass spectrometry employing silver(I) and thallium(I) derivatives (1984) (8)
Bufadienolides. 30. Synthesis of the Ch'an Su component 15beta-hydroxybufalin. (1975) (8)
Synthesis of bufalin (1970) (8)
Differential Gene Expression in Auristatin PHE-Treated Cryptococcus neoformans (2004) (8)
Synthesis of the Streptomyces ambofaciens antineoplastic constituent 6-diazo-5-oxo-L-norleucine (1983) (8)
Establishment of a murine leukaemia cell line resistant to the growth-inhibitory effect of bryostatin 1. (1994) (8)
Antineoplastic agents. XIX. N-Bis(2-haloethyl)glycine amides (1967) (8)
Desulfurization with Raney Nickel (2011) (8)
Assignment of Quaternary Carbons in Aromatic Compounds by Long-range Heteronuclear Shift Correlated 2D-NMR Spectroscopy and Its Application to Acteoside (1987) (8)
Steroids and related natural products-XVII: conversion of lanosterol to 14α-methyl steroids (1963) (8)
The Dolastatins. 22. Synthesis Of Boc-Dolaproinyl Dolaphenine and Four Related Chiral Isomers (1994) (8)
Potential Cancerocidal Agents. I. The Aromatic System of Podophyllotoxin (Part A)1,2 (1960) (8)
The Cephalostatins. 23. Conversion of Hecogenin to a Steroidal 1,6-Dioxaspiro[5.5]nonane Analogue for Cephalostatin 11. (2015) (7)
Synthesis of 3β-Acetoxy-17β-(L-Arginyl-L-Arginyl-L-Prolyl)Amino-5α-Androstane (1967) (7)
Structural biochemistry. Part VIII. 9-Amino-(9-deoxy)-cinchona alkaloids (1968) (7)
Antineoplastic agents 463. Synthesis of combretastatin A-3 diphosphate prodrugs. (2000) (7)
Synthesis of 2-dialkylamino-6- and -7-hydroxy-5,8-dioxoquinolines. (1971) (7)
Bufadienolides. 14. Synthesis of bufotalien, 15 -hydroxybufalin, and resibufogenin. (1971) (7)
Communications- Steroids and Related Natural Products. VI. Diborane Reduction of Lactones to Cyclic Hemiacetals (1961) (7)
Antineoplastic agents. 36. Crystal and molecular structure of the pseudoguaianolide autumnolide (1975) (7)
Antineoplastic agents. 53. The crystal structure of radiatin (1978) (7)
Antineoplastic agents. 36. Acetylenic carrier groups. (1974) (7)
Antineoplastic agents LXIV: 1,4-Bis(2'-chloroethyl)-1,4-diazabicyclo[2.2.1]heptane dihydrogen dimaleate. (1979) (7)
Bufadienolides. 17. Synthesis of 14α- and 14β-Artebufogenin (1973) (7)
Isolation and Structure of Cancer Cell Growth Inhibitory Tetracyclic Triterpenoids from the Zimbabwean Monadenium lugardae. (2016) (7)
The isolation of isosakuranetin methyl ether from Eupatorium odoratum (1978) (7)
High Performance Liquid Chromatographic Separation of Bryostatins 1–12 (1989) (7)
Separation of pyrroloimidazoles from indo-pacific marine sponges by high-speed countercurrent distribution (1989) (7)
Separation of Bufotalin and Cinobufotalin by Preparative Liquid Chromatography (1987) (6)
Binding of [26-3H]-epi-bryostatin 4 to protein kinase C. (1991) (6)
Steroids and related natural products. 66. Structural modification of the triterpene A ring. (1972) (6)
ANTINEOPLASTIC AGENTS: XI. N-BIS(2-BROMOETHYL)AMINES (1964) (6)
Higher Plant Terpenoids (1977) (6)
Antineoplastic agents. 548. Synthesis of iodo- and diiodocombstatin phosphate prodrugs. (2012) (6)
Arthropod antineoplastic agent. (1968) (6)
Antineoplastic agents. 251. Isolation and structure of stylostatin 1 from the Papua New Guinea marine sponge Stylotella sp. [Erratum to document cited in CA118(5):36157a] (1993) (6)
Steroids and related natural products. 69. Synthesis of 20(22)-dihydro-23-deoxodigitoxigenin. (1972) (6)
Antineoplastic agents. 67. Senecio fendleri Gray. (1980) (6)
Antineoplastic agents 442. Synthesis and biological activities of dioxostatin. (2000) (6)
Antineoplastic Agents. XVIII. N-(2-Haloethyl)benzylamines (1967) (6)
Characterization of a novel cdk1-related kinase. (1999) (6)
Antineoplastic Agents. 605. Isoquinstatins. (2017) (6)
Communications. Steroids and Related Natural Products. III. 4-Oxasteroids. (1961) (6)
In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium. (1992) (6)
Synthesis of amino acid diazoketones (1986) (6)
Structural biochemistry. Part XII. Synthesis of tobacco mosaic virus protein unit 150–158 (1973) (6)
ANTINEOPLASTIC AGENTS. IV. MANNICH BASE NITROGEN MUSTARDS (PART A). (1962) (6)
Antineoplastic Agents. 606. The Betulastatins. (2018) (6)
Bufadienolides. 27. Synthesis of telocinobufagin. (1974) (6)
Synthesis of the 14α- and 16α-epimers of bufotalin acetate and 16-deacetylcinobufagin (1988) (6)
Steroids and related natural products. Part XLII. 14α-Methyl cholestanes (1967) (6)
Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida (1997) (6)
Antineoplastic agents. 48. The isolation and structure of aplysistatin (1977) (6)
Steroids and related natural products. XVI synthesis of oxaestranes (1963) (5)
The Dolastatins 16. Synthesis of Dolaphenine (1994) (5)
ANTINEOPLASTIC AGENTS: IX. N-BENZYL-N-BIS(2-HALOETHYL)AMINES (1963) (5)
Stimulation of arachidonic acid release and prostaglandin synthesis by bryostatin 1. (1988) (5)
Antineoplastic agents. 575. the fungus Aspergillus phoenicis (2009) (5)
Antineoplastic Agents 78. Isolation of Palystatins 1-3 From the Indian Ocean Palythoa liscia (1982) (5)
Synthesis of 5α-cinobufagin (1987) (5)
Isolation and characterization of lytechinastatin (1981) (5)
Steroids and related natural products. 96. Synthesis of 3.beta.,16.beta.,23(R),26-Tetrahydroxy-5.beta.-cholestane (1978) (5)
Evolutionary Biosynthesis of Anticancer Drugs (2001) (5)
Stability-indicating high-performance liquid chromatography assay for the anticancer drug bryostatin 1. (1989) (5)
Antineoplastic agents. 58. Synthesis of 3-aryl-5-bromo-2(5H)-furanones (1978) (5)
Synthesis of hydroxyhydrolapachol and lapachol (1971) (5)
Structural biochemistry. 20. Methylation of purine nucleosides (1980) (5)
A View of Cancer Treatment in the People's Republic of China (1976) (5)
The structure of the benzene―maleimide photosynthetic product (mitindomide) (1983) (5)
Single crystal x-ray structures of chemotherapeutic agents. 3. Structure of 1,4-diazabicyclo[2.2.1]heptanes, a new heterocyclic ring system. (1971) (5)
Selective Methylation of Nucleosides1 (1980) (5)
Antineoplastic Agents. 604. The Path of Quinstatin Derivatives to Antibody Drug Conjugates. (2017) (4)
Antineoplastic Agents. Part 277. Isolation and Structure of Phakellistatin 3 and Isophakellistatin 3 from a Republic of Comoros Marine Sponge. (1994) (4)
Butterfly wing antineoplastic agents (1972) (4)
Structure of bis(2-chloroethyl)ammonium hexachlorostannate. (1992) (4)
Structural biochemistry. 17. Synthesis of tryptophan dipeptides. (2009) (4)
Modulation by bryostatin 1 of the in vitro radioprotective effects of the GM-CSF/IL-3 fusion protein, PIXY 321, on normal human myeloid progenitors. (1993) (4)
Steroids and related natural products. LVI. Bufadienolides. 9. Isobufalin (1970) (4)
Procedures for the analyses of dolastatins 10 and 15 by high performance liquid chromatography (1994) (4)
A New Anti‐Tubulin Agent Containing the Benzo[b]thiophene Ring System. (1999) (4)
Isolation of geodiatoxins 2-4 from the marine sponge Geodia mesotriaena. (1990) (4)
Isolation and Characterization of Strongylostatin 1 (1979) (4)
Tumor Promotion: A Problem of Differential Responses of Normal and Neoplastic Cells to Trophic Stimuli (1987) (4)
Interaction of diazonamide a with tubulin. (2019) (4)
Conversion of tetracyclic triterpenes to steroids (1969) (4)
Total Synthesis and Biological Evaluation of Amaryllidaceae Alkaloids : Narciclasine , ent-7-Deoxypancratistatin , Regioisomer of 7-Deoxypancratistatin , 10 b-epi-Deoxypancratistatin , and Truncated Derivatives 1 (4)
Steroids and related natural products. 70. Conversion of cardenolides to isocardanolides. (1972) (4)
The scientific contributions of Jonathan L. Hartwell, Ph.D (1995) (4)
Potential Cancerocidal Agents. II. Synthesis of 6,7-Methylenedioxycarbostyril1 (1960) (4)
Transformation of digitoxigenin to scillarenin. (1972) (4)
The structure of the steroid toad venom constituent bufotoxin (1972) (4)
Antineoplastic Agents. 607. Emetine Auristatins. (2020) (4)
Steroids and related natural products. 94 Synthesis of toad venom cardenolides. (1977) (4)
Antineoplastic agents. XXIV. 1,4-Bis(2-chloroethyl)-1,4-diazoniabicyclo[2.2.1]heptane diperchlorate (1969) (4)
Antineoplastic agents 596. Isolation and structure of chromomycin A5 from a Beaufort Sea microorganism (2015) (4)
Bufadienolides-19. 3β-acetoxy-15-oxo-5β,14β-bufa-8,20,22-trienolide (1975) (4)
Antineoplastic Agents. Part 395. Isolation and Structure of Agelagalastatin from the Papua New Guinea Marine Sponge Agelas sp. (1999) (4)
Bryostatin 1 induces productive Epstein-Barr virus replication in latently infected cells: implications for use in immunocompromised patients (2004) (4)
Introduction and Glossary (1975) (3)
Structural Biochemistry 14. Permethylation of Nucleosides (1977) (3)
Synthesis and in vitro antimetabolic evaluation of some steroidal thiazoles (1989) (3)
The structure of 3β-acetoxy-15α-(o-nitrobenzoyl)oxy-5β,14β-bufa-8,20,22-trienolide (1982) (3)
Conformational Analysis of a Marine Antineoplastic Macrolide, Bryostatin 10. (1996) (3)
Steroids and related natural products. 63. 17-beta-acetoxy-4-oxa-2-androstene. (1970) (3)
Bufadienolides. 32. Selenium dioxide dehydrogenation of 14-dehydrobufalin (1982) (3)
Antineoplastic Agents. Part 252. Isolation and Structure of Halistatin 2 from the Comoros Marine Sponge Axinella carteri (1993) (3)
Antineoplastic agents. XXV. 1,4-Diazabicyclo [2.2.1] heptanes. (1969) (3)
Antineoplastic agents, 178. Isolation and structure of lychnostatins 1 and 2 from the South American Lychnophora antillana. (1990) (3)
Preparation of elastothiomers with a phase transfer catalyst (1980) (3)
STEROIDS AND RELATED NATURAL PRODUCTS. 98. CONVERSION OF CYCLOHEXANONE TO SPIRO(3,4-CYCLOHEXANO-4-HYDROXYBICYCLO(3.3.1)NONAN-9-ONE-2,1′-CYCLOHEXANE) (1981) (3)
Circular Dichroism of Bufadienolides (1985) (3)
Bufadienolides. 10. 3-beta-acetoxy-14-beta,21-epoxy-5-beta-bufanolide and related lactones. (1970) (3)
Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6. [Erratum to document cited in CA122:290568] (1995) (3)
Convolutamides A ≅ F, Novel γ-Lactam Alkaloids from the Marine Bryozoan Amathia convoluta. (1995) (3)
Microtubule depolymerization in Uromyces appendiculatus by three new antineoplastic drugs: combretastatin A-4, dolastatin 10 and halichondrin B (1998) (3)
Synthesis of 6-hydroxy-5,8-dioxo-7-(9-hydroxy-9'-n-pentyltetradecyl)carbostyril. (1968) (3)
ANTINEOPLASTIC AGENTS: XV. INTRAMOLECULAR REACTIONS OF N-PHENYL-N′-BIS(2-CHLOROETHYL)UREA (1965) (3)
Antineoplastic Agents. VIII. Bis(2-chloroethyl)amine Condensation Reactions. Part A1,2 (1962) (3)
Erratum: Isolation and structure of the hemichordate cell growth inhibitors cephalostatins 2,3, and 4 (Journal of the Chemical Society, Chemical Communications (1988) (865)) (1988) (3)
Antineoplastic Agents. Part 292. Isolation and Structure of the Exceptional Pterobranchia Human Cancer Inhibitors Cephalostatins 16 and 17. (1996) (3)
Steroids and related natural products. 88. Synthesis of periplogenin. (1974) (3)
Antineoplastic agents. 600. From the South Pacific Ocean to the silstatins. (2015) (3)
Antineoplastic agents. 52. Baileya multiradiata. (1978) (3)
Steric Requirements in the Cyclization of Naphthalene Derivatives (1957) (3)
Steroids and related natural products. 98. Conversion of cyclohexanone to spiro[3,4-cyclohexano-4-hydroxybicyclo[3.3.1]nonan-9-one-2,1'-cyclohexane] (1981) (3)
Antineoplastic agents. 109. Structural biochemistry. 24. Synthesis of the cyclo-[(gly)Thz-(R)- and (S)-(gln)Thz-L-Val-L-Leu-L-Pro] isomers of dolastatin 3 (2002) (3)
Steroids and related natural products. XLIX. Bufadienolides. 2. 20-Hydroxy-21-nor-5.alpha.-cholanic acid .gamma.-lactones (24.far.20) (1970) (3)
Convolutamines A-E, Novel .BETA.-Phenylethylamine Alkaloids from Marine Bryozoan Amathia convoluta. (1995) (3)
Stability of the 1,4-bis(2′-haloethyl)-1,4-diazabicyclo[2.2.1]heptane dication (1981) (3)
Antineoplastic agents. 47. Structure of an antineoplastic agent from Streptomyces griseoluteus (1977) (3)
Synthesis of isobufalin methyl ester (1967) (3)
Bufadienolides. Part XXIII. 14,15β-epoxy-3β,11α-dihydroxy-5β-bufa-20,22-dienolide (11α-hydroxyresibufogenin) (1973) (3)
Steroids and Related Natural Products. IX. Selective Osmium Tetroxide Oxidation of Olefins1,2 (1961) (2)
The crystal structure of 3β-hydroxy-4α,23R,24R-trimethyl-5α-cholestane (23R,24R-5α-dinostanol) from dinoflagellates1 (1986) (2)
Structure of the bufadienolide bufotalin (1970) (2)
STEROIDS AND RELATED NATURAL PRODUCTS: XXVIII. STEREOCHEMISTRY OF 3-HYDROXY-4-OXA-5α-CHOLESTANE AND RELATED HEMIACETALS (1966) (2)
Anti-cancer peptide (1995) (2)
Conformational Preference of Two Toad Poison Bufadienolides, Cinobufagin and Bufotalin (1998) (2)
Erratum: Isolation and structure of five new cancer cell growth inhibitory bufadienolides from the Chinese traditional drug Ch'an Su (Journal of Natural Products (2004) 64 (1148-1151)) (2004) (2)
Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase II gene expression in human leukemia cells. (1991) (2)
Antineoplastic agents 32. The pseudoguaianolide helenalin (1973) (2)
Synthesis of 10b‐R‐Hydroxypancratistatin via Narciclasine. (1995) (2)
Structural biochemistry. V. Diarginyl steroidal peptides (1967) (2)
Biosynthetic product molecular weight determinations by solution phase secondary ion mass spectrometry employing group 1A metal salts (1985) (2)
Isolation and structural elucidation of 3,6-dioxo-hexahydro-pyrrolo [1,2-a]-pyrazine from the echinodermLuidia clathrata (1973) (2)
Efficient Separation of Dolaproine Stereoisomers by Optimization of a Three Component Chromatographic Solvent System (1990) (2)
ANTINEOPLASTIC AGENTS PART 37, CRSTAL AND MOLECULAR STRUCTURE OF THE PSEUDOGUAIANOLIDE AUTUMNOLIDE (1975) (2)
Synthesis of a Spirovetivane Synthon1 (1981) (2)
Steroids and related natural products—XXII : Oxidation of 3β-acetoxy-5α-lanostane (1964) (2)
DESULPHURIZATION WITH RANEY NICKEL III. BENZYL N-ALKYL-N-BENZENESULPHONYLCARBAMATES (1963) (2)
Correction- Steroids and Related Natural Products. VI. The Structure of α-Apoallobetulin (1961) (2)
Antineoplastic Agents. Part 491. Synthetic Conversion of Aaptamine to Isoaaptamine, 9-Demethylaaptamine, and 4-Methylaaptamine. (2004) (2)
An Improved Procedure for Liquid Solid Chromatography (1976) (2)
Antineoplastic agents. XXVIII. Camptothecin .delta.-lactone (1972) (2)
Bufadienolides. XX. 14β-Chloro-bufadienolides (1973) (2)
Three New Alkaloids, Convolutamines F and G, and Convolutamydine E, from the Floridian Marine Bryozoan Amathia convoluta. (1999) (2)
Steroids and related natural products. 79. Reaction of 3.beta.-acetoxy-8.alpha., 9.alpha.-oxido-5.alpha.-lanostane with Grignard reagents (1972) (2)
Conversion of steroidal δ-lactones into dihydropyrans or tetrahydropyrans (1970) (2)
Convolutamydine A, a Novel Bioactive Hydroxyindole Alkaloid from Marine Bryozoan Amathia convoluta (1995) (1)
Discovery and Development of Therapeutic Drugs against Lethal Human RNA Viruses: a Multidisciplinary Assault. (1990) (1)
Isolation and structure of palstatin from the Amazon tree Hymeneae palustris(1). (2003) (1)
Antineoplastic Agents. Part 220. Synthesis of Natural (-)-Dolastatin (1991) (1)
Bryostatin I Activates Protein Kinase C and Induces Monocytic Differentiation of HL-60 Cells (2005) (1)
Steroids and related natural products—XVII (1962) (1)
Structure of abnormal products isolated from the isomerization of 7-methoxychromano3,4-disoxazole - A novel synthesis of one of the products (1970) (1)
Hydrogenolysis of steroid 3β-acetoxy-5-ene systems (1970) (1)
Preparation of New Anti-Tubulin Ligands Through a Dual-Mode, Addition—Elimination Reaction to a Bromo-Substituted α,β-Unsaturated Sulfoxide. (2001) (1)
Steroids and related natural products. Part XLI. 14α-Methyl oestranes (1967) (1)
Correction. The isolation and structure elucidation of debromoaxinohydantoin (1995) (1)
Higher Plant Lignans (1977) (1)
N-alkyne-N-bis(2-chloroethyl)amines (1968) (1)
Antiviral (RNA) evaluation of a series of substituted tyrosines (1991) (1)
Cell growth inhibitory glycosides from Asclepias amplexicaulis. (1985) (1)
Antineoplastic Agents. Part 225. Isolation and Structure of Bryostatins 14 and 15. (1991) (1)
Cholestanes containing an oxygenated 14α-methyl group (1966) (1)
Marine Invertebrate and Other Lower Animal Biosynthetic Products (1977) (1)
SEPARATION OF THE BRYOSTATIN DERIVATIVES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (2000) (1)
Steroids and related natural products. Part XCI. Synthesis of the cardenolides canarigenin and uzarigenin. (1975) (1)
Arylmagnesium bromide additions to 1-tetralone-2-acetic acid followed by catalytic hydrogenolysis : stereochemical consequences (1991) (1)
Synthesis of marinobufagin and marinobufotoxin from telecinobufagin (1972) (1)
Antineoplastic Agent. Part 174. Isolation and Structure of the Cytostatic Depsipeptide Dolastatin 13 from the Sea Hare Dolabella auricularia. (1989) (1)
Correction - Formylation of Aromatic Amines with Dimethylformamide (1959) (1)
Notes: 2-Nitro-6-methoxybenzaldehyde (1959) (1)
BUFADIENOLIDES PART 25, DIRECT CONVERSION OF 14-DEHYDROBUFALIN TO BUFALIN (1973) (1)
850. Steroids and related natural products. Part XVIII. Synthesis of 14α-methylprogesterone (1963) (1)
Steroids and related natural products. Part XCII. Conversion of canarigenone[14-hydroxy-3-oxo-14β-carda-4,20(22)-dienolide] into periplogenin [3β,5,14-trihydroxy-5β,14β-card-20(22)-enolide] (1975) (1)
Optimization of Solvent Mixture Compositions for High Speed Countercurrent Distribution (1991) (1)
Antineoplastic agents, 195. Isolation and structure of aceratioside from Aceratium megalospermum. (1990) (1)
Steroids and related natural products. XLII. 14-alpha-methyl cholestanes. (1967) (1)
Antineoplastic Agents. Part 370. Isolation and Structure of Dolastatin 18. (1997) (1)
Steroids and related natural products. 97. The structure of 3β,16β,23(R),26-tetrahydroxy-5β-cholestane (1980) (1)
ANTINEOPLASTIC AGENTS: XVII. N-(2-BROMOETHYL)-N-(2-CHLOROETHYL)AMINES (1966) (1)
Isolation and Structure of the Cancer Cell Crowth Inhibitor Dictyostatin 1. (1994) (1)
Bufadienolides. 9. Isobufalin. (1970) (1)
Bufadienolides. 2. 20-hydroxy-21-nor-5-alpha-cholanic acid gamma-lactones (24--20). (1970) (1)
Antineoplastic Agents. Part 282. Isolation and Structure of the Remarkable Human Cancer Cell Growth Inhibitors Spongistatins 2 (Ia) and 3 (Ib) from an Eastern Indian Ocean Spongia sp. (1993) (1)
6,7-DIMETHOXYCARBOSTYRIL (1971) (1)
Oxidation of 3-beta-acetoxy-14-alpha-methyl-5-alpha-cholest-7-ene. (1968) (1)
Antineoplastic Agents. Part 247. The Dolastatins. Part 18. Isolation of Dolastatins 10‐15 from the Marine Mollusc Dolabella auricularia. (1994) (1)
Antimicrobial and cancer cell growth inhibitory activities of 3beta-acetoxy-17beta-(L-prolyl)amino-5alpha-androstane in vitro. (2000) (1)
Application of displacement thin-layer chromatography to toad-poison bufadienolides (1999) (1)
The dolastatins 25. Conformational isomerism of N-benzyloxycarbonl-N-methylisoleucinol and related substances (1995) (1)
STEROIDS AND RELATED NATURAL PRODUCTS. PART 95. BUFADIENOLIDES. PART 31. RESIBUFOGENIN STEREOISOMERS (1977) (1)
Antineoplastic Agents. Part 508. Synthesis and X-Ray Crystal Structure of the Dolabella auricularia Peptide Dolastatin 18. (2004) (1)
Presence of oncornavirus-like particles in the P388 murine leukemic cell line (1978) (1)
Synthesis of N-Methylene-N,N-Bis(2-Chloroethyl) Ammonium Hexachlorostannate (1981) (1)
Antineoplastic Agents. Part 390. Isolation and Structure of Phakellistatin 12 from a Chuuk Archipelago Marine Sponge. (2003) (1)
Antineoplastic Agents. Part 168. Isolation and Structure of Axinohydantoin (1991) (1)
Naturally Occurring Antineoplastic and Cytotoxic Agents (1977) (0)
Bryostatins: potent, new activators of protein kinase C (1986) (0)
Antineoplastic Agents. Part 248. Dolastatins. Part 20. A Convenient Synthetic Route to Dolastatin 15 (1995) (0)
BUFADIENOLIDE 7. MITT. SYNTH. VON 3BETA-ACETOXY-5ALPHA,14ALPHA-BUFA-20,20-DIENOLIDEN (1970) (0)
Synthesis and Biological Evaluation of a Spongistatin AB‐Spiroketal Analogue. (2002) (0)
Dolastatin 10 derivative (1993) (0)
Dolastatins and Antineoplastic Agents. Part 16. Dolastatins. Part 17. Synthesis of Dolaproine and Related Diastereoisomers. (1995) (0)
Antineoplastic Agents. Part 306. Isolation and Crystal Structure of Stylopeptide 1, a New Marine Porifera Cycloheptapeptide. (1996) (0)
Antineoplastic Agents. Part 110. Structural Biochemistry. Part 25. Synthesis of the Dolastatin 3 Isomer cyclo-(L-Pro-L-Leu-L-Val-(R,S)-(gln)-Thz-(gly)Thz). (1987) (0)
tetrapeptide tumor inhibitor which includes in its structure modified phenethylamides. (1993) (0)
STEROIDS AND RELATED NATURAL PRODUCTS XXVI. SYNTHESIS OF 3β-ACETOXY-20-OXO-5β-PREGNA-14,16-DIENE (1966) (0)
CRYSTAL AND MOLECULAR STRUCTURE OF THE UNUSUAL SPIRO DIHYDROFURAN DITERPENE NEPETAEFOLIN (1976) (0)
Isolation and Structure of Convolutamydines B (Ia), C (Ib), and D (Ic) from Marine Bryozoan Amathia convoluta. (1995) (0)
The structure of phyllanthose hexaacetate, C24H34O15 (1985) (0)
Chapter 9 – Octapeptides (1975) (0)
ANTINEOPLASTIC AGENTS. 70. SYNTHESIS OF N-METHYLENE-N,N-BIS(2-CHLOROETHYL)AMMONIUM HEXACHLOROSTANNATE (1981) (0)
Macrocyclic lactones inhibiting cell growth denominated combretastatin D-2. (1990) (0)
BUFADIENOLIDE 2. MITT. 20-HYDROXY-21-NOR-5ALPHA-CHOLANSAEURE-GAMMA-LACTONE (24-20) (1970) (0)
Direct photoaffinity labeling of tubulin by [H-3]dolastatin (1999) (0)
STEROIDS AND RELATED NATURAL PRODUCTS PART 91, SYNTHESIS OF THE CARDENOLIDES CANARIGENIN AND UZARIGENIN (1975) (0)
Steroids and Related Natural Products. Part 104. Bufadienolides. Part 36. Synthesis of Bufalitoxin (Ia) and Bufotoxin (Ib). (1988) (0)
Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide. (2000) (0)
Potentiation of the Activity of l-ÃŸ-o-Arabinofuranosylcytosine by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells: Association with Enhanced Fragmentation of Mature DNA1 (2006) (0)
Introduction and Perspective (1977) (0)
Antineoplastic Agents. Part 150. The Structure and Synthesis of Dolastatin 3. (1988) (0)
ANTINEOPLASTIC AGENTS PART 34, MELENIUM AUTUMNALE L. (1975) (0)
Bryostatin 1 in Primary Mouse Epidermal Cells by Phorbol 12 , 13-Dibutyrate Contrasting Duration of Inhibition of Cell-Cell Communication (2006) (0)
STEROIDS AND RELATED NATURAL PRODUCTS XXIX. SODIUM BOROHYDRIDE – BORON TRIHALIDE REDUCTION OF 3-OXO-4-OXA-5α-CHOLESTANE (1966) (0)
A beta-carboline-1-one mimic of the anticancer Amaryllidaceae constituent pancratistatin: synthesis and biological evaluation. (2004) (0)
Marine Animal and Terrestral Plant Anticancer Constituents. (1995) (0)
ANTINEOPLASTIC AGENTS. 68. SYNTHESIS OF A SPIROVETIVANE SYNTHON (1981) (0)
BUFADIENOLIDES PART 30, SYNTHESIS OF THE CH′AN SU COMPONENT 15BETA-HYDROXYBUFALIN (1975) (0)
Steroids. Part 347. Synthesis and in vitro Antimetabolic Evaluation of Some Steroidal Thiazoles. (1990) (0)
Synthesis of dolastatin 10 (2006) (0)
Cell growth inhibiting macrocyclic lactones called combretastatin D-2. (1990) (0)
Chapter 5 – Tetrapeptides (1975) (0)
Structures of 3β-hydroxy-5β-bufa-14,20,22-trienolide, C24H32O3, and 3β-acetoxy-15α-(o-nitrobenzoyloxy)-7-oxo-5β,14β-bufa-8,20,22-trienolide, C33H35NO9 (1983) (0)
Chapter 7 – Hexapeptides (1975) (0)
Bufadienolides. 23. 14,15 -Epoxy-3 ,11 -dihydroxy-5 -bufa-20,22-dienolide (11 -hydroxyresibufogenin). (1973) (0)
Corrigendum to "The interaction of spongistatin 1 with tubulin" [Arch. Biochem. Biophys. 727 (2022) 109296 (7 pages)]. (2022) (0)
ISOLATION AND X-RAY CRYSTAL STIIUCTUEE OF IULCEMIC IESTOSPONGIN D FROM THE sINGAPORE MALINE SPONGE NIPHATES SP x (1996) (0)
Thin-layer chromatography of bryostatins (1999) (0)
REDUCTION OF THE STEROIDAL SAPOGENIN SPIRO KETAL SYSTEM (1973) (0)
Marine Vertebrate and Other Higher Animal Biosynthetic Products (1977) (0)
Biosynthetic Products for Cancer Chemotherapy (1977) (0)
TheMarineProductCephalostatin1ActivatesanEndoplasmic ReticulumStress-specificandApoptosome-independent ApoptoticSignalingPathway * (2006) (0)
STEROIDS AND RELATED NATURAL PRODUCTS. XXV PHOTOCHEMICAL TRANSFORMATION OF 3β-NITRITO-5α-LANOSTANE (1965) (0)
Antineoplastic Agents. Part 228. Isolation and Structure of Cribrostatins 1 (I) and 2 (II) from the Blue Marine Sponge Cribrochalina sp. (1992) (0)
ANTINEOPLASTIC AGENTS. 66. STABILITY OF THE 1,4-BIS(2′-HALOETHYL)-1,4-DIAZABICYCLO(2.2.1)HEPTANE DICATION (1981) (0)
Higher Plant Alkaloids, Amides, and Ansa Macrolides (1977) (0)
Axastatin A, an antitumor agent from the marine sponge Axanilla sp. (1987) (0)
Peptides inhibiteurs du cancer (1995) (0)
Chapter 11 – Decapeptides (1975) (0)
Structural biochemistry XIII: Synthesis of luteinizing hormone-releasing hormone modification [Trp8]-LH-RH. (1979) (0)
Solid Phase Synthesis (1975) (0)
BUFADIENOLIDES PART 28, MARINOBUFOTOXIN (1975) (0)
Quinones, Flavans, and Other Nonnitrogenous Higher Plant Products (1977) (0)
Phyllanthostatin 1-Phyllanthoside Orthoacid Rearrangement. (1986) (0)
Peptides anti-cryptococcus (1999) (0)
Antineoplastic Agents. Part 267. The Dolastatins. Part 19. Synthesis of Dolaisoleucine. (1994) (0)
STEROIDS AND RELATED NATURAL PRODUCTS. 94. SYNTHESIS OF TOAD VENOM CARDENOLIDES (1977) (0)
Chapter 6 – Pentapeptides (1975) (0)
Steroids and related natural products. 93. Bufadienolides. 30. Synthesis of the Ch'an Su component 15.beta.-hydroxybufalin (1975) (0)
STRUCTURAL BIOCHEMISTRY. 14. PERMETHYLATION OF NUCLEOSIDES (1978) (0)
Epidermal Cells Effects of Phorbol Ester Tumor Promoters on Primary Mouse Partial Parallelism and Partial Blockade by Bryostatin 1 of Updated (2006) (0)
The cell growth inhibiting substance, process for their production, their use and pharmaceutical compositions containing them (1988) (0)
Antineoplastic agents. 18. N-(2-haloethyl)benzylamines. (1967) (0)
Fungi and Other Lower Plant Biosynthetic Products (1977) (0)
Association with Enhanced Fragmentation of Mature DNA by the Protein Kinase C Activator Bryostatin 1 in HL-60 Cells :d-Arabinofuranosylcytosine β Potentiation of the Activity of 1-Updated (2006) (0)
Erratum: Steroids and related natural products. VI. The structure of α-apoallobetulin (Journal of Organic Chemistry (1961) 26, (2879)) (1961) (0)
STEROIDS AND RELATED NATURAL PRODUCTS: XXXI. SELECTIVE REDUCTION OF ESTERS. PART B. CARBONATES (1966) (0)
Combretastatin A1 phosphate prodrugs and combretastatin B1 phosphate (2001) (0)
Erratum: The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway. (Journal of Biological Chemistry (2006) 281, (33078-33086)) (2006) (0)
In vitro interactions of approved and experimental drugs against Candida drugs against Candida spp. (2008) (0)
Chapter 16 – Cyclopeptides (1975) (0)
STRUCTURAL BIOCHEMISTRY. 19. SELECTIVE METHYLATION OF NUCLEOSIDES (1980) (0)
Structural biochemistry. 8. 9-Amino-(9-deoxy)-cinchona alkaloids. (1968) (0)
Peptides of 20 to 188 Units (1975) (0)
Steroids and Related Natural Products. Part 108. Bufadienolides. Part 40. Synthesis of the 14α- and 16α-Epimers of Bufotalin Acetate and 16-Deacetylcinobufagin. (1988) (0)
Structural biochemisry. XII. Synthesis of tobacco mosaic virus protein unit 150-158. (1973) (0)
Chapter 1 – Racemization (1975) (0)
Inhibitory substance of cellular development dite dolastatin 10 (1988) (0)
Erratum: Isolation and structure of stylostatin 1 from the papua New Guinea marine sponge Stylotella sp. (Journal of Organic Chemistry (1992) 57 (7217)) (1993) (0)
Duration of Exposure to 1 OOnM TPA ( hr ) : 0 1 2 4 8 24 48 72 SpiB ulated (2002) (0)
The camptothecin -lectone. (1972) (0)
Inhibit peptide amides human cancer (1995) (0)
Analysis of the Toad Poison Bufadienolides by Rod-Thin-Layer Chromatography with Flame Ionization Detector (2000) (0)
Antineoplastic Agents. Part 343. Synthesis of the Cyclic Heptapeptides Axinastatin 2 and Axinastatin 3 (1997) (0)
Steroids and Related Natural Products. Part 107. Bufadienolides. Part 39. Synthesis of 5α-Cinobufagin. (1987) (0)
BUFADIENOLIDES PART 26, SYNTHESIS OF SCILLARENIN (1974) (0)
Hydrogenolysis of the benzyl-oxygen bond by boron trifluoride-sodium borohydride (1962) (0)
Isolation and Structure of Halistatin 3 from the Western Pacific ( Chuuk) Marine Sponge Phakellia sp. (1995) (0)
Antineoplastic Agents. Part 160. Isolation and Structure of Combretastatin D-1 (I): A Cell Growth Inhibitory Macrocyclic Lactone from Combretum caffrum (1989) (0)
Structure of the Cornubert ketone (1982) (0)
Antineoplastic Agents. Part 111. Structural Biochemistry. Part 26. Synthesis of the Modified Dolastatin 3 Sequence cyclo-(L-Val-L-Leu-L-Pro- (R,S)-(gln)Thz-(gly)Thz). (1987) (0)
STRUCTURAL BIOCHEMISTRY. 17. SYNTHESIS OF TRYPTOPHAN DIPEPTIDES (1979) (0)
Isolation and structure of combretastatinl (1982) (0)
Antineoplastic Agents. Part 575. The Fungus Aspergillus phoenicis (2009) (0)
Chapter 3 – Dipeptides (1975) (0)
Antineoplastic Agents 397: Isolation and Structure of Sesterstatins 4 (Ia) and 5 (Ib) from Hyrtios erecta (the Republic of Maldives). (1998) (0)
STEROIDS AND RELATED NATURAL PRODUCTS PART 88, SYNTHESIS OF PERIPLOGENIN (1974) (0)
In Vitro Interactions of Approved and Experimental Drugs against Candida albicans and Aspergillus spp. (2008) (0)
BUFADIENOLIDE 23. MITT. 14,15BETA-EPOXY-3BETA,11ALPHA-DIHYDROXY-5BETA-BUFA-20,22-DIENOLID (11ALPHA-HYDROXY-RESIBUFOGENIN) (1973) (0)
Antineoplastic Agents. Part 287. The Dolastatins. Part 22. Synthesis of Boc‐dolaproinyl‐dolaphenine and Four Related Chiral Isomers. (1994) (0)
Chapter 8 – Heptapeptides (1975) (0)
1,4-BIS-BETA-CHLORAETHYL-1,4-DIAZA-BICYCLO(2,2,1)HEPTAN-DI-PERCHLORAT (1970) (0)
From a sea hare to global clinics (2012) (0)
Synthesis and in vitro Cancer Cell Growth Inhibitory Activity of Monocyclic Model Compounds Containing Spongistatin Triene Side‐Chains. (1998) (0)
Correction. Synthesis of the Streptomyces ambofaciens Antineoplastic Constituent 6-Diazo-5-oxo-L-norleucine (1983) (0)
Successful treatment of chronic lymphocytic leukemia (CLL) xenografts with marine animal products (1997) (0)
[Mass spectrum studies of natural products; cardenolides]. (1972) (0)
Antineoplastic Agents. Part 136. The Isolation and Structure of a Remarkable Marine Animal Antineoplastic Constituent: Dolastatin 10 (1988) (0)
The crystal structure of 3 beta-hydroxy-4 alpha, 23R, 24R-trimethyl-5 alpha-cholestane (23R, 24R-5 alpha-dinostanol) from dinoflagellates. (1986) (0)
Tetrapeptides portants des phenethylamides modifiés comme inhibiteurs de tumeurs (1993) (0)
BUFADIENOLIDES PART 19, 3BETA-ACETOXY-15-OXO-5BETA,14BETA-BUFA-8,20,22-TRIENOLIDE (1975) (0)
Rearrangement of isodigitoxigenin (1967) (0)
Undecapeptides to Nonadecapeptides (1975) (0)
Steroids and related natural products. Part XCII. Conversion of canarigenone (14-hydroxy-3-oxo-14beta-carda-4,20(22)-dienolide) into periplogenin (3beta,5,14-trihydroxy-5beta,14beta-card-20(22)-enolide). (1975) (0)
Antineoplastic Agents. Part 378. Isolation and Structure of Spongilipid from the Republic of Singapore Marine Porifera Spongia cf. hispida. (1997) (0)
ANTINEOPLASTIC AGENTS PART 36, ACETYLENIC CARRIER GROUPS (1974) (0)
Erratum: Synthesis of the Streptomyces ambofaciens antineoplastic constituent 6-diazo-5-oxo-L-norleucine (Journal of Organic Chemistry (1983) 48 (741)) (1983) (0)
Chapter 19 – Chromopeptides (1975) (0)
The structure of phyllanthocindiol methyl ester, C25H32O8 (1984) (0)
Bufadienolides. 7. Synthesis of 3-beta-acetoxy-5-alpha,14-alpha-bufa-20,22-dienolide. (1970) (0)
Chapter 10 – Nonapeptides (1975) (0)
Antineoplastic Agents. Part 193. Isolation and Structure of the Cyclic Peptide Hymenistatin 1 (1990) (0)
Antineoplastic Agents. Part 318. Dolastatins. Part 23. Stereospecific Synthesis of Dolaisoleuine. (1996) (0)
Higher Plant Steroids (1977) (0)
SYNTH. DER TABAK-MOSAIK-VIRUS-PROTEIN-SEQUENZ 81-85 (1971) (0)
Chapter 18 – Steroidal Peptides (1975) (0)
Depsipeptides and Cyclodepsipeptides (1975) (0)
Chapter 20 – Nucleopeptides (1975) (0)
STEROIDS AND RELATED NATURAL PRODUCTS PART 90, 15BETA-HYDROXYDIGITOXIGENIN (1975) (0)
BUFADIENOLIDES PART 17, SYNTHESIS OF 14ALPHA- UND 14BETA-ARTEBUFOGENIN (1973) (0)
(+)‐Phorboxazole A Synthetic Studies. Identification of a Series of Highly Cytotoxic C(45—46) Analogues. (2006) (0)
Isolation and structural elucidation of 3,6-dioxo-hexahydro-pyrrolo (1,2-a)-pyrazine from the echinoderm Luidia clathrata. (1973) (0)
Antineoplastic Agents. Part 119. Isolation and Structure of Bryostatins 10 and 11. (1988) (0)
Chapter 15 – Polypeptides (1975) (0)
SYNTH. DES BUFALINS (1970) (0)
ANTINEOPLASTIC AGENTS. LXIV: 1,4-BIS(2′-CHLOROETHYL)-1,4-DIAZABICYCLO(2.2.1)HEPTANE DIHYDROGEN DIMALEATE (1980) (0)
Antineoplastic phenanthridoner, pharmaceutical compositions containing them and to their use for the preparation of a pharmaceutical composition for treating a host, afflicted with a neoplastic disease (1985) (0)
BUFADIENOLIDES PART 29, SYNTHETIC ROUTES TO BUFOTALIN (1975) (0)
Antineoplastic Agents. Part 266. The Dolastatins. Part 18. Stereospecific Synthesis of Dolaproine. (1996) (0)
Tumor-inhibiting tetrapeptides with modified phenethylamide groups (1993) (0)
Bryostatins activate protein kinase C in intact human platelets (1986) (0)
Steroids and related natural products. XLI. 14 alpha-Methyl Oestranes. (1967) (0)
Dolastatins. Part 24. Synthesis of (‐)‐Dolastatin 10. X‐Ray Molecular Structure of N,N‐Dimethylvalyl‐valyl‐dolaisoleuine tert‐Butyl Ester. (1996) (0)
ANTINEOPLASTIC substance called rolliniastatine 1 (1988) (0)
Structure of abnormal products isolated from the isomerization of 7-methoxychromano3,4-disoxazole (1968) (0)
Antineoplastic Agents. Part 157. Quassia kerstingii. (1988) (0)
Chapter 4 – Tripeptides (1975) (0)
Synthesis of 3-beta-acetoxy-17-beta-(L-arginyl-L-arginyl-L-prolyl) amino-5-alpha-androstane. (1967) (0)
BUFADIENOLIDE 13. MITT. UMWANDLUNG VON 3BETA-HYDROXY-17-OXO-ANDROST-5-EN IN 3BETA-ACETOXY-5BETA,14ALPHA-BUFA-20,22-DIENOLID (1972) (0)
Antineoplastic Agents. Part 129. Cell Growth Inhibitory Dihydrophenanthrene and Phenanthrene Constituents of the African Tree Combretum caffrum. (1988) (0)
Antineoplastic Agents. Part 224. Isolation and Structure of Neristatin 1. (1991) (0)
Steroids and related natural products. 14α-Methyl testosterone (1963) (0)
STEROIDS AND RELATED NATURAL PRODUCTS. 96. SYNTHESIS OF 3β,16β,23(R),26‐TETRAHYDROXY‐5β‐CHOLESTANE (1979) (0)
Peptapeptid acid methyl esters which inhibit human cancer (1995) (0)
Antineoplastic Agents. Part 147. Isolation and Structure of the Powerful Cell Growth Inhibitor Cephalostatin 1 (1988) (0)
Synthetic Methods A b-Carboline-1-one Mimic of the Anticancer Amaryllidaceae Constituent Pancratistatin : Synthesis and Biological Evaluation * * (2004) (0)
Erratum: Formylation of aromatic amines with dimethylformamide (Journal of Organic Chemistry (1959) 24, (895)) (1959) (0)

This paper list is powered by the following services:

Other Resources About George R. Pettit

en.wikipedia.org

What Schools Are Affiliated With George R. Pettit?

George R. Pettit is affiliated with the following schools:

George R. Pettit's Academic­Influence.com Rankings