Gideon Dreyfuss
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Biology
Gideon Dreyfuss's Degrees
- Masters Biochemistry Stanford University
Why Is Gideon Dreyfuss Influential?
(Suggest an Edit or Addition)Gideon Dreyfuss's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- U1 snRNP regulates cancer cell migration and invasion in vitro (2019) (2273)
- Conserved structures and diversity of functions of RNA-binding proteins. (1994) (1888)
- A uniform system for microRNA annotation. (2003) (1825)
- hnRNP proteins and the biogenesis of mRNA. (1993) (1510)
- Messenger-RNA-binding proteins and the messages they carry (2002) (1380)
- RNA‐binding proteins and post‐transcriptional gene regulation (2008) (1168)
- miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (2002) (1152)
- RNA and Disease (2009) (1042)
- Correlation between severity and SMN protein level in spinal muscular atrophy (1997) (1006)
- Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm (1992) (851)
- A novel nuclear structure containing the survival of motor neurons protein. (1996) (777)
- Transport of Proteins and RNAs in and out of the Nucleus (1999) (749)
- A Novel Receptor-Mediated Nuclear Protein Import Pathway (1996) (701)
- The SMN–SIP1 Complex Has an Essential Role in Spliceosomal snRNP Biogenesis (1997) (661)
- The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein (1993) (619)
- SMN Deficiency Causes Tissue-Specific Perturbations in the Repertoire of snRNAs and Widespread Defects in Splicing (2008) (616)
- The Spinal Muscular Atrophy Disease Gene Product, SMN, and Its Associated Protein SIP1 Are in a Complex with Spliceosomal snRNP Proteins (1997) (610)
- Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. (1992) (591)
- Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. (2006) (579)
- A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway (1995) (559)
- A Novel Function for SMN, the Spinal Muscular Atrophy Disease Gene Product, in Pre-mRNA Splicing (1998) (548)
- The pre-mRNA binding K protein contains a novel evolutionarily conserved motif. (1993) (545)
- RNA-binding proteins as developmental regulators. (1989) (543)
- Essential Role for the SMN Complex in the Specificity of snRNP Assembly (2002) (537)
- A nuclear localization domain in the hnRNP A1 protein (1995) (526)
- U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation (2010) (524)
- RNA binding specificity of hnRNP A1: significance of hnRNP A1 high‐affinity binding sites in pre‐mRNA splicing. (1994) (486)
- Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome (1994) (452)
- mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence (1986) (405)
- The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins (2001) (389)
- The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein (1997) (384)
- U1 snRNP Determines mRNA Length and Regulates Isoform Expression (2012) (383)
- Messenger RNA is translated when associated with the cytoskeletal framework in normal and VSV-infected HeLa cells (1981) (370)
- Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins. (1988) (369)
- Numerous microRNPs in neuronal cells containing novel microRNAs. (2003) (368)
- SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. (2001) (358)
- The SMN complex, an assemblyosome of ribonucleoproteins. (2002) (354)
- Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. (2000) (344)
- The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. (1995) (335)
- In vivo and in vitro arginine methylation of RNA-binding proteins (1995) (320)
- Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation. (1988) (314)
- Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. (1986) (306)
- Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities (1988) (302)
- Role of the Nonsense-Mediated Decay Factor hUpf3 in the Splicing-Dependent Exon-Exon Junction Complex (2001) (301)
- hnRNP I, the polypyrimidine tract-binding protein: distinct nuclear localization and association with hnRNAs. (1992) (296)
- Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcription (1984) (294)
- Characterization of dFMR1, a Drosophila melanogaster Homolog of the Fragile X Mental Retardation Protein (2000) (288)
- RNA-binding proteins as regulators of gene expression. (1997) (280)
- Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. (1999) (273)
- SMN mutants of spinal muscular atrophy patients are defective in binding to snRNP proteins. (1999) (272)
- Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein (1992) (269)
- A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export (1997) (262)
- Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them (1996) (260)
- The SMN complex. (2004) (258)
- Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains (1994) (253)
- Transportin-mediated Nuclear Import of Heterogeneous Nuclear RNP Proteins (1997) (250)
- Nuclear proteins that bind the pre-mRNA 3' splice site sequence r(UUAG/G) and the human telomeric DNA sequence d(TTAGGG)n (1993) (249)
- Transportin-SR, a Nuclear Import Receptor for SR Proteins (1999) (245)
- FXR1, an autosomal homolog of the fragile X mental retardation gene. (1995) (244)
- The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity. (1994) (243)
- Structure and function of nuclear and cytoplasmic ribonucleoprotein particles. (1986) (243)
- Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. (2000) (242)
- eIF4A3 is a novel component of the exon junction complex. (2004) (240)
- A Functional Interaction between the Survival Motor Neuron Complex and RNA Polymerase II (2001) (235)
- SMN interacts with a novel family of hnRNP and spliceosomal proteins (2001) (233)
- A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins* (2002) (224)
- Nup153 is an M9‐containing mobile nucleoporin with a novel Ran‐binding domain (1999) (221)
- The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities (1991) (216)
- Translation Is Required to Remove Y14 from mRNAs in the Cytoplasm (2002) (215)
- The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1 (2001) (213)
- Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts. (1989) (211)
- Specific binding of heterogeneous ribonucleoprotein particle protein K to the human c-myc promoter, in vitro. (1993) (209)
- The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signals (1996) (207)
- Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing‐dependent exon–exon junction complex (2001) (206)
- RNA binding specificity of hnRNP proteins: a subset bind to the 3′ end of introns. (1988) (205)
- The Survival of Motor Neurons Protein Determines the Capacity for snRNP Assembly: Biochemical Deficiency in Spinal Muscular Atrophy (2005) (197)
- A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts (1989) (193)
- Ars2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation (2009) (190)
- Transcription-dependent and transcription-independent nuclear transport of hnRNP proteins. (1991) (190)
- A degron created by SMN2 exon 7 skipping is a principal contributor to spinal muscular atrophy severity. (2010) (187)
- General RNA binding proteins render translation cap dependent. (1996) (187)
- Cell type-specific expression of hnRNP proteins. (1995) (185)
- Nuclear export of proteins and RNAs. (1997) (181)
- The SMN complex: an assembly machine for RNPs. (2006) (180)
- Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins (1987) (177)
- tRNA binds to cytochrome c and inhibits caspase activation. (2010) (177)
- Monoclonal antibody characterization of the C proteins of heterogeneous nuclear ribonucleoprotein complexes in vertebrate cells (1984) (176)
- Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies (1984) (175)
- Why do cells need an assembly machine for RNA-protein complexes? (2004) (172)
- Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy (2013) (171)
- Interaction of the RNA‐binding domain of the hnRNP C proteins with RNA. (1992) (164)
- Gemin5, a Novel WD Repeat Protein Component of the SMN Complex That Binds Sm Proteins* (2002) (163)
- Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode. (2003) (161)
- Molecular Functions of the SMN Complex (2007) (154)
- hnRNP proteins: localization and transport between the nucleus and the cytoplasm. (1993) (153)
- Purification of Native Survival of Motor Neurons Complexes and Identification of Gemin6 as a Novel Component* (2002) (152)
- Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro. (1992) (150)
- The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization. (1994) (149)
- Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly. (1984) (148)
- The determinants of RNA-binding specificity of the heterogeneous nuclear ribonucleoprotein C proteins. (1994) (147)
- Specific Sequences of the Sm and Sm-like (Lsm) Proteins Mediate Their Interaction with the Spinal Muscular Atrophy Disease Gene Product (SMN)* (2000) (147)
- hnRNP G: sequence and characterization of a glycosylated RNA-binding protein. (1993) (144)
- The Gemin5 protein of the SMN complex identifies snRNAs. (2006) (141)
- RNA annealing activities in HeLa nuclei. (1994) (138)
- Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. (1999) (130)
- The SMN Complex Is Associated with snRNPs throughout Their Cytoplasmic Assembly Pathway (2002) (127)
- Identification and Characterization of Gemin7, a Novel Component of the Survival of Motor Neuron Complex* (2002) (125)
- Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. (2010) (124)
- Characterization of the major hnRNP proteins from Drosophila melanogaster (1992) (122)
- Transportin: nuclear transport receptor of a novel nuclear protein import pathway. (1996) (119)
- Structure of the Y14-Magoh Core of the Exon Junction Complex (2003) (119)
- Import and export of the nuclear protein import receptor transportin by a mechanism independent of GTP hydrolysis (1998) (117)
- Association of individual hnRNP proteins and snRNPs with nascent transcripts (1993) (115)
- 1H, 13C, and 15N NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins. (1992) (108)
- Structure of a Key Intermediate of the SMN Complex Reveals Gemin2's Crucial Function in snRNP Assembly (2011) (106)
- Gemins modulate the expression and activity of the SMN complex. (2005) (106)
- Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. (2013) (105)
- Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains (2009) (104)
- PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs (2007) (104)
- Ribonucleoprotein particles in cellular processes (1988) (102)
- Rapid-Response Splicing Reporter Screens Identify Differential Regulators of Constitutive and Alternative Splicing (2010) (96)
- Isolation of hnRNP complexes from Drosophila melanogaster (1992) (94)
- RNA transport. (1997) (93)
- The human hnRNP M proteins: identification of a methionine/arginine-rich repeat motif in ribonucleoproteins. (1993) (93)
- snRNAs Contain Specific SMN-Binding Domains That Are Essential for snRNP Assembly (2004) (92)
- Signal sequences that target nuclear import and nuclear export of pre-mRNA-binding proteins. (1995) (92)
- Association of the vav proto-oncogene product with poly(rC)-specific RNA-binding proteins (1995) (88)
- Sequence‐specific interaction of U1 snRNA with the SMN complex (2002) (87)
- The survival motor neuron protein of Schizosacharomyces pombe. Conservation of survival motor neuron interaction domains in divergent organisms. (2000) (81)
- U1 snRNP telescripting regulates a size–function-stratified human genome (2017) (81)
- Ars2 promotes proper replication-dependent histone mRNA 3' end formation. (2012) (78)
- SMN mRNA and protein levels in peripheral blood (2006) (78)
- Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA (2013) (74)
- From Transcript to Protein (1996) (70)
- Distinct Domains in Ribosomal Protein L5 Mediate 5 S rRNA Binding and Nucleolar Localization (*) (1996) (70)
- A Simple Whole Cell Lysate System for in Vitro Splicing Reveals a Stepwise Assembly of the Exon-Exon Junction Complex* (2004) (69)
- Molecular definition of heterogeneous nuclear ribonucleoprotein R (hnRNP R) using autoimmune antibody: immunological relationship with hnRNP P. (1998) (65)
- Inactivation of the SMN complex by oxidative stress. (2008) (64)
- SMN-independent Subunits of the SMN Complex (2007) (61)
- The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure. (2005) (61)
- YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity. (1997) (59)
- Ultraviolet-induced cross-linking of RNA to proteins in vivo. (1989) (59)
- Cell cycle-regulated phosphorylation of the pre-mRNA-binding (heterogeneous nuclear ribonucleoprotein) C proteins. (1993) (59)
- Characterization of Functional Domains of the SMN Proteinin Vivo * (2001) (58)
- Functional Conservation of the Transportin Nuclear Import Pathway in Divergent Organisms (1998) (58)
- RNA binding characteristics of a 16 kDa glycine-rich protein from maize. (1992) (56)
- A cell system with targeted disruption of the SMN gene: functional conservation of the SMN protein and dependence of Gemin2 on SMN. (2001) (56)
- Specific Sequence Features, Recognized by the SMN Complex, Identify snRNAs and Determine Their Fate as snRNPs (2005) (54)
- Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration (2007) (53)
- Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle. (1999) (53)
- A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells. (2019) (52)
- A U1 snRNP-Specific Assembly Pathway Reveals the SMN Complex as a Versatile RNP Exchange (2016) (48)
- Adenovirus proteins associated with mRNA and hnRNA in infected HeLa cells (1987) (46)
- Nuclear mRNA binding proteins couple pre-mRNA splicing and post-splicing events. (2001) (45)
- Localization of the Abelson murine leukemia virus protein in a detergent-insoluble subcellular matrix: architecture of the protein (1981) (43)
- A U 1 snRNP – specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange (2016) (39)
- PUB1: a major yeast poly(A)+ RNA-binding protein. (1993) (39)
- Lymphotropic Herpesvirus saimiri Uses the SMN Complex To Assemble Sm Cores on Its Small RNAs (2005) (38)
- Molecular cloning of cDNA for the nuclear ribonucleoprotein particle C proteins: a conserved gene family. (1986) (37)
- Ce-Y14 and MAG-1, components of the exon–exon junction complex, are required for embryogenesis and germline sexual switching in Caenorhabditis elegans (2004) (37)
- A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis (2012) (37)
- Signal-mediated nuclear export pathways of proteins and RNAs. (1996) (34)
- A novel cell immunoassay to measure survival of motor neurons protein in blood cells (2006) (34)
- Splicing-Correcting Therapy for SMA (2017) (34)
- U1 snRNP Telescripting: Suppression of Premature Transcription Termination in Introns as a New Layer of Gene Regulation. (2019) (34)
- Mutational Definition of RNA-binding and Protein-Protein Interaction Domains of Heterogeneous Nuclear RNP C1* (2001) (33)
- RNP in maize protein (1989) (28)
- The hnRNP proteins (1993) (28)
- Ars 2 Links the Nuclear Cap-Binding Complex to RNA Interference and Cell Proliferation (2010) (28)
- Purification and characterization of proteins of heterogeneous nuclear ribonucleoprotein complexes by affinity chromatography. (1990) (26)
- Interaction of mRNA with proteins in vesicular stomatitis virus-infected cells (1986) (25)
- The Survival Motor Neuron Protein ofSchizosacharomyces pombe (2000) (25)
- Where in the cell is the minor spliceosome? (2008) (24)
- Preparation of efficient splicing extracts from whole cells, nuclei, and cytoplasmic fractions. (2008) (23)
- Positive regulation of ASK1-mediated c-Jun NH2-terminal kinase signaling pathway by the WD-repeat protein Gemin5 (2007) (23)
- Transport of Proteins and RNAs Review in and out of the Nucleus (1999) (22)
- Immunological methods for purification and characterization of heterogeneous nuclear ribonucleoprotein particles. (1990) (22)
- Gemin4 (2000) (21)
- Unwinding with a vengeance (1989) (20)
- Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA (2011) (19)
- Molecular characterization of the protein products of the fragile X syndrome gene and the survival of motor neurons gene. (1996) (14)
- Gemin3 (1999) (12)
- U1 snRNP Telescripting Roles in Transcription and Its Mechanism. (2020) (10)
- The Function of Survival Motor Neuron Complex and Its Role in Spinal Muscular Atrophy Pathogenesis (2017) (8)
- Preparation of heterogeneous nuclear ribonucleoprotein complexes. (1999) (7)
- The ribonucleoprotein structures along the pathway of mRNA formation. (1989) (7)
- Isolation and characterization of RNA-binding proteins from Drosophila melanogaster. (1994) (5)
- NUCLEUS AND GENE EXPRESSION MULTIPROTEIN COMPLEXES, MECHANISTIC CONNECTIONS AND NUCLEAR ORGANIZATION (1999) (5)
- Translation Is Required to Remove Y 14 from mRNAs in the (2002) (5)
- RNA structure. Unwinding with a vengeance. (1989) (2)
- Purification of native SMN complexes and identification of Gemin 6 as a novel component (2001) (2)
- Rapid-Response Splicing Reporter Screens Identify Differential (2010) (2)
- A Cell System with Targeted Disruption of the SMNGene (2001) (2)
- Comprehensive RNP profiling in cells identifies U1 snRNP complexes with cleavage and polyadenylation factors active in telescripting. (2021) (2)
- Myriad RNAs and RNA-Binding Proteins Control Cell Functions, Explain Diseases, and Guide New Therapies. (2020) (1)
- ArticleThe Gemin 5 Protein of the SMN Complex Identifies snRNAs (2006) (1)
- Characterization of a phage library displaying random 22mer peptides (1997) (1)
- Cell cycle-regulated phosphorylation of the pre-mRNA-binding (heterogeneous nuclear ribonucleoprotein) C proteins (1993) (1)
- Ran-regulated interactions of nuclear import and export receptors with nucleoporins (1999) (0)
- From Transcript to Protein Meeting Review (1996) (0)
- Identification ofSrc, Fyn,andLynSH3-Binding Proteins: Implications foraFunction ofSH3Domains (1994) (0)
- Crystal Structure of the Human Y14/Magoh complex (2003) (0)
- 10. A positive cis-element of the human c-myc gene with homo-purine/homo-pyrimidine-like sequence binds proteins with unusual properties (1992) (0)
- hnRNPS and mRNPS (1987) (0)
- Recent studies on hnRNP complexes (2004) (0)
- Table of Contents (1996) (0)
- Leading Edge Review RNA and Disease (2009) (0)
- Review The SMN complex (2004) (0)
- Table of Contents (1995) (0)
- Differential binding of heterogeneous nuclear ribonucleoproteins to mRNA precursors prior to spliceosome assembly in vitro (1992) (0)
- Synthesis of full-gene-length transcripts from the majority of pro- tein-coding genes is not the default process in metazoans; rather, it depends on the suppression of PCPA from cryptic polyadenyla- (2017) (0)
- Table of Contents (1992) (0)
- Differential Binding of Heterogeneous Nuclear Ribonucleoproteins (2003) (0)
- SMN Deficiency in SMA: Splicing Gone Awry (2010) (0)
- Function of SMN protein in the nucleus (1998) (0)
- Shared Mechanisms of RNA Biology (2014) (0)
- Deficiency in SMA : Splicing Gone Awry (2010) (0)
- Results Experimental approach to map the location of Y 14 on spliced mRNAs (0)
- Author response: Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA (2013) (0)
- and hnRNA in infected HeLa cells. Adenovirus proteins associated with mRNA (2013) (0)
- On the occasion of the 20th anniversary of the RNA journal (2015) (0)
- Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRPIA formation (2007) (0)
- G Dreyfuss protein . PUB 1 : a major yeast poly ( A ) + RNA-binding (0)
- Abstract 2257: Thailanstatins: New pre-mRNA splicing inhibitors and potent antiproliferative agents discovered from Burkholderia Thailandensis MSMB43. (2013) (0)
- mRNA processing and disease (2019) (0)
- PUB1: a major yeast poly(A)+ RNA-binding protein (1993) (0)
- crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex (2005) (0)
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