Giorgio Sesti
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Physics
Giorgio Sesti's Degrees
- PhD Physics University of Milan
- Masters Physics University of Milan
- Bachelors Physics University of Milan
Why Is Giorgio Sesti Influential?
(Suggest an Edit or Addition)Giorgio Sesti's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6) (2009) (1429)
- Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial (2018) (993)
- Insulin-Dependent Activation of Endothelial Nitric Oxide Synthase Is Impaired by O-Linked Glycosylation Modification of Signaling Proteins in Human Coronary Endothelial Cells (2002) (359)
- Defects of the insulin receptor substrate (IRS) system in human metabolic disorders (2001) (357)
- High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program. (2001) (343)
- Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension. (2005) (281)
- Uric acid and endothelial dysfunction in essential hypertension. (2006) (194)
- Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial. (2017) (193)
- Switching to Once-Daily Liraglutide From Twice-Daily Exenatide Further Improves Glycemic Control in Patients With Type 2 Diabetes Using Oral Agents (2010) (178)
- Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance. (2005) (170)
- Pathophysiology of insulin resistance. (2006) (164)
- Angiotensin II Impairs the Insulin Signaling Pathway Promoting Production of Nitric Oxide by Inducing Phosphorylation of Insulin Receptor Substrate-1 on Ser312 and Ser616 in Human Umbilical Vein Endothelial Cells (2004) (164)
- Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha. (2005) (160)
- Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study (2008) (155)
- The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. (1999) (154)
- Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential (2000) (154)
- The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes. (2006) (151)
- A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects. (2003) (150)
- Insulin Secretion in Metabolically Obese, but Normal Weight, and in Metabolically Healthy but Obese Individuals (2008) (148)
- Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis. (2009) (146)
- Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells. (1994) (137)
- A Phase 2, Randomized, Dose-Finding Study of the Novel Once-Weekly Human GLP-1 Analog, Semaglutide, Compared With Placebo and Open-Label Liraglutide in Patients With Type 2 Diabetes (2015) (136)
- Weight loss in combination with physical activity improves endothelial dysfunction in human obesity. (2003) (129)
- Safety issues with glucagon‐like peptide‐1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials (2017) (128)
- Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient (2002) (126)
- Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism. (2002) (126)
- The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes. (2004) (125)
- High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects (2014) (119)
- The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients—the EUGENE2 study (2008) (119)
- Uric Acid Is Associated With Inflammatory Biomarkers and Induces Inflammation Via Activating the NF-&kgr;B Signaling Pathway in HepG2 Cells (2017) (116)
- G972R IRS-1 Variant Impairs Insulin Regulation of Endothelial Nitric Oxide Synthase in Cultured Human Endothelial Cells (2004) (115)
- Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus. (1994) (113)
- Pulse pressure and endothelial dysfunction in never-treated hypertensive patients. (2003) (111)
- Association between a genetic variant related to glutamic acid metabolism and coronary heart disease in individuals with type 2 diabetes. (2013) (108)
- The functional Q84R polymorphism of mammalian Tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy. (2005) (108)
- A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus. (2009) (108)
- C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport (2007) (108)
- Effect of anti TNFalpha therapy on arterial diameter and wall shear stress and HDL cholesterol. (2004) (107)
- Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity (2020) (107)
- Endothelial Dysfunction and Subsequent Decline in Glomerular Filtration Rate in Hypertensive Patients (2010) (107)
- Heterogeneous Effect of Peroxisome Proliferator‐activated Receptor γ2 Ala12 Variant on Type 2 Diabetes Risk (2007) (107)
- Interleukin-6 Impairs the Insulin Signaling Pathway, Promoting Production of Nitric Oxide in Human Umbilical Vein Endothelial Cells (2007) (103)
- Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues (1997) (99)
- The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. (2000) (98)
- The common Arg972 polymorphism in insulin receptor substrate‐1 causes apoptosis of human pancreatic islets (2001) (95)
- One-Hour Postload Hyperglycemia Is a Stronger Predictor of Type 2 Diabetes Than Impaired Fasting Glucose. (2015) (93)
- C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance. (2005) (93)
- Molecular mechanism of insulin resistance in type 2 diabetes mellitus: role of the insulin receptor variant forms (2001) (92)
- Variants of the Interleukin-10 Promoter Gene Are Associated With Obesity and Insulin Resistance but Not Type 2 Diabetes in Caucasian Italian Subjects (2006) (92)
- Increased O‐glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic β‐cells (2004) (91)
- Altered Insulin Receptor Signalling and β-Cell Cycle Dynamics in Type 2 Diabetes Mellitus (2011) (88)
- Endothelial dysfunction, ADMA and insulin resistance in essential hypertension. (2010) (85)
- Review of Methods for Detecting Glycemic Disorders. (2020) (85)
- One-Hour Postload Plasma Glucose Levels and Left Ventricular Mass in Hypertensive Patients (2011) (84)
- Endothelial Dysfunction and C-Reactive Protein Are Risk Factors for Diabetes in Essential Hypertension (2008) (84)
- Nonalcoholic fatty liver disease is associated with low circulating levels of insulin-like growth factor-I. (2011) (83)
- The mammalian tribbles homolog TRIB3, glucose homeostasis, and cardiovascular diseases. (2012) (79)
- Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance. (2008) (77)
- One-hour postload plasma glucose levels are associated with kidney dysfunction. (2010) (77)
- Efficacy and safety of dapagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in diabetes mellitus (2015) (76)
- Obese Patients With a Binge Eating Disorder Have an Unfavorable Metabolic and Inflammatory Profile (2015) (76)
- Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release (2014) (75)
- Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects. (1996) (75)
- The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes. (2004) (74)
- Cardiometabolic Risk Profiles and Carotid Atherosclerosis in Individuals With Prediabetes Identified by Fasting Glucose, Postchallenge Glucose, and Hemoglobin A1c Criteria (2012) (73)
- Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells. (2004) (72)
- Insulin Sensitivity, β-Cell Function, and Incretin Effect in Individuals With Elevated 1-Hour Postload Plasma Glucose Levels (2012) (70)
- Liraglutide prevents cognitive decline in a rat model of streptozotocin-induced diabetes independently from its peripheral metabolic effects (2017) (69)
- Chronic hyperglycemia impairs insulin secretion by affecting insulin receptor expression, splicing, and signaling in RIN β‐cell line and human islets of Langerhans (2003) (69)
- An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics (2010) (68)
- Relation between serum uric acid and carotid intima-media thickness in healthy postmenopausal women (2007) (67)
- Relation of low bone mineral density and carotid atherosclerosis in postmenopausal women. (2004) (66)
- Endogenous testosterone and endothelial function in postmenopausal women (2007) (66)
- The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients. (2003) (65)
- A Candidate Type 2 Diabetes Polymorphism Near the HHEX Locus Affects Acute Glucose-Stimulated Insulin Release in European Populations (2008) (64)
- Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients (1997) (64)
- Variant near ADAMTS9 Known to Associate with Type 2 Diabetes Is Related to Insulin Resistance in Offspring of Type 2 Diabetes Patients—EUGENE2 Study (2009) (63)
- Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity. (1998) (62)
- Components of the Metabolic Syndrome and Carotid Atherosclerosis: Role of Elevated Blood Pressure (2005) (62)
- Association between One-Hour Post-Load Plasma Glucose Levels and Vascular Stiffness in Essential Hypertension (2012) (62)
- Role of C Reactive Protein (CRP) in Leptin Resistance (2014) (61)
- The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes. (2009) (61)
- Leptin-stimulated endothelial nitric-oxide synthase via an adenosine 5'-monophosphate-activated protein kinase/Akt signaling pathway is attenuated by interaction with C-reactive protein. (2009) (60)
- Insulin-like growth factor-I, inflammatory proteins, and fibrosis in subjects with nonalcoholic fatty liver disease. (2013) (60)
- Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance (2011) (59)
- Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects. (2009) (59)
- Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/L). (2018) (58)
- Relationships of surrogate indexes of insulin resistance with insulin sensitivity assessed by euglycemic hyperinsulinemic clamp and subclinical vascular damage (2019) (58)
- Expression of Insulin/IGF-I Hybrid Receptors Is Increased in Skeletal Muscle of Patients With Chronic Primary Hyperinsulinemia (1998) (57)
- Reciprocal Association of Plasma IGF-1 and Interleukin-6 Levels With Cardiometabolic Risk Factors in Nondiabetic Subjects (2008) (57)
- Effects of Weight Loss in Metabolically Healthy Obese Subjects after Laparoscopic Adjustable Gastric Banding and Hypocaloric Diet (2011) (55)
- TRIB3 R84 Variant Is Associated With Impaired Insulin-Mediated Nitric Oxide Production in Human Endothelial Cells (2008) (54)
- Impact of common polymorphisms in candidate genes for insulin resistance and obesity on weight loss of morbidly obese subjects after laparoscopic adjustable gastric banding and hypocaloric diet. (2005) (53)
- Molecular and Functional Characterization of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP-38)/Vasoactive Intestinal Polypeptide Receptors in Pancreatic β-Cells and Effects of PACAP-38 on Components of the Insulin Secretory System1. (1999) (52)
- Liraglutide improves cardiac function in patients with type 2 diabetes and chronic heart failure (2017) (52)
- Pharmacogenetics of type 2 diabetes mellitus, the route toward tailored medicine (2019) (52)
- Altered expression of the two naturally occurring human insulin receptor variants in isolated adipocytes of non-insulin-dependent diabetes mellitus patients. (1991) (52)
- Microvascular effects of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized controlled trials (2017) (51)
- Altered pattern of insulin receptor isotypes in skeletal muscle membranes of Type 2 (non-insulin-dependent) diabetic subjects (1993) (48)
- Continued efforts to translate diabetes cardiovascular outcome trials into clinical practice (2016) (48)
- Association between Noninvasive Fibrosis Markers and Chronic Kidney Disease among Adults with Nonalcoholic Fatty Liver Disease (2014) (48)
- The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes (2006) (48)
- Plasma Interleukin-6 Levels Are Independently Associated With Insulin Secretion in a Cohort of Italian-Caucasian Nondiabetic Subjects (2006) (47)
- Individualized Therapy for Type 2 Diabetes (2012) (46)
- Differences in insulin clearance between metabolically healthy and unhealthy obese subjects (2014) (46)
- Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus. (1997) (46)
- Efficacy of antihyperglycemic therapies and the influence of baseline hemoglobin A(1C): a meta-analysis of the liraglutide development program. (2011) (45)
- One-Hour Postload Plasma Glucose Levels and Diastolic Function in Hypertensive Patients (2011) (45)
- Glucagon-like peptide-1 receptor agonists and atrial fibrillation: a systematic review and meta-analysis of randomised controlled trials (2017) (44)
- Plasma interleukin‐6 levels are increased in subjects with impaired glucose tolerance but not in those with impaired fasting glucose in a cohort of Italian Caucasians (2007) (43)
- Low-plasma insulin-like growth factor-I levels are associated with impaired endothelium-dependent vasodilatation in a cohort of untreated, hypertensive Caucasian subjects. (2008) (43)
- The UCP2 ‐866 G>A promoter region polymorphism is associated with nonalcoholic steatohepatitis. (2015) (43)
- The use of real time continuous glucose monitoring or flash glucose monitoring in the management of diabetes: A consensus view of Italian diabetes experts using the Delphi method. (2019) (43)
- Apoptosis in the beta cells: cause or consequence of insulin secretion defect in diabetes? (2002) (42)
- The Gly972-->Arg IRS-1 variant is associated with type 1 diabetes in continental Italy. (2003) (42)
- Modulation of insulin secretion by diazepam binding inhibitor and its processing products (1991) (42)
- The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism (2016) (41)
- Association between hemoglobin glycation index with insulin resistance and carotid atherosclerosis in non-diabetic individuals (2017) (41)
- Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients. (2007) (41)
- Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells (1996) (41)
- Direct modulation of insulin receptor protein tyrosine kinase by vanadate and anti-insulin receptor monoclonal antibodies. (1988) (41)
- Impaired endothelial function in never-treated hypertensive subjects carrying the Arg972 polymorphism in the insulin receptor substrate-1 gene. (2004) (40)
- Ten years of experience with DPP-4 inhibitors for the treatment of type 2 diabetes mellitus (2019) (39)
- The place of gliclazide MR in the evolving type 2 diabetes landscape: A comparison with other sulfonylureas and newer oral antihyperglycemic agents. (2018) (39)
- Elevated 1 h postload plasma glucose levels identify adults with normal glucose tolerance but increased risk of non-alcoholic fatty liver disease (2014) (39)
- Durability of insulin degludec plus liraglutide versus insulin glargine U100 as initial injectable therapy in type 2 diabetes (DUAL VIII): a multicentre, open-label, phase 3b, randomised controlled trial. (2019) (38)
- Association between Noninvasive Fibrosis Markers and Cardio-Vascular Organ Damage among Adults with Hepatic Steatosis (2014) (38)
- Serum Uric Acid and 1-h Postload Glucose in Essential Hypertension (2011) (38)
- Interaction between uric acid and endothelial dysfunction predicts new onset of diabetes in hypertensive patients. (2013) (38)
- Molecular and cellular characterization of the GABAA receptor in the rat pancreas (1994) (37)
- Major cardiovascular events, heart failure, and atrial fibrillation in patients treated with glucagon-like peptide-1 receptor agonists: An updated meta-analysis of randomized controlled trials. (2020) (37)
- Mechanisms linking empagliflozin to cardiovascular and renal protection. (2017) (36)
- Interaction between vascular dysfunction and cardiac mass increases the risk of cardiovascular outcomes in essential hypertension. (2005) (36)
- Effects of glucagon-like peptide-1 receptor agonists on mortality and cardiovascular events: A comprehensive meta-analysis of randomized controlled trials. (2017) (35)
- Evidence for glucose/hexosamine in vivo regulation of insulin/IGF-I hybrid receptor assembly. (1999) (35)
- One-Hour Postload Hyperglycemia: Implications for Prediction and Prevention of Type 2 Diabetes (2018) (35)
- Effects of growth hormone and insulin-like growth factor-1 on cardiac hypertrophy of hypertensive patients (2007) (34)
- A Fasting Insulin–Raising Allele at IGF1 Locus Is Associated with Circulating Levels of IGF-1 and Insulin Sensitivity (2013) (34)
- One-hour post-load plasma glucose levels are associated with elevated liver enzymes. (2011) (33)
- Uric Acid Impairs Insulin Signaling by Promoting Enpp1 Binding to Insulin Receptor in Human Umbilical Vein Endothelial Cells (2018) (33)
- One-hour post-load hyperglycemia combined with HbA1c identifies pre-diabetic individuals with a higher cardio-metabolic risk burden. (2016) (33)
- Effect of insulin on hydrogen peroxide production by human polymorphonuclear leukocytes. Studies with monoclonal anti-insulin receptor antibodies, and an agonist and an inhibitor of protein kinase C. (1995) (33)
- The type 2 diabetes and insulin-resistance locus near IRS1 is a determinant of HDL cholesterol and triglycerides levels among diabetic subjects. (2011) (32)
- Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs. (2013) (32)
- Usefulness of hemoglobin A1c as a criterion to define the metabolic syndrome in a cohort of italian nondiabetic white subjects. (2011) (31)
- IGF-1 levels link estimated glomerular filtration rate to insulin resistance in obesity: a study in obese, but metabolically healthy, subjects and obese, insulin-resistant subjects. (2011) (31)
- Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia (2017) (31)
- Molecular and functional characterization of pituitary adenylate cyclase-activating polypeptide (PACAP-38)/vasoactive intestinal polypeptide receptors in pancreatic beta-cells and effects of PACAP-38 on components of the insulin secretory system. (1999) (31)
- Oxidative stress impairs endothelial function in nondipper hypertensive patients. (2012) (31)
- IL-18 gene polymorphism and metabolic syndrome. (2009) (30)
- IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of ‘low-frequency–low-risk’ variants (2009) (30)
- Metabolic and cardiovascular risk factors in subjects with impaired fasting glucose: the 100 versus 110 mg/dL threshold (2007) (30)
- Serum Alkaline Phosphatase Negatively Affects Endothelium-Dependent Vasodilation in Naïve Hypertensive Patients (2015) (30)
- Elevated 1-h post-load plasma glucose levels in subjects with normal glucose tolerance are associated with unfavorable inflammatory profile (2014) (30)
- Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B (2011) (30)
- Association of hepatic insulin resistance indexes to nonalcoholic fatty liver disease and related biomarkers. (2013) (30)
- Use and effectiveness of dapagliflozin in routine clinical practice: An Italian multicentre retrospective study (2018) (30)
- The TRIB3 R84 variant is associated with increased carotid intima-media thickness in vivo and with enhanced MAPK signalling in human endothelial cells. (2011) (29)
- Endothelial dysfunction and non-alcoholic liver steatosis in hypertensive patients. (2011) (29)
- Clinical factors associated with death in 3044 COVID-19 patients managed in internal medicine wards in Italy: results from the SIMI-COVID-19 study of the Italian Society of Internal Medicine (SIMI) (2021) (29)
- PCSK9 inhibitor therapy: A systematic review and meta‐analysis of metabolic and cardiovascular outcomes in patients with diabetes (2019) (29)
- Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion. (2008) (29)
- Evidence That Two Naturally Occurring Human Insulin Receptor α-Subunit Variants Are Immunologically Distinct (1992) (28)
- Association of LDL cholesterol with carotid atherosclerosis in menopausal women affected by the metabolic syndrome. (2005) (28)
- Polymorphisms of the insulin receptor substrate-2 in patients with type 2 diabetes. (2003) (28)
- Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension. (2008) (28)
- Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study and crowdsourcing opportunity. (2017) (27)
- Asymmetric Dimethylarginine Plasma Levels and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients (2012) (27)
- Insulin receptor substrate polymorphisms and type 2 diabetes mellitus. (2000) (27)
- Management of diabetes in older adults. (2017) (27)
- PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes. (2008) (27)
- Positive association between plasma IGF1 and high-density lipoprotein cholesterol levels in adult nondiabetic subjects. (2010) (27)
- Impact of Mediterranean Diet on Disease Activity and Gut Microbiota Composition of Rheumatoid Arthritis Patients (2020) (26)
- Association between hemoglobin glycation index and hepatic steatosis in non-diabetic individuals. (2017) (26)
- CHADS2 and CHA2DS2-VASc scores are independently associated with incident atrial fibrillation: the Catanzaro Atrial Fibrillation Project (2015) (26)
- Risk reclassification ability of uric acid for cardiovascular outcomes in essential hypertension. (2017) (26)
- Decreased Insulin Clearance in Individuals with Elevated 1-h Post-Load Plasma Glucose Levels (2013) (26)
- Comparison of A1C, fasting and 2-h post-load plasma glucose criteria to diagnose diabetes in Italian Caucasians. (2012) (26)
- Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals (2017) (25)
- Low insulin-like growth factor-1 levels are associated with anaemia in adult non-diabetic subjects (2010) (25)
- Tissue-specific expression of two alternatively spliced isoforms of the human insulin receptor protein (1994) (25)
- Higher serum levels of uric acid are associated with a reduced insulin clearance in non-diabetic individuals (2018) (24)
- Carotid atherosclerosis associated to metabolic syndrome but not BMI in healthy menopausal women. (2007) (24)
- Metabolic and Cognitive Effects of Ranolazine in Type 2 Diabetes Mellitus: Data from an in vivo Model (2020) (24)
- Uric acid is an independent predictor of cardiovascular events in post-menopausal women. (2015) (24)
- Renal disease and left atrial remodeling predict atrial fibrillation in patients with cardiovascular risk factors. (2014) (24)
- Role of endogenous androgens on carotid atherosclerosis in non-obese postmenopausal women. (2007) (24)
- Additive Effect of Non-Alcoholic Fatty Liver Disease on Metabolic Syndrome-Related Endothelial Dysfunction in Hypertensive Patients (2016) (24)
- Coinfection of Tuberculosis Pneumonia and COVID-19 in a Patient Vaccinated with Bacille Calmette-Guérin (BCG): Case Report (2020) (24)
- Ketogenic Diet-Induced Weight Loss is Associated with an Increase in Vitamin D Levels in Obese Adults (2019) (24)
- SRT1720 counteracts glucosamine-induced endoplasmic reticulum stress and endothelial dysfunction. (2015) (23)
- A polymorphism at IGF1 locus is associated with carotid intima media thickness and endothelium-dependent vasodilatation. (2014) (23)
- One‐hour post‐load hyperglycemia combined with HbA1c identifies individuals with higher risk of cardiovascular diseases: Cross‐sectional data from the CATAMERI study (2018) (23)
- One-Hour Postload Hyperglycemia Confers Higher Risk of Hepatic Steatosis to HbA1c-Defined Prediabetic Subjects. (2016) (23)
- Liraglutide achieves A1C targets more often than sitagliptin or exenatide when added to metformin in patients with type 2 diabetes and a baseline A1C <8.0%. (2013) (22)
- Large brachial and common carotid artery diameter in postmenopausal women with carotid atherosclerosis. (2008) (22)
- Predictors of response to glucagon-like peptide-1 receptor agonists: a meta-analysis and systematic review of randomized controlled trials (2017) (22)
- Elevated Concentrations of Liver Enzymes and Ferritin Identify a New Phenotype of Insulin Resistance: Effect of Weight Loss After Gastric Banding (2009) (22)
- An extracellular domain of the insulin receptor beta-subunit with regulatory function on protein-tyrosine kinase. (1989) (22)
- Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance (2020) (22)
- The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells. (2011) (21)
- Kinetics of the B- and T-Cell Immune Responses After 6 Months From SARS-CoV-2 mRNA Vaccination in Patients With Rheumatoid Arthritis (2022) (21)
- A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity (2012) (21)
- Nutrition, Metabolism & Cardiovascular Diseases (2014) (21)
- Recurrent COVID‐19 pneumonia in the course of chemotherapy: Consequence of a weakened immune system? (2020) (20)
- Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertension (1996) (20)
- Androgens increase insulin receptor mRNA levels, insulin binding, and insulin responsiveness in HEp-2 larynx carcinoma cells (1992) (20)
- Elevated 1-h post-load plasma glucose levels in subjects with normal glucose tolerance are associated with a pro-atherogenic lipid profile. (2017) (20)
- New insights into body composition assessment in obese women. (1999) (19)
- Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor (1995) (19)
- Reduction in Global Myocardial Glucose Metabolism in Subjects With 1-Hour Postload Hyperglycemia and Impaired Glucose Tolerance (2020) (19)
- Low circulating insulin-like growth factor-1 levels are associated with high serum uric acid in nondiabetic adult subjects. (2014) (19)
- Insulin-resistance HCV infection-related affects vascular stiffness in normotensives. (2015) (19)
- Variance of the SGK1 Gene Is Associated with Insulin Secretion in Different European Populations: Results from the TUEF, EUGENE2, and METSIM Studies (2008) (18)
- The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms. (2001) (18)
- Chronic HCV infection increases cardiac left ventricular mass index in normotensive patients. (2014) (18)
- Quantitative analysis of pancreatic glucokinase gene expression in cultured β cells by competitive polymerase chain reaction (1996) (18)
- Insulin-like growth factor-1 and glomerular filtration rate in hypertensive patients (2009) (18)
- G 972 R IRS-1 Variant Impairs Insulin Regulation of Endothelial Nitric Oxide Synthase in Cultured Human Endothelial Cells (2004) (17)
- TRIB3 R84 variant affects glucose homeostasis by altering the interplay between insulin sensitivity and secretion (2010) (17)
- Metabolic Syndrome (2015) (16)
- Elevated 1-h post-challenge plasma glucose levels in subjects with normal glucose tolerance or impaired glucose tolerance are associated with whole blood viscosity (2017) (16)
- Hypoglycemia Assessed by Continuous Glucose Monitoring Is Associated with Preclinical Atherosclerosis in Individuals with Impaired Glucose Tolerance (2011) (16)
- Renal function predicts cardiovascular outcomes in southern Italian postmenopausal women (2009) (16)
- Pioglitazone corrects dysregulation of skeletal muscle mitochondrial proteins involved in ATP synthesis in type 2 diabetes. (2020) (16)
- Plasma complement C3 levels are associated with insulin secretion independently of adiposity measures in non-diabetic individuals. (2015) (16)
- in IRS-1 impairs insulin secretion in pancreatic β cells (1999) (16)
- Psychological Distress in Patients with Autoimmune Arthritis during the COVID-19 Induced Lockdown in Italy (2020) (16)
- Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation. (2007) (15)
- Beta-endorphin receptors on cultured and freshly isolated lymphocytes from normal subjects. (1989) (15)
- Relation of fasting insulin related to insertion/deletion polymorphism of angiotensin-converting enzyme-gene and cardiac mass in never-treated patients with systemic hypertension. (2003) (15)
- Joint effect of insulin signaling genes on insulin secretion and glucose homeostasis. (2013) (15)
- Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis (2021) (15)
- Insulin receptor variant forms and type 2 diabetes mellitus. (2000) (15)
- Vitamin D and 1-hour post-load plasma glucose in hypertensive patients (2014) (15)
- Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes. (2007) (14)
- Searching for type 2 diabetes genes: prospects in pharmacotherapy (2002) (14)
- Immunity, Inflammation and Heart Failure: Their Role on Cardiac Function and Iron Status (2019) (14)
- Unfavorable inflammatory profile in adults at risk of type 2 diabetes identified by hemoglobin A1c levels according to the American Diabetes Association criteria (2015) (14)
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- High prevalence of elevated liver enzymes and glucose intolerance in morbid obese patients are reduced after laparoscopic adjustable gastric banding (LAGB) (2007) (0)
- The polymorphism rs35767 at IGF1 locus is associated with serum urate levels (2018) (0)
- Current diagnostic criteria identify risk for type 2 diabetes too late. (2023) (0)
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What Schools Are Affiliated With Giorgio Sesti?
Giorgio Sesti is affiliated with the following schools:
