Gioacchino Natoli
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Computer Science
Gioacchino Natoli's Degrees
- PhD Computer Science University of Milan
- Masters Computer Science University of Milan
- Bachelors Computer Science University of Milan
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(Suggest an Edit or Addition)Gioacchino Natoli's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Macrophage activation and polarization: nomenclature and experimental guidelines. (2014) (4128)
- Transcriptional regulation of macrophage polarization: enabling diversity with identity (2011) (1716)
- Trained immunity: A program of innate immune memory in health and disease (2016) (1587)
- Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase (2000) (1415)
- The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing (2007) (884)
- A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers (2010) (800)
- IKK-γ is an essential regulatory subunit of the IκB kinase complex (1998) (746)
- p38-dependent marking of inflammatory genes for increased NF-κB recruitment (2002) (688)
- Latent Enhancers Activated by Stimulation in Differentiated Cells (2013) (660)
- The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) (1998) (658)
- Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. (2010) (623)
- Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor κB (2009) (588)
- Transcriptional regulation via the NF-κB signaling module (2006) (553)
- Macrophages and cancer: from mechanisms to therapeutic implications. (2015) (532)
- Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway (1997) (472)
- Two Waves of Nuclear Factor κb Recruitment to Target Promoters (2001) (424)
- Transcript Dynamics of Proinflammatory Genes Revealed by Sequence Analysis of Subcellular RNA Fractions (2012) (421)
- Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes (2003) (392)
- Jmjd3 contributes to the control of gene expression in LPS-activated macrophages (2009) (389)
- IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. (1998) (382)
- Molecular control of activation and priming in macrophages (2015) (373)
- Noncoding transcription at enhancers: general principles and functional models. (2012) (368)
- Inhibition of NF-κB Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of IκB Kinase* (2000) (348)
- Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma (2013) (344)
- p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. (2002) (322)
- Transcriptional regulation via the NF-kappaB signaling module. (2006) (313)
- Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages (2012) (306)
- Modulation of NF-κB Activity by Exchange of Dimers (2003) (291)
- Degradation of Promoter-bound p65/RelA Is Essential for the Prompt Termination of the Nuclear Factor κB Response (2004) (280)
- Interactions of NF-κB with chromatin: the art of being at the right place at the right time (2005) (256)
- Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes. (2002) (223)
- Arginine methyltransferase CARM1 is a promoter‐specific regulator of NF‐κB‐dependent gene expression (2005) (215)
- The Histone H3 Lysine 27-Specific Demethylase Jmjd3 Is Required for Neural Commitment (2008) (208)
- The hepatitis B virus X gene induces p53-mediated programmed cell death. (1997) (207)
- A hyper‐dynamic equilibrium between promoter‐bound and nucleoplasmic dimers controls NF‐κB‐dependent gene activity (2006) (206)
- Maintaining cell identity through global control of genomic organization. (2010) (200)
- Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. (2014) (181)
- Hepatitis B virus pX activates NF-kappa B-dependent transcription through a Raf-independent pathway (1996) (157)
- Chromatin contributions to the regulation of innate immunity. (2014) (157)
- Resistance to Fas-mediated apoptosis in human hepatoma cells. (1995) (156)
- Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling. (1998) (155)
- Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs. (2010) (154)
- Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross talks (2017) (150)
- The genomic landscapes of inflammation. (2011) (146)
- Modulation of NF-kappaB activity by exchange of dimers. (2003) (145)
- Ras- and Raf-dependent activation of c-jun transcriptional activity by the hepatitis B virus transactivator pX. (1994) (139)
- Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX (1994) (138)
- Inhibition of NF-kappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase. (2000) (138)
- Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation (2018) (137)
- Reactive Oxygen Intermediates Mediate Angiotensin II-induced c-Jun•c-Fos Heterodimer DNA Binding Activity and Proliferative Hypertrophic Responses in Myogenic Cells (*) (1995) (135)
- Tumor Necrosis Factor (TNF) Receptor 1 Signaling Downstream of TNF Receptor-associated Factor 2 (1997) (119)
- A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. (2005) (116)
- Genome-Organizing Factors Top2 and Hmo1 Prevent Chromosome Fragility at Sites of S phase Transcription (2009) (116)
- Nuclear Ubiquitin Ligases, NF-κB Degradation, and the Control of Inflammation (2008) (114)
- Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level. (1991) (112)
- Nuclear Factor kB-independent Cytoprotective Pathways Originating at Tumor Necrosis Factor Receptor-associated Factor 2* (1998) (109)
- Dissection of transcriptional and cis‐regulatory control of differentiation in human pancreatic cancer (2016) (103)
- Control of NF-kappaB-dependent transcriptional responses by chromatin organization. (2009) (99)
- A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages (2015) (99)
- The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. (2012) (95)
- Transcriptional control of inflammatory responses. (2014) (91)
- Adaptation and memory in immune responses (2019) (84)
- Big data in IBD: a look into the future (2019) (83)
- Short-term memory of danger signals and environmental stimuli in immune cells (2013) (82)
- Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils (2015) (79)
- Two Modes of Transcriptional Activation at Native Promoters by NF-κB p65 (2009) (76)
- Defective and nondefective adenovirus vectors for expressing foreign genes in vitro and in vivo. (1991) (74)
- ADP-ribosyltransferases, an update on function and nomenclature (2021) (74)
- The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesis. (2012) (71)
- Trans-activation of epidermal growth factor receptor gene by the hepatitis B virus X-gene product. (1993) (70)
- TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities. (2016) (69)
- Hepatitis B virus X protein transactivates the long terminal repeats of human immunodeficiency virus types 1 and 2 (1990) (67)
- The hepatitis B virus (HBV) pX transactivates the c-fos promoter through multiple cis-acting elements. (1993) (66)
- Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis. (1997) (65)
- Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination. (2015) (63)
- Cutting Edge: An Inactive Chromatin Configuration at the IL-10 Locus in Human Neutrophils (2013) (63)
- Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers (2020) (63)
- Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs (2020) (59)
- Tuning up inflammation: How DNA sequence and chromatin organization control the induction of inflammatory genes by NF‐κB (2006) (58)
- NF‐κB and chromatin: ten years on the path from basic mechanisms to candidate drugs (2012) (57)
- In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype. (2016) (57)
- Antibodies to hepatitis C virus in patients with hepatocellular carcinoma. (1991) (57)
- Intracellular localization of full-length and truncated hepatitis C virus core protein expressed in mammalian cells. (1994) (57)
- Correction tp Macrophage activation and polarization: Nomenclature and experimental guidelines [Immunity, 41, 2014 (14-20)] (2014) (51)
- PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN–Inducible Proteins (2018) (49)
- Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency (2014) (49)
- CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors (2015) (49)
- Transcriptional determination and functional specificity of myeloid cells: making sense of diversity (2017) (49)
- Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis (2021) (47)
- Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies up to 25 April 2020 and public health implications (2020) (46)
- Hepatitis B virus X gene product acts as a transactivator in vivo. (1994) (45)
- MyoD prevents cyclinA/cdk2 containing E2F complexes formation in terminally differentiated myocytes (1997) (44)
- Characterization of the hepatitis B virus preS/S region encoded transcriptional transactivator. (1992) (35)
- When Sirtuins and NF-κB Collide (2009) (35)
- High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins. (2017) (35)
- A molecular network regulating the pro-inflammatory phenotype of human memory T lymphocytes (2020) (34)
- Shaping alternative NF-κB-dependent gene expression programs: new clues to specificity (2006) (33)
- Lineages, cell types and functional states: a genomic view. (2013) (32)
- Epigenetic regulation of neutrophil development and function. (2016) (31)
- Transcriptional control of macrophage diversity and specialization (2011) (30)
- Macrophage activation: glancing into diversity. (2014) (28)
- Reactive Oxygen Intermediates (ROIs) Are Involved in the Intracellular Transduction of Angiotensin II Signal in C2C12 Cells (1995) (27)
- Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity (2018) (25)
- Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2. Nuclear factor kappaB (NFkappaB)-inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c-Jun N-terminal kinase/stress-activated protein kinase. (1997) (24)
- The future therapeutic potential of histone demethylases: A critical analysis. (2009) (23)
- Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells (2019) (22)
- Rapamycin‐sensitive signals control TCR/CD28‐driven Ifng, Il4 and Foxp3 transcription and promoter region methylation (2011) (21)
- Little Things that Count in Transcriptional Regulation (2004) (21)
- Modulation of intracellular signal transduction pathways by the hepatitis B virus transactivator pX. (1995) (20)
- The gene (LGALS3BP) encoding the serum protein 90K, associated with cancer and infection by the human immunodeficiency virus, maps at 17q25. (1995) (20)
- Deciphering cis-regulatory control in inflammatory cells (2013) (19)
- FOXA2 controls the cis‐regulatory networks of pancreatic cancer cells in a differentiation grade‐specific manner (2019) (19)
- WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells (2019) (18)
- The hepatitis B virus X protein transactivation of c-fos and c-myc proto-oncogenes is mediated by multiple transcription factors. (1992) (17)
- Mutual epithelium‐macrophage dependency in liver carcinogenesis mediated by ST18 (2016) (16)
- Acute necrotizing encephalopathy: a relapsing case in a European adult (2007) (15)
- A first exon termination checkpoint preferentially suppresses extragenic transcription (2021) (15)
- Women and Other Mafia-Type Criminal Organizations (2007) (14)
- Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis. (2020) (14)
- Arginine methyltransferase CARM 1 is a promoter-specific regulator of NF-j B-dependent gene expression (2013) (14)
- Fish the ChIPs: a pipeline for automated genomic annotation of ChIP-Seq data (2011) (13)
- Detection of replicative intermediates of viral RNA in peripheral blood mononuclear cells from chronic hepatitis C virus carriers. (1993) (13)
- Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cells. (2006) (13)
- A birthday gift for TRADD (2008) (13)
- Specialized chromatin patterns in the control of inflammatory gene expression. (2011) (13)
- Transcriptional Control of Inflammatory (2014) (12)
- Functional genomics of the inflammatory response: where are we now? (2013) (12)
- Understanding Spontaneous Conversion: The Case of the Ly6C- Monocyte. (2017) (12)
- Specificity and Function of IRF Family Transcription Factors: Insights from Genomics. (2016) (11)
- The hepatitis B virus X gene product transactivates the HIV-LTR in vivo. (1993) (11)
- Supplementary Information S1 (2008) (11)
- Two Functionally Distinct Subsets of Mast Cells Discriminated By IL-2–Independent CD25 Activities (2014) (11)
- Tumor cell heterogeneity and its transcriptional bases in pancreatic cancer: a tale of two cell types and their many variants (2021) (10)
- NF‐κB: no longer an island, but a piece of a continent (2010) (8)
- A shortcut for early macrophage recruitment into tumors by activated oncogenes. (2017) (8)
- The molecular basis of myocardial hypertrophy. (1994) (7)
- An inactive chromatin configuration at the IL-10 locus in human neutrophils (2013) (7)
- Integration of transcriptional and metabolic control in macrophage activation (2021) (6)
- Meta-analysis of diagnostic performance of serological tests for SARS-CoV-2 antibodies and public health implications (2020) (6)
- Lower probability and shorter duration of infections after COVID-19 vaccine correlate with anti-SARS-CoV-2 circulating IgGs (2021) (6)
- Non-coding transcription at cis-regulatory elements: computational and experimental approaches. (2013) (6)
- Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage (2018) (5)
- H3K9 trimethylation in active chromatin restricts the usage of functional CTCF sites in SINE B2 repeats (2022) (5)
- Erratum: TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities (Cell Reports (2016) 15 (7)(1566#x2013;1579) (S2211124716304715) (10.1016/j.celrep.2016.04.044)) (2017) (5)
- Inhibition of NFk B Activation by Arsenite through Reaction with a Critical Cysteine in the Activation Loop of I k B Kinase * (2000) (5)
- Current challenges in understanding the role of enhancers in disease. (2022) (5)
- Expression of the c‐myc protooncogene product in cells infected with the hepatitis delta virus (1994) (4)
- Hepatitis B virus and hepatocellular carcinoma: a possible role for the viral transactivators. (1991) (4)
- Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8. (2021) (4)
- A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes (2020) (4)
- TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities. (2017) (3)
- Housekeeping and tissue-specific cis-regulatory elements: Recipes for specificity and recipes for activity (2018) (3)
- RFX transcription factors control a miR-150/PDAP1 axis that restrains the proliferation of human T cells (2022) (3)
- Interferon regulatory factor 1 (IRF1) controls the metabolic programmes of low-grade pancreatic cancer cells (2022) (2)
- Non-Cooperative Interactions Between Transcription Factors and Clustered DNA Binding Sites Enable Graded Transcriptional Responses To Environmental Inputs (2010) (2)
- DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon (2022) (2)
- Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease (2022) (2)
- Truncated pre-S/S proteins transactivate multiple target sequences. (1992) (2)
- Correction: Corrigendum: Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency (2015) (2)
- Hepatitis C viral RNA in serum of Italian patients with chronic NANBH (1991) (1)
- Erratum: The human toll signaling pathway: Divergence of nuclear factor κb and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6) (Journal of Immunology (1998) 187 (2097-2101)) (2013) (1)
- Characterization of the hepatitis B virus transactivators: A possible direct role of the virus in the development of hepatocellular carcinoma (1993) (1)
- Transcription factors as drivers of distinct pancreatic ductal adenocarcinoma (PDAC) programmes: a role for HNF4A (2020) (1)
- Supplemental Information TET 2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities (2016) (1)
- Transcriptional repressors as guardians of tissue macrophage identity (2019) (1)
- When antimicrobial peptides hit the wrong target: a novel link between tumour macrophages and cancer stem cells (2015) (1)
- Induction oftheDNA-Binding Activity ofc-Jun/c-Fos Heterodimers bytheHepatitis B VirusTransactivator pX (1994) (1)
- From the Beauty of Genomic Landscapes to the Strength of Transcriptional Mechanisms (2016) (1)
- Independent - Cells Discriminated By IL-2 Two Functionally Distinct Subsets of Mast (2014) (0)
- A Graded Response of a Transcription Factor to Increasing Doses of External Stimuli: A Thermodynamic Framework Describing the Behavior of NF-kB (2009) (0)
- Subject Index, Vol. 69, 1995 (2004) (0)
- Adaptation and memory in immune responses (2019) (0)
- Chromatin configurations correlate with the differential capacity of human neutrophils and monocytes to express IL-6 and IL-10 in response to LPS (2013) (0)
- Shiftworking keeps locked-down lab on track (2020) (0)
- Women and other Mafia-type organization (2007) (0)
- Chromatin Mediated Control of Gene Expression in Innate Immunity and Inflammation (2010) (0)
- Characterization of the transactivating properties of the hepatitis B virus (HBV) X protein (1989) (0)
- Detection of Copy Number Variations from Targeted Re-sequencing data (2013) (0)
- Clonal hematopoiesis, inflammation, and cardiovascular disorders: a mitochondrial connection. (2022) (0)
- The Control of Gene Expression in Macrophages (2014) (0)
- The activation of the immediate early proliferation dependent genes by pHBx involves the modification of cellular transcription factors (1991) (0)
- Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation (2018) (0)
- FASAPO1 MUTATIONS AND DEFECTIVE FAS-MEDIATED APOPTOSIS IN A CHILD WITH TYPE 2a AUTOIMMUNE HEPATITIS. (1997) (0)
- The AP1 Transcription Factor as a Model to Study the Modulation of Intracellular Signalling Pathways by the Hepatitis B Virus Transactivator pX (1994) (0)
- Cell-specific epigenetic landscapes drive differential IL-6 gene expression in human neutrophils and monocytes (2014) (0)
- The histone demethylase Jarid1b as a component of transcriptional regulatory circuits involved in the inflammatory response (2008) (0)
- HCV genotype and serum 90L levels: Host and virus related factors predict response to a-IFN therapy (1995) (0)
- Characterization of the sequences acitivated by the truncated pre-S/S proteins (1991) (0)
- Coexisting morpho-biotypes unveil the regulatory bases of phenotypic plasticity in pancreatic ductal adenocarcinoma (2022) (0)
- Raf-independent pathway . B-dependent transcription through a Hepatitis B virus pX activates NF-kappa (1995) (0)
- Functional dissection of the histone H3 lysine 27-demethylase Jmjd3 in the maturation of the respiratory network (2012) (0)
- The Macrophage Epigenome and the Control of Inflammatory Gene Expression (2014) (0)
- In vivo expression of the hepatitis B virus X protein in transgenic mice (1989) (0)
- The activation of a latent HIV genome by HBV involves the ubiquitous transcription factor kB (1991) (0)
- Neutrophilsat the IL-10 Locus in Human Cutting Edge: An Inactive Chromatin (2013) (0)
- Achieving Transcriptional Specificity in NF-κB-Dependent Inflammatory Gene Expression (2006) (0)
- Transactivation of the human immunodeficiency viruses (HIV1 and HIV2) long terminal repeats (LTRs) by the HBV X gene product (1989) (0)
- WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells (2019) (0)
- PO-324 Interferon regulatory factor 1 (IRF1) regulates inflammatory and metabolic phenotypes in pancreatic ductal adenocarcinoma (2018) (0)
- Accumulation of a cellular protein bearing c-myc-like antigenicity in hepatic and non-hepatic delta antigen expressing cells. (1993) (0)
- Absence of HTLV-Related Sequences in Skin Lesions and Peripheral Blood of Cutaneous T-Cell Lymphomas (2009) (0)
- Women and the Mafia STUDIES IN ORGANIZED CRIME (2013) (0)
- Abstract LB-202: Role of the FOXA transcription factors in shaping distinct transcriptional programs in human pancreatic cancers (2018) (0)
- c-myc expression in cells infected with hepatitis delta virus. (1993) (0)
- PO-178 WDR5 promotes metastasis dissemination in breast cancer (2018) (0)
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