Gerhard Eisenbrand
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Computer Science Mathematics
Gerhard Eisenbrand's Degrees
- PhD Mathematics ETH Zurich
- Masters Mathematics ETH Zurich
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(Suggest an Edit or Addition)Gerhard Eisenbrand's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases (1999) (740)
- Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors? (2001) (606)
- Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine (1992) (584)
- Influence of dietary nitrate on nitrite content of human saliva: possible relevance to in vivo formation of N-nitroso compounds. (1976) (567)
- Methods of in vitro toxicology. (2002) (427)
- Impact of food processing and detoxification treatments on mycotoxin contamination (2016) (389)
- A review on the beneficial aspects of food processing. (2010) (383)
- 5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione. (2000) (295)
- Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells (2005) (295)
- Food safety for food security: Relationship between global megatrends and developments in food safety (2017) (252)
- Crocus sativus L. (1992) (224)
- Artemisia annua L. (1992) (212)
- Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells (2001) (185)
- Risk characterisation of chemicals in food and diet. (2003) (182)
- Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine (2004) (176)
- Nitrate and nitrite in the diet: how to assess their benefit and risk for human health. (2015) (157)
- Ochratoxin A: induction of (oxidative) DNA damage, cytotoxicity and apoptosis in mammalian cell lines and primary cells. (2005) (155)
- An anthocyanin/polyphenolic‐rich fruit juice reduces oxidative DNA damage and increases glutathione level in healthy probands (2006) (149)
- Food-borne heterocyclic amines. Chemistry, formation, occurrence and biological activities. A literature review. (1993) (146)
- Opinion on the use of plasma processes for treatment of foods. (2013) (145)
- Anti-mitotic properties of indirubin-3′-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest (2001) (144)
- Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate. (2001) (123)
- Contamination of beer with trace quantities of N-nitrosodimethylamine. (1979) (119)
- Nitrate and nitrite in saliva. (1980) (114)
- Risk assessment of substances that are both genotoxic and carcinogenic: Report of an International Conference organized by EFSA and WHO with support of ILSI Europe (2006) (108)
- Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease (2001) (108)
- Ochratoxin A induces oxidative DNA damage in liver and kidney after oral dosing to rats. (2005) (107)
- Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity (2004) (101)
- Polyphenolic apple juice extracts and their major constituents reduce oxidative damage in human colon cell lines. (2006) (99)
- Risk assessment of substances that are both genotoxic and carcinogenic report of an International Conference organized by EFSA and WHO with support of ILSI Europe. (2006) (94)
- Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: results from an intervention study. (2011) (94)
- Anthocyanin/Polyphenolic–Rich Fruit Juice Reduces Oxidative Cell Damage in an Intervention Study with Patients on Hemodialysis (2008) (93)
- Estimation of human exposure to styrene and ethylbenzene. (2000) (90)
- 3',5'-Cyclic nucleotide phosphodiesterase in tumor cells as potential target for tumor growth inhibition. (1993) (88)
- Oxidative stress as a defense mechanism against parasitic infections. (1987) (87)
- Schisandra chinensis (Turcz.) Baill. (1992) (84)
- Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses (2020) (83)
- Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines. (2010) (77)
- Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively‐activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells (2013) (75)
- Automated determination of DNA using the fluorochrome Hoechst 33258. (1985) (74)
- In vivo Role of Cytochrome P450 2E1 and Glutathione-S-Transferase Activity for Acrylamide Toxicokinetics in Humans (2009) (72)
- Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling (2012) (71)
- Indirubin, the red shade of indigo (2006) (71)
- Acrylamide and glycidamide: genotoxic effects in V79-cells and human blood. (2005) (69)
- Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells. (2006) (69)
- From the Insoluble Dye Indirubin towards Highly Active, Soluble CDK2‐Inhibitors (2005) (66)
- Mode of action-based risk assessment of genotoxic carcinogens (2020) (66)
- Handbook Of Chinese Medicinal Plants: Chemistry, Pharmacology, Toxicology (2010) (64)
- Panax notoginseng (Burk.) F. H. Chen (1992) (62)
- N7-glycidamide-guanine DNA adduct formation by orally ingested acrylamide in rats: a dose-response study encompassing human diet-related exposure levels. (2012) (62)
- Profiling of mercapturic acids of acrolein and acrylamide in human urine after consumption of potato crisps. (2012) (61)
- Volatile nitrosamines in food. (1980) (61)
- Risk-Benefit Considerations of Mitigation Measures on Acrylamide Content of Foods – A Case Study on Potatoes, Cereals and Coffee (2008) (57)
- Induction of mitotic gene conversion in Saccharomyces cerevisiae by N-nitrosated pesticides. (1974) (57)
- The influence of glutathione and detoxifying enzymes on DNA damage induced by 2-alkenals in primary rat hepatocytes and human lymphoblastoid cells. (1995) (56)
- Effect of coffee combining green coffee bean constituents with typical roasting products on the Nrf2/ARE pathway in vitro and in vivo. (2012) (56)
- Effects of Hemodialysis, Dialyser Type and Iron Infusion on Oxidative Stress in Uremic Patients (2004) (55)
- Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines. (2006) (53)
- Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation (2018) (52)
- Alpha,beta-unsaturated carbonyl compounds: induction of oxidative DNA damage in mammalian cells. (2003) (51)
- Formation of hydrogen peroxide in cell culture media by apple polyphenols and its effect on antioxidant biomarkers in the colon cell line HT-29. (2009) (51)
- The influence of N7 substituents on the stability of N7-alkylated guanosines. (1985) (50)
- Polyphenolic apple extracts: effects of raw material and production method on antioxidant effectiveness and reduction of DNA damage in Caco-2 cells. (2010) (50)
- Isoflavones as phytoestrogens in food supplements and dietary foods for special medical purposes. Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG)-(shortened version). (2007) (49)
- Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats. (2013) (49)
- Microbial food cultures--opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). (2011) (48)
- (E)-2-hexenal-induced DNA damage and formation of cyclic 1,N2-(1,3-propano)-2'-deoxyguanosine adducts in mammalian cells. (1996) (47)
- Natural flavonoids are potent inhibitors of glycogen phosphorylase. (2006) (47)
- Lung carcinoma induction in BD rats after a single intratracheal instillation of an arsenic‐containing pesticide mixture formerly used in vineyards (1979) (46)
- Genotoxic effects of the α, β-unsaturated aldehydes 2-trans-butenal,2-trans-hexenal and 2-trans, 6-cis-rmnonadienal (1995) (46)
- Consumption of a dark roast coffee decreases the level of spontaneous DNA strand breaks: a randomized controlled trial (2015) (45)
- Apple juice intervention modulates expression of ARE-dependent genes in rat colon and liver (2011) (45)
- Lycobetaine acts as a selective topoisomerase IIβ poison and inhibits the growth of human tumour cells (2001) (44)
- Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing. (2015) (44)
- The reaction of nitrite with pesticides. II. Formation, chemical properties and carcinogenic activity of the N-nitroso derivative of N-methyl-1-naphthyl carbamate (carbaryl). (1975) (42)
- Identification of gaps in knowledge concerning toxicology of 3‐MCPD and glycidol esters (2011) (42)
- Induction of antioxidative Nrf2 gene transcription by coffee in humans: depending on genotype? (2012) (42)
- Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells. (1995) (42)
- Cyclic 3',5'-nucleotide phosphodiesterases: potential targets for anticancer therapy. (2000) (40)
- Biological activity of nitrosated cimetidine. (1979) (39)
- Scutellaria baicalensis Georgi (1992) (39)
- Induction of apoptosis by an inhibitor of cAMP-specific PDE in malignant murine carcinoma cells overexpressing PDE activity in comparison to their nonmalignant counterparts (2007) (39)
- Genotoxic effects of 2-trans-hexenal in human buccal mucosa cells in vivo. (1997) (38)
- Synthesis and cytotoxicity of novel indirubin-5-carboxamides. (2010) (37)
- Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs (2016) (37)
- Toxicological assessment of furocoumarins in foodstuffs. (2007) (37)
- Occurrence of volatile nitrosamines in food: a survey of the West German market. (1980) (37)
- Panax ginseng C.A. Mey. (1992) (36)
- Toxicokinetics of acrylamide in primary rat hepatocytes: coupling to glutathione is faster than conversion to glycidamide (2013) (36)
- Inhibition of GSK3β by indirubins restores HIF‐1α accumulation under prolonged periods of hypoxia/anoxia (2005) (36)
- Gastrodia elata Bl. (1992) (35)
- Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex. (2004) (35)
- Antioxidant effectiveness of phenolic apple juice extracts and their gut fermentation products in the human colon carcinoma cell line caco-2. (2008) (34)
- 7,7'-Diazaindirubin--a small molecule inhibitor of casein kinase 2 in vitro and in cells. (2014) (34)
- Biomarker monitoring of controlled dietary acrylamide exposure indicates consistent human endogenous background (2017) (34)
- Indirubin derivatives modulate TGFβ/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads. (2012) (33)
- Exposure assessment of process-related contaminants in food by biomarker monitoring (2018) (33)
- DNA-damaging potential and glutathione depletion of 2-cyclohexene-1-one in mammalian cells, compared to food relevant 2-alkenals. (2001) (32)
- Monitoring urinary mercapturic acids as biomarkers of human dietary exposure to acrylamide in combination with acrylamide uptake assessment based on duplicate diets (2016) (32)
- Rapid formation of carcinogenic N-nitrosamines by interaction of nitrite with fungicides derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the rat stomach. (1974) (32)
- Urinary excretion of N-nitrosamines in rats and humans. (1982) (31)
- Biological effects of acrylamide after daily ingestion of various foods in comparison to water: a study in rats. (2011) (30)
- Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure (2020) (30)
- Food safety in Europe (FOSIE): risk assessment of chemicals in food and diet (2002) (29)
- Toxicological evaluation of red mould rice. (2006) (29)
- Safety assessment of high pressure treated foods. (2005) (29)
- Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs. (2013) (28)
- Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food. (2018) (27)
- Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. (2017) (27)
- Potential nitrosamine formation and its prevention during biological denitrification of red beet juice. (1997) (27)
- Estrogen-linked 2-chloroethylnitrosoureas: anticancer efficacy in MNU-induced rat mammary carcinoma, uterine activity in mice and receptor interactions. (1986) (27)
- Urinary excretion of N-nitrosodiethanolamine in rats following its epicutaneous and intratracheal administration and its formation in vivo following skin application of diethanolamine. (1981) (27)
- Detection of mutations in bacteria and of DNA damage and amplified DNA sequences in mammalian cells as a systematic test strategy for elucidating biological activities of chemical carcinogens. (1986) (26)
- Coumarin mercapturic acid isolated from rat urine indicates metabolic formation of coumarin 3,4-epoxide. (1991) (26)
- Update of the toxicological assessment of furanocoumarins in foodstuffs (Update of the SKLM statement of 23/24 September 2004)--Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). (2011) (26)
- Induction of DNA strand breaks by nitrosocimetidine. (1980) (25)
- Genotoxicity of glycidamide in comparison to (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide and alpha-acetoxy-N-nitroso-diethanolamine in human blood and in mammalian V79-cells. (2006) (25)
- Genotoxicity of glycidamide in comparison to 3-N-nitroso-oxazolidin-2-one. (2008) (25)
- Some new congeners of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) synthesis of bifunctional analogs and water soluble derivatives and preliminary evaluation of their chemotherapeutic potential (1976) (25)
- Studies on the stability of trialkyl phosphates and di-(2'deoxythymidine) phosphotriesters in alkaline and neutral solution. A model study for hydrolysis of phosphotriesters in DNA and on the influence of a beta hydroxyethyl ester group. (1986) (25)
- Statement on the treatment of food using a pulsed electric field. Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). (2008) (24)
- Formation of nitrite in gastric juice of patients with various gastric disorders after ingestion of a standard dose of nitrate--a possible risk factor in gastric carcinogenesis. (1984) (24)
- Houttuynia cordata Thunb. (1992) (24)
- Urinary excretion of N-nitrosodiethanolamine administered orally to rats. (1978) (23)
- Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and novel derivatives free of positional isomers. Potent inhibitors of cAMP-specific phosphodiesterase and of malignant tumor cell growth. (1998) (23)
- Carcinogenicity in rats of high oral doses of N-nitroso-carbaryl, a nitrosated pesticide. (1976) (23)
- Genotoxic effects of the alpha, beta-unsaturated aldehydes 2-trans-butenal, 2-trans-hexenal and 2-trans, 6-cis-nonadienal. (1995) (22)
- Dicofol degradation to p,p'-dichlorobenzophenone - a potential antiandrogen. (2011) (22)
- Daucus carota L. (1992) (21)
- Assessment of dietary phytoestrogen intake via plant-derived foods in China (2014) (21)
- In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self‐emulsifying drug delivery systems (2014) (21)
- FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients. (2019) (21)
- Coffee consumption rapidly reduces background DNA strand breaks in healthy humans: Results of a short-term repeated uptake intervention study. (2016) (21)
- Chemotherapeutic activity of new 2-chloroethylnitrosoureas in rat L5222 leukemia: comparison of bifunctional and water-soluble derivatives with 1,3-bis(2-chloroethyl)-1-nitrosourea. (1978) (20)
- Andrographis paniculata (Burm. f.) Nees (1992) (20)
- An Approach Towards More Selective Anticancer Agents (1996) (20)
- Fate of 14C-acrylamide in roasted and ground coffee during storage. (2008) (20)
- Areca catechu L. (1992) (20)
- Carcinogenic N-nitrosodimethylamine as a contamination in drugs containing 4-dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one (amidopyrine, aminophenazone). (1979) (20)
- Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia. (2005) (20)
- FEMA GRAS assessment of natural flavor complexes: Mint, buchu, dill and caraway derived flavoring ingredients. (2019) (19)
- DNA adducts and DNA damage by antineoplastic and carcinogenic N-nitrosocompounds (2004) (19)
- Modulation of 3',5'-cyclic AMP homeostasis in human platelets by coffee and individual coffee constituents. (2014) (19)
- Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung. (2001) (19)
- Novel indirubin derivatives, promising anti-tumor agents inhibiting cyclin-dependent kinases. (2004) (19)
- Acrylamide and glycidamide: approach towards risk assessment based on biomarker guided dosimetry of genotoxic/mutagenic effects in human blood. (2005) (18)
- Gas chromatographic determination of N-nitrosoamino acids by trimethylsilylation and single-ion mass fragmentography. (1975) (18)
- DNA damage and repair in the bone marrow of rats treated with four chloroethylnitrosoureas. (1984) (18)
- Carcinogenicity of N-nitrosoephedrine in rats. (1978) (18)
- Synthesis of Potentially Antineoplastic Derivatives of N‐[N‐(2‐Chloroethyl)‐N‐nitrosocarbamoyl]amino Acids (1981) (17)
- Occurrence of N-nitrosamino acids in cured meat products and their efffect on formation of N-nitrosamines during heating. (1978) (17)
- Anticancer activity of new nitrosoureas against Walder carcinosarcoma 256 and DMBA-induced mammary cancer of the rat. (1980) (17)
- Thermally induced process-related contaminants: the example of acrolein and the comparison with acrylamide: opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). (2013) (17)
- Nitrosoureas. Modes of action and perspectives in the use of hormone receptor affinity carrier molecules. (1989) (17)
- Laboratory decontamination and destruction of carcinogens in laboratory wastes: some N-nitrosamines. (1982) (17)
- Syntheses of Potentially Antineoplastic Amides and Esters of N‐[N'‐(2‐Chloroethyl)‐N'‐nitrosocarbamoyl]amino Acids, II (1984) (16)
- The safety evaluation of food flavoring substances: the role of genotoxicity studies (2020) (16)
- Volatile and non-volatile N-nitroso compounds in foods and other environmental media. (1978) (16)
- Carcinogenicity of N-nitroso-3-hydroxypyrrolidine and dose-response study with N-nitrosopiperidine in rats. (1980) (16)
- Development of more selective anti-cancer nitrosoureas. (1988) (15)
- Verbena officinalis L. (1992) (15)
- 7-Benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine, a potent inhibitor of cAMP-specific phosphodiesterase, enhancing nuclear protein binding to the CRE consensus sequence in human tumour cells. (2002) (15)
- FEMA GRAS assessment of natural flavor complexes: Clove, Cinnamon leaf and West Indian bay leaf-derived flavoring ingredients. (2020) (15)
- Contamination of Amines with N‐Nitrosamines (1978) (14)
- Mutagenic and cytotoxic effectiveness of zinc dimethyl and zinc diisononyldithiocarbamate in human lymphocyte cultures. (2001) (14)
- Birefringence and pressure drop for the orifice flow of a polymer solution (1982) (14)
- N-Nitrosodiethanolamine is activated in the rat to an ultimate genotoxic metabolite by sulfotransferase (2004) (14)
- Mechanism of glutathione-mediated DNA damage by the antineoplastic agent 1,3-bis(2-chloroethyl)-N-nitrosourea. (1992) (14)
- Ailanthus altissima (Mill.) Swingle (1992) (14)
- Urinary Excretion of Niacin Metabolites in Humans After Coffee Consumption (2018) (14)
- A method for the determination of N-nitrosoalkanolamines in cosmetics (1988) (14)
- Alcoholdehydrogenase as an activating enzyme for N-nitrosodiethanolamine (NDELA): In vitro activation of NDELA to a potent mutagen in Salmonella typhimurium (2004) (14)
- Reduction of Human Exposure to EnvironmentalN-Nitroso Compounds (1981) (13)
- Fluoro-substituted N-nitrosamines. 2. Metabolism of N-nitrosodiethylamine and of fluorinated analogs in liver microsomal fractions. (1982) (13)
- Physicochemical characterization and in vitro permeation of an indirubin derivative. (2013) (13)
- Biomonitoring of nutritional acrylamide intake by consumers without dietary preferences as compared to vegans (2019) (13)
- FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients. (2019) (12)
- The role of the concept of "history of safe use" in the safety assessment of novel foods and novel food ingredients. Opinion of the Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). (2011) (12)
- Carcinogenic activity in Sprague-Dawley rats of 2-[3-(2-chloroethyl)-3-nitrosoureido]-D-gluco-pyranose (chlorozotocin). (1979) (12)
- Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine with deuterium isotope effects: in vivo induction of DNA single-strand breaks and related in vitro assays. (1998) (12)
- Differential phosphodiesterase expression and cytosolic Ca2+ in human CNS tumour cells and in non‐malignant and malignant cells of rat origin (2005) (12)
- Comparative study on the influence of two 2-chloroethylnitrosoureas with different carbamoylating potential towards glutathione and glutathione-related enzymes in different organs of the rat. (1991) (12)
- Trace analysis of N-nitroso compounds (1970) (12)
- FEMA GRAS assessment of natural flavor complexes: Lavender, Guaiac Coriander-derived and related flavoring ingredients. (2020) (12)
- Corydalis turtschaninovii Bess. f. yanhusuo Y.H. Chou et C.C. Hsü (1992) (12)
- Intracellular localization of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidino-pteridine in membrane structures impeding the inhibition of cytosolic cyclic AMP-specific phosphodiesterase. (2002) (12)
- Metabolism of nitrosamines in vivo (1976) (11)
- A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas. (1987) (11)
- Examination of four newly synthesized 2-chloroethylnitrosoureas in comparison with BCNU, CCNU, MeCCNU, chlorozotocin and hydroxyethyl-CNU in preterminal rat leukemia L 5222 (1979) (11)
- No evidence of carcinogenicity of N-nitrosocimetidine in rats. (1982) (11)
- Anticancer agents: N'-(2-chloroethyl)-N'-nitrosocarbamoyl amino acid derivatives of steroid hormones. (1987) (11)
- Investigations on organ-specific metabolism and genotoxic effects of the urinary bladder carcinogen N-nitrosobutyl-3-carboxypropylamine (BCPN) and its analogs N-nitrosodibutylamine (NDBA) and N-nitrosobutyl-4-hydroxybutylamine (4-OH-NDBA). (1989) (11)
- Water soluble derivatives and bifunctional analogs of the anticancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). (1977) (11)
- Examination of newly synthesized 2-chloroethyl-nitrosoureas on rat leukemia L 5222. (1981) (11)
- N-nitrosamines, including N-nitrosoaminoacids and potential further nonvolatiles. (2008) (11)
- Drug design: nitrosoureas. (1986) (11)
- Sustained Human Background Exposure to Acrolein Evidenced by Monitoring Urinary Exposure Biomarkers. (2019) (10)
- New estradiol-linked nitrosoureas: can the pharmacokinetic properties help to explain the pharmacodynamic activities? (1989) (10)
- Molecular targets of indirubins. (2005) (10)
- Biological activity of N-nitrosodiethanolamine and of potential metabolites which may arise after activation by alcohol dehydrogenase in Salmonella typhimurium, in mammalian cells, and in vivo (2004) (10)
- Genetic effects of some new bifunctional and water-soluble analogs of the anti-cancer agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in Saccharomyces cerevisiae. (1977) (10)
- Occurrence and determination of N-nitroso-3-hydroxypyrrolidine in cured meat products. (1978) (10)
- Proline is not useful as a chemical probe to measure nitrosation in the gastrointestinal tract of patients with gastric disorders characterised by anacidic conditions. (1989) (10)
- Influence of glutathione on the mutagenicity of 2-chloroethylnitrosoureas. Mutagenic potential of glutathione derivatives formed from 2-chloroethylnitrosoureas and glutathione. (1988) (10)
- Occurrence of volatile N-nitrosamines in animal diets (1977) (10)
- Synthesis of N-acetyl-S-(3-coumarinyl)-cysteine methyl ester and HPLC analysis of urinary coumarin metabolites. (2003) (10)
- Biological activity of hydroxylated chloroethylnitrosoureas. (1989) (9)
- Androgen-linked alkylating agents: biological activity in methylnitrosourea-induced rat mammary carcinoma (2005) (9)
- Carcinogenicity testing of low doses of nitrosopyrrolidine and of nitrosobenzthiazuron and nitrosocarbaryl in rats. (1976) (9)
- GRAS 28 flavoring substances (2018) (9)
- N-nitroso compounds in cosmetics, household commodities and cutting fluids (1996) (9)
- FEMA GRAS assessment of natural flavor complexes: Eucalyptus oil and other cyclic ether-containing flavoring ingredients. (2021) (9)
- Selective detection of N-nitrosamines by gas chromatography using a modified microelectrolytic conductivity detector in the pyrolytic mode. (1976) (9)
- Microcystins in algae products used as food supplements. (2008) (9)
- Anticancer nitrosoureas: investigations on antineoplastic, toxic and neoplastic activities. (1984) (9)
- Hormonally active agents in food : symposium (1998) (9)
- Carcinogenicity of methapyrilene hydrochloride, mepyramine hydrochloride, thenyldiamine hydrochloride, and pyribenzamine hydrochloride in Sprague-Dawley rats (2004) (9)
- Carcinogenicity of N-nitrosopyrrolidine: Dose-response study in rats (1977) (9)
- FEMA GRAS assessment of natural flavor complexes: Origanum oil, thyme oil and related phenol derivative-containing flavoring ingredients. (2021) (8)
- Sensitive in vitro test systems to determine androgenic/antiandrogenic activity. (2004) (8)
- Cucurbita moschata Duch. (1992) (8)
- Long-chain N-nitroso-N-methylalkylamines in commercial cosmetics, light-duty dishwashing liquids and household cleaning preparations. (1991) (8)
- Assessing the potential impact on the thyroid axis of environmentally relevant food constituents/contaminants in humans (2016) (8)
- Dose-response study on the carcinogenicity of N-nitrosodiethanolamine in male Sprague-Dawley rats. (1982) (8)
- N-nitrosoalkanolamines in cosmetics. (1991) (8)
- Indirubin-3-Aminooxy-Acetate Inhibits Glycogen Phosphorylase by Binding at the Inhibitor and the Allosteric Site. Broad Specificities of the Two Sites (2005) (8)
- DNA adducts of N-nitrosoureas. (1994) (8)
- Erratum to: Assessing the potential impact on the thyroid axis of environmentally relevant food constituents/contaminants in humans (2016) (8)
- Fluoro-substituted N-nitrosamines. 3. Microsomal metabolism of N-nitrosodibutylamine and of fluorinated analogs. (1982) (7)
- The level of DNA interstrand crosslinking in bone marrow parallels the extent of myelosuppression in mice treated with four chloroethylnitrosoureas (2004) (7)
- Artemisia scoparia Waldst. et Kit. and A. capillaris Thunb. (1992) (7)
- Contribution to the ongoing discussion on fluoride toxicity (2021) (7)
- Synthesis and Characterization of Steroid‐linked N‐(2‐Chloroethyl)nitrosoureas (1989) (7)
- Reduction of Human Exposure to Environmental N-Nitroso- Carcinogens. Examples of Possibilities for Cancer Prevention (1980) (7)
- Assessing the potential impact on the thyroid axis of environmentally relevant food constituents/contaminants in humans (2016) (7)
- Preclinical activity of 17β-[N-[N′-(2-chloroethyl)-N′-nitrosocarbamoyl]-l-alanyl]-5α-dihydrotestosterone (E91) against tumour colony forming units and haematopoietic progenitor cells (1999) (7)
- Characterization of the cell death processes triggered by indirubin derivatives in neuroblastoma cells (2006) (6)
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- Nitrosation of sarcosine, proline and 4-hydroxyproline by exposure to nitrogen oxides. (1982) (4)
- II.3.d Volatile N-nitrosamines in beer and other beverages by direct extraction using a kieselguhr column. (1983) (4)
- Anticarcinogenesis by isothiocyanates, indole-3-carbinol, and Allium thiols. (2000) (4)
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- Fluoro-substituted N-nitrosamines. 4. Comparative genotoxic activities of N-nitrosodibutylamine and three fluorinated analogues in two bacterial systems. (1982) (3)
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- Reduction of anticancer drug toxicity : pharmacologic, biologic,immunologic and gene therapeutic approaches (1995) (2)
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- Heterocyclic aromatic amines: genetic susceptibility (2000) (2)
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- Mechanism of action of the urinary bladder carcinogen N-nitrosobutyl-3-carboxypropylamine. (1991) (2)
- Synthesis of New Bicyclic Oxazaphosphorine Analogues: 2-[Bis(2-chloroethyl)amino]-2-oxo-3-oxa-7-thia-1-aza-2-phosphabicyclo[4.4.0]decane and -[4.3.0]nonane (1992) (2)
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- Answer to Dr. Messina's letter to the editor. (2008) (2)
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- The effect of heavy metal ions on the rate of decomposition of N-ethyl-N-nitrosourea and other carcinogenic N-nitrosamides (1975) (2)
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- Impact of food processing and detoxification treatments on mycotoxin contamination (2016) (1)
- Food allergies and intolerances : Deutsche Forschungsgemeinschaft symposium (1996) (1)
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- Indirubin derivatives inhibit SFKs/Stat signaling associated with apoptosis in human cancer cells (2008) (1)
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- Metabolism of carcinogenic and non-carcinogenic N-nitroso-N-methylaminopyridines. I. Investigations in vitro. (1982) (1)
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- nitrosocarbamoyl)-l l-alanyl)-5-dihydrotestosterone (E91) against Tumour Colony Forming Units and Haematopoietic Progenitor Cells (1999) (1)
- Acrolein and acrylamide: Exposure estimation of food borne toxicants by monitoring mercapturic acids in human urine after consumption of potato crisps (2010) (1)
- In-vivo activation of N-nitrosodiethanolamine and other n-nitroso-2-hydroxyalkylamines by alcohol dehydrogenase and sulfotransferase. (1987) (1)
- Correction to: Mode of action-based risk assessment of genotoxic carcinogens (2020) (1)
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- Pteridine derivatives, processes for their preparation and their use (2002) (0)
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- Infections Causing Human Cancer. By Harald zur Hausen (Ed.). (2008) (0)
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- O6—alkyldeoxyguanosine adduct formation by N-nistroso compounds in calf thymus DNA and in metabolically proficient cell systems (1996) (0)
- 230 Oxidative DNA damage induced by the carcinogenic mycotoxin ochratoxin a in vitro and in vivo (2003) (0)
- General review of approaches to nitrosamine analysis: derivative formation. (1978) (0)
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- Genotoxic activity testing in a laboratory construction for heterotropic biological denitrification of drinking water (1996) (0)
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- Comparison of induction of DNA single-strand breaks and initiation of rat hepatocarcinogenesis by different nitrosamines. (1987) (0)
- FEMA GRAS assessment of natural flavor complexes: Lemongrass oil, chamomile oils, citronella oil and related flavoring ingredients (2023) (0)
- Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses (2020) (0)
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- Erratum to: Assessing the potential impact on the thyroid axis of environmentally relevant food constituents/contaminants in humans (2016) (0)
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- 7th International Symposium of the Division of Experimental Cancer Research (AEK) of the German Cancer Society (1994) (0)
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- V.5 The denitrosation of N-nitroso compounds. (1983) (0)
- Modulation of antioxidant gene expression by apple juice in rats. (2010) (0)
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- Heterocyclic aromatic amines: genotoxicity and DNA adduct formation. (2000) (0)
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- P XVII B.14 Cytotoxic and mutagenic effectiveness of food related α,β-unsaturated carbonyl compounds in mammalian cells (1997) (0)
- Probing the bioactivation mechanism of N-nitrosodiethanolamine (1996) (0)
- The BlueScreen HC assay to predict the genotoxic potential of fragrance materials (2022) (0)
- A BOOK REVIEW : FOOD ALLERGIES AND INTOLERANCES (1996) (0)
- Kinetic of induction and disappearance of DNA-strandbreaks and mutations of different alkylating agents: 3-nitrosooxazolidine-2-one (NOZ-2), 3-nitrosooxazolidin-5-one (NOZ-5) and glycidamide using comet-assay and hPRT-gene-mutation-assay in V79-cells. (2006) (0)
- IV.5.c GC separation of N-nitroso-3-hydroxypyrrolidine and N-nitroso-4-hydroxypiperidine. (1983) (0)
- II.3.b Distillation method for malt. (1983) (0)
- Pennigritrem to Phenole (2006) (0)
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- The health risk of nitrosamines with Gerhard Eisenbrand. (2005) (0)
- Using indigo similar bisindoles for preparing a medicament for inhibiting cyclin-dependent kinases (1999) (0)
- Glutamate to Gyromitrin (2006) (0)
- Abstract B61: Modulation of antioxidant gene expression by a fruit juice rich in polyphenols: an intervention study with hemodialysis patients (2008) (0)
- Protein-Biosynthese to P-Zahl (2006) (0)
- Starkbier to Synthetische Pigmente (2006) (0)
- The role of nutritional factors: colon cancer. (2000) (0)
- Nitrosoureas-Still a Challenge for Developmental Cancer Chemotherapy (1984) (0)
- I.3 Problems of contamination and artefact formation in nitrosamine sampling and analysis. (1983) (0)
- Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure (2020) (0)
- [The reaction of nitrite with pesticides. Formation, chemical properties and carcinogenic activity of the N-nitroso compound of the herbicide N-methyl-N'-(2-benzothiazolyl)-urea (benzthiazuron) (author's transl)]. (1974) (0)
- The Paterson Laboratories, Manchester, England. (1981) (0)
- Trace analysis of volatile nitrosamines by a modified nitrogen-specific detector in pyrolytic mode and by ion-specific determination of heptafluorobutyramines in a gas chromatography-mass spectrometry system. (1976) (0)
- [Tasks and functions of the "Senate Commission for the Evaluation of Healthy Harmless aspects of Food" of the German Research Foundation]. (2004) (0)
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- 631 Inhibition of 3′, 5′-cyclic nucleotide phosphodiesterase as a novel concept in tumour therapy (1995) (0)
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- Pharmacokinetic studies of chloroethylnitrosocarbamoyl-amino acid derivatives in vivo and in vitro. (1993) (0)
- Caloric intake as a modulator of carcinogenicity and anticarcinogenicity. (2000) (0)
- Synthesis and Antineoplasfic Activity of CNC-Cysteamine and Related Compounds * , * * (0)
- Pilze to Polydextrose (2006) (0)
- Galactose to Geruch (2006) (0)
- Analysis of volatile N-nitrosamines in food using nitrogen-specific detection and ion-specific determination of heptafluorobutyramides by gas chromatography/low-resolution mass spectrometry. (1978) (0)
- Our senior editors. Gerhard Eisenbrand: food chemistry and environmental toxicology. (2006) (0)
- Fermentation profiles in the gut and functional effects of food components. (2000) (0)
- Synthesis of New Bicyclic Oxazaphosphorine Analogues: 2-(Bis(2- chloroethyl)amino)-2-oxo-3-oxa-7-thia-1-aza-2-phosphabicyclo (4.4.0) decane and -(4.3.0)nonane. (1992) (0)
- Margarine to Methanol (2006) (0)
- Exposure assessment of process-related contaminants in food by biomarker monitoring (2018) (0)
- Ca to Carcinogenese (2006) (0)
- Antioxidative/preventive capacity of a flavonoid/polyphenolic rich fruit juice reducing oxidative cell damage in healthy probands (2005) (0)
- Monitoring urinary mercapturic acids as biomarkers of human dietary exposure to acrylamide in combination with acrylamide uptake assessment based on duplicate diets (2015) (0)
- N- (N '- (2-chloroethyl) -N'-nitrosocarbamoyl) -oligopeptidestere and amides as well as the method for their preparation (1983) (0)
- Lachgas to Lektine (2006) (0)
- Spargelaroma to Staphylococcus (2006) (0)
- Diagnostik- und Therapieforschung (1986) (0)
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- Antigene to Azorubin (2006) (0)
- Cissampelos pareira L. var. hirsuta (Buch. ex DC.) Formen (1992) (0)
- An approach to an enediyne-netropsin-hybrid compound as a novel antineoplastic agent (2007) (0)
- Sesamin, Sesaminol, Sesamolin to Spargel (2006) (0)
- Steroidester -N-nitroso-carbamoyl amino acids of N- (2-haloethyl) and their peptides, as well as processes for their preparation (1982) (0)
- Aluminium to Antibiotika (2006) (0)
- DMA Damage and Repair in the Bone Marrow of Rats Treated with Four Chloroethylnitrosoureas 1 (2006) (0)
- Correction to: Mode of action-based risk assessment of genotoxic carcinogens (2020) (0)
- OPINION ON Melatonin (2010) (0)
- Editorial: Food is more than a magic word. There is enough food for all of us (2006) (0)
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- Polyphenolic apple extracts and their constituents modulate DNA strand breaks and oxidation damage in human colon carcinoma cells. (2010) (0)
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- HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 5-BROMO-INDIRUBINE (2005) (0)
- DNA DAMAGE AND MERCAPTURIC ACID EXCRETION AFTER LOW DOSE ORAL APPLICATION OF ACRYLAMIDE TO RATS (2012) (0)
- Comprar Handbook of Chinese Medicinal Plants: Chemistry, Pharmacology, Toxicology | Weici Tang | 9783527322268 | Wiley (2009) (0)
- SYNTHESES OF POTENTIALLY ANTINEOPLASTIC AMIDES AND ESTERS OF N‐(N′‐(2‐CHLOROETHYL)‐N′‐NITROSOCARBAMOYL)AMINO ACIDS, II (1984) (0)
- Prevention of exposure to environmental carcinogens (1986) (0)
- Babassufett to Betalaine (2006) (0)
- HUMAN CYCLIN DEPENDENT PROTEIN KINASE 2 IN COMPLEX WITH THE INHIBITOR 4-HYDROXYPIPERINDINESULFONYL-INDIRUBINE (2005) (0)
- [Scientific policy advice on food safety provided by the Senate Commission on Food Safety]. (2010) (0)
- Carnitin to Chitin (2006) (0)
- Effects of isoflavones on breast tissue and the thyroid hormone system in humans: a comprehensive safety evaluation (2018) (0)
- Impact of an acrylamide-niacin adduct on the cellular redox status of human colon carcinoma cells (2014) (0)
- COMPARATIVE STUDY ON THE INFLUENCE OF DIFFERENT CARBAMOYLATING POTENTIAL RELATED ENZYMES IN DIFFERENT ORGANS OF THE RAT TWO 2-CHLOROETHYLNITROSOUREAS WITH TOWARDS GLUTATHIONE AND GLUTATHIONE- (1991) (0)
- II.6.d Drugs, pesticides and miscellaneous industrial chemicals. (1983) (0)
- Induction of antioxidative Nrf2 gene transcription by coffee in humans: depending on genotype? (2012) (0)
- Healthy Coffee and processes for its preparation (2011) (0)
- Abstract 5732: Mercapturic acid excretion and N7-GA-Gua DNA adduct formation after low dose oral application of acrylamide to rats (2012) (0)
- Carcinogenic and Anticarcinogenic Factors in Food: Novel Concepts? - Symposium (Forschungsberichte der DFG) (2000) (0)
- Letter to the Editors regarding "10% body weight (gain) change as criterion for the maximum tolerated dose: A critical analysis". (2023) (0)
- Tea and cancer: what do we know and what do we need to know? (2000) (0)
- Meat, other dietary factors and intestinal ammonia and N-nitro compound formation in relation to colorectal cancer. (2000) (0)
- Toxicokinetics of acrylamide in primary rat hepatocytes: coupling to glutathione is faster than conversion to glycidamide (2013) (0)
- Päonidin to Penitreme (2006) (0)
- Isoenzyme-specific activation of nitrosamines in genetically engineered V79 cells expressing cytochrome P-450 2B1 and 2E1 isoenzyme (1994) (0)
- EdC to Emulsionen (2006) (0)
- Genotoxicity of alpha-acetoxy-N-nitrosodiethanolamine, 3-nitrosooxazolidinones and methyl-3-nitrosooxazolidinones in human blood and V79-cells (2006) (0)
- Foods, phytochemicals, and metabolism: anticarcinogens and carcinogens. (2000) (0)
- Influence of polyphenol-mediated peroxide generation on redox-markers in the colon cell line HT-29 (2008) (0)
- O6-Methyldeoxyguanosine adduct formation by nitroso compounds in calf thymus DNA, rat liver DNA, and in transfected V79 cells expressing CYP2E1 (2007) (0)
- [Cancerogenic nitrite preparations]. (1978) (0)
- Ziziphus jujuba Mill. and Z. spinosa Hu (1992) (0)
- IV.5.e GC-TEA determination of N-nitrosamino acids. (1983) (0)
- Biomarker monitoring of controlled dietary acrylamide exposure indicates consistent human endogenous background (2017) (0)
- Obituary for Rolf Preussmann (1928–2012) (2013) (0)
- Food and animal feed. General aspects. (1983) (0)
- Nisaplin to Nystose (2006) (0)
- Acrylamide – A duplicate diet study (2015) (0)
- Where are the Dangers Lurking (2010) (0)
- Histidin to Hypervitaminosen (2006) (0)
- Lonicera japonica Thunb. (1992) (0)
- Richard Loeppky (1937-2012). (2012) (0)
- In vitro reaction kinetics of Acrolein with DNA to generate N2-Hydroxypropano-2′-deoxyguanosine DNA adducts. (2013) (0)
- Therapeutic efficacy of N-(2-chloroethyl)-N-nitrosocarbamoyl-L-alanine (CNC-ala), CNC-ala-amide (−NH2), CNC-ala-methylamide (−NH−CH3) and their corresponding dipeptide and tripeptide derivatives in autochthonous rat mammary carcinoma (1986) (0)
- Glycyrrhizin (2006) (0)
- Proline isnotuseful asachemical probe tomeasure nitrosation inthegastrointestinal tract ofpatients with gastric disorders characterised byanacidic conditions (1989) (0)
- Endosulfan to Erythrulose (2006) (0)
- Ecklonia kurome Okam. (1992) (0)
- Preclinical activity of 17 beta-[N-[N'-(2-chloroethyl)-N'-nitrosocarbamoyl]-L-alanyl]-5 alpha-dihydrotestosterone (E91) against tumour colony forming units and haematopoietic progenitor cells. (1999) (0)
- Steroid-Linked Aldophosphamides: Activation, Binding Affinities for Androgen Receptors and Effect on Breast Cancer Cells (1995) (0)
- Food chemistry and environmental toxicology (2006) (0)
- Riboflavin to Rundmaul (2006) (0)
- Chapter 18. Posters (2007) (0)
- Title Page / Contents / Foreword (1995) (0)
- Activity of Steroid-Linked Nitrosoureas in a Cell Line Derived from Human Meningioma (1995) (0)
- Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis (2022) (0)
- Zahncremes to ZZulV (2006) (0)
- [Nitrite formation and nitrosation potential of heterotrophic biological denitrification of drinking water in laboratory conditions]. (1996) (0)
- Novel approaches for risk assessment of phytochemicals in food. (2010) (0)
- Nitrosourea and Site- in Mammary Carcinoma (1990) (0)
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What Schools Are Affiliated With Gerhard Eisenbrand?
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