Giorgio Racagni
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Giorgio Racagni's Degrees
- PhD Neuroscience University of Milan
- Masters Biology University of Milan
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(Suggest an Edit or Addition)Giorgio Racagni's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes (1994) (474)
- Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus (2002) (437)
- Treatment resistant depression: methodological overview and operational criteria (1999) (395)
- Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity (2014) (377)
- Peroxynitrite Inhibits Glutamate Transporter Subtypes (*) (1996) (376)
- Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions (2004) (328)
- Guidelines for depot antipsychotic treatment in schizophrenia (1998) (312)
- Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview (2006) (306)
- Neuronal plasticity: A link between stress and mood disorders (2009) (288)
- Acute Stress Increases Depolarization-Evoked Glutamate Release in the Rat Prefrontal/Frontal Cortex: The Dampening Action of Antidepressants (2010) (263)
- Posttraumatic Stress Disorder: Diagnosis and Epidemiology, Comorbidity and Social Consequences, Biology and Treatment (2001) (255)
- Projections of substance P containing neurons from neostriatum to substantia nigra (1977) (254)
- Chronic Antidepressants Reduce Depolarization-Evoked Glutamate Release and Protein Interactions Favoring Formation of SNARE Complex in Hippocampus (2005) (228)
- Stress during development: Impact on neuroplasticity and relevance to psychopathology (2007) (214)
- Current pharmacological treatments for COVID‐19: What's next? (2020) (211)
- Neuronal and Glial Glutamate Transporters Possess an SH‐based Redox Regulatory Mechanism (1997) (193)
- The role of noradrenaline and selective noradrenaline reuptake inhibition in depression (2002) (189)
- Selective Phosphorylation of Nuclear CREB by Fluoxetine is Linked to Activation of CaM Kinase IV and MAP Kinase Cascades (2004) (186)
- New Insights into the Biology of Schizophrenia through the Mechanism of Action of Clozapine (1995) (185)
- Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. (1994) (178)
- International Union of Basic and Clinical Pharmacology CIV: The Neurobiology of Treatment-resistant Depression: From Antidepressant Classifications to Novel Pharmacological Targets (2018) (173)
- Choline acetyltransferase activity and mass fragmentographic measurement of acetylcholine in specific nuclei and tracts of rat brain (1975) (160)
- Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment (2013) (160)
- Social phobia: diagnosis and epidemiology, neurobiology and pharmacology, comorbidity and treatment. (2000) (153)
- Modulation of synaptic plasticity by stress and antidepressants. (2002) (147)
- Mass fragmentographic measurement of norepinephrine dopamine, serotonin and acetylcholine in seven discrete nuclei of the rat tel-diencephalon. (1974) (146)
- In vivo inhibition of striatal acetylcholine turnover by L-DOPA, apomorphine and (+)-amphetamine (1975) (145)
- Effects of atypical antipsychotics on the inflammatory response system in schizophrenic patients resistant to treatment with typical neuroleptics (2000) (144)
- Cellular and molecular mechanisms in the long-term action of antidepressants. (2008) (141)
- GABAergic control of anterior pituitary hormone secretion. (1982) (136)
- Corticostriatal brain‐derived neurotrophic factor dysregulation in adult rats following prenatal stress (2004) (130)
- Chronic Duloxetine Treatment Induces Specific Changes in the Expression of BDNF Transcripts and in the Subcellular Localization of the Neurotrophin Protein (2007) (126)
- Arachidonic Acid Inhibits a Purified and Reconstituted Glutamate Transporter Directly from the Water Phase and Not via the Phospholipid Membrane (*) (1995) (125)
- Mode of action of agomelatine: Synergy between melatonergic and 5-HT2C receptors (2011) (125)
- Typical and atypical antidepressants. Molecular mechanisms. (1982) (118)
- The Competitive Transport Inhibitor L‐trans‐pyrrolidine‐2,4‐dicarboxylate Triggers Excitotoxicity in Rat Cortical Neuron‐Astrocyte Co‐cultures via Glutamate Release rather than Uptake Inhibition (1996) (117)
- Second Messenger‐Regulated Protein Kinases in the Brain (2000) (117)
- Stress, glucocorticoids and glutamate release: Effects of antidepressant drugs (2011) (116)
- Chronic treatment with fluoxetine up-regulates cellular BDNF mRNA expression in rat dopaminergic regions. (2006) (112)
- Modulation of fibroblast growth factor-2 by stress and corticosteroids: from developmental events to adult brain plasticity (2001) (112)
- Chronic fluoxetine administration inhibits extracellular signal‐regulated kinase 1/2 phosphorylation in rat brain (2005) (111)
- Fluoxetine and olanzapine have synergistic effects in the modulation of fibroblast growth factor 2 expression within the rat brain (2004) (111)
- Noradrenaline in mood and anxiety disorders: basic and clinical studies (2003) (109)
- Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans (2010) (108)
- Involvement of brain cholinergic mechanisms in the action of chlorpromazine (1974) (108)
- Repeated exposure to cocaine differently modulates BDNF mRNA and protein levels in rat striatum and prefrontal cortex (2007) (108)
- Guidelines for depot antipsychotic treatment in schizophrenia. European Neuropsychopharmacology Consensus Conference in Siena, Italy. (1998) (106)
- Stress and corticosterone increase the readily releasable pool of glutamate vesicles in synaptic terminals of prefrontal and frontal cortex (2014) (105)
- Measurement of acetylcholine turnover rate in discrete areas of rat brain. (1974) (100)
- Regulation of Editing and Expression of Glutamate α-Amino-Propionic-Acid (AMPA)/Kainate Receptors by Antidepressant Drugs (2006) (98)
- cAMP-dependent phosphorylation of soluble and crude microtubule fractions of rat cerebral cortex after prolonged desmethylimipramine treatment. (1989) (98)
- Modulation of the inflammatory response in rats chronically treated with the antidepressant agomelatine (2012) (95)
- Dual y-Aminobutyric Acid Control of Prolactin Secretion in the Rat* (1979) (94)
- Ultrasonic vocalization in response to unavoidable aversive stimuli in rats: effects of benzodiazepines. (1988) (93)
- Stress-Induced Changes of Hippocampal NMDA Receptors: Modulation by Duloxetine Treatment (2012) (89)
- Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro. (1995) (89)
- Differential sensitivity to morphine-induced analgesia and motor activity in two inbred strains of mice: behavioral and biochemical correlations. (1979) (81)
- BDNF gene expression is reduced in the frontal cortex of dopamine transporter knockout mice (2003) (81)
- Effect of antipsychotic drugs on brain‐derived neurotrophic factor expression under reduced N‐methyl‐D‐aspartate receptor activity (2003) (81)
- Regulation of NMDA receptor subunit mRNA expression in the rat brain during postnatal development. (1994) (80)
- Reactive Oxygen Species Inhibit High‐Affinity Glutamate Uptake: Molecular Mechanism and Neuropathological Implications (1994) (80)
- In vivo actions of clozapine and haloperidol on the turnover rate of acetylcholine in rat striatum. (1976) (79)
- Developmental and stress-related changes of neurotrophic factor gene expression in an animal model of schizophrenia (2001) (78)
- GABA of CNS origin in the rat anterior pituitary inhibits prolactin secretion (1979) (78)
- Reduced neuroplasticity in aged rats: a role for the neurotrophin brain-derived neurotrophic factor (2013) (78)
- cAMP binding proteins in the rat cerebral cortex after administration of selective 5-HT and NE reuptake blockers with antidepressant activity. (1991) (78)
- Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome. (1996) (77)
- The pharmacological properties of antidepressants (2010) (76)
- Pharmacokinetics interactions of monoclonal antibodies. (2016) (76)
- Acute Stress Responsiveness of the Neurotrophin BDNF in the Rat Hippocampus is Modulated by Chronic Treatment with the Antidepressant Duloxetine (2009) (75)
- Pharmacokinetic drug interactions of the non‐vitamin K antagonist oral anticoagulants (NOACs) (2018) (74)
- Direct and indirect costs of schizophrenia in community psychiatric services in Italy: The GISIES study (2000) (73)
- An analysis at synaptic level of the morphine action in striatum and N. accumbens: dopamine and acetylcholine interactions. (1975) (73)
- Regulation of NMDA receptor subunit messenger RNA levels in the rat brain following acute and chronic exposure to antipsychotic drugs. (1997) (73)
- PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. (1979) (72)
- Inhibition of nitric oxide synthase dramatically potentiates seizures induced by kainic acid and pilocarpine in rats (1995) (72)
- Effect of reboxetine, a new antidepressant drug, on the central noradrenergic system: Behavioural and biochemical studies (1989) (72)
- Temporal sequence of changes in central noradrenergic system of rat after prolonged antidepressant treatment: Receptor desensitization and neurotransmitter interactions (1983) (71)
- Antidepressant treatments and function of glutamate ionotropic receptors mediating amine release in hippocampus (2007) (71)
- Remodelling by early-life stress of NMDA receptor-dependent synaptic plasticity in a gene-environment rat model of depression. (2009) (71)
- Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801 (2004) (70)
- Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis (2011) (70)
- Action of opiates, antipsychotics, amphetamine and apomorphine on dopamine receptors in rat striatum: in vivo changes of 3′,5′-cyclic amp content and acetylcholine turnover rate (1975) (70)
- Antipsychotic drug actions on gene modulation and signaling mechanisms. (2009) (70)
- cAMP cascade leads to Ras activation in cortical neurons. (2000) (69)
- Stress-induced anhedonia is associated with the activation of the inflammatory system in the rat brain: Restorative effect of pharmacological intervention. (2016) (68)
- Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine (2011) (68)
- Depression and Sleep Disorders: Clinical Relevance, Economic Burden and Pharmacological Treatment (2000) (66)
- Prenatal stress alters glutamatergic system responsiveness in adult rat prefrontal cortex (2009) (65)
- Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment. (2000) (65)
- Effects of acute and chronic morphine on regional rat brain acetylcholine turnover rate. (1974) (65)
- Prophylactic Use of Anticholinergics in Patients on Long-Term Neuroleptic Treatment (1990) (65)
- Abnormalities of cyclic adenosine monophosphate signaling in platelets from untreated patients with bipolar disorder. (1999) (65)
- Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration (2010) (64)
- Short- and long-term induction of basic fibroblast growth factor gene expression in rat central nervous system following kainate injection (1994) (63)
- Modulation of BDNF expression by repeated treatment with the novel antipsychotic lurasidone under basal condition and in response to acute stress. (2012) (63)
- Dynamic Regulation of Glutamatergic Postsynaptic Activity in Rat Prefrontal Cortex by Repeated Administration of Antipsychotic Drugs (2008) (63)
- Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants (2009) (62)
- Prenatal stress elicits regionally selective changes in basal FGF-2 gene expression in adulthood and alters the adult response to acute or chronic stress (2005) (62)
- Typical and atypical antidepressants. Clinical practice. (1982) (61)
- Acute Stress Responsiveness of the Neurotrophin BDNF in the Rat Hippocampus is Modulated by Chronic Treatment with the Antidepressant Duloxetine (2009) (60)
- Presynaptic Ca2+/calmodulin-dependent protein kinase II: autophosphorylation and activity increase in the hippocampus after long-term blockade of serotonin reuptake. (1995) (60)
- Current pharmacological treatments for COVID-19: what’s next? (2020) (60)
- Long-Term Duloxetine Treatment Normalizes Altered Brain-Derived Neurotrophic Factor Expression in Serotonin Transporter Knockout Rats through the Modulation of Specific Neurotrophin Isoforms (2010) (59)
- Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways (2010) (59)
- A role for the arachidonic acid cascade in fast synaptic modulation: ion channels and transmitter uptake systems as target proteins. (1992) (59)
- Sub-chronic exposure to atomoxetine up-regulates BDNF expression and signalling in the brain of adolescent spontaneously hypertensive rats: comparison with methylphenidate. (2010) (59)
- Chronic antidepressant treatments induce a time-dependent up-regulation of AMPA receptor subunit protein levels (2011) (58)
- NSAIDs in patients with viral infections, including Covid-19: Victims or perpetrators? (2020) (57)
- Ultrasonic vocalization in rat pups: effects of early postnatal exposure to haloperidol. (1986) (57)
- Opposite Regulation of Basic Fibroblast Growth Factor and Nerve Growth Factor Gene Expression in Rat Cortical Astrocytes Following Dexamethasone Treatment (1995) (56)
- Depression-prone mice with reduced glucocorticoid receptor expression display an altered stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated cytoskeleton-associated protein (2010) (56)
- Modulation of glutamate receptors in response to the novel antipsychotic olanzapine in rats (2001) (55)
- COVID-19 Vaccination in Pregnancy, Paediatrics, Immunocompromised Patients, and Persons with History of Allergy or Prior SARS-CoV-2 Infection: Overview of Current Recommendations and Pre- and Post-Marketing Evidence for Vaccine Efficacy and Safety (2021) (55)
- Effect of progesterone, testosterone and their 5α-reduced metabolites on GFAP gene expression in type 1 astrocytes (1996) (54)
- Constant rate infusion of deuterated phosphorylcholine to measure the effects of morphine on acetylcholine turnover rate in specific nuclei of rat brain (1977) (54)
- Abnormalities of cAMP-dependent endogenous phosphorylation in platelets from patients with bipolar disorder. (1995) (54)
- Perspective: Improving Nutritional Guidelines for Sustainable Health Policies: Current Status and Perspectives (2017) (54)
- New biochemical hypotheses on the mechanism of action of antidepressant drugs: cAMP-dependent phosphorylation system. (1992) (53)
- Synergistic mechanisms involved in the antidepressant effects of agomelatine (2012) (53)
- Early-life stress and antidepressant treatment involve synaptic signaling and Erk kinases in a gene-environment model of depression. (2010) (52)
- The interaction between the internal clock and antidepressant efficacy (2007) (52)
- Emerging role of the FGF system in psychiatric disorders. (2005) (52)
- GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone (2010) (52)
- Striatal increase of neurotrophic factors as a mechanism of nicotine protection in experimental parkinsonism (2005) (52)
- Chronic Antidepressants Induce Redistribution and Differential Activation of αCaM Kinase II between Presynaptic Compartments (2007) (51)
- Prolonged abstinence from developmental cocaine exposure dysregulates BDNF and its signaling network in the medial prefrontal cortex of adult rats. (2014) (51)
- Cyclic AMP-dependent regulation of fibroblast growth factor-2 messenger RNA levels in rat cortical astrocytes: comparison with fibroblast growth factor-1 and ciliary neurotrophic factor. (1996) (50)
- Regulation of Ionotropic Glutamate Receptors in the Rat Brain in Response to the Atypical Antipsychotic Seroquel (Quetiapine Fumarate) (1999) (50)
- Correlation between analgesia and the decrease of acetylcholine turnover rate in cortex and hippocampus elicited by morphine, meperidine, viminol R2 and azidomorphine. (1976) (48)
- Protein kinase A and Rap1 levels in platelets of untreated patients with major depression (2001) (48)
- Consensus conference on the methodology of clinical trials of antidepressants, Zurich, march 1988: report of the consensus committee (1989) (48)
- Repeated stress prevents cocaine-induced activation of BDNF signaling in rat prefrontal cortex (2009) (47)
- Functional interaction between rat substantia nigra and striatum: GABA and dopamine interrelation (1977) (46)
- In vivo studies on central noradrenergic synaptic mechanisms after acute and chronic antidepressant drug treatment: biochemical and behavioral comparison. (1982) (46)
- Corticostriatal Up-Regulation of Activity-Regulated Cytoskeletal-Associated Protein Expression after Repeated Exposure to Cocaine (2006) (46)
- Region-specific effects on BDNF expression after contingent or non-contingent cocaine i.v. self-administration in rats. (2013) (45)
- Early induction of CREB activation and CREB-regulating signalling by antidepressants. (2009) (44)
- Genotype-dependent sensitivity to morphine: dopamine involvement in morphine-induced running in the mouse (1976) (44)
- Selective modulation of fibroblast growth factor-2 expression in the rat brain by the atypical antipsychotic clozapine (1999) (43)
- Critical issues in the treatment of affective disorders (1995) (43)
- Synaptoproteomics of learned helpless rats involve energy metabolism and cellular remodeling pathways in depressive-like behavior and antidepressant response (2011) (42)
- Dysthymia: clinical picture, extent of overlap with chronic fatigue syndrome, neuropharmacological considerations, and new therapeutic vistas. (1999) (42)
- Consensus on the Use of Substituted Benzamides in Psychiatric Patients (2004) (42)
- Mechanisms subserving the stimulatory and inhibitory components of gamma-aminobutyric acid-ergic control of prolactin secretion in the rat. (1981) (41)
- Modulation of opioid system in C57 mice after repeated treatment with morphine and naloxone: biochemical and behavioral correlates. (1984) (41)
- The measurement of acetylcholine turnover rate in brain structures (1976) (40)
- Antidepressants activate CaMKII in neuron cell body by Thr286 phosphorylation (2004) (40)
- Rationale for the development of noradrenaline reuptake inhibitors (1998) (40)
- Modulation of neuronal plasticity following chronic concomitant administration of the novel antipsychotic lurasidone with the mood stabilizer valproic acid (2013) (39)
- Transynaptic mechanisms in the action of antidepressant drugs (1984) (39)
- Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment. (1988) (39)
- Antidepressant Treatments Change 5-HT2C Receptor mRNA Expression in Rat Prefrontal/Frontal Cortex and Hippocampus (2011) (39)
- Dynamic regulation of fibroblast growth factor 2 (FGF‐2) gene expression in the rat brain following single and repeated cocaine administration (2006) (39)
- Lack of Serotonin Transporter Alters BDNF Expression in the Rat Brain During Early Postnatal Development (2013) (39)
- Single session of cocaine intravenous self-administration shapes goal-oriented behaviours and up-regulates Arc mRNA levels in rat medial prefrontal cortex. (2009) (39)
- Physiology to functionality: the brain and neurotransmitter activity. (1999) (38)
- Selective regulation of presynaptic Calcium/Calmodulin-Dependent protein kinase II by psychotropic drugs (2003) (38)
- Correction: Acute Stress Increases Depolarization-Evoked Glutamate Release in the Rat Prefrontal/Frontal Cortex: The Dampening Action of Antidepressants (2010) (37)
- beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. (1996) (37)
- GABA and endocrine function (1986) (37)
- Behavioural and neurochemical changes in offspring of rats exposed to methyl mercury during gestation. (1984) (37)
- Exposure to early life stress regulates Bdnf expression in SERT mutant rats in an anatomically selective fashion (2015) (37)
- Long-term blockade of serotonin reuptake affects synaptotagmin phosphorylation in the hippocampus. (1997) (37)
- Abnormal Levels of cAMP-dependent Protein Kinase Regulatory Subunits in Platelets from Schizophrenic Patients (2000) (36)
- Analgesia and motor activity elicited by morphine and enkephalins in two inbred strains of mice (1978) (36)
- Long-Term Exposure to the Atypical Antipsychotic Olanzapine Differently Up-Regulates Extracellular Signal-Regulated Kinases 1 and 2 Phosphorylation in Subcellular Compartments of Rat Prefrontal Cortex (2006) (36)
- Effects of Lithium on cAMP-Dependent Protein Kinase in Rat Brain (1998) (35)
- Developmental Influence of the Serotonin Transporter on the Expression of Npas4 and GABAergic Markers: Modulation by Antidepressant Treatment (2012) (35)
- Pentobarbital and in vivo turnover rate of acetylcholine in mouse brain and in regions of rat brain. (1975) (35)
- Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction (1994) (35)
- Interaction of SCH 23390, a D-1-selective antagonist, with the anterior pituitary D-2 receptors and prolactin secretion in the rat. (1985) (35)
- cAMP-dependent phosphorylation system after short and long-term administration of moclobemide. (1998) (34)
- Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats. (2013) (34)
- Direct and indirect costs of schizophrenia in community psychiatric services in Italy. The GISIES study. Interdisciplinary Study Group on the Economic Impact of Schizophrenia. (2000) (34)
- Association between promoter polymorphic haplotypes of interleukin-10 gene and schizophrenia (2001) (34)
- Prolactin-inhibiting activity of gamma-aminobutyric acid-mimetic drugs in the male rat (1978) (33)
- Pharmacological characterization of BDNF promoters I, II and IV reveals that serotonin and norepinephrine input is sufficient for transcription activation. (2014) (33)
- Age-related variations in relative abundance of alternative spliced D2 receptor mRNAs in brain areas of two rat strains. (1992) (33)
- Differential effects of lithium on platelet protein phosphorylation in bipolar patients and healthy subjects (1997) (33)
- Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells (2008) (33)
- Anxious depression : assessment and treatment (1987) (33)
- Chronic treatment with agomelatine or venlafaxine reduces depolarization-evoked glutamate release from hippocampal synaptosomes (2013) (32)
- Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors (2010) (32)
- Neurotrophic Factors in Neurodegenerative Disorders (2008) (32)
- Stress rapidly dysregulates the glutamatergic synapse in the prefrontal cortex of cocaine‐withdrawn adolescent rats (2015) (32)
- Hypoglycemia-activated K+ channels in hippocampal neurons (1992) (31)
- Association Study of –1727 A/T, –50 C/T and (CAA)n Repeat GSK-3β Gene Polymorphisms with Schizophrenia (2004) (31)
- Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder. (2000) (31)
- Age-related changes in 5HT uptake and [3H]imipramine binding sites in rat cerebral cortex. (1985) (31)
- Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice. (2011) (31)
- Effects of an extract of Ginkgo biloba on noradrenergic systems of rat cerebral cortex. (1985) (31)
- Renin-Angiotensin System and Coronavirus Disease 2019: A Narrative Review (2020) (31)
- Serine/threonine kinases as molecular targets of antidepressants: implications for pharmacological treatment and pathophysiology of affective disorders. (2001) (31)
- Therapeutic strategies to fight COVID‐19: Which is the status artis? (2021) (30)
- Basal and stress-induced modulation of activity-regulated cytoskeletal associated protein (Arc) in the rat brain following duloxetine treatment (2008) (30)
- Allelic Variation in the Human Prodynorphin Gene Promoter and Schizophrenia (2002) (30)
- Differences in the action of various drugs on striatal acetylcholine and choline content in rats killed by decapitation or microwave radiation (1976) (30)
- Dopaminergic D2 receptor activation modulates FGF‐2 gene expression in rat prefrontal cortex and hippocampus (2003) (30)
- Medication-Induced Akathisia with Newly Approved Antipsychotics in Patients with a Severe Mental Illness: A Systematic Review and Meta-Analysis (2019) (29)
- Single exposure to erythropoietin modulates Nerve Growth Factor expression in the spinal cord following traumatic injury: comparison with methylprednisolone. (2008) (29)
- Use of microwave techniques to inactivate brain enzymes rapidly. (1982) (28)
- Antipsychotic drugs modulate Arc expression in the rat brain (2009) (28)
- Role of central nervous system-derived or circulating gamma-aminobutyric acid on prolactin secretion in the rat. (1981) (28)
- 3-Methoxytyramine and different neuroleptics: dissociation from HVA and DOPAC. (1978) (28)
- Depression and cardiovascular risk—association among Beck Depression Inventory, PCSK9 levels and insulin resistance (2020) (28)
- Daily fluctuations in the activity of the tuberoinfundibular GABAergic system and plasma prolactin levels. (1984) (27)
- Ultrasonic vocalization in rat pups: Effects of early postnatal exposure to SCH 23390 (a DA1-receptor antagonist) and sulpiride (a DA2-receptor antagonist) (1987) (27)
- Repeated aripiprazole treatment regulates Bdnf, Arc and Npas4 expression under basal condition as well as after an acute swim stress in the rat brain. (2014) (27)
- Chronic phencyclidine administration reduces the expression and editing of specific glutamate receptors in rat prefrontal cortex (2007) (27)
- Biochemical and functional aspects on the control of prolactin release by the hypothalamo-pituitary GABAergic system (1989) (27)
- Chronic treatments in neuropsychiatry (1985) (27)
- Acute Footshock Stress Induces Time-Dependent Modifications of AMPA/NMDA Protein Expression and AMPA Phosphorylation (2016) (27)
- Kappa-opioid receptor changes and neurophysiological alterations during cerebral ischemia in rabbits. (1990) (27)
- Repeated electroconvulsive shock (ECS) alters the phosphorylation of glutamate receptor subunits in the rat hippocampus. (2010) (26)
- Inhibitory effect of lithium on cAMP dependent phosphorylation system. (1996) (26)
- Determination of dopamine in the anterior pituitary as an index of tubero-infundibular dopaminergic function (1980) (26)
- EFFECT OF SOME TRICYCLIC AND NONTRICYCLIC ANTIDEPRESSANTS ON [3H]IMIPRAMINE BINDING AND SEROTONIN UPTAKE IN RAT CEREBRAL CORTEX AFTER PROLONGED TREATMENT (1987) (26)
- Short-term withdrawal from developmental exposure to cocaine activates the glucocorticoid receptor and alters spine dynamics (2015) (26)
- Effect of Different Photoperiod Exposure on [3H]Imipramine Binding and Serotonin Uptake in the Rat Brain (1989) (26)
- cAMP signaling pathway in depressed patients with psychotic features (2002) (25)
- Ethanolamine-O-sulfate enhances gamma-aminobutyric acid secretion into hypophysial portal blood and lowers serum prolactin concentrations. (1983) (25)
- Reduced CREB phosphorylation after chronic lithium treatment is associated with down-regulation of CaM kinase IV in rat hippocampus. (2007) (24)
- Ultrasonic vocalization in rat pups as a marker of behavioral development: an investigation of the effects of drugs influencing brain opioid system. (1988) (24)
- Developmental Influence of the Serotonin Transporter on the Expression of Npas4 and GABAergic Markers: Modulation by Antidepressant Treatment (2012) (24)
- Adrenalectomy reduces FGF-1 and FGF-2 gene expression in specific rat brain regions and differently affects their induction by seizures. (1995) (24)
- A new nomenclature for classifying psychotropic drugs. (2017) (23)
- Altered cAMP-dependent protein kinase A in platelets of patients with obsessive-compulsive disorder. (2000) (23)
- L‐Deprenyl potentiates cAMP‐induced elevation of FGF‐2 mRNA levels in rat cortical astrocytes (1997) (23)
- Regulation of prolactin secretion during suckling: involvement of the hypothalamo-pituitary GABAergic system (1984) (23)
- Portal-Systemic Encephalopathy in Dogs: Changes in Brain GABA Receptors and Neurochemical Correlates (1984) (23)
- Accumulation of cGMP in striatum of rats injected with narcotic analgesics: antagonism by naltrexone (1976) (23)
- Protein kinase A activity in platelets from patients with bipolar disorder. (2003) (23)
- Should Patients Receiving ACE Inhibitors or Angiotensin Receptor Blockers be Switched to Other Antihypertensive Drugs to Prevent or Improve Prognosis of Novel Coronavirus Disease 2019 (COVID-19)? (2020) (22)
- Differential regulation of FGF-2 and FGFR-1 in rat cortical astrocytes by dexamethasone and isoproterenol. (1998) (22)
- Reduction of Corticostriatal Glutamatergic Fibers in Basic Fibroblast Growth Factor Deficient Mice is Associated with Hyperactivity and Enhanced Dopaminergic Transmission (2007) (22)
- Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes. (1999) (22)
- Acute spinal cord injury reduces brain derived neurotrohic factor expression in rat hippocampus (2009) (22)
- The AMPA receptor potentiator Org 26576 modulates stress-induced transcription of BDNF isoforms in rat hippocampus. (2012) (22)
- Prolactin in cerebrospinal fluid increases the synthesis and release of hypothalamic gamma-aminobutyric acid. (1985) (21)
- Ontogenetic study of [3H]imipramine binding sites and serotonin uptake system: indication of possible interdependence. (1982) (21)
- Altered expression and modulation of activity-regulated cytoskeletal associated protein (Arc) in serotonin transporter knockout rats (2009) (21)
- The role of dopamine D3 receptors in the mechanism of action of cariprazine (2019) (21)
- Chronic cocaine administration modulates the expression of transcription factors involved in midbrain dopaminergic neuron function (2007) (21)
- Behavioural changes after acute and chronic administration of typical and atypical antidepressants in rats: Interactions with reserpine (1983) (21)
- Non‐insulin anti‐diabetic drugs: An update on pharmacological interactions (2017) (20)
- AMPA GluR‐A receptor subunit mediates hippocampal responsiveness in mice exposed to stress (2010) (20)
- Centella asiatica L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex (2020) (20)
- Stress and cocaine interact to modulate basic fibroblast growth factor (FGF-2) expression in rat brain (2008) (20)
- Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. (2014) (20)
- Developmental Exposure to Cocaine Dynamically Dysregulates Cortical Arc/Arg3.1 Modulation in Response to a Challenge (2017) (19)
- Prolactin control by the tubero-infundibular gabaergic system: role of anterior pituitary GABA receptors (1984) (19)
- Modifications in Brain CaM Kinase II after Long-Term Treatment with Desmethylimipramine (2001) (19)
- Apomorphine-induced inhibition of striatal dopamine release: role of dopaminergic receptors in substantia nigra (1978) (18)
- Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex (1993) (18)
- Chronic Mild Stress Modulates Activity-Dependent Transcription of BDNF in Rat Hippocampal Slices (2015) (18)
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- Short communication Acute and chronic changes in K q -induced depolarization alter NMDA and nNOS gene expression in cultured cerebellar granule cells (1996) (0)
- K-opioid receptors in an experimental model of cerebral ischemia in rabbit (1988) (0)
- Long-Term Abstinence from Developmental Cocaine Exposure Alters Arc/Arg3.1 Modulation in the Rat Medial Prefrontal Cortex (2014) (0)
- P.1.059 The presynaptic release apparatus: A main site in the mechanism of action of psychotropic drugs (1996) (0)
- Behavioural responsiveness to muscimol and apomorphine 2 months after prolonged treatment with estradiol in rats (2004) (0)
- Modification of transducing and intracellular mechanisms in rat cerebral cortex after chronic treatment with antidepressant drugs (1990) (0)
- Antidepressant treatment restores stress-induced anhedonia and the associated activation of the inflammatory system in the rat brain (2015) (0)
- Differential regulation of FGF-2 gene expression by MK-801 (dizocilpine) (2000) (0)
- O-21-2 Long-term changes induced by anti-depressant drugs in the presynaptic release machinery (1996) (0)
- S.20.03 Isoform expression and intracellular trafficking of BDNF following stress and antidepressant drug treatment (2009) (0)
- Chronobiological Studies of Serotonin Uptake Complex: Relevance to Antidepressant Action (1990) (0)
- ERK 1/2 and CaMKII: two novel targets for antipsychotic therapy? (2006) (0)
- P.3.d.002 Modulation of neurotrophic mechanisms after chronic treatment with the novel antipsychotic lurasidone in rats (2011) (0)
- S-33-5 Lithium effects on protein phosphorylation in bipolar and healthy subjects (1996) (0)
- Short Communication f3PP and Tau Interaction A Possible Link between Amyloid and Neurofibrillary Tangles in Alzheimer's Disease (2007) (0)
- Cerebrovascular disease and k-opioid receptors in the rabbit. (1990) (0)
- Stress responsiveness is altered in AMPA receptor subunit 1 (GluR−A) knockout mice (2010) (0)
- Receptor mediated responses and intracellular mechanisms after antidepressant treatment (1988) (0)
- Increase of bFGF mRNA levels in rat central nervous system following convulsive seizures (1992) (0)
- S.08.02 Role of Arc/Arg3.1 in the actions of psychostimulant drugs (2009) (0)
- 14:15 ONTOGENY OF COGNITIVE IMPAIRMENT FOLLOWING PRENATAL INFECTION (2012) (0)
- P.1.014 Ketamine modulates glutamate release, BDNF trafficking and dendrite morphology in rats vulnerable to chronic mild stress (2017) (0)
- S.17.04 Regulation of glutamate receptor gene expression in response to antipsychotic drug treatment (1997) (0)
- Developmental Exposure to Cocaine Dynamically Dysregulates Cortical Arc/Arg3.1 Modulation in Response to a Challenge (2016) (0)
- 1256 – THE EFFECT OF CLOZAPINE AND ACETYLCHOLINE TURNOVER RATE IN RAT STRIATUM (1977) (0)
- P.2.016 Investigating stress resilience and susceptibility: impact of lipopolysaccharide on the rat brain (2017) (0)
- Expression and functional role of mGluR3 in substantia nigra neurons (1996) (0)
- MODULATION OF BDNF EXPRESSION AFTER CHRONIC TREATMENT WITH THE NOVEL ANTIPSYCHOTIC LURASIDONE IN RATS : BASAL CHANGES AND STRESS RESPONSIVENESS (2011) (0)
- S.4.08 Temporal and anatomical characterization of stress-related changes on BDNF expression in the rat central nervous system (2004) (0)
- METHYLPHENIDATE AND ATOMOXETINE AFFECT BDNF EXPRESSION IN THE BRAIN OF SPONTANEOUS HYPERTENSIVE RATS. (2009) (0)
- Acute and chronic changes in K q-induced depolarization alter NMDA and nNOS gene expression in cultured cerebellar granule cells (1996) (0)
- P.2.d.024 Modulation of the neurotrophin BDNF in serotonin transporter mutant rats (2009) (0)
- P.1.02 Effects of stress and antidepressants on glutamate release and presynaptic molecular mechanisms (2008) (0)
- O-21-7 Phosphorylation by Ca2+/Calmodulin-dependent protein kinase II. Effect on Ca2+/Phospholipid binding (1996) (0)
- Mental Disorders in the Elderly: New Therapeutic Approaches: Rome, April 1997 (1998) (0)
- Establishing patient safety monitoring in the benefit-risk paradigm for off-label and emergency use of medications for COVID-19: A pharmacovigilance perspective (2022) (0)
- Protein phosphorylation as intracellular target in the action of MAO-A inhibitors and other antidepressants (1993) (0)
- The Role of Learned Pharmacology Societies during the COVID 19 epidemic experience of the Italian Society of Pharmacology (2020) (0)
- T he protein kinase A in platelets from patients with panic disorder (2015) (0)
- P-11-24 Regulation of FGF-1 and FGF-2 gene expression in primary culture of rat astrocytes following beta adrenergic receptor activation (1995) (0)
- Effect of novel mGluR antagonists on signal transduction in mesencephalic and striatal neurons in vitro (1996) (0)
- The novel antidepressant agomelatine reduces depolarization-evoked release of glutamate and SNARE complex in rat hippocampus (2007) (0)
- Pharmacodynamics and pharmacokinetics as a possible causality in resistant depression (1998) (0)
- The Role of Neurochemistry in Behavioural Teratology and Toxicology (1988) (0)
- [Markers of brain tumors]. (1984) (0)
- Evaluation of neuroinflammation in an animal model of depression : effect of antidepressant treatment (2015) (0)
- Modulation of presynaptic release machinery by typical and typical antidepressants (1998) (0)
- SS01-01 - A New Way To Manage Depression Successfully: Restoring Circadian Rhythms (2010) (0)
- Editorial Board (2000) (0)
- P.4.e.004 Acute ketamine restores deficits in glutamate release and related molecular mechanisms induced by chronic mild stress in vulnerable rats (2016) (0)
- Behavioral and Biochemical Effects in the Adult Rat After Prolonged Postnatal Administration of Cataleptogenic and Non-cataleptogenic Neuroleptics (1983) (0)
- Longitudinal changes of plasma HVA and 5-HIAA levels in schizophrenic patients resistant to neuroleptics (1999) (0)
- P-2-16 Changes in the subcellular distribution of cAMP receptors after chronic treatment with fluvoxamine and paroxetine (1995) (0)
- Modulation of 5 hydroxytryptamine uptake and tritiated imipramine recognition sites during aging (1985) (0)
- cAMP-and Ca2+/Calmodulin-Dependent Protein Phosphorylation in the Action of Antidepressant Drugs: Early Action of Venlafaxine (1997) (0)
- Agomelatine Treatment Induces Early and Time- dependent Modulation of Rat Hippocampal MiRNome (2013) (0)
- Chronic antidepressants block the increase in depolarization-evoked release of glutamate induced by acute stress (2008) (0)
- MA Riva cytoskeleton-associated protein stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated Depression-prone mice with reduced glucocorticoid receptor expression display an altered (2010) (0)
- Faculty Opinions recommendation of PCSK9 deficiency reduces insulin secretion and promotes glucose intolerance: the role of the low-density lipoprotein receptor. (2019) (0)
- Functional proteomic analysis of an animal model of depression combining genetic vulnerability and environmental stress (2006) (0)
- Regulation of NMDA Receptor Expression in Response to Typical and Atypical Antipsychotics (1998) (0)
- C.12.02 The interaction between the internal clock and antidepressant efficacy (2007) (0)
- A single exposure to cocaine during development elicits regionally-selective changes in basal basic Fibroblast Growth Factor (FGF-2) gene expression and alters the trophic response to a second injection (2014) (0)
- The presynaptic function as target for antidepressants (2000) (0)
- Role of protein phosphorylation in bipolar illness: 12.5 (1995) (0)
- P.1.g.029 Acute stress increases the readily releasable pool of glutamate vesicles in cortical areas (2014) (0)
- P.1.060 Pharmacology of the presynaptic terminal: Modifications induced by antidepressant treatment in the phosphorylation of synaptotagmin and its functional properties (1996) (0)
- P.1.025 Stress at the synapse: the synaptic action of acute behavioural stress and the protective effect of psychiatric drugs (2011) (0)
- P.1.032 Study of the effect of acute stress on glutamate release in prefrontal/frontal cortex of antidepressant treated rats (2010) (0)
- Inhibition of high-affinity glutamate uptake by arachidonic acid and oxygen free radicals: physiopathological significance (1993) (0)
- S-29-5 Tumorigenesis and immune function in a transgenic mouse model of the endocrine changes seen in depression characterized by defective glucocorticoid feedback inhibition and HPA axis hyperactivity (1995) (0)
- Neuroadaptive changes after chronic lurasidone treatment : implication for mood and stress-related disorders (2012) (0)
- Region-specific effects of developmental exposure to cocaine on fibroblast growth factor-2 expression in the rat brain (2016) (0)
- Light-Dark-Related Changes in the Serotonin Uptake Molecular Complex in Rat Brain: Involvement in Antidepressant Action (1989) (0)
- T role of noradrenaline and selective noradrenaline reuptake inhibition in (2002) (0)
- P.1.007 Time-course analysis of hormonal and neuroplastic changes in rats exposed to prenatal stress (2012) (0)
- Adenylate cyclase activity and cyclic AMP content in human central nervous system tumors and in cerebrospinal fluid of patients bearing brain tumors (1986) (0)
- Steady state and dynamics of putative neurotransmitters in tel-diencephalic nuclei: a study using multiple ion detection (1976) (0)
- Modulation of presynaptic glutamate release: Implications for mood disorders and therapy (2006) (0)
- Modulation of neuronal plasticity following chronic concomitant administration of the novel antipsychotic lurasidone with the mood stabilizer valproic acid (2012) (0)
- S.04.04 Temporal and anatomical characterization ofstress-related changes on BDNF expression in the rat central nervous system (2004) (0)
- P.1.027 Modulation of the neurotrophin brain-derived neurotrophic factor in serotonin transporter mutant rats (2011) (0)
- Significance of neurochemical parameters in the preclinical evaluation of neuroleptic drugs. (1979) (0)
- P.1.07 Regulation of brain-derived neurotrophic factor expression by cocaine in rat brain and its modulation by stress (2008) (0)
- 158 Regulation of glutamate receptor gene expression in the rat brain following antipsychotic drug treatment (1997) (0)
- Cyclic GMP inhibition of metabotropic glutamate receptor-induced phosphoinositide hydrolysis in mesencephalic neurons (1996) (0)
- P.1.13 Hyperactivity and altered dopaminergicfunction in FGF-2 knockout mice (2005) (0)
- P.3.d.019 Chronic olanzapine treatment affects intracellular signalling in selected subcellular compartments of rat prefrontal cortex (2006) (0)
- Behavioural and neurochemical changes produced by lefetamine in two inbred strains of mice. (1989) (0)
- Antidepressant and anti-inflammatory properties in the action of agomelatine (2013) (0)
- Dynamic modulation of basic Fibroblast Growth Factor (FGF-2) expression in the rat brain following repeated exposure to cocaine during adolescence (2012) (0)
- Genome-wide analysis of LPS-induced inflammatory response in the rat ventral hippocampus: modulatory activity of chronic treatment with the antidepressant agomelatine (2015) (0)
- Synergy between melatonergic and 5-HT2C receptors in the action of agomelatine : molecular and cellular evidence (2012) (0)
- Microtubules as possible target of camp dependent mechanisms coupled to neurotransmitter receptors (1990) (0)
- S-44-3 Protein phosphorylation as intracellular target of antidepressants (1996) (0)
- P-11-25 Regional regulation of FGF-1 and FGF-2 gene expression by pilocarpine in the rat central nervous system (1995) (0)
- Altered inflammatory responsiveness in serotonin transporter mutant rats (2013) (0)
- S-3-5 Long-term SSRI treatment increases Ca2+/calmodulin phosphorylation of presynaptic proteins: A new site in the mechanism of action of antidepressants (1995) (0)
- Books Received (1998) (0)
- P-11-20 Regulation of NMDA receptor subunit gene expression in rat cerebellar granule cells (1995) (0)
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