Gilla Kaplan
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Philosophy Biology
Gilla Kaplan's Degrees
- PhD Immunology University of California, San Francisco
- Doctorate Medicine Stanford University
Why Is Gilla Kaplan Influential?
(Suggest an Edit or Addition)Gilla Kaplan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes (1991) (1215)
- Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation (1993) (1038)
- Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. (1999) (770)
- A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response (2004) (710)
- Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-α/β (2001) (600)
- Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens (2008) (594)
- Thalidomide Costimulates Primary Human T Lymphocytes, Preferentially Inducing Proliferation, Cytokine Production, and Cytotoxic Responses in the CD8+ Subset (1998) (580)
- Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin (1994) (572)
- Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro (1979) (502)
- Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism (2010) (400)
- Metformin as adjunct antituberculosis therapy (2014) (396)
- Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns. (2010) (384)
- The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice (2003) (363)
- Human dendritic cells. Enrichment and characterization from peripheral blood (1982) (360)
- Mycobacterium tuberculosis Growth at theCavity Surface: a Microenvironment with FailedImmunity (2003) (355)
- Functional Capacity of Mycobacterium tuberculosis-Specific T Cell Responses in Humans Is Associated with Mycobacterial Load (2011) (322)
- Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates. (1999) (320)
- Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. (1986) (315)
- Amino-substituted thalidomide analogs: Potent inhibitors of TNF-α production (1999) (308)
- The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro (2007) (305)
- Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway. (2005) (292)
- Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing (1992) (278)
- The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin (1987) (274)
- Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients (2003) (273)
- Interleukin-10 (IL-10) in Experimental Visceral Leishmaniasis and IL-10 Receptor Blockade as Immunotherapy (2002) (268)
- Thalidomide Treatment Reduces Tumor Necrosis Factor α Production and Enhances Weight Gain in Patients with Pulmonary Tuberculosis (1995) (266)
- Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control. (2007) (262)
- Mycobacterium tuberculosis Catalase and Peroxidase Activities and Resistance to Oxidative Killing in Human Monocytes In Vitro (1999) (259)
- Virulence of selected Mycobacterium tuberculosis clinical isolates in the rabbit model of meningitis is dependent on phenolic glycolipid produced by the bacilli. (2005) (248)
- Differential Monocyte Activation Underlies Strain-Specific Mycobacterium tuberculosis Pathogenesis (2004) (236)
- In vitro differentiation of human monocytes. Differences in monocyte phenotypes induced by cultivation on glass or on collagen (1982) (234)
- Differences in the Mode of Phagocytosis with Fc and C3 Receptors in Macrophages (1977) (230)
- Thalidomide inhibits the replication of human immunodeficiency virus type 1. (1993) (227)
- Macrophages in tuberculosis: friend or foe (2013) (222)
- Arachidonic acid metabolism by human monocytes. Studies with platelet- depleted cultures (1983) (221)
- Staphylococcus aureus RN6390 Replicates and Induces Apoptosis in a Pulmonary Epithelial Cell Line (2000) (211)
- Immunopathologic Effects of Tumor Necrosis Factor Alpha in Murine Mycobacterial Infection Are Dose Dependent (2000) (208)
- Bacillus Calmette-Guérin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles1 (2008) (178)
- The Cutaneous Infiltrates of Leprosy (1982) (176)
- Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies. (2004) (176)
- A new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers. (2008) (174)
- Keratinocyte growth regulation by the products of immune cells (1988) (172)
- Tumor necrosis factor α is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system (1999) (162)
- Prolonged treatment with recombinant interferon gamma induces erythema nodosum leprosum in lepromatous leprosy patients (1992) (161)
- The effect of thalidomide on the pathogenesis of human immunodeficiency virus type 1 and M. tuberculosis infection. (1996) (160)
- Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice (1997) (159)
- Immunity to intracellular bacteria. (1996) (159)
- TNF-α Controls Intracellular Mycobacterial Growth by Both Inducible Nitric Oxide Synthase-Dependent and Inducible Nitric Oxide Synthase-Independent Pathways1 (2001) (158)
- Structural modifications of thalidomide produce analogs with enhanced tumor necrosis factor inhibitory activity. (1996) (158)
- Survival of Mycobacterium avium andMycobacterium tuberculosis in Acidified Vacuoles of Murine Macrophages (1999) (156)
- Salmonid macrophages: separation, in vitro culture and characterization (1981) (155)
- Selection of Novel Analogs of Thalidomide with Enhanced Tumor Necrosis Factor α Inhibitory Activity (1996) (155)
- The Role of MmpL8 in Sulfatide Biogenesis and Virulence of Mycobacterium tuberculosis* (2004) (153)
- Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling (2010) (145)
- A combination of thalidomide plus antibiotics protects rabbits from mycobacterial meningitis-associated death. (1998) (145)
- Human TLR1 Deficiency Is Associated with Impaired Mycobacterial Signaling and Protection from Leprosy Reversal Reaction (2008) (142)
- Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy. (2008) (137)
- The Phenolic Glycolipid of Mycobacterium tuberculosis Differentially Modulates the Early Host Cytokine Response but Does Not in Itself Confer Hypervirulence (2008) (137)
- Selective increase in plasma tumor necrosis factor-alpha and concomitant clinical deterioration after initiating therapy in patients with severe tuberculosis. (1998) (136)
- The effect of bacille Calmette-Guérin vaccine strain and route of administration on induced immune responses in vaccinated infants. (2006) (134)
- Macrophage activation in vivo and in vitro. (1977) (129)
- Identification of immunostimulatory dendritic cells in the synovial effusions of patients with rheumatoid arthritis. (1985) (127)
- Mycobacterium tuberculosis inhibits maturation of human monocyte-derived dendritic cells in vitro. (2003) (126)
- The distinctive features of influenza virus infection of dendritic cells. (1998) (125)
- Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production. (1999) (123)
- Antibody Profiles Characteristic of Mycobacterium tuberculosis Infection State (2005) (122)
- Induction of ER Stress in Macrophages of Tuberculosis Granulomas (2010) (121)
- GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo. (1994) (118)
- Adjunctive Thalidomide Therapy for Childhood Tuberculous Meningitis: Results of a Randomized Study (2004) (116)
- Thalidomide as an anti-TNF-α inhibitor: Implications for clinical use (1996) (115)
- Rainbow trout macrophages in vitro: morphology and phagocytic activity. (1982) (112)
- Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis (2013) (110)
- Longitudinal changes in CD4(+) T-cell memory responses induced by BCG vaccination of newborns. (2013) (109)
- Mycobacterium leprae antigen-induced suppression of T cell proliferation in vitro. (1987) (108)
- Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2 (1983) (107)
- Role of activated macrophages in antibody-dependent lysis of tumor cells (1980) (104)
- Analysis of naturally occurring delayed-type hypersensitivity reactions in leprosy by in situ hybridization (1989) (103)
- Cytokine gene activation and modified responsiveness to interleukin-2 in the blood of tuberculosis patients. (1993) (103)
- Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro. (2003) (103)
- The reconstitution of cell-mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin 2 (1989) (100)
- Mycobacterial Antigens Exacerbate Disease Manifestations in Mycobacterium tuberculosis-Infected Mice (2002) (100)
- Thalidomide for the treatment of AIDS-associated wasting. (2000) (97)
- The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. (1982) (95)
- Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response (2011) (93)
- Transmission of tuberculosis in a South African community with a high prevalence of HIV infection. (2015) (93)
- Effect of cytokine modulation by thalidomide on the granulomatous response in murine tuberculosis. (1997) (92)
- Distribution and turnover of Langerhans cells during delayed immune responses in human skin (1987) (91)
- Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states. (2010) (91)
- Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction. (1988) (90)
- HIV-1 infection in infants severely impairs the immune response induced by Bacille Calmette-Guérin vaccine. (2009) (90)
- H2O2 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes (1996) (89)
- The systemic influence of recombinant interleukin 2 on the manifestations of lepromatous leprosy (1991) (89)
- Thalidomide stimulates T cell responses and interleukin 12 production in HIV-infected patients. (1999) (89)
- The wide utility of rabbits as models of human diseases (2018) (87)
- The metabolic and immunologic effects of short-term thalidomide treatment of patients infected with the human immunodeficiency virus. (1997) (87)
- Association of Human TLR1 and TLR6 Deficiency with Altered Immune Responses to BCG Vaccination in South African Infants (2011) (87)
- Effect of Standard Tuberculosis Treatment on Plasma Cytokine Levels in Patients with Active Pulmonary Tuberculosis (2012) (85)
- rhuIL-2 adjunctive therapy in multidrug resistant tuberculosis: a comparison of two treatment regimens and placebo. (1997) (85)
- Genetic polymorphism in Mycobacterium tuberculosis isolates from patients with chronic multidrug-resistant tuberculosis. (2004) (85)
- Plasma Cytokines, Cytokine Antagonists, and Disease Progression in African Women Infected with HIV-1 (1996) (84)
- Thalidomide and a Thalidomide Analogue Inhibit Endothelial Cell Proliferation in vitro (1999) (84)
- Bacillus Calmette Guerin Vaccination of Human Newborns Induces a Specific, Functional CD8+ T Cell Response1 (2006) (83)
- Prolonged immunostimulatory effect of low-dose polyethylene glycol interleukin 2 in patients with human immunodeficiency virus type 1 infection (1993) (82)
- Strong human immunodeficiency virus (HIV)-specific CD4+ T cell responses in a cohort of chronically infected patients are associated with interruptions in anti-HIV chemotherapy. (2000) (81)
- An analysis of in vitro T cell responsiveness in lepromatous leprosy (1985) (80)
- Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology. (2011) (80)
- Phosphodiesterase-4 Inhibition Alters Gene Expression and Improves Isoniazid – Mediated Clearance of Mycobacterium tuberculosis in Rabbit Lungs (2011) (80)
- Thalidomide and thalidomide analogs reduce HIV type 1 replication in human macrophages in vitro. (1997) (78)
- Innate Immune Response to Mycobacterium tuberculosis Beijing and Other Genotypes (2010) (77)
- In vitro differentiation of human monocytes. Monocytes cultured on glass are cytotoxic to tumor cells but monocytes cultured on collagen are not (1983) (77)
- Polymorphisms in Toll-like receptor 4 (TLR4) are associated with protection against leprosy (2009) (77)
- Evaluation of the Mtb72F Polyprotein Vaccine in a Rabbit Model of Tuberculous Meningitis (2006) (77)
- The selective binding and transmigration of monocytes through the junctional complexes of human endothelium (1988) (76)
- Ribonucleotide Reduction in Mycobacterium tuberculosis: Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases (2003) (75)
- Cellular immune response to Mycobacterium leprae infection in human immunodeficiency virus-infected individuals (1995) (75)
- Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement. (2002) (73)
- On the mechanism of internalization of opsonized particles by rat Kupffer cells in vitro. (1976) (72)
- Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits (2013) (70)
- Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages (2012) (70)
- Cellular responses to the intradermal injection of recombinant human gamma-interferon in lepromatous leprosy patients. (1987) (69)
- Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study (2015) (69)
- Phosphodiesterase 4 Inhibition Reduces Innate Immunity and Improves Isoniazid Clearance of Mycobacterium tuberculosis in the Lungs of Infected Mice (2011) (69)
- Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes. (2010) (68)
- The generation of antigen-specific, major histocompatibility complex- restricted cytotoxic T lymphocytes of the CD4+ phenotype. Enhancement by the cutaneous administration of interleukin 2 (1989) (67)
- Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system. (1999) (65)
- Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South African township. (2010) (64)
- Comparable growth of virulent and avirulent Mycobacterium tuberculosis in human macrophages in vitro. (1996) (64)
- BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease. (2007) (63)
- Advances in immunotherapy for tuberculosis treatment. (2009) (63)
- Characterization of the Divergent Wound-Healing Responses Occurring in the Pathergy Reaction and Normal Healthy Volunteers1 (2006) (62)
- Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation. (2005) (62)
- Thalidomide-induced antigen-specific immune stimulation in patients with human immunodeficiency virus type 1 and tuberculosis. (2000) (62)
- A metabolic biosignature of early response to anti-tuberculosis treatment (2014) (62)
- Translational Research for Tuberculosis Elimination: Priorities, Challenges, and Actions (2016) (61)
- The role of cytokines in the immune response to tuberculosis. (1996) (61)
- Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalence. (2009) (61)
- Use of IMiD3, a Thalidomide Analog, as an Adjunct to Therapy for Experimental Tuberculous Meningitis (2002) (61)
- Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Mycobacterium smegmatis-Induced Cytokine Production by Human Macrophages In Vitro (2001) (59)
- In vivo phenotypic dominance in mouse mixed infections with Mycobacterium tuberculosis clinical isolates. (2005) (58)
- Mycobacterium leprae Inhibits Dendritic Cell Activation and Maturation1 (2007) (58)
- Mycobacterial growth and sensitivity to H2O2 killing in human monocytes in vitro (1997) (58)
- Recognition and destruction of Bacillus Calmette-Guerin-infected human monocytes (1993) (57)
- Adjunctive Thalidomide Therapy of Childhood Tuberculous Meningitis: Possible Anti-Inflammatory Role (2000) (57)
- Cutaneous leishmaniasis. The defect in T cell influx in BALB/c mice (1987) (56)
- Influence of delayed immune reactions on human epidermal keratinocytes. (1986) (56)
- Role of the DinB Homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis (2010) (56)
- Immune stimulation in scleroderma patients treated with thalidomide. (2000) (55)
- Effect of multiple interferon gamma injections on the disposal of Mycobacterium leprae. (1989) (55)
- Sequestration of Mycobacterium tuberculosis in tight vacuoles in vivo in lung macrophages of mice infected by the respiratory route (1997) (55)
- Cytokine regulation of disease progression in leprosy and tuberculosis. (1994) (55)
- Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis (2012) (54)
- Thalidomide protects mice against LPS-induced shock. (1997) (52)
- Adverse reactions to thalidomide in patients infected with human immunodeficiency virus. (1997) (52)
- Qualification of a whole blood intracellular cytokine staining assay to measure mycobacteria-specific CD4 and CD8 T cell immunity by flow cytometry. (2015) (52)
- Efficacy of low doses of the polyethylene glycol derivative of interleukin-2 in modulating the immune response of patients with human immunodeficiency virus type 1 infection. (1993) (51)
- HIV-M. Leprae Interaction: Can HAART Modify the Course of Leprosy? (2008) (50)
- Aerosol infection of mice with recombinant BCG secreting murine IFN-gamma partially reconstitutes local protective immunity. (2000) (50)
- Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro. (2006) (50)
- Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model (2016) (49)
- Suppression of T-cell proliferation by Mycobacterium leprae and its products: the role of lipopolysaccharide. (1990) (49)
- ‘ZS-MDR-TB' versus ‘ZR-MDR-TB': improving treatment of MDR-TB by identifying pyrazinamide susceptibility (2012) (47)
- Long-term dominance of Mycobacterium tuberculosis Uganda family in peri-urban Kampala-Uganda is not associated with cavitary disease (2013) (46)
- Human newborn bacille Calmette–Guérin vaccination and risk of tuberculosis disease: a case-control study (2016) (46)
- Recombinant cytokines for controlling mycobacterial infections. (1995) (46)
- Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria (2008) (46)
- Mycobacterium leprae Actively Modulates the Cytokine Response in Naïve Human Monocytes (2009) (46)
- The nature and kinetics of a delayed immune response to purified protein derivative of tuberculin in the skin of lepromatous leprosy patients (1988) (41)
- Lessons of leprosy: the emergence of TH17 cytokines during type II reactions (ENL) is teaching us about T-cell plasticity. (2012) (40)
- Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth (2009) (38)
- Rational Immunotherapy with Interleukin 2 (1992) (38)
- Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis. (2017) (38)
- Host Targeted Activity of Pyrazinamide in Mycobacterium tuberculosis Infection (2013) (37)
- Administration of recombinant interleukin-2 reduces the local parasite load of patients with disseminated cutaneous leishmaniasis. (1990) (37)
- Recent advances in cytokine therapy in leprosy. (1993) (37)
- Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis (2013) (37)
- Effect of recombinant interferon-gamma on hydrogen peroxide-releasing capacity of monocyte-derived macrophages from patients with lepromatous leprosy. (1986) (36)
- Comparison of pentoxifylline, thalidomide and prednisone in the treatment of ENL. (1998) (36)
- Detection and treatment of subclinical tuberculosis. (2012) (36)
- Cryptococcal glucuronoxylomannan delays translocation of leukocytes across the blood–brain barrier in an animal model of acute bacterial meningitis (2000) (35)
- Suppressive effect of leukemia virus-infected lymphoid cells on in vitro immunization of normal splenocytes. (1974) (35)
- Experimental Tuberculosis in the Wistar Rat: A Model for Protective Immunity and Control of Infection (2011) (35)
- The cutaneous infiltrates of leprosy. A transmission electron microscopy study (1983) (35)
- Thalidomide as an anti-TNF-alpha inhibitor: implications for clinical use. (1996) (34)
- Induction of Granulysin and Perforin Cytolytic Mediator Expression in 10-Week-Old Infants Vaccinated with BCG at Birth (2010) (34)
- Nonadherent cultures of human monocytes kill Mycobacterium smegmatis, but adherent cultures do not (1996) (33)
- Regulation of Acquired Immunity by γδ T‐Cell/Dendritic‐Cell Interactions (2005) (33)
- Exposure of Cord Blood to Mycobacterium bovis BCG Induces an Innate Response but Not a T-Cell Cytokine Response (2008) (32)
- Localization of receptors and early events of phagocytosis in the macrophage. (1975) (31)
- Thalidomide in toxic epidermal necrolysis (1999) (31)
- Significantly skewed memory CD8+ T cell subsets in HIV-1 infected infants during the first year of life. (2009) (30)
- A Subset of Circulating Blood Mycobacteria-Specific CD4 T Cells Can Predict the Time to Mycobacterium tuberculosis Sputum Culture Conversion (2014) (29)
- Leprosy and cell-mediated immunity. (1991) (29)
- A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis (2018) (29)
- Effect of thalidomide on the inflammatory response in cerebrospinal fluid in experimental bacterial meningitis. (1995) (28)
- The immunobiology of leprosy. (1986) (28)
- Specific T cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis, Following BCG Vaccination of Newborns (2010) (28)
- The Morphology of Echinoid Phagocytes and Mouse Peritoneal Macrophages During Phagocytosis in Vitro (1977) (27)
- Modulation of Hyperoxia-induced TNF-α Expression in the Newborn Rat Lung by Thalidomide and Dexamethasone (2000) (26)
- Properties of a murine monocytic tumor cell line J-774 in vitro. I. Morphology and endocytosis. (1978) (26)
- Coinfection of fibroblasts with Coxiella burnetti and Toxoplasma gondii: to each their own. (2000) (26)
- Strain-specific mycobacterial lipids and the stimulation of protective immunity to tuberculosis. (2005) (25)
- Efficacy of a cell-mediated reaction to the purified protein derivative of tuberculin in the disposal of Mycobacterium leprae from human skin. (1988) (24)
- Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis (2016) (24)
- Difference in the Effect of Immobilized Ligands on the Fc and C3 Receptors of Mouse Peritoneal Macrophages in Vitro (1978) (24)
- Regulation of acquired immunity by gamma delta T-cell/dendritic-cell interactions. (2005) (23)
- Etanercept exacerbates inflammation and pathology in a rabbit model of active pulmonary tuberculosis. (2014) (23)
- Epidemiologic consequences of microvariation in Mycobacterium tuberculosis. (2012) (22)
- Immunohistological characterization of spinal TB granulomas from HIV-negative and -positive patients. (2013) (22)
- Reversal of leukemia virus-induced immunosuppression in vitro by peritoneal macrophages. (1975) (22)
- T- and B-cell-independent activation of syngeneic macrophages by murine sarcoma cells. (1980) (22)
- Recombinant interleukin 2 adjunctive therapy in multidrug-resistant tuberculosis. (1998) (21)
- Mycobacterium leprae alters classical activation of human monocytes in vitro (2016) (21)
- Intradermal Recombinant Interleukin 2 Enhances Peripheral Blood T‐Cell Responses to Mitogen and Antigens in Patients with Lepromatous Leprosy (1990) (21)
- Differential Gene Expression in Response to Adjunctive Recombinant Human Interleukin-2 Immunotherapy in Multidrug-Resistant Tuberculosis Patients (1998) (21)
- Correlation of rpoB Mutations with Minimal Inhibitory Concentration of Rifampin and Rifabutin in Mycobacterium tuberculosis in an HIV/AIDS Endemic Setting, South Africa (2016) (21)
- Mycobacterium leprae-induced interferon-gamma production by household contacts of leprosy patients: association with the development of active disease. (1991) (21)
- In vivo administration of low-dose human interleukin-2 induces lymphokine-activated killer cells for enhanced cytolysis in vitro. (1991) (20)
- Regulation of cell-mediated immunity in lepromatous leprosy. (1986) (20)
- Modulation of the cytokine response in human monocytes by mycobacterium leprae phenolic glycolipid-1. (2012) (20)
- Endocytosis by Macrophages (1980) (20)
- Safety, tolerability, and pharmacokinetic effects of thalidomide in patients infected with human immunodeficiency virus: AIDS Clinical Trials Group 267. (2002) (19)
- Gemfibrozil Inhibits Legionella pneumophila and Mycobacterium tuberculosis Enoyl Coenzyme A Reductases and Blocks Intracellular Growth of These Bacteria in Macrophages (2009) (19)
- Cutaneous response to recombinant interleukin 2 in human immunodeficiency virus 1-seropositive individuals. (1990) (19)
- SHORT ANALYTICAL REVIEW Thalidomide as an Anti-TNF-a Inhibitor: Implications for Clinical Use (1996) (18)
- Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols. (2021) (18)
- Macrophages phagocytose thymic lymphocytes with productively rearranged T cell receptor alpha and beta genes (1988) (17)
- How Mycobacterium leprae infects peripheral nerves. (1999) (17)
- Detection of Mycobacterium tuberculosis in latently infected lungs by immunohistochemistry and confocal microscopy. (2014) (17)
- bis-Molybdopterin Guanine Dinucleotide Is Required for Persistence of Mycobacterium tuberculosis in Guinea Pigs (2014) (16)
- Aerosol Infection of Mice with Mycobacteria Using a Nose-Only Exposure Device (1997) (16)
- A combination of baseline plasma immune markers can predict therapeutic response in multidrug resistant tuberculosis (2017) (15)
- Effect of rhuIFN-gamma treatment in multibacillary leprosy patients. (1996) (15)
- Quantitative and Functional Differences between Peripheral Blood Myeloid Dendritic Cells from Patients with Pleural and Parenchymal Lung Tuberculosis (2006) (15)
- Potential of thalidomide and thalidomide analogues as immunomodulatory drugs in leprosy and leprosy reactions. (2000) (14)
- Dose-Dependent Immune Response to Mycobacterium bovis BCG Vaccination in Neonates (2006) (13)
- Dendritic Cells and Macrophages — Current Knowledge of Their Distinctive Properties and Functions (1980) (13)
- The immunomodulatory effects of thalidomide on human immunodeficiency virus-infected children. (2001) (13)
- Influence of Mycobacterium leprae and its soluble products on the cutaneous responsiveness of leprosy patients to antigen and recombinant interleukin 2. (1989) (13)
- BCG Induces Protection against Mycobacterium tuberculosis Infection in the Wistar Rat Model (2011) (13)
- Experimental Animal Models of Tuberculosis (2017) (12)
- Rational vaccine development--a new trend in tuberculosis control. (2005) (12)
- TNFα regulation of HIV1: biology and therapy (1994) (12)
- Properties of a murine monocytic tumor cell line J-774 in vitro. II. Enzyme activities. (1978) (12)
- Hansen's disease, cell-mediated immunity, and recombinant lymphokines. (1991) (11)
- Effect of treatment on the cellular composition of cutaneous lesions in leprosy patients. (1984) (11)
- Effect of cutaneous cell-mediated immune response to rIFN gamma on Mycobacterium leprae viability in the lesions of lepromatous leprosy. (1992) (11)
- Aggregation state of Mycobacterium tuberculosis impacts host immunity and augments pulmonary disease pathology (2021) (11)
- Plasma interferon-gamma-inducible protein 10 can be used to predict viral load in HIV-1-infected individuals. (2013) (11)
- Local nerve damage in leprosy does not lead to an impaired cellular immune response or decreased wound healing in the skin. (2002) (11)
- A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings (2016) (11)
- Cellular immunity in lepromatous and tuberculoid leprosy. (1985) (11)
- A multidrug-resistant, acr1-deficient clinical isolate of Mycobacterium tuberculosis is unimpaired for replication in macrophages. (2006) (10)
- Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model (2020) (10)
- Factors affecting tuberculosis strain success over 10 years in a high TB- and HIV-burdened community. (2014) (9)
- In Vitro Cytotoxicity of Mouse Macrophages Activated by Coculture with Syngeneic Sarcoma Cells (1982) (9)
- Aerosol Exposure System for Rabbits: Application to M. Tuberculosis Infection (2006) (9)
- Pulmonary Tuberculosis in the Rabbit (2016) (9)
- Inoculum size and traits of the infecting clinical strain define the protection level against Mycobacterium tuberculosis infection in a rabbit model (2019) (8)
- Frequency of Circulating CD4+Ki67+HLA-DR− T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to Culture Conversion (2018) (8)
- Tuberculosis control in crisis-causes and solutions. (2020) (8)
- Genetic Variation in TLR Genes in Ugandan and South African Populations and Comparison with HapMap Data (2012) (8)
- Heterogeneity in surface glycoproteins of mouse peritoneal macrophage populations. (1981) (7)
- Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response (2021) (7)
- Pulmonary Tuberculosis in the Rat (2010) (7)
- The emerging role of thalidomide therapy in HIV-infected patients (1997) (6)
- Effects of Intradermal Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Langerhans Cell Recruitment and Keratinocyte Growth (1993) (6)
- Molecular mechanism of nerve infection in leprosy. (1999) (6)
- HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load. (2011) (6)
- DENDRITIC CELLS, AN IMPORTANT NEW CELL TYPE IN MHC-LINKED FUNCTIONS (1980) (5)
- The efficacy of a cell-mediated reaction in the disposal of M. leprae in human skin. (1988) (5)
- Rabbit model of mycobacterial diseases. (2015) (5)
- Leprosy a model for cell mediated immunity: the effects and consequences of recombinant lymphokine immunotherapy (1992) (5)
- Thalidomide in Multiple Myeloma—From the Clinic to the Laboratory (2002) (5)
- The Role of Receptors in Endocytosis (1981) (4)
- Induction of Macrophage Microbicidal Activity (1980) (4)
- Use of IMiD3, a Thalidomide Analog, as an Adjunct to Therapy for Experimental Tuberculous Meningitis (2002) (4)
- Author Correction: The wide utility of rabbits as models of human diseases (2018) (4)
- Dendritic Cells in Host Immunity to Mycobacterium tuberculosis (2005) (4)
- Structural Modifications of Thalidomide Produce Analogues with Enhanced Tumor Necrosis Factor Inhibitory Activity. (1996) (4)
- Hansen's disease as a research model. (1984) (3)
- Thalidomide Exerts Its Inhibitory Action on Tumor Necrosis Factor oe by Enhancing m R N A Degradation (2003) (3)
- TNF alpha regulation of HIV1: biology and therapy. (1994) (3)
- Tuberculosis research comes of age (1998) (3)
- BCG Vaccination of Infants Confers Mycobacterium tuberculosis Strain-Specific Immune Responses by Leukocytes. (2020) (2)
- Tuberculosis: integrating host and pathogen biology. A summary of the 2005 Keystone Symposia. (2006) (2)
- Amino‐Substituted Thalidomide Analogues: Potent Inhibitors of TNF‐α Production. (1999) (2)
- Tumour-activated macrophages as effector cells in a tumour neutralization assay in vivo. (1983) (2)
- Human α-1-acid Glycoprotein Inhibits TNF Production in the CNS of Rabbits with Meningitis: A Report of Preliminary Observations (2004) (2)
- The role of rIL-2 in the modulation of cellular immunity in resistance to infection. (1991) (2)
- Cell mediated immunity in lepromatous and tuberculoid leprosy (1985) (2)
- Placenta Derived Stem Cells (PDAC) Suppress the Allo-MLR and the EBV Regression Assay. (2006) (2)
- Inhibitors of TNF-Thalidomide Analogues That Are Potent Activation by Two Distinct Classes of Differential Cytokine Modulation and T Cell (1999) (2)
- Thalidomide Selectively Inhibits Tumor Necrosis Factor ac Production by Stimulated (1991) (1)
- Macrophages in tuberculosis: friend or foe (2013) (1)
- Gemfibrozil Inhibits Legionella pneumophila and Mycobacterium tuberculosis (2009) (1)
- TB day summit in upstate New York: Key issues to address (2009) (1)
- HowMycobacterium lepraeinfects peripheral nerves (1999) (1)
- The role of rIL-2 in the modulation of cellular immunity in resistance to infection. (1991) (1)
- Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits (2013) (1)
- Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages (2012) (1)
- CTL differentiation and function (PP-108) (2010) (0)
- Complex Cytokine and Phenotypic Profiles Human Newborns Induces T Cells with Bacillus Calmette-Guérin Vaccination of (2008) (0)
- Cellular Immune Response toMycobacterium lepraeInfection in Human Immunodeficiency Virus-Infected Individuals (1995) (0)
- Dramatically Impaired BCG‐specific Immune Response in HIV+ Infants (2008) (0)
- Endocytic trafficking and the mycobacterial vacuole - General discussion I (1998) (0)
- Thalidomide Exerts Its Inhibitory Action on Tumor Necrosis Factor oe by Enhancing mRNA Degradation By Andre L. Moreira,* Elizabeth P. Sampaio,*S Antonina Zmuidzinas,* (1993) (0)
- A novel role for C–C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis (2018) (0)
- Tuberculosis research comes of age. Keystone Symposium on Tuberculosis: Molecular Mechanisms and Immunologic Aspects. (1998) (0)
- Cell-mediated immunity to mycobacteria: the effect of cytolysis on parasite viability (1992) (0)
- Association of Toll-like Receptor polymorphisms with variation in BCG-induced immunity (2009) (0)
- Cytokine and phenotypic profiles of specific T cells induced by newborn BCG vaccination (47.1) (2007) (0)
- Immunity to mycobacterial infection (PP-061) (2010) (0)
- Gaudernack, G. Preparation and characterization of a monoclonal antibody against human monocytes (2003) (0)
- The Rabbit Model for Assessing Host-Directed Therapies for Tuberculosis (2020) (0)
- THALIDOMIDE IN TOXIC EPIDERMAL NECROLYSIS. AUTHOR'S REPLY (1999) (0)
- The resuscitation-promoting factors of are required for virulence and resuscitation from dormancy bu (2011) (0)
- Placenta Derived Adherent Cells (PDACs) Suppress Tumor Cells of Diverse Origin. (2006) (0)
- Isolates Vivo and In Vitro , But Is Not More Virulent Induces a More Vigorous Host Response In CDC 1551 Mycobacterium tuberculosis (1999) (0)
- LoadHumans Is Associated with Mycobacterial -Specific T Cell Responses in tuberculosis Mycobacterium Functional Capacity of (2011) (0)
- TB - The Next Frontier (2014) (0)
- Association of Toll-like Receptor polymorphisms with variation in BCG-induced immunity (133.33) (2009) (0)
- Reply to Crawford (2006) (0)
- Mycobacterium leprae alters classical activation of human monocytes in vitro (2016) (0)
- The role of cytokines in protection and immunopathology in tuberculosis (1995) (0)
- VolunteersPathergy Reaction and Normal Healthy Wound-Healing Responses Occurring in the Characterization of the Divergent (2006) (0)
- The influence of M. Leprae and its soluble products on the cutaneous responsiveness of leprosy patients to antigen (1989) (0)
- Immunity to intracellular bacteria: editorial overview (1996) (0)
- The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th Annual Research Conference, New Orleans, Louisiana, USA, 15-17 July 2001. Abstracts. (2002) (0)
- The Role of Resuscitation Promoting Factors in the Virulence of Mycobacterium tuberculosis (2007) (0)
- Tuberculosis Research at the Millennium: A report from the Fourth International Conference on the Pathogenesis of Mycobacterial Infection, Stockholm, Sweden (2000) (0)
- Immune Suppression by Placenta Derived Adherent Cells (PDAC) Correlate with Monocyte Chemoattractant Protein-1 and IL-2 Secretion. (2006) (0)
- Erratum: Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis (Antimicrobial Agents and Chemotherapy (2002) 46:6 (1887-1895)) (2002) (0)
- Su.84. Cytokine Profile of Specific T-Cells Induced By Newborn Bcg Vaccination (2006) (0)
- BCG vaccination of infants confers Mycobacterium tuberculosis strain-specific immune responses to leucocytes (2020) (0)
- CD1d/NKT cells (WS-006) Chairpersons: Ken-ichiro Seino, Dale Godfrey (2010) (0)
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