Giuseppe Poli
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Giuseppe Polibiology Degrees
Biology
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Molecular Biology
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Neuroscience
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Biochemistry
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Biology
Giuseppe Poli's Degrees
- PhD Biochemistry University of California, Berkeley
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(Suggest an Edit or Addition)Giuseppe Poli's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- IKK-β links inflammation to obesity-induced insulin resistance (2005) (990)
- IKK-beta links inflammation to obesity-induced insulin resistance. (2005) (925)
- Oxidative stress and cell signalling. (2004) (702)
- Pathogenesis of liver fibrosis: role of oxidative stress. (2000) (622)
- Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes. (1982) (551)
- Oxidative damage and fibrogenesis. (1997) (501)
- 4‐Hydroxynonenal: A membrane lipid oxidation product of medicinal interest (2008) (392)
- Pathological aspects of lipid peroxidation (2010) (384)
- Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions. (1985) (345)
- Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. (1993) (343)
- The role of lipid peroxidation in liver damage. (1987) (327)
- Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury. (2004) (307)
- 4‐Hydroxynonenal in the Pathomechanisms of Oxidative Stress (2000) (300)
- HNE interacts directly with JNK isoforms in human hepatic stellate cells. (1998) (290)
- Heavy metal effects on lipid peroxidation in the tissues of mytilus gallopro vincialis lam. (1990) (272)
- The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis 1 (1997) (269)
- Tumor suppressor genes and ROS: complex networks of interactions. (2012) (268)
- Liver damage due to free radicals. (1993) (256)
- Vitamin E dietary supplementation protects against carbon tetrachloride—induced chronic liver damage and cirrhosis (1992) (249)
- Oxysterols in the pathogenesis of major chronic diseases☆ (2013) (236)
- Lipid oxidation products in cell signaling. (2000) (214)
- Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review). (2002) (183)
- Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets. (2013) (181)
- Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid. (1996) (180)
- On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis. (1996) (178)
- The Lipid Peroxidation Product 4‐Hydroxy‐2,3‐Nonenal Increases AP‐1‐Binding Activity Through Caspase Activation in Neurons (2000) (175)
- Microvascular dysfunction induced by reperfusion injury and protective effect of ischemic preconditioning. (2002) (166)
- Free Radicals: from Basic Science to Medicine (1993) (159)
- Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation (2016) (156)
- 4-Hydroxynonenal-protein adducts: A reliable biomarker of lipid oxidation in liver diseases. (2008) (152)
- Vitamin E dietary supplementation inhibits transforming growth factor β1 gene expression in the rat liver (1992) (147)
- 4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis. (2005) (143)
- Signaling kinases modulated by 4-hydroxynonenal. (2004) (139)
- Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress (2004) (139)
- Hepatic stellate cell: a star cell in the liver. (2009) (132)
- Calorie restriction and dietary restriction mimetics: a strategy for improving healthy aging and longevity. (2014) (131)
- Oxidized cholesterol as the driving force behind the development of Alzheimer’s disease (2015) (129)
- Studies on fatty liver with isolated hepatocytes. II. The action of carbon tetrachloride on lipid peroxidation, protein, and triglyceride synthesis and secretion. (1979) (126)
- Design and development of nanovehicle-based delivery systems for preventive or therapeutic supplementation with flavonoids. (2010) (126)
- Cholesterol oxidation products in the vascular remodeling due to atherosclerosis. (2009) (124)
- Lipid peroxidation and irreversible damage in the rat hepatocyte model. Protection by the silybin-phospholipid complex IdB 1016. (1992) (124)
- Polyphenol supplementation as a complementary medicinal approach to treating inflammatory bowel disease. (2011) (122)
- Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry. (2009) (114)
- Ischemic preconditioning: a defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion1 (2002) (107)
- The link between altered cholesterol metabolism and Alzheimer's disease (2012) (106)
- Oxidative stress and kidney dysfunction due to ischemia/reperfusion in rat: attenuation by dehydroepiandrosterone. (2003) (102)
- Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability (2015) (101)
- Oxysterol mixtures prevent proapoptotic effects of 7‐ ketocholesterol in macrophages: implications for proatherogenic gene modulation (2004) (99)
- Inflammation-related gene expression by lipid oxidation-derived products in the progression of atherosclerosis. (2012) (97)
- Reperfusion damage to the bile canaliculi in transplanted human liver (1996) (96)
- Xanthine oxidase-induced oxidative stress causes activation of NF-kappaB and inflammation in the liver of type I diabetic rats. (2010) (95)
- Regulation of rat hepatocyte protein kinase C β isoenzymes by the lipid peroxidation product 4‐hydroxy‐2,3‐nonenal: A signaling pathway to modulate vesicular transport of glycoproteins (1999) (95)
- Paracetamol-stimulated lipid peroxidation in isolated rat and mouse hepatocytes. (1983) (92)
- Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells. (1994) (91)
- Mitochondrial function in liver disease. (2007) (90)
- Scavenging effect of silipide, a new silybin-phospholipid complex, on ethanol-derived free radicals. (1995) (90)
- Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation. (2010) (86)
- Interaction between 24‐hydroxycholesterol, oxidative stress, and amyloid‐β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime (2011) (84)
- Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells. (2005) (81)
- Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol. (2006) (81)
- Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol (2014) (80)
- Free Radical Scavenging and Antioxidative Properties of ‘Silibin’ Complexes on Microsomal Lipid Peroxidation (1997) (80)
- Targeting tissue oxidative damage by means of cell signaling modulators: the antioxidant concept revisited. (2010) (78)
- The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons. (2000) (76)
- Lipid Oxidation Derived Aldehydes and Oxysterols Between Health and Disease (2019) (76)
- Comparative evaluation of the antioxidant activity of α-tocopherol, α-tocopherol polyethylene glycol 1000 succinate and α-tocopherol succinate in isolated hepatocytes and liver microsomal suspensions (1990) (76)
- Associated changes of lipid peroxidation and transforming growth factor β1 levels in human colon cancer during tumour progression (2002) (76)
- AT1 receptor antagonist Candesartan in selected cirrhotic patients: effect on portal pressure and liver fibrosis markers. (2007) (75)
- Oxysterols: An emerging class of broad spectrum antiviral effectors. (2016) (74)
- Lipid peroxidation and molecular damage to polyunsaturated fatty acids in rat liver. Recognition of two classes of hydroperoxides formed under conditions in vivo. (1986) (74)
- Wine consumption and intestinal redox homeostasis (2014) (73)
- Up‐regulation of the fibrogenic cytokine TGF‐β1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis (2001) (71)
- Loading into Nanoparticles Improves Quercetin's Efficacy in Preventing Neuroinflammation Induced by Oxysterols (2014) (68)
- Studies on the antioxidant and free radical scavenging properties of IdB 1016 a new flavanolignan complex. (1990) (68)
- Studies on fatty liver with isolated hepatocytes. I. The action of colchicine, phalloidin, cytochalasin B, and cyclohexamide on protein and triglyceride synthesis and secretion. (1977) (66)
- Proinflammatory effect of cholesterol and its oxidation products on CaCo-2 human enterocyte-like cells: effective protection by epigallocatechin-3-gallate. (2010) (64)
- The role of lipid peroxidation in CCl4-induced damage to liver microsomal enzymes: comparative studies in vitro using microsomes and isolated liver cells. (1981) (63)
- Pro-oxidant and proapoptotic effects of cholesterol oxidation products on human colonic epithelial cells: a potential mechanism of inflammatory bowel disease progression. (2009) (62)
- Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy-2,3-nonenal and other 4-hydroxy-2,3-alkenals is related to their molecular structure. (1996) (62)
- Effects of carbon tetrachloride on isolated rat hepatocytes. Inhibition of protein and lipoprotein secretion. (1979) (62)
- Free radical metabolism of alcohols by rat liver microsomes. (1987) (60)
- Biogenic 4‐hydroxy‐2‐nonenal activates transcription factor AP‐1 but not NF‐κB in cells of the macrophage lineage (1997) (59)
- Glutathione depletion induces apoptosis of rat hepatocytes through activation of protein kinase C novel isoforms and dependent increase in AP-1 nuclear binding. (2000) (58)
- The role of oxysterols in vascular ageing (2016) (58)
- An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples (2010) (58)
- Lipid Oxidation Products in the Pathogenesis of Inflammation-related Gut Diseases. (2017) (57)
- Possible role of aldehydic lipid peroxidation products as chemoattractants. (1987) (57)
- In vivo and in vitro evidence concerning the role of lipid peroxidation in the mechanism of hepatocyte death due to carbon tetrachloride (1991) (56)
- The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients (2020) (56)
- Inflammatory and redox reactions in colorectal carcinogenesis (2015) (55)
- In situ determination by surface chemiluminescence of temporal relationships between evolving warm ischemia‐reperfusion injury in rat liver and phagocyte activation and recruitment (2000) (55)
- Calorie restriction protects against age‐related rat aorta sclerosis (2005) (55)
- Dietary lipids and their oxidized products in Alzheimer's disease. (2011) (54)
- Ischemic preconditioning attenuates the oxidant‐dependent mechanisms of reperfusion cell damage and death in rat liver (2002) (53)
- Implication of oxysterols in chronic inflammatory human diseases. (2018) (53)
- c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa. (2006) (52)
- Lipid peroxidation in human diseases: evidence of red cell oxidative stress after circulatory shock. (1989) (51)
- 4-hydroxynonenal and transforming growth factor-beta1 expression in colon cancer. (2003) (50)
- Activation of PKC-β isoforms mediates HNE-induced MCP-1 release by macrophages (2002) (49)
- Oxygen free radical scavenger properties of dehydroepiandrosterone (1998) (49)
- Free radicals in the pathogenesis of liver injury : proceedings of the Second Congress on Free Radicals in Liver Injury, 9-11 June 1988, Turin, Italy (1989) (49)
- Oxidative damage and transforming growth factor beta 1 expression in pretumoral and tumoral lesions of human intestine. (1997) (48)
- Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions. (2011) (48)
- Resveratrol protects against 4-hydroxynonenal-induced apoptosis by blocking JNK and c-JUN/AP-1 signaling. (2006) (48)
- Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine (2014) (47)
- Synergistic interaction of fatty acids and oxysterols impairs mitochondrial function and limits liver adaptation during nafld progression (2017) (47)
- Role of PKC-δ activity in glutathione-depleted neuroblastoma cells (2003) (45)
- 25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes (2018) (43)
- Oxysterols and 4‐hydroxy‐2‐nonenal contribute to atherosclerotic plaque destabilization (2017) (41)
- Lipid peroxidation and covalent binding in the early functional impairment of liver golgi apparatus by carbon tetrachloride (1990) (41)
- Resveratrol protects against 4‐HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts (2004) (41)
- Carbon tetrachloride-induced inhibition of hepatocyte lipoprotein secretion: functional impairment of Golgi apparatus in the early phases of such injury. (1985) (40)
- Neutrophil Recruitment in the Reperfused-Injured Rat Liver was Effectively Attenuated by Repertaxin, a Novel Allosteric Noncompetitive Inhibitor of Cxcl8 Receptors: A Therapeutic Approach for the Treatment of Post-Ischemic Hepatic Syndromes (2005) (40)
- Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation. (2014) (40)
- Cholesterol and Alzheimer's disease: A still poorly understood correlation (2012) (40)
- Free Radicals in Brain Pathophysiology (2000) (40)
- Postprandial Dysmetabolism and Oxidative Stress in Type 2 Diabetes: Pathogenetic Mechanisms and Therapeutic Strategies (2015) (39)
- Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol (2017) (38)
- Phenolic compounds present in Sardinian wine extracts protect against the production of inflammatory cytokines induced by oxysterols in CaCo-2 human enterocyte-like cells. (2013) (38)
- The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics. (2015) (38)
- Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture (2008) (38)
- New insights into redox-modulated cell signaling. (2011) (38)
- Mechanisms responsible for carbon tetrachloride‐induced perturbation of mitochondrial calcium homeostasis (1985) (38)
- New Data on Kinetics of Lipid Peroxidation in Experimental Hepatomas and Preneoplastic Nodules (1986) (37)
- The contribution of animal fat oxidation products to colon carcinogenesis, through modulation of TGF-beta1 signaling. (2008) (37)
- Effects of dietary fatty acids and cholesterol excess on liver injury: A lipidomic approach (2016) (37)
- HNE and cholesterol oxidation products in colorectal inflammation and carcinogenesis (2017) (36)
- Trojan horse-like behavior of a biologically representative mixture of oxysterols. (2004) (35)
- Effects of carbon tetrachloride on calcium homeostasis. A critical reconsideration. (1989) (35)
- Progressive Increase of Matrix Metalloprotease-9 and Interleukin-8 Serum Levels during Carcinogenic Process in Human Colorectal Tract (2012) (35)
- Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line. (2013) (34)
- Toxicity of 1,2-dibromoethane in isolated hepatocytes: role of lipid peroxidation. (1984) (34)
- In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study. (1992) (34)
- Contribution of γ glutamyl transpeptidase to oxidative damage of ischemic rat kidney (2000) (34)
- Cholesterol and amyloid-β: evidence for a cross-talk between astrocytes and neuronal cells. (2011) (34)
- Oxysterols and mechanisms of survival signaling. (2016) (32)
- 4-Hydroxynonenal signalling to apoptosis in isolated rat hepatocytes: the role of PKC-delta. (2005) (32)
- Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride. (1999) (32)
- Activation of the mitochondrial pathway of apoptosis by oxysterols. (2007) (32)
- Oxidative stress in stable cystic fibrosis patients: do we need higher antioxidant plasma levels? (2013) (32)
- Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells. (2010) (31)
- Resistance to oxidative stress by hyperplastic and neoplastic rat liver tissue monitored in terms of production of unpolar and medium polar carbonyls. (1986) (31)
- Selenium and glutathione peroxidase variations induced by polyunsaturated fatty acids oral supplementation in humans. (1992) (30)
- A novel role of protein kinase C-δ in cell signaling triggered by glutathione depletion (2003) (30)
- Modulation of rat liver protein kinase C during "in vivo" CC14-induced oxidative stress. (1993) (29)
- Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. (2003) (28)
- Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways (2011) (27)
- Oxidative stress in the development of human ischemic hepatitis during circulatory shock. (1994) (27)
- Metabolism of 4‐hydroxynonenal by the rat heptoma cell line MH1C1 (1988) (26)
- Promethazine inhibits the formation of aldehydic products of lipid peroxidation but not covalent binding resulting from the exposure of rat liver fractions to CCl4. (1989) (26)
- Omics analysis of oxysterols to better understand their pathophysiological role. (2019) (26)
- Prevention of carbon tetrachloride-induced lipid peroxidation in liver microsomes from dehydroepiandrosterone-pretreated rats. (1994) (25)
- Lipid peroxidation in the reperfusion injury of the liver. (1998) (25)
- Derangement of intestinal epithelial cell monolayer by dietary cholesterol oxidation products (2017) (25)
- Lipid peroxidation and irreversible cell damage: synergism between carbon tetrachloride and 1,2-dibromoethane in isolated rat hepatocytes. (1991) (25)
- Further Experiments on Lipid Peroxidation in Transplanted and Experimental Hepatomas (1984) (24)
- Metalloproteinases and metalloproteinase inhibitors in age-related diseases. (2014) (24)
- Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage. (2001) (24)
- Effects of carbon tetrachloride on isolated rat liver cells: stimulation of lipid peroxidation and inhibitory action of free-radical scavengers [proceedings]. (1978) (23)
- 4-Hydroxynonenal is Markedly Higher in Patients on a Standard Long-term Home Parenteral Nutrition (2004) (22)
- A Dietary Mixture of Oxysterols Induces In Vitro Intestinal Inflammation through TLR2/4 Activation: The Protective Effect of Cocoa Bean Shells (2019) (22)
- Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment. (1998) (22)
- Carbon tetrachloride-induced inhibition of protein kinase C in isolated rat hepatocytes. (1988) (22)
- Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells. (2016) (21)
- Role of 4‐hydroxy‐2,3‐nonenal in the pathogenesis of fibrosis (2005) (21)
- Ischaemic preconditioning modulates the activity of Kupffer cells during in vivo reperfusion injury of rat liver (2003) (20)
- Hepatocellular metabolism of 4-hydroxy-2,3-nonenal is impaired in conditions of chronic cholestasis. (1995) (20)
- Antiviral oxysterols are present in human milk at diverse stages of lactation (2019) (19)
- 4‐Hydroxynonenal and TGF‐β1 concur in inducing antiproliferative effects on the Caco‐2 human colon adenocarcinoma cell line (2005) (19)
- Reduction of oxidative stress in adjuvant arthritis. Comparison of efficacy of two pyridoindoles: stobadine dipalmitate and SMe1.2HCl. (2010) (19)
- Increased production of 27‐hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration (2019) (18)
- The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer’s Disease (2021) (18)
- Metabolism of 4-hydroxy-2-nonenal and aging. (1995) (18)
- Stimulation of liver heme oxygenase in hexachlorobenzene-induced hepatic porphyria (1998) (18)
- Activation of PKC-beta isoforms mediates HNE-induced MCP-1 release by macrophages. (2002) (18)
- Expression and synthesis of TGFβ1 is induced in macrophages by 9‐oxononanoyl cholesterol, a major cholesteryl ester oxidation product (2005) (18)
- Ability of different hepatoma cells to metabolize 4‐hydroxynonenal (1993) (17)
- CCl4-induced increase of hepatocyte free arachidonate level: pathogenesis and contribution to cell death. (1990) (17)
- Inactivation of hepatocyte protein kinase C by carbon tetrachloride: involvement of drug's metabolic activation and prooxidant effect. (1990) (17)
- The role of autophagy in survival response induced by 27-hydroxycholesterol in human promonocytic cells (2018) (17)
- Pancreatic-carcinoma-cell-derived pro-angiogenic factors can induce endothelial-cell differentiation of a subset of circulating CD34+ progenitors (2013) (16)
- Down-modulation of nuclear localisation and pro-fibrogenic effect of 4-hydroxy-2,3-nonenal by thiol- and carbonyl-reagents. (2002) (16)
- Evidence of an increased nitric oxide production in primary biliary cirrhosis (2001) (16)
- A novel role of protein kinase C-delta in cell signaling triggered by glutathione depletion. (2003) (15)
- Enzymatic impairment induced by biological aldehydes in intact rat liver cells. (1982) (15)
- Effects of ethanol metabolism on PKC activity in isolated rat hepatocytes. (1996) (15)
- Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense (2019) (15)
- Tumor Necrosis Factor-α in Airway Secretions from Cystic Fibrosis Patients Upregulate Endothelial Adhesion Molecules and Induce Airway Epithelial Cell Apoptosis: Implications for Cystic Fibrosis Lung Disease (2008) (15)
- Biochemical evidence for chemical and/or topographic differences in the lipoperoxidative processes induced by CCl4 and iron. (1983) (15)
- Potentiation of amyloid-β peptide neurotoxicity in human dental-pulp neuron-like cells by the membrane lipid peroxidation product 4-hydroxynonenal. (2012) (14)
- Efficacy of theobromine in preventing intestinal CaCo-2 cell damage induced by oxysterols. (2020) (14)
- Ethanol-induced effects on expression level, activity, and distribution of protein kinase C isoforms in rat liver Golgi apparatus. (1998) (14)
- In vitro evidence for CCl4 metabolites covalently bound to lipoprotein micelles (1983) (14)
- Comparative evaluation of the antioxidant activity of alpha-tocopherol, alpha-tocopherol polyethylene glycol 1000 succinate and alpha-tocopherol succinate in isolated hepatocytes and liver microsomal suspensions. (1990) (14)
- Acetaldehyde involvement in ethanol-induced potentiation of rat hepatocyte damage due to the carcinogen 1,2-dibromoethane. (1995) (13)
- Modulation of hepatic fibrogenesis by antioxidants. (1993) (13)
- Oxidized products of cholesterol: toxic effects. (2005) (13)
- Induction of cytochrome(s) P450‐dependent drug metabolism in cultured MH1C1 hepatoma cells (1984) (13)
- Studies on fatty liver with isolated hepatocytes. III. Cumene hydroperoxide-induced change of several cell functions. (1984) (13)
- Electron spin resonance studies on isolated hepatocytes treated with ferrous or ferric iron. (1987) (13)
- Molecular mechanisms of calorie restriction's protection against age‐related sclerosis (2006) (12)
- Effect of perioperative infusion of antioxidants on neutrophil activation during liver transplantation in humans. (2002) (12)
- Cytolysis does not per se induce lipid peroxidation: evidence in man. (1995) (12)
- Effect of industrial processing and storage procedures on oxysterols in milk and milk products. (2020) (11)
- Oxysterols: From redox bench to industry (2021) (11)
- Potential modulation of cancer progression by oxysterols. (2016) (11)
- Protective Effect of Cocoa Bean Shell against Intestinal Damage: An Example of Byproduct Valorization (2021) (11)
- Nitric Oxide Level Profile in Human Liver Transplantation (2002) (11)
- Tumor necrosis factor-alpha in airway secretions from cystic fibrosis patients upregulate endothelial adhesion molecules and induce airway epithelial cell apoptosis: implications for cystic fibrosis lung disease. (2008) (11)
- Contribution of gamma glutamyl transpeptidase to oxidative damage of ischemic rat kidney. (2000) (11)
- Inhibition of liver Golgi glycosylation activities by carbonyl products of lipid peroxidation. (1987) (11)
- Iron Overload: Experimental Approach Using Rat Hepatocytes in Single Cell Suspension (1986) (10)
- Editorial Introduction to the Special Issue on 4-Hydroxynonenal and Related Lipid Oxidation Products. (2017) (10)
- In vivo potentiation of 1,2-dibromoethane hepatotoxicity by ethanol through inactivation of glutathione-s-transferase. (1996) (10)
- Gas chromatography-mass spectrometry microanalysis of alpha- and gamma-tocopherol in plasma and whole blood. (2015) (10)
- Cholesterol and amyloid-beta: Evidence for a cross-talk between astrocytes and neuronal cells (2011) (10)
- Molecular Signaling Involved in Oxysterol-Induced β1-Integrin Over-Expression in Human Macrophages (2012) (10)
- Up‐regulation of COX‐2 and mPGES‐1 by 27‐hydroxycholesterol and 4‐hydroxynonenal: A crucial role in atherosclerotic plaque instability (2018) (10)
- Introduction--serial review: reactive oxygen and nitrogen in inflammation(1,2). (2002) (10)
- Metabolism of 4-hydroxynonenal in hepatoma cell lines. (1991) (9)
- Influence of lipid peroxidation on lipoprotein secretion by isolated hepatocytes (1981) (8)
- Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis. (2020) (8)
- The core‐aldehyde 9‐oxononanoyl cholesterol increases the level of transforming growth factor β1‐specific receptors on promonocytic U937 cell membranes (2009) (8)
- Evidence of an increased nitric oxide production in primary biliary cirrhosis. (2001) (8)
- Presence of cholesterol oxides in milk chocolates and their correlation with milk powder freshness (2022) (7)
- Modulation of cell signaling pathways by oxysterols in age-related human diseases. (2014) (7)
- TGFβ1 expression in colonic mucosa: modulation by dietary lipids (2007) (7)
- Relation between liver necrosis and intrahepatic cholestasis in rats poisoned with CCl4. (1987) (6)
- Effects of acute glutathione depletion induced by L-buthionine-(S,R)-sulfoximine on rat liver glucose-6-phosphatase activity. (1997) (6)
- Pro-hemolytic effect of aldehydic products of lipid peroxidation. (1987) (6)
- Carbon Tetrachloride-Induced Block of Hepatic Lipoprotein Secretion: Studies of the Pathogenesis Using Isolated Rat Hepatocytes (1984) (5)
- 4-Hydroxynonenal: a lipid degradation product provided with cell regulatory functions (2003) (5)
- Activation of human immunodeficiency virus long terminal repeat by arachidonic acid. (1997) (5)
- Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers (2021) (5)
- Oxysterols as Reliable Markers of Quality and Safety in Cholesterol Containing Food Ingredients and Products (2022) (5)
- Effect of aldehydes on polyamine metabolism. III. Inhibition of S-adenosyl methionine decarboxylase (SAMD) by CCl4 and by aldehydes produced during lipid peroxidation. (1981) (4)
- Analysis of the carbonyl compounds produced in beta thalassaemic erythrocytes by oxidative stress. (1989) (4)
- Free Radical Mediated Reactions and Ethanol Toxicity: Some Considerations on the Methodological Approaches (1991) (4)
- Ethanol-induced potentiation of rat hepatocyte damage due to 1,2-dibromoethane. (1995) (4)
- Change of liver metabolism of 1,2‐dibromoethane during simultaneous treatment with carbon tetrachloride (1993) (4)
- Effects of aldehyde products of lipid peroxidation on the activity of aldehyde metabolizing enzymes in hepatomas. (1993) (4)
- Early polyribosomal and lysosomal changes in the liver of rats poisoned with Amanita phalloides or phalloidin. (1975) (4)
- Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma (2020) (3)
- Role of 27-hydroxycholesterol and its metabolism in cancer progression: human studies. (2021) (3)
- The contribution of covalent binding and lipid peroxidation in the pathogenesis of fatty liver by CCl4 (1984) (3)
- 27-Hydroxycholesterol inhibits rhinovirus replication in vitro and on human nasal and bronchial histocultures without selecting viral resistant variants. (2022) (3)
- Lipid peroxidation and inflammatory molecules as markers of coronary artery disease (2007) (3)
- Reduction of oxidative stress in adjuvant arthritis. Effect of pyridoindole derivatives (2009) (3)
- Evidence for a Possible Role of Lipid Peroxidation in Experimental Liver Fibrosis (1993) (3)
- Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production (2022) (3)
- Cholesterol oxidation products and fibrogenesis (2001) (3)
- Age related changes of glucagon binding and activity in isolated rat hepatocytes. (1986) (2)
- High cholesterol diet, oxysterols and their impact on the gut–brain axis (2022) (2)
- Primary role of alcohol dehydrogenase pathway in acute ethanol-induced impairment of protein kinase C-dependent signaling system. (1999) (2)
- Lipid peroxidation and haloalkylation in CCl4-induced liver fatty degeneration and necrosis. (1988) (2)
- Studies on lipid peroxidation using whole liver cells: Influence of damaged cells on the prooxidant effect of ADP-Fe3+ and CCl4 (1981) (2)
- Cholesterol oxidation products induce spots of beta-amyloid aggregation on neuronal cells and may potentiate the peptide neurotoxic effects: A molecular link between hypercholesterolemia and Alzheimer's disease (2012) (2)
- Modulation of hepatic fibrogenesis by antioxidants (1995) (2)
- Studies on lipid peroxidation using isolated rat liver cells: the role of singlet oxygen in the propagation of lipid peroxidation ADP-Fe3+ or CCl4 induced. (1980) (2)
- P-10 - Role of 27-hydroxycholesterol and 4-hydroxynonenal in atherosclerotic plaque vulnerability (2016) (1)
- Neuron survival modulated by 24-hydroxycholesterol: the role of sirtuin pathway in Alzheimer's Disease. (2016) (1)
- Oxysterols are involved in colorectal carcinogenesis by damaging intestinal layer (2017) (1)
- Susceptibility and resistance of rat liver tissue to oxidative damage during diethylnitrosamine carcinogenesis (1985) (1)
- In Memoriam: Mario UmbertoDianzani’s scientific legacy. (2016) (1)
- The controversial role of 24S-hydroxycholesterol in Alzheimer's disease (2023) (1)
- Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways. (2012) (1)
- Reperfusion injury of the liver:protective effect of ischemic preconditioning. (2003) (1)
- The CCl4-Induced Increase of Free Arachidonate in Hepatocytes (1988) (1)
- 219 Angiotensin II type 1 receptor inhibition in early stage cirrhotic patients: Effects on portal pressure and liver fibrosis (2004) (1)
- Inactivation of hepatocyte protein kinase C by carbon tetrachloride: Involvement of drug's metabolic activation and prooxidant effect (1990) (1)
- Lipid Peroxidation and Irreversible Hepatocyte Damage (1988) (1)
- Special issue on "molecular mechanisms and new therapeutic targets in human carcinogenesis". (2010) (1)
- The silver lining of cerebrosterol in Alzheimer’s disease: the involvement of sirtuin 1 in neuroprotection. (2017) (1)
- Molecular Mechanism of Oxysterol Induced Survival Response: The Role of Autophagy and ROS (2016) (1)
- Catherine Pasquier award winner - Mitochondrial oxidative stress and apoptosis in liver disease (2005) (1)
- Interaction between 4-hydroxynonenal and amyloid-beta in amplifying neuronal damage (2012) (0)
- Redox Experimental Medicine: Linking redox research to human health and disease (2022) (0)
- A new biochemical effect of 4-hydroxynonenal: downregulation of TGFβ-dependent elastogenesis. (2014) (0)
- Rat hepatocytes in single cell suspension: A still suitable system for lipid peroxidation studies (2004) (0)
- Survival signals induced by low concentrations of 27-hydroxycholesterol in human monocytic cells via ERK activation (2012) (0)
- Oxidative stress and tissue damage after human liver transplantation (1995) (0)
- OXYSTEROLS INDUCE MACROPHAGE FOAM CELL FORMATION THROUGH PKC/ERK- DEPENDENT CD36 OVEREXPRESSION (2008) (0)
- Oxysterols: a likely molecular link between hypercholesterolemia & pathology (2009) (0)
- PO9-221 PRO-INFLAMMATORY EFFECT OF OXYSTEROLS: UP-REGULATION OF MCP-1 IN MACROPHAGE CELLS (2007) (0)
- Effect of leukocyte apheresis on oxidative stress and fibrosis in inflammatory bowel diseases (2008) (0)
- Short title: Inflammation and oxidative stress in CRC Full title: Inflammatory and redox reactions in colorectal carcinogenesis (0)
- Salicylate counteracts streptozotocin induced diabetes mellitus in rat (2002) (0)
- 252 Plaque Oxysterols Induce Imbalanced Up-Regulation of Mmp-9 in Macrophagic Cells Through Redox-Sensitive Signaling Pathways (2011) (0)
- Oxysterols along the course of Alzheimer’s disease. (2016) (0)
- Effect of methyl glyoxal on enzyme release and on protein synthesis and secretion by isolated hepatocytes. (1979) (0)
- Effects of lipid peroxidation carbonyl products on rat hepatocyte protein kinases (1989) (0)
- 4-Hydroxynonenal elicits in human hepatic stellate cells a c-jun/JNK2/AP-1 signalling pathway preceeded by early generation of nuclear adducts. (1997) (0)
- OXIDATIVE DAMAGE AND REPERFUSION SYNDROME IN HUMAN LIVER TRANSPLANTATION (1998) (0)
- Effect of packaging in preventing cholesterol autoxidation in milk chocolates for a higher quality and safer shelf-life (2023) (0)
- PO9-210 CHOLESTEROL OXIDATION PRODUCTS INDUCE FOAM CELL FORMATION THROUGH CD36 OVEREXPRESSION (2007) (0)
- Pro-inflammatory effect of oxysterol: up-regulation of MCP-1 in macrophage cells. (2007) (0)
- Ascorbate potentiates phorbol ester-induced nuclear binding of AP-1 in cells of macrophagic lineage. (2002) (0)
- Overexpression of the fibrogenic cytokine TGF beta 1 in macrophages as induced by various lipid oxidation products (2002) (0)
- Pharmacological preconditioning by adenosine A2A receptor activation attenuates proteolytic and oxidative mechanisms of reperfusion damage in rat liver. (2006) (0)
- HNE and TGF-β 1 expression in colon carcinogenesis (2007) (0)
- Lipid peroxidation in hepatoma cell lines and their sensitivity to 4-hydroxynonenal (2004) (0)
- Polyphenols from Sardinian red wine can modulate NOX1-dependent reactive oxygen species production in human enterocyte-like cells treated with a dietary mixture of oxysterols (2012) (0)
- Effect of aldehydes on polyamine metabolism. II. Methylglyoxal-induced changes in S-adenosylmethionine decarboxylase (SAMD) activity and RNA synthesis and degradation in isolated hepatocytes. (1981) (0)
- Determination of plasma and tissue distribution of 27-hydroxycholesterol after a single oral administration in a mouse model (2022) (0)
- Interaction between oxidized lipids and amyloid-β in amplifying neuronal damage in Alzheimer's disease (2012) (0)
- 4-Hydroxy-2,3-nonenal production and metabolism in cholestatic livers (1995) (0)
- HPLC analyses of the aldehydic patterns produced during lipid peroxidation. (1982) (0)
- Role of Bcl-2 family members in 4-hydroxynonenal (HNE) mediated apoptosis (2009) (0)
- Focus on the controversial Role of 24-hydroxycholesterol in Alzheimer's disease (2022) (0)
- PO9-205 TGF-BETA1 UP-REGULATION BY 9-OXONONANOYL CHOLESTEROL, A MAJOR CHOLESTERYL ESTER OXIDATION PRODUCT, IN U937 CELLS (2007) (0)
- Effect of an essential fatty acid deficient diet on dimethylnitrosamine demethylation and derangement of liver polyribosomes induced by this drug. (1979) (0)
- The colostomized patient:a psycological and psycopathological investigation (1985) (0)
- Oxysterols, metalloproteases and atherosclerotic plaque rupture (2017) (0)
- Oxidative Stress and Cell Damage Following Orthotopic Liver Transplantation. (1996) (0)
- Protective effect of calorie restriction on age-induced fibrosis (2009) (0)
- Oxysterols: a likely molecular link between hypercholesterolemia and pathology in humans (2011) (0)
- Editorial: lifestyle and therapeutics in the elderly. (2014) (0)
- Pancreatic-carcinoma-cell-derived pro-angiogenic factors can induce endothelial-cell differentiation of a subset of circulating CD34+ progenitors (2013) (0)
- Cholesterol oxidation between health and disease (2020) (0)
- Moderate hypotermia inhibits the ros-dependent cell damage and death during hepatic ischemia-reperfusion in rat. (2006) (0)
- Impact of Dietary Fats on Cardiovascular Disease with a Specific Focus on Omega-3 Fatty Acids (2022) (0)
- [Inhibitors of protein synthesis and hepatic steatosis: difference between cycloheximide, emetine and N-dimethylnitrosamine]. (1974) (0)
- Cholesterol Oxidation Products in the Initiation, Progression, and Fate of Atherosclerotic Lesions (2015) (0)
- Oxidative stress and disease: atherosclerosis (2007) (0)
- Calorie restriction protects against age-related myocardial fibrosclerosis in the rat. (2007) (0)
- [Model of isolated hepatocytes in the study of hepatic steatosis]. (1982) (0)
- Functional impairment of intact rat liver cells due to biological aldehydes. (1982) (0)
- Oxidized lipids in atherosclerotic plaque instability (2018) (0)
- Methotrexate-based combinatory therapy of adjuvant arthritis. Effect of coenzyme Q10 supplementation (2009) (0)
- Rat hepatocytes in single cell suspension: a still suitable system for lipid peroxidation studies. (1993) (0)
- Neutrophil elastase and nitric oxide (NO) during ischemia-reperfusion and their relationships with sICAM-1 and antioxidants (1998) (0)
- Editorial: Nurturing sustainable nutrition through innovations in food science and technology (2022) (0)
- Experimental liver cirrhosis induced by carbon tetrachloride: a role for lipid peroxidation. (1993) (0)
- Free radicals in liver injury : proceedings of the international meeting held in Turin, June 27-29, 1985 (1985) (0)
- Pro-fibrogenic and pro-apoptotic effects of oxisterols, oxidised derivatives of cholesterol. (2002) (0)
- Damaging effets of cholesterol oxidation products on intestinal epithelial cells (2009) (0)
- Promethazine inhibits theformation ofaldehydic products oflipid peroxidation butnotcovalent binding resulting fromtheexposure ofratliver fractions toCC14 (1989) (0)
- Ursodeoxycholic acid (2016) (0)
- Effect of 4-hydroxy-2,3-nonenal on transforming growth factor-β1 gene expression in a macrophage cell line. (1999) (0)
- The core-aldehyde 9-oxononanoyl cholesterol increases the level of tgfbeta1 specific receptors on promonocytic U937 cell membranes. (2009) (0)
- Role of oxysterols in the progression of atherosclerotic lesions. (2012) (0)
- OXIDATIVE DAMAGE AND FIBROSCLEROSIS IN VARIOUS TISSUES (1998) (0)
- EDITORIAL: LIFESTYLE AND THERAPEUTICS IN THE ELDERLY. (2014) (0)
- Carbon tetrachloride induced oxidative stress at the level of liver golgi apparatus effect on lipoprotein secretion (1990) (0)
- TGF-BETA1 SIGNALING IN HUMAN PROMONOCYTIC CELLS INDUCED BY 9-OXONONANOYL CHOLESTEROL, A MAJOR CHOLESTERYL ESTER OXIDATION PRODUCT (2008) (0)
- 29 The novel IL-8 inhibitor repertaxin reduces the neutrophil recruitment in the rat liver submitted to ischemia/reperfusion injury (2003) (0)
- Metabolism of carbonyl compounds in mh 1c 1 and htc cell lines (1986) (0)
- The novel IL-8 inhibitor Repertaxin reduces the neutrophil infiltration and the tissue damage in a rat experimental model of liver ischemia/reperfusion injury (2002) (0)
- Free Radical Mediated Liver Toxicity (1989) (0)
- Effect of aldehydes on polyamine metabolism. I. Method used to determine CO2 produced "in vitro" in enzymatic reactions: its application in evaluation of S-adenosylmethionine decarboxylase (SAMD) activity. (1981) (0)
- Markers of plaque vulnerability induced by oxidized lipids. (2016) (0)
- Potentiation of amyloid-β-peptide neurotoxicity by 4-hydroxynonenal and 24-hydroxycholesterol (2012) (0)
- Phalloidin poisoning of isolated hepatocytes: Inhibition of protein synthesis (1977) (0)
- Involvement of TLR4 activated by 27-hydroxycholesterol in atherosclerotic plaque vulnerability. (2014) (0)
- Neutrophil infiltration of human fatty liver graft during OLT (2000) (0)
- Role of Bcl-2 protein family members in 4-hydroxynonenal mediated apoptosis (2009) (0)
- Oxysterol-mediated signalling as a primary molecular link between hypercholesterolemia and disease (2009) (0)
- Cholesterol oxidation products in the progression of atherosclerosis (2010) (0)
- Lipid Peroxidation and Hepatocyte Damage in the Animal Model and in Human Patients (1992) (0)
- Trend of key markers of macrophage-derived inflammatory mediators during colorectal tumor progression (2012) (0)
- Ischemic preconditioning attenuates the damage by lipid peroxidation in the rat liver (2000) (0)
- Involvement of oxysterols in the pathogenesis of Alzheimer's disease. (2012) (0)
- 1247 HIGH CHOLESTEROL DIET INDUCES STEATOHEPATITIS IN RAT, AND IS ASSOCIATED WITH OXYSTEROL OVERPRODUCTION AND MITOCHONDRIAL-DEPENDENT UPREGULATED OXIDATIVE STRESS (2013) (0)
- Potentiation by 1,2-dibromoethane of lipid peroxidation and irreversible hepatocyte damage due to carbon tetrachloride (1990) (0)
- Involvement of oxysterols in atherosclerotic plaque instability (2012) (0)
- Alteration of redox equilibrium and fibrosis in rat aorta during aging: effect of caloric restriction. (2004) (0)
- Ursodeoxycholic acid protects liver mitochondria against oxidative stress in secondary biliary cirrhosis via up-regulation of gamma-glutamylcysteine synthetase (2003) (0)
- ' Università di Torino Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer (0)
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