George Witman | Academic Influence

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George Witman

Computer Science

#8433

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#8866

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Machine Learning

#3454

World Rank

#3497

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Artificial Intelligence

#3754

World Rank

#3809

Historical Rank

Database

#5439

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#5643

Historical Rank

computer-science Degrees

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Computer Science

George Witman's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley
Bachelors Computer Science University of California, Berkeley

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Why Is George Witman Influential?

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According to Wikipedia, George B. Witman is an American biologist currently George F. Booth Chair Professor at University of Massachusetts Medical School and an Elected Fellow of the American Association for the Advancement of Science. His current research is on cilia and flagella biology and has made extensive work involving Chlamydomonas. His highly cited published papers are 1608, 789 and 709.

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George Witman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions (2007) (2504)
Intraflagellar transport (2002) (1407)
Chlamydomonas IFT88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg737, Are Required for Assembly of Cilia and Flagella (2000) (1093)
Proteomic analysis of a eukaryotic cilium (2005) (980)
Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease (2002) (514)
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenance (2002) (479)
The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly (1999) (474)
The vertebrate primary cilium is a sensory organelle. (2003) (453)
A Dynein Light Chain Is Essential for the Retrograde Particle Movement of Intraflagellar Transport (IFT) (1998) (425)
Chlamydomonas flagellar mutants lacking radial spokes and central tubules. Structure, composition, and function of specific axonemal components (1978) (388)
CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content (2010) (368)
Submicromolar levels of calcium control the balance of beating between the two flagella in demembranated models of Chlamydomonas (1984) (332)
Isolation of Chlamydomonas flagella and flagellar axonemes. (1986) (325)
The Chlamydomonas reinhardtii BBSome is an IFT cargo required for export of specific signaling proteins from flagella (2009) (315)
Mutations in Hydin impair ciliary motility in mice (2008) (237)
Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella (2007) (223)
Outer doublet heterogeneity reveals structural polarity related to beat direction in Chlamydomonas flagella (1983) (222)
Radial spoke proteins of Chlamydomonas flagella (2006) (218)
Purification and polypeptide composition of dynein ATPases from Chlamydomonas flagella. (1982) (198)
Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella (2007) (195)
Tubulin requires tau for growth onto microtubule initiating sites. (1976) (192)
Cytoplasmic dynein nomenclature (2005) (185)
Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly (2004) (180)
The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly (1995) (164)
The autosomal recessive polycystic kidney disease protein is localized to primary cilia, with concentration in the basal body area. (2004) (156)
Cilia and Diseases (2014) (156)
Rotation of the central pair microtubules in eukaryotic flagella. (1999) (155)
Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility (2007) (154)
A two-step procedure for efficient electrotransfer of both high-molecular-weight (>400,000) and low-molecular-weight (<20,000) proteins☆ (1987) (145)
The Mr 78,000 intermediate chain of Chlamydomonas outer arm dynein interacts with alpha-tubulin in situ. (1991) (140)
The Chlamydomonas genome project: a decade on. (2014) (139)
Molecular analysis of the gamma heavy chain of Chlamydomonas flagellar outer-arm dynein. (1994) (135)
Chlamydomonas phototaxis. (1993) (133)
Corrigendum: TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport (2016) (131)
Purification of calmodulin from Chlamydomonas: calmodulin occurs in cell bodies and flagella (1980) (130)
A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport. (2004) (126)
Cycling of the signaling protein phospholipase D through cilia requires the BBSome only for the export phase (2013) (124)
A Chlamydomonas outer arm dynein mutant with a truncated beta heavy chain (1993) (121)
Isolated flagellar outer arm dynein translocates brain microtubules in vitro (1987) (120)
Localization of an intermediate chain of outer arm dynein by immunoelectron microscopy. (1990) (119)
Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes (2005) (117)
Mutational analysis of the phototransduction pathway of Chlamydomonas reinhardtii (1995) (114)
The outer dynein arm-docking complex: composition and characterization of a subunit (oda1) necessary for outer arm assembly. (2002) (114)
Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone (2015) (114)
THE SITE OF IN VIVO ASSEMBLY OF FLAGELLAR MICROTUBULES * (1975) (110)
Chlamydomonas flagella. II. The distribution of tubulins 1 and 2 in the outer doublet microtubules. (1972) (106)
Characterization of monoclonal antibodies against Chlamydomonas flagellar dyneins by high-resolution protein blotting. (1985) (106)
Avalanche-like behavior in ciliary import (2013) (104)
Purification and characterization of Chlamydomonas flagellar dyneins. (1986) (102)
The Chlamydomonas reinhardtii ODA3 Gene Encodes a Protein of the Outer Dynein Arm Docking Complex (1997) (101)
The role of retrograde intraflagellar transport in flagellar assembly, maintenance, and function (2012) (99)
Subfractionation of Chlamydomonas 18 S dynein into two unique subunits containing ATPase activity. (1984) (97)
DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC. (2003) (92)
Comparison of the microtubule proteins of neuroblastoma cells, brain, and Chlamydomonas flagella. (1971) (85)
Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm (2015) (84)
Role of cAMP in the reactivation of demembranated ram spermatozoa. (1994) (81)
Functionally significant central-pair rotation in a primitive eukaryotic flagellum (1981) (80)
Oda5p, a novel axonemal protein required for assembly of the outer dynein arm and an associated adenylate kinase. (2004) (80)
NPHP4 controls ciliary trafficking of membrane proteins and large soluble proteins at the transition zone (2014) (79)
Directionality of brain microtubule assembly in vitro. (1974) (78)
The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules (1992) (69)
The 78,000-M(r) intermediate chain of Chlamydomonas outer arm dynein is a microtubule-binding protein (1995) (68)
Introduction to Cilia and Flagella (1990) (68)
Together, the IFT81 and IFT74 N-termini form the main module for intraflagellar transport of tubulin (2016) (68)
HA-tagging of putative flagellar proteins in Chlamydomonas reinhardtii identifies a novel protein of intraflagellar transport complex B. (2009) (67)
IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium (2017) (67)
Synthesis, transport, and utilization of specific flagellar proteins during flagellar regeneration in Chlamydomonas (1982) (66)
Forward and reverse genetic analysis of microtubule motors in Chlamydomonas. (2000) (65)
A unified taxonomy for ciliary dyneins (2011) (64)
ptx1, a nonphototactic mutant of Chlamydomonas, lacks control of flagellar dominance (1993) (63)
Outer arm dynein from trout spermatozoa. Purification, polypeptide composition, and enzymatic properties. (1989) (63)
The motile beta/IC1 subunit of sea urchin sperm outer arm dynein does not form a rigor bond (1992) (63)
Assembly of IFT Trains at the Ciliary Base Depends on IFT74 (2015) (61)
The Catalytic Subunit of the cAMP-dependent Protein Kinase of Ovine Sperm Flagella Has a Unique Amino-terminal Sequence* (1998) (61)
Transport and arrangement of the outer-dynein-arm docking complex in the flagella of Chlamydomonas mutants that lack outer dynein arms. (2001) (60)
Basal bodies and associated structures are not required for normal flagellar motion or phototaxis in the green alga Chlorogonium elongatum (1985) (56)
Dynein and intraflagellar transport. (2015) (55)
LC2, the chlamydomonas homologue of the t complex-encoded protein Tctex2, is essential for outer dynein arm assembly. (1999) (55)
Multiple sites of phosphorylation within the alpha heavy chain of Chlamydomonas outer arm dynein. (1994) (54)
The biochemistry, genetics, and molecular biology of flagellar dynein (1994) (53)
Flagellar waveform and rotational orientation in a Chlamydomonas mutant lacking normal striated fibers (1984) (52)
IC97 is a novel intermediate chain of I1 dynein that interacts with tubulin and regulates interdoublet sliding. (2009) (50)
Axonemal dyneins (1992) (50)
Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes. (1994) (50)
Interspecies conservation of outer arm dynein intermediate chain sequences defines two intermediate chain subclasses. (1995) (49)
Flagellar central pair assembly in Chlamydomonas reinhardtii (2013) (49)
Molecular analysis of the γ heavy chain of Chlamydomonas flagellar outer-arm dynein (1996) (48)
DC3, the Smallest Subunit of the Chlamydomonas Flagellar Outer Dynein Arm-docking Complex, Is a Redox-sensitive Calcium-binding Protein* (2003) (47)
Outer-arm dynein from trout spermatozoa: substructural organization. (1990) (46)
A global analysis of IFT-A function reveals specialization for transport of membrane-associated proteins into cilia (2019) (46)
TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport (2015) (45)
CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice (2015) (44)
Regulation of flagellar motility by the conserved flagellar protein CG34110/Ccdc135/FAP50 (2011) (44)
Differential light chain assembly influences outer arm dynein motor function. (2005) (43)
Proteome of the central apparatus of a ciliary axoneme (2019) (42)
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Masses of chains and sites of ultraviolet-induced vanadate-dependent cleavage. (1987) (42)
Characterization of THB1, a Chlamydomonas reinhardtii Truncated Hemoglobin: Linkage to Nitrogen Metabolism and Identification of Lysine as the Distal Heme Ligand (2014) (41)
Isolation of Chlamydomonas Flagella (2013) (41)
Total internal reflection fluorescence (TIRF) microscopy of Chlamydomonas flagella. (2009) (41)
Cooperative binding of the outer arm-docking complex underlies the regular arrangement of outer arm dynein in the axoneme (2014) (41)
Differential Expression of the Cs and Cα1 Isoforms of the Catalytic Subunit of Cyclic 3′,5′-Adenosine Monophosphate-Dependent Protein Kinase Testicular Cells1 (2001) (40)
DRC3 connects the N-DRC to dynein g to regulate flagellar waveform (2015) (38)
In Situ Localization of N and C Termini of Subunits of the Flagellar Nexin-Dynein Regulatory Complex (N-DRC) Using SNAP Tag and Cryo-electron Tomography* (2015) (37)
A FAP46 mutant provides new insights into the function and assembly of the C1d complex of the ciliary central apparatus (2012) (37)
Reduced tubulin polyglutamylation suppresses flagellar shortness in Chlamydomonas (2015) (36)
A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1) (2018) (36)
The N-terminus of IFT46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA16 (2017) (35)
The photoaffinity probe 8-azidoadenosine 5'-triphosphate selectively labels the heavy chain of Chlamydomonas 12 S dynein. (1984) (35)
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Location of epitopes and protease-sensitive sites. (1988) (33)
Structure of the gamma heavy chain of the outer arm dynein from Chlamydomonas flagella (1988) (32)
Labeling of Chlamydomonas 18 S dynein polypeptides by 8-azidoadenosine 5'-triphosphate, a photoaffinity analog of ATP. (1985) (31)
The unique catalytic subunit of sperm cAMP-dependent protein kinase is the product of an alternative Calpha mRNA expressed specifically in spermatogenic cells. (2000) (31)
Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies. (2015) (31)
Novel touch-induced, Ca(2+)-dependent phobic response in a flagellate green alga. (1994) (29)
A two-step procedure for efficient electrotransfer of both high-molecular-weight (greater than 400,000) and low-molecular-weight (less than 20,000) proteins. (1987) (29)
Cell Motility: Deaf Drosophila Keep the Beat (2003) (29)
Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus (2019) (26)
TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii (2020) (26)
Structure of the alpha and beta heavy chains of the outer arm dynein from Chlamydomonas flagella. Nucleotide binding sites. (1989) (25)
Dynein arm conformation and mechanochemical transduction in the eukaryotic flagellum. (1982) (25)
Novel Role for a Sterol Response Element Binding Protein in Directing Spermatogenic Cell-Specific Gene Expression (2004) (21)
Differential Expression of the C s and Ca1 Isoforms of the Catalytic Subunit of Cyclic 39,59-Adenosine Monophosphate-Dependent Protein Kinase in Testicular Cells 1 (2001) (20)
The Chlamydomonas Flagellum as a Model for Human Ciliary Disease (2009) (20)
Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in Chlamydomonas (2020) (19)
Functional interaction between Chlamydomonas outer arm dynein subunits: the gamma subunit suppresses the ATPase activity of the alpha beta dimer. (1997) (18)
Assay of Chlamydomonas phototaxis. (1995) (17)
An insertional mutant of Chlamydomonas reinhardtii with defective microtubule positioning. (1999) (16)
High-speed digital imaging of ependymal cilia in the murine brain. (2009) (13)
The unity and diversity of the ciliary central apparatus (2019) (12)
Role of calmodulin in the flagellar axoneme: effect of phenothiazines on reactivated axonemes of Chlamydomonas. (1982) (10)
A S FLAGELLA I . Isolation and Electrophoretic Analysis of Microtubules , Matrix , Membranes , and Mastigonemes (1972) (10)
Reactivation of demembranated, cytosol-free ram spermatozoa. (1993) (10)
Purification and characterization of Salmo gairdneri outer arm dynein. (1991) (9)
Consensus nomenclature for dyneins and associated assembly factors (2022) (8)
Isolation of ram sperm flagella. (1995) (8)
14 – Dynein and Intraflagellar Transport (2012) (8)
Diffusion rather than IFT provides most of the tubulin required for axonemal assembly (2018) (7)
Cell motility and behavior (2009) (6)
The N-terminus of IFT 46 mediates intraflagellar transport of outer arm dynein and its cargo-adaptor ODA 16 (2017) (6)
Photoreceptors and Intraflagellar Transport (2004) (5)
Reactivation of Chlamydomonas cell models. (1995) (5)
Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a. (2021) (5)
Characterization of a new oda3 allele, oda3-6, defective in assembly of the outer dynein arm-docking complex in Chlamydomonas reinhardtii (2017) (5)
Diffusion rather than IFT likely provides most of the tubulin required for axonemal assembly. (2020) (4)
Flipping a phosphate switch on kinesin-II to turn IFT around. (2014) (3)
Amoeboid Movement, Cilia, And Flagella (1995) (3)
A S FLAGELLAR MUTANTS LACKING RADIAL SPOKES AND CENTRAL TUBULES Structure , Composition , and Function of Specific Axonemal Components (2003) (3)
Detection of flagellar protein kinases on polyvinylidene difluoride membranes following sodium dodecyl sulfate-polyacrylamide gel electrophoresis. (1995) (2)
Chlamydomonas FAP 70 is a component of the previously uncharacterized ciliary central apparatus projection C 2 a (2021) (1)
No deleterious mutations were found in three genes on human chromosome 17q in patients with Primary Ciliary Dyskinesia (2000) (1)
Structural organization of the C1b projection within the ciliary central apparatus. (2021) (1)
Outer Doublet Related to Beat Heterogeneity Reveals Structural Polarity Direction in Chlamydomonas Flagella (2003) (1)
Preparation and reactivation of demembranated, cytosol-free ram spermatozoa. (1995) (1)
57 – Amoeboid Movement, Cilia, and Flagella (2001) (1)
Structure of the a! and @ Heavy Chains of the Outer Arm Dynein from Chlamydomonas Flagella NUCLEOTIDE BINDING SITES* (2001) (1)
genescandidates for primary ciliary dyskinesia Identification of predicted human outer dynein arm (2006) (1)
Faculty Opinions recommendation of Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification. (2006) (0)
List of Contributors to Volume 3 (2021) (0)
Faculty Opinions recommendation of The ubiquitin conjugation system is involved in the disassembly of cilia and flagella. (2009) (0)
Author response: IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium (2017) (0)
Substructure of the gamma heavy chain from the outer dynein arm of chlamydomonas flagella (1988) (0)
Book Review:The Center of Life. A Natural History of the Cell. L. L. Larison Cudmore (1978) (0)
Faculty Opinions recommendation of Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. (2004) (0)
Faculty Opinions recommendation of Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails. (2003) (0)
Structure of the T Heavy Chain of the Outer Arm Dynein from (1988) (0)
Direct in situ protein tagging in Chlamydomonas reinhardtii utilizing TIM, a method for CRISPR/Cas9-based targeted insertional mutagenesis (2022) (0)
Faculty Opinions recommendation of Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes. (2008) (0)
Characterization of Novel BBS Mutants in Chlamydomonas reinhardtii (2010) (0)
Interspecies Conservation ofOuterArmDynein Intermediate ChainSequences Defines TwoIntermediate ChainSubclasses (1995) (0)
Flagella Ii. the Distribution of Tubulins 1 and in the Outer Doublet Microtubules (0)
Structural organization of the C1b projection within the ciliary central apparatus (2021) (0)
IFT88, an Intraflagellar Transport Protein, is Required for Photoreceptor Outer Segment Assembly in the Mouse (2002) (0)
Evolution of Key Animal and Plant Functions Genome Reveals theChlamydomonasThe (2007) (0)
Do Intraflagellar Transport Proteins Assemble into a Complex in the Vertebrate Retina (2002) (0)
Proteomics of Motile & Primary Cilia: Clues to Human Disease (2006) (0)
The N-terminus of IFT 46 mediates intraflagellar transport of outer arm dynein and its cargoadaptor cargoadaptor cargoadaptor ODA 16 (2017) (0)
Diffusion rather than intraflagellar transport likely provides most of the tubulin required for axonemal assembly in <italic>Chlamydomonas</italic> (2020) (0)
Faculty Opinions recommendation of A mitotic lamin B matrix induced by RanGTP required for spindle assembly. (2006) (0)

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