Giorgio Zauli
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Computer Science
Giorgio Zauli's Degrees
- PhD Computer Science University of Milan
- Masters Computer Science University of Milan
- Bachelors Computer Science University of Milan
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(Suggest an Edit or Addition)Giorgio Zauli's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cyclooxygenase-2 expression is induced during human megakaryopoiesis and characterizes newly formed platelets (2002) (320)
- TRAIL Promotes the Survival and Proliferation of Primary Human Vascular Endothelial Cells by Activating the Akt and ERK Pathways (2003) (304)
- Cytokine Levels in the Serum of Healthy Subjects (2013) (297)
- Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging (2018) (283)
- COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males? (2020) (263)
- microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. (2010) (224)
- tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced hematopoietic suppression. (1992) (195)
- Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity. (2004) (189)
- MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer (2017) (185)
- TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis. (2000) (185)
- HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions. (1998) (177)
- Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL). (2006) (168)
- Recent advances in the therapeutic perspectives of Nutlin-3. (2011) (154)
- Systemic Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Delivery Shows Antiatherosclerotic Activity in Apolipoprotein E–Null Diabetic Mice (2006) (148)
- An increased osteoprotegerin serum release characterizes the early onset of diabetes mellitus and may contribute to endothelial cell dysfunction. (2006) (144)
- Human Bone Marrow Mesenchymal Stem Cells Display Anti-Cancer Activity in SCID Mice Bearing Disseminated Non-Hodgkin's Lymphoma Xenografts (2010) (142)
- The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology. (2006) (138)
- Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells. (1999) (138)
- Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis. (1993) (138)
- NF-κB pathways in hematological malignancies (2014) (136)
- Optimal detection of apoptosis by flow cytometry depends on cell morphology. (1993) (135)
- TRAIL promotes the survival, migration and proliferation of vascular smooth muscle cells (2004) (135)
- Osteoprotegerin increases leukocyte adhesion to endothelial cells both in vitro and in vivo. (2007) (134)
- Emerging non‐apoptotic functions of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL)/Apo2L (2004) (132)
- TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. (2004) (128)
- Effect of antibody to HIV-1 Tat protein on viral replication in vitro and progression of HIV-1 disease in vivo. (1995) (124)
- The human immunodeficiency virus type-1 Tat protein upregulates Bcl-2 gene expression in Jurkat T-cell lines and primary peripheral blood mononuclear cells. (1995) (124)
- Antiangiogenic Activity of the MDM2 Antagonist Nutlin-3 (2007) (122)
- Tumor Necrosis Factor‐Related Apoptosis‐Inducing Ligand (TRAIL) Sequentially Upregulates Nitric Oxide and Prostanoid Production in Primary Human Endothelial Cells (2003) (121)
- Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD4+ T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD95/CD95 Ligand Pathway (1999) (116)
- TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. (2005) (108)
- TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF. (2004) (102)
- Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)--mediated cytotoxicity by selective up-regulation of TRAIL-R1. (2001) (101)
- Impaired in vitro growth of purified (CD34+) hematopoietic progenitors in human immunodeficiency virus-1 seropositive thrombocytopenic individuals. (1992) (101)
- Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes. (2005) (95)
- Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells. (2002) (94)
- The MDM2 inhibitor Nutlins as an innovative therapeutic tool for the treatment of haematological malignancies. (2008) (93)
- A subset of human CD34+ hematopoietic progenitors express low levels of CD4, the high-affinity receptor for human immunodeficiency virus-type 1. (1994) (93)
- Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults. (2011) (91)
- Tumor necrosis factor-related apoptosis-inducing ligand induces monocytic maturation of leukemic and normal myeloid precursors through a caspase-dependent pathway. (2002) (91)
- In vitro growth and regulation of bone marrow enriched CD34+ hematopoietic progenitors in Diamond-Blackfan anemia. (1991) (91)
- Role of the extracellular domain of human herpesvirus 7 glycoprotein B in virus binding to cell surface heparan sulfate proteoglycans (1997) (89)
- Extracellular HIV‐1 Tat protein activates phosphatidylinositol 3‐ and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells (1997) (87)
- Pleiotropic effects of immobilized versus soluble recombinant HIV-1 Tat protein on CD3-mediated activation, induction of apoptosis, and HIV-1 long terminal repeat transactivation in purified CD4+ T lymphocytes. (1996) (85)
- Potential Prognostic Significance of Decreased Serum Levels of TRAIL after Acute Myocardial Infarction (2009) (85)
- Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism. (2009) (83)
- HIV-1 Tat-mediated Inhibition of the Tyrosine Hydroxylase Gene Expression in Dopaminergic Neuronal Cells* (2000) (82)
- Extracellular Human Immunodeficiency Virus Type-1 Tat Protein Activates Phosphatidylinositol 3-Kinase in PC12 Neuronal Cells* (1996) (80)
- In vitro senescence and apoptotic cell death of human megakaryocytes. (1997) (80)
- Tumour necrosis factor‐related apoptosis‐inducing ligand sequentially activates pro‐survival and pro‐apoptotic pathways in SK‐N‐MC neuronal cells (2003) (80)
- Tumor necrosis factor-related apoptosis-inducing ligand and the regulation of hematopoiesis (2008) (80)
- In vivo and in vitro inhibitory effect of α‐interferon on megakaryocyte colony growth in essential thrombocythaemia (1989) (78)
- In Vitro Senescence and Apoptotic Cell Death of Human Megakaryocytes (1997) (78)
- Evidence for a human immunodeficiency virus type 1-mediated suppression of uninfected hematopoietic (CD34+) cells in AIDS patients. (1992) (77)
- Role of full-length osteoprotegerin in tumor cell biology (2009) (76)
- Early loss of circulating hemopoietic progenitors in HIV-1-infected subjects. (1990) (75)
- miR-34a Induces the Downregulation of Both E2F1 and B-Myb Oncogenes in Leukemic Cells (2011) (73)
- Inhibition of purified CD34+ hematopoietic progenitor cells by human immunodeficiency virus 1 or gp120 mediated by endogenous transforming growth factor beta 1 (1996) (73)
- Recombinant human immunodeficiency virus type‐1 (HIV‐1) Tat protein sequentially up‐regulates IL‐6 and TFG‐β1 mRNA expression and protein synthesis in peripheral blood monocytes (1994) (72)
- Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells. (2007) (70)
- Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies. (2001) (70)
- TRAIL inhibits osteoclastic differentiation by counteracting RANKL‐dependent p27Kip1 accumulation in pre‐osteoclast precursors (2008) (69)
- An imbalanced OPG/TRAIL ratio is associated to severe acute myocardial infarction. (2010) (66)
- Uninfected haematopoietic progenitor (CD34+) cells purified from the bone marrow of AIDS patients are committed to apoptotic cell death in culture (1993) (66)
- PI‐3K/Akt and NF‐κB/IκBα pathways are activated in Jurkat T cells in response to TRAIL treatment (2005) (66)
- Impact of physical exercise in cancer survivors during and after antineoplastic treatments (2015) (65)
- HIV type 1 extracellular Tat protein stimulates growth and protects cells of BK virus/tat transgenic mice from apoptosis. (1995) (64)
- Thrombopoietin Enhances the αIIbβ3-Dependent Adhesion of Megakaryocytic Cells to Fibrinogen or Fibronectin Through PI 3 Kinase (1997) (63)
- Treatment With Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alleviates the Severity of Streptozotocin-Induced Diabetes (2010) (62)
- Nuclear translocation of protein kinase C‐α and ‐ζ isoforms in HL‐60 cells induced to differentiate along the granulocytic lineage by all‐trans retinoic acid (1996) (62)
- Extracellular HIV-1 Tat protein induces the rapid Ser133 phosphorylation and activation of CREB transcription factor in both Jurkat lymphoblastoid T cells and primary peripheral blood mononuclear cells. (1998) (62)
- Human immunodeficiency virus type 1 envelope glycoprotein gp120-mediated killing of human haematopoietic progenitors (CD34+ cells). (1992) (61)
- An autocrine loop of HIV type-1 Tat protein responsible for the improved survival/proliferation capacity of permanently Tat-transfected cells and required for optimal HIV-1 LTR transactivating activity. (1995) (61)
- Tumor Necrosis Factor‐Related Apoptosis‐Inducing Ligand Promotes Migration of Human Bone Marrow Multipotent Stromal Cells (2008) (61)
- Evidence for a proangiogenic activity of TNF-related apoptosis-inducing ligand. (2004) (60)
- Tat‐expressing Jurkat cells show an increased resistance to different apoptotic stimuli, including acute human immunodeficiency virus‐type 1 (HIV ‐1) infection (1995) (60)
- IMP dehydrogenase inhibitor, tiazofurin, induces apoptosis in K562 human erythroleukemia cells. (1997) (59)
- Changes of nuclear protein kinase C activity and isotype composition in PC12 cell proliferation and differentiation. (1996) (59)
- Ultrastructural characterization of maturation, platelet release, and senescence of human cultured megakaryocytes (2000) (55)
- Endothelial Cells Obtained from Patients Affected by Chronic Venous Disease Exhibit a Pro-Inflammatory Phenotype (2012) (54)
- In vivo effect of human granulocyte-macrophage colony-stimulating factor on megakaryocytopoiesis. (1991) (54)
- Impaired survival of bone marrow GPIIb/IIIa+ megakaryocytic cells as an additional pathogenetic mechanism of HIV‐1‐related thrombocytopenia (1996) (54)
- Cell-Based Therapies for Diabetic Complications (2011) (53)
- Osteoprotegerin promotes vascular fibrosis via a TGF-β1 autocrine loop. (2011) (53)
- The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts. (2007) (52)
- Involvement of the pathway phosphatidylinositol-3-kinase/AKT-1 in the establishment of the survival response to ionizing radiation. (2001) (52)
- Dasatinib Plus Nutlin-3 Shows Synergistic Antileukemic Activity in Both p53wild-type and p53mutated B Chronic Lymphocytic Leukemias by Inhibiting the Akt Pathway (2010) (52)
- Fine tuning of protein kinase C (PKC) isoforms in cancer: shortening the distance from the laboratory to the bedside. (2011) (52)
- Osteoprotegerin increases in metabolic syndrome and promotes adipose tissue proinflammatory changes (2014) (52)
- Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation (2014) (51)
- Effect of human immunodeficiency virus infection on haematopoiesis. (1995) (50)
- HIV‐1 Tat protein concomitantly down‐regulates apical caspase‐10 and up‐regulates c‐FLIP in lymphoid T cells: A potential molecular mechanism to escape TRAIL cytotoxicity (2005) (50)
- HIV‐1 Tat protein down‐regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3‐kinase/AKT/cyclic nucleoside phosphodiesterase pathway (2001) (49)
- Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway. (1999) (49)
- Potential pathogenetic implications of cyclooxygenase-2 overexpression in B chronic lymphoid leukemia cells. (2005) (49)
- TNF-related apoptosis-inducing ligand (TRAIL): a potential candidate for combined treatment of hematological malignancies. (2004) (48)
- Perspectives of protein kinase C (PKC) inhibitors as anti-cancer agents. (2009) (48)
- Influence of the human immunodeficiency virus type 1 Tat protein on the proliferation and differentiation of PC12 rat pheochromocytoma cells. (1993) (47)
- The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status (2012) (47)
- Stromal derived factor‐1α (SDF‐1α) induces CD4+ T cell apoptosis via the functional up‐regulation of the Fas (CD95)/Fas ligand (CD95L) pathway (2001) (47)
- Lineage-restricted expression of protein kinase C isoforms in hematopoiesis. (1999) (47)
- Extracellular HIV-1 Tat protein differentially activates the JNK and ERK/MAPK pathways in CD4 T cells. (1999) (47)
- Reduced responsiveness of bone marrow megakaryocyte progenitors to platelet‐derived transforming growth factor β1, produced in normal amount, in patients with essential thrombocythaemia (1993) (46)
- Proper design of silica nanoparticles combines high brightness, lack of cytotoxicity and efficient cell endocytosis. (2013) (45)
- In vitro exposure to human immunodeficiency virus type 1 induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line (1994) (45)
- In vitro exposure to human immunodeficiency virus type 1 induces apoptotic cell death of the factor-dependent TF-1 hematopoietic cell line. (1994) (45)
- Cardiovascular disease-related miRNAs expression: potential role as biomarkers and effects of training exercise (2018) (44)
- Human Herpesvirus 7 induces CD4(+) T-cell death by two distinct mechanisms: necrotic lysis in productively infected cells and apoptosis in uninfected or nonproductively infected cells. (1997) (44)
- Mouse peritoneal cells as a reservoir of late dendritic cell progenitors (1999) (44)
- Involvement of TRAIL/TRAIL‐receptors in human intestinal cell differentiation (2006) (43)
- Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases (2018) (42)
- Role of physical exercise in the regulation of epigenetic mechanisms in inflammation, cancer, neurodegenerative diseases, and aging process (2019) (42)
- Interleukin‐2 activates nuclear phospholipase‐Cβ by mitogen‐activated protein kinase‐dependent phosphorylation in human natural killer cells (2001) (42)
- Infection of CD34(+) hematopoietic progenitor cells by human herpesvirus 7 (HHV-7). (2000) (42)
- Applications of nanoparticles in cancer medicine and beyond: optical and multimodal in vivo imaging, tissue targeting and drug delivery (2015) (42)
- HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts (2018) (42)
- TNF-related apoptosis-inducing ligand significantly attenuates metabolic abnormalities in high-fat-fed mice reducing adiposity and systemic inflammation. (2012) (42)
- PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment. (2005) (41)
- Impaired telomerase activity in uninfected haematopoietic progenitors in HIV‐1‐infected patients (1998) (40)
- Influence of physical exercise on microRNAs in skeletal muscle regeneration, aging and diseases (2018) (39)
- Roles and clinical implications of microRNAs in acute lymphoblastic leukemia (2018) (39)
- The human immunodeficiency virus type-1 (HIV-1) Tat protein and Bcl-2 gene expression. (1996) (39)
- Targeting mTOR in Acute Lymphoblastic Leukemia (2019) (38)
- PMA‐induced megakaryocytic differentiation of HEL cells is accompanied by striking modifications of protein kinase C catalytic activity and isoform composition at the nuclear level (1996) (38)
- Antibody against human immunodeficiency virus type 1 (HIV-1) Tat protein may have influenced the progression of AIDS in HIV-1-infected hemophiliac patients (1996) (38)
- Actively targeted nanocarriers for drug delivery to cancer cells (2019) (37)
- C-Reactive Protein Downregulates TRAIL Expression in Human Peripheral Monocytes via an Egr-1–Dependent Pathway (2013) (37)
- Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway. (2001) (36)
- Osteoprotegerin induces morphological and functional alterations in mouse pancreatic islets (2011) (36)
- Extracellular HIV-1 Tat Protein Induces a Rapid and Selective Activation of Protein Kinase C (PKC)-α, -ϵ, and -ζ Isoforms in PC12 Cells (1998) (36)
- Clinical perspectives of TRAIL: insights into central nervous system disorders (2016) (36)
- TRAIL Modulates the Immune System and Protects against the Development of Diabetes (2015) (36)
- Upregulation of c-Fos in activated T lymphoid and monocytic cells by human immunodeficiency virus-1 Tat protein. (1997) (36)
- The induction of megakaryocyte differentiation is accompanied by selective Ser133 phosphorylation of the transcription factor CREB in both HEL cell line and primary CD34+ cells. (1998) (36)
- Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) regulates endothelial nitric oxide synthase (eNOS) activity and its localization within the human vein endothelial cells (HUVEC) in culture (2006) (35)
- HIV-1 Tat protects CD4+ Jurkat T lymphoblastoid cells from apoptosis mediated by TNF-related apoptosis-inducing ligand. (2001) (34)
- Progressive and persistent downregulation of surface CXCR4 in CD4(+) T cells infected with human herpesvirus 7. (1998) (34)
- Redox signaling and oxidative stress: Cross talk with TNF-related apoptosis inducing ligand activity. (2016) (34)
- State of art and recent developments of anti-cancer strategies based on TRAIL. (2012) (34)
- Role of CREB transcription factor in c‐fos activation in natural killer cells (2002) (34)
- Kinetics of in vitro natural killer activity against K562 cells as detected by flow cytometry. (1998) (34)
- Role of the RANKL/RANK system in the induction of interleukin‐8 (IL‐8) in B chronic lymphocytic leukemia (B‐CLL) cells (2006) (34)
- Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells. (2008) (34)
- Effect of different human immunodeficiency virus type‐1 (HIV‐1) isolates on long‐term bone marrow haemopoiesis (1993) (34)
- Metalloproteinase 2 cleaves in vitro recombinant TRAIL: potential implications for the decreased serum levels of TRAIL after acute myocardial infarction. (2010) (33)
- Engagement of CD28 Modulates CXC Chemokine Receptor 4 Surface Expression in Both Resting and CD3-Stimulated CD4+ T Cells1 (2000) (33)
- Accumulation of catalytically active PKC‐ζ into the nucleus of HL‐60 cell line plays a key role in the induction of granulocytic differentiation mediated by all‐trans retinoic acid (1998) (33)
- The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: implications in rheumatoid arthritis. (2008) (32)
- Functional expression of TRAIL and TRAIL‐R2 during human megakaryocytic development (2005) (31)
- Presence and Characteristics of Circulating Megakaryocyte Progenitor Cells in Human Fetal Blood (1993) (31)
- Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction (2014) (31)
- HIV‐1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3‐kinase in PC12 cells (1998) (31)
- The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells (2015) (30)
- Differential production of IFN-gamma, analyzed at the single-cell level, by specific subsets of human NK and T cells from healthy and HIV(+) subjects. (2000) (30)
- Human immunodeficiency virus type 1 (HIV-1) tat-protein stimulates the production of interleukin-6 (IL-6) by peripheral blood monocytes. (1993) (30)
- In vitro growth of human fetal CD34+ cells in the presence of various combinations of recombinant cytokines under serum‐free culture conditions (1994) (29)
- The Combination of N-Acetyl Cysteine, Alpha-Lipoic Acid, and Bromelain Shows High Anti-Inflammatory Properties in Novel In Vivo and In Vitro Models of Endometriosis (2015) (29)
- In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome (2013) (29)
- Comparison between different laboratory tests for the detection and prevention of heparin-induced thrombocytopenia. (2001) (29)
- Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4(+) T cells. (2001) (29)
- The Oncogene DEK Promotes Leukemic Cell Survival and Is Downregulated by both Nutlin-3 and Chlorambucil in B-Chronic Lymphocytic Leukemic Cells (2010) (29)
- Nanoparticles Engineered with Rituximab and Loaded with Nutlin-3 Show Promising Therapeutic Activity in B-Leukemic Xenografts (2013) (28)
- Aberrant expression of TRAIL in B chronic lymphocytic leukemia (B‐CLL) cells (2005) (28)
- Targeting the phosphatidylinositol 3‐kinase/Akt/mechanistic target of rapamycin signaling pathway in B‐lineage acute lymphoblastic leukemia: An update (2018) (28)
- Tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (TRAIL) and TNF‐α promote the NF‐κB‐dependent maturation of normal and leukemic myeloid cells (2003) (28)
- Prevalence of the primitive megakaryocyte progenitors (BFU-meg) in adult human peripheral blood. (1992) (28)
- Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication. (2000) (27)
- MDM4 (MDMX) is overexpressed in chronic lymphocytic leukaemia (CLL) and marks a subset of p53wild‐type CLL with a poor cytotoxic response to Nutlin‐3 (2010) (27)
- Human megakaryocyte biology and pathophysiology. (1995) (26)
- Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein. (1994) (26)
- Role of HIV infection in the hematologic manifestations of HIV seropositive subjects. (1993) (26)
- Thrombopoietin enhances the alpha IIb beta 3-dependent adhesion of megakaryocytic cells to fibrinogen or fibronectin through PI 3 kinase. (1997) (26)
- Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia (2015) (26)
- Inhibitory Effect of Natural Anti-Inflammatory Compounds on Cytokines Released by Chronic Venous Disease Patient-Derived Endothelial Cells (2013) (25)
- TRAIL reduces impaired glucose tolerance and NAFLD in the high-fat diet fed mouse. (2018) (25)
- Human herpesvirus 7 induces the down-regulation of CD4 antigen in lymphoid T cells without affecting p56lck levels. (1997) (25)
- Insulin down‐regulates TRAIL expression in vascular smooth muscle cells both in vivo and in vitro (2007) (25)
- Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases (2017) (25)
- HIV-1-related mechanisms of suppression of CD34+ hematopoietic progenitors. (1996) (24)
- Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3 (2014) (24)
- MDM2 Antagonist Nutlin‐3 Suppresses the Proliferation and Differentiation of Human Pre‐Osteoclasts Through a p53‐Dependent Pathway (2007) (24)
- In vivo and in vitro production of haemopoietic colony-stimulating activity by murine cell lines of different origin: a frequent finding. (1989) (24)
- Essential thrombocythemia: impaired regulation of megakaryocyte progenitors. (1991) (23)
- Human Herpesvirus 7 Infection Induces Profound Cell Cycle Perturbations Coupled to Disregulation of cdc2 and Cyclin B and Polyploidization of CD4+ T Cells (1998) (23)
- Physical training interventions for children and teenagers affected by acute lymphoblastic leukemia and related treatment impairments (2018) (23)
- Human herpesvirus type 7 in Hodgkin's disease (1998) (23)
- The MDM2 inhibitor Nutlin-3 modulates dendritic cell-induced T cell proliferation. (2012) (23)
- Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1 (2016) (23)
- Patients affected by metabolic syndrome show decreased levels of circulating platelet derived growth factor (PDGF)-BB. (2013) (23)
- The levels of circulating TRAIL at the onset of type 1 diabetes are markedly decreased in patients with ketoacidosis and with the highest insulin requirement (2014) (23)
- Soluble TRAIL is elevated in recurrent miscarriage and inhibits the in vitro adhesion and migration of HTR8 trophoblastic cells. (2012) (23)
- Selective up‐regulation of functional CXCR4 expression in erythroid cells by HIV‐1 Tat protein (2003) (22)
- TRAIL-based therapeutic approaches for the treatment of pediatric malignancies. (2013) (22)
- TNF-α modulates the migratory response of mesenchymal stem cells to TRAIL (2010) (22)
- Evidence for an HIV-1 mediated suppression of in vitro growth of enriched (CD34+) hematopoietic progenitors. (1991) (22)
- Endothelial PDGF-BB produced ex vivo correlates with relevant hemodynamic parameters in patients affected by chronic venous disease. (2013) (22)
- Differential effects of stromal derived factor‐1α (SDF‐1α) on early and late stages of human megakaryocytic development (2000) (21)
- TRAIL pathway components and their putative role in granulosa cell apoptosis in the human ovary. (2009) (21)
- Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model (2017) (21)
- Selective modulation of the cyclin B/CDK1 and cyclin D/CDK4 complexes during in vitro human megakaryocyte development (1999) (21)
- Increased serum levels of transforming growth factor β‐1 in patients affected by thrombotic thrombocytopenic purpura (TTP): its implications on bone marrow haematopoiesis (1993) (21)
- Multiple dye-doped NIR-emitting silica nanoparticles for both flow cytometry and in vivo imaging (2014) (21)
- Trail down‐regulates the release of osteoprotegerin (OPG) by primary stromal cells (2011) (21)
- Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia (2016) (20)
- Differentially expressed genes in HIV-1 tat-expressing CD4(+) T-cell line. (2002) (20)
- Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia (2016) (20)
- Lack of compensatory megakaryocytopoiesis in HIV-1-seropositive thrombocytopenic individuals compared with immune thrombocytopenic purpura patients. (1991) (20)
- Apoptosis induced by NK cells is modulated by the NK-active cytokines IL-2 and IL-12. (1998) (20)
- Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities (2016) (20)
- The inhibitory effect of serum from hairy‐cell leukaemia patients on normal progenitor cells may disappear following prolonged treatment with α‐interferon (1989) (20)
- Morphological features of osteoclasts derived from a co-culture system (2006) (19)
- Association of Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) with Central Adiposity and Low-Density Lipoprotein Cholesterol (2013) (19)
- Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells. (2003) (19)
- Human herpesvirus 7 infection induces profound cell cycle perturbations coupled to disregulation of cdc2 and cyclin B and polyploidization of CD4(+) T cells. (1998) (19)
- Stroma-derived factor 1α induces a selective inhibition of human erythroid development via the functional upregulation of Fas/CD95 ligand (2000) (19)
- The MDM2 inhibitor Nutlin-3 attenuates streptozotocin-induced diabetes mellitus and increases serum level of IL-12p40 (2013) (19)
- Design, Synthesis, and Biological Characterization of Novel Mitochondria Targeted Dichloroacetate-Loaded Compounds with Antileukemic Activity. (2016) (19)
- All-trans retinoic acid and induction of apoptosis in acute promyelocytic leukemia cells. (1994) (19)
- Selective up‐regulation of phospholipase C‐β2 during granulocytic differentiation of normal and leukemic hematopoietic progenitors (2002) (19)
- SARS-CoV-2 nucleocapsid protein and ultrastructural modifications in small bowel of a 4-week-negative COVID-19 patient (2021) (18)
- TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets? (2019) (18)
- GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients (2013) (18)
- Morphological features of apoptosis in hematopoietic cells belonging to the T-lymphoid and myeloid lineages. (2000) (18)
- Human papillomavirus infection is associated with decreased levels of GM-CSF in cervico-vaginal fluid of infected women. (2013) (18)
- In situ polymerase chain reaction technique revealed by flow cytometry as a tool for gene detection. (1995) (18)
- Nutlin-3 Downregulates the Expression of the Oncogene TCL1 in Primary B Chronic Lymphocytic Leukemic Cells (2011) (18)
- Differential effects of stromal derived factor-1 alpha (SDF-1 alpha) on early and late stages of human megakaryocytic development. (2000) (18)
- TNF‐related apoptosis‐inducing ligand (TRAIL) up‐regulates cyclooxygenase (COX)‐1 activity and PGE2 production in cells of the myeloid lineage (2002) (17)
- Human Colostrum and Breast Milk Contain High Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL) (2013) (17)
- Nuclear translocation of protein kinase C-alpha and -zeta isoforms in HL-60 cells induced to differentiate along the granulocytic lineage by all-trans retinoic acid. (1996) (17)
- Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application (2013) (17)
- Impaired GM-CSF production by cultured light density mononuclear cells and T lymphocytes correlates with the number of circulating CFU-gm in HIV-1 seropositive subjects. (1991) (17)
- TRAIL promotes a pro-survival signal in erythropoietin-deprived human erythroblasts through the activation of an NF-kB/IkBalpha pathway. (2011) (16)
- Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells. (1998) (16)
- The anti-leukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53-independent ILF3/p21 pathway (2014) (16)
- Selective modulation of specific protein kinase C (PKC) isoforms in primary human megakaryocytic vs. erythroid cells (1999) (16)
- SOCS1 is significantly up-regulated in Nutlin-3-treated p53wild-type B chronic lymphocytic leukemia (B-CLL) samples and shows an inverse correlation with miR-155 (2012) (16)
- Human herpesvirus 7 infection impairs the survival/differentiation of megakaryocytic cells. (2002) (16)
- Presence and characteristics of circulating megakaryocyte progenitor cells in human fetal blood. (1993) (16)
- Progressive and selective impairment of IL-3 and IL-4 production by peripheral blood CD4+ T-lymphocytes during the course of HIV-1 infection. (1992) (16)
- Combined treatment of CpG‐oligodeoxynucleotide with Nutlin‐3 induces strong immune stimulation coupled to cytotoxicity in B‐chronic lymphocytic leukemic (B‐CLL) cells (2008) (15)
- Impairment of GM‐CSF production in myelodysplastic syndromes (1993) (15)
- Merkel-cell polyomavirus (MCPyV) is rarely associated to B-chronic lymphocytic leukemia (1 out of 50) samples and occurs late in the natural history of the disease. (2012) (15)
- The CD4 receptor plays essential but distinct roles in HIV‐1 infection and induction of apoptosis in primary bone marrow GPIIb/IIIa+ megakaryocytes and the HEL cell line (1995) (15)
- Characterization of the effects of two polysulfonated distamycin A derivatives, PNU145156E and PNU153429, on HIV type 1 Tat protein. (1998) (15)
- Lineage‐related susceptibility of human hemopoietic cell lines to apoptosis (1999) (15)
- Stroma‐derived factor 1α induces a selective inhibition of human erythroid development via the functional upregulation of Fas/CD95 ligand (2000) (15)
- Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model (2014) (15)
- Extracellular Tat activates c‐fos promoter in low serum‐starved CD4+ T cells (2001) (15)
- Sex/Gender-Specific Imbalance in CVD: Could Physical Activity Help to Improve Clinical Outcome Targeting CVD Molecular Mechanisms in Women? (2020) (15)
- Tiazofurin induces a down-modulation of ICAM-1 expression on K562 target cells impairing NK adhesion and killing. (1995) (14)
- In vitro inhibition of interferon alpha-2a antiproliferative activity by antibodies developed during treatment for essential thrombocythaemia. (1992) (14)
- A role of the TRAIL-TRAIL receptor system in the pathogenesis of diabetes. (2007) (14)
- Healthy CD4+ T lymphocytes are not affected by targeted therapies against the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia (2016) (14)
- Nutlin-3 upregulates the expression of Notch 1 in both myeloid and lymphoid leukemic cells , as part of a negative feedback anti-apoptotic mechanism Running title : Nutlin-3 upregulates Notch 1 expression (2009) (14)
- The First Trimester Gravid Serum Regulates Procalcitonin Expression in Human Macrophages Skewing Their Phenotype In Vitro (2014) (14)
- TRAIL as biomarker and potential therapeutic tool for cardiovascular diseases. (2012) (14)
- Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients (2020) (13)
- Conjunctival sac fluid contains elevated levels of soluble TRAIL: Implications for the anti‐tumoral surveillance of the anterior surface of the eye (2009) (13)
- Inverse correlation between circulating levels of TNF-related apoptosis-inducing ligand and 17β-estradiol. (2014) (13)
- TRAIL administration down-modulated the acute systemic inflammatory response induced in a mouse model by muramyldipeptide or lipopolysaccharide. (2012) (13)
- The energy balance positively regulates the levels of circulating TNF-related apoptosis inducing ligand in humans. (2012) (13)
- Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease (2018) (13)
- Activation of the p53 pathway induces α‐smooth muscle actin expression in both myeloid leukemic cells and normal macrophages (2012) (13)
- Exposure of B cell chronic lymphocytic leukemia (B-CLL) cells to nutlin-3 induces a characteristic gene expression profile, which correlates with nutlin-3-mediated cytotoxicity. (2009) (13)
- TRAIL activates a caspase 9/7-dependent pathway in caspase 8/10-defective SK-N-SH neuroblastoma cells with two functional end points: induction of apoptosis and PGE2 release. (2003) (13)
- Lovastatin Dose-Dependently Potentiates the Pro-inflammatory Activity of Lipopolysaccharide Both In Vitro and In Vivo (2013) (12)
- Emerin presence in platelets (2000) (12)
- State of the art of the therapeutic perspective of sorafenib against hematological malignancies. (2012) (12)
- Different levels of the neuronal nitric oxide synthase isoform modulate the rate of osteoclastic differentiation of TIB-71 and CRL-2278 RAW 264.7 murine cell clones. (2005) (12)
- Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment (2016) (11)
- Perifosine selectively induces cell cycle block and modulates retinoblastoma and E2F1 protein levels in p53 mutated leukemic cell lines (2011) (11)
- Potential role of TRAIL in the management of autoimmune diabetes mellitus. (2012) (11)
- Human T-lymphocyte-derived megakaryocyte colony-stimulating activity. (1987) (11)
- Modulation of the expression and activity of cyclooxygenases in normal and accelerated erythropoiesis. (2004) (11)
- All‐trans retinoic acid at low concentration directly stimulates normal adult megakaryocytopoiesis in the presence of thrombopoietin or combined cytokines (1999) (11)
- Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B‐CLL) cells showing high versus low levels of Zap‐70 (2007) (11)
- PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines (2017) (11)
- The puzzling role of TRAIL in endothelial cell biology. (2007) (11)
- In Vitro Endothelial Cell Proliferation Assay Reveals Distinct Levels of Proangiogenic Cytokines Characterizing Sera of Healthy Subjects and of Patients with Heart Failure (2014) (11)
- HIV‐1 gp120 induces the activation of both c‐fos and c‐jun immediate‐early genes in HEL megakaryocytic cells (1999) (11)
- The γ-secretase inhibitors enhance the anti-leukemic activity of ibrutinib in B-CLL cells. (2017) (10)
- Perifosine plus nutlin‐3 combination shows a synergistic anti‐leukaemic activity (2010) (10)
- Differential activity of saporin 6 on normal and leukemic hemopoietic cells. (1989) (10)
- Release of a specific set of proinflammatory adipokines by differentiating 3T3-L1 cells. (2013) (10)
- Stromal derived factor-1α induces apoptosis in activated primary CD4+ T cells (2000) (10)
- Presence of CTAK/CCL27, MCP-3/CCL7 and LIF in human colostrum and breast milk. (2013) (10)
- Effects of Hypoxia and Bed Rest on Markers of Cardiometabolic Risk: Compensatory Changes in Circulating TRAIL and Glutathione Redox Capacity (2018) (10)
- Selective induction of TP53I3/p53‐inducible gene 3 (PIG3) in myeloid leukemic cells, but not in normal cells, by Nutlin‐3 (2014) (10)
- Hyperimmunoglobulinemia in HIV-1 infected individuals does not clearly correlate with plasma levels of IL-6. (1992) (9)
- Nanoparticles loaded with Nutlin-3 display cytotoxicity towards p53(wild-type) JVM-2 but not towards p53(mutated) BJAB leukemic cells. (2013) (9)
- The tumour necrosis factor-related apoptosis-inducing ligand-osteoprotegerin system in limited systemic sclerosis: a new disease marker? (2010) (9)
- Circulating TRAIL Shows a Significant Post-Partum Decline Associated to Stressful Conditions (2011) (9)
- The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias (2014) (9)
- The γ-secretase inhibitors enhance the anti-leukemic activity of ibrutinib in B-CLL cells (2017) (9)
- Selection and Characterization of a Novel Agonistic Human Recombinant Anti-Trail-R2 Minibody with Antileukemic Activity (2009) (9)
- TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress (2018) (9)
- Effect of Human Immunodeficiency Virus Type 1 on CD34+ Cells a (1991) (9)
- Dexamethasone counteracts the anti‐osteoclastic, but not the anti‐leukemic, activity of TNF‐related apoptosis inducing ligand (TRAIL) (2010) (9)
- The expression levels of the pro-apoptotic XAF-1 gene modulate the cytotoxic response to Nutlin-3 in B chronic lymphocytic leukemia (2010) (8)
- TRAIL counteracts the pro-adhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release Short title: Anti-adhesive activity of TRAIL (2005) (8)
- Autoinflammatory Diseases and Cytokine Storms—Imbalances of Innate and Adaptative Immunity (2021) (8)
- Soluble TRAIL does not impair the anti-osteoclastic activity of osteoprotegerin (2008) (8)
- CD4 engagement by HIV-1 in TF-1 hematopoietic progenitor cells increases protein kinase C activity and reduces intracellular Ca2+ levels. (1994) (8)
- Human immunodeficiency virus type 1 (HIV-1) and human hematopoietic progenitor cells (2005) (8)
- Inhibitory effect of HIV-1 envelope glycoproteins gp120 and gp160 on the in vitro growth of enriched (CD34+) hematopoietic progenitor cells (2005) (8)
- HIV-1 infection and hematologic picture. (1991) (8)
- Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS) (2019) (7)
- The early determination of circulating TRAIL levels does not predict the development of pre-eclampsia. (2012) (7)
- Soluble TRAIL is present at high concentrations in seminal plasma and promotes spermatozoa survival. (2014) (7)
- The Italian law on body donation: A position paper of the Italian College of Anatomists. (2021) (7)
- MCL1 down‐regulation plays a critical role in mediating the higher anti‐leukaemic activity of the multi‐kinase inhibitor Sorafenib with respect to Dasatinib (2012) (7)
- Decreased levels of soluble TNF‐related apoptosis‐inducing ligand (TRAIL) in the conjunctival sac fluid of patients with diabetes affected by proliferative retinopathy (2011) (7)
- p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics) (2022) (7)
- Phospholipase C δ2 Expression Characterizes the Neoplastic Transformation of the Human Gastric Mucosa (2001) (7)
- Serum TRAIL levels increase shortly after insulin therapy and metabolic stabilization in children with type 1 diabetes mellitus (2015) (6)
- TNF-Related Apoptosis Inducing Ligand in Ocular Cancers and Ocular Diabetic Complications (2015) (6)
- GM-CSF production by CD4+ T-lymphocytes is selectively impaired during the course of HIV-1 infection. A possible indication of a preferential lesion of a specific subset of peripheral blood CD4+ T-lymphocytes. (1992) (6)
- Human Immunodeficiency Virus Type 1 Nef Protein Sensitizes CD 4 1 T Lymphoid Cells to Apoptosis via Functional Upregulation of the CD 95 / CD 95 Ligand Pathway (1999) (6)
- Hiv-1 tat protein suppresses the nerve growth-factor (ngf)-mediated differentiation of PC12 rat pheochromocytoma cell-line. (1994) (6)
- ARHGDIA, a mutant TP53‐associated Rho GDP dissociation inhibitor, is over‐expressed in gene expression profiles of TP53 disrupted chronic lymphocytic leukaemia cells (2013) (6)
- The impaired number of circulating granulocyte/macrophage progenitors (CFU-GM) in human immunodeficiency virus-type 1 infected subjects correlates with an active HIV-1 replication (2005) (6)
- Cancer Therapy : Preclinical Dasatinib Plus Nutlin-3 Shows Synergistic Antileukemic Activity in Both p 53 wild-type and p 53 mutated B Chronic Lymphocytic Leukemias by Inhibiting the Akt Pathway (2011) (6)
- Reduced bone marrow colony growth in hairy-cell leukemia before and after interferon-alpha treatment. Possible inhibitory role of a serological factor. (1988) (6)
- Mesenchymal stem cells display hepato-protective activity in lymphoma bearing xenografts (2012) (6)
- Circulating levels of frizzled-related protein (FRZB) are increased in patients with early rheumatoid arthritis and decrease in response to disease-modifying antirheumatic drugs (2010) (6)
- Levels of TNF-Related Apoptosis-Inducing Ligand (TRAIL) Show a Long-term Stability in the Breast Milk of Mothers of Preterm Infants (2013) (5)
- Letter by Secchiero and Zauli regarding article, "Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice". (2008) (5)
- In vivo anti-lymphoma activity of an agonistic human recombinant anti-TRAIL-R2 minibody (2012) (5)
- Hydrogen sulfide down-regulates the expression and release of osteoprotegerin (OPG) by vascular endothelial cells (2012) (5)
- Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women (2017) (5)
- Enforced expression of human bcl‐2 in CD4+ T cells enhances human herpesvirus 7 replication and induction of cytopathic effects (1998) (5)
- Molecular targets for selective killing of TRAIL-resistant leukemic cells (2011) (5)
- JCV+ Patients with Inflammatory bowel disease show elevated plasma levels of MIG and SCF. (2012) (4)
- The engagement of CD4 surface antigen in the HEL haemopoietic cell line up‐regulates the transforming growth factor‐β1 (TGF‐β1) promoter activity (1997) (4)
- Stromal derived factor-1alpha induces apoptosis in activated primary CD4+ T cells. (2000) (4)
- TRAIL treatment prevents renal morphological changes and TGF-β-induced mesenchymal transition associated with diabetic nephropathy. (2020) (4)
- Unsung Hero Robert C. Gallo (2009) (4)
- The elevation of circulating platelets after IFN-alpha therapy in HIV-1 seropositive thrombocytopenic patients correlates with increased plasma levels of IL-6. (1993) (4)
- Tumor Necrosis Factor ( TNF-) Activates Jak 1 / Stat 3-Stat 5 B Signaling through TNFR-1 in Human B Cells 1 (2002) (4)
- The non-genotoxic activator of the p53 pathway Nutlin-3 shifts the balance between E2F7 and E2F1 transcription factors in leukemic cells (2013) (4)
- A brain hidden in Ferrara cathedral: a novel interpretation of a Renaissance masterpiece. (2019) (3)
- Therapeutic potential of the MDM2 inhibitor Nutlin-3 in counteracting SARS-CoV-2 infection of the eye through p53 activation (2022) (3)
- Heterogeneity of mesenchymal stromal cells in lymphoproliferative disorders. (2014) (3)
- Effect of in vivo treatment with rh GM-CSF on in vitro growth of haematopoietic progenitors in patients with myelodysplastic syndromes. (1992) (3)
- Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes (2022) (3)
- Immunoblotting analysis of IgA and IgM antibody to human immunodeficiency virus type 1 (HIV-1) polypeptides in seropositive infants (2005) (3)
- All-trans retinoic acid potentiates megakaryocyte colony formation: in vitro and in vivo effects after administration to acute promyelocytic leukemia patients. (1994) (3)
- Flow cytometric quantification of HIV-1 Tat protein in tat-transfected Jurkat T cell lines. (1998) (3)
- Human Cancer Biology miR-34 a Induces the Downregulation of Both E 2 F 1 and B-Myb Oncogenes in Leukemic Cells (2011) (3)
- Role of TRAIL in osteoclastogenesis (2008) (3)
- Reduced expression of cell cycle‐associated genes in B lymphocytes purified from the peripheral blood of early‐stage B chronic lymphocytic leukaemia patients (2009) (3)
- TRAIL, a New Weapon against Neointimal Hyperplasia (2012) (3)
- In vivo and in vitro modulatory effect of human immunodeficiency virus type-1 (HIV-1) Tat protein on protein kinase C activity. (1996) (3)
- Extracellular HIV-1 Tat protein activates the transcriptional repressor inducible cAMP early repressor in both the Jurkat cell line and primary peripheral blood mononuclear cells. (2000) (3)
- Circulating levels of TNF‐related apoptosis inducing ligand (TRAIL) (2014) (2)
- Absence of HTLV-I/II infection in blood donors with positive and inconclusive HTLV-I/II serology. (1992) (2)
- The circulating levels of TRAIL are extremely low after delivery but rapidly recover in both mothers and newborns. (2013) (2)
- Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy (2015) (2)
- Apoptosis vs Necrosis (2011) (2)
- Enforced expression of human bcl-2 in CD4+ T cells enhances human herpesvirus 7 replication and induction of cytopathic effects. (1998) (2)
- B-Cell Chronic Lymphocytic Leukemia Cells Exposed to the Non-Genotoxic p53 Activator Nutlin-3 Are Characterized by a Specific Gene Expression Signature. (2009) (2)
- Phospholipase C delta2 expression characterizes the neoplastic transformation of the human gastric mucosa. (2001) (2)
- pathway TRAIL regulates normal erythroid maturation through an ERK-dependent (2013) (2)
- Infection of CD34+ hematopoietic progenitor cells by human herpesvirus 7 (HHV-7) (2000) (2)
- Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors (2021) (2)
- Sorafenib inhibits in vitro osteoclastogenesis by down-modulating Mcl-1 (2013) (2)
- Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells (2022) (2)
- Human T-lymphotropic virus type I (HTLV-I) provirus-related DNA sequences in peripheral blood mononuclear cells of a patient, in the absence of a definite serological positivity. (1993) (2)
- Impaired Regulation of Megakaryocytopoiesis in Essential Thrombocythemia (1991) (2)
- Association between thyroid hormones and TRAIL. (2017) (2)
- Inhibition of Purified CD 34 + Hematopoietic Progenitor Cells by Human ImmunodeficiencyVirus 1 or gp 120 Mediated by Endogenous Transforming Growth Factor (2003) (1)
- Clinical perspectives of TRAIL: insights into central nervous system disorders (2016) (1)
- Simultaneous determination of multiple cytokines reveals a pro-inflammatory and pro-angiogenic signature after major cardiothoracic surgery: potential role of C-reactive protein. (2012) (1)
- Flow cytometry in situ polymerase chain reaction as an innovative approach to HIV-1 proviral DNA detection. (1998) (1)
- Selective enrichment in human megakaryocyte progenitors by the B203.13 surface differentiation antigen (1997) (1)
- The negative prognostic value of TRAIL overexpression in oral squamous cell carcinomas does not preclude the potential therapeutic use of recombinant TRAIL (2012) (1)
- Accuracy of intraocular lens power calculation for cataract surgery after deep anterior lamellar keratoplasty (2021) (1)
- Editorial: Innovative therapeutical approaches for hematological malignancies based on molecular targeted therapies. (2008) (1)
- Author Correction: HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts (2020) (1)
- hematopoietic progenitors in Diamond-Blackfan anemia In vitro growth and regulation of bone marrow enriched CD34+ (2011) (1)
- Association of Serum Tumor Necrosis Factor-Related Apoptosis Inducing Ligand with Body Fat Distribution as Assessed by Dual X-Rays Absorptiometry (2014) (1)
- TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake (2021) (1)
- TNF-related apoptosis-inducing ligand (TRAIL) induces monocytic maturation of both leukemic and normal myeloid precursors via a caspase-dependent pathway Running title: Maturative effects of TRAIL Scientific Section Heading: Hematopoiesis (2002) (1)
- Two‑gene mutation in a single patient: Biochemical and functional analysis for a correct interpretation of exome results. (2015) (1)
- Different responsiveness of normal and leukemic hemopoietic cells to esorubicin. (1988) (1)
- Both Resting and CD 3-Stimulated CD 4 Chemokine Receptor 4 Surface Expression in Engagement of CD 28 Modulates CXC (2000) (1)
- DIFFERENTIAL REGULATION OF BCL-2 AND C-FOS GENES BY HIV-1 TAT PROTEIN IN SERUM-STARVED AND ACTIVATED LYMPHOID T CELLS (1996) (0)
- virus-type 1 levels of CD4, the high-affinity receptor for human immunodeficiency A subset of human CD34+ hematopoietic progenitors express low (2011) (0)
- PI3K/Akt/mTOR Pathway in Acute Lymphoblastic Leukemia Targeted Therapies (2019) (0)
- Therapeutic contact lens‐assisted optical coherence tomography for detection of posterior segment diseases in patients with corneal oedema (2022) (0)
- Abstract B46: Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent AKT reactivation (2015) (0)
- In vitro models of osteoclastogenesis: morphology and growth characteristics of two RAW 264.7 clones. (2004) (0)
- Treatment based on Nutlin-3 combinations as innovative therapy for leucemia and pediatric malignancies (2012) (0)
- Contents Vol. 41, 2016 (2016) (0)
- Origin and tillering of maize. (1970) (0)
- Editorial: Cell cycle control as a new therapeutic approach for SARS-CoV-2 infection (2023) (0)
- TRAIL treatment reduces high-fat diet-induced hyperglycemia and hyperinsulinemia (2016) (0)
- Regulation of osteoclast differentiation and maturation: crosstalk between immunitary system and bone (2006) (0)
- Secchiero et al. CCR-12-3027.R2 C reactive protein down-regulates TNF-related apoptosis inducing ligand expression in human peripheral monocytes via an Egr-1 dependent pathway Running Title: Down-regulation of TRAIL by CRP (2013) (0)
- [Essential thrombocythemia: in vitro study of megakaryocytopoiesis]. (1991) (0)
- Merkel-Cell Polyomavirus Is Rarely Associated to B-Chronic Lymphocytic Leukemia and Occurs Late in the Natural History of the Disease (2012) (0)
- Thyroid hormones influence the expression of TNF-related apoptosis-inducing ligand (2015) (0)
- Early pregnancy Soluble TRAIL is elevated in recurrent miscarriage and inhibits the in vitro adhesion and migration of HTR 8 trophoblastic cells (2012) (0)
- Receptor 4 in Resting CD 4 the Expression of Surface CXC-Chemokine Extracellular HIV-1 Tat Protein UpRegulates Gallo and (1999) (0)
- Abstract A34: Therapeutic potential of the novel mTOR inhibitor Torin-2 to overcome AKT reactivation in B-precursor acute lymphoblastic leukemia (B-pre ALL). (2015) (0)
- Editorial: innovative therapeutic approaches for the treatment of pediatric autoimmune and inflammatory diseases. (2012) (0)
- The long and winding road may be getting shorter (2005) (0)
- Running title: Nutlin-3 upregulates Notch1 expression (2016) (0)
- HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts (2018) (0)
- Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway and NUP214-ABL1 fusion protein in human acute lymphoblastic leukemia (2016) (0)
- The Human Immunodeficiency Virus Type-l Tat Protein Upregulates Bcl-2 Gene Expression in Jurkat T-cell Lines and Primary Peripheral Blood Mononuclear Cells (2002) (0)
- 4.9 Detection of p53 Dysfunction in Chronic Lymphocytic Leukemia by an In Vitro Functional Assay Based on p53 Activation by the Nongenotoxic Drug Nutlin-3 (2011) (0)
- Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL (2022) (0)
- Role of HIV-1 in the Functional Impairment of CD34+ Hematopoietic Progenitor Cells (1996) (0)
- HIV-1 induces primary CD34+ hematopoietic progenitors and HEL cells to release autocrine TGF-β1 (1996) (0)
- Editor's Note: The Oncogene DEK Promotes Leukemic Cell Survival and Is Downregulated by Both Nutlin-3 and Chlorambucil in B-Chronic Lymphocytic Leukemic Cells. (2022) (0)
- Tillering and the origins of maize. (1970) (0)
- Blood Mononuclear Cells Lymphoblastoid T Cells and Primary Peripheral CREB Transcription Factor in Both Jurkat Phosphorylation and Activation of 133 Rapid Ser Extracellular HIV-1 Tat Protein Induces the (1998) (0)
- Influence of physical factors and systemic fungicides on the germinability of barley seeds. (1990) (0)
- Editor's Note: Nanoparticles Engineered with Rituximab and Loaded with Nutlin-3 Show Promising Therapeutic Activity in B-Leukemic Xenografts. (2022) (0)
- Human immunodeficiency virus type 1 interaction with the membrane of CD 4 ÷ cells induces the synthesis and nuclear translocation of 70 K heat shock protein (2007) (0)
- Merkel-cell polyomavirus and B-cell chronic lymphocytic leukemia (2012) (0)
- MDM2 inhibitors-mediated disruption of mitochondrial metabolism: A novel therapeutic strategy for retinoblastoma (2022) (0)
- Circulating levels of TNF-related apoptosis inducing-ligand are decreased in patients with large adult-type granulosa cell tumors—implications for therapeutic potential (2016) (0)
- Supplementary Material for: Serum Soluble Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Levels in Older Subjects with Dementia and Mild Cognitive Impairment (2016) (0)
- In vitro a poptos is of senescent human megakaryocytes (1997) (0)
- OSTEOPROTEGERIN INJECTION INDUCES MORPHOLOGICAL AND FUNCTIONAL ALTERATIONS IN MOUSE PANCREATIC ISLETS (2020) (0)
- Potential involvement of TRAIL in Treg cell-mediated osteoclast suppression: comment on the article by Zaiss et al. (2008) (0)
- differentiation induced by RANKL+M-CSF TNF-related apoptosis inducing ligand (TRAIL) blocks osteoclastic (2013) (0)
- Running title: Rituximab plus Nutlin-3 loaded nanoparticles (2013) (0)
- Erratum: Flow cytometric quantification of HIV-1 Tat protein in tat- transfected Jurkat T cell lines (Journal of Immunological Methods (1998) 221 (107-117) PII: S0022175998001690) (1999) (0)
- NF-κB pathways in hematological malignancies (2014) (0)
- Cancer Therapy : Preclinical Nutlin-3 Downregulates the Expression of the Oncogene TCL 1 in Primary B Chronic Lymphocytic Leukemic Cells (2011) (0)
- Author Correction: HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts (2020) (0)
- in vitro and in vivo Osteoprotegerin increases leukocyte adhesion to endothelial cells both (2013) (0)
- Three hits are superior than one: multiple Akt inhibition as a new therapeutic strategy in T-ALL (2015) (0)
- Innovative approaches for the management of pediatric malignancies. (2013) (0)
- Subcellular localization of the regulatory HIV-I tat protein produced endogenously by or added exogenously to PC12 rat pheochromocytoma and human jurkat T lymphoid cells (1996) (0)
- Cytotoxic activity of the novel dual PI3K/mTOR inhibitor NVP-BGT226 in both normoxic and hypoxic hepatocarcinoma cells (2015) (0)
- Editor's Note: Dasatinib Plus Nutlin-3 Shows Synergistic Antileukemic Activity in Both p53wild-type and p53mutated B Chronic Lymphocytic Leukemias by Inhibiting the Akt Pathway. (2022) (0)
- Phospholipase C (cid:1) 2 Expression Characterizes the Neoplastic Transformation of the Human Gastric Mucosa (2001) (0)
- Effects of TRAIL delivery on an experimental model of type 2 diabetes and diabetic nephropathy (2018) (0)
- Aberrant Expression of Trail in B Chronic Lymphocytic Leukemia (B-CLL) Cells. (2005) (0)
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What Schools Are Affiliated With Giorgio Zauli?
Giorgio Zauli is affiliated with the following schools:
