Graham C. Walker
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American biologist
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Why Is Graham C. Walker Influential?
(Suggest an Edit or Addition)According to Wikipedia, Graham Charles Walker is an American biologist, notable for his work explicating the structure and function of proteins involved in DNA repair and mutagenesis, with applications for cancer, and for understanding rhizobium functions that infect plants and mammals.
Graham C. Walker's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- DNA Repair and Mutagenesis (2006) (3369)
- Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli. (1984) (1548)
- A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance (2003) (1077)
- Mechanisms of DNA damage, repair, and mutagenesis (2017) (820)
- How rhizobial symbionts invade plants: the Sinorhizobium–Medicago model (2007) (814)
- Antibiotics induce redox-related physiological alterations as part of their lethality. (2014) (613)
- Eukaryotic Translesion Polymerases and Their Roles and Regulation in DNA Damage Tolerance (2009) (590)
- Exopolysaccharide-deficient mutants of Rhizobium meliloti that form ineffective nodules. (1985) (580)
- DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. (1980) (481)
- Succinoglycan Is Required for Initiation and Elongation of Infection Threads during Nodulation of Alfalfa byRhizobium meliloti (1998) (463)
- Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics (2012) (395)
- RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation. (1988) (394)
- Symbiotic mutants of rhizobium meliloti that uncouple plant from bacterial differentiation (1985) (337)
- Molecular determinants of a symbiotic chronic infection. (2008) (336)
- Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage. (2015) (328)
- The SOS response: recent insights into umuDC-dependent mutagenesis and DNA damage tolerance. (2000) (323)
- Site-directed insertion and deletion mutagenesis with cloned fragments in Escherichia coli (1985) (321)
- A novel exopolysaccharide can function in place of the Calcofluor-binding exopolysaccharide in nodulation of alfalfa by Rhizobium meliloti (1989) (300)
- Biosynthesis of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti (1993) (299)
- Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug (2013) (285)
- General transduction in Rhizobium meliloti (1984) (279)
- Degradation of carboxy-terminal-tagged cytoplasmic proteins by the Escherichia coli protease HflB (FtsH). (1998) (275)
- Inducibility of a gene product required for UV and chemical mutagenesis in Escherichia coli. (1981) (269)
- Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli. (1983) (266)
- A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates (2006) (248)
- Cellular defects caused by deletion of the Escherichia coli dnaK gene indicate roles for heat shock protein in normal metabolism (1989) (237)
- Escherichia coli dnaK null mutants are inviable at high temperature (1987) (234)
- Rhizobium meliloti mutants that fail to succinylate their Calcofluor-binding exopolysaccharide are defective in nodule invasion (1987) (233)
- New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis (1989) (225)
- umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. (1985) (209)
- Unraveling the physiological complexities of antibiotic lethality. (2015) (208)
- Genes needed for the modification, polymerization, export, and processing of succinoglycan by Rhizobium meliloti: a model for succinoglycan biosynthesis (1993) (206)
- Alfalfa Root Nodule Invasion Efficiency Is Dependent on Sinorhizobium melilotiPolysaccharides (2000) (200)
- Low molecular weight EPS II of Rhizobium meliloti allows nodule invasion in Medicago sativa. (1996) (199)
- Error-prone translesion synthesis mediates acquired chemoresistance (2010) (197)
- DnaK as a thermometer: threonine-199 is site of autophosphorylation and is critical for ATPase activity. (1991) (194)
- Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy (2010) (185)
- A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action (2019) (184)
- The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. (2006) (181)
- A LuxR Homolog Controls Production of Symbiotically Active Extracellular Polysaccharide II by Sinorhizobium meliloti (2002) (178)
- Managing DNA polymerases: Coordinating DNA replication, DNA repair, and DNA recombination (2001) (178)
- Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. (2009) (178)
- Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant (2008) (178)
- Exopolysaccharides of Rhizobium: synthesis, regulation and symbiotic function. (1994) (177)
- Rhizobium meliloti mutants that overproduce the R. meliloti acidic calcofluor-binding exopolysaccharide (1988) (177)
- A Rhizobium meliloti homolog of the Escherichia coli peptide-antibiotic transport protein SbmA is essential for bacteroid development. (1993) (176)
- A model for a umuDC-dependent prokaryotic DNA damage checkpoint. (1999) (173)
- Expression of the E. coli uvrA gene is inducible (1981) (173)
- Similar requirements of a plant symbiont and a mammalian pathogen for prolonged intracellular survival. (2000) (173)
- groEL and dnaK genes of Escherichia coli are induced by UV irradiation and nalidixic acid in an htpR+-dependent fashion. (1984) (172)
- Genetic analysis of a cluster of genes required for synthesis of the calcofluor-binding exopolysaccharide of Rhizobium meliloti (1988) (167)
- Detailed structural characterization of succinoglycan, the major exopolysaccharide of Rhizobium meliloti Rm1021 (1994) (166)
- BluB cannibalizes flavin to form the lower ligand of vitamin B12 (2007) (163)
- Identification of plasmid (pKM101)-coded proteins involved in mutagenesis and UV resistance (1982) (162)
- Succinoglycan Production by Rhizobium meliloti Is Regulated through the ExoS-ChvI Two-Component Regulatory System (1998) (162)
- Mutagenesis and more: umuDC and the Escherichia coli SOS response. (1998) (154)
- Altering the conserved nucleotide binding motif in the Salmonella typhimurium MutS mismatch repair protein affects both its ATPase and mismatch binding activities. (1991) (152)
- Mutations altering heat shock specific subunit of RNA polymerase suppress major cellular defects of E. coli mutants lacking the DnaK chaperone. (1990) (150)
- Chronic intracellular infection of alfalfa nodules by Sinorhizobium meliloti requires correct lipopolysaccharide core (2002) (150)
- Cloning vector system for Corynebacterium glutamicum (1985) (148)
- Y-family DNA polymerases in Escherichia coli. (2007) (146)
- Rhizobium meliloti exopolysaccharides: synthesis and symbiotic function. (1996) (141)
- Family of glycosyl transferases needed for the synthesis of succinoglycan by Rhizobium meliloti (1993) (140)
- The 32-kilobase exp gene cluster of Rhizobium meliloti directing the biosynthesis of galactoglucan: genetic organization and properties of the encoded gene products (1997) (136)
- Genetic techniques in Rhizobium meliloti. (1991) (136)
- Structure of the endonuclease domain of MutL: unlicensed to cut. (2010) (132)
- Structural Characterization of the Symbiotically Important Low-Molecular-Weight Succinoglycan ofSinorhizobium meliloti (1999) (130)
- Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation. (2013) (128)
- Conjugal transfer system of the IncN plasmid pKM101 (1985) (127)
- Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli (2013) (124)
- Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis. (1990) (124)
- Beta clamp directs localization of mismatch repair in Bacillus subtilis. (2008) (121)
- Symbiotic loci of Rhizobium meliloti identified by random TnphoA mutagenesis (1988) (121)
- UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. (2007) (119)
- Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis (2014) (117)
- Cold sensitivity induced by overproduction of UmuDC in Escherichia coli (1985) (114)
- The SOS Regulatory Network. (2008) (113)
- Delta dnaK52 mutants of Escherichia coli have defects in chromosome segregation and plasmid maintenance at normal growth temperatures (1989) (110)
- Biosynthetic control of molecular weight in the polymerization of the octasaccharide subunits of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti. (1998) (109)
- The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase. (1999) (109)
- Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing (2010) (106)
- Functional organization of plasmid pKM101 (1981) (103)
- SOS-regulated proteins in translesion DNA synthesis and mutagenesis. (1995) (103)
- Functional characterization of bacterial sRNAs using a network biology approach (2011) (100)
- Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12. (2006) (99)
- The Rhizobium meliloti exoK gene and prsD/prsE/exsH genes are components of independent degradative pathways which contribute to production of low‐molecular‐weight succinoglycan (1997) (99)
- Visualization of mismatch repair in bacterial cells. (2001) (99)
- Exogenous suppression of the symbiotic deficiencies of Rhizobium meliloti exo mutants (1992) (98)
- Structural studies of a novel exopolysaccharide produced by a mutant of Rhizobium meliloti strain Rm1021. (1990) (97)
- The Escherichia coli polB gene, which encodes DNA polymerase II, is regulated by the SOS system (1990) (97)
- Similarity to peroxisomal-membrane protein family reveals that Sinorhizobium and Brucella BacA affect lipid-A fatty acids. (2004) (96)
- Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli (2010) (95)
- Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ* (2012) (95)
- Deficiency of a Sinorhizobium meliloti bacA Mutant in Alfalfa Symbiosis Correlates with Alteration of the Cell Envelope (2002) (95)
- DnaK, hsp73, and their molten globules. Two different ways heat shock proteins respond to heat. (1992) (91)
- Y‐family DNA polymerases respond to DNA damage‐independent inhibition of replication fork progression (2006) (88)
- Construction of an Escherichia coli K-12 ada deletion by gene replacement in a recD strain reveals a second methyltransferase that repairs alkylated DNA (1988) (87)
- Rhizobium meliloti exoG and exoJ mutations affect the exoX-exoY system for modulation of exopolysaccharide production (1991) (86)
- Cell Cycle Control by the Master Regulator CtrA in Sinorhizobium meliloti (2015) (85)
- Regulation of Rhizobium meliloti exo genes in free-living cells and in planta examined by using TnphoA fusions (1991) (84)
- Rhizobial peptidase HrrP cleaves host-encoded signaling peptides and mediates symbiotic compatibility (2015) (83)
- BacA, an ABC Transporter Involved in Maintenance of Chronic Murine Infections with Mycobacterium tuberculosis (2008) (82)
- Importance of unusually modified lipid A in Sinorhizobium stress resistance and legume symbiosis (2005) (80)
- Isolation and characterization of mutants of the plasmid pKM101 deficient in their ability to enhance mutagenesis and repair (1978) (80)
- Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. (2010) (79)
- Genetic analysis of the Rhizobium meliloti bacA gene: functional interchangeability with the Escherichia coli sbmA gene and phenotypes of mutants (1997) (78)
- A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq (2011) (78)
- groE mutants of Escherichia coli are defective in umuDC-dependent UV mutagenesis (1989) (77)
- Striking Complexity of Lipopolysaccharide Defects in a Collection of Sinorhizobium meliloti Mutants (2003) (76)
- The muc genes of pKM101 are induced by DNA damage (1983) (75)
- Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis (1997) (75)
- The exoR gene of Rhizobium meliloti affects RNA levels of other exo genes but lacks homology to known transcriptional regulators (1991) (75)
- Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products (2008) (74)
- Essential Role for the BacA Protein in the Uptake of a Truncated Eukaryotic Peptide in Sinorhizobium meliloti (2008) (74)
- Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae (1988) (73)
- Exo-Oligosaccharides of Rhizobium sp. Strain NGR234 Are Required for Symbiosis with Various Legumes (2006) (72)
- DnaK mutants defective in ATPase activity are defective in negative regulation of the heat shock response: expression of mutant DnaK proteins results in filamentation (1994) (72)
- Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis (2014) (71)
- Induction and autoregulation of ada, a positively acting element regulating the response of Escherichia coli K-12 to methylating agents (1985) (70)
- Disruption of sitA Compromises Sinorhizobium meliloti for Manganese Uptake Required for Protection against Oxidative Stress (2006) (70)
- Mutations affecting regulation of methionine biosynthetic genes isolated by use of met-lac fusions (1982) (69)
- Global analysis of cell cycle gene expression of the legume symbiont Sinorhizobium meliloti (2014) (69)
- Comparison of Responses to Double-Strand Breaks between Escherichia coli and Bacillus subtilis Reveals Different Requirements for SOS Induction (2008) (69)
- TtsI regulates symbiotic genes in Rhizobium species NGR234 by binding to tts boxes (2008) (69)
- NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η. (2012) (69)
- Multifaceted Recognition of Vertebrate Rev1 by Translesion Polymerases ζ and κ* (2012) (68)
- Transcriptional Modulator NusA Interacts with Translesion DNA Polymerases in Escherichia coli (2008) (67)
- The Transcription Elongation Factor NusA Is Required for Stress-Induced Mutagenesis in Escherichia coli (2009) (67)
- Novel Role for the C Terminus of Saccharomyces cerevisiae Rev1 in Mediating Protein-Protein Interactions (2006) (66)
- T4-induced RNA ligase joins single-stranded oligoribonucleotides. (1975) (64)
- The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti (2013) (64)
- DNA Polymerase V Allows Bypass of Toxic Guanine Oxidation Products in Vivo* (2007) (63)
- Isolation and characterization of Tn5 insertion mutations in the lexA gene of Escherichia coli (1983) (63)
- A Novel Screening Method for Isolating Exopolysaccharide-Deficient Mutants (1998) (62)
- umuDC-Mediated Cold Sensitivity Is a Manifestation of Functions of the UmuD2C Complex Involved in a DNA Damage Checkpoint Control (2001) (60)
- Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? (2017) (58)
- The acetyl substituent of succinoglycan is not necessary for alfalfa nodule invasion by Rhizobium meliloti Rm1021 (1993) (58)
- Characterization of Escherichia coli translesion synthesis polymerases and their accessory factors. (2006) (57)
- Replication is required for the RecA localization response to DNA damage in Bacillus subtilis (2007) (57)
- Inducible reactivation and mutagenesis of UV-irradiated bacteriophage P22 in Salmonella typhimurium LT2 containing the plasmid pKM101 (1978) (57)
- CbrA Is a Stationary-Phase Regulator of Cell Surface Physiology and Legume Symbiosis in Sinorhizobium meliloti (2006) (56)
- Regulation of damage-inducible genes in Escherichia coli. (1982) (56)
- The Highly Conserved Bacterial RNase YbeY Is Essential in Vibrio cholerae, Playing a Critical Role in Virulence, Stress Regulation, and RNA Processing (2014) (55)
- The Rhizobium meliloti ExoK and ExsH glycanases specifically depolymerize nascent succinoglycan chains. (1998) (54)
- The phbC (poly-beta-hydroxybutyrate synthase) gene of Rhizobium (Sinorhizobium) meliloti and characterization of phbC mutants. (1998) (54)
- Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD′2C) (2001) (53)
- Clp and Lon Proteases Occupy Distinct Subcellular Positions in Bacillus subtilis (2008) (53)
- Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host. (2010) (53)
- Proteomic Alterations Explain Phenotypic Changes in Sinorhizobium meliloti Lacking the RNA Chaperone Hfq (2010) (53)
- Resistance to alkylation damage in Escherichia coli: role of the Ada protein in induction of the adaptive response. (1990) (52)
- The SOS Regulatory Network. (2008) (52)
- Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria (2014) (52)
- Identification of specific amino acid residues in the E. coli beta processivity clamp involved in interactions with DNA polymerase III, UmuD and UmuD'. (2004) (52)
- NMR studies of succinoglycan repeating-unit octasaccharides from Rhizobium meliloti and Agrobacterium radiobacter. (1995) (51)
- ATPase-Defective Derivatives of Escherichia coliDnaK That Behave Differently with Respect to ATP-Induced Conformational Change and Peptide Release (2001) (51)
- Coexpression of UmuD' with UmuC suppresses the UV mutagenesis deficiency of groE mutants (1992) (51)
- Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance. (2008) (51)
- The Symbiosis Regulator CbrA Modulates a Complex Regulatory Network Affecting the Flagellar Apparatus and Cell Envelope Proteins (2007) (51)
- Genetic Analysis of the Mobilization and Leading Regions of the IncN plasmids pKM101 and pCU1 (1999) (50)
- The exoD gene of Rhizobium meliloti encodes a novel function needed for alfalfa nodule invasion (1991) (50)
- Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2 (1985) (50)
- Identification of Novel Sinorhizobium meliloti Mutants Compromised for Oxidative Stress Protection and Symbiosis (2006) (50)
- Biological Cost of Pyocin Production during the SOS Response in Pseudomonas aeruginosa (2014) (49)
- The DNA Polymerase Activity of Saccharomyces cerevisiae Rev1 is Biologically Significant (2011) (48)
- Genetic Analysis of the Sinorhizobium meliloti BacA Protein: Differential Effects of Mutations on Phenotypes (2001) (48)
- Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the β processivity clamp (2002) (48)
- The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents. (1994) (48)
- Localization of UvrA and Effect of DNA Damage on the Chromosome of Bacillus subtilis (2002) (48)
- Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis. (2016) (48)
- A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase (2009) (47)
- The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesis (1996) (47)
- Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts. (2008) (47)
- Phasmid vectors for identification of genes by complementation of Escherichia coli mutants (1985) (47)
- The Succinyl and Acetyl Modifications of Succinoglycan Influence Susceptibility of Succinoglycan to Cleavage by the Rhizobium meliloti Glycanases ExoK and ExsH (1998) (47)
- Immunogold localization of the DnaK heat shock protein in Escherichia coli cells. (1993) (46)
- Genetic analyses of DNA repair: inference and extrapolation. (1985) (46)
- Identification of YbeY-Protein Interactions Involved in 16S rRNA Maturation and Stress Regulation in Escherichia coli (2016) (46)
- Two processivity clamp interactions differentially alter the dual activities of UmuC (2006) (45)
- Mutagenesis, by methylating and ethylating agents, in mutH, mutL, mutS, and uvrD mutants of Salmonella typhimurium LT2 (1983) (45)
- Sinorhizobium meliloti CpdR1 is critical for co‐ordinating cell cycle progression and the symbiotic chronic infection (2009) (45)
- Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex (2018) (44)
- Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction. (2017) (43)
- Interrelations between Glycine Betaine Catabolism and Methionine Biosynthesis in Sinorhizobium meliloti Strain 102F34 (2006) (42)
- Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa. (2012) (42)
- Robustness encoded across essential and accessory replicons of the ecologically versatile bacterium Sinorhizobium meliloti (2018) (41)
- A monocysteine approach for probing the structure and interactions of the UmuD protein (1994) (41)
- Genetic Interactions between the Escherichia coli umuDC Gene Products and the β Processivity Clamp of the Replicative DNA Polymerase (2001) (41)
- Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach (1996) (39)
- A Role for the umuDC Gene Products ofEscherichia coli in Increasing Resistance to DNA Damage in Stationary Phase by Inhibiting the Transition to Exponential Growth (2000) (39)
- A model for the structure of the Escherichia coli SOS-regulated UmuD2 protein. (2002) (39)
- Effect of o-acyl substituents on the functional behaviour of Rhizobium meliloti succinoglycan. (1997) (38)
- A Novel Sinorhizobium meliloti Operon Encodes an α-Glucosidase and a Periplasmic-Binding-Protein-Dependent Transport System for α-Glucosides (1999) (38)
- A Highly Conserved Protein of Unknown Function Is Required by Sinorhizobium meliloti for Symbiosis and Environmental Stress Protection (2007) (38)
- Rhizobium meliloti mutants unable to synthesize anthranilate display a novel symbiotic phenotype (1992) (37)
- Seeking a niche: putative contributions of the hfq and bacA gene products to the successful adaptation of the brucellae to their intracellular home. (2002) (37)
- Spontaneous mutators of salmonella typhimurium LT2 generated by insertion of transposable elements (1981) (37)
- Identification of pKM101-encoded loci specifying potentially lethal gene products (1985) (37)
- The Sinorhizobium meliloti RNA Chaperone Hfq Mediates Symbiosis of S. meliloti and Alfalfa (2010) (35)
- Role of BacA in Lipopolysaccharide Synthesis, Peptide Transport, and Nodulation by Rhizobium sp. Strain NGR234 (2011) (35)
- Nucleotide sequence of the Salmonella typhimurium mutL gene required for mismatch repair: homology of MutL to HexB of Streptococcus pneumoniae and to PMS1 of the yeast Saccharomyces cerevisiae (1989) (35)
- Plasmid (pKM101)-mediated enhancement of repair and mutagenesis: Dependence on chromosomal genes in Escherichia coli K-12 (1977) (35)
- umuDC-dnaQ Interaction and Its Implications for Cell Cycle Regulation and SOS Mutagenesis inEscherichia coli (2001) (34)
- Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101 (1979) (34)
- Characterization of an endonuclease associated with the drug resistance plasmid pKM101 (1977) (34)
- New phenotypes associated with mucAB: alteration of a MucA sequence homologous to the LexA cleavage site (1987) (33)
- A Non-cleavable UmuD Variant That Acts as a UmuD′ Mimic* (2006) (33)
- PMR or the self-complementary oligoribonucleotide CpCpGpG. (1974) (32)
- Mutations Affecting the Ability of theEscherichia coli UmuD′ Protein To Participate in SOS Mutagenesis (1999) (32)
- Proficient and Accurate Bypass of Persistent DNA Lesions by DinB DNA Polymerases (2007) (32)
- Interactions of Escherichia coli UmuD with activated RecA analyzed by cross-linking UmuD monocysteine derivatives (1996) (32)
- Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247 (2016) (31)
- Analysis of mRNA synthesis following induction of the Escherichia coli SOS system. (1984) (30)
- The Type IV Secretion System of Sinorhizobium meliloti Strain 1021 Is Required for Conjugation but Not for Intracellular Symbiosis (2006) (30)
- Host-dependent transposon Tn5-mediated streptomycin resistance (1984) (29)
- Genetic and Biochemical Characterization of a NovelumuD Mutation: Insights into a Mechanism for UmuD Self-Cleavage (2001) (29)
- Brucella abortus bacA mutant induces greater pro-inflammatory cytokines than the wild-type parent strain. (2007) (29)
- Multiple Ku orthologues mediate DNA non‐homologous end‐joining in the free‐living form and during chronic infection of Sinorhizobium meliloti (2007) (29)
- Incomplete base excision repair contributes to cell death from antibiotics and other stresses. (2018) (29)
- Skiing the black diamond slope: progress on the biochemistry of translesion DNA synthesis. (1998) (28)
- Important Late-Stage Symbiotic Role of the Sinorhizobium meliloti Exopolysaccharide Succinoglycan (2018) (28)
- Pseudo-B12 Joins the Cofactor Family (2007) (28)
- New mutations in cloned Escherichia coli umuDC genes: novel phenotypes of strains carrying a umuC125 plasmid. (1991) (28)
- Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality (2017) (28)
- Anaerobiosis induces expression of ant, a new Escherichia coli locus with a role in anaerobic electron transport (1984) (27)
- Mud(Ap, lac)-generated fusions in studies of gene expression. (1983) (27)
- Fertility inhibition of RP1 by IncN plasmid pKM101 (1985) (27)
- Inferences Concerning the ATPase Properties of DnaK and Other HSP70s Are Affected by the ADP Kinase Activity of Copurifying Nucleoside-diphosphate Kinase* (1999) (27)
- Plasmid (pKM101)-mediated Weigle reactivation in Escherichia coli K12 and Salmonella typhimurium LT2: genetic dependence, kinetics of induction, and effect of chloramphenicol. (1980) (26)
- Entry exclusion determinant(s) of IncN plasmid pKM101 (1985) (26)
- A region of the Ada DNA-repair protein required for the activation of ada transcription is not necessary for activation of alkA. (1991) (25)
- New discoveries linking transcription to DNA repair and damage tolerance pathways (2011) (25)
- Citrate Synthase Mutants of Sinorhizobium meliloti Are Ineffective and Have Altered Cell Surface Polysaccharides (1999) (25)
- The Salmonella typhimurium LT2 uvrD gene is regulated by the lexA gene product (1983) (24)
- LexA-independent expression of a mutant mucAB operon (1990) (24)
- Genetic manipulations in Rhizobium meliloti utilizing two new transposon Tn5 derivatives (1986) (24)
- Defect in expression of heat-shock proteins at high temperature in xthA mutants (1986) (23)
- All nod genes of Rhizobium meliloti are involved in alfalfa nodulation by exo mutants (1988) (23)
- Genetic analysis of Rhizobium meliloti bacA-phoA fusion results in identification of degP: two loci required for symbiosis are closely linked to degP (1996) (23)
- Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1. (2011) (23)
- Responses of the model legume Medicago truncatula to the rhizobial exopolysaccharide succinoglycan (2008) (22)
- Rhizobium meliloti exopolysaccharides: genetic analyses and symbiotic importance. (1991) (22)
- A directional, high-frequency chromosomal mobilization system for genetic mapping of Rhizobium meliloti (1992) (22)
- BacA-Mediated Bleomycin Sensitivity in Sinorhizobium meliloti Is Independent of the Unusual Lipid A Modification (2006) (22)
- Differential cleavage of LexA and UmuD mediated by recA Pro67 mutants: implications for common LexA and UmuD binding sites on RecA. (1998) (21)
- UmuD2 Inhibits a Non-covalent Step during DinB-mediated Template Slippage on Homopolymeric Nucleotide Runs* (2010) (21)
- 2,4,6-Trisubstituted pyridines. Synthesis, fluorescence, and scintillator properties (1973) (21)
- Localization of the plasmid (pKM101) gene(s) involved in recA+lexA+-dependent mutagenesis (2004) (21)
- Acidic conditions permit effective nodulation of alfalfa by invasion-deficient Rhizobium meliloti exoD mutants. (1991) (21)
- Characterization of Novel Alleles of the Escherichia coli umuDC Genes Identifies Additional Interaction Sites of UmuC with the Beta Clamp (2009) (20)
- Regulation and functions of Escherichia coli genes induced by DNA damage. (1982) (20)
- Hydroxylamine reductase from Pseudomonas aeruginosa. (1961) (20)
- The mode of incorporation of 6-benzylaminopurine into tobacco callus transfer ribonucleic Acid: a double labeling determination. (1974) (20)
- Identification of the uvrD gene product of Salmonella typhimurium LT2 (1983) (19)
- Alteration of the carboxyl-terminal domain of Ada protein influences its inducibility, specificity, and strength as a transcriptional activator (1988) (19)
- Glucose 6-phosphate dehydrogenase is required for sucrose and trehalose to be efficient osmoprotectants in Sinorhizobium meliloti. (2003) (19)
- Enteric YaiW Is a Surface-Exposed Outer Membrane Lipoprotein That Affects Sensitivity to an Antimicrobial Peptide (2013) (19)
- Steric Gate Variants of UmuC Confer UV Hypersensitivity on Escherichia coli (2008) (18)
- Mutational analysis of the RecA protein L1 region identifies this area as a probable part of the co‐protease substrate binding site (1997) (18)
- Different Phenotypic Classes of Sinorhizobium meliloti Mutants Defective in Synthesis of K Antigen (1998) (18)
- Mutagenesis and other responses induced by DNA damage in Escherichia coli. (1982) (18)
- Genetic mapping of symbiotic loci on the Rhizobium meliloti chromosome. (1992) (18)
- The mutH, mutL, mutS, and uvrD genes of Salmonella typhimurium LT2. (1984) (18)
- Active site residues critical for flavin binding and 5,6‐dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB (2012) (18)
- Elevated Levels of Era GTPase Improve Growth, 16S rRNA Processing, and 70S Ribosome Assembly of Escherichia coli Lacking Highly Conserved Multifunctional YbeY Endoribonuclease (2018) (18)
- The Sinorhizobium meliloti sensor histidine kinase CbrA contributes to free-living cell cycle regulation. (2013) (18)
- A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a periplasmic-binding-protein-dependent transport system for alpha-glucosides. (1999) (18)
- Genetic analyses of Rhizobium meliloti exopolysaccharides. (1990) (18)
- 3-Substituted adenines. In vitro enzyme inhibition and antiviral activity. (1979) (17)
- Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides (2021) (17)
- Restriction endonuclease cleavage map of pKM101: Relationship to parental plasmid R46 (2004) (17)
- Structural Basis of Rev 1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev 1 , Heterodimeric Polymerase ( Pol ) (2012) (16)
- Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer (2020) (16)
- REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks (2020) (16)
- Complementation of a pKM101 derivative that decreases resistance to UV killing but increases susceptibility to mutagenesis. (1985) (15)
- Mutagenesis- and repair-enhancing activities associated with the plasmid pKM101. (1979) (15)
- Comparison of cytokinin activities of the base, ribonucleoside and 5′- and cyclic-3′,5′-monophosphate ribonucleotides of N6-isopentenyl-, N6-benzyl or 8-bromo-adenine (1975) (15)
- Stepwise enzymatic oligoribonucleotide synthesis including modified nucleotides. (1975) (15)
- Inhibition of RecA-mediated cleavage in covalent dimers of UmuD (1996) (14)
- C21orf57 is a human homologue of bacterial YbeY proteins. (2017) (14)
- A Chemical Genetics Analysis of the Roles of Bypass Polymerase DinB and DNA Repair Protein AlkB in Processing N 2-Alkylguanine Lesions In Vivo (2014) (13)
- Genetic localization and characterization of a pKM101-coded endonuclease (1983) (12)
- Understanding the complexity of an organism's responses to DNA damage. (2000) (12)
- Endoribonuclease YbeY Is Linked to Proper Cellular Morphology and Virulence in Brucella abortus (2018) (12)
- The unusual UBZ domain of Saccharomyces cerevisiae polymerase η. (2010) (12)
- Nitrite reductase from Pseudomonas aeruginosa. (1961) (11)
- Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality. (2021) (11)
- Analyses of the Roles of R.Meliloti Exopolysaccharides in Nodulation (1991) (11)
- The SOS response and induced mutagenesis. (1990) (11)
- Regulation and function of cellular gene products involved in UV and chemical mutagenesis in E. coli. (1983) (11)
- Molecular Principles Underlying the Ames Salmonella/Microsome Test: Elements and Design of Short-Term Mutagenesis Tests (1983) (11)
- Virtual Pharmacophore Screening Identifies Small‐Molecule Inhibitors of the Rev1‐CT/RIR Protein–Protein Interaction (2019) (10)
- The effects of the ultraviolet-protecting plasmids pKM101 and R205 on DNA polymerase I activity in Escherichia coli K-12. (1979) (10)
- Interactions of peptides with DnaK and C-terminal DnaK fragments studied using fluorescent and radioactive peptides. (1998) (10)
- Identification of the Rhizobium meliloti alcohol dehydrogenase gene (adhA) and heterologous expression in Alcaligenes eutrophus. (1998) (10)
- Sinorhizobium meliloti YbeY is a zinc-dependent single-strand specific endoribonuclease that plays an important role in 16S ribosomal RNA processing (2019) (9)
- Amino acid similarities to other proteins offer insights into roles of UmuD and UmuC in mutagenesis. (1989) (9)
- To cleave or not to cleave? Insights from the LexA crystal structure. (2001) (9)
- Rhizobium meliloti Exopolysaccharides (1991) (8)
- Identification of Elements of the Peptide Binding Site of DnaK by Peptide Cross-linking* (1996) (8)
- Lack of Effect on Recombination of Mutagenesis-enhancing Plasmids in Escherichia coliK12 and Salmonella typhimuriumLT2 (1978) (8)
- Mutagenesis and cellular responses to DNA damage. (1982) (7)
- Alteration of lysine 178 in the hinge region of the Escherichia coli ada protein interferes with activation of ada, but not alkA, transcription (1995) (7)
- A constitutive O6-methylguanine-DNA methyltransferase of Rhizobium meliloti. (1990) (7)
- Signal Transduction in the Escherichia coli SOS Response (2010) (7)
- Robustness encoded across essential and accessory replicons in an ecologically versatile bacterium (2017) (7)
- Mutagenesis-enhancement by plasmids in mutagenesis tester strains. (1985) (7)
- umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. 1985. (2005) (7)
- Exopolysaccharides and RhizobiumMeliloti-Alfalfa Interactions (1993) (6)
- DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. 1980. (2005) (6)
- The groE gene products of Escherichia coli are dispensable for mucA+B(+)-dependent UV mutagenesis. (1994) (6)
- P-azidoiodoacetanilide, a new short photocrosslinker that has greater cysteine specificity than p-azidophenacyl bromide and p-azidobromoacetanilide. (1995) (5)
- Bryn Bridges and mutagenesis: exploring the intellectual space. (2001) (5)
- Genetic strategies in strain design for fermentations. (1983) (5)
- Efficient Extension of Slipped DNA Intermediates by DinB Is Required To Escape Primer Template Realignment by DnaQ (2011) (5)
- SnapShot: DNA Polymerases II Mammals (2010) (5)
- Cellular responses to DNA damage. (1985) (5)
- Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair (2022) (5)
- A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis (2020) (4)
- A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria (2022) (4)
- Biotin labeling of the symbiotically important succinoglycan oligosaccharides of Rhizobium meliloti for identification of putative plant receptors. (2001) (4)
- Identification of small molecule translesion synthesis inhibitors that target the Rev 1-CT / RIR protein-protein interaction (2018) (4)
- SnapShot: DNA Polymerases I Prokaryotes (2010) (4)
- The Centennial before the Millennium: theJournal of Bacteriology as a World Voice for Microbiological Research (1999) (4)
- Lighting torches in the DNA repair field: development of key concepts. (2005) (3)
- Genome-Wide Sensitivity Analysis of the Microsymbiont (2017) (3)
- Nucleotide Sequence oftheSalmonella typhimurium mutLGene Required forMismatch Repair: Homology ofMutLtoHexBof Streptococcus pneumoniae andtoPMS1oftheYeast (1989) (3)
- Mutagenic DNA repair in bacteria: the role of UmuDC and MucAB. (1986) (3)
- Genetic analyses of cellular functions required for UV mutagenesis in Escherichia coli. (1990) (3)
- Identification ofpKM101-Encoded LociSpecifying Potentially Lethal GeneProducts (1985) (2)
- Isolation and characterization of mutants of the plasmid pKM101 deficient in their ability to enhance mutagenesis and repair. [uv radiation, Salmonella typhimurium] (1978) (2)
- Genetic Analyses and Manipulations of Rhizobium meliloti Exopolysaccharides (1990) (2)
- Characterization of Mutants from Rhizobium Sp. Ngr234 with Defective Exopolysaccharide Synthesis (2005) (2)
- General principles of DNA repair in microorganisms and implications for future research. (1989) (2)
- Non mutagenic and mutagenic DNA damage tolerance (2016) (2)
- Symbiotic Mutants of Rhizobium Meliloti Which Produce Non-Succinylated Exopolysaccharide (1987) (2)
- Interaction between the Rev 1 C-Terminal Domain and the PolD 3 Subunit of Pol Suggests a Mechanism of Polymerase Exchange upon Rev 1 / Pol-Dependent (2016) (2)
- DnaK , hsp 73 , and Their Molten Globules (2001) (2)
- Genetic analyses of the roles of umuDC and mucAB in mutagenesis. (1986) (2)
- LexA Regulatory System (2004) (1)
- Antimutagenic effect of umuD mutant plasmids: isolation and characterization of umuD mutants reduced in their ability to promote UV mutagenesis in Escherichia coli. (1990) (1)
- Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria (2014) (1)
- Alteration of the Cell Envelope Mutant in Alfalfa Symbiosis Correlates with Sinorhizobium meliloti bacA Deficiency of a (2002) (1)
- GUEST COMMENTARY Pseudo-B 12 Joins the Cofactor Family (2008) (1)
- properties of the encoded gene products. galactoglucan: genetic organization and meliloti directing the biosynthesis of The 32-kilobase exp gene cluster of Rhizobium (2013) (1)
- Abstract 1955: Simultaneous delivery of siRNA and cisplatin by polymer-lipid hybrid nanoparticles sensitizes resistant cancer to chemotherapy (2012) (1)
- Y-family DNA polymerases in Escherichia coli Citation (2007) (1)
- A-1000 Understanding the Mechanism of Action of Anti-microbial Peptides Using a Novel DNA-based Strategy and Enantiomers (2019) (0)
- SOLUTION STRUCTURE OF THE UMUD' HOMODIMER (2001) (0)
- DOMAIN 5 RESPONDING TO THE ENVIRONMENT The SOS Regulatory Network (2013) (0)
- Genetic Localization andCharacterization ofapKM101- CodedEndonuclease (1983) (0)
- aeruginosathe SOS Response in Pseudomonas Biological Cost of Pyocin Production (2014) (0)
- Coexpression ofUmuD'withUmuC Suppresses theUV Mutagenesis Deficiency ofgroEMutants (1992) (0)
- Foti Bactericidal Antibiotics Oxidation of the Guanine Nucleotide Pool Underlies Cell Death (2012) (0)
- Additions and Corrections - 2,4,6-Trisubstituted Pyridines. Synthesis, Fluorescence, and Scintillator Properties. (1974) (0)
- A study of the antagonism exhibited by Pseudomonas aeruginosa and Pseudomonas fluorescens towards certain fungus pathogens. I Preliminary screening. Part II. (1957) (0)
- Themuc GenesofpKM101AreInduced byDNA Damage (1983) (0)
- NOTES Identification of Novel Sinorhizobium meliloti Mutants Compromised for Oxidative Stress Protection and Symbiosis (cid:1) (2007) (0)
- What is the Molecular Mechanism of UV Mutagenesis in Escherichia coli (1991) (0)
- Final report [DNA Repair and Mutagenesis - 1999] (2001) (0)
- A Single‐Molecule Reconstitution of Translesion Synthesis and Competition Between DNA Polymerases (2015) (0)
- Pseudo-B 12 Joins the Cofactor Family (cid:1) (2008) (0)
- CHAPTER 299 – Signal Transduction in the Escherichia coli SOS Response (2003) (0)
- Analysis of the Rhizobium meliloti Baca Protein: Implications for Host-Microbe Interactions (1998) (0)
- BluB bound to oxidized FMN (2007) (0)
- A Chemical Genetics Analysis of the Roles of Bypass Polymerase DinB and DNA Repair Protein AlkB in Processing N[superscript 2]-Alkylguanine Lesions In Vivo (2014) (0)
- A WhiteBox Machine Learning Approach for Revealing Antibiotic Mechanisms of Action Graphical (2019) (0)
- TheModeofIncorporation of6-Benzylaminopurine (1974) (0)
- Role of Exopolysaccharides in Nodule Invasion by Rhizobium meliloti (1998) (0)
- A Mutant Era GTPase Suppresses Phenotypes Caused by Loss of Highly Conserved YbeY Protein in Escherichia coli (2022) (0)
- Brief Reports on All Topics (1981) (0)
- (din gene/recA/lexA regulation/operon fusion/SOS functions/uvrA) (0)
- mutL, mutS, and uvrD Mutants of Salmonella typhimurium (0)
- Bactericidal Antibiotics In duce Toxic Metabolic Perturbations that Lead to Cellular Damage Graphical Abstract Highlights (2015) (0)
- Abstract 5616: Enhancing tumor cell response to chemotherapy by simultaneous delivery of siRNA and cisplatin using polymeric nanoparticles. (2013) (0)
- Solution Structure of the human Polymerase iota UBM2-Ubiquitin Complex (2010) (0)
- Abstract 4590: Cisplatin-RNAi nanotherapeutics for synergistic anti-tumor activity (2014) (0)
- Genetic Analyses Suggesting Bacterial-Plant Signalling During Nodulation (1989) (0)
- Active site mutations in the Y family DNA polymerase UmuC cause hypersensitivity to UV light and are dominant negative (2007) (0)
- Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ (2022) (0)
- Surface Exposed Outer Membrane Lipoprotein that Affects Sensitivity to 1 an Antimicrobial Peptide 2 (2013) (0)
- Some Features of Base Pair Mismatch and Heterology Escherichia coli Repair in (2003) (0)
- BluB bound to flavin anion (charge transfer complex) (2007) (0)
- Symbiotic LociofRhizobium meliloti Identified by RandomTnphoAMutagenesis (1988) (0)
- 3-SUBSTITUTED ADENINES. IN VITRO ENZYME INHIBITION AND ANTIVIRAL ACTIVITY (1979) (0)
- Identification oftheuvrDGeneProduct ofSalmonella typhimurium LT2 (1983) (0)
- REGULATION AND FUNCTIONS OF Escherichia coli GENES (1982) (0)
- 2,4,6-TRISUBSTITUTED PYRIDINES, SYNTHESIS, FLUORESCENCE, AND SCINTILLATOR PROPERTIES (1973) (0)
- Nodule invasion and intracellular survival by Sinorhizobium meliloti. (2002) (0)
- an Antimicrobial Peptide 2 (2013) (0)
- TheAcetyl Substituent ofSuccinoglycan IsNotNecessary forAlfalfa NoduleInvasion byRhizobium meliloti RmlO21 (1993) (0)
- E. coli Mutants Lacking the dnaK Heat Shock Gene: Identification of Cellular Defects and Analysis of Suppressor Mutations (1991) (0)
- Family ofGlycosyl Transferases NeededfortheSynthesis of Succinoglycan byRhizobium meliloti (1993) (0)
- cellular morphology and virulence in 1 Brucella abortus 2 3 4 (2018) (0)
- Responses of E. coli to DNA Damage and Stress (1992) (0)
- Running head: DNA polymerase activity of Rev1 in vivo Key words: Rev1, translesion synthesis, Mms2, DNA damage tolerance (2010) (0)
- Solution Structure of the Ubiquitin-Binding Motif of Human Polymerase Iota (2010) (0)
- Invasion of Alfalfa Root Nodules by the Nitrogen-Fixing Bacterium Rhizobium meliloti (2000) (0)
- BluB bound to reduced flavin (FMNH2) and molecular oxygen. (clear crystal form) (2007) (0)
- Enhancing Tumor Cell Response to Chemotherapy by Simultaneous Delivery of siRNA and Anticancer Drug Using Nanoparticles (2013) (0)
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