Gertrud Schüpbach
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American geneticist
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Gertrud Schüpbachbiology Degrees
Biology
#978
World Rank
#1693
Historical Rank
#519
USA Rank
Genetics
#456
World Rank
#526
Historical Rank
#189
USA Rank
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Biology
Gertrud Schüpbach's Degrees
- Masters Biology Stanford University
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Why Is Gertrud Schüpbach Influential?
(Suggest an Edit or Addition)According to Wikipedia, Trudi Schüpbach is a Swiss-American molecular biologist. She is an Emeritus Professor of Molecular Biology at Princeton University, where her laboratory studies molecular and genetic mechanisms in fruit fly oogenesis.
Gertrud Schüpbach's Published Works
Published Works
- The drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGFα-like protein (1993) (627)
- Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. (1991) (511)
- cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila (1995) (511)
- Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations. (1989) (460)
- Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster (1987) (398)
- zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. (2007) (321)
- Ectopic activation of torpedo/Egfr, a Drosophila receptor tyrosine kinase, dorsalizes both the eggshell and the embryo. (1997) (309)
- The maternal ventralizing locus torpedo is allelic to faint little ball, an embryonic lethal, and encodes the Drosophila EGF receptor homolog (1989) (272)
- cappuccino and spire: two unique maternal-effect loci required for both the anteroposterior and dorsoventral patterns of the Drosophila embryo. (1989) (264)
- EGF receptor signaling in Drosophila oogenesis. (1999) (225)
- okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis. (1998) (220)
- Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesis (1999) (218)
- The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. (2009) (207)
- Intercellular signaling and the polarization of body axes during Drosophila oogenesis. (1996) (204)
- Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryo (1986) (193)
- cutoff and aubergine Mutations Result in Retrotransposon Upregulation and Checkpoint Activation in Drosophila (2007) (178)
- Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene. (1989) (175)
- Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. (1999) (173)
- The Drosophila TGF-α-like protein Gurken: expression and cellular localization during Drosophila oogenesis (1996) (163)
- Normal female germ cell differentiation requires the female X chromosome to autosome ratio and expression of sex-lethal in Drosophila melanogaster. (1985) (160)
- Activation of a Meiotic Checkpoint during Drosophila Oogenesis Regulates the Translation of Gurken through Chk2/Mnk (2002) (145)
- Three-dimensional epithelial morphogenesis in the developing Drosophila egg. (2013) (143)
- The Spatiotemporal Limits of Developmental Erk Signaling. (2017) (143)
- D-cbl, a Negative Regulator of the Egfr Pathway, Is Required for Dorsoventral Patterning in Drosophila Oogenesis (2000) (131)
- Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis (2004) (127)
- The relationship between ovarian and embryonic dorsoventral patterning in Drosophila. (1994) (125)
- Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline. (1982) (122)
- The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline (2011) (106)
- Localization of gurken RNA in Drosophila oogenesis requires elements in the 5' and 3' regions of the transcript. (2000) (105)
- Cell lineage and development in the larval epidermis of Drosophila melanogaster. (1979) (104)
- Quantitative models of developmental pattern formation. (2006) (104)
- Versatility in signalling: multiple responses to EGF receptor activation during Drosophila oogenesis. (1999) (97)
- Squid hnRNP Protein Promotes Apical Cytoplasmic Transport and Localization of Drosophila Pair-Rule Transcripts (1999) (90)
- The transmembrane region of Gurken is not required for biological activity, but is necessary for transport to the oocyte membrane in Drosophila (1999) (90)
- Half pint regulates alternative splice site selection in Drosophila. (2002) (89)
- Drosophila brca2 Is Required for Mitotic and Meiotic DNA Repair and Efficient Activation of the Meiotic Recombination Checkpoint (2008) (87)
- The Drosophila spn-D gene encodes a RAD51C-like protein that is required exclusively during meiosis. (2003) (87)
- Quantifying the Gurken morphogen gradient in Drosophila oogenesis. (2006) (87)
- Drosophila eggshell is patterned by sequential action of feedforward and feedback loops (2007) (86)
- Encore, a gene required for the regulation of germ line mitosis and oocyte differentiation during Drosophila oogenesis. (1996) (84)
- Localized Requirements for windbeutel and pipe Reveal a Dorsoventral Prepattern within the Follicular Epithelium of the Drosophila Ovary (1998) (82)
- Crag regulates epithelial architecture and polarized deposition of basement membrane proteins in Drosophila. (2008) (78)
- The torpedo (DER) receptor tyrosine kinase is required at multiple times during Drosophila embryogenesis. (1992) (78)
- A combinatorial code for pattern formation in Drosophila oogenesis. (2008) (77)
- Maternal control of Drosophila segmentation gene expression (1986) (74)
- The Drosophila TGF-alpha-like protein Gurken: expression and cellular localization during Drosophila oogenesis. (1996) (74)
- Molecular analysis of the Drosophila EGF receptor homolog reveals that several genetically defined classes of alleles cluster in subdomains of the receptor protein. (1994) (71)
- The Cdc20 (Fzy)/Cdh1-related protein, Cort, cooperates with Fzy in cyclin destruction and anaphase progression in meiosis I and II in Drosophila (2007) (71)
- windbeutel, a gene required for dorsoventral patterning in Drosophila, encodes a protein that has homologies to vertebrate proteins of the endoplasmic reticulum. (1998) (70)
- Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe. (2000) (69)
- Squid, Cup, and PABP55B function together to regulate gurken translation in Drosophila. (2008) (69)
- Dorsoventral patterning in Drosophila oogenesis. (1994) (62)
- Dynamics of Inductive ERK Signaling in the Drosophila Embryo (2015) (52)
- Quantitative analysis of the GAL4/UAS system in Drosophila oogenesis (2006) (49)
- Divergent effects of intrinsically active MEK variants on developmental Ras signaling (2017) (48)
- The egg came first, of course! Anterior-posterior pattern formation in Drosophila embryogenesis and oogenesis. (1989) (48)
- Cct1, a phosphatidylcholine biosynthesis enzyme, is required for Drosophila oogenesis and ovarian morphogenesis (2003) (48)
- Encore facilitates SCF-Ubiquitin-proteasome-dependent proteolysis during Drosophila oogenesis (2003) (46)
- Post-transcriptional regulation of gurken by encore is required for axis determination in Drosophila. (1997) (42)
- In vivo severity ranking of Ras pathway mutations associated with developmental disorders (2017) (40)
- Pattern formation by receptor tyrosine kinases: analysis of the Gurken gradient in Drosophila oogenesis. (2011) (39)
- spn-F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila (2006) (39)
- Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling (2011) (39)
- The role of brinker in eggshell patterning (2006) (37)
- Phantom, a cytochrome P450 enzyme essential for ecdysone biosynthesis, plays a critical role in the control of border cell migration in Drosophila. (2014) (35)
- The embryonic organization of the genital disc studied in genetic mosaics ofDrosophila melanogaster (1978) (33)
- Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesis. (2000) (32)
- Polarized deposition of basement membrane proteins depends on Phosphatidylinositol synthase and the levels of Phosphatidylinositol 4,5-bisphosphate (2014) (32)
- Patterning: JAK-STAT Signalling in the Drosophila Follicular Epithelium (2003) (32)
- Drosophila Cks30A interacts with Cdk1 to target Cyclin A for destruction in the female germline (2005) (31)
- CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila melanogaster (2012) (27)
- Differential effects of Cbl isoforms on Egfr signaling in Drosophila (2006) (26)
- Diversity of epithelial morphogenesis during eggshell formation in drosophilids (2015) (24)
- An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses (2007) (23)
- Modulation of gurken translation by insulin and TOR signaling in Drosophila (2012) (23)
- Stratum, a Homolog of the Human GEF Mss4, Partnered with Rab8, Controls the Basal Restriction of Basement Membrane Proteins in Epithelial Cells. (2017) (22)
- Regulation of somatic myosin activity by Protein Phosphatase 1β controls Drosophila oocyte polarization (2011) (22)
- A study of the female germ line in mosaics ofDrosophila (1978) (21)
- A Gene Expression Screen in Drosophila melanogaster Identifies Novel JAK/STAT and EGFR Targets During Oogenesis (2018) (20)
- Deadlock, a novel protein of Drosophila, is required for germline maintenance, fusome morphogenesis and axial patterning in oogenesis and associates with centrosomes in the early embryo. (2006) (18)
- Systems-level questions in Drosophila oogenesis. (2005) (15)
- A quantitative model of developmental RTK signaling. (2018) (14)
- Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A (2014) (14)
- Modulation of gurken translation by insulin and TOR signaling in Drosophila (2012) (11)
- Drosophila Female Meiosis and Embryonic Syncytial Mitosis Use Specialized Cks and CDC20 Proteins for Cyclin Destruction (2005) (10)
- Signaling between somatic follicle cells and the germline patterns the egg and embryo of Drosophila. (2020) (9)
- Probing for gene specificity in epithelial development. (1998) (9)
- Two signals are better than one: border cell migration in Drosophila. (2001) (9)
- Genetic Screens to Analyze Pattern Formation of Egg and Embryo in Drosophila: A Personal History. (2019) (7)
- Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila. (2016) (4)
- Developmental Biology: Pipe's Smoking Guns (2009) (3)
- Molecular mechanisms underlying cellular effects of human MEK1 mutations (2021) (3)
- Summary Hrb 27 C , Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis (1)
- Stochastic phenotypes in RAS-dependent developmental diseases (2023) (1)
- The Complexities and Unexpected Insights of Developmental Genetic Analysis. (2016) (1)
- CoREST acts as a positive regulator of Notch signaling in the follicle cells of Drosophila (2011) (1)
- Abstract A026: Stochastic phenotypes in RAS-dependent developmental diseases (2023) (0)
- Stratum, a Homolog of the Human GEF Mss4, Partnered with Rab8, Controls the Basal Restriction of Basement Membrane Proteins in Polarized Epithelial Cells (2017) (0)
- The 2010 Genetics Society of America Elizabeth W. Jones Award for Excellence in Education: Utpal Banerjee (2010) (0)
- CoREST acts as a positive regulator of Notch signaling in the follicle cells ofDrosophila melanogaster (2012) (0)
- Characterization of GB73, a new gene involved in the polarized deposition of basement membrane components (2011) (0)
- Summary Encore facilitates SCF-Ubiquitin-proteasome-dependent proteolysis during Drosophila oogenesis (2003) (0)
- The 2004 George W. Beadle Medal. (2004) (0)
- Drosophila Rabconnectin3 alpha and beta regulate trafficking and Notch signaling in the follicle cells (2008) (0)
- Crag is a novel regulator of epithelial architecture and polarized deposition of basement membrane proteins in Drosophila (2008) (0)
- ReviewQuantitative Models of Developmental Pattern Formation (0)
- Drosophila oogenesis. Intercellular signaling and the polarization of body axes during (2011) (0)
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