Giorgio Carta
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Italian bioengineer
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Bioengineering
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Biomedical Engineering
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Engineering
Why Is Giorgio Carta Influential?
(Suggest an Edit or Addition)According to Wikipedia, Giorgio Carta is an Italian chemical engineer. Carta completed a bachelor's of science degree in chemical engineering at the University of Cagliari in 1980, then pursued doctoral study in the subject at the University of Delaware. Upon obtaining his PhD in 1984, Carta joined the University of Virginia faculty, where he was later named Lawrence R. Quarles Professor of Chemical Engineering. He became a member of the organizing committee for the PREP International Symposium, Exhibition and Workshops on Preparative and Process Chromatography, Ion Exchange, Adsorption Processes and Related Separation Techniques in 1997, and has chaired or co-chaired the body since 2009. Carta was elected to fellowship of the American Institute for Medical and Biological Engineering in 2002, and was similarly honored by the American Institute of Chemical Engineers in 2007.
Giorgio Carta 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Protein Chromatography: Process Development and Scale-Up (2010) (242)
- Protein Adsorption on Cation Exchangers: Comparison of Macroporous and Gel‐Composite Media (1996) (181)
- Esterification of fatty acids using nylon-immobilized lipase in n-hexane: kinetic parameters and chain-length effects. (2002) (145)
- Protein Mass Transfer Kinetics in Ion Exchange Media: Measurements and Interpretations (2005) (132)
- Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography. (2007) (126)
- Enzymatic synthesis of esters using an immobilized lipase (1991) (100)
- Characterization of protein adsorption by composite silica-polyacrylamide gel anion exchangers I. Equilibrium and mass transfer in agitated contactors (1996) (98)
- Uptake of phenylalanine and tyrosine by a strong-acid cation exchanger (1989) (89)
- Toolboxes for a standardised and systematic study of glycans (2014) (82)
- Protein adsorption and transport in agarose and dextran-grafted agarose media for ion exchange chromatography: Effect of ionic strength and protein characteristics. (2009) (82)
- Fatty acid esterification using nylon‐immobilized lipase (1995) (75)
- Peak resolution in linear chromatography: Effects of intraparticle convection (1993) (73)
- Protein adsorption on novel acrylamido-based polymeric ion exchangers. II. Adsorption rates and column behavior. (2000) (72)
- Diffusion and convection in chromatographic processes using permeable supports with a bidisperse pore structure (1993) (70)
- Temperature Dependence of the Dissociation Constants of Several Amino Acids (2008) (70)
- IgG adsorption on a new protein A adsorbent based on macroporous hydrophilic polymers. I. Adsorption equilibrium and kinetics. (2009) (67)
- Rapid monoclonal antibody adsorption on dextran-grafted agarose media for ion-exchange chromatography. (2008) (64)
- Characterization of protein adsorption by composite silica-polyacrylamide gel anion exchangers II. Mass transfer in packed columns and predictability of breakthrough behavior (1996) (63)
- Protein adsorption on novel acrylamido-based polymeric ion-exchangers. IV. Effects of protein size on adsorption capacity and rate. (2002) (63)
- Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: I. Adsorption equilibrium. (2011) (62)
- pH transitions in cation exchange chromatographic columns containing weak acid groups. (2007) (61)
- Exact analytic solution of a mathematical model for chromatographic operations (1988) (60)
- Two-component protein adsorption kinetics in porous ion exchange media. (2005) (57)
- Binary protein adsorption on gel‐composite ion‐exchange media (1999) (56)
- Adsorption of amino acids on porous polymeric adsorbents—I. Equilibrium (1996) (55)
- Considerations in Compound Database Preparation-"Hidden" Impact on Virtual Screening Results (2005) (54)
- Separation of sugars by continuous annular chromatography (1988) (54)
- Properties and performance of novel high-resolution/high-permeability ion-exchange media for protein chromatography. (2005) (53)
- Effects of bovine serum albumin heterogeneity on frontal analysis with anion-exchange media. (2001) (52)
- Chromatography with permeable supports: Theory and comparison with experiments (1992) (51)
- Protein adsorption on novel acrylamido-based polymeric ion-exchangers. I. Morphology and equilibrium adsorption. (2000) (50)
- Synthesis of esters using a nylon-immobilized lipase in batch and continuous reactors. (1992) (50)
- Protein separations with induced pH gradients using cation-exchange chromatographic columns containing weak acid groups. (2008) (49)
- Adsorption kinetics of deamidated antibody variants on macroporous and dextran-grafted cation exchangers. III. Microscopic studies. (2011) (47)
- Ion exchange of amino acids and dipeptides on cation resins with varying degree of crosslinking. 1. Equilibrium (1993) (45)
- Protein adsorption and transport in cation exchangers with a rigid backbone matrix with and without polymeric surface extenders (2011) (45)
- Protein adsorption on novel acrylamido-based polymeric ion-exchangers. III. Salt concentration effects and elution behavior. (2001) (44)
- Equilibrium sorption of amino acids by a cation-exchange resin (1990) (44)
- Protein diffusion in charged polyacrylamide gels. Visualization and analysis. (1999) (44)
- Asymmetric Reduction of Acetophenone with Calcium‐Alginate‐Entrapped Baker's Yeast in Organic Solvents (1998) (44)
- Predicting protein dynamic binding capacity from batch adsorption tests. (2012) (43)
- Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part I. Chromatographic elution and batch adsorption behavior. (2014) (43)
- Asymmetric Ketone Reduction with Immobilized Yeast in Hexane: Biocatalyst Deactivation and Regeneration (2001) (43)
- Continuous separation of proteins by annular chromatography (1991) (43)
- Protein Transport in Constrained Anionic Hydrogels: Diffusion and Boundary-Layer Mass Transfer (2001) (42)
- Particle‐size distribution effects in batch adsorption (2003) (41)
- Unfolding and aggregation of monoclonal antibodies on cation exchange columns: effects of resin type, load buffer, and protein stability. (2015) (41)
- Displacement separations by continuous annular chromatography (1990) (40)
- Patterns of protein adsorption in chromatographic particles visualized by optical microscopy. (2007) (40)
- Unbiasing Scoring Functions: A New Normalization and Rescoring Strategy (2007) (39)
- The linear driving force approximation for cyclic mass transfer in spherical particles (1993) (38)
- Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry. (2014) (36)
- Absorption of nitric oxide in nitric acid and water (1983) (36)
- Protein adsorption and desorption on gel-filled rigid particles for ion exchange (1998) (36)
- Theory and applications of refractive index-based optical microscopy to measure protein mass transfer in spherical adsorbent particles. (2008) (35)
- Film model approximation for non-linear adsorption and diffusion in spherical particles (1998) (35)
- Radiotracer measurements of protein mass transfer: Kinetics in ion exchange media (2006) (35)
- Ion exchange of amino acids and dipeptides on cation resins with varying degree of crosslinking. 2. Intraparticle transport (1993) (35)
- Mesh Size of Charged Polyacrylamide Hydrogels from Partitioning Measurements (2005) (34)
- Continuous Regioselective Enzymatic Esterification in a Simulated Moving Bed Reactor (2002) (34)
- Adsorptive control of water in esterification with immobilized enzymes: I. Batch reactor behavior. (1998) (33)
- Separation of protein charge variants with induced pH gradients using anion exchange chromatographic columns (2008) (33)
- Protein adsorption equilibrium and kinetics in multimodal cation exchange resins (2016) (32)
- Multicomponent protein adsorption in supported cationic polyacrylamide hydrogels (2005) (31)
- Synthesis of lovastatin with immobilized Candida rugosa lipase in organic solvents: Effects of reaction conditions on initial rates. (1997) (31)
- Protein and virus-like particle adsorption on perfusion chromatography media. (2013) (31)
- Structural and functional characteristics of virgin and fouled Protein A MabSelect resin cycled in a monoclonal antibody purification process (2016) (29)
- Sugar Separations on a Pilot Scale by Continuous Annular Chromatography (1990) (28)
- Adsorption equilibrium and kinetics of monomer-dimer monoclonal antibody mixtures on a cation exchange resin. (2015) (28)
- IgG adsorption on a new protein A adsorbent based on macroporous hydrophilic polymers II. Pressure-flow curves and optimization for capture. (2009) (28)
- Modeling multicomponent adsorption of monoclonal antibody charge variants in cation exchange columns (2012) (27)
- Systematic interpolation method predicts protein chromatographic elution from batch isotherm data without a detailed mechanistic isotherm model. (2015) (27)
- Asymmetric Synthesis with Immobilized Yeast in Organic Solvents: Equilibrium Conversion and Effect of Reactant Partitioning on Whole Cell Biocatalysis (2003) (27)
- Nature of foulants and fouling mechanism in the Protein A MabSelect resin cycled in a monoclonal antibody purification process (2016) (27)
- Adsorption of amino acids on porous polymeric adsorbents—II. Intraparticle mass transfer (1996) (27)
- Adsorptive control of water in esterification with immobilized enzymes. Continuous operation in a periodic counter-current reactor. (1999) (25)
- Analytic solution for chromatography with nonuniform sorbent particles (1990) (25)
- Adsorption of polyethylene-glycolated bovine serum albumin on macroporous and polymer-grafted anion exchangers. (2014) (25)
- Multicomponent adsorption of monoclonal antibodies on macroporous and polymer grafted cation exchangers. (2012) (25)
- Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds. (2012) (25)
- Protein partitioning and transport in supported cationic acrylamide-based hydrogels (2003) (25)
- Adsorption of deamidated antibody variants on macroporous and dextran-grafted cation exchangers: II. Adsorption kinetics. (2011) (24)
- Linear driving force approximation for intraparticle diffusion and convection in permeable supports (1995) (23)
- Separation of antibody monomer-dimer mixtures by frontal analysis. (2017) (23)
- pH Transients in hydroxyapatite chromatography columns-experimental evidence and phenomenological modeling. (2010) (23)
- Separation of protein mixtures by continuous annular chromatography with step elution (1994) (23)
- Protein Chromatography (2020) (23)
- Particle size effects on protein and virus-like particle adsorption on perfusion chromatography media. (2015) (22)
- Productivity Considerations and Design Charts for Biomolecule Capture with Periodic Countercurrent Adsorption Systems (2010) (22)
- Lysine Adsorption on Cation Exchange Resin. I. Ion Exchange Equilibrium and Kinetics (2004) (21)
- Multiscale modeling of protein adsorption and transport in macroporous and polymer‐grafted ion exchangers (2014) (20)
- Counterion effects on protein adsorption equilibrium and kinetics in polymer-grafted cation exchangers. (2012) (20)
- Mass transfer in the absorption of nitrogen oxides in alkaline solutions (1988) (20)
- Role of nitrous acid in the absorption of nitrogen oxides in alkaline solutions (1984) (20)
- Effect of Aeration during Cell Growth on Ketone Reactions by Immobilized Yeast (2000) (20)
- Separation of Metals by Continuous Annular Chromatography with Step Elution (1989) (19)
- Surface induced three-peak elution behavior of a monoclonal antibody during cation exchange chromatography. (2016) (19)
- Adsorptive control of water in esterification with immobilized enzymes: II. fixed-bed reactor behavior. (1998) (19)
- Virtual screening for the identification of novel nonsteroidal glucocorticoid modulators. (2010) (19)
- Toward in silico CMC: An industrial collaborative approach to model‐based process development (2020) (17)
- Structure and protein adsorption mechanisms of clean and fouled tentacle-type anion exchangers used in a monoclonal antibody polishing step. (2013) (17)
- Identification of plasmepsin inhibitors as selective anti-malarial agents using ligand based drug design. (2011) (17)
- Protein adsorption in charged agarose gels studied by light microscopy (2007) (16)
- Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. I. Experimental observations and phenomenological model. (2019) (16)
- Diffusion, convection, and reaction in catalyst particles : analogy between slab and sphere geometries (1993) (16)
- Systematic interpolation method predicts protein chromatographic elution with salt gradients, pH gradients and combined salt/pH gradients. (2017) (16)
- Analytic solution for volume-overloaded gradient elution chromatography (1992) (16)
- Protein adsorption kinetics in charged agarose gels: Effect of agarose content and modeling (2009) (15)
- Protein adsorption in anion exchange resins – effects of polymer grafting, support structure porosity, and protein size (2018) (15)
- Exact solution and linear driving force approximation for cyclic mass transfer in a bidisperse sorbent (1993) (15)
- Evaluation of polymer matrices for an adsorptive approach to plasma detoxification. (2010) (15)
- pH transients in hydroxyapatite chromatography columns-Effects of operating conditions and media properties. (2010) (15)
- Downstream Processing of Biotechnology Products (2010) (14)
- Film Model Approximation for Multicomponent Adsorption (2000) (14)
- Effects of polymer graft properties on protein adsorption and transport in ion exchange chromatography: a multiscale modeling study. (2015) (14)
- Film Model Approximation for Particle-Diffusion-Controlled Multicomponent Ion Exchange (1999) (14)
- Chromatography of reversibly reacting mixtures: mutarotation effects in sugar separations (1992) (13)
- Comparison of perfusion media and monoliths for protein and virus-like particle chromatography. (2016) (13)
- Simultaneous Reaction and Chromatography (1991) (13)
- Effects of molecule size and resin structure on protein adsorption on multimodal anion exchange chromatography media. (2020) (13)
- Periodic countercurrent operation of sorption processes applied to water desalination with thermally regenerable ion-exchange resins (1986) (13)
- Temperature effects on equilibrium and mass transfer of phenylalanine in cation exchangers (1997) (13)
- Polyclonal and monoclonal IgG binding on protein A resins—Evidence of competitive binding effects (2017) (13)
- Enzymatic Transformations of Thio Acids and Thio Esters (1997) (12)
- Film Model Approximation for Particle-Diffusion-Controlled Binary Ion Exchange (1999) (12)
- Systematic Interpolation Method Predicts Antibody Monomer-Dimer Separation by Gradient Elution Chromatography at High Protein Loads. (2018) (12)
- Displacement chromatography of amino acids: Effects of selectivity reversal (1994) (12)
- Sorption of water from alcohol-water mixtures by cation-exchange resins (1987) (12)
- Structural and performance characteristics of representative anion exchange resins used for weak partitioning chromatography (2017) (11)
- Lysine Adsorption on Cation Exchange Resin. II. Column Adsorption/Desorption Behavior and Modeling (2004) (11)
- Chromatographic behavior of bivalent bispecific antibodies on cation exchange columns. II. Biomolecular perspectives. (2019) (11)
- Operating characteristics of a preparative-scale radial compression chromatograph in isocratic and gradient elution (1994) (10)
- On the Effects of Permuted Input on Conformational Sampling of Drug‐like Molecules: an Evaluation of Stochastic Proximity Embedding (2007) (10)
- Hindered diffusion of proteins in mixture adsorption on porous anion exchangers and impact on flow-through purification of large proteins. (2019) (10)
- Effects of protein properties on adsorption and transport in polymer‐grafted ion exchangers: A multiscale modeling study (2017) (10)
- Chapter 3. Chromatography Media (2010) (10)
- Gradient elution behavior of proteins in hydrophobic interaction chromatography with U-shaped retention factor curves. (2018) (10)
- Effect of irrigation on sap flux density variability and water use estimate in cherry (Prunus avium) for timber production: Azimuthal profile, radial profile and sapwood estimation (2016) (9)
- Frequency response of liquid-phase adsorption on polymeric adsorbents (1997) (9)
- Effects of negative and positive cooperative adsorption of proteins on hydrophobic interaction chromatography media. (2020) (9)
- Apolipoprotein A‐IMilano anion exchange chromatography: Self association and adsorption equilibrium (2010) (9)
- Assay for Recombinant and Native Human Intraacrosomal Antigen SP‐10 (1993) (9)
- Protein adsoprotein adsorption on core-shell particles: Comparison of Capto™ Core 400 and 700 resins. (2021) (8)
- Permuting input for more effective sampling of 3D conformer space (2006) (8)
- Structure and functional properties of Capto™ Core 700 core-shell particles. (2020) (8)
- Diffusion and convection in permeable particles: Analogy between slab and sphere geometries (1992) (8)
- Introduction to Protein Chromatography (2010) (8)
- Chapter 6. Adsorption Kinetics (2010) (7)
- Pilot-scale studies of sugar separations by continuous chromatography (1989) (7)
- Mixed-Beds of Strong and Weak Anion Exchange Resins for Protein Separations with Step-Induced pH Gradients (2014) (7)
- Lysine Adsorption on Cation Exchange Resin. III. Multicolumn Adsorption/Desorption Operation (2005) (7)
- Unbiasing Scoring Functions: A New Normalization and Rescoring Strategy. (2007) (7)
- Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-α. (2009) (7)
- Adsorption Calculations Using the Film Model Approximation for Intraparticle Mass Transfer (2003) (6)
- Competitive binding of monoclonal antibody monomer-dimer mixtures on ceramic hydroxyapatite. (2019) (6)
- Regioselective Enzymatic Diol Esterification in Batch and Fixed‐Bed Adsorptive Reactors: Experiments and Modeling (2000) (6)
- Analysis of gradient elution chromatography using the transport model (2020) (6)
- Chapter 8. Effects of Dispersion and Adsorption Kinetics on Column Performance (2010) (6)
- Study of radial compression high-performance liquid chromatographic columns for preparative chromatography (1995) (6)
- Chromatographic behavior of bivalent bispecific antibodies on hydrophobic interaction chromatography columns. (2020) (6)
- SCRUBBING OF NITROGEN OXIDES WITH NITRIC ACID SOLUTIONS (1986) (6)
- Predicting Retention and Resolution of Protein Charge Variants in Mixed-Beds of Strong and Weak Anion Exchange Resins with Step-Induced pH Gradients (2014) (5)
- Gradient elution behavior of proteins in hydrophobic interaction chromatography with a U-shaped retention factor curve under overloaded conditions. (2018) (5)
- Resolution of Protein Charge Variants in Mixed-Bed Chromatography Columns with Step-Induced pH Gradients at High Protein Loadings (2015) (5)
- Chemical modification of protein A chromatography ligands with polyethylene glycol. I: Effects on IgG adsorption equilibrium, kinetics, and transport. (2018) (5)
- Design of Chromatographic Processes (2010) (5)
- Chromatographic and adsorptive behavior of a bivalent bispecific antibody and associated fragments. (2021) (5)
- Gradient Elution Chromatography (2010) (4)
- ‘tieredScreen’ – Layered Virtual Screening Tool for the Identification of Novel Estrogen Receptor Alpha Modulators (2010) (4)
- Novel Applications of Continuous Annular Chromatography (1989) (4)
- Consensus Computational Ligand‐Based Design for the Identification of Novel Modulators of Human Estrogen Receptor Alpha (2012) (4)
- Role of configurational flexibility on the adsorption kinetics of bivalent bispecific antibodies on porous cation exchange resins. (2021) (4)
- Relationship between HETP measurements and breakthrough curves in short chromatography columns (2020) (4)
- Chemical modification of protein a chromatography ligands with polyethylene glycol. II: Effects on resin robustness and process selectivity. (2018) (4)
- Apolipoprotein A‐IMilano anion exchange chromatography: Mass transfer and adsorption kinetics (2010) (4)
- Rational structure-based drug design and optimization in the ligand-binding domain of the glucocorticoid receptor-α. (2009) (4)
- Analytical solution for cycling zone adsorption (1986) (4)
- Protein adsorption and separation with monomodal and multimodal anion exchange chromatography resins. Part I. Multicomponent adsorption properties and frontal chromatography (2022) (3)
- Patterns of protein adsorption in ion-exchange particles and columns: Evolution of protein concentration profiles during load, hold, and wash steps predicted for pore and solid diffusion mechanisms. (2021) (3)
- Simulated Moving Bed Chromatographic Reactors (1996) (3)
- Advanced techniques for energy-efficient industrial-scale continuous chromatography (1989) (2)
- Dynamics of competitive binding and separation of monoclonal antibody monomer-dimer mixtures in ceramic hydroxyapatite columns. (2020) (2)
- Effects of interfacial diffusive transport on the dynamics of oscillating reactions (1990) (2)
- Protein adsorption and separation with monomodal and multimodal anion exchange chromatography resins. Part II . Mechanisms of protein aggregation on the chromatographic surface (2022) (1)
- Separation of monoclonal antibody monomer-dimer mixtures by gradient elution with ceramic hydroxyapatite. (2020) (1)
- Toolboxes for a standardised and systematic study of glycans (2014) (1)
- Informatics and Analytical Tools for Glycan Analysis and the Development of Biotherapeutics (2015) (1)
- Separations by Continuous Annular Chromatography (1991) (1)
- Cyclic Fixed-Bed Sorption Processes for Bioseparations — Design Aspects (1991) (1)
- Chapter 5. Adsorption Equilibria (2010) (1)
- Diffusion with instantaneous reaction in a drop with continuous‐phase resistance (1989) (1)
- Preparation and characterization of agarose-encapsulated ceramic hydroxyapatite particles for flow-through chromatography (2022) (1)
- Rapid and Sensitive Detection of the Interaction of Human Papillomavirus Virus‐Like Particles with Yeast Whole Cell RNA Using Biolayer Interferometry (2018) (1)
- Cover Image, Volume 93, Issue 7 (2018) (0)
- Effect of Column Number in Ion Exchange Multicolumn System for L-Lysine Purification (2008) (0)
- Meeting report: 24th International symposium, exhibit and workshops on preparative and process chromatography - PREP2011. (2011) (0)
- In memoriam—Elmer L. Gaden, Jr. (2012) (0)
- PROCEDE DE SYNTHESE D'INHIBITEURS DE LA HMG-CoA REDUCTASE (1994) (0)
- Preparative-scale proteins seperations by continuous annular chromatography (1989) (0)
- Diffusion mechanisms for protein adsorption in macroporous and polymer-grafted ion exchangers (2012) (0)
- Protein adsorption on core‐shell resins for flow‐through purifications: Effect of protein molecular size, shape, and salt concentration (2022) (0)
- Dynamics of Chromatography Columns (2010) (0)
- Ion Exchange Equilibrium and Transport of Biologicals in Resins for Pharmaceutical Processing (1992) (0)
- Theory of Two-Component Irreversible Adsorption with Pore Diffusion Control (2022) (0)
- Laboratory and Process Columns and Equipment (2010) (0)
- Lysine Adsorption on Cation Exchange Resin. IV. Temperature Effects on Equilibrium and Kinetics in Batch and Column Systems (2008) (0)
- Minimizing On-Column Monoclonal Antibody Aggregate Formation (2017) (0)
- SYNTHETIC METHODS FOR INHIBITORS OF HMG-CoA REDUCTASE (1994) (0)
- Crystal structures of thiocyanate polyamine copper(II) complexes. Part VI. Di-(3-aminopropyl)aminebis(isothiocyanato)copper(II) (1974) (0)
- DYNAMICS OF ADSORPTIVE REACTOR WITH A BIMOLECULAR REACTION (1999) (0)
- Correspondence between ultrasonography and histological features in a single thyroid nodule with coexisting follicular adenoma and papillary carcinoma. (2008) (0)
- High-throughput Workflow for Glycan Profiling and Characterisation (2014) (0)
- 1 Downstream Processing of Biotechnology Products (2010) (0)
- Large-scale separation of amino acids by continuous displacement chromatography (1989) (0)
- Development and application of novel virtual High Throughput Screening (vHTS) Technologies (2008) (0)
- Giorgio Carta: bioseparations. (2006) (0)
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