Graciela Andrei

Q: What Schools Are Affiliated With Graciela Andrei

Graciela Andrei is affiliated with the following schools: University of California, Berkeley, KU Leuven, Cardiff University, Stanford University

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Graciela Andrei

Computer Science

#9157

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#9622

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Computational Linguistics

#2168

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#2190

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Machine Learning

#3943

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#3991

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Artificial Intelligence

#4273

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#4333

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computer-science Degrees

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Computer Science

Graciela Andrei's Degrees

PhD Computer Science Stanford University
Masters Computer Science University of California, Berkeley
Bachelors Computer Science University of California, Berkeley

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Graciela Andrei's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Synthesis and antiviral activity of new pyrazole and thiazole derivatives. (2009) (281)
Activities of various compounds against murine and primate polyomaviruses (1997) (236)
HPMPC (cidofovir), PMEA (adefovir) and Related Acyclic Nucleoside Phosphonate Analogues: A Review of their Pharmacology and Clinical Potential in the Treatment of Viral Infections (1997) (234)
Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma (2018) (233)
Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain. (2000) (176)
Synthesis and antiviral activity of imidazo[1,2-a]pyridines (1999) (170)
Synthesis of imidazo[1,2-a]pyridines as antiviral agents. (1998) (165)
Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base. (1999) (164)
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). (1994) (149)
Antiadenovirus Activities of Several Classes of Nucleoside and Nucleotide Analogues (2005) (148)
Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. (1999) (146)
The Novel Immunosuppressive Agent Mycophenolate Mofetil Markedly Potentiates the Antiherpesvirus Activities of Acyclovir, Ganciclovir, and Penciclovir In Vitro and In Vivo (1998) (133)
Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents. (1996) (132)
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity. (2002) (130)
Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication. (2011) (127)
Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds (1991) (122)
Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents. (2010) (115)
The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications (2013) (114)
Activity of a Sulfated Polysaccharide Extracted from the Red Seaweed Aghardhiella Tenera against Human Immunodeficiency Virus and Other Enveloped Viruses (1994) (110)
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides. (1995) (97)
Treatment of anogenital papillomavirus infections with an acyclic nucleoside phosphonate analogue. (1995) (95)
5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity. (2003) (93)
Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata. (1994) (93)
Molecular approaches for the treatment of hemorrhagic fever virus infections. (1993) (93)
Induction of apoptosis by cidofovir in human papillomavirus (HPV)-positive cells. (2001) (93)
Antivaccinia Activities of Acyclic Nucleoside Phosphonate Derivatives in Epithelial Cells and Organotypic Cultures (2002) (91)
Iron chelators inhibit the growth and induce the apoptosis of Kaposi's sarcoma cells and of their putative endothelial precursors. (2000) (91)
Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines. (1998) (91)
Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro. (1990) (91)
Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II. (2007) (90)
Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design. (1992) (88)
Cidofovir Activity against Poxvirus Infections (2010) (88)
Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2. (1996) (85)
Drug targets in cytomegalovirus infection. (2009) (83)
Antiviral enantiomeric preference for 5'-noraristeromycin. (1994) (81)
Sulphated Polymers are Potent and Selective Inhibitors of Various Enveloped Viruses, Including Herpes Simplex Virus, Cytomegalovirus, Vesicular Stomatitis Virus, Respiratory Syncytial Virus, and Toga-, Arena- and Retroviruses (1990) (78)
Herpes simplex virus drug-resistance: new mutations and insights. (2013) (75)
Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423. (2004) (75)
Susceptibilities of Several Clinical Varicella-Zoster Virus (VZV) Isolates and Drug-Resistant VZV Strains to Bicyclic Furano Pyrimidine Nucleosides (2005) (74)
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus. (2007) (74)
Cidofovir Resistance in Vaccinia Virus Is Linked to Diminished Virulencein Mice (2006) (72)
Antitumor potential of acyclic nucleoside phosphonates. (1999) (71)
Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis (2016) (71)
CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor. (2002) (71)
Activity of the Anti-Orthopoxvirus Compound ST-246 against Vaccinia, Cowpox and Camelpox Viruses in Cell Monolayers and Organotypic Raft Cultures (2007) (71)
ANTIVIRAL POTENTIAL OF A NEW GENERATION OF ACYCLIC NUCLEOSIDE PHOSPHONATES, THE 6-[2-(PHOSPHONOMETHOXY)ALKOXY]-2,4-DIAMINOPYRIMIDINES (2005) (70)
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine. (2000) (69)
Acyclic nucleotide analogs derived from 8-azapurines: synthesis and antiviral activity. (1996) (66)
Antiproliferative and apoptotic effects of iron chelators on human cervical carcinoma cells. (2002) (65)
New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents. (1992) (65)
Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene. (2000) (64)
Vaccinia Virus–Encoded Ribonucleotide Reductase Subunits Are Differentially Required for Replication and Pathogenesis (2010) (64)
Synthesis and antiviral activity of 3-substituted imidazo[1,2-a]pyridines. (1994) (64)
Meningoradiculoneuritis due to acyclovir‐resistant varicella zoster virus in an acquired immune deficiency syndrome patient (1994) (64)
Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds. (2004) (63)
How Viruses Contribute to the Pathogenesis of Hemophagocytic Lymphohistiocytosis (2017) (62)
ACYCLIC/CARBOCYCLIC GUANOSINE ANALOGUES AS ANTI-HERPESVIRUS AGENTS (2001) (60)
Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides. (2005) (60)
Novel inhibitors of human CMV. (2008) (59)
Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues (2008) (57)
Antiviral Activity of Triazine Analogues of 1-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine (Cidofovir) and Related Compounds (2007) (56)
Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide. (2009) (55)
Novel Therapeutics for Epstein–Barr Virus (2019) (55)
The large tumor antigen: a "Swiss Army knife" protein possessing the functions required for the polyomavirus life cycle. (2013) (53)
Antiviral Activity of low-MW Dextran Sulphate (Derived from dextran MW 1000) Compared to Dextran Sulphate Samples of Higher MW (1991) (52)
New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. (2002) (51)
A new topical treatment for resistant herpes simplex infections. (1993) (51)
Cidofovir in the treatment of HPV-associated lesions. (2001) (50)
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation. (2011) (50)
Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity. (2007) (50)
Anti-influenza virus activity and structure–activity relationship of aglycoristocetin derivatives with cyclobutenedione carrying hydrophobic chains (2009) (50)
Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism. (2004) (50)
Characterization of Herpes Simplex Virus Type 1 Thymidine Kinase Mutants Selected under a Single Round of High-Dose Brivudin (2005) (50)
Cell-dependent interference of a series of new 6-aminoquinolone derivatives with viral (HIV/CMV) transactivation. (2005) (49)
The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications (2015) (49)
Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine. (2004) (48)
Broad-Spectrum Antiviral Activity and Mechanism of Antiviral Action of the Fluoroquinolone Derivative K-12 (1998) (48)
Iron as a potential co‐factor in the pathogenesis of Kaposi's sarcoma? (1998) (47)
Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus. (2002) (47)
Activities of Several Classes of Acyclic Nucleoside Phosphonates against Camelpox Virus Replication in Different Cell Culture Models (2007) (47)
Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission. (1998) (47)
Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid with biological activities. (2014) (47)
ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping (2015) (47)
Synthesis and antiviral/antitumor evaluation of 2-amino- and 2-carboxamido-3-arylsulfonylthiophenes and related compounds as a new class of diarylsulfones. (2001) (46)
Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus (1995) (46)
Differential antiviral activity of derivatized dextrans. (1995) (46)
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice. (1998) (45)
Organotypic Epithelial Raft Cultures as a Model for Evaluating Compounds against Alphaherpesviruses (2005) (45)
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells. (2007) (45)
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates. (2011) (44)
KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication (2014) (44)
Potent inhibition of hemangioma formation in rats by the acyclic nucleoside phosphonate analogue cidofovir. (1998) (44)
DNA Polymerase Mutations in Drug-Resistant Herpes Simplex Virus Mutants Determine In Vivo Neurovirulence and Drug-Enzyme Interactions (2007) (44)
Mouse Cytomegalovirus Infection in BALB/c Mice Resembles Virus-Associated Secondary Hemophagocytic Lymphohistiocytosis and Shows a Pathogenesis Distinct from Primary Hemophagocytic Lymphohistiocytosis (2016) (43)
Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer (1997) (43)
The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication (1994) (43)
Three-dimensional culture models for human viral diseases and antiviral drug development. (2006) (41)
2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections. (2002) (40)
Camelpox virus. (2011) (40)
Inhibitory activity of S-adenosylhomocysteine hydrolase inhibitors against human cytomegalovirus replication. (1993) (40)
Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives. (2006) (39)
Heterogeneity and evolution of thymidine kinase and DNA polymerase mutants of herpes simplex virus type 1: implications for antiviral therapy. (2013) (39)
Antiviral Drugs for EBV (2018) (38)
New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A. (1996) (38)
In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA. (2007) (38)
Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation. (2018) (38)
From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors. (2005) (38)
3-deaza- and 7-deaza-5'-noraristeromycin and their antiviral properties. (1995) (38)
GS-9191 Is a Novel Topical Prodrug of the Nucleotide Analog 9-(2-Phosphonylmethoxyethyl)Guanine with Antiproliferative Activity and Possible Utility in the Treatment of Human Papillomavirus Lesions (2009) (38)
Activities of Acyclic Nucleoside Phosphonates against Orf Virus in Human and Ovine Cell Monolayers and Organotypic Ovine Raft Cultures (2005) (38)
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations. (2005) (37)
Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives. (2007) (37)
Synthesis and antiviral activities of 8-alkynyl-, 8-alkenyl-, and 8-alkyl-2'-deoxyadenosine analogues. (1994) (37)
Activities of Alkoxyalkyl Esters of Cidofovir (CDV), Cyclic CDV, and (S)-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine against Orthopoxviruses in Cell Monolayers and in Organotypic Cultures (2006) (36)
Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia. (2015) (36)
Preparation of acyclo nucleoside phosphonate analogues based on cross-metathesis (2008) (36)
Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity. (1994) (36)
Mechanism of Antiviral Drug Resistance of Vaccinia Virus: Identification of Residues in the Viral DNA Polymerase Conferring Differential Resistance to Antipoxvirus Drugs (2008) (35)
The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations. (2007) (35)
Emergence of Cowpox: Study of the Virulence of Clinical Strains and Evaluation of Antivirals (2013) (35)
Synthesis and antiviral activity of carbocyclic oxetanocin analogues (C-OXT-A, C-OXT-G) and related compounds. II. (1993) (34)
Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain. (2000) (34)
Furano Pyrimidines as Novel Potent and Selective Anti-VZV Agents (2001) (34)
New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1. (1996) (33)
Epithelial raft cultures for investigations of virus growth, pathogenesis and efficacy of antiviral agents. (2010) (33)
4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus. (2009) (33)
Fluorescent bicyclic furo pyrimidine deoxynucleoside analogs as potent and selective inhibitors of VZV and potential future drugs for the treatment of chickenpox and shingles (2000) (33)
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations. (2009) (33)
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? (2004) (32)
Advances in the treatment of varicella-zoster virus infections. (2013) (31)
In vivo antiherpesvirus activity of N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine (1995) (31)
Inhibitory Activities of Three Classes of Acyclic Nucleoside Phosphonates against Murine Polyomavirus and Primate Simian Virus 40 Strains (2007) (31)
Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication. (1998) (31)
Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues (2014) (30)
Novel [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]- 3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2" -dioxide) derivatives with anti-HIV-1 and anti-human-cytomegalovirus activity. (2005) (30)
Emerging drugs for varicella-zoster virus infections (2011) (30)
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses. (2006) (30)
Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells (1998) (29)
An epimer of 5'-noraristeromycin and its antiviral properties. (1994) (29)
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique. (1991) (29)
Advances and Perspectives in the Management of Varicella-Zoster Virus Infections (2021) (29)
Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds. (2007) (29)
Design, Synthesis, and Molecular Docking Studies of a Conjugated Thiadiazole-Thiourea Scaffold as Antituberculosis Agents. (2016) (28)
Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine. (1998) (28)
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine. (2008) (27)
Basic chemokine-derived glycosaminoglycan binding peptides exert antiviral properties against dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus. (2016) (26)
Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds (1995) (26)
The Antiherpesvirus Activity of H2G [(R)-9-[4-Hydroxy-2-(Hydroxymethyl)Butyl]Guanine] Is Markedly Enhanced by the Novel Immunosuppressive Agent Mycophenolate Mofetil (1998) (26)
Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection. (2010) (26)
Spectrum of Activity and Mechanisms of Resistance of Various Nucleoside Derivatives against Gammaherpesviruses (2014) (26)
Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives. (2006) (26)
Viral DNA Polymerase Inhibitors (2009) (25)
Pyridine oxide derivatives: structure-activity relationship for inhibition of human immunodeficiency virus and cytomegalovirus replication in cell culture (2002) (25)
Synthesis and antiviral activity of three pyrazole analogues of distamycin A. (1994) (25)
6‐[2‐Phosphonomethoxy)Alkoxy]‐2,4‐Diaminopyrimidines: A New Class of Acyclic Pyrimidine Nucleoside Phosphonates with Antiviral Activity (2004) (25)
N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase (2013) (25)
Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase (2016) (25)
Dual infection with polyomavirus BK and acyclovir‐resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient (2007) (24)
Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3‐Triazolylbenzyl‐aminophosphonates (2015) (24)
Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives. (2000) (24)
Synthesis and antiviral activity of 5'-deoxypyrazofurin. (1993) (24)
Activity and Mechanism of Action of HDVD, a Novel Pyrimidine Nucleoside Derivative with High Levels of Selectivity and Potency against Gammaherpesviruses (2013) (24)
Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma (2015) (24)
Synthesis and biological properties of C-2 triazolylinosine derivatives. (2012) (24)
ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents. (2014) (24)
Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6-(Aminomethyl)purines and Purine-6-carboxamidines (1996) (23)
Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues. (2009) (23)
Specific Targeting of the F13L Protein by St-246 Affects Orthopoxvirus Production Differently (2008) (23)
Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus (1991) (23)
Inhibition of Vaccinia Virus Replication by Two Small Interfering RNAs Targeting B1R and G7L Genes and Their Synergistic Combination with Cidofovir (2009) (23)
S-Adenosyl-L-homocysteine Hydrolase Inhibitors as Anti-Viral Agents: 5′-Deoxyaristeromycin (1993) (23)
Comparative activity of various compounds against clinical strains of herpes simplex virus (1992) (22)
Current Pharmacological Approaches to the Therapy of Varicella Zoster Virus Infections (1999) (22)
Polyanion inhibitors of human immunodeficiency virus and other viruses. 6. Micelle-like anti-HIV polyanionic compounds based on a carbohydrate core. (1997) (22)
Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus. (2008) (22)
Differential Susceptibility of Several Drug-Resistant Strains of Herpes Simplex Virus Type 2 to Various Antiviral Compounds (1997) (22)
Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides. (1999) (22)
Polysulfonates Derived from Metal Thiolate Complexes as Inhibitors of HIV-1 and Various other Enveloped Viruses In Vitro (2002) (22)
Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides (2013) (22)
Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines. (2007) (22)
Serum, Pleural Effusion, and Ascites CA-125 Levels in Ovarian Cancer and Nonovarian Benign and Malignant Diseases: A Comparative Study (2002) (22)
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues (2015) (22)
Synthesis and Antiviral Evaluation of Phosphoramidate Derivatives of (E)-5-(2-Bromovinyl)-2′-Deoxyuridine (2001) (21)
Antiviral activity of ganciclovir elaidic acid ester against herpesviruses. (2000) (21)
Flow cytometric method for the detection of gpI antigens of varicella zoster virus and evaluation of anti-VZV agents. (1992) (21)
4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action. (2008) (21)
Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with AIDS. (1993) (21)
Novel agents for the therapy of varicella-zoster virus infections (2000) (21)
Synthesis and biological evaluation of some new 1,3,4-thiadiazole and 1,2,4-triazole derivatives from L-methionine as antituberculosis and antiviral agents (2015) (21)
Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core. (2007) (21)
New prodrugs of Adefovir and Cidofovir (2011) (21)
Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells (2011) (20)
Synthesis and Antiviral Activity of 1,3-Disubstituted Uracils against HIV-1 and HCMV (2003) (20)
Solvent-Free Synthesis of Pyrimidine Nucleoside-Aminophosphonate Hybrids and Their Biological Activity Evaluation (2010) (20)
Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants. (1995) (20)
Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): effect of terminal unsaturation in the side-chain. (2001) (20)
Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity. (2001) (20)
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity (2017) (20)
Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures (2016) (20)
A Rapid Phenotypic Assay for Detection of Acyclovir-Resistant Varicella-Zoster Virus with Mutations in the Thymidine Kinase Open Reading Frame (2000) (19)
Polyanion inhibitors of human immunodeficiency virus and other viruses. 5. Telomerized anionic surfactants derived from amino acids. (1997) (19)
Specific therapies for human papilloma virus infections. (1998) (19)
Anti-Varicella—Zoster Virus Bicyclic Nucleosides: Replacement of Furo by Pyrro Base Reduces Antiviral Potency (2000) (19)
From β‐Amino‐γ‐sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral Activities (2011) (19)
Antiviral and Cytostatic Evaluation of the Novel 6-acyclic Chain Substituted Thymine Derivatives (2005) (19)
Specific Inhibition of Orthopoxvirus Replication by a Small Interfering RNA Targeting the D5R Gene (2008) (19)
Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage (2013) (18)
Acyclovir-resistant herpes simplex encephalitis in a patient treated with anti-tumor necrosis factor-α monoclonal antibodies. (2014) (18)
Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof (2013) (18)
Evaluation of Novel Acyclic Nucleoside Phosphonates against Human and Animal Gammaherpesviruses Revealed an Altered Metabolism of Cyclic Prodrugs upon Epstein-Barr Virus Reactivation in P3HR-1 Cells (2013) (18)
Successful kinase bypass with new acyclovir phosphoramidate prodrugs. (2008) (18)
Thymidine kinase and protein kinase in drug-resistant herpesviruses: Heads of a Lernaean Hydra. (2018) (18)
Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids. (2004) (17)
Iron withdrawal strategies fail to prevent the growth of SiHa-induced tumors in mice. (2003) (17)
Mutations Conferring Resistance to Viral DNA Polymerase Inhibitors in Camelpox Virus Give Different Drug-Susceptibility Profiles in Vaccinia Virus (2012) (17)
Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives (2019) (17)
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs. (2017) (17)
Chemotherapy of varicella zoster virus infections. (1994) (17)
Norbornane-based nucleoside and nucleotide analogues locked in North conformation. (2015) (16)
Imidazothiadiazine dioxides: synthesis and antiviral activity. (1999) (16)
Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues. (2012) (16)
New Polyacetal Polysulphate Active against Human Immunodeficiency Virus and other Enveloped Viruses (1992) (16)
Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents. (2010) (16)
Iron as a potential cofactor in the pathogenesis of Kaposi's sarcoma (1999) (16)
Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes. (2000) (16)
Desferrioxamine enhances aids‐associated Kaposi's sarcoma tumor development in a xenograft model (2002) (16)
Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides. (1996) (16)
Synthesis and evaluation of antiviral , antitubercular and anticancer activities of some novel thioureas derived from 4-aminobenzohydrazide hydrazones (2010) (16)
Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis (2007) (16)
Skin mild hypoxia enhances killing of UVB-damaged keratinocytes through reactive oxygen species-mediated apoptosis requiring Noxa and Bim. (2012) (16)
Carbocyclic 5'-nor "reverse" fleximers. Design, synthesis, and preliminary biological activity. (2011) (15)
Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase. (2004) (15)
A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection (2014) (15)
Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues. (2011) (15)
A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity (2013) (15)
Bicyclic nucleoside inhibitors of Varicella-Zoster virus: the effect of branching in the p-alkylphenyl side chain. (2002) (14)
Discovery of novel furo[2,3‐d]pyrimidin‐2‐one–1,3,4‐oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis (2021) (14)
Sequestration of human cytomegalovirus by human renal and mammary epithelial cells. (2014) (14)
Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl)uracil derivatives (2006) (14)
Kaposi's sarcoma-associated herpesvirus: the role of lytic replication in targeted therapy (2015) (14)
Varicella-Zoster Virus ORF9p Binding to Cellular Adaptor Protein Complex 1 Is Important for Viral Infectivity (2018) (14)
Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 6-substituted purine and 8-azapurine. (1999) (14)
Dipyridamole Potentiates the Activity of Various Acyclic Nucleoside Phosphonates against Varicella-Zoster Virus, Herpes Simplex Virus and Human Cytomegalovirus (1994) (14)
Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor (2016) (14)
Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines. (2012) (14)
Synthesis and Anti-Varicella-Zoster Virus Activity of Some Novel Bicyclic Nucleoside Inhibitors: Effect of Enhanced Aqueous Solubility (2000) (14)
Synthesis, and cytotoxic activity of N(ind)-alkoxy derivatives of antibiotic arcyriarubin and dechloro-rebeccamycin aglycon. (2002) (14)
Influence of 4′-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2 (2020) (13)
Design, synthesis, chemical characterization, biological evaluation, and docking study of new 1,3,4-oxadiazole homonucleoside analogs (2020) (13)
Synthesis and SAR studies on azetidine-containing dipeptides as HCMV inhibitors (2010) (13)
Synthesis of 2'-aminomethyl derivatives of N-(2-(phosphonomethoxy)ethyl) nucleotide analogues as potential antiviral agents. (1996) (13)
New neplanocin analogues. VIII. Synthesis and biological activity of 6'-C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A. (1997) (13)
Bicyclic anti-VZV nucleosides: thieno analogues bearing an alkylphenyl side chain have reduced antiviral activity. (2004) (13)
Crystal Structure of (S)-1-Phenylethylammonium (R)-Mandelate and a Comparison of Diastereomeric Mandelate Salts of 1-Phenylethylamine. (1994) (13)
Structure—Antiviral Activity Relationship in the Series of Pyrimidine and Purine N-[2-(2-Phosphonomethoxy)ethyl] Nucleotide Analogues. Part 1. Derivatives Substituted at the Carbon Atoms of the Base. (1999) (13)
Synthesis and biological evaluation of acyclic nucleotide analogues with a furo(2,3-d)pyrimidin- 2(3H)-one base (2010) (13)
Synthetic Sulfur Carotenoids. III: Carotenoid Thiones -- First Preparation and Spectroscopic Properties. (1994) (12)
Synthesis and Anti‐herpetic Activity of Phosphoramidate ProTides (2013) (12)
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents. (2001) (12)
KAY-2-41, a Novel Nucleoside Analogue Inhibitor of Orthopoxviruses In Vitro and In Vivo (2013) (12)
Study of Camelpox Virus Pathogenesis in Athymic Nude Mice (2011) (12)
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization (2021) (12)
Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphono-but-2'-en-1'-yl]purine nucleosides. (2012) (12)
New Isoxazolidine-Conjugates of Quinazolinones—Synthesis, Antiviral and Cytostatic Activity (2016) (12)
Synthesis of Ester Prodrugs of 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as Anti-Poxvirus Agents (2010) (12)
Tricyclic etheno analogs of PMEG and PMEDAP: synthesis and biological activity. (2006) (12)
Antiviral activity spectrum of phenoxazine nucleoside derivatives (2019) (12)
Antiherpesvirus Activities of Two Novel 4′-Thiothymidine Derivatives, KAY-2-41 and KAH-39-149, Are Dependent on Viral and Cellular Thymidine Kinases (2014) (12)
Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of l-ascorbic or imino-l-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations (2015) (12)
Synthesis and antiviral activity of 6-chloropurine arabinoside and its 2'-deoxy-2'-fluoro derivative. (1996) (12)
Highlights of the 30th International Conference on Antiviral Research (2017) (11)
Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates (2016) (11)
Antiviral potential of “new” acyclic nucleoside phosphonates, the 6-[2-phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines (2004) (11)
Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety (2012) (11)
Mechanism of the Antiviral Activity of New Aurintricarboxylic Acid Analogues (1996) (11)
Novel carbocyclic nucleosides containing a cyclobutyl ring. Guanosine and adenosine analogues. (1998) (11)
Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides (2018) (11)
Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice. (2013) (11)
Antiviral Drug-Resistance Typing Reveals Compartmentalization and Dynamics of Acyclovir-Resistant Herpes Simplex Virus Type-2 (HSV-2) in a Case of Neonatal Herpes. (2014) (11)
Phosphonoamidate prodrugs of C5‐substituted pyrimidine acyclic nucleosides for antiviral therapy (2017) (11)
Synthesis and Antiviral Activity of 2 and 3-Substituted Imidazo[1,2-a]pyrimidine (1995) (11)
Synthesis of Imidazo[1,2-a]pyridine Derivatives as Antiviral Agents (2001) (11)
N(4)-Acyl derivatives as lipophilic prodrugs of cidofovir and its 5-azacytosine analogue, (S)-HPMP-5-azaC: chemistry and antiviral activity. (2014) (11)
Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms (2016) (11)
BICYCLIC NUCLEOSIDE INHIBITORS OF VARICELLA-ZOSTER VIRUS (VZV): EFFECT OF TERMINAL UNSATURATION IN THE SIDE-CHAIN (2001) (11)
Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity (2013) (10)
Novel Isoxazolidine and γ-Lactam Analogues of Homonucleosides (2019) (10)
Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. (2017) (10)
Synthesis and biological evaluation of bicyclic furano pyrimidine nucleosides as inhibitors of human cytomegalovirus (2003) (10)
Amidate Prodrugs of Cyclic 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity. (2018) (10)
Ovine Skin Organotypic Cultures Applied to the Ex vivo Study of Orf Virus Infection (2005) (10)
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir (2013) (10)
Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring (1999) (10)
Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates (2018) (10)
Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives (2010) (10)
SYNTHESIS OF AMINO ACIDS WITH MODIFIED PRINCIPAL PROPERTIES. III: SULFUR-CONTAINING AMINO ACIDS (1994) (9)
Synthesis and Antiviral Activities of Some Novel Carbocyclic Nucleosides (1996) (9)
Synthesis and Antiviral Activity of 6-Benzoyl-Benzoxazolin-2-One and 6-Benzoyl-Benzothiazolin-2-One Derivatives (1999) (9)
In vitro Sensitivity of Kaposi's Sarcoma Cells to Various Chemotherapeutic Agents Including Acyclic Nucleoside Phosphonates (1999) (9)
Sonication-Assisted Synthesis of (E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs (2016) (9)
CRISPR/Cas9 Editing of the Polyomavirus Tumor Antigens Inhibits Merkel Cell Carcinoma Growth In Vitro (2019) (9)
The Anti–Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase (2018) (9)
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses (2021) (9)
Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation (2021) (9)
SYNTHESIS AND ANTI-HIV ACTIVITY OF THYMIDINE ANALOGUES BEARING A 4′-CYANOVINYL GROUP AND SOME DERIVATIVES THEREOF (2001) (9)
Design, synthesis and biological evaluation of 2′-deoxy-2′,2′-difluoro-5-halouridine phosphoramidate ProTides (2011) (9)
Bicyclic Nucleoside Inhibitors of Varicella-Zoster Virus: Synthesis and Biological Evaluation of 2′,3′-Dideoxy- 3′-fluoro and 2′-Deoxy-xylo Derivatives (2003) (8)
Phosphonylated Acyclic Guanosine Analogues with the 1,2,3-Triazole Linker (2015) (8)
Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV). (2007) (8)
An Epimer of 5′-Noraristeromycin and Its Antiviral Properties. (1994) (8)
2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. (2009) (8)
Meeting report: 32nd International Conference on Antiviral Research (2013) (8)
Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis (2017) (8)
Antiviral Activity of 3-(3,5-Dimethylbenzyl)Uracil Derivatives Against Hiv-1 and HCMV (2007) (8)
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro (1996) (8)
The cytostatic activity of 5‐(1‐azidovinyl)‐2′‐deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene‐transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (λ = 254 nm) exposure (1995) (8)
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: Efficient synthesis and antiviral activity (2011) (8)
Synthesis and Antiviral Evaluation of Some 3′‐Fluoro Bicyclic Nucleoside Analogues (2004) (8)
Novel bicyclic furanopyrimidines with dual anti-VZV and -HCMV activity. (2003) (8)
Phenotypic Resistance of Herpes Simplex Virus Type 1 Strains Selected in Vitro with Antiviral Compounds and Combinations Thereof (1996) (8)
Metabolic and Pharmacological Characteristics of the Bicyclic Nucleoside Analogues (BCNAs) as Highly Selective Inhibitors of Varicella-Zoster Virus (VZV) (2003) (8)
BICYCLIC FURO PYRIMIDINE NUCLEOSIDES WITH ARYLOXYPHENYL AND HALOPHENYL SUBSTITUTED SIDE CHAINS AS POTENT AND SELECTIVE VARICELLA-ZOSTER VIRUS INHIBITORS (2001) (8)
Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus. (2009) (8)
Monitoring drug resistance for herpesviruses. (2000) (7)
Bicyclic Nucleoside Inhibitors of Varicella-Zoster Virus (VZV): Pd-Catalysed Synthesis of 5-aryl Derivatives and Their Biological Evaluation (2001) (7)
Virtual Screening of Acyclovir Derivatives as Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside ProTides. (2017) (7)
Vaccines and Antivirals: Grand Challenges and Great Opportunities (2021) (7)
Human cytomegalovirus (HCMV) strains selected under selective pressure of phosphonoformate (PFA) are resistant for both PFA and phosphonylmethoxyethyl (PME) derivatives in vitro (1995) (7)
Evaluating phenotype and genotype of drug-resistant strains in herpesviruses (2001) (7)
Synthesis and Bioactivity of Novel Trisubstituted Triazole Nucleosides (2016) (7)
(±)-7-deazaaristeromycin lacking the hydroxymethyl substituent (1993) (7)
Bicyclic Nucleoside Inhibitors of Varicella-Zoster Virus Modified on the Sugar Moiety: 3′ and 5′ Derivatives (2004) (7)
Evaluation of Novel Phosphoramidate ProTides of the 2′-Fluoro Derivatives of a Potent Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogue (2010) (7)
Preparation of Some Acetylated Deoxy-pento- and -hexofuranoses and their Deacetylation. (1994) (7)
Cyclopentene carbocyclic nucleosides related to the antitumor nucleoside clitocine and their conversion to 8-aza-neplanocin analogues. Synthesis and antiviral activity (1993) (7)
Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3‐Triazole Nucleosides (2017) (7)
Formulation of acyclovir (core)-dexpanthenol (sheath) nanofibrous patches for the treatment of herpes labialis. (2021) (7)
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV). (2017) (7)
Facile preparation of 9-H-pyrimido [4,5-b] [1,4] diazepine derivatives from 4,5-diaminopyrimidines and ethyl pyruvate. (1994) (7)
Isoxazolidine Conjugates of N3-Substituted 6-Bromoquinazolinones—Synthesis, Anti-Varizella-Zoster Virus, and Anti-Cytomegalovirus Activity (2018) (7)
Meeting report: 31st International Conference on Antiviral Research (2018) (7)
A European multi-centre External Quality Assessment (EQA) study on phenotypic and genotypic methods used for Herpes Simplex Virus (HSV) drug resistance testing. (2017) (7)
Emimycin and its nucleoside derivatives: Synthesis and antiviral activity. (2018) (6)
Synthesis and Biological Activity of Some 2-Aminopurine Carbonucleosides (1997) (6)
Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss. (2019) (6)
Therapy of poxvirus infections (2007) (6)
Bicyclic Nucleoside Inhibitors of Varicella-Zoster Virus: 5′-Chloro and 3′-Chloro Derivatives (2003) (6)
Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro (1992) (6)
Mutations in adenosine deaminase-like (ADAL) protein confer resistance to the antiproliferative agents N6-cyclopropyl-PMEDAP and GS-9219. (2013) (6)
Synthesis, Anti-varicella-zoster virus and Anti-cytomegalovirus Activity of 4,5-Disubstituted 1,2,3-(1H)-Triazoles. (2019) (6)
Synthesis of 4′-substituted 2′-deoxy-4′-thiocytidines and its evaluation for antineoplastic and antiviral activities (2019) (6)
Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance (2022) (6)
Toward the discovery of dual HCMV–VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides (2015) (6)
Human Brain Tumour Cell Lines as Cell Substrate to Demonstrate Sensitivity/Resistance of Herpes Simplex Virus Types 1 and 2 to Nucleoside Analogues (1994) (6)
Substituted adamantylphthalimides: Synthesis, antiviral and antiproliferative activity (2020) (6)
Amidate Prodrugs of O-2-Alkylated Pyrimidine Acyclic Nucleosides Display Potent Anti-Herpesvirus Activity. (2020) (6)
Halophenyl Furanopyrimidines as Potent and Selective Anti-VZV Agents (2003) (5)
Synthesis of uracil–coumarin conjugates as potential inhibitors of virus replication (2019) (5)
Synthesis of 2′‐Aminomethyl Derivatives of N‐(2‐(Phosphonomethoxy) ethyl) Nucleotide Analogues as Potential Antiviral Agents. (1996) (5)
Comparison of exoEasy Maxi kit (Qiagen) with size-exclusion chromatography qEV columns (Izon Science) for isolation of extracellular vesicles from human plasma (2016) (5)
Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues (2020) (5)
SYNTHESIS AND IN VITRO EVALUATION OF NOVEL ANTI-VARICELLA-ZOSTER VIRUS (VZV) NUCLEOSIDES (2001) (5)
Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1 (2016) (5)
Bicyclic Nucleoside Inhibitors of Varicella‐Zoster Virus (VZV): The Effect of a Terminal Halogen Substitution in the Side‐Chain. (2000) (5)
Tenofovir Activating Kinases May Impact the Outcome of HIV Treatment and Prevention (2015) (5)
BKTyper: Free Online Tool for Polyoma BK Virus VP1 and NCCR Typing (2020) (5)
Alkyloxyphenyl Furano Pyrimidines as Potent and Selective Anti-VZV Agents with Enhanced Water Solubility (2002) (5)
Antiviral activity of 2-phosphonomethoxyalkyl derivatives of N6-substituted 6-aminopurines (1995) (5)
Nucleosides and Nucleotides. Part 148. New Neplanocin Analogues. Part 6. Synthesis and Potent Antiviral Activity of 6′-Homoneplanocin A. (1996) (5)
Antiviral and Cytostatic Evaluation of 5‐(1‐Halo‐2‐sulfonylvinyl)‐ and 5‐(2‐Furyl)uracil Nucleosides (2017) (5)
Palladium-catalyzed synthesis of (E)-5-(2-acylvinyl)-2′-deoxyuridines and their antiviral and cytotoxic activities (1995) (5)
Novel isoxazolidine analogues of homonucleosides and homonucleotides (2016) (5)
Synthesis and Evaluations of “1,4‐Triazolyl Combretacoumarins” and Desmethoxy Analogs (2019) (5)
6-[2-(Phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines: A New Class of Acyclic Pyrimidine Nucleoside Phosphonates with Antiviral Activity (2005) (5)
NOVEL ARYL SUBSTITUTED BICYCLIC FURO NUCLEOSIDES AS EXTREMELY POTENT AND SELECTIVE ANTI-VZV AGENTS (2001) (5)
Studies of Phase Equilibria in the System MgO--Mo--O in the Temperature Range 1100--1400 K. (1994) (4)
Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates. (2018) (4)
Combination of azidothymidine (AZT) and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) inhibits the replication of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) and varicella zoster virus (VZV) strains that are deficient in the expression of the viral thymidine kinase (TK) (1995) (4)
XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis (2021) (4)
Exploring the purine core of 3′-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics (2016) (4)
THE JOURNEY TOWARDS ELUCIDATING THE ANTI-HCMV ACTIVITY OF ALKYLATED BICYCLIC FURANO PYRIMIDINES (2005) (4)
Thienothiadiazine 2,2-Dioxide Acyclonucleosides: Synthesis and Antiviral Activity (2000) (4)
New acetamide derivatives containing (ω-p-bromophenoxyalkyl)uracil moiety and their anticytomegalovirus activity (2020) (4)
Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products. (2017) (4)
Viral fitness of MHV-68 viruses harboring drug resistance mutations in the protein kinase or thymidine kinase. (2020) (4)
Design, synthesis and antiviral evaluation of novel acyclic phosphonate nucleotide analogs with triazolo[4,5-b]pyridine, imidazo[4,5-b]pyridine and imidazo[4,5-b]pyridin-2(3H)-one systems (2020) (4)
Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient. (2016) (4)
Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues (1997) (4)
Synthesis of Acyclo‐C‐nucleosides in the Imidazo(1,2‐a)pyridine and ‐ pyrimidine Series as Antiviral Agents. (1996) (4)
Synthesis of O[2]- and N[3]-(2-phosphonomethoxy)ethyl derivatives of 6-phenyl- and 6-pyridinyl-5-azacytosine (2011) (4)
Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo. (2002) (4)
Lymphocyte‐independent pathways underlie the pathogenesis of murine cytomegalovirus‐associated secondary haemophagocytic lymphohistiocytosis (2018) (3)
Synthesis of 3',4'-difluoro-3'-deoxyribonucleosides and its evaluation of the biological activities: discovery of a novel type of anti-HCV agent 3',4'-difluorocordycepin. (2014) (3)
Synthesis and anti-HCMV Activity of 1-Acyl-β-lactams and 1-Acylazetidines Derived from Phenylalanine. (2004) (3)
Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice (2018) (3)
In vivo antiviral activity of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine and its cyclic form (2007) (3)
Phosphonylated 8-Azahypoxantines as Acyclic Nucleotide Analogs (2015) (3)
SAR of alkyloxyphenyl furano pyrimidines: Potent and selective anti-VZV agents (2006) (3)
Acyclovir Resistance in Herpes Simplex Viruses: Prevalence and Therapeutic Alternatives. (2022) (3)
Uracil-Containing Heterodimers of a New Type: Synthesis and Study of Their Anti-Viral Properties (2020) (3)
Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety (2019) (3)
Preparation of O-Hydroxyethyl and O-Hydroxypropyl Derivatives of D-Glucose and 2-Acetamido-2-deoxy-D-glucose for Studies of Modified Hyaluronic Acid. (1994) (3)
Insight into non-nucleoside triazole-based systems as viral polymerases inhibitors. (2023) (3)
Synthesis of [11C]Cyanoalkylphosphoranes and their Use in the Preparation of 11C-Olefins. (1994) (3)
Synthesis of Unusual Bicyclic Nucleosides Bearing an Unsaturated Side-Chain, as Potential Inhibitors of Varicella-Zoster Virus (VZV) (2003) (3)
Chemistry of Niobium Chlorides in the CsCl--NaCl Eutectic Melt. 1. Electromotive Force Measurements of NbCl3 in the CsCl--NaCl Eutectic Melt at Temperatures between 600 and 700 degrees C. (1994) (3)
Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus (2018) (3)
HYDROXYLATED PCB DERIVATIVES. SYNTHESIS AND STRUCTURE ELUCIDATION BY NMR SPECTROSCOPY AND X-RAY DIFFRACTION (1994) (3)
Synthesis and Antiviral Activity of 5′-Deoxypyrazofurin. (1994) (3)
Bicyclic Nucleoside Inhibitors of Varicella-Zoster Virus: Effect of Terminal Aryl Substitution in the Side-Chain (2002) (3)
Cidofovir: Induction of apoptosis in human papilloma virus (HPV)-containing cell lines (1997) (3)
2-(2,4-Dioxy-1,2,3,4-Tetrahydropyrimidin-1-yl)-N-(4-Phenoxyphenyl)-Acetamides as a Novel Class of Cytomegalovirus Replication Inhibitors (2015) (3)
Synthesis and Antiviral Activity of Acyclic Nucleotide Analogues Derived from 6‐(Aminomethyl)purines and Purine‐6‐carboxamidines. (1997) (2)
Susceptibilities of several drug-resistant varicella-zoster virus (VZV) strains to bicyclic pyrimidine nucleoside analogues (BCNAs) (2002) (2)
Non-Nucleoside Structures Retain Full Anti-HCMV Potency of the Dideoxy Furanopyrimidine Family (2004) (2)
Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives (2019) (2)
Antiviral drug susceptibility of herpes simplex type 1 (HSV-1) strains emerging under the selective pressure of (S)-1-(3-Hydroxy-2-Phosphonylmethoxypropyl)cytosine (HPMPC) in vitro (1995) (2)
Antiviral Potency of ST-246 on the Production of Enveloped Orthopoxviruses and Characterization of ST-246 Resistant Vaccinia, Cowpox and Camelpox Viruses (2008) (2)
SYNTHESIS AND BIOLOGICAL EVALUATION OF N- AND O-ALKYLATED BICYCLIC FURANOPYRIMIDINES AS NON-NUCLEOSIDIC INHIBITORS OF HUMAN CYTOMEGALOVIRUS (2005) (2)
Acyclic nucleoside phosphonates containing the amide bond (2016) (2)
New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity (2022) (2)
Bicyclic Nucleoside Inhibitors of Varicella—Zoster Virus: The Effect of Branching in the p-Alkylphenyl Side Chain. (2006) (2)
Carbocyclic Oxetanocins Lacking the C-3′ Methylene. (2010) (2)
Design, Synthesis, and Biological Evaluation of Novel C5-Modified Pyrimidine Ribofuranonucleosides as Potential Antitumor or/and Antiviral Agents. (2020) (2)
Dual anti-HSV and anti-HIV activity of the lantibiotic Labyrinthopeptin A1 (2014) (2)
Extension of furopyrimidine nucleosides with 5-alkynyl substituent: Synthesis, high fluorescence, and antiviral effect in the absence of free ribose hydroxyl groups (2020) (2)
Organotypic Epithelial Raft Cultures as a Three-Dimensional In Vitro Model of Merkel Cell Carcinoma (2022) (2)
Synthesis and Antiviral Properties of 1-Substituted 3-[ω-(4-Oxoquinazolin-4(3H)-yl)alkyl]uracil Derivatives (2020) (2)
Efficacy of PMEG [9-(2-phosphonylmethoxyethyl)-guanine] and its prodrug cPr-PMEDAP [9-(2-phosphonylmethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine in organotypic cultures of normal and papillomavirus ((HPV)-positive keratinocytes (2004) (2)
Design, synthesis and biological evaluation of novel acyclovir protides (2008) (2)
Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs (2018) (2)
Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2 (2022) (2)
Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections (2021) (2)
Acyclic Nucleotide Analogues Derived from 8-Azapurines: Synthesis and Antiviral Activity. (2010) (2)
Synthesis, antiviral, cytotoxic and cytostatic evaluation of N1-(phosphonoalkyl)uracil derivatives (2016) (2)
Practical and Efficient Synthesis of Pyrano[3,2‐c]pyridone, Pyrano[4,3‐b]pyran and Their Hybrids with Nucleoside as Potential Antiviral and Antileishmanial Agents. (2010) (2)
Methods in Anti-HCMV Research. (2000) (2)
Synthesis of 5,5-difluoro-5-phosphono-pent-2-en-1-yl nucleosides as potential antiviral agents (2017) (2)
Selection and characterization of (S)-1-[3-hydroxy-2-(phosphonomethoxypropyl)-2,6-diaminopurine [HPMPDAP] resistant camelpox viruses (2009) (2)
New bicyclic nucleoside analogues (BCNAs) show selective and specific activity against human cytomegalovirus (HCMV) (2003) (1)
Antiviral Activity of 3‐(3,5‐Dimethylbenzyl)uracil Derivatives Against HIV‐1 and HCMV (2008) (1)
Synthesis and antiviral activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil against HIV-1. (2004) (1)
Influence of the 2-Substituent on the Activity of Imidazo[1,2-a]pyridine Derivatives Against Human Cytomegalovirus. (2002) (1)
Synthesis and Antiviral Evaluation of Some 3′-Fluoro Bicyclic Nucleoside Analogues. (2004) (1)
New therapeutic weapons against poxvirus (2008) (1)
Pre-clinical development of the BCNAs: The most potent anti-VZV agents reported to date (2006) (1)
Is the large T antigen a target for the inhibition of SV40 replication (2010) (1)
Differential antiviral activity of several IMP dehydrogenase inhibitors (1997) (1)
Bicyclic Furo Pyrimidine Nucleosides with Aryloxyphenyl and Halophenyl Substituted Side Chains as Potent and Selective Varicella—Zoster Virus Inhibitors (2001) (1)
Putting drug resistant epithelial herpes keratitis in the spotlight: A case series (2022) (1)
Antiviral Activities of New Cidofovir Analogs Against Camelpox Virus, Used as a Model of Variola Virus, in Human Skin Equivalent Cultures (2007) (1)
Inhibiting effects of PMEG [9-(2-phosphonylmethoxyethyl)guanine] on the growth of human cervical carcinoma xenografts in athymic nude mice (2005) (1)
T-705 and ribavirin induce lethal mutagenesis of influenza virus (2015) (1)
Activity of novel acyclic pyrimidine nucleoside phosphonates against poxviruses (2004) (1)
Acute primary infection with mouse cytomegalovirus represents a natural animal model for virus-associated secondary hemophagocytic lymphohistiocytosis (2014) (1)
Synthesis and Biological Evaluation of Acyclic Nucleotide Analogues of Bicyclic Pyrimidine Bases (2009) (1)
Identification of Bicyclic Sulfone Inhibitors of HHV-6 Targeting the HHV-6 U77 Helicase (2011) (1)
Labyrinthopeptin A1, a novel lantibiotic peptide, is a dual HIV and HSV entry inhibitor (2013) (1)
Specific phosphorylation of 2-amino-7-[(1,3-dihydroxy-2-propoxymethyl)purine (S2242) in human cytomegalovirus-infected human embryonic lung fibroblasts (1995) (1)
Selective Inhibitors of Nuclear Export (SINE) Compounds Suppress Both HIV Replication and AIDS Related Lymphoma (2015) (1)
Characterization of cowpox virus (CPV) mutants arising under pressure with different acyclic nucleoside phosphonates (2009) (1)
Synthesis and antiviral activity of various N4-acyl derivatives of cidofovir and its 5-azacytosine counterpart, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine (2008) (1)
Metabolic and Pharmacological Characteristics of the Bicyclic Nucleoside Analogues (BCNAs) as Highly Selective Inhibitors of Varicella—Zoster Virus (VZV) (2004) (1)
Synthesis and Antiviral Evaluation of 3-(2,3-Dihydroxypropyl)furo[2,3-d]pyrimidin-2(3H)-ones (2010) (1)
Identification of the type of cells responsible for transfer of herpes simplex virus (HSV) and vaccinia virus (VACV) infection to epithelial cells grown in 3D (2009) (1)
N-[2-Hydroxyethoxy)methyl] derivatives of bicyclic furano and pyrrolo pyrimidines and their antiviral evaluation (2004) (1)
Phosphoramidate prodrugs of the most potent and selective anti-VZV bicyclic pyrimidine nucleosides (2005) (1)
Heterogeneity and viral replication fitness of HSV-1 clinical isolates with mutations in the thymidine kinase and DNA polymerase. (2022) (1)
Design and synthesis of a new series of hybrids of functionalised N1-[(1H-1,2,3-triazol-4-yl)methyl]quinazoline-2,4-dione with antiviral activity against Respiratory Syncytial Virus. (2022) (1)
An efficient synthesis and antiviral activity evaluation of 1-[4-(5-phenyl-4, 5 dihydro-1H-pyrazole [& (4, 5 dihydroisoxazole)]-3-yl)-phenyl]-pyrrole-2, 5-dione derivates (2014) (1)
Sonication-Assisted Synthesis of (E)-2-Methyl-but-2-enyl Nucleoside Phosphonate Prodrugs. (2016) (1)
Lignosulfonic acid exhibits broad-spectrum anti-HIV and anti-HSV activity and has potential for microbicidal applications (2014) (1)
Synthesis of new 3-acetyl-1,3,4-oxadiazolines combined with pyrimidines as antileishmanial and antiviral agents (2022) (1)
Acyclic nucleoside phosphonates containing the amide bond: hydroxy derivatives (2019) (1)
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines: a new class of acyclic pyrimidine nucleoside phosphonates with antiviral activity (2003) (1)
Bicyclic anti-VZV nucleosides: Thieno analogues bearing alkylphenyl side chain result in a reduction in antiviral activity (2004) (1)
Cyclopentene Carbocyclic Nucleosides Related to the Antitumor Nucleoside Clitocine and Their Conversion to 8-Aza-neplanocin Analogues. Synthesis and Antiviral Activity. (1994) (1)
Bicyclic anti‐VZV Nucleosides: Thieno Analogues Bearing an Alkylphenyl Side Chain Have Reduced Antiviral Activity. (2004) (1)
Bicyclic Nucleoside Inhibitors of Varicella—Zoster Virus: Synthesis and Biological Evaluation of 2′,3′‐Dideoxy‐3′‐fluoro and 2′‐Deoxy‐xylo Derivatives (2004) (1)
Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity (2018) (1)
Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping. (2015) (1)
Synthesis and Cytotoxic Activity of Nind-Alkoxy Derivatives of Antibiotic Arcyriarubin and Dechloro-rebeccamycin Aglycon. (2003) (1)
New antiviral agent, 1-( S )-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: esters and base-modified derivatives (2008) (1)
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir (2013) (1)
Anti‐HCMV Compounds (2011) (1)
Bicyclic Nucleoside Inhibitors of Varicella—Zoster Virus: 5′-Chloro and 3′-Chloro Derivatives (2004) (1)
Synthesis of O2‐ and N3‐(2‐Phosphonomethoxy)ethyl Derivatives of 6‐Phenyl‐ and 6‐Pyridinyl‐5‐azacytosine. (2011) (1)
Reduced pathogenicity of phenotypically and genotypically characterized cidofovir (CDV)-resistant vaccinia virus (VV) (2005) (1)
CMV423, a potent and selective inhibitor of human herpesvirus 6 exerts its antiviral action through inhibition of cellular protein tyrosine kinase activity (2003) (0)
Interaction of the bicyclic nucleoside analogues (BCNAs) with human varicella-zoster virus (VZV) and simian varicella virus (SVV) thymidine kinase and VZV DNA polymerase (2003) (0)
Introduction to the Special Issue dedicated to Prof. Erik De Clercq for reaching the Professor Emeritus status at the Katholieke Universiteit Leuven (2006) (0)
Cidofovir selectivity is based on the different response of normal and cancer cells to DNA damage (2013) (0)
Derivatives of 3'‐Azidothymidine with 6‐Cyanopyridone as Base or as Phosphoramidate Ester and their Antiretroviral Activity (2022) (0)
Nucleosides and Nucleotides. Part 149. New Neplanocin Analogues. Part 7. Synthesis and Antiviral Activity of 2-Halo Derivatives of Neplanocin A. (1997) (0)
Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis (2017) (0)
Design, Synthesis, Anti-Varicella-Zoster and Antimicrobial Activity of (Isoxazolidin-3-yl)Phosphonate Conjugates of N1-Functionalised Quinazoline-2,4-Diones (2022) (0)
Mode of action of cidofovir against human papillomavirus positive and negative cells is not exclusively due to DNA damage (2014) (0)
Synthesis and Antiviral Activity of 6‐Chloropurine Arabinoside and Its 2′‐Deoxy‐2′‐fluoro Derivative. (1997) (0)
Isolation of vaccinia virus (VV) mutants resistant to different acyclic nucleoside phosphonate analogues (ANPs) (2004) (0)
Mononuclear cells as a transfer vehicle for herpes simplex virus (HSV) or vaccinia virus (VV) infection of epithelial cells grown in 3D (2007) (0)
Development of a Model for the Study of Antivirals Against Molluscum Contagiosum Virus (MCV) (2008) (0)
Activity of hydroxyurea (HU) in combination with several antiviral nucleosides against in vitro replication of herpes simplex type 1 (HSV-1) and type 2 (HSV-2) and varicella-zoster virus (VZV) (1995) (0)
Synthesis and antiviral properties of biomimetic iminosugar-based nucleosides. (2022) (0)
XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis (2021) (0)
KAH-39-149, Are Dependent on Viral and -Thiothymidine Derivatives, KAY-2-41 and ' Antiherpesvirus Activities of Two Novel 4 (2014) (0)
Activity of D- and L-enantiomers of cyclohexenyl guanine against herpesviruses (2000) (0)
Synthesis and Antiviral Evaluation of N9-[2-(Phosphonomethoxy)ethyl] (PME) Analogues Derived from 8-Substituted Purines (2011) (0)
Antiviral activity of a novel compound P-4018 against different strains of herpes simplex virus in vitro and in vivo (1997) (0)
Novel bicyclic fluorescent nucleosides as potent and selective inhibitors of VZV (2000) (0)
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (Cidofovir®, HPMPC) is a potent inhibitor of murine polyomavirus replication both in vitro and in vivo (1995) (0)
Quinoline‐Dihydropyrimidin‐2(1H)‐one Hybrids: Synthesis, Biological Activity, and Mechanistic Studies (2022) (0)
Highly potent and selective inhibitors of varicella zoster virus based on p-alkyloxyphenyl bicyclic furo pyrimidines (2002) (0)
2′-Fluorosugar Analogues of the Highly Potent anti-Varicella-Zoster Virus Bicyclic Nucleoside Analogue (BCNA) Cf 1743. (2010) (0)
Synthesis and Antiviral Activity of 3‐Substituted Imidazo(1,2‐a) pyridines. (1995) (0)
Anti-herpesvirus Activity of Two Novel 4 ’-Thiothymidine Derivatives KAY-2-41 and KAH-39-149 is 1 dependent on viral and cellular thymidine kinases 2 3 4 (2014) (0)
Bicyclic furo pyrimidine nucleosides with haloaryl side chains (2003) (0)
Synthesis and biological evaluation of a new series of 5-alkylaryl nucleoside analogues showing anti-HCMV activity (2003) (0)
Synthesis and antiviral evaluation of N9-[2-(phosphonomethoxy)ethyl] (PME) analogues derived from 8-substituted purine (2011) (0)
Solvent-Free Synthesis of Pyrimidine Nucleoside-Aminophosphonate Hybrids and Their Biological Activity Evaluation. (2011) (0)
Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of β-D-N4-hydroxycytidine (NHC) and a 3′-fluoro-substituted analogue of NHC (2023) (0)
Broad-spectrum antiviral activity of polyoxometalates against human immunodeficiency virus and other enveloped viruses (1992) (0)
Activity of alkoxyalkyl and alkyl esters of (S)-3-hydroxy-2-phosphonylmethoxypropyl derivatives of cytosine (HPMPC, cidofovir) and adenine (HPMPA) and cyclic cidofovir against orthopoxviruses in vitro and in organotypic epithelial raft cultures (2005) (0)
Design, synthesis and evaluation of novel Anti-VZV BCNAs (2008) (0)
Organotypic epithelial raft cultures as a model for evaluation of antivirals against varicella-zoster virus (VZV) (2006) (0)
Perspectives for the treatment of human papillomavirus infections (1995) (0)
Antiviral activity of acyclic nucleoside phosphonates with branched 2-(2-phosphonoethoxy)ethyl chain (2010) (0)
An MHV-68 Mutator Phenotype Mutant Virus, Confirmed by CRISPR/Cas9-Mediated Gene Editing of the Viral DNA Polymerase Gene, Shows Reduced Viral Fitness (2021) (0)
Towards the optimization of azetidine-containing dipeptides as human cytomegalovirus inhibitors (2008) (0)
Twenty-Fourth International Conference on Antiviral Research - Front Pages (2011) (0)
The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, cytostatic and antiviral evaluations (2004) (0)
Multidrug-resistant cytomegalovirus infection in a pediatric stem cell transplantation patient (2016) (0)
Differing SARs and MOAs emerge for the highly potent anti-VZV, BCNAs, and their anti-HCMV dd analogues (2004) (0)
New non-nucleoside inhibitors of cytomegalovirus (2007) (0)
Some modifications to the bicyclic pyrimidines: a novel class of anti-viral nucleosides (2006) (0)
Intracellular metabolism of the novel anti-herpesvirus agent 2-amino-7-[1,3-dihydroxy-2-propoxy)methyl]purine compound S2242 in non-infected and herpesvirus-infected cells (1995) (0)
Synthesis and in vitro Evaluation of Novel anti‐Varicella‐Zoster Virus (VZV) Nucleosides (2001) (0)
Characterization of drug-resistant herpes simplex virus type 1 (HSV-1) mutants obtained under single-round selection with high-dose brivudin (BVDU) (2002) (0)
Synthesis of Unusual Bicyclic Nucleosides Bearing an Unsaturated Side-Chain, as Potential Inhibitors of Varicella—Zoster Virus (VZV) (2004) (0)
Genotypic characterization of various herpes simplex virus type 1 (HSV-1) clones resistant to acyclic nucleoside phosphonates (1997) (0)
ISAR News (2018) (0)
Highlights on the mode of action of ST-246, an anti-orthopoxviral compound (2008) (0)
Author response: A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection (2014) (0)
Heparan sulfate proteoglycan-binding chemokine peptides as inhibitors of dengue virus serotype 2, herpes simplex virus-1 and respiratory syncytial virus (2015) (0)
Characterization of varicella-zoster virus (VZV) mutants resistant to bicyclic pyrimidine nucleoside analogues (BCNAs) (2003) (0)
Anti-tumor effect of cidofovir against human papillomavirus positive and negative cells is not exclusively due to DNA damage (2015) (0)
Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: structure-activity relationships and mechanism of action (2008) (0)
As antivirals appropriate azacytosinderivate (2006) (0)
Chemical stability and intracellular metabolism of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine (2007) (0)
Drug susceptibility profiles of recombinant vaccinia virus harboring mutation(s) conferring resistance to cidofovir (2006) (0)
Design and synthesis of novel anti-HCMV agents: Modifications to the bicyclic pyrimidine base (2007) (0)
Mouse cytomegalovirus infection in BALB/c mice resembles virus-associated secondary hemophagocytic lymphohistiocytosis (HLH) and shows a pathogenesis distinct from primary HLH (2015) (0)
Synthesis and antiviral activity of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine and its ester prodrugs (2007) (0)
Antiviral activity of D- and L-enantiomers of cyclohexenyl guanine (2000) (0)
β-lactam analogs of oxetanocins – synthesis and biological activity (2022) (0)
Structure-activity relationship of a novel class of Aglycoristocetin derivatives with potent and broad activity against influenza viruses (2009) (0)
Antiviral activity of the non-nucleoside analogue CMV423 in lymphoblast cells infected with human herpesvirus 6 (2000) (0)
Facile Preparation of 9‐H‐Pyrimido(4,5‐b)(1,4)diazepine Derivatives from 4,5‐Diaminopyrimidines and Ethyl Pyruvate. (1995) (0)
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC): A new approach for the treatment of human papillomavirus (HPV-induced tumors (1995) (0)
Polyomavirus BK Genome Comparison Shows High Genetic Diversity in Kidney Transplant Recipients Three Months after Transplantation (2022) (0)
Acyclic/Carbocyclic Guanosine Analogues as Anti‐Herpesvirus Agents (2001) (0)
Activity of 7,8-dihydro-isoquinoline-6-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-amide hydrochloride salt against human cytomegalovirus (HCMV) (2002) (0)
Pharmacological properties of the novel anti-varicella-zoster virus bicyclic nucleoside analogues (BCNAs) (2002) (0)
Synthesis, Cytostatic and Antiviral Evaluations of the New C-5 Substituted Pyrimidine and Furo[2, 3-d]pyrimidine 4, 5-Didehydro-L-ascorbic Acid Derivatives (2008) (0)
Activity of 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines against polyomaviruses (2006) (0)
Synthesis and Antiviral Activities of Some Novel Carbocyclic Nucleosides. (1996) (0)
Combination of azidothymidine (AZT) with (E)-5-(2-bromovinyl)-2′-deoxyuridine (BVDU) leads to inhibition of the in vitro replication of herpes simplex virus type 1 (HSV-1), type 2 (HSV-2) and varicella-zoster virus (VZV) strains that are deficient in thymidine kinase (TK) activity (1995) (0)
Infection of different human tumor cell lines by human cytomegalovirus (1991) (0)
Synthesis and anti‐HIV Activity of Thymidine Analogues Bearing a 4′‐Cyanovinyl Group and Some Derivatives Thereof. (2002) (0)
Comparative Activity of Selected Acyclic Nucleoside Phosphonates (ANPs) in a Lethal Model of Vaccinia Virus (VACV) Infection (2008) (0)
Comparison of membrane affinity-based method with size-exclusion chromatography for isolation of exosome-like vesicles from human plasma (2018) (0)
Successful treatment of severe relapsing anogenital papillomavirus infections in AIDS patients with (S)-1-(3-Hydroxy-2-phosphonyl methoxypropyl) cytosine (HPMPC) (1995) (0)
Anti-varicella-zoster virus bicyclic nucleosides: Synthesis and in vitro evaluation of 2 ',3 '-dideoxy nucleoside derivatives (2002) (0)
Successful treatment of severe anogenital papillomavirus infections in AIDS patients with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (1995) (0)
between Antiherpesvirus Drugs Associations and Highlight Differences Genes Yield Novel Phenotype-Genotype Thymidine Kinase and DNA Polymerase Varicella-Zoster Virus Mutants in the-Selected Drug-Resistant In Vitro (2012) (0)
Study of the role of the complex formed by the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress (2017) (0)
Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral eva (2011) (0)
Synthesis and Antiviral Evaluation of C5-Substituted-(1,3-diyne)-2′-deoxyuridines. (2012) (0)
Synthesis and biological evaluation of novel mononuclear Ru(II) compounds as potential antiviral and cytotoxic agents (2016) (0)
Novel Aryl Substituted Bicyclic Furo Nucleosides as Extremely Potent and Selective Anti‐VZV Agents (2001) (0)
Evaluation of Novel Acyclic Nucleoside Phosphonates against Human and Animal γ-Herpesviruses (2013) (0)
Synthesis of acyclic nucleotide analogues derived from 6-(aminomethyl)purines and purine-6-carboxamidines (1996) (0)
Novel mutations in the herpes simplex virus type 1 (HSV-1) DNA polymerase associated with resistance to foscarnet (PFA) and 2-phosphonylmethoxyethyl (PME) derivatives of adenine (PMEA) and 2,6-diaminopurine (PMEDAP) (2002) (0)
Restriction endonuclease patterns of HSV-1 and HSV-2 DNA isolated from 2 patients with relapsing episodes (1992) (0)
Characterization of the DNA polymerase genes of varicella-zoster virus (VZV) resistant to foscarnet (PFA) and the 2-phosphonomethoxyethyl (PME) derivatives of adenine (Adefovir, PMEA) and 2,6-diaminopurine (PMEDAP) (2004) (0)
CD14+ Cells are Responsible for Transfer of Herpes Simplex Virus (HSV) Infection to Epithelial Cells Grown in 3-Dimensional Cultures (2008) (0)
Mode of action of CDV treatment of a primary human papillomavirus positive tumor on a secondary, untreated tumor in mice (2017) (0)
Synthesis, characterization and biological evaluation of 1,3-thiazolidine-4-ones derived from (2S)-2-benzoylamino-3-methylbutanohydrazide hydrazones (2021) (0)
Synthesis and Antiviral Activity of Imidazo[1,2-a]pyridines. (1999) (0)
Susceptibility of Human Cytomegalovirus (HCMV) Drug-resistant Viruses to a New Class of Acyclic Nucleoside Phosphonate Analogues (ANPs) (2008) (0)
Specific inhibition of Orthopoxvirus replication by small interfering RNA: involvement in the mechanism of action of ST-246 (2007) (0)
Tripartate Prodrugs of Hydroxy-containing Compounds (2011) (0)
Synthesis of a 3′-Deoxy-C -Nucleoside Phosphonate Bearing 9-Deazaadenine as Base Moiety (2018) (0)
ProTides of N-(3-(5-(2 '-deoxyuridine))prop-2-ynyl)octanamide phosphate, a potent and selective inhibitor of thymidylate synthase X from Mycobacterium tuberculosis, as potential anti-tubercular and anti-viral agents (2014) (0)
Treatment of primary tumor with cidofovir reduces tumor growth of primary and untreated secondary HPV positive tumor (2015) (0)
Keratinocyte organotypic cultures as a model for studying viral infections (2000) (0)
Novel Bicyclic Furanopyrimidines with Dual anti‐VZV and ‐HCMV Activity. (2004) (0)
Enhanced antiviral activity of hexadecyloxypropyl-PME-N-6-cyclopropyl-diaminopurine against herpesviruses, hepatitis B virus and vaccinia virus, in vitro (2007) (0)
SAR of monosubstituted phenyl furano pyrimidine as potent and selective anti Varicella-Zoster Virus (VZV) compounds (2006) (0)
Synthesis and Antiviral Activity of Carbocyclic Oxetanocin Analogues ( C‐OXT‐A, C‐OXT‐G) and Related Compounds. Part 2. (1994) (0)
SURVEY AND SUMMARY Distribution and effects of amino acid changes in drug-resistant (cid:2) and (cid:3) herpesviruses DNA polymerase (2016) (0)
Antiviral activity of different anti-herpesvirus compounds on keratinocyte organotypic cultures infected with herpes simplex virus and varicella-zoster virus (2000) (0)
Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-Naphthalenylmethyl Uracil Derivatives and Their Analogues as Probable Inhibitors of Human Cytomegalovirus Replication (2022) (0)
di fl uoro-5-phosphono-pent-2-en-1-yl nucleosides as potential antiviral agents † (2017) (0)
Synthesis and Antiviral Activity Evaluation of Some New Aminoadamantane Derivatives. Part 2. (1996) (0)
Synthesis and anti‐HIV‐1 and anti‐HCMV Activity of 1‐Substituted 3‐(3,5‐Dimethylbenzyl)uracil Derivatives. (2006) (0)
CellsVirus Reactivation in P3HR-1 Metabolism of Cyclic Prodrugs upon Gammaherpesviruses Revealed an Altered Phosphonates against Human and Animal Evaluation of Novel Acyclic Nucleoside (2014) (0)
Although the bicyclic nucleoside analogues (BCNAs) are highly active against varicella-zoster virus (VZV), they are inactive against simian varicella virus (SVV) despite efficient phosphorylation of the BCNAs by SVV-encoded thymidine kinase (2004) (0)
Effect of cidofovir on the tumor growth of SiHa (human cervical carcinoma) cells in nude mice (1997) (0)
Synthesis and Biological Activity of Some 2-Aminopurine Carbonucleosides. (1998) (0)
Design, synthesis, and biological evaluation of novel anti-VZV agents (2007) (0)
Synthesis and Antiviral Activities of 8-Alkynyl-, 8-Alkenyl-, and 8- Alkyl-2′-deoxyadenosine Analogues. (1994) (0)
New amphiphilic prodrugs of adefovir and cidofovir (2011) (0)
Skin hypoxia enhances killing of UVB-damaged keratinocytes through ROS-mediated apoptosis requiring Noxa and Bim (2011) (0)
ChemInform Abstract: Uracil Derivatives and Analogues. Part 21. Palladium-Catalyzed Synthesis of (E)-5-(2-Acylvinyl)-2′-deoxyuridines and Their Antiviral and Cytotoxic Activities. (1995) (0)
[Using antiviral drugs for Orthopoxvirus infections]. (2004) (0)
[Novel therapeutic weapons against poxviruses]. (2008) (0)
Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues. (1998) (0)
Mononuclear cells as a transfer vehicle for orthopoxvirus infection of epithelial cells grown in 3D (2010) (0)
A new family of non-nucleoside inhibitors of human cytomegalovirus (HCMV) and varicella-zoster virus (VZV) based on the beta-keto-gamma-sultone template (2005) (0)
The Twentieth International Conference on Antiviral Research (2007) (0)
Addition of an adjuvant to cidofovir treatment of primary human papillomavirus positive tumor influences untreated secondary tumor in mice (2016) (0)
Synergistic targeting of the PI3K/mTOR and MAPK/ERK pathways in Merkel cell carcinoma (2022) (0)
Design and synthesis of novel non-nucleoside anti-HCMV agents [Abstract] (2008) (0)

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