George Stamatoyannopoulos | Academic Influence

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George Stamatoyannopoulos

Biology

#4796

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#7107

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Genetics

#451

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#520

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Molecular Biology

#540

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#553

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Biology

George Stamatoyannopoulos's Degrees

Bachelors Biology University of Crete
PhD Genetics University of Crete

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Why Is George Stamatoyannopoulos Influential?

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According to Wikipedia, George Stamatoyannopoulos was a Greek geneticist who taught at the University of Washington. Born in Athens on 11 March 1934, Stamatoyannopoulos earned a medical degree and doctorate from the University of Athens. He began teaching at the University of Washington in 1964, and was appointed a full professor in 1973. Stamatoyannopoulos led the Division of Medical Genetics at UW from 1989 to 2005, succeeding the department's founder, Arno Motulsky, who had served since 1957. Stamatoyannopoulos served as president of the American Society of Hematology in 1992, and became the founding leader of the American Society of Gene and Cell Therapy in 1996, which he established because he felt that the American Society of Human Genetics did not fully discuss gene therapy. In 2004, he was made a fellow of the American Academy of Arts and Sciences.

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George Stamatoyannopoulos's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The accessible chromatin landscape of the human genome (2012) (2395)
The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
An integrated encyclopedia of DNA elements in the human genome (2012) (2080)
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations (2016) (1009)
The molecular basis of blood diseases (1987) (620)
Locus control regions. (2002) (454)
Control of globin gene expression during development and erythroid differentiation. (2005) (403)
Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. (1987) (374)
Efficient Gene Transfer into Human CD34+ Cells by a Retargeted Adenovirus Vector (2000) (364)
Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice (1990) (325)
Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease. (1999) (260)
F-cells in the adult: normal values and levels in individuals with hereditary and acquired elevations of Hb F. (1975) (257)
A chromatin insulator protects retrovirus vectors from chromosomal position effects. (2000) (253)
Hemoglobin switching (1978) (225)
Hemoglobin F synthesis in vitro: evidence for control at the level of primitive erythroid stem cells. (1977) (216)
Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. (2003) (212)
Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. (1993) (208)
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction. (2002) (203)
Triplicated alpha-globin loci in humans. (1980) (193)
Hemophilia A. Detection of molecular defects and of carriers by DNA analysis. (1985) (186)
MicroRNA expression dynamics during murine and human erythroid differentiation. (2007) (167)
G to A substitution in the distal CCAAT box of the Aγ-globin gene in Greek hereditary persistence of fetal haemoglobin (1985) (166)
Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity. (1975) (164)
Genetic origins of the Minoans and Mycenaeans (2017) (158)
Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea. (1985) (157)
Stimulation of fetal hemoglobin synthesis by erythropoietin in baboons. (1987) (155)
Neutrophil dysfunction, chronic granulomatous disease, and non-spherocytic haemolytic anaemia caused by complete deficiency of glucose-6-phosphate dehydrogenase. (1973) (153)
Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus. (1983) (148)
Autonomous developmental control of human embryonic globin gene switching in transgenic mice. (1990) (148)
Cellular and molecular regulation of hemoglobin switching (1979) (132)
GATA1 and YY1 are developmental repressors of the human epsilon‐globin gene. (1995) (127)
Functional footprinting of regulatory DNA (2015) (123)
On the induction of fetal hemoglobin by butyrates: in vivo and in vitro studies with sodium butyrate and comparison of combination treatments with 5-AzaC and AraC. (1989) (123)
Arabinosylcytosine induces fetal hemoglobin in baboons by perturbing erythroid cell differentiation kinetics. (1984) (122)
Types of Thalassaemia‐Trait Carriers as Revealed by a Study of their Incidence in Greece (1962) (122)
FKLF, a Novel Krüppel-Like Factor That Activates Human Embryonic and Fetal β-Like Globin Genes (1999) (120)
Fetal Hb Production during Acute Erythroid Expansion: I. OBSERVATIONS IN PATIENTS WITH TRANSIENT ERYTHROBLASTOPENIA AND POST‐PHLEBOTOMY (1980) (119)
Cellular regulation of hemoglobin switching: evidence for inverse relationship between fetal hemoglobin synthesis and degree of maturity of human erythroid cells. (1979) (114)
Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo. (2002) (114)
Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants. (1995) (113)
Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice. (1996) (109)
Hypersensitive site 5 of the human beta locus control region functions as a chromatin insulator. (1994) (109)
Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR. (2001) (109)
Stimulation of fetal hemoglobin synthesis in bone marrow cultures from adult individuals. (1976) (109)
Role of gene order in developmental control of human gamma- and beta-globin gene expression (1993) (106)
Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion (1998) (101)
HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN IN GREECE. A STUDY AND A COMPARISON. (1964) (100)
A new form of hereditary persistence of fetal hemoglobin in blacks and its association with sickle cell trait. (1975) (98)
Developmental regulation of human gamma-globin genes in transgenic mice (1993) (97)
FKLF-2: a novel Krüppel-like transcriptional factor that activates globin and other erythroid lineage genes. (2000) (93)
Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects. (2007) (91)
Engraftment of immune-deficient mice with primitive hematopoietic cells from beta-thalassemia and sickle cell anemia patients: implications for evaluating human gene therapy protocols. (1995) (91)
Genomic discovery of potent chromatin insulators for human gene therapy (2015) (90)
The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice. (1989) (84)
Regulation of embryonic/fetal globin genes by nuclear hormone receptors: a novel perspective on hemoglobin switching (1999) (83)
Functional Interaction between Coactivators CBP/p300, PCAF, and Transcription Factor FKLF2* (2002) (83)
Perspectives on ENCODE (2020) (79)
Butyrate increases the efficiency of translation of γ-globin mRNA (2005) (77)
Perturbations in the erythroid marrow progenitor cell pools may play a role in the augmentation of HbF by 5-azacytidine. (1984) (77)
Developmental regulation of human globin genes in transgenic mice. (1985) (76)
Transgenic mice expressing human fetal globin are protected from malaria by a novel mechanism. (1998) (75)
Hb F Production in Stressed Erythropoiesis: Observations and Kinetic Modelsa a (1985) (75)
Thalassaemia (2012) (75)
Induction of human γ globin gene expression by histone deacetylase inhibitors (2004) (75)
Erythroid progenitors circulating in the blood of adult individuals produce fetal hemoglobin in culture. (1978) (74)
Stimulation of fetal hemoglobin production by short chain fatty acids. (1995) (73)
Retroviral-mediated transfer of genomic globin genes leads to regulated production of RNA and protein. (1987) (72)
alpha-Amino-N-butyric acid stimulates fetal hemoglobin in the adult. (1988) (71)
Topological constraints governing the use of the chicken HS4 chromatin insulator in oncoretrovirus vectors. (2002) (70)
Analysis of human hemoglobin switching in MEL × human fetal erythroid cell hybrids (1986) (69)
Demonstration of a human epsilon-globin gene silencer with studies in transgenic mice. (1992) (66)
Genomic and functional assays demonstrate reduced gammaretroviral vector genotoxicity associated with use of the cHS4 chromatin insulator. (2009) (65)
Human hemoglobin switching. (1991) (65)
Fetal expression of a human Agamma globin transgene rescues globin chain imbalance but not hemolysis in EKLF null mouse embryos. (2000) (64)
Erythrocytosis associated with hemoglobin Rainier: oxygen equilibria and marrow regulation. (1969) (63)
Monoclonal antibodies specific for globin chains. (1983) (63)
Nature of fetal hemoglobin in the Greek type of hereditary persistence of fetal hemoglobin with and without concurrent beta-thalassemia. (1970) (62)
Maritime route of colonization of Europe (2014) (62)
Hematopoietic stem cell mobilization for gene therapy of adult patients with severe β-thalassemia: results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects. (2012) (62)
DNA methylation: a secondary event in globin gene switching? (1988) (62)
Beta-globin locus activation regions: conservation of organization, structure, and function. (1990) (60)
Hemoglobin "pylos": study of a hemoglobinopathy resembling thalassemia in the heterozygous, homozygous and double heterozygous state. (1962) (59)
A High-Capacity, Capsid-Modified Hybrid Adenovirus/Adeno-Associated Virus Vector for Stable Transduction of Human Hematopoietic Cells (2002) (59)
A capsid-modified adenovirus vector devoid of all viral genes: assessment of transduction and toxicity in human hematopoietic cells. (2001) (59)
HbF and HbA production in erythroid cultures from human fetuses and neonates. (1979) (58)
Simultaneous purification of DNA and RNA from small numbers of eukaryotic cells. (1989) (57)
Rapid increase in red blood cell density driven by K:Cl cotransport in a subset of sickle cell anemia reticulocytes and discocytes. (1991) (56)
Physiologic implications of a hemoglobin with decreased oxygen affinity (hemoglobin seattle). (1969) (55)
Abnormal hemoglobins with high and low oxygen affinity. (1971) (55)
Globin synthesis in fractionated Normoblasts of beta-thalassemia heterozygotes. (1975) (54)
Monoclonal antibodies detecting antigenic determinants with restricted expression on erythroid cells: from the erythroid committed progenitor level to the mature erythroblast. (1984) (53)
Fetal hemoglobin induction with butyric acid: efficacy and toxicity. (1993) (53)
On the familial predisposition to favism. (1966) (52)
Functional study of transcription factor KLF11 by targeted gene inactivation. (2005) (52)
alpha-Amino butyric acid cannot reactivate the silenced gamma gene of the beta locus YAC transgenic mouse. (1994) (52)
Hemoglobinopathic erythrocytosis due to a new electrophoretically silent variant, hemoglobin San Diego (beta109 (G11)val--met). (1974) (52)
Hematopoietic stem cell mobilization for gene therapy: superior mobilization by the combination of granulocyte-colony stimulating factor plus plerixafor in patients with β-thalassemia major. (2013) (51)
Role of NF-Y in In Vivo Regulation of the γ-Globin Gene (2001) (51)
Fetal hemoglobin in acute and chronic states of erythroid expansion. (1993) (51)
Genetic correction of sickle cell disease: Insights using transgenic mouse models (2000) (51)
Sequences Located 3′ to the Breakpoint of the Hereditary Persistence of Fetal Hemoglobin-3 Deletion Exhibit Enhancer Activity and Can Modify the Developmental Expression of the Human Fetal Aγ-Globin Gene in Transgenic Mice * (1995) (51)
Reactivation of γ-globin in adult β-YAC mice after ex vivo and in vivo hematopoietic stem cell genome editing. (2018) (50)
Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe (2018) (50)
Treatment of baboon with vinblastine: insights into the mechanisms of pharmacologic stimulation of Hb F in the adult. (1985) (50)
Functional interplay between CBP and PCAF in acetylation and regulation of transcription factor KLF13 activity. (2003) (49)
Butyrate increases the efficiency of translation of gamma-globin mRNA. (2005) (49)
Identification of Haemoglobin S in Red Cells and Normoblasts, Using Fluorescent Anti‐Hb S Antibodies (1976) (49)
Hemoglobins in human fetuses: evidence for adult hemoglobin production after the 11th gestational week. (1972) (49)
Alpha-thalassemia in two Mediterranean populations. (1982) (48)
Hemoglobin olympia ( 20 valine leads to methionine): an electrophoretically silent variant associated with high oxygen affinity and erythrocytosis. (1973) (48)
Genetic diversity of the "Mediterranean" glucose-6-phosphate dehydrogenase deficiency phenotype. (1971) (48)
Inclusion-Body β-Thalassemia Trait (1974) (48)
F-Thalassemia. A study of thirty-one families with simple heterozygotes and combinations of F-Thalassemia with A2-Thalassemia. (1969) (46)
Plerixafor+G-CSF-mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy. (2015) (46)
Histone acetylation at the human β-globin locus changes with developmental age (2004) (46)
F reticulocyte response in sickle cell anemia treated with recombinant human erythropoietin: a double-blind study. (1993) (46)
The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis. (2001) (45)
A European population in Minoan Bronze Age Crete (2013) (45)
Genetic influences on serum cholesterol in two Greek villages. (1969) (44)
The molecular basis of hemoglobin disease. (1972) (44)
Fetal gene reactivation. (1998) (44)
Genomic footprinting and sequencing of human beta-globin locus. Tissue specificity and cell line artifact. (1994) (44)
Induction of human gamma globin gene expression by histone deacetylase inhibitors. (2004) (44)
One form of inclusion body beta-thalassemia is due to a GAA----TAA mutation at codon 121 of the beta chain. (1989) (43)
LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs. (1998) (43)
X-linked syndrome of platelet dysfunction, thrombocytopenia, and imbalanced globin chain synthesis with hemolysis. (1977) (43)
Use of yeast artificial chromosomes (YASs) for studying control of gene expression: Correct regulation of the genes of a human β-globin locus YAC following transfer to mouse erythroleukemia cell lines (1993) (43)
Adenosine deaminase: racial distribution and report of a new phenotype. (1970) (43)
Fetal hemoglobin induction by acetate, a product of butyrate catabolism. (1994) (43)
Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea. (1988) (42)
Haemoglobin Rainier : β145 (HC2) Tyrosine→Cysteine and Haemoglobin Bethesda: β145 (HC2) Tyrosine → Histidine (1971) (42)
Adult haematopoietic cells transplanted to sheep fetuses continue to produce adult globins (1982) (42)
Activation of β-Globin Promoter by Erythroid Krüppel-Like Factor (1998) (41)
Coexpression of embryonic, fetal, and adult globins in erythroid cells of human embryos: relevance to the cell-lineage models of globin switching. (1987) (41)
Anti-HEL cell monoclonal antibodies recognize determinants that are also present in hemopoietic progenitors. (1984) (41)
F reticulocyte response in sickle cell anemia treated with recombinant human erythropoietin: a double-blind study (1993) (40)
Effects of interleukin-3 and erythropoietin on in vivo erythropoiesis and F-cell formation in primates. (1989) (40)
Development of Viral Vectors for Gene Therapy of β-Chain Hemoglobinopathies: Optimization of a γ-Globin Gene Expression Cassette (1999) (39)
Binary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expression. (1997) (39)
In vivo search for butyrate responsive sequences using transgenic mice carrying A gamma gene promoter mutants. (1996) (39)
Thalassaemia, Glucose-6-Phosphate Dehydrogenase Deficiency, Sickling, and Malarial Endemicity in Greece: A Study of Five Areas* (1964) (39)
Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice. (2002) (39)
Globin Gene Switching (1996) (39)
Chinese A gamma fetal hemoglobin: C to T substitution at position-196 of the A gamma gene promoter. (1986) (38)
Chromatin structure and developmental expression of the human alpha-globin cluster (1986) (38)
Hematopoietic Stem Cell Gene Therapy (2002) (38)
Substitution of the Human β-Spectrin Promoter for the Human Aγ-Globin Promoter Prevents Silencing of a Linked Human β-Globin Gene in Transgenic Mice (1998) (38)
Stochastic expression of fetal hemoglobin in adult erythroid cells. (1981) (38)
Frequencies of Thalassemia in American Blacks (1977) (37)
Thalassemias, Abnormal Hemoglobins and Glucose‐6‐Phosphate Dehydrogenase Deficiency in the Arta Area of Greece: Diagnostic and Genetic Aspects of Complete Village Studies * (1964) (37)
Thalassaemia in Cyprus (1973) (37)
Systematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiation. (2007) (36)
Hemoglobin Rainier (β145 Tyrosine → Histidine): Alkali-Resistant Hemoglobin with Increased Oxygen Affinity (1968) (36)
Molecular basis of hemoglobin-H disease in the Mediterranean population (1979) (36)
Stem cell gene therapy, position effects and chromatin insulators (1997) (36)
Developmental specificity of recruitment of TBP to the TATA box of the human γ-globin gene (2002) (36)
Hemoglobin switching in culture: evidence for a humoral factor that induces switching in adult and neonatal but not fetal erythroid cells. (1982) (36)
Globin Chain Synthesis in the Greek Type (Aγ) of Hereditary Persistence of Fetal Haemoglobin (1975) (35)
Adeno-associated virus 2-mediated transduction and erythroid cell-specific expression of a human beta-globin gene. (1996) (35)
Transcriptional activation of human zeta 2 globin promoter by the alpha globin regulatory element (HS-40): functional role of specific nuclear factor-DNA complexes (1993) (35)
Cooperative enhancement of F-cell formation in baboons treated with erythropoietin and hydroxyurea (1988) (35)
Hemoglobin Köln disease occurring as a fresh mutation: erythrocyte metabolism and survival. (1971) (35)
Cellular distribution of hemoglobin F in a clonal hemopoietic stem-cell disorder. (1978) (33)
Carbohydrate antigen profiles of human erythroleukemia cell lines HEL and K562. (1983) (33)
Developmentally Specific Role of the CCAAT Box in Regulation of Human γ-Globin Gene Expression* (2004) (33)
Cooperativeness of the higher chromatin structure of the beta-globin locus revealed by the deletion mutations of DNase I hypersensitive site 3 of the LCR. (2007) (33)
Developmental programs of human erythroleukemia cells: globin gene expression and methylation (1988) (33)
Sheep fetal haematopoietic cells produce adult haemoglobin when transplanted in the adult animal (1979) (32)
Genetic studies on southeastern Bantu of Mozambique. I. Variants of glucose-6-phosphate dehydrogenase. (1970) (32)
Absence of Hæmoglobin A2 in an Adult (1962) (32)
Histone acetylation at the human beta-globin locus changes with developmental age. (2007) (32)
Correct function of the locus control region may require passage through a nonerythroid cellular environment. (1999) (32)
Pitfalls of genetic testing. (1996) (31)
Use of specific fluorescent antibodies for the identification of hemoglobin C in erythrocytes (1977) (31)
Influence of recombinant hematopoietins and of fetal bovine serum on the globin synthetic pattern of human BFUe. (1990) (31)
Stem Cell Gene Therapy for the β‐Chain Hemoglobinopathies: Problems and Progress a (1999) (31)
Characterization of a novel form of transferrin receptor preferentially expressed on normal erythroid progenitors and precursors. (1989) (31)
SERUM-CHOLESTEROL AND THALASSÆMIA TRAIT (1963) (31)
Analysis of gamma-globin expression cassettes in retrovirus vectors. (1999) (30)
Fetal calf serum contains activities that induce fetal hemoglobin in adult erythroid cell cultures. (1990) (30)
Simultaneous assessment of i-antigenic expression and fetal hemoglobin in single red cells by immunofluorescence. (1980) (30)
Recessive familial erythrocytosis: aspects of marrow regulation in two families. (1973) (30)
The Kenya Form of Hereditary Persistence of Fetal Haemoglobin: Structural Studies and Evidence for Homogeneous Distribution of Haemoglobin F using Fluorescent Anti‐haemoglobin F Antibodies (1976) (29)
Synergistic and Additive Properties of the Beta-Globin Locus Control Region (LCR) Revealed by 5′HS3 Deletion Mutations: Implication for LCR Chromatin Architecture (2005) (29)
Development of a somatic mutation screening system using Hb mutants. IV. Successful detection of red cells containing the human frameshift mutants Hb Wayne and Hb Cranston using monospecific fluorescent antibodies. (1980) (29)
Structural analysis and mapping of DNase I hypersensitivity of HS5 of the beta-globin locus control region. (1999) (29)
SFL 23.6: a monoclonal antibody reactive with CFU-E, erythroblasts, and erythrocytes. (1985) (29)
Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells. (1995) (29)
Detection of glucose-6-phosphate dehydrogenase deficient heterozygotes. (1967) (29)
Clinical implications of glucose-6-phosphate dehydrogenase deficiency. (1966) (28)
Consistent activation of fetal hemoglobin synthesis in cultured adult bone marrow cells. (1978) (27)
Three inherited red-cell abnormalities in a district of Greece. Thalassaemia, sickling, and glucose-6-phosphate-dehydrogenase deficiency. (1963) (27)
PSEUDO-MOSAICISM IN MALES WITH MILD GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY. (1964) (27)
Comparison of expression of human globin genes transferred into mouse erythroleukemia cells and in transgenic mice. (1998) (27)
OBSERVATIONS ON HEMOGLOBIN "PYLOS": THE HEMOGLOBIN PYLOS-HEMOGLOBIN S COMBINATION. (1963) (26)
Glucose‐6‐phosphate dehydrogenase, colour vision and Xg blood groups in Greece: linkage and population data (1963) (26)
Locus control region-A gamma transgenic mice: a new model for studying the induction of fetal hemoglobin in the adult. (1991) (26)
Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene. (2002) (26)
Cell sorter immunofluorescence detection of human erythrocytes labelled in suspension with antibodies specific for hemoglobin S and C. (1981) (26)
Effects of butyrate and glucocorticoids on gamma- to beta-globin gene switching in somatic cell hybrids (1995) (26)
MILD GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY IN GREEK MALES. (1964) (26)
Developmental regulation of fetal to adult globin gene switching in human fetal erythroid x mouse erythroleukemia cell hybrids. (1991) (25)
Genome Architecture of the Human β-Globin Locus Affects Developmental Regulation of Gene Expression (2005) (25)
BIOCHEMICAL GENETICS OF GLUCOSE‐6‐PHOSPHATE DEHYDROGENASE VARIATION * (1968) (25)
Gene therapy for β-thalassaemia: the continuing challenge (2010) (25)
The distribution of glucose-6-phosphate dehydrogenase deficiency in Greece. (1966) (25)
Hemoglobins in development and differentiation (1981) (25)
Analysis of the mechanism of action of non‐deletion hereditary persistence of fetal hemoglobin mutants in transgenic mice (2001) (25)
Hb F production of endogenous colonies of polycythemia vera. (1979) (25)
Comprehensive characterization of erythroid-specific enhancers in the genomic regions of human Krüppel-like factors (2013) (25)
Asynchronous synthesis of HbF and HbA during erythroblast maturation. II. Studies of G gamma, A gamma, and beta chain synthesis in individual erythroid clones from neonatal and adult BFU-E cultures (1981) (24)
Athens Variant of Glucose-6-Phosphate Dehydrogenase (1967) (24)
Development of a Condensed Locus Control Region Cassette and Testing in Retrovirus Vectors forAγ-Globin (1998) (24)
Fetal hemoglobin synthesis in vivo: direct evidence for control at the level of erythroid progenitors. (1988) (24)
Hydroxamide derivatives of short-chain fatty acids are potent inducers of human fetal globin gene expression. (2003) (24)
Activation of developmentally mutated human globin genes by cell fusion. (1988) (23)
Novel in vitro assay for the detection of pharmacologic inducers of fetal hemoglobin (2000) (23)
Multiple ε-Promoter Elements Participate in the Developmental Control of ε-Globin Genes in Transgenic Mice* (1998) (23)
Hypersensitive site 5 of the human beta locus control region functions as a chromatin insulator (1994) (23)
Greek (Aγ) variant of hereditary persistence of fetal haemoglobin: globin gene organization and studies of expression of fetal haemoglobins in clonal erythroid cultures (1982) (22)
The G and A hemoglobin chains during human fetal development. (1973) (22)
Analysis of the human zeta-globin gene promoter in transgenic mice. (1993) (22)
Structurally diverse molecular deletions in the beta-globin gene cluster exhibit an identical phenotype on interaction with the beta S-gene. (1985) (22)
Transgenic mice containing a 248-kilobase human beta locus yeast artificial chromosome display proper developmental control of human globin genes. (1993) (22)
Hydroxamide derivatives of short-chain fatty acid have erythropoietic activity and induce gamma gene expression in vivo. (2005) (22)
Neuropathology of Cyanate Toxicity in Rhesus Monkeys (1974) (21)
Stochastic branching model for hemopoietic progenitor cell differentiation (1985) (21)
Histone deacetylase inhibitor FK228 is a potent inducer of human fetal hemoglobin (2006) (21)
Cooperative enhancement of F-cell formation in baboons treated with erythropoietin and hydroxyurea. (1988) (21)
Evidence for Duplication of the Haemoglobin γ Chain Locus in Macaca nemestrina (1971) (21)
Analysis of enhancer function of the HS-40 core sequence of the human alpha-globin cluster. (1997) (21)
Laotian (delta beta) (0)-thalassemia: molecular characterization of a novel deletion associated with increased production of fetal hemoglobin. (1988) (21)
Locus control region-A gamma transgenic mice: a new model for studying the induction of fetal hemoglobin in the adult (1991) (20)
Activation of the β-like globin genes in transgenic mice is dependent on the presence of the β-locus control region (2002) (20)
Inclusion-body beta-thalassemia trait. A form of beta thalassemia producing clinical manifestations in simple heterozygotes. (1974) (20)
Mapping of a syndrome of X-linked thrombocytopenia with thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia (2000) (20)
Transgenic mouse model of pharmacologic induction of fetal hemoglobin: Studies using a new ribonucleotide reductase inhibitor, didox (1994) (20)
Erythropoietin stimulates F-reticulocyte formation in sickle cell anemia. (1988) (20)
Activation of Hemoglobin C Synthesis in Sheep Marrow Culture (1973) (20)
Molecular abnormalities of a human glucose-6-phosphate dehydrogenase variant associated with undetectable enzyme activity and immunologically cross-reacting material. (1992) (19)
Activation of beta-globin promoter by erythroid Krüppel-like factor. (1998) (19)
Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease (2010) (19)
Gene frequencies at loci determining blood-group and serum-protein polymorphisms in two villages of northwestern Greece. (1969) (19)
Developmentally specific role of the CCAAT box in regulation of human gamma-globin gene expression. (2004) (19)
Only adult hemoglobin is produced in fetal nonerythroid x MEL cell hybrids. (1986) (19)
Identification of a major positive regulatory element located 5' to the human zeta-globin gene. (1995) (19)
Primary structure of the goat β-globin locus control region (1991) (19)
MAPPING OF ANTIGENIC SITES ON HUMAN HAEMOGLOBIN BY MEANS OF MONOCLONAL ANTIBODIES AND HAEMOGLOBIN VARIANTS (1981) (19)
Fetal to adult hemopoietic cell transplantation in humans: insights into hemoglobin switching. (1986) (19)
Fetal hemoglobin in paroxysmal nocturnal hemoglobinuria (PNH): evidence for derivation of HbF-containing erythrocytes (F cells) from the PNH clone as well as from normal hemopoietic stem cell lines. (1978) (18)
Production of transgenic mice with yeast artificial chromosomes. (1997) (18)
Direct evidence for interaction between human erythroid progenitor cells and a hemoglobin switching activity present in fetal sheep serum. (1983) (18)
Novel in vitro assay for the detection of pharmacologic inducers of fetal hemoglobin. (2000) (18)
The mechanism of expansion of late erythroid progenitors during erythroid regeneration: target cells and effects of erythropoietin and interleukin-3. (1989) (18)
Concordance of a point mutation 5' to the A gamma-globin gene with A gamma beta + hereditary persistence of fetal hemoglobin in Greeks. (1986) (18)
Fetal hemoglobin in polycythemia vera: cellular distribution in 50 unselected patients. (1979) (18)
Molecular basis of hemoglobin-H disease in the Mediterranean population. (1979) (17)
THE BETA‐DELTA THALASSEMIAS s1 (1969) (17)
The asynchrony of γ- and β-chain synthesis during human erythroid cell maturation: III. γ- and β-mRNA in immature and mature erythroid clones (1981) (17)
Acceleration of F‐cell production in response to experimentally induced anemia in adult baboons (Papio cynocephalus) (1980) (17)
Role of NF-Y in in vivo regulation of the gamma-globin gene. (2001) (17)
β‐YAC Transgenic Mice for Studying LCR Function a (1998) (17)
Transgenic Cre expression mice for generation of erythroid‐specific gene alterations (2004) (17)
Role of penultimate tyrosine in haemoglobin subunit. (1972) (16)
Hemoglobin switching and its clinical implications. (1994) (16)
The position of integration affects expression of the A gamma-globin-encoding gene linked to HS3 in transgenic mice. (1995) (16)
Studies of Hb F in adult nonanemic baboons: Hb F expression in erythroid colonies decreases as the level of maturation of erythroid progenitors advances. (1985) (16)
Alpha-thalassaemia in Cyprus. (1979) (16)
Murine erythroleukemia cell line GM979 contains factors that can activate silent chromosomal human gamma-globin genes. (1991) (16)
On the induction of fetal hemoglobin in the adult; stress erythropoiesis, cell cycle-specific drugs, and recombinant erythropoietin. (1987) (16)
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, abnormal haemoglobins, and thalassaemia in Yugoslavia. (1966) (16)
Experimental approaches for the study of hemoglobin switching. Proceedings of the Fourth Conference on Hemoglobin Switching. Airlie, Virginia, October 1-3, 1984. (1985) (16)
Development of virus vectors for gene therapy of (cid:1) chain hemoglobinopathies: ﬂanking with a chromatin insulator reduces (cid:2) -globin gene silencing in vivo (2002) (16)
Developmental control of globin gene expression. Proceedings of the Fifth Conference on Hemoglobin Switching. Airlie, Virginia, September 28-October 1, 1986. (1987) (16)
Preemptive therapy for genetic disease (1996) (15)
Erythrocyte function and marrow regulation in hemoglobin Bethesda (beta-145 histidine). (1972) (15)
Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif. (2004) (15)
Haemoglobin M Hyde Park occurring as a fresh mutation: diagnostic, structural, and genetic considerations. (1976) (15)
Globin synthesis in erythroid bursts that mature sequentially in culture. I. Studies in cultures of adult peripheral blood BFU-Es. (1981) (15)
Purification and Identification of Proteins That Bind to the Hereditary Persistence of Fetal Hemoglobin –198 Mutation in the γ-Globin Gene Promoter* (2007) (15)
Two siblings with unusually mild homozygous beta-thalassemia: a didactic example of the effect of a nonallelic modifier gene of the expressivity of a monogenic disorder. (1981) (14)
The higher structure of chromatin in the LCR of the beta-globin locus changes during development. (2009) (14)
Alpha-thalassemia in blacks is due to gene deletion. (1979) (14)
Development of a condensed locus control region cassette and testing in retrovirus vectors for A gamma-globin. (1998) (14)
Butyrate induces expression of transfected human fetal and endogenous mouse embryonic globin genes in GM 979 erythroleukemia cells. (1990) (14)
VARIANTS OF GLUCOSE‐6‐PHOSPHATE DEHYDROGENASE * (1971) (14)
Human CD34+ cell EST database: single-pass sequencing of 402 clones from a directional cDNA library. (1996) (14)
Somatic-Cell Mutation Monitoring System Based on Human Hemoglobin Mutants (1984) (14)
Restriction endonuclease mapping of gamma-delta-beta-globin region in G gamma (beta)+ HPFH and a Chinese A gamma HPFH variant. (1983) (14)
The mechanism of expansion of late erythroid progenitors during erythroid regeneration: target cells and effects of erythropoietin and interleukin-3 (1989) (14)
A haemoglobin switching activity modulates hereditary persistence of fetal haemoglobin (1984) (14)
Extracorporeal treatment with cyanate in sickle cell disease: preliminary observations in four patients. (1976) (14)
Prospects for developing a molecular cure for thalassemia (2005) (13)
Transcriptional potential of the γ-globin gene is dependent on the CACCC box in a developmental stage-specific manner (2006) (13)
Differences of globin transgene expression in stably transfected cell lines and transgenic mice. (2005) (13)
Molecular characterization of a novel form of (A gamma delta beta)zero thalassemia deletion in a Chinese family (1993) (13)
Induction of fetal hemoglobin by cell-cycle-specific drugs and recombinant erythropoietin. (1990) (13)
Genetics of the peloponnesean populations and the theory of extinction of the medieval peloponnesean Greeks (2017) (13)
Integration bias of gammaretrovirus vectors following transduction and growth of primary mouse hematopoietic progenitor cells with and without selection. (2006) (13)
Globin gene switching: insights from studies in somatic heterospecific hybrids and in transgenic mice. (1990) (13)
Functional Validation of a Constitutive Autonomous Silencer Element (2015) (13)
Globin Gene Switching IN VIVO PROTEIN-DNA INTERACTIONS OF THE HUMAN (cid:98) -GLOBIN LOCUS IN ERYTHROID CELLS EXPRESSING THE FETAL OR THE ADULT GLOBIN GENE PROGRAM* (1996) (12)
Serum-cholesterol and thalassemia trait. (1963) (12)
On the Familial Predisposition (2006) (12)
The transcription factor KLF11 can induce γ‐globin gene expression in the setting of in vivo adult erythropoiesis (2007) (12)
Heterogeneity of erythroid precursor cells. Hemoglobin quantitation in single clones by radioimmunoassay. (1981) (12)
Development of viral vectors for gene therapy of beta-chain hemoglobinopathies: optimization of a gamma-globin gene expression cassette. (1999) (12)
Stains for Inclusion Bodies (1974) (12)
Poor stem cell harvest may not always be related to poor mobilization: lessons gained from a mobilization study in patients with β‐thalassemia major (2017) (12)
Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region. (2002) (12)
Structure of haemoglobin Seattle. (1973) (12)
Isozyme patterns in erythrocytes from human fetuses (1977) (12)
Electrophoretic and functional abnormalities of haemoglobin tacoma β30(B12) Arg→Ser (1974) (11)
The minimal promoter plays a major role in silencing of the galago gamma-globin gene in adult erythropoiesis. (2004) (11)
GM 58/8: a monoclonal antibody that identifies a new lineage‐specific determinant expressed by myeloid progenitors (CFU‐GM) and their progeny (1984) (11)
Bone Changes in Thalassaemia Trait (1963) (11)
Disorders of Hemoglobin: Molecular and Cellular Basis of Hemoglobin Switching (2009) (11)
Substitution of the human beta-spectrin promoter for the human agamma-globin promoter prevents silencing of a linked human beta-globin gene in transgenic mice. (1998) (11)
Genetical influences on serum--cholesterol level. (1971) (11)
Hemoglobin ontogenesis: test of the gene excision hypothesis. (1977) (11)
A chromosome 11-linked determinant controls fetal globin expression and the fetal-to-adult globin switch. (1987) (11)
The ontogenesis of hemoglobins in Macaca nemestrina. (1971) (11)
Multiple epsilon-promoter elements participate in the developmental control of epsilon-globin genes in transgenic mice. (1998) (10)
Absence of hemoglobin A in a double heterozygote for F-thalassemia and hemoglobin S. (1967) (10)
Clinical-Scale Genome Editing of the Human BCL11A Erythroid Enhancer for Treatment of the Hemoglobinopathies (2015) (10)
The modulation of Hb F synthesis in adult erythroid progenitor (burst-forming unit) cultures reflects changes in gamma-globin gene transcription and chromatin structure. (1986) (10)
Gene therapy for hemophilia. (2001) (10)
Protein kinase Cα is differentially activated during neonatal and adult erythropoiesis and favors expression of a reporter gene under the control of the Aγ globin‐promoter in cellular models of hemoglobin switching (2007) (10)
The detection and sorting of rare sickle-hemoglobin containing cells in normal human blood (1981) (10)
Effects of human γ‐globin in murine β‐thalassaemia (2006) (10)
Site of the Amino-acid Substitution in Haemoglobin Seattle (αAβ β70 Asp2) (1973) (10)
Superior long-term repopulating capacity of G-CSF+plerixafor-mobilized blood: implications for stem cell gene therapy by studies in the Hbb(th-3) mouse model. (2014) (10)
PSEUDOMOSAICISM IN MALES WITH MILD G.-6-P.D. DEFICIENCY. (1965) (10)
Selection with a regulated cell growth switch increases the likelihood of expression for a linked gamma-globin gene. (2005) (10)
Transcriptional potentials of the beta-like globin genes at different developmental stages in transgenic mice and hemoglobin switching. (2004) (10)
Chromatin insulators and position effects (2003) (9)
Induction of fetal hemoglobin by propionic and butyric acid derivatives: correlations between chemical structure and potency of Hb F induction. (2002) (9)
Coexpression of gamma and beta globin mRNA in cells containing a single human beta globin locus: results from studies using single-cell reverse transcription polymerase chain reaction [published erratum appears in Blood 1994 Aug 15;84(4):1357] (1994) (9)
Electrophoretic diversity of glucose-6-phosphate dehydrogenase among Greeks. (1970) (9)
Monoclonal antibody 53.6 recognizes a novel proliferation-associated antigen encoded on human chromosome 11. (1987) (9)
Gamma gene promoter and enhancer structure in Seattle variant of hereditary persistence of fetal hemoglobin. (1988) (9)
Evidence for the in vivo safety of insulated foamy viral vectors (2016) (9)
Mutation of a transcriptional motif of a distant regulatory element reduces the expression of embryonic and fetal globin genes. (2003) (9)
Tissue isoenzyme alterations in cyanate treated animals. (1973) (9)
Transcription coactivator CBP has direct DNA binding activity and stimulates transcription factor DNA binding through small domains. (2002) (9)
Eastern European (delta beta) zero-thalassemia: molecular characterization of a novel 9.1-kb deletion resulting in high levels of fetal hemoglobin in the adult [see comments] (1994) (9)
Transcriptional regulation of FKLF-2 (KLF13) gene in erythroid cells. (2005) (9)
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced γ globin expression in somatic cell hybrids and induces γ gene expression in adult BFUe cultures (2003) (9)
Autonomous Silencing as Well as Competition Controls γ-Globin Gene Expression during Development (2006) (9)
Coexpression of ϵ, Gγ and Aγ Globin mRNA in Embryonic Red Blood Cells from a Single Copy β-YAC Transgenic Mouse (1995) (9)
beta-YAC transgenic mice for studying LCR function. (1998) (9)
Mapping of a syndrome of X-linked thrombocytopenia with Thalassemia to band Xp11-12: further evidence of genetic heterogeneity of X-linked thrombocytopenia. (2000) (9)
Investigations of a Human Embryonic Globin Gene Silencing Element Using YAC Transgenic Mice (2006) (9)
Butyrate stimulates HbF in adult baboons. (1989) (8)
Cellular regulation of fetal hemoglobin synthesis in man. Investigation of gamma and beta mRNA accumulation in clonal erythroid cultures initiated from erythroid progenitors derived from fetuses, neonates, and adult individuals. (1980) (8)
Functional Interaction between Coactivators CBP / p 300 , PCAF , and Transcription Factor FKLF 2 * (2002) (8)
Experimental approaches for the study of hemoglobin switching : proceedings of the Fourth Conference on Hemoglobin Switching, October 1-3, 1984 (1985) (8)
An international effort to cure a global health problem: A report on the 19th Hemoglobin Switching Conference. (2015) (8)
Hemoglobin switching activity. (1983) (8)
The asynchrony of gamma- and beta-chain synthesis during human erythroid cell maturation. III. gamma- and beta-mRNA in immature and mature erythroid clones. (1981) (8)
Reticulocyte Response in Sickle Cell Anemia Treated With Recombinant Human Erythropoietin : A Double-Blind Study (2003) (8)
Toward a system for detecting somatic-cell mutations. V. Preparation of fluorescent antibodies to hemoglobin hasharon, a human alpha-chain variant. (1981) (8)
Serum factors can modulate the developmental clock of gamma- to beta-globin gene switching in somatic cell hybrids (1993) (7)
A search for β thalassemia mutations in 4000 year old ancient DNAs of Minoan Cretans. (2012) (7)
Frequencies of thalassemia in American blacks. (1977) (7)
Differentiation kinetics and globin gene expression by circulating human BFUe in suspension cultures. (1990) (7)
Cloning and Characterization of a Potential Transcriptional Activator of Human γ-Globin Genes (2001) (7)
Absence of haemoglobin A2 in an adult. (1962) (7)
Acetylation of human fetal hemoglobin occurs throughout erythroid cell maturation. (1984) (7)
Cis-acting sequences that affect the expression of the human fetal gamma-globin genes. (1985) (7)
Evidence foralocus activation region: theformation ofdevelopmentally stable hypersensitive sites inglobin-expressing hybrids (1987) (7)
Hereditary Persistence of Fetal Hemoglobin in Greece (2005) (6)
Modulation of HBF production by erythropoietin. (1989) (6)
DRUGS, ANESTHESIA AND ABNORMAL HEMOGLOBINS * (1968) (6)
Autonomous silencing as well as competition controls gamma-globin gene expression during development. (2006) (6)
Stem cell gene therapy for the beta-chain hemoglobinopathies. Problems and progress. (1999) (6)
Effects of human gamma-globin in murine beta-thalassaemia. (2006) (6)
Genetic studies on southeastern Bantu of Mozambique (1972) (6)
Glucose-6-phosphate dehydrogenase Madrona: a slow electrophoretic glucose-6-phosphate dehydrogenase variant with kinetic characteristics similar to those of normal type. (1968) (6)
Cases of abnormal human hemoglobin produced by de novo mutation. (1988) (6)
Studies of hemoglobin expression in erythroid cells of early human fetuses using anti-gamma- and anti-beta-globin chain fluorescent antibodies. (1983) (6)
Eastern European (delta beta) zero-thalassemia: molecular characterization of a novel 9.1-kb deletion resulting in high levels of fetal hemoglobin in the adult. (1994) (6)
Red cell enzyme polymorphisms in the Greek populations (1975) (5)
The histone deacetylase inhibitor, trichostatin A, reactivates the developmentally silenced gamma globin expression in somatic cell hybrids and induces gamma gene expression in adult BFUe cultures. (2003) (5)
Bone changes in thalassaemia trait; an x-ray appraisal of 55 cases. (1963) (5)
Compounds of the anthracycline family of antibiotics elevate human gamma-globin expression both in erythroid cultures and in a transgenic mouse model. (2010) (5)
Further data from Greece on recombination between the Xg blood group and glucose-6-phosphate dehydrogenase deficiency. (1968) (5)
THE A→C SWITCH IN SHEEP HEMOGLOBIN: IN VITRO STUDIES WITH ERYTHROPOIETIN * (1974) (5)
Gammaretroviral vector integration occurs overwhelmingly within and near DNase hypersensitive sites. (2012) (5)
The linkage relationships of the beta and delta hemoglobin genes. (1977) (5)
The switching from hemoglobin F to hemoglobin A formation in man: parallels between the observations in vivo and the findings in erythroid cultures. (1981) (5)
De novo mutations producing unstable Hbs or Hbs M. (1982) (5)
Haemoglobin Nicosia. AN α‐CHAIN VARIANT AND ITS COMBINATION WITH β‐THALASSAEMIA (1965) (5)
Environmental modification of gene expression: iron deficiency masks erythrocytosis in a female with hemoglobin Olympia. (1978) (5)
Cases of unstable hemoglobin and methemoglobin produced by de novo mutation. (1984) (4)
Human hemoglobin switching: Insights from studies of erythroid cultures (1982) (4)
Juxtaposition of the HPFH2 enhancer is not sufficient to reactivate the gamma-globin gene in adult erythropoiesis. (2005) (4)
Molecular characterization of a novel form of (A gamma delta beta)zero thalassemia deletion in a Chinese family. (1993) (4)
Developmental control of epsilon- and gamma-globin genes. (1998) (4)
53. From GWAS To the Clinic: Genome-Editing the Human BCL11A Erythroid Enhancer for Fetal Globin Elevation in the Hemoglobinopathies (2015) (4)
Hemoglobin-Seattle (alpha-2 beta-2 76-Glu): an unstable hemoglobin causing chronic hemolytic anemia. (1970) (4)
Identification of new genes expressed in a human erythroleukemia cell line. (1996) (4)
Globin Synthesis During Erythroid Cell Maturation in α Thalrssemia (1976) (4)
DRUGS, ANESTHESIA AND ABNORMAL HEMOGLOBINS * (1968) (4)
Role of Gene Order in Developmental Control of Human y- and 3-Globin Gene Expression (2003) (4)
Globin synthesis during erythroid cell maturation in alpha thalassemia. (1976) (4)
In Vivo Search for Butyrate Responsive Sequences Using Transgenic Mice Carrying Gene Promoter Mutants (2002) (4)
Analysis of the Human {-Globin Gene Promoter in Transgenic Mice (2003) (3)
Pharmacologic stimulation of Hb F in patients with sickle cell anemia. (1985) (3)
Asynchronous synthesis of HbF and HbA during erythroblast maturation. II. Studies of G gamma, A gamma, and beta chain synthesis in individual erythroid clones from neonatal and adult BFU-E cultures. (1981) (3)
CELLULAR REGULATION OF FETAL HEMOGLOBIN PRODUCTION * (1980) (3)
Cloning and characterization of a potential transcriptional activator of human gamma-globin genes. (2001) (3)
Haemoglobin Rainier: beta-145 (HC2) tyrosine leads to cysteine and haemoglobin Bethesda: beta-145 (HC2) tyrosine leads to histidine. (1971) (3)
Methemoglobin reduction and the inactive X hypothesis. (1966) (3)
Role of chromatin structure in integration of helper-dependent adenoviral vectors containing the beta-globin locus control region. (2008) (3)
The Molecular Defects of α-Thalassemia in the Filipino (1977) (3)
Sequence of a mosquito ribonucleotide reductase cDNA and evidence for gene amplification in hydroxyurea‐resistant cells (1999) (3)
Serum Factors Can Modulate the Developmental Clock of y- to ,B-Globin Gene Switching in Somatic Cell Hybrids (1993) (3)
A NEW FORM OF β‐THALASSEMIA TRAIT * (1974) (2)
The linkage relationships of the haemoglobin beta, delta and alpha loci with 34 genetic marker systems (1977) (2)
Primary structure of the goat beta-globin locus control region. (1991) (2)
Triplicated a-globin loci in humans (restriction endonuclease mapping/unequal crossing-over/ai thalassemia/polymorphism) (2016) (2)
Analysis of Human γ‐To‐β Switching in Transgenic Mice a (1990) (2)
Single chain alkali resistance in hemoglobin Rainier: beta 145 tyrosine-histidine. (1969) (2)
Extracorporeal treatment of blood with cyanate in primates: physiologic and toxicologic observations. (1974) (2)
Fetal hemoglobin and erythropoietin. (1988) (2)
A transgenic mouse model for studying the induction of fetal hemoglobin in the adult. (1990) (2)
The birth of the American Society of Gene Therapy. (2010) (2)
Molecular Characterization of a Novel Form of ( Arsg ) ' Thalassemia Deletion in a Chinese Family (2003) (2)
Molecular basis on HbH disease in the Mediterranean population (1980) (2)
Investigating the barrier activity of novel, human enhancer-blocking chromatin insulators for hematopoietic stem cell gene therapy. (2021) (2)
Globin chain synthesis in the greek type (A gamma) of hereditary persisitence of fetal haemoglobin. (1975) (2)
Cell lines produce factors that induce fetal hemoglobin in human BFUe-derived colonies. (1992) (2)
Predominant expression of human Agamma--in contrast with beta-globin gene in MEL cells transfected with the construct muLCRAgamma psibeta deltabeta. (1999) (2)
De novo mutations producing unstable hemoglobins or hemoglobins M (1981) (2)
239. Preclinical Studies for the First Hematopoietic Stem Cell (HSC) Gene Editing Trial: Phase 1 Study of Beta-Thalassemia With Autologous Transplantation of Zinc Finger Nuclease-Treated HSC To Upregulate Fetal Hemoglobin (2015) (2)
Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse. (1995) (2)
Haemoglobin Lepore in Cyprus. (1975) (2)
Estimating mutation rates using abnormal human hemoglobins (1984) (2)
Deciphering the Cis- and Trans-regulatory Roles of KLF6 in Primitive Hematopoiesis (2012) (1)
Comprehensive characterization of erythroid-specific enhancers in the genomic regions of human Krüppel-like factors (2013) (1)
De novo mutations producing unstable hemoglobins or hemoglobins M. I. Establishment of a depository and use of data to test for an association of de novo mutation with advanced parental age. (1981) (1)
Developmental role of the tata box in y-globin gene regulation (2000) (1)
Genetic history of the population of Crete (2019) (1)
Hemoglobin switching : proceedings of the Sixth Conference on Hemoglobin Switching, held in Airlie, Virginia, September 24-27, 1988 (1989) (1)
A new form of beta-thalassemia trait. (1974) (1)
association with sickle cell trait A new form of hereditary persistence of fetal hemoglobin in blacks and its (2011) (1)
THALASSAEMIA, GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, SICKLING, (1964) (1)
Comprehensive Investigation of the Molecular Mechanism of Primitive Hematopoiesis Regulating by KLF3 (2012) (1)
In Vivo HSC Transduction and Selection Results in Long-Term, High-Level Expression of Human Gamma Globin in Peripheral Blood Erythrocytes of Mice (2017) (1)
pharmacologic stimulation of Hb F in the adult Treatment of baboon with vinblastine: insights into the mechanisms of (2011) (1)
Investigations of the induction of the goat beta(C) globin gene by erythropoietin: studies in transgenic mice. (2005) (1)
Detection of Somatic Mutants of Hemoglobin (1983) (1)
Regulated expression of human globin genes following transfer with retroviral vectors. (1987) (1)
Regulation of Globin Gene Expression and Erythroid Differentiation by Sp/KLF Factors. (2005) (1)
Substitution of the Human b-Spectrin Promoter for the Human A g-Globin Promoter Prevents Silencing of a Linked Human b-Globin Gene in Transgenic Mice (1998) (1)
Hemoglobin Rainier (beta145 Tyrosine rarr Histidine): Alkali-Resistant Hemoglobin with Increased Oxygen Affinity. (1968) (1)
Hematopoietic Cell Mobilization for Gene Therapy of Adult Patients with Severe Beta-Thalassemia: The Challenge of Splenectomy and the Role of Plerixafor (2011) (1)
Variants of galactose-1-phosphate uridyl transferase in the Greek populations (1977) (1)
The 11th Conference on Hemoglobin Switching (1998) (1)
AUTONOMOUS AND COMPETITIVE MECHANISMS OF HUMAN HEMOGLOBIN SWITCHING (1991) (1)
Thessaly variant of Glucose-6-phosphate Dehydrogenase (2004) (1)
388. Use of the cHS4 Chromatin Insulator to Reduce Oncoretrovirus Vector-Mediated Genotoxicity (2005) (1)
Erythroleukemia Cells and in Transgenic Mice Comparison of Expression of Human Globin Genes Transferred Into Mouse (2010) (0)
in transgenic mice Demonstration of a human epsilon-globin gene silencer with studies (2011) (0)
PDCD2 Knockdown Promoted Induced Erythroid Differentiation in TF-1 Cells (2014) (0)
Hemoglobin Fsynthesis invitro: Evidence forcontrol atthelevel ofprimitive erythroid stemcells (1977) (0)
Reducing retroviral vector genotoxicity with chromatin insulators (2008) (0)
THE LOCUS-CONTROL REGION IN THE GOAT BETA-GLOBIN GNEE CLUSTER (1991) (0)
Hemoglobins and Their Disorders: Human Hemoglobins . H. Franklin Bunn, Bernard G. Forget, and Helen M. Ranney, Eds. Saunders, Philadelphia, 1977. x, 432 pp., illus. $18. (1978) (0)
, George Cells by a Retargeted Adenovirus Vector + Efficient Gene Transfer into Human (2000) (0)
Limitations of G-CSF Mobilization in Splenectomized Patients with Beta-Thalassemia Major: Implications for Thalassemia Gene Therapy. (2009) (0)
the globin synthetic pattern of human BFUe Influence of recombinant hematopoietins and of fetal bovine serum on (2011) (0)
Organization and expression of globin genes : [proceedings of the Second Conference on Hemoglobin Switching, held at Airlie House, Virginia, June 22-26, 1980] (1981) (0)
824. Oncoretroviral Vector Integration Biases in Mouse Hematopoietic Progenitors (2005) (0)
Structural evidence for gamma globin chain synthesis in adult bone marrow cultures. (1976) (0)
Developmental Regulation ofHumany-Globin Genesin Transgenic Mice (1993) (0)
Sequential transduction of human hematopoietic stem cells with retargeted adenovirus vectors devoid of all viral genes encoding the ecotropic retrovirus receptor followed by an ecotropic retrovirus vector (2000) (0)
Cloning of zinc finger proteins homologous to EKLF or Sp1 from human fetal liver and mouse yolk sac (1996) (0)
Functional interaction between CBP/p300 coactivators and transcription factor FKLF-2 (2000) (0)
Greek Cypriot and 132 Turkish Cypriot newborn babies (0)
Structural evidence for γ globin chain synthesis in adult bone marrow cultures (1976) (0)
Author Correction: Perspectives on ENCODE (2022) (0)
neonates HbF and HbA production in erythroid cultures from human fetuses and (2011) (0)
and T somatic cell hybrids . gamma-to beta-globin gene switching in Effects of butyrate and glucocorticoids (1995) (0)
Hydroxamic Acids Derivatives Induce γ Globin Gene Expression in Vivo. (2004) (0)
Developmental Programs ofHumanErythroleukemia Cells: Globin GeneExpression andMethylation (1988) (0)
HAEMOGLOBIN NICOSIA. AN ALPHA-CHAIN VARIANT AND ITS COMBINATION WITH BETA-THALASSAEMIA. (1965) (0)
RoleofGeneOrderinDevelopmental Control ofHuman y- and 3-Globin GeneExpression (1993) (0)
Chromatin Profiling of the Globin Loci of Human ES Cells and ES-Derived Erythroid Cells. (2009) (0)
Talen-Mediated Knock Outs Of Cis and Trans Elements Potentially Involved In Globin Gene Switching (2013) (0)
Molecular Basis of Hemoglobin-HDisease in the (2016) (0)
human zeta-globin gene Identification of a major positive regulatory element located 5 ' to the (2002) (0)
BIOCHEMICAL GENETICS OF GLUCOSE‐6‐PHOSPHATE DEHYDROGENASE VARIATION * (1968) (0)
Coexpression of gamma and beta globin mRNA in cells containing a single human beta globin locus: results from studies using single-cell reverse transcription polymerase chain reaction. (1994) (0)
SerumFactors CanModulate theDevelopmental Clockof y- to,B-Globin GeneSwitching inSomatic CellHybrids (1993) (0)
Editorial help (2004) (0)
Coexpression of y and B Globin mRNA in Cells Containing a Single Human Globin Locus : Results From Studies Using Single-cell Reverse Transcription Polymerase Chain Reaction (0)
Associated With Increased Production of Fetal Hemoglobin (2017) (0)
Erythroid-Specific Intergenic Transcripts Originate from the 200 Kb Region 5′ to the LCR in Erythroleukemia and Human Primary Cells. (2004) (0)
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
MOLECULAR CONTROL OF HUMAN FETAL TO ADULT GLOBIN GENE SWITCHING (1990) (0)
x-thalassaemia inCyprus1 (1979) (0)
Functional Analysis of FOXO3A Involved in Erythroid Differentiation (2012) (0)
81. A Retrovirus Vector Screen for the Identification of Novel Chromatin Insulators and Enhancers (2005) (0)
Mice with an HS3 Core Deletion Embryonic or Fetal Globin Genes in Transgenic between the Locus Control Region and Developmental Specificity of the Interaction (2013) (0)
The molecular defects of alpha-thalassemia in the Filipino. (1977) (0)
Hemoglobin switching activity: target cells and direct evidence for a role of environment to cell interactions in Hb F to Hb A switching. (1983) (0)
present in hemopoietic progenitors Anti-HEL cell monoclonal antibodies recognize determinants that are also (2011) (0)
Hemoglobin Olympia (β20 Valine → Methionine): An Electrophoretically Silent Variant Associated with High Oxygen Affinity and Erythrocytosis (2021) (0)
Use of the cHS4 chromatin insulator in gene transfer vectors (2007) (0)
inhibitors globin gene expression by histone deacetylase γ Induction of human (2003) (0)
Targeted Gene Modification In Hematopoietic Stem Cells: A Potential Treatment For Thalassemia and Sickle Cell Anemia (2013) (0)
B Locus YAC Mice Carrying G Gene Promoter Mutations: Insights into the Mechanism of Action of the -175 HPFH Mutation. (2004) (0)
FRIEND-CELLS DIFFER IN THEIR CAPACITY TO EXPRESS HUMAN GAMMA-GLOBIN (1987) (0)
1001. Use of cHS4 Chromatin Insulator To Improve Efficacy and Safety of Retrovirus Vectors (2004) (0)
2448 Heterogeneity of Erythroid Precursor Cells (2001) (0)
Transcriptional activation of human adult a-globin genes by hypersensitive site-40 enhancer : Function of nuclear factor-binding motifs occupied in erythroid cells ( human ct-globin promoter / genomic footprinting / site-directed mutagenesis / transient expression ) (2005) (0)
Book Review:Human Haemoglobin Variants and Their Characteristics. H. Lehmann, P. A. M. Kynoch (1978) (0)
Hemoglobins and their disorders. (1978) (0)
Haemoglobin M HydeParkoccurring asafresh mutation: diagnostic, structural, andgenetic considerations* (1976) (0)
Human GATA1 Driven By the Human Μicro LCR/β-Globin Promoter Rescues the Erythroid but Not the Megakaryocytic Phenotype Induced in Mice By the Gata1low Mutation (2018) (0)
erythropoietin and hydroxyurea Cooperative enhancement of F-cell formation in baboons treated with (2011) (0)
x-thalassaemia in Cyprus 1 (0)
adult erythroid cell cultures Fetal calf serum contains activities that induce fetal hemoglobin in (2011) (0)
Long-Range Enhancement of β-Globin Gene Expression Is Dependent on Gt Motifs Residing in the HS3 Core Element of the Locus Control Region. (2004) (0)
The Ontogenesis of Hemoglobins in (2005) (0)
A Contigs Strategy of Southern Blot Hybridization: Screening for DNase I Hypersensitive Sites in the 200 Kb Region 5′ to the B-Globin Locus LCR. (2004) (0)
OntheFamilial Predisposition toFavism (1966) (0)
Analysis of the mechanism of action of -117, -175, and -198 nondeletion hpfh mutations in transgenic mice (2000) (0)
3. Safety Assessment of SIN LVs Harboring Chromatin Insulators in the Sensitive Cdkn2a-/- In Vivo Genotoxicity Assay Show Enhancer-Blocking Activity of Specific Insulator Sequences (2015) (0)
Potent Induction of Human γ Globin Gene Expression by Largazole, a New Histone Deacetylase Inhibitor. (2009) (0)
The Sp 1 / KLF family of factors regulates diverse cellular processes including growth and development (2001) (0)
Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene. (1985) (0)
Globin gene expression and hematopoietic differentiation. Proceedings of the Third Conference on Hemoglobin Switching. September 12-15, 1982. (1983) (0)
2. Identification and Ranking of Different Chromatin Insulators to Block Vector-Driven Enhancer-Mediated Insertional Mutagenesis In Vivo (2016) (0)
Plerixafor+G-CSF-Mobilized Blood From Thalassemic Mice Provides High Yields Of Long-Term Repopulating Cells With Enhanced Engrafting Capacity : Implications For Human Stem Cell Gene Therapy (2013) (0)
The A leads to C switch in sheep hemoglobin: in vitro studies with erythropoietin. (1974) (0)
The Thalassaemia Syndromes (1982) (0)
Electrophoretic and functional abnormalities of haemoglobin Tacoma beta30(B12) Arg leads to Ser. (1974) (0)
A tribute to Arno Motulsky. (2018) (0)
Protein kinase Cα induces expression of a reporter gene under the control of the Aγ globin-promoter in cellular models of hemoglobin switching (2007) (0)

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