Gilberto de Nucci
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Why Is Gilberto de Nucci Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gilberto De Nucci is a noted Brazilian physician, scientist and university professor in the field of pharmacology. Education He was born in Campinas, state of São Paulo, Brazil. His father was a well-known physician in the city. De Nucci studied medicine at the Medical School of Ribeirão Preto of the University of São Paulo, in Ribeirão Preto , where he also did his initial scientific studies in the Department of Pharmacology. Soon after graduation he moved to London, England. He worked from 1982 to 1985 with Dr. John R. Vane, 1982 Nobel Prize in Physiology and Medicine, at the Wellcome Research Laboratories, in London, England. His doctoral studies were conducted at the Royal College of Surgeons, University of London, in 1986, with Prof. Salvador Moncada. From 1986 to 1988 he was senior scientist at Saint Bartholomew's Hospital Medical College, William Harvey Research Institute.
Gilberto de Nucci's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. (1988) (1438)
- Chronic inhibition of nitric oxide synthesis. A new model of arterial hypertension. (1992) (786)
- Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor. (1989) (305)
- Endothelin‐1 and Endothelin‐3 Release EDRF from Isolated Perfused Arterial Vessels of the Rat and Rabbit (1989) (300)
- Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled. (1988) (250)
- Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat. (1989) (248)
- Effects of acute nitric oxide inhibition on rat glomerular microcirculation. (1991) (217)
- The Fate of Radioiodinated Endothelin‐1 and Endothelin‐3 in the Rat (1989) (164)
- Superoxide anions enhance platelet adhesion and aggregation (1989) (147)
- Effects of different protocol doses of low power gallium-aluminum-arsenate (Ga-Al-As) laser radiation (650 nm) on carrageenan induced rat paw ooedema. (2004) (146)
- Prostaglandin E2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774. (1995) (126)
- Kinins act on B1 or B2 receptors to release conjointly endothelium‐derived relaxing factor and prostacyclin from bovine aortic endothelial cells (1989) (124)
- Endothelin‐1 Participation in Overt and Inflammatory Pain (1989) (124)
- Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test. (1997) (116)
- Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP. (1999) (108)
- Effect of salt intake and inhibitor dose on arterial hypertension and renal injury induced by chronic nitric oxide blockade. (1996) (103)
- Mast cell degranulation induced by two phospholipase A2 homologues: dissociation between enzymatic and biological activities. (1998) (101)
- Renal expression of COX-2, ANG II, and AT1 receptor in remnant kidney: strong renoprotection by therapy with losartan and a nonsteroidal anti-inflammatory. (2004) (100)
- Hydrogen Sulfide-Releasing Therapeutics: Translation to the Clinic. (2017) (91)
- Endothelin‐1 Releases Eicosanoids from Rabbit Isolated Perfused Kidney and Spleen (1989) (90)
- Inhibition of carrageenin‐induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2 (1995) (90)
- Endothelin has potent ulcerogenic and vasoconstrictor actions in the stomach. (1989) (85)
- Sodium excess aggravates hypertension and renal parenchymal injury in rats with chronic NO inhibition. (1994) (83)
- Chronic nitric oxide synthase inhibition aggravates glomerular injury in rats with subtotal nephrectomy. (1995) (83)
- Cyclic GMP-independent mechanisms contribute to the inhibition of platelet adhesion by nitric oxide donor: a role for alpha-actinin nitration. (2006) (82)
- A phase I trial of the bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC3095 in patients with advanced solid malignancies (2006) (81)
- Renal effects of acute and chronic nitric oxide inhibition in experimental diabetes. (1996) (74)
- Pharmacology of Endothelin‐1 in Isolated Vessels: Effect of Nicardipine, Methylene Blue, Hemoglobin, and Gossypol (1989) (74)
- Implications of the use of semicarbazide as a metabolic target of nitrofurazone contamination in coated products (2004) (74)
- The release of nitric oxide and superoxide anion by neutrophils and mononuclear cells from patients with sickle cell anaemia (1996) (73)
- Ticlopidine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study. (2001) (71)
- Role of PKC and CaV1.2 in Detrusor Overactivity in a Model of Obesity Associated with Insulin Resistance in Mice (2012) (66)
- Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2. (2000) (66)
- Endothelial progenitor cell mobilization and platelet microparticle release are influenced by clopidogrel plasma levels in stable coronary artery disease. (2012) (66)
- Lonomia obliqua Caterpillar Spicules Trigger Human Blood Coagulation via Activation of Factor X and Prothrombin (1998) (65)
- Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactions. (1996) (64)
- The relaxation of isolated rabbit corpus cavernosum by the herbal medicine Catuama® and its constituents (2001) (64)
- Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry. (2005) (63)
- Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans. (2002) (60)
- Nitric oxide modulates eosinophil infiltration in antigen-induced airway inflammation in rats. (1998) (59)
- Quantification of carvedilol in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry: application to bioequivalence study. (2005) (56)
- Inflammatory oedema induced by the lys-49 phospholipase A(2) homologue piratoxin-i in the rat and rabbit. Effect of polyanions and p-bromophenacyl bromide. (2000) (56)
- Neuroprotective action of melatonin on neonatal rat motoneurons after sciatic nerve transection (2002) (55)
- Relaxing effects induced by the soluble guanylyl cyclase stimulator BAY 41-2272 in human and rabbit corpus cavernosum. (2003) (54)
- Amlodipine bioequivalence study: quantification by liquid chromatography coupled to tandem mass spectrometry (2001) (54)
- Chronic nitric oxide inhibition as a model of hypertensive heart muscle disease (1996) (54)
- Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale (Catuama®) in healthy volunteers (2005) (53)
- Leucocyte recruitment induced by type II phospholipases A(2) into the rat pleural cavity. (2000) (51)
- A proof‐of‐concept, Phase 2 clinical trial of the gastrointestinal safety of a hydrogen sulfide‐releasing anti‐inflammatory drug (2020) (51)
- Interactions of iloprost and sodium nitroprusside on vascular smooth muscle and platelet aggregation (1989) (51)
- Protective Effects of BAY 41-2272 (sGC Stimulator) on Hypertension, Heart, and Cardiomyocyte Hypertrophy Induced by Chronic L-NAME Treatment in Rats (2006) (51)
- Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin‐induced diabetic mice: evidence of a role for L‐type voltage‐operated Ca2+ channels (2011) (50)
- Vardenafil, but not sildenafil or tadalafil, has calcium‐channel blocking activity in rabbit isolated pulmonary artery and human washed platelets (2008) (50)
- Enalapril does not prevent the myocardial ischemia caused by the chronic inhibition of nitric oxide synthesis. (1995) (50)
- Long‐term nitric oxide deficiency causes muscarinic supersensitivity and reduces β3‐adrenoceptor‐mediated relaxation, causing rat detrusor overactivity (2008) (49)
- Inhibition of eosinophil chemotaxis by chronic blockade of nitric oxide biosynthesis. (1996) (49)
- Pharmacological characterization of a novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum. (2008) (47)
- Mycophenolate Mofetil Reduces Renal Injury in the Chronic Nitric Oxide Synthase Inhibition Model (2001) (47)
- Phoneutria nigriventer (armed spider) venom induces increased vascular permeability in rat and rabbit skin in vivo. (1992) (47)
- Gaseous Mediators in Gastrointestinal Mucosal Defense and Injury (2017) (46)
- Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation. (1989) (45)
- Pharmacological characterization of polycation‐induced rat hind‐paw oedema (1990) (44)
- Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface (2001) (44)
- Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils. (1997) (44)
- Neutrophils and mononuclear cells from patients with chronic granulomatous disease release nitric oxide. (1993) (43)
- Effect of chronic nitric oxide synthesis inhibition on the inflammatory responses induced by carrageenin in rats. (1995) (43)
- Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney. (1998) (42)
- Differential release of eicosanoids by bradykinin, arachidonic acid and calcium ionophore A23187 in guinea‐pig isolated perfused lung (1985) (42)
- Analysis of five streptokinase formulations using the euglobulin lysis test and the plasminogen activation assay. (2004) (42)
- Effect of arginine analogues on rat hind paw oedema and mast cell activation in vitro. (1994) (41)
- MECHANISMS UNDERLYING RELAXATION OF RABBIT AORTA BY BAY 41‐2272, A NITRIC OXIDE‐INDEPENDENT SOLUBLE GUANYLATE CYCLASE ACTIVATOR (2005) (41)
- Nitric oxide has a role in regulating VLA-4-integrin expression on the human neutrophil cell surface. (2003) (40)
- Activation by Phoneutria nigriventer (armed spider) venom of tissue kallikrein‐kininogen‐kinin system in rabbit skin in vivo (1993) (40)
- Small-dose inhaled nitric oxide attenuates hemodynamic changes after pulmonary air embolism in dogs. (1999) (40)
- Attenuation of Hypertension, Cardiomyocyte Hypertrophy, and Myocardial Fibrosis by &bgr;-Adrenoceptor Blockers in Rats Under Long-term Blockade of Nitric Oxide Synthesis (2002) (40)
- Theophylline therapy inhibits neutrophil and mononuclear cell chemotaxis from chronic asthmatic children. (1991) (39)
- The soluble guanylyl cyclase activator BAY 60-2770 ameliorates overactive bladder in obese mice. (2014) (39)
- Lansoprazole quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry. (2003) (39)
- Effect of Tityus serrulatus scorpion venom on the rabbit isolated corpus cavernosum and the involvement of NANC nitrergic nerve fibres (1998) (39)
- The effect of a tachykinin NK1 receptor antagonist, SR140333, on oedema formation induced in rat skin by venom from the Phoneutria nigriventer spider (1996) (39)
- Expression of nitric oxide synthase isoforms and nitrotyrosine immunoreactivity by B‐cell non‐Hodgkin’s lymphomas and multiple myeloma (2001) (38)
- Endothelin‐1 Causes Vasoconstriction and Vasodilation in the Blood Perfused Liver of the Dog (1989) (38)
- Crotoxin induces aggregation of human washed platelets. (1994) (37)
- Upregulation of gp91phox subunit of NAD(P)H oxidase contributes to erectile dysfunction caused by long-term nitric oxide inhibition in rats: reversion by regular physical training. (2010) (37)
- Mechanisms of albuminuria in the chronic nitric oxide inhibition model. (2000) (37)
- Inhaled nitric oxide improves hemodynamics during a venous air infusion (VAI) in dogs (1999) (36)
- Soluble Guanylyl Cyclase (sGC) Degradation and Impairment of Nitric Oxide-Mediated Responses in Urethra from Obese Mice: Reversal by the sGC Activator BAY 60-2770 (2014) (36)
- Different patterns of release of endothelium‐derived relaxing factor and prostacyclin (1992) (36)
- Synthesis and pharmacological evaluations of sildenafil analogues for treatment of erectile dysfunction. (2008) (36)
- Gastric Tolerability and Prolonged Prostaglandin Inhibition in the Brain with a Nitric Oxide-Releasing Flurbiprofen Derivative, NCX-2216 [3-[4-(2-Fluoro-α-methyl-[1,1′-biphenyl]-4-acetyloxy)-3-methoxyphenyl]-2-propenoic acid 4-nitrooxy butyl ester] (2004) (35)
- Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry. (2005) (35)
- Anaphylaxis in guinea pigs induced by ovalbumin aerosol in vivo and in vitro methods. (1987) (35)
- Inflammatory oedema induced by phospholipases A2 isolated from Crotalus durissus sp. in the rat dorsal skin: a role for mast cells and sensory C-fibers. (2003) (35)
- Bromazepam determination in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: a highly sensitive and specific tool for bioequivalence studies. (2004) (35)
- Insulin relaxes bladder via PI3K/AKT/eNOS pathway activation in mucosa: unfolded protein response‐dependent insulin resistance as a cause of obesity‐associated overactive bladder (2013) (35)
- A comparative study on the anti-inflammatory effects of single oral doses of naproxen and its hydrogen sulfide (H2S)-releasing derivative ATB-346 in rats with carrageenan-induced synovitis (2013) (35)
- Activation of Haem-Oxidized Soluble Guanylyl Cyclase with BAY 60-2770 in Human Platelets Lead to Overstimulation of the Cyclic GMP Signaling Pathway (2012) (35)
- Inflammatory mechanisms underlying the rat pulmonary neutrophil influx induced by airway exposure to staphylococcal enterotoxin type A (2005) (35)
- Nifedipine prevents renal injury in rats with chronic nitric oxide inhibition. (1995) (34)
- Comparison of the Effect of Endothelin on Microvessels and Macrovessels in Goldblatt II and Deoxycorticosterone Acetate‐Salt Hypertensive Rats (1990) (34)
- Purification, sequencing and structural analysis of two acidic phospholipases A2 from the venom of Bothrops insularis (jararaca ilhoa). (2006) (34)
- A high-throughput method for determining chloramphenicol residues in poultry, egg, shrimp, fish, swine and bovine using LC-ESI-MS/MS. (2009) (33)
- Reduction of inflammation in rats by diazepam: tolerance development. (2003) (33)
- Dose-dependent beneficial hemodynamic effects of BAY 41-2272 in a canine model of acute pulmonary thromboembolism. (2008) (33)
- Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin. (2004) (33)
- Biochemical and enzymatic characterization of two basic Asp49 phospholipase A2 isoforms from Lachesis muta muta (Surucucu) venom. (2005) (33)
- Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation. (2001) (33)
- Vasoactive mediators released by endothelins. (1992) (32)
- Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study. (2001) (32)
- Exercise training ameliorates the impairment of endothelial and nitrergic corpus cavernosum responses in diabetic rats. (2011) (32)
- Vascular effects of long-term propranolol administration after chronic nitric oxide blockade. (2007) (31)
- Preparation and local anaesthetic activity of benzotriazinone and benzoyltriazole derivatives (1999) (31)
- Simultaneous quantification of GMP, AMP, cyclic GMP and cyclic AMP by liquid chromatography coupled to tandem mass spectrometry. (2007) (30)
- Evidence for the existence of two distinct functions for the inducible NO synthase in the rat kidney: effect of aminoguanidine in rats with 5/6 ablation. (2002) (30)
- Comparative effect of Phoneutria nigriventer spider venom and capsaicin on the rat paw oedema. (2001) (30)
- Effects of Amphetamine on Immune-Mediated Lung Inflammatory Response in Rats (2004) (30)
- Improvement in relaxation response in corpus cavernosum from trained rats. (2004) (30)
- Signalling pathways regulating human neutrophil migration induced by secretory phospholipases A2. (2004) (30)
- Pharmacological characterization of rabbit corpus cavernosum relaxation mediated by the tissue kallikrein‐kinin system (1994) (30)
- Effect of Endothelin‐1 on Arterioles and Venules in vivo (1989) (30)
- Role of nitric oxide on in vitro human eosinophil migration. (2001) (30)
- Anastrozole quantification in human plasma by high-performance liquid chromatography coupled to photospray tandem mass spectrometry applied to pharmacokinetic studies. (2007) (29)
- Phoneutria nigriventer spider venom induces oedema in rat skin by activation of capsaicin sensitive sensory nerves. (1997) (29)
- The role of histamine in human penile erection. (1995) (28)
- Structural and biological characterization of a crotapotin isoform isolated from Crotalus durissus cascavella venom. (2003) (28)
- The beta‐3 adrenoceptor agonist, mirabegron relaxes isolated prostate from human and rabbit: New therapeutic indication? (2015) (28)
- VASORELAXING EFFECTS OF PROPRANOLOL IN RAT AORTA AND MESENTERIC ARTERY: A ROLE FOR NITRIC OXIDE AND CALCIUM ENTRY BLOCKADE (2006) (28)
- Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide (2008) (28)
- Protective effects of exogenous and endogenous hydrogen sulfide in mast cell‐mediated pruritus and cutaneous acute inflammation in mice (2017) (28)
- Quantification of isosorbide 5-mononitrate in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization. (2006) (28)
- Fluoxetine Bioequivalence Study: Quantification of Fluoxetine and Norfluoxetine by Liquid Chromatography Coupled to Mass Spectrometry (1999) (28)
- Alkaline buffers release EDRF from bovine cultured aortic endothelial cells (1991) (28)
- Inflammatory oedema induced by Lachesis muta muta (Surucucu) venom and LmTX-I in the rat paw and dorsal skin. (2009) (27)
- Prostaglandin biosynthesis in the microcirculation: regulation by endothelial and non-endothelial factors. (1993) (27)
- NON‐SPECIFIC INHIBITORS OF NITRIC OXIDE SYNTHASE CAUSE MYOCARDIAL NECROSIS IN THE RAT (1997) (26)
- Verapamil quantification in human plasma by liquid chromatography coupled to tandem mass spectrometry. An application for bioequivalence study. (2005) (26)
- Fluconazole bioequivalence study: quantification by tandem mass spectrometry. (1999) (26)
- Expression and activity of nitric oxide synthase isoforms in rat brain during the development of experimental allergic encephalomyelitis. (2002) (26)
- Simultaneous measurement of endothelium‐derived relaxing factor by bioassay and guanylate cyclase stimulation (1989) (26)
- Pharmacological characterization of kinin-induced relaxation of human corpus cavernosum. (1998) (26)
- Mechanisms Involved in the Enhancement of Allergic Airways Neutrophil Influx by Permanent C-Fiber Degeneration in Rats (2005) (26)
- Effect of therapy with recombinant human interferon-gamma on the release of nitric oxide by neutrophils and mononuclear cells from patients with chronic granulomatous disease. (1996) (26)
- Involvement of vanilloid receptors and purinoceptors in the Phoneutria nigriventer spider venom-induced plasma extravasation in rat skin. (2000) (25)
- Acute pulmonary inflammation induced by exposure of the airways to staphylococcal enterotoxin type B in rats. (2006) (25)
- The effect of Phoneutria nigriventer (armed spider) venom on arterial blood pressure of anaesthetised rats (1996) (25)
- Nitric oxide may underlie learned fear in the elevated T-maze (2001) (25)
- Activation of soluble guanylyl cyclase by BAY 58-2667 improves bladder function in cyclophosphamide-induced cystitis in mice. (2016) (25)
- Ex vivo evidence for PGE2 and LTB4 involvement in cutaneous leishmaniasis: relation with infection status and cytokine production (1996) (25)
- Quantification of betamethasone in human plasma by liquid chromatography-tandem mass spectrometry using atmospheric pressure photoionization in negative mode. (2005) (24)
- Comparison of two marketed nifedipine modified-release formulations: an exploratory clinical food interaction study. (2008) (24)
- Synthesis of substituted benzamides as anti-inflammatory agents that inhibit preferentially cyclooxygenase 1 but do not cause gastric damage. (2001) (24)
- Plasma hydroxy-metronidazole/metronidazole ratio in patients with liver disease and in healthy volunteers. (1995) (24)
- Evaluation of the relaxant effect of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in isolated detrusor smooth muscle. (2010) (24)
- Superoxide dismutase isoforms 1 and 2 in lumbar spinal cord of neonatal rats after sciatic nerve transection and melatonin treatment. (2005) (24)
- Clonazepam quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study. (2007) (24)
- Role of nitric oxide on the increased vascular permeability and neutrophil accumulation induced by staphylococcal enterotoxin B into the mouse paw. (2001) (22)
- Superoxide Dismutase Cooperates with Prostacyclin to Inhibit Platelet Aggregation: a Comparative Study in Washed Platelets and Platelet Rich Plasma (1991) (22)
- Lisinopril quantification in human plasma by liquid chromatography-electrospray tandem mass spectrometry. (2004) (22)
- Phoneutria nigriventer spider venom activates 5‐HT4 receptors in rat‐isolated vagus nerve (2003) (22)
- Development Of An Experimental Model Of Liver Cirrhosis In Rabbits (2000) (21)
- Effect of the inhibition of nitric oxide biosynthesis on allergen-induced airway inflammation in rats (1996) (21)
- Analysis of nitrofuran metabolic residues in salt by liquid chromatography–tandem mass spectrometry (2004) (21)
- Biochemical characterization of a vascular smooth muscle contracting polypeptide purified from Phoneutria nigriventer (armed spider) venom. (1993) (21)
- Relaxation of rabbit corpus cavernosum by selective activators of voltage-gated sodium channels: role of nitric oxide-cyclic guanosine monophosphate pathway. (2003) (20)
- Pharmacological characterisation of the relaxation induced by the soluble guanylate cyclase activator, BAY 60‐2770 in rabbit corpus cavernosum (2015) (20)
- Atypical β-Adrenoceptor Subtypes Mediate Relaxations of Rabbit Corpus Cavernosum (2004) (20)
- Determination of Pantoprazole in Human Plasma by LC-MS-MS Using Lansoprazole as Internal Standard (2004) (20)
- Development of cardiomyocyte hypotrophy in rats under prolonged treatment with a low dose of a nitric oxide synthesis inhibitor. (2000) (20)
- Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids (2020) (20)
- Isolation and partial characterization of a polypeptide from Phoneutria nigriventer spider venom that relaxes rabbit corpus cavernosum in vitro. (1996) (19)
- Role of Substance P and Bradykinin in Acute Pancreatitis Induced by Secretory Phospholipase A2 (2008) (19)
- Reactivity of mesenteric and aortic rings from trained rats fed with high caloric diet. (2007) (19)
- Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle. (2010) (19)
- Long‐term administration of BAY 41‐2272 prevents bladder dysfunction in nitric oxide‐deficient rats (2011) (19)
- EFFECT OF BAY 41‐2272 IN THE PULMONARY HYPERTENSION INDUCED BY HEPARIN–PROTAMINE COMPLEX IN ANAESTHETIZED DOGS (2007) (19)
- Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies. (2001) (19)
- The mechanisms and significance of the coupled release of endothelium-derived relaxing factor (EDRF) and prostacyclin (PGI2) from endothelial cells. (1991) (19)
- Nevirapine quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study. (2002) (19)
- Nonadrenergic, noncholinergic relaxation of human isolated corpus cavernosum induced by scorpion venom. (2001) (19)
- Tetrodotoxin-insensitive electrical field stimulation-induced contractions on Crotalus durissus terrificus corpus cavernosum (2017) (19)
- Simultaneous determination of dextromethorphan, dextrorphan and doxylamine in human plasma by HPLC coupled to electrospray ionization tandem mass spectrometry: application to a pharmacokinetic study. (2012) (19)
- Role of chondroitin 4‐sulphate as a receptor for polycation induced human platelet aggregation (1996) (19)
- Tadalafil for the treatment of benign prostatic hyperplasia (2019) (18)
- Sequence and structure‐activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum (2003) (18)
- Expression of nitric oxide synthases and in vitro migration of eosinophils from allergic rhinitis subjects. (2002) (18)
- Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration. (2001) (18)
- Effects of Low‐Level Laser Therapy (LLLT) and Diclofenac (Topical and Intramuscular) as Single and Combined Therapy in Experimental Model of Controlled Muscle Strain in Rats (2013) (18)
- Bioequivalence study of two enalapril maleate tablet formulations in healthy male volunteers Pharmacokinetic versus pharmacodynamic approach (1996) (18)
- Immunolocalization of nitric oxide synthase isoforms in human archival and rat tissues, and cultured cells (2011) (18)
- Prolonged therapy with the soluble guanylyl cyclase activator BAY 60-2770 restores the erectile function in obese mice. (2014) (17)
- The Evolutionary Implications of Hemipenial Morphology of Rattlesnake Crotalus durissus terrificus (Laurent, 1768) (Serpentes: Viperidae: Crotalinae) (2013) (17)
- Inflammatory responses induced by poly-l-arginine in rat lungsin vivo (1993) (17)
- Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat. (1999) (17)
- Effect of Captopril on the bradykinin‐induced release of prostacyclin from guinea‐pig lungs and bovine aortic endothelial cells (1988) (17)
- Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training (2004) (17)
- Role of kinins and nitric oxide on the rabbit arthritis induced by Bothrops jararaca venom. (2000) (17)
- Terbinafine Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled to Electrospray Tandem Mass Spectrometry: Application to a Bioequivalence Study (2001) (16)
- Activation of tissue kallikrein-kininogen-kinin system in rabbit skin by a fraction isolated from Phoneutria nigriventer (armed spider) venom. (1993) (16)
- Purification and initial characterization of a novel protein with factor Xa activity from Lonomia obliqua caterpillar spicules. (2005) (16)
- Effects of neonatal capsaicin treatment in the neutrophil production, and expression of preprotachykinin-I and tachykinin receptors in the rat bone marrow (2006) (16)
- Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice (2015) (16)
- Long‐term oral treatment with BAY 41‐2272 ameliorates impaired corpus cavernosum relaxations in a nitric oxide‐deficient rat model (2011) (16)
- The synthesis of eicosanoids induced by anaphylaxis in guinea-pig isolated lungs perfused via the trachea. (1986) (15)
- Mechanisms underlying the inhibitory effects of lipopolysaccharide on human platelet adhesion (2010) (15)
- Comparative relaxing effects of sildenafil, vardenafil, and tadalafil in human corpus cavernosum: contribution of endogenous nitric oxide release. (2009) (15)
- Role of kinins and sensory neurons in the rat pleural leukocyte migration induced by Phoneutria nigriventer spider venom (2002) (15)
- Prediction and biochemical characterization of intrinsic disorder in the structure of proteolysis-inducing factor/dermcidin. (2007) (15)
- Role of Endothelin-1 and Thromboxane A2 in the Pulmonary Hypertension Induced by Heparin–Protamine Interaction in Anesthetized Dogs (2004) (15)
- The role of nitric oxide on the relaxations of rabbit corpus cavernosum induced by Androctonus australis and Buthotus judaicus scorpion venoms. (2001) (14)
- Impact of Bariatric Surgery on the Pharmacokinetics Parameters of Amoxicillin (2018) (14)
- The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells (2001) (14)
- Differential protein expression patterns obtained by mass spectrometry can aid in the diagnosis of Hodgkin's disease. (2007) (14)
- Platelets induce human umbilical vein endothelial cell proliferation through P-selectin. (2000) (14)
- Dissimilarity between prostaglandin E1 and nitric oxide donors as potentiators of plasma exudation in the rabbit skin in vivo. (1995) (14)
- Determination of 21-hydroxydeflazacort in human plasma by high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry. Application to bioequivalence study. (2000) (14)
- Nitroflurbiprofen, a new nonsteroidal anti-inflammatory, ameliorates structural injury in the remnant kidney. (1998) (14)
- Increased cyclic guanosine monophosphate synthesis and calcium entry blockade account for the relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in the rabbit penile urethra. (2008) (14)
- Inflammatory oedema induced by the Lys-49 phospholipase A2 homologue piratoxin-i in the rat and rabbit (2000) (14)
- Do ETA Receptors Participate in the Hemodynamic and Renal Effects of Chronic Nitric Oxide Blockade? (1995) (14)
- Determination of minocycline in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry: application to bioequivalence study. (2001) (14)
- Quantification of the bombesin/gastrin releasing peptide antagonist RC-3095 by liquid chromatography-tandem mass spectrometry. (2005) (13)
- The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. (2010) (13)
- Bioequivalence Study of Finasteride (2001) (13)
- Activation by Phoneutria nigriventer spider venom of autonomic nerve fibers in the isolated rat heart. (1998) (13)
- Inhibition of human platelet aggregation by eosinophils. (2013) (13)
- Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide. (2006) (13)
- Inhibitory effects on human eosinophil chemotaxis in vitro by BAY 41-2272, an activator of nitric oxide-independent site of soluble guanylate cyclase. (2005) (13)
- Phosphodiesterase-9 (PDE9) inhibition with BAY 73-6691 increases corpus cavernosum relaxations mediated by nitric oxide–cyclic GMP pathway in mice (2013) (12)
- Characterization of the urinary bladder dysfunction in renovascular hypertensive rats (2011) (12)
- Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of corpus cavernosum from the South American rattlesnake Crotalus durissus terrificus. (2011) (12)
- Comparative bioavailability of two atenolol tablet formulations in healthy male volunteers after a single dose administration. (1997) (12)
- Protective effect of prior physical conditioning on relaxing response of corpus cavernosum from rats made hypertensive by nitric oxide inhibition (2007) (12)
- Neuroprotective action of melatonin on neonatal rat motoneurons after sciatic nerve transection [Brain Research 926 (2002) 33–41] (2002) (12)
- Nitric oxide release may be involved in the microcirculatory response to acetylcholine. (1990) (12)
- Long-term nitric oxide inhibition and chronotropic responses in rat isolated right atria. (1999) (12)
- Involvement of nitric oxide on the peritoneal neutrophil influx induced by staphylococcal enterotoxin B in mouse. (2001) (12)
- Modulation of eosinophil migration from bone marrow to lungs of allergic rats by nitric oxide. (2004) (12)
- Prevalence peptic lesion in asymptomatic, healthy volunteers (2001) (12)
- Clarithromycin bioequivalence study of two oral formulations in healthy human volunteers. (2000) (11)
- Comparative bioavailability of 4 amoxicillin formulations in healthy human volunteers after a single dose administration. (2001) (11)
- Phentolamine relaxes human corpus cavernosum by a nonadrenergic mechanism activating ATP-sensitive K+ channel (2005) (11)
- Release of eicosanoids from isolated lungs of guinea-pigs exposed to pure oxygen: effect of dexamtethasone. (1986) (11)
- Identification of a new vascular smooth muscle contracting polypeptide in Phoneutria nigriventer spider venom. (1993) (11)
- Quantification of cyproheptadine in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry in a bioequivalence study. (2012) (11)
- Contribution of C-fibers to leucocyte recruitment in bronchoalveolar lavage fluid and pleural cavity in the rat. (2001) (11)
- Comparative Bioavailability of Two Different Diclofenac Formulations in Healthy Volunteers (1999) (11)
- Role of cyclic GMP on inhibition by nitric oxide donors of human eosinophil chemotaxis in vitro (2004) (11)
- Comparative bioavailability of two cefadroxil formulations in healthy human volunteers after a single-dose administration. (2000) (11)
- QSAR models for inhibitors of physiological impact of Escherichia coli that leads to diarrhea. (2013) (11)
- Comparative Bioavailability Study with Two Gemfibrozil Tablet Formulations in Healthy Volunteers (2005) (11)
- Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results (2008) (11)
- The release of lyso-PAF from guinea-pig lungs. (1985) (11)
- The actions of endothelins−1 and −3 on the vascular and capsular smooth muscle of the isolated blood perfused spleen of the dog (1992) (10)
- 6-Nitrodopamine is released by human umbilical cord vessels and modulates vascular reactivity. (2021) (10)
- Role of Endothelin ETA and ETB Receptors in the Arterial Vasculature of the Isolated Canine Liver (1995) (10)
- Comparative bioavailability of two ramipril formulations after single-dose administration in healthy volunteers. (2006) (10)
- Immunohistochemical and functional characterization of nitric oxide signaling pathway in isolated aorta from Crotalus durissus terrificus. (2012) (10)
- Heparin, polycations, and atherosclerosis. (1993) (10)
- Comparative Bioavailability of Two Fluconazole Capsule Formulations in Healthy Volunteers (2000) (10)
- The kinetics of chondroitin 4-sulfate release from stimulated platelets and its relation to thromboxane A2 formation and granule secretion. (1994) (10)
- Electrical field stimulation-induced contractions on Pantherophis guttatus corpora cavernosa and aortae (2018) (9)
- Influence of Liposomal Local Anesthetics on Platelet Aggregation In Vitro (2004) (9)
- Dissociation between the increase in systemic vascular resistance induced by acute nitric oxide synthesis inhibition and the decrease in cardiac output in anesthetized dogs. (1997) (9)
- Vas deferens smooth muscle responses to the nitric oxide-independent soluble guanylate cyclase stimulator BAY 41-2272. (2012) (9)
- The effect of Phoneutria nigriventer (armed spider) venom on arterial blood pressure of anaesthetised rats. (1996) (9)
- Comparative bioavailability of three ibuprofen formulations in healthy human volunteers. (2008) (9)
- Design of Inhibitors for Human Tissue Kallikrein Using Non-Natural Aromatic and Basic Amino Acids (2002) (9)
- INHALED CORTICOSTEROIDS FOR RESPIRATORY DISTRESS? (1985) (9)
- Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension (2021) (9)
- A randomized double-blind, non-inferiority Phase II trial, comparing dapaconazole tosylate 2% cream with ketoconazole 2% cream in the treatment of Pityriasis versicolor (2015) (9)
- The role of heart rate in the modulation of the decreased cardiac output induced by acute nitric oxide synthesis inhibition in anaesthetized dogs. (1999) (9)
- Investigation of the haemodynamic effects of Phoneutria nigriventer venom in anaesthetised rabbits. (2000) (8)
- Modulation of coronary flow and cardiomyocyte size by sensory fibers. (1999) (8)
- Toward More GI-Friendly Anti-Inflammatory Medications (2015) (8)
- LOW-DOSE INHALED NITRIC OXIDE (NO) ATTENUATES HEMODYNAMIC CHANGES FOLLOWING ACUTE PULMONARY AIR EMBOLISM (PAE) IN DOGS (1998) (8)
- Pharmacokinetics of dihydroergocristine and its major metabolite 8'-hydroxy-dihydroergocristine in human plasma. (2005) (8)
- Electrical field stimulation induces endothelium-dependent contraction of human umbilical cord vessels. (2020) (8)
- Influence of physical preconditioning on the responsiveness of rat pulmonary artery after pulmonary ischemia/reperfusion. (2007) (8)
- A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry. (2005) (8)
- Influence of gastric acid secretion blockade and food intake on the bioavailability of a potassium diclofenac suspension in healthy male volunteers. (1996) (8)
- Rebamipide does not protect against naproxen-induced gastric damage: a randomized double-blind controlled trial (2016) (8)
- Pre-exposure to Staphylococcal enterotoxin A exacerbates the pulmonary allergic eosinophil recruitment in rats. (2010) (8)
- Relaxant effect of a metal-based drug in human corpora cavernosa and its mechanism of action (2016) (8)
- Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B. (2009) (8)
- Ciprofibrate quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry for pharmacokinetic studies. (2011) (8)
- Comparative bioavailability of single doses of tablet formulations of cetirizine dihydrochloride in healthy male volunteers. (1995) (8)
- Electrical field-induced contractions on Crotalus durissus terrificus and Bothrops jararaca aortae are caused by endothelium-derived catecholamine (2018) (8)
- Soluble Guanylate Cyclase Modulators, BAY 41-2272 and BAY 60-2770, Inhibit Human and Rabbit Prostate Contractility. (2016) (7)
- Modulation by endogenous prostanoids of the vasoconstrictor activity of endothelin‐1 in the canine isolated, perfused spleen (1994) (7)
- Comparative bioavailability of two suspension formulations of potassium diclofenac in healthy male volunteers. (1994) (7)
- Role of Ca2+ in vascular smooth muscle contractions induced by Phoneutria nigriventer spider venom. (2004) (7)
- Release of vasoactive substances from guinea pig isolated lungs perfused via the trachea. (1987) (7)
- Mechanism of pain induced by radiocontrast media. (1992) (7)
- Expression of neuronal isoform of nitric oxide synthase in spinal neurons of neonatal rats after sciatic nerve transection (2001) (7)
- PHARMACOKINETICS AND PHARMACODYNAMICS OF A NITRIC OXIDE‐RELEASING DERIVATIVE OF ENALAPRIL IN MALE BEAGLES (2007) (7)
- Mirabegron elicits rat corpus cavernosum relaxation and increases in vivo erectile response. (2019) (7)
- Comparison of the reactivity of micro-and macrovessels to noradrenaline and endothelin in rats with renal (2K1C) hypertension. (1990) (7)
- Pharmacological profile of Phoneutria nigriventer venom on rabbit vascular smooth muscle. (1990) (7)
- Determination of dopamine, noradrenaline and adrenaline in Krebs-Henseleit's solution by liquid chromatography coupled tandem mass spectrometry. Measurement of basal release from Chelonoidis carbonaria aortae in vitro. (2020) (7)
- Comparison of the survival of endothelium‐derived relaxing factor and nitric oxide within the isolated perfused mesenteric arterial bed of the rat (1989) (7)
- Quantification of dapaconazole in human plasma using high-performance liquid chromatography coupled to tandem mass spectrometry: application to a phase I study. (2014) (7)
- Quantification of 6-nitrodopamine in Krebs-Henseleit's solution by LC-MS/MS for the assessment of its basal release from Chelonoidis carbonaria aortae in vitro. (2021) (7)
- BETA-3 RECEPTOR AGONIST, MIRABEGRON RELAXES ISOLATED PROSTATE FROM HUMAN AND RABBIT: NEW THERAPEUTIC INDICATION (2014) (7)
- Pharmacokinetic and Pharmacodynamic Evaluation of a Nanotechnological Topical Formulation of Lidocaine/Prilocaine (Nanorap) in Healthy Volunteers (2015) (6)
- Acid suppression by omeprazole does not affect orally administered metronidazole bioavailability and metabolism in healthy male volunteers (1998) (6)
- Enhanced airways responsiveness in rats depleted of sensory neuropeptides by neonatal capsaicin treatment (2003) (6)
- Eicosanoids and skin. (1988) (6)
- Eicosanoid release by rectal mucosa in vitro in ulcerative colitis: effects of conventional and potential new therapies (1992) (6)
- The soluble guanylyl cyclase activator BAY 60-2770 inhibits murine allergic airways inflammation and human eosinophil chemotaxis. (2016) (6)
- Bioavailability of four pharmaceutical formulations of metronidazole tested on normal healthy volunteers. (1991) (6)
- 6-NitroDopamine is an endogenous modulator of rat heart chronotropism. (2022) (6)
- Different mechanisms underlie the effects of acute and long-term inhibition of nitric oxide synthases in antigen-induced pulmonary eosinophil recruitment in BALB/C mice. (2009) (6)
- Analysis of dihydropyridine calcium channel blockers using negative ion photoionization mass spectrometry. (2008) (6)
- Pharmacological and transcriptomic characterization of the nitric oxide pathway in aortic rings isolated from the tortoise Chelonoidis carbonaria. (2019) (6)
- 6-Nitrodopamine is an endogenous mediator of rat isolated epididymal vas deferens contractions induced by electric-field stimulation. (2021) (6)
- Endothelium‐derived dopamine modulates EFS‐induced contractions of human umbilical vessels (2020) (6)
- Comparative bioavailability of two sertraline tablet formulations in healthy human volunteers after a single dose administration. (1998) (6)
- Atmospheric pressure photoionization applied to quantitation of cyproterone acetate in human plasma. (2005) (6)
- Phase I Study Of The Novel Antifungal Agent Dapaconazole (zilt®) In Healthy Volunteers (2014) (6)
- Q817G mutation in phosphodiesterase type 5: Conformational analysis and dissociation profile of the inhibitor Tadalafil (2019) (6)
- Comparative bioavailability study with two pantoprazole delayed-released tablet formulations administered with and without food in healthy subjects. (2011) (6)
- Eicosanoids and skin. (1988) (6)
- Quantification of chlordesmethyldiazepam by liquid chromatography-tandem mass spectrometry: application to a cloxazolam bioequivalence study. (2009) (5)
- Amlodipine Reduces the Antimigratory Effect of Diclofenac in Spontaneously Hypertensive Rats (2008) (5)
- BAY 41-2272, a soluble guanylate cyclase stimulator, relaxes isolated human ureter in a standardized in vitro model. (2014) (5)
- Effects of beta-adrenoceptor antagonists in the neural nitric oxide release induced by electrical field stimulation and sodium channel activators in the rabbit corpus cavernosum. (2005) (5)
- Assessment of pharmacokinetic interaction between piracetam and l-carnitine in healthy subjects. (2016) (5)
- A Phase I clinical trial of lodenafil carbonate, a new phosphodiesterase Type 5 (PDE5) inhibitor, in healthy male volunteers. (2012) (5)
- Cholinergic regulation along the pulmonary arterial tree of the South American rattlesnake: vascular reactivity, muscarinic receptors, and vagal innervation. (2020) (5)
- The use of Healthy Volunteers to Evaluate Bioequivalence of AntineoplasicDrugs: Pilot Studies with Capecitabine (2011) (5)
- Short-term sucralfate administration alters potassium diclofenac absorption in healthy male volunteers. (1997) (5)
- Pharmacological characterization of the novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum (2007) (5)
- The rabbit vagina as an in vivo model for vaginal fenticonazole permeability and toxicity. (2018) (5)
- In vivo inhibition of nitric oxide synthesis does not depend on renin-angiotensin system activation. (1996) (5)
- Upregulation of muscarinic receptors by long‐term nitric oxide inhibition in the rat ileum (2003) (5)
- 6‐nitrodopamine is a major endogenous modulator of human vas deferens contractility (2022) (4)
- Characterisation of functional endothelin receptors in the canine isolated perfused spleen. (1995) (4)
- Chronotropic response of β-adrenergic-, muscarinic-, and calcitonin gene-related peptide-receptor agonists in right atria from neonatal capsaicin-treated rats (2002) (4)
- Release of 6-nitrodopamine modulates vascular reactivity of Pantherophis guttatus aortic rings. (2022) (4)
- Preparation and Local Anaesthetic Activity of Benzotriazinone and Benzoyltriazole Derivatives. (2000) (4)
- Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration (2019) (4)
- THU0464 PHASE 2 CLINICAL TRIAL OF THE GI SAFETY OF A HYDROGEN SULFIDE-RELEASING ANTI-INFLAMMATORY DRUG (ATB-346) (2019) (4)
- Pharmacokinetic Profile of Atenolol Aspirinate (2007) (4)
- Randomized, double‐blind, phase III clinical study of a novel nanotechnological topical anesthetic formulation containing lidocaine 25 mg/g and prilocaine 25 mg/g (nanorap) in skin phototypes I–III patients with ablative fractional CO2 laser treatment indication in the forehead (2019) (4)
- Short-term sucralfate administration does not alter the absorption of metronidazole in healthy male volunteers. (1996) (4)
- The effect of a 1-week administration of cetirizine on the chemotaxis and superoxide anion production of neutrophils from healthy volunteers. (1996) (4)
- Endothelium modulates electrical field stimulation-induced contractions of Chelonoidis carbonaria aortic rings. (2020) (4)
- Comparative bioavailability of two escitalopram formulations in healthy human volunteers. (2010) (4)
- Capecitabine bioequivalence in healthy volunteers. (2018) (4)
- Tolerability of 2.5% Lidocaine/Prilocaine Hydrogel in Children Undergoing Cryotherapy for Molluscum Contagiosum (2016) (4)
- Design of inhibitors for tissue kallikreins based on their extended binding site specificities (1995) (3)
- Bioequivalence evaluation of two roxithromycin formulations in healthy human volunteers by high performance liquid cromatography coupled to tandem mass spectrometry. (1999) (3)
- Pharmacological characterization of the presynaptic activity of Tityus serrulatus venom in the rat anococcygeus muscle. (2003) (3)
- Dapaconazole versus ketoconazole in the treatment of interdigital tinea pedis. (2017) (3)
- Pharmacokinetics and pharmacodynamics of three dosages of oestriol after continuous vaginal ring administration for 21 days in healthy, postmenopausal women (2018) (3)
- Bioequivalence study between a fixed-dose single-pill formulation of nebivolol plus hydrochlorothiazide and separate formulations in healthy subjects using high-performance liquid chromatography coupled to tandem mass spectrometry. (2017) (3)
- Cyclosporine bioequivalence study: quantification using fluorescence polarization immunoassay (FPIA) and radioimmunoassay (RIA). (2004) (3)
- Quantification of estradiol cypionate in plasma by liquid chromatography coupled with tandem mass spectrometry: Application in a pharmacokinetic study in healthy female volunteers (2019) (3)
- Bioequivalence of Two Lithium Formulations in Healthy Volunteers (2006) (3)
- β1- and β1/β2-adrenergic receptor antagonists block 6-nitrodopamine-induced contractions of the rat isolated epididymal vas deferens (2022) (3)
- Modulation of polycation-induced human platelet aggregation (1993) (3)
- Sensory Functions (2001) (3)
- 6-Nitrodopamine is an endogenous selective dopamine receptor antagonist in Chelonoidis carbonaria aorta. (2022) (3)
- Bioavailability of Different formulations of metformin hydrochloride in healthy volunteers : a comparative study (2016) (3)
- Quantification of 3α-hydroxytibolone in human plasma by high performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS): Application in a bioequivalence study in healthy postmenopausal volunteers (2016) (3)
- Physiologic Role of ETA Receptors in the Regulation of Renal Hemodynamics in Normal and Salt‐Depleted Rats (1995) (3)
- Post-prandial reabsorption of paracetamol (1994) (3)
- Acetylsalicylic Acid Daily vs Acetylsalicylic Acid Every 3 Days in Healthy Volunteers: Effect on Platelet Aggregation, Gastric Mucosa, and Prostaglandin E2 Synthesis (2016) (3)
- Phentolamine bioequivalence study. (2004) (3)
- Inhibition of heparin synthesis by methotrexate in rats in vivo. (2002) (3)
- PROTECTIVE EFFECT OF BAY 41-2272 (SGC STIMULATOR) ON HYPERTENSION AND HEART HYPERTROPHY INDUCED BY CHRONIC L-NAME TREATMENT IN RATS: OP 071 (2004) (3)
- Inhibitory effects of staphylococcal enterotoxin type B on human platelet adhesion in vitro (2008) (3)
- Pharmacological characterization of novel tissue kallikrein inhibitors in vivo. (1996) (3)
- Propylthiouracil quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry: application in a bioequivalence study. (2014) (3)
- Experimental Models of Pulmonary and Joint Inflammation and Their Relevance to Man (1988) (2)
- In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives. (2006) (2)
- Administration of BAY 41-2272 prevents bladder dysfunction in nitric-oxide deficient rats. (2010) (2)
- INHALED NITRIC OXIDE (NO) IMPROVES HEMODYNAMICS DURING A VENOUS AIR INFUSION (VAI) IN DOGS (1998) (2)
- Relaxant effect of BAY 41–2272 in the rabbit isolated detrusor smooth muscle (DSM): involvement of cGMP-independent mechanisms (2007) (2)
- Hydrochlorothiazide Potentiates Contractile Activity of Mouse Cavernosal Smooth Muscle (2016) (2)
- Effects Of Indomethacin On Endothelin-1 Evoked Vasoconstriction And Release Of Eicosanoids From The Isolated, Perfused, Canine Spleen (1993) (2)
- Comparative bioavailability of two zolpidem hemitartrate formulations in healthy human Brazilian volunteers using high-performance liquid chromatography coupled to tandem mass spectrometry. (2020) (2)
- P.44 INTRA-INDIVIDUAL REPRODUCIBILITY OF THE GLUCOSE HYDROGEN BREATH TEST IN A COHORT OF HEALTHY SUBJECTS (2010) (2)
- Pharmacokinetics of Riluzole in Beagle Dogs (2018) (2)
- The effects and molar potency of iloprost, U46619 and sodium nitroprusside on capsular and vascular smooth muscle of the isolated perfused canine spleen. (1994) (2)
- Pharmacokinetics of dapaconazole, a novel antifungal agent, in beagle dogs and inhibition of cytochrome P450 family 51 (2017) (2)
- Laser Therapy and Muscle Fatigue: A Promising Research Area. (2016) (2)
- Abuse liability of intra-nasal midazolam in inhaled-cocaine abusers (2008) (2)
- MP-12.11: Pharmacological characterization of the novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum (2007) (2)
- Amiloride Relaxes Rat Corpus Cavernosum Relaxation In Vitro and Increases Intracavernous Pressure In Vivo. (2019) (2)
- The basal release of endothelium-derived catecholamines regulates the contractions of Chelonoidis carbonaria aorta caused by electrical-field stimulation (2020) (2)
- Simultaneous quantification of cyclosporin, tacrolimus, sirolimus and everolimus in whole blood by UHPLC-MS/MS for therapeutic drug monitoring. (2021) (2)
- A bioequivalence study of citalopram based on quantification by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. (2005) (2)
- Single-dose pharmacokinetics and pharmacodynamics assessment of oestriol and trimegestone containing vaginal rings in healthy women with childbearing potential (2021) (2)
- Comparative Bioavailability Study with Two Amiodarone Tablet Formulations Administered with and without Food in Healthy Subjects (2007) (2)
- Involvement of nitric oxide in the smooth muscle tone of the isolated canine spleen and the responses to acetylcholine and substance P. (1996) (2)
- Comparison of dapaconazole with miconazole in the treatment of Tinea cruris (2018) (2)
- Plasma hydroxy metronidazole/metronidazole ratio in anti-HCV carriers with and without apparent liver disease. (1998) (2)
- Bioavailability study of two 81-mg coated tablet formulations of acetylsalicylic acid in fed healthy subjects . (2020) (2)
- Metal-organic framework (MOF) nanomedicine preparations of sildenafil designed for the future treatment of pulmonary arterial hypertension (2019) (2)
- Pharmacokinetic profile of two different pharmaceutical forms of theophylline (a slow release tablet and a syrup) after multiple dose administration to healthy human volunteers. (1993) (1)
- A3 A PROOF-OF-CONCEPT, PHASE 2 CLINICAL TRIAL OF THE GI SAFETY OF A HYDROGEN SULFIDE-RELEASING ANTI-INFLAMMATORY DRUG (ATB-346) (2019) (1)
- Investigation on the positive chronotropic action of 6-nitrodopamine in the rat isolated atria. (2023) (1)
- Determination of RSD921 in human plasma by high-performance liquid chromatography-tandem mass spectrometry using tri-deuterated RSD921 as internal standard: application to a phase I clinical trial. (2001) (1)
- Exercise training effects on vascular reactivity and metabolic parameters of high caloric-fed Wistar rats (2007) (1)
- COMPARATIVE BIOAVAILABILITY OF TWO CAPSULE FORMULATIONS OF OFLOXACIN IN HEALTHY VOLUNTEERS AFTER A SINGLE DOSE ADMINISTRATION (1999) (1)
- Prospective Prediction of Dapaconazole Clinical Drug–Drug Interactions Using an In Vitro to In Vivo Extrapolation Equation and PBPK Modeling (2022) (1)
- Comparative bioavailability of cefuroxime axetil suspension formulations administered with food in healthy subjects (2010) (1)
- Evaluation of the mutagenic potential of a new antiinflamatory drug using Ames Test (2003) (1)
- Quantification of cyclic AMP and cyclic GMP levels in Krebs-Henseleit solution by LC-MS/MS: Application in washed platelet aggregation samples. (2022) (1)
- Synthesis of phenylpyrimidinones as guanylyl cyclase C inhibitors. (2019) (1)
- Neutrophil chemotaxis in vitro induced by chemoattract agents in control and capsaicin treated rats (2002) (1)
- Determination of RSD 921 in human plasma by high-performance liquid chromatography – tandem mass spectrometry using tri-deuterated RSD 921 as internal standard : application to a phase I clinical trial (2001) (1)
- INHALEd nebulised unfractionated HEParin for the treatment of hospitalised patients with COVID-19 (INHALE-HEP): Protocol and Statistical Analysis Plan for an investigator-initiated international meta-trial of randomised studies (2020) (1)
- Protective effect of BAY 41-2272 (sGC stimulator) on hypertension and heart hypertrophy induced by chronic L-NAME treatment in rats (2003) (1)
- Hydroxocobalamin quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a pharmacokinetic study (2013) (1)
- The soluble guanylyl cyclase activator BAY 60-2770 ameliorates detrusor dysfunction in obese mice (2013) (1)
- The inhibition of thrombin-induced human platelet aggregation by proteins present in serum from the opossum Didelphis albiventris (1992) (1)
- Anti-inflammatory activities of Ph CL28A in rats in vivo. (1993) (1)
- Quantification of mycophenolic acid in human plasma by liquid chromatography with time-of-flight mass-spectrometry for therapeutic drug monitoring. (2020) (1)
- Role of adenosine triphosphate-dependent potassium channels in canine penile erection. (2004) (1)
- The effect of glucocorticoids on lyso-PAF formationin vitro andin vivo (2005) (1)
- In vitro metabolism of the new antifungal dapaconazole using liver microsomes. (2022) (1)
- Ethanol reduces the endothelin-B receptor-mediated increase in portal inflow resistance in the isolated, perfused canine liver. (1998) (1)
- The basal release of endothelium-derived catecholamines regulates the contractions of Chelonoidis carbonaria aorta caused by electrical-field stimulation. (2020) (1)
- Bioequivalence Study of Three Ascorbic Acid Tablet Formulations in Healthy Male Volunteers (1998) (1)
- Effect of the Physical Training on the Vascular Responsiveness after Pulmonary Ischemia/Reperfusion in Rat: 9:45AM–10:00AM (2006) (0)
- Physical activity and chronotropic response in isolated right atria in hypertensive rats. (1998) (0)
- Genitourinary dysfunctions associated with heart failure in model of chronic volume overload in rats (2012) (0)
- Effect of chronic inhibition of nitric oxide (NO) synthesis on bone marrow eosinophils (1998) (0)
- Nitric oxide - releasing compounds fail to increase cgmp levels in chinese hamster lung fibroblasts (1996) (0)
- INHALEd nebulised unfractionated HEParin for the treatment of hospitalised patients with COVID-19 (INHALE-HEP): Protocol for an investigator-initiated international meta-trial of randomised studies (2020) (0)
- Effect of physical preconditioning on erectile response of rats made hypertensive by Ng-nitro-L-arginine methyl ester treatment (2005) (0)
- 6-Nitrodopamine potentiates contractions of rat isolated vas deferens induced by noradrenaline, adrenaline, dopamine and electric field stimulation. (2023) (0)
- Effect of new sildenafil analogues in the rabbit isolated aorta (2007) (0)
- Immunohistochemical detection of tyrosine hydroxylase in human corpus cavernosum endothelial cells (2020) (0)
- Smooth muscle reactivity of corpus cavernosum (CC) and anococcygeus muscle (AcM) from rats with experimental allergic encephalomyelitis (EAE) (2003) (0)
- Comparative Study of Sildenafil Analogues in the Rabbit Isolated Aorta (2006) (0)
- The soluble guanylyl cyclase activator BAY 60-2770 ameliorates detrusor dysfunction in obese mice (2013) (0)
- THE RENIN-ANGIOTENSIN SYSTEM (RAS) PLAYS A MAJOR ROLE IN THE VOIDING DYSFUNCTION OF OVARIECTOMIZED RATS (2013) (0)
- OC.11.2 EXPRESSION OF INTERLEUKIN IL-13 RECEPTOR IN HELICOBACTER PYLORI-RELATED GASTRIC DISEASES (2010) (0)
- Comparative Bioavailability Study with Two Chlorpropamide Tablet Formulations in Healthy Volunteers (2007) (0)
- Effect of chronic treatment with nitric oxide inhibitor L-name on eosinophilic migration in a murine model of asthma (2005) (0)
- Contractile response of rat isolated detrusor smooth muscle for carbachol after long-term L-NAME-treatment (2004) (0)
- The effect of crotapotin on carrageenin-induced rat hind-paw oedema (1996) (0)
- NITRIC OXIDE MODULATES THE EOSINOPHIL INFILTRATION IN ANTIGEN-INDUCED AIRWAY INFLAMMATION IN RATS (1997) (0)
- Improvement of vascular reactivity by propranolol in hypertension induced by prolonged nitric oxide blockade (2005) (0)
- Oral Bioavailability of Deuterated L‐carnitine in Healthy Volunteers (2021) (0)
- Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol (2022) (0)
- Influence of prenatal dexamethasone administration in allergic adult male rats (2003) (0)
- Full Paper Pharmacokinetic Profile of Atenolol Aspirinate (2007) (0)
- Additional file 2: Table S2. of Rebamipide does not protect against naproxen-induced gastric damage: a randomized double-blind controlled trial (2016) (0)
- Evaluation of folic acid supplementation by concomitant administration of ethinyl estradiol + levonorgestrel in healthy female subjects . (2019) (0)
- Effect of chronic blockade of nitric oxide synthesis on pmn infiltration of sensitized rat lungs (1996) (0)
- Effect of recombinant human interferon gamma therapy on nitric oxide release by neutrophils and mononuclear cells from patients (1994) (0)
- 6-Nitrodopamine is the Most Potent Endogenous Positive Inotropic Agent in the Rat Isolated Heart (2022) (0)
- Loss of BNOS-immunoreactive neurons and synaptic plasticity in the human epileptic hippocampus (1997) (0)
- Mechanisms of relaxant activity of BAY 41-2272 in rat tracheal smooth muscle in vitro (2009) (0)
- Relaxation of thoracic aorta and pulmonary artery rings of marmosets (Callithrix spp.) by endothelium-derived 6-nitrodopamine (2023) (0)
- Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP (vasopressinyL-nitroarginine methyl esterynitric oxideyNO synthaseyNO synthase immunocytochemistry) (1999) (0)
- Leucocyte migration induced by phospholipases 'A IND.2' homologues: dissociation between enzymatic and biological activity (1996) (0)
- pharmaceutical composition comprising excipients farmacologiamente active products in which the excipients are based vitamin e, papain and hyaluronidase. (2001) (0)
- PIII‐80 (2006) (0)
- Physiologic role of endothelin on regulation of renal and systemic hemodynamics in the rat (1994) (0)
- Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti‐Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation (2019) (0)
- In Silico Mapping of Essential Residues in the Catalytic Domain of PDE5 Responsible for Stabilization of Its Commercial Inhibitors (2019) (0)
- Run training ameliorates the established erectile dysfunction in rats under long-term nitric oxide (NO) blockade (2007) (0)
- Effect of coli LPS on platelet adhesion to collagen (2003) (0)
- Nitrergic relaxation of rabbit corpus cavernosum induced by batrachotoxin (2002) (0)
- Basic and Translational Science ncreased Cyclic Guanosine Monophosphate ynthesis and Calcium Entry Blockade ccount for the Relaxant Activity of the itric Oxide–Independent Soluble Guanylyl yclase Stimulator BAY 41-2272 in the abbit Penile Urethra (2008) (0)
- Oedema formation and mast cell degranulation induced by bothropstoxin i and ii in rat (1995) (0)
- 499 Effect of norbornene derivative in corpus cavernosum relaxation, as 5-HT1A agonist and 5-HT2A antagonist (2018) (0)
- Supersensitivity of rat ileum to methacholine in animals with chronic blockade of nitric oxide (NO). (1999) (0)
- Lack of correlation between nitrotyrosine (NT) -modified protein expression, superoxide anion SUP and nitric oxide (NO) production in endotoxemic rats (2002) (0)
- Release of a nitric oxide-like factor from rat islets of langerhans (1992) (0)
- Participation of sensory nerve fibers in the modulation of cardiac functions in response to beta-, muscarinic-, and CGRP-agonists (1999) (0)
- AMILORIDE INDUCES CHANGES IN RAT CAVERNOSAL SMOOTH MUSCLE REACTIVITY (2011) (0)
- Clinical toxicology study of a herbal medicinal extract of Aconitum na- pellus, Nasturtium officinale, Myroxylon balsamum, Mikania glomerata, Cephaelis ipecacuanha and Polygala senega (Melagrião®) in healthy vol- unteers (2010) (0)
- Expression of nitric oxide synthase (NOS) isoforms in the chronic NOS inhibition model: effect of dietary salt (1999) (0)
- EFFECT OF DILTIAZEM ON ARTERIAL HYPERTENSION AND MYOCARDIAL ISCHAEMIA INDUCED BY CHRONIC INHIBITION OF NITRIC OXIDE (NO) SYNTHESIS (1997) (0)
- Endogenous inhibitory activity of nitric oxide synthase (NOS) in diabetic rats (2003) (0)
- The inotropic and chronotropic response in isolated right atria and whole heart in capsaicin-treated (1998) (0)
- A high-throughput method for determining chloramphenicol residues in poultry, egg, shrimp, fish, swine and bovine using LC-ESI-MS/MS (2009) (0)
- Propafenone quantification in human plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry in a bioequivalence study . (2018) (0)
- Potency of muscarinic agonists in isolated right atria from L-NAME-treated rats. (1998) (0)
- Effect of crotapotin on the acute inflammatory response induced by phospholipase A2 from different sources (1996) (0)
- Plasma hydroxy metronidazole/metronidazole ratio in anti-HCV carriers with and without apparent liver disease (1998) (0)
- Thanks to reviewers (2019) (0)
- β1- and β1/β2-adrenergic receptor antagonists block 6-nitrodopamine-induced contractions of the rat isolated epididymal vas deferens (2022) (0)
- Haemodynamic changes caused by inhalation of nitric oxide (NO) in dogs under normoxia and hyperoxia (1998) (0)
- PD62-12 6-NITRODOPAMINE IS RELEASED BY RAT ISOLATED VAS DEFERENS AND MODULATES ITS CONTRACTILITY (2021) (0)
- Pharmacodynamic evaluation of L-carnitine and piracetam in muscle injury induced by the chronic use of simvastatin . (2020) (0)
- Effect of Physical Preconditioning on Vascular Reactivity and Metabolic Parameters of Wistar Rats Treated with Cafeteria Diet: 10:00AM–10:15AM (2006) (0)
- Determination of captopril by hplctandem mass spectrometry: application in a bioequivalence study (2012) (0)
- Hypertension induce by chronic no synthesis blockade is not related to the induction of tissular ace activity but is prevented by enalapril (1996) (0)
- Arterial hypertension induced by nitric oxide (NO) inhibition. Potency of beta- and muscarinic-agonists in rat isolated right atria. (1999) (0)
- Characterization of erectile dysfunction and overactive bladder in heart failure rats: model of volume overload (837.6) (2014) (0)
- Clinical toxicology study of Melagrião in healthy volunteers (2010) (0)
- Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of rattlesnake corpus cavernosum (2011) (0)
- Plasma hydroxy-metronidazole ratio in ethanol abusers (1998) (0)
- Molecular pathways and interleukin (IL)-13 role in the modulation of inflammatory response during H. pylori infection (2006) (0)
- Arterial hypertension induced by nitric oxide inhibition: Potency of beta agonists in rat right atria. (1998) (0)
- Immunohistochemical detection of neuronal nitric oxide synthase (nNOS) in human nervous tissue and PC12 cells culture (2002) (0)
- Blood pressure and erectile response in long-term NG-Nitro-L-arginine Methyl Ester treated rats submitted to treadmill training. (2004) (0)
- 2055 MECHANISMS OF RELAXANT ACTIVITY OF THE NITRIC OXIDE-INDEPENDENT SOLUBLE GUANYLYL CYCLASE STIMULATOR BAY 41-2272 IN ISOLATED HUMAN URETER: AN IN VITRO STUDY (2011) (0)
- Alteration in contractile mechanism of rat cavernosal smooth muscle induced by different class‐diuretics (2010) (0)
- Effects of chronic nitric oxide inhibition on the potency of 'alpha' and 'beta' agonists in isolated tissue from rats (1997) (0)
- Mechanisms underlying the relaxation of rat mesenteric bed by beta-adrenoceptor blockers (2004) (0)
- Effect of Treadmill Training in the Erectile Function of Rats Submitted to Cafeteria Diet. (2006) (0)
- Characterization of endothelin receptors in isolated, perfused human spleen. (1998) (0)
- Erectile Dysfunction and the Endothelium (2018) (0)
- Secretory 'PLA IND.2' from naja mossambica mossambica venom induces acute pancreatitis and lung injury in rats (2003) (0)
- Vascular reactivity to propanolol in rat mesenteric bed and aorta (2003) (0)
- Comparative bioavailability study with two sodium valproate tablet formulations administered under fasting conditions in healthy subjects. (2022) (0)
- Inhibitory effects of Allium sp on platelet activity in vitro and in vivo (2001) (0)
- Role of a novel tetrodotoxin-resistant sodium channel in the nitrergic relaxation of rattlesnake corpus cavernosum (2011) (0)
- Supersensitivity of muscarinic receptors in rat isolated detrusor smooth muscle (DSM) after chronic nitric oxide inhibition (2007) (0)
- P110. Effect of the physical training on the vascular responsiveness of rat mesenteric artery after pulmonary ischemia reperfusion (2006) (0)
- Ethanol alters ETB receptor-mediated responses in the canine liver, but not in the rat stomach (1998) (0)
- OC.07.5 HCV-ANTIVIRAL THERAPY DELAYS GASTRIC EMPTYING TIME AND MODIFIES CCK AND MOTILIN SERUM LEVELS (2012) (0)
- P.125 13C-AMINOPYRINE BREATH TEST PREDICTS THE CLINICAL OUTCOME IN PATIENTS WITH C VIRUS-RELATED CHRONIC HEPATITIS (2010) (0)
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