Gökhan S. Hotamisligil
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Turkish physician
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Gökhan S. Hotamisligilbiology Degrees
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Gökhan S. Hotamisligilphilosophy Degrees
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Biology Philosophy
Gökhan S. Hotamisligil's Degrees
- Doctorate Medicine Hacettepe University
Why Is Gökhan S. Hotamisligil Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gökhan S. Hotamisligil is a Turkish-American physician scientist; James Stevens Simmons Chair of Genetics and Metabolism at Harvard T.H. Chan School of Public Health ; Director of the Sabri Ülker Center for Metabolic Research and associate member of Harvard-MIT Broad Institute, Harvard Stem Cell Institute and the Joslin Diabetes Center.
Gökhan S. Hotamisligil's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Inflammation and metabolic disorders (2006) (7557)
- Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. (1993) (7475)
- Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
- Inflammation, stress, and diabetes. (2005) (3975)
- Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. (1995) (3606)
- Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes (2004) (3559)
- A central role for JNK in obesity and insulin resistance (2002) (3235)
- Inflammatory mechanisms in obesity. (2011) (3060)
- IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance (1996) (2631)
- Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease (2010) (2461)
- Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes (2006) (2303)
- Protection from obesity-induced insulin resistance in mice lacking TNF-α function (1997) (2080)
- Obesity-induced inflammatory changes in adipose tissue. (2003) (1819)
- Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth (2011) (1638)
- Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets (2008) (1282)
- Inflammation, metaflammation and immunometabolic disorders (2017) (1247)
- Plasma adiponectin levels and risk of myocardial infarction in men. (2004) (1211)
- Tumor necrosis factor alpha inhibits signaling from the insulin receptor. (1994) (1186)
- Tumor Necrosis Factor α: A Key Component of the Obesity-Diabetes Link (1994) (1133)
- Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. (1997) (1100)
- Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. (2010) (1098)
- Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism (2008) (992)
- Nutrient sensing and inflammation in metabolic diseases (2008) (959)
- Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2, the Adipocyte Fatty Acid Binding Protein (1996) (884)
- Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity (2011) (832)
- Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. (1994) (829)
- Plasma Adiponectin Levels and Risk of Myocardial Infarction in Men (2004) (777)
- The role of TNFα and TNF receptors in obesity and insulin resistance (1999) (742)
- Deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice (2009) (718)
- Inflammatory pathways and insulin action (2003) (717)
- The interaction of hepatic lipid and glucose metabolism in liver diseases. (2012) (707)
- Novel role of PKR in inflammasome activation and HMGB1 release (2012) (679)
- Lack of macrophage fatty-acid–binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis (2001) (657)
- Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2 (2007) (636)
- Neuronal PTP1B regulates body weight, adiposity and leptin action (2006) (595)
- Habitual Dietary Intake of n-3 and n-6 Fatty Acids in Relation to Inflammatory Markers Among US Men and Women (2003) (577)
- Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease Published, JLR Papers in Press, May 9, 2007. (2007) (525)
- Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways. (2011) (511)
- Function of GATA transcription factors in preadipocyte-adipocyte transition. (2000) (494)
- SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice* (2001) (480)
- Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis (2010) (465)
- Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis (2009) (461)
- The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. (2012) (460)
- Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss (2009) (458)
- Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism (2017) (454)
- Mechanisms of TNF-alpha-induced insulin resistance. (2009) (443)
- Adipose Tissue Resistin Expression Is Severely Suppressed in Obesity and Stimulated by Peroxisome Proliferator-activated Receptor γ Agonists* (2001) (435)
- Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. (2008) (434)
- Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. (2005) (430)
- Tumor Necrosis Factor (TNF)-α Inhibits Insulin Signaling through Stimulation of the p55 TNF Receptor and Activation of Sphingomyelinase* (1996) (425)
- The role of TNF alpha in adipocyte metabolism. (1999) (419)
- Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. (1997) (414)
- Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes (2010) (396)
- Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling. (2006) (396)
- Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. (1994) (396)
- Metabolic functions of FABPs—mechanisms and therapeutic implications (2015) (379)
- Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. (2006) (362)
- Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women (2010) (354)
- Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. (2006) (347)
- Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. (2005) (342)
- Trans-Palmitoleic Acid, Metabolic Risk Factors, and New-Onset Diabetes in U.S. Adults (2010) (333)
- Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity (2014) (327)
- Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment (2016) (306)
- The Fatty Acid-binding Protein, aP2, Coordinates Macrophage Cholesterol Trafficking and Inflammatory Activity (2005) (300)
- Adipocyte stress: the endoplasmic reticulum and metabolic disease (2007) (298)
- Coordinated regulation of protein synthesis and degradation by mTORC1 (2014) (294)
- Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice. (2008) (285)
- Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes. (1993) (285)
- Molecular mechanisms of insulin resistance and the role of the adipocyte (2000) (278)
- Foundations of Immunometabolism and Implications for Metabolic Health and Disease. (2017) (275)
- Endoplasmic reticulum stress and atherosclerosis (2010) (273)
- Cell Signaling and Stress Responses. (2016) (270)
- Human monoamine oxidase A gene determines levels of enzyme activity. (1991) (268)
- Inflammation and endoplasmic reticulum stress in obesity and diabetes (2008) (264)
- A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease. (2006) (263)
- Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers. (2003) (253)
- Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses. (2004) (251)
- The role of TNFalpha and TNF receptors in obesity and insulin resistance. (1999) (249)
- The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue (2017) (248)
- Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. (1998) (247)
- Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes (2013) (246)
- Dual and opposing roles of the unfolded protein response regulated by IRE1α and XBP1 in proinsulin processing and insulin secretion (2011) (245)
- Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2. (2000) (234)
- Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation (2005) (233)
- Differential Regulation of the p80 Tumor Necrosis Factor Receptor in Human Obesity and Insulin Resistance (1997) (228)
- Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases (2010) (225)
- Through thick and thin: Wasting, obesity, and TNFα (1993) (224)
- trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). (2013) (223)
- Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes. (2015) (223)
- Tumor necrosis factor α is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1 (1999) (216)
- Coordinated Regulation of Nutrient and Inflammatory Responses by STAMP2 Is Essential for Metabolic Homeostasis (2007) (205)
- A prospective study of inflammatory cytokines and diabetes mellitus in a multiethnic cohort of postmenopausal women. (2007) (203)
- Role of the fatty acid binding protein mal1 in obesity and insulin resistance. (2003) (199)
- Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice. (1999) (194)
- Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production. (2013) (192)
- The role of fatty acid binding proteins in metabolic syndrome and atherosclerosis (2005) (185)
- FABP4 Attenuates PPARγ and Adipogenesis and Is Inversely Correlated With PPARγ in Adipose Tissues (2014) (183)
- Combined Adipocyte-Macrophage Fatty Acid–Binding Protein Deficiency Improves Metabolism, Atherosclerosis, and Survival in Apolipoprotein E–Deficient Mice (2004) (182)
- β-Adrenergic regulation of IL-6 release from adipose tissue: In vivo and in vitro studies (2001) (180)
- Circulating palmitoleic acid and risk of metabolic abnormalities and new-onset diabetes. (2010) (179)
- The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities. (2005) (178)
- Altered Tumor Necrosis Factor-α (TNF-α) Processing in Adipocytes and Increased Expression of Transmembrane TNF-α in Obesity (2002) (177)
- S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction (2015) (174)
- Adipocyte Fatty Acid–Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation in Severe Hypercholesterolemia (2002) (172)
- Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms (2015) (172)
- Association between dietary factors and plasma adiponectin concentrations in men. (2005) (163)
- Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. (2001) (155)
- Chronic enrichment of hepatic ER-mitochondria contact sites leads to calcium dependent mitochondrial dysfunction in obesity (2014) (155)
- CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. (2009) (151)
- Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year. (2003) (148)
- Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders (2012) (144)
- Transmembrane Tumor Necrosis Factor (TNF)-α Inhibits Adipocyte Differentiation by Selectively Activating TNF Receptor 1* (1999) (144)
- Circulating Levels of Endothelial Adhesion Molecules and Risk of Diabetes in an Ethnically Diverse Cohort of Women (2007) (144)
- The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation. (2006) (143)
- The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans (2019) (136)
- Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity (2018) (130)
- NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis (2017) (129)
- Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway (2012) (123)
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. (2006) (121)
- Tumor necrosis factor alpha mediates apoptosis of brown adipocytes and defective brown adipocyte function in obesity. (2000) (118)
- Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. (2003) (117)
- A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid utilization (2013) (115)
- beta-Adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies. (2001) (112)
- A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity (2008) (112)
- Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle. (2016) (111)
- Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity. (2002) (110)
- Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages. (2015) (106)
- Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity (2015) (104)
- The Role of JNK Proteins in Metabolism (2010) (98)
- Tumor necrosis factor alpha is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1. (1999) (95)
- Capillary Endothelial Fatty Acid Binding Proteins 4 and 5 Play a Critical Role in Fatty Acid Uptake in Heart and Skeletal Muscle (2013) (94)
- Potential role for snoRNAs in PKR activation during metabolic stress (2015) (89)
- Characterisation of receptor‐specific TNFα functions in adipocyte cell lines lacking type 1 and 2 TNF receptors (2000) (89)
- Exclusive Action of Transmembrane TNFα in Adipose Tissue Leads to Reduced Adipose Mass and Local But Not Systemic Insulin Resistance. (2002) (89)
- 12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat. (2019) (88)
- Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFα (2002) (87)
- Regulation of Metabolic Responses by Adipocyte/ Macrophage Fatty Acid–Binding Proteins in Leptin-Deficient Mice (2006) (86)
- Regulation of Dendritic Cell Function and T Cell Priming by the Fatty Acid-Binding Protein aP21 (2006) (85)
- Linking the inflammasome to obesity-related disease (2011) (85)
- Serum Fatty Acid-Binding Protein 4 Is a Predictor of Cardiovascular Events in End-Stage Renal Disease (2011) (84)
- Aberrant islet unfolded protein response in type 2 diabetes (2014) (82)
- Improved glucose and lipid metabolism in genetically obese mice lacking aP2. (2000) (81)
- Dietary and lifestyle factors in relation to plasma leptin concentrations among normal weight and overweight men (2001) (81)
- Hereditary variations in monoamine oxidase as a risk factor for Parkinson's disease (1994) (80)
- Perspectives in Diabetes Tumor Necrosis Factor a: A Key Component of the Obesity-Diabetes Link (1994) (79)
- Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity (2015) (78)
- Prevention of atherosclerosis by bioactive palmitoleate through suppression of organelle stress and inflammasome activation (2016) (77)
- Divergent androgen regulation of unfolded protein response pathways drives prostate cancer (2015) (74)
- Turning off the inflammatory, but not the metabolic, flames (2013) (73)
- Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals (2001) (73)
- Molecular Mechanisms of Adipocyte Differentiation (2001) (72)
- Metabolic Messengers: tumour necrosis factor (2021) (70)
- Adipokine FABP4 integrates energy stores and counterregulatory metabolic responses (2019) (70)
- Structure of the human gene for monoamine oxidase type A. (1991) (68)
- The role of adipocyte XBP1 in metabolic regulation during lactation. (2013) (67)
- Deficiency of Fatty Acid-Binding Proteins in Mice Confers Protection from Development of Experimental Autoimmune Encephalomyelitis1 (2007) (66)
- Plasma leptin concentrations and four-year weight gain among US men (2001) (65)
- Glycemic status and soluble tumor necrosis factor receptor levels in relation to plasma leptin concentrations among normal weight and overweight US men (2000) (64)
- The irresistible biology of resistin. (2003) (63)
- Role of Endoplasmic Reticulum Stress and c-Jun NH 2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes (2005) (63)
- Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes (2015) (62)
- Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma. (2013) (61)
- Functional Analysis of Tumor Necrosis Factor (TNF) Receptors in TNF-α-Mediated Insulin Resistance in Genetic Obesity* * This work is supported in part by a grant from the NIH (DK-52539). (1998) (55)
- Small-Molecule Inhibitors of PKR Improve Glucose Homeostasis in Obese Diabetic Mice (2014) (53)
- Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting (2012) (52)
- Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-&ggr;–Regulated Genes (2011) (51)
- Exclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistance. (2002) (50)
- A Critical Role of Fatty Acid Binding Protein 4 and 5 (FABP4/5) in the Systemic Response to Fasting (2013) (49)
- De Novo Lipogenesis Products and Endogenous Lipokines (2016) (46)
- A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity. (2015) (45)
- Effects of obesity and weight loss on the expression of proteins involved in fatty acid metabolism in human adipose tissue (2002) (43)
- Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. (2003) (42)
- Adipocyte/macrophage fatty acid binding proteins in metabolic syndrome (2007) (40)
- The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB (2020) (39)
- Signaling pathways utilized by tumor necrosis factor receptor 1 in adipocytes to suppress differentiation (2001) (37)
- Stamp2 controls macrophage inflammation through nicotinamide adenine dinucleotide phosphate homeostasis and protects against atherosclerosis. (2012) (37)
- Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity (2017) (36)
- GATA transcription factors and fat cell formation. (2003) (35)
- Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses (2015) (35)
- The transcription factor GATA2 regulates differentiation of brown adipocytes (2005) (35)
- Relationship Between Platelet Monoamine Oxidase B Activity and Alleles at the MAOB Locus (1992) (34)
- Adipocytes promote interleukin-18 binding to its receptors during abdominal aortic aneurysm formation in mice. (2019) (34)
- Interaction of Tumor Necrosis Factor-α- and Thiazolidinedione-Regulated Pathways in Obesity (2004) (32)
- Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism. (2020) (31)
- Metabolism: Host and microbes in a pickle (2010) (31)
- Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice (2016) (31)
- Functional RNA Interference (RNAi) Screen Identifies System A Neutral Amino Acid Transporter 2 (SNAT2) as a Mediator of Arsenic-induced Endoplasmic Reticulum Stress* (2012) (30)
- Stressing the Brain, Fattening the Body (2008) (30)
- Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes. (2007) (30)
- The role of TNFa in adipocyte metabolism (1999) (30)
- Upregulation of uncoupling protein 2 mRNA in genetic obesity: lack of an essential role for leptin, hyperphagia, increased tissue lipid content, and TNF-alpha. (2000) (30)
- Impact of ER Protein Homeostasis on Metabolism (2013) (26)
- The Proteus syndrome: association with nephrogenic diabetes insipidus (1990) (26)
- Autoamplification of Tumor Necrosis Factor-α : A Potential Mechanism for the Maintenance of Elevated Tumor Necrosis Factor-α in Male but Not Female Obese Mice (2006) (25)
- Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins. (2017) (25)
- The Fatty Acid-binding Protein, aP2, Coordinates Macrophage Cholesterol Trafficking and Inflammatory Activity: MACROPHAGE EXPRESSION OF aP2 IMPACTS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ AND I κ B KINASE ACTIVITIES* (2012) (23)
- Regulation of adiponectin in adipocytes upon exposure to HIV‐1 (2006) (22)
- JNK1 deficiency does not enhance muscle glucose metabolism in lean mice. (2006) (20)
- Regulation of liver subcellular architecture controls metabolic homeostasis (2022) (20)
- Fatty Acid Binding Protein 4 Deficiency Protects against Oxygen-Induced Retinopathy in Mice (2014) (20)
- The molecular link between obesity and diabetes (1996) (19)
- Developmental biology: Cell fate in the mammary gland (2007) (17)
- A hormone complex of FABP4 and nucleoside kinases regulates islet function (2021) (17)
- Damned if you do, damned if you don't: the conundrum of adipose tissue vascularization. (2013) (17)
- Interaction of tumor necrosis factor-alpha- and thiazolidinedione-regulated pathways in obesity. (2004) (16)
- Stability of human plasma leptin concentrations within 36 hours following specimen collection. (1999) (15)
- Autoamplification of tumor necrosis factor-alpha: a potential mechanism for the maintenance of elevated tumor necrosis factor-alpha in male but not female obese mice. (2006) (13)
- ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity. (2017) (13)
- Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H2O2 production in heart and skeletal muscle mitochondria (2020) (12)
- TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis (2018) (12)
- Endothelial cell-fatty acid binding protein 4 promotes angiogenesis: role of stem cell factor/c-kit pathway (2012) (12)
- Promoting atherosclerosis in type 1 diabetes through the selective activation of arachidonic acid and PGE(2) production. (2012) (9)
- High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism (2020) (7)
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis (DOI:10.1016/j.cmet.2006.02.010) (2006) (7)
- Immune Cell Intolerance for Excess Cholesterol. (2016) (6)
- Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue (2017) (5)
- CXCL 5 is an adipose tissue derived factor that links obesity to insulin resistance (2009) (4)
- TMEM2 Modulates ER Stress in a Non-canonical Manner. (2019) (4)
- Proteus syndrome and neurofibromatosis. (1989) (4)
- Aberrant Ca2+ homeostasis in adipocytes links inflammation to metabolic dysregulation in obesity (2020) (4)
- Type I Interferons Interfere with Liver Glucose Metabolism. (2017) (3)
- Feyza Engin Protects Mice Against Type 1 Diabetes Cells β Restoration of the Unfolded Protein Response in Pancreatic (2013) (3)
- Aberrant Ca2+ signaling by IP3Rs in adipocytes links inflammation to metabolic dysregulation in obesity (2021) (2)
- Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism. (2021) (2)
- Abstract 5045: Muscle-Type Capillary Endothelial Cells Actively Transport Fatty Acids via Intracellular Fatty Acid Binding Protein-4 and -5 (2009) (1)
- Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action (2010) (1)
- Adiponectin and Risk of Coronary Heart Disease—Reply (2004) (1)
- 055 Tissue resident memory T cell survival requires exogenous lipid uptake and metabolism (2017) (1)
- Supporting Information Notch Ligand Delta-like 4 Blockade Attenuates Atherosclerosis and Metabolic Disorders (2012) (1)
- OR01-1 Leveraging Immunometabolic Control to Prevent and Treat Obesity Related Asthma (2019) (1)
- Association between dietary factors and plasma adiponectin concentrations in men 1 – 3 (2005) (1)
- Regulation Expression Syndromes of Adipocyte Gene in Differentiation and of Obesity / Diabetes * (2001) (1)
- Plasma leptin and soluble TNF-receptors levels in relation to atherogenic and thrombogenic CVD risk factors among us men (2000) (1)
- Adiponectin and risk of coronary heart disease [2] (multiple letters) (2004) (0)
- An unexpected lack of difference in superoxide/H2O2 production rates in isolated heart and skeletal muscle mitochondria from a mouse model of Barth Syndrome (2020) (0)
- Command centers for metabolic control can be in the most unexpected places (2002) (0)
- Protection fromobesity-induced insulin resistance inmice lackingTNF-a function (1997) (0)
- Next‐generation nutritional screening (2017) (0)
- Long-Term Calorie Restric tion Enhances Cellular Quality-Control Processes in HumanSkeletalMuscle Graphical (2016) (0)
- PKR is required for NLRP3 inflammasome activation and HMGB1 release (114.7) (2012) (0)
- Fatty Acid Binding Protein 4‐deficient Mice are Protected from Oxygen‐induced Retinal Neovascularization (2011) (0)
- of Experimental Autoimmune Mice Confers Protection from Development Deficiency of Fatty Acid-Binding Proteins in (2017) (0)
- Regulation of liver subcellular architecture controls metabolic homeostasis (2022) (0)
- Small molecule inhibitors of PKR improve glucose homeostasis in obese (2013) (0)
- The RAGE Axis: A Fundamental Mechanism Signaling Danger to the Vulnerable Vasculature [2010;106:842–853] The Promise of Cell-Based Therapies for Diabetic Complications: Challenges and Solutions [2010;106:854–869] Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications [2010; (2010) (0)
- Time to Look Back and to Look Forward (2014) (0)
- Hepatic IRE1 Protects Against Septic Cardiac Failure (2023) (0)
- 053 Lipid scavenger molecule CD36 regulates free fatty acid uptake and peripheral maintenance of tissue resident memory T cells (2018) (0)
- Correction: A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity (2009) (0)
- Dual role of fatty acid-binding protein 5 on endothelial cell fate: a potential link between lipid metabolism and angiogenic responses (2015) (0)
- Compositions comprising an aP2-specific antibody or fragment thereof for use in the treatment of diabetes, glucose intolerance or insulin resistance induced by obesity (2010) (0)
- Abstract 15992: STAMP2 Controls Macrophage Inflammatory Responses by NADPH Regulation (2011) (0)
- Endoplasmic Reticulum Stress is Reduced in Tissues of Obese Subjects after Weight Loss Short running title : ER Stress is Reduced by Weight Loss in Obesity (2019) (0)
- Endothelial FABP4 constitutes the majority of basal circulating hormone levels and regulates lipolysis-driven insulin secretion (2022) (0)
- Reduction du stress du re dans le traitement de l'obesite et du diabete (2005) (0)
- Chapter 9 GATA proteins as molecular gatekeepers of adipogenesis (2006) (0)
- Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action (2010) (0)
- Abstract 19047: The Six-Transmembrane Protein STAMP2 Regulates Macrophage Inflammatory Responses and Protects From Atherosclerosis (2010) (0)
- Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation (2022) (0)
- Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity (2023) (0)
- Keynote Lecture : Molecular Mechanisms of Metabolic Syndrome (2003) (0)
- James R. Mitchell (1971-2020). (2021) (0)
- Encephalomyelitis of Experimental Autoimmune Mice Confers Protection from Development Deficiency of Fatty Acid-Binding Proteins in Suttles Gorgun (2007) (0)
- Impact of ER Protein Homeostasis on Metabolism this access benefits you. Your story matters (2013) (0)
- Erratum: Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis (2010) (0)
- Inflammatory Causes of Obesity and Metabolic Diseases (2014) (0)
- Role Of Fatty Acid Binding Protein 4 In Pulmonary Angiogenesis (2010) (0)
- Acid Uptake in Heart and Skeletal Muscle Capillary Endothelial Fatty Acid Binding Proteins 4 and 5 Play a Critical Role in Fatty (2013) (0)
- Chlamydia pneumoniae Lung Infection in Mice Induces Fatty Acid-Binding Protein 4-Dependent White Adipose Tissue Pathology. (2023) (0)
- nucleic acids inhibit the formation of atherosclerotic sore by AFABP antisense (2000) (0)
- ATGL is differentially required for adipocyte FABP4 secretion in vivo and ex vivo (2022) (0)
- Cell Priming by the Fatty Acid-Binding Regulation of Dendritic Cell Function and T (2006) (0)
- The role of Lipid Chaperones in Integrating Lipid Signals with Inflammatory and Metabolic Responses (2008) (0)
- 495 Divergent androgen regulation of UPR pathways drives prostate cancer (2014) (0)
- O-47: Mechanisms of TNF-α induced insulin resistance (2009) (0)
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