Gordon M. Crippen

Gordon M. Crippen's AcademicInfluence.com Rankings

Gordon M. Crippen

Chemistry

#4375

World Rank

#5452

Historical Rank

Physical Chemistry

#659

World Rank

#712

Historical Rank

chemistry Degrees

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Chemistry

Gordon M. Crippen's Degrees

PhD Chemistry University of California, Berkeley
Bachelors Chemistry University of California, Berkeley

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Gordon M. Crippen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Distance Geometry and Molecular Conformation (1988) (786)
Prediction of Physicochemical Parameters by Atomic Contributions (1999) (783)
Atomic physicochemical parameters for three-dimensional-structure-directed quantitative structure-activity relationships. 2. Modeling dispersive and hydrophobic interactions (1987) (630)
Atomic Physicochemical Parameters for Three‐Dimensional Structure‐Directed Quantitative Structure‐Activity Relationships I. Partition Coefficients as a Measure of Hydrophobicity (1986) (553)
Atomic physicochemical parameters for three dimensional structure directed quantitative structure‐activity relationships III: Modeling hydrophobic interactions (1988) (470)
The theory and practice of distance geometry (1983) (355)
Significance of root-mean-square deviation in comparing three-dimensional structures of globular proteins. (1994) (340)
Contact potential that recognizes the correct folding of globular proteins. (1992) (336)
A novel approach to calculation of conformation: Distance geometry (1977) (161)
Stable calculation of coordinates from distance information (1978) (156)
Effects of distance constraints on macromolecular conformation. II. Simulation of experimental results and theoretical predictions (1979) (149)
The tree structural organization of proteins. (1978) (136)
Calculation of protein tertiary structure. (1976) (122)
Size‐independent comparison of protein three‐dimensional structures (1995) (122)
A combinatorial algorithm for calculating ligand binding (1984) (115)
Prediction of protein folding from amino acid sequence over discrete conformation spaces. (1991) (108)
Distance geometry and conformational calculations (1981) (104)
Prediction of Physicochemical Parameters by Atomic Contributions. (1999) (100)
Minimization of polypeptide energy. XI. The method of gentlest ascent. (1971) (80)
Distance geometry approach to rationalizing binding data. (1979) (80)
Predicting p K a . (2009) (72)
Purely in silico BCS classification: science based quality standards for the world's drugs. (2013) (66)
The combinatorial distance geometry method for the calculation of molecular conformation. I. A new approach to an old problem. (1983) (65)
Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors. (1985) (65)
Predicting pKa (2009) (64)
Note rapid calculation of coordinates from distance matrices (1978) (62)
Combined use of stereospecific deuteration, NMR, distance geometry, and energy minimization for the conformational analysis of the highly .delta. opioid receptor selective peptide [D-Pen2,D-Pen5]enkephalin (1990) (54)
Fast drug-receptor mapping by site-directed distances: a novel method of predicting new pharmacological leads (1991) (53)
A 1.8 Å resolution potential function for protein folding (1990) (52)
Exploring the conformation space of cycloalkanes by linearized embedding (1992) (46)
Minimization of polypeptide energy. X. A global search algorithm. (1971) (46)
Conformational analysis by energy embedding (1982) (46)
SAGA: rapid automatic mainchain NMR assignment for large proteins (2010) (42)
Linked and threaded loops in proteins (1980) (42)
Use of Classification Regression Tree in Predicting Oral Absorption in Humans (2004) (39)
Distance geometry analysis of the benzodiazepine binding site. (1982) (39)
Modeling the benzodiazepine receptor binding site by the general three-dimensional structure-directed quantitative structure-activity relationship method REMOTEDISC. (1990) (38)
Analysis of the in vitro antiviral activity of certain ribonucleosides against parainfluenza virus using a novel computer aided receptor modeling procedure. (1989) (38)
Quantitative structure-activity relationships by distance geometry: systematic analysis of dihydrofolate reductase inhibitors. (1980) (37)
Easily searched protein folding potentials. (1996) (34)
Learning about protein folding via potential functions (1994) (34)
pKa Prediction of Monoprotic Small Molecules the SMARTS Way (2008) (33)
Why energy embedding works (1987) (32)
A potential function for protein folding (1991) (32)
Global energy minimization by rotational energy embedding (1990) (32)
The combinatorial distance geometry method for the calculation of molecular conformation. II. Sample problems and computational statistics. (1983) (31)
Minimization of polypeptide energy. 8. Application of the deflation technique to a dipeptide. (1969) (31)
Data Mining the NCI60 to Predict Generalized Cytotoxicity (2008) (30)
How many protein folding motifs are there? (1995) (30)
Disulfide recognition in an optimized threading potential. (2000) (28)
General distance geometry three-dimensional receptor model for diverse dihydrofolate reductase inhibitors. (1984) (27)
Quantitative structure-activity relationship by distance geometry: quinazolines as dihydrofolate reductase inhibitors. (1982) (27)
Chemical Data Mining of the NCI Human Tumor Cell Line Database (2007) (26)
Residue-residue potential function for conformational analysis of proteins (1981) (25)
A Cheminformatic Toolkit for Mining Biomedical Knowledge (2007) (25)
Chemical distance geometry: Current realization and future projection (1991) (25)
Topology of globular proteins. II. (1975) (24)
Sidechain and backbone potential function for conformational analysis of proteins. (2009) (21)
Correlation of sequence and tertiary structure in globular proteins (1977) (20)
Topology of globular proteins. (1974) (19)
Distance geometry analysis of the N.M.R. evidence on the solution conformation of bleomycin. (2009) (19)
Voronoi binding site models (1987) (19)
Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL. (2004) (18)
Conformational analysis by scaled energy embedding (1984) (18)
Three-dimensional molecular descriptors and a novel QSAR method. (2002) (18)
A survey of atom packing in globular proteins. (2009) (17)
Global optimization and polypeptide conformation (1975) (16)
Enumeration of cubic lattice walks by contact class (2000) (16)
CASA: An Efficient Automated Assignment of Protein Mainchain NMR Data Using an Ordered Tree Search Algorithm (2005) (15)
Failures of inverse folding and threading with gapped alignment (1996) (15)
Voronoi binding site model of a polycyclic aromatic hydrocarbon binding protein. (1990) (15)
Quantitative structure-activity relationships by distance geometry: thyroxine binding site. (1981) (15)
Objective models for steroid binding sites of human globulins (1997) (15)
Chirality Descriptors in QSAR (2008) (15)
A potential function for conformational analysis of proteins. (2009) (14)
Voronoi modeling: the binding of triazines and pyrimidines to L. casei dihydrofolate reductase. (1993) (14)
Energy embedding of trypsin inhibitor (1982) (14)
Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines. (1983) (14)
Voronoi binding site models: Calculation of binding modes and influence of drug binding data accuracy (1989) (13)
Validation of DAPPER for 3D QSAR: Conformational Search and Chirality Metric (2003) (13)
Distance constraints on macromolecular conformation. (2009) (13)
Analysis of cocaine receptor site ligand binding by three-dimensional Voronoi site modeling approach. (1993) (12)
Evaluation of Ligand Overlap by Atomic Parameters (2001) (12)
VRI: 3D QSAR at variable resolution (1999) (12)
A protein folding potential that places the native states of a large number of proteins near a local minimum (2002) (11)
Conformational sampling by a general linearized embedding algorithm (1992) (10)
The measurement of molecular diversity by receptor site interaction simulation (1998) (10)
Conformation of N-acetyl-L-alanine-N'-methylamide in 1,2-dichloroethane by circular dichroism and optical rotatory dispersion (1974) (9)
Potential Energy Function for Continuous State Models of Globular Proteins (2000) (9)
Lattice models of protein folding permitting disordered native states (2002) (9)
A computer model for the 30S ribosome subunit. (1980) (9)
An alternative approach to distance geometry using L∞ distances (2015) (8)
Molecular orbital study of the ring nitrogen basicity of various dihydrofolate reductase inhibitors (1985) (7)
Intervals and the deduction of drug binding site models (1995) (7)
Minimization of polypeptide energy XII. The methods of partial energies and cubic subdivision (1973) (7)
A Gaussian statistical mechanical model for the equilibrium thermodynamics of barnase folding. (2001) (7)
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data. (1997) (7)
Failures of inverse folding and threading with gapped alignment. (1996) (7)
Protein densities. (1979) (6)
Deduction of Binding Site Structure from Ligand Binding Data (1985) (6)
Constructing smooth potential functions for protein folding. (2001) (6)
Use of Classification Regression Tree in Predicting Oral Absorption in Humans. (2005) (6)
Data Mining the NCI60 to Predict Generalized Cytotoxicity. (2008) (6)
Deducing molecular similarity using Voronoi binding sites (1993) (5)
Recognizing protein folds by cluster distance geometry (2005) (5)
Cluster distance geometry of polypeptide chains (2004) (5)
Series approximation of protein structure and constructing conformation space (2003) (5)
A statistical approach to the calculation of conformation of proteins. 1. Theory. (1977) (5)
DISTANCE GEOMETRY APPROACH TO RATIONALIZING BINDING DATA (1980) (5)
Chemical Data Mining of the NCI Human Tumor Cell Line Database. (2008) (5)
A statistical approach to the calculation of conformation of proteins. 2. The reoxidation of reduced trypsin inhibitor. (1977) (5)
Contact Potential for Global Identification of Correct Protein Folding (1994) (5)
Statistical mechanics of protein folding by cluster distance geometry (2004) (5)
Prediction of New Leads from a Distance Geometry Binding Site Model (1983) (4)
Dimensional oscillation. A fast variation of energy embedding gives good results with the AMBER potential energy function. (2009) (4)
An iterative refinement algorithm for consistency based multiple structural alignment methods (2006) (4)
Statistical mechanics of protein folding with separable energy functions (2004) (4)
Directional structural features of globular proteins. (1977) (3)
Distance Geometry for Realistic Molecular Conformations (2013) (3)
Fold Recognition via a Tree (2006) (2)
Protein folding and fold recognition for square lattice models. (1997) (2)
Why are binding-site models more complicated than molecules? (1993) (2)
Fast Drug‐Receptor Mapping by Site‐Directed Distances: A Novel Method of Predicting New Pharmacological Leads. (1991) (1)
USE OF PHYSICOCHEMICAL PARAMETERS IN DISTANCE GEOMETRY AND RELATED THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS: A DEMONSTRATION USING ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE INHIBITORS (1985) (1)
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP BY DISTANCE GEOMETRY: QUINAZOLINES AS DIHYDROFOLATE REDUCTASE INHIBITORS (1983) (1)
Toward Correct Protein Folding Potentials (2004) (1)
Determining contact energy function for continuous state models of globular protein conformations (2000) (1)
QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS BY DISTANCE GEOMETRY: THYROXINE BINDING SITE (1981) (1)
COMBINED DISTANCE GEOMETRY ANALYSIS OF DIHYDROFOLATE REDUCTASE INHIBITION BY QUINAZOLINES AND TRIAZINES (1983) (0)
Cluster Distance Geometry and Protein Folding (2006) (0)
CONFORMATION OF N-ACETYL-L-ALANINE-N′-METHYLAMIDE IN 1,2-DICHLOROETHANE BY CIRCULAR DICHROISM AND OPTICAL ROTATORY DISPERSION (1974) (0)
(Probably) all possible protein folds at low resolution. (1996) (0)
Protein folding potential functions (1995) (0)
Deducing Objective Site Models by Mixed Integer Programming (1999) (0)
A GENERAL DISTANCE-GEOMETRY THREE-DIMENSIONAL RECEPTOR MODEL FOR DIVERSE DIHYDROFOLATE REDUCTASE INHIBITORS (1984) (0)
Reviews in Computational Chemistry, Volume 32 (2022) (0)
How to describe chirality and conformational flexibility. (2004) (0)
ISCB/SPRINGER series in computational biology (2014) (0)
A solvation potential with improved contact definitions and optimized by extensive threading (1999) (0)
Distance geometry vs . coordinates for protein folding calculations (2007) (0)
A statistical measure of association and a series expansion of chain conformations (2009) (0)
Panel Discussion: New Problems that Should be Addressed in the Next Ten Years (1999) (0)
Conformational Analysis: Homotopy (2002) (0)

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What Schools Are Affiliated With Gordon M. Crippen?

Gordon M. Crippen is affiliated with the following schools:

University of Michigan