Greg Lemke
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Developmental Biology
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Biology
Greg Lemke's Degrees
- PhD Biochemistry Stanford University
- Bachelors Chemistry University of California, Berkeley
Why Is Greg Lemke Influential?
(Suggest an Edit or Addition)Greg Lemke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neuregulin 1 and susceptibility to schizophrenia. (2002) (1657)
- Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor (1995) (1131)
- TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response (2007) (904)
- Immunobiology of the TAM receptors (2008) (718)
- The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases (1995) (704)
- Homeostatic Regulation of the Immune System by Receptor Tyrosine Kinases of the Tyro 3 Family (2001) (676)
- Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin (1985) (538)
- An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. (1997) (514)
- Mouse P 0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons (1992) (491)
- Tyro-3 family receptors are essential regulators of mammalian spermatogenesis (1999) (485)
- An extended family of protein-tyrosine kinase genes differentially expressed in the vertebrate nervous system (1991) (413)
- Biology of the TAM receptors. (2013) (411)
- The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry. (2012) (403)
- TAM receptors regulate multiple features of microglial physiology (2016) (373)
- Notch2: a second mammalian Notch gene. (1992) (370)
- A homolog of Drosophila Notch expressed during mammalian development. (1991) (353)
- Macrophages and Dendritic Cells Use Different Axl/Mertk/Tyro3 Receptors in Clearance of Apoptotic Cells1 (2007) (349)
- Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. (1988) (348)
- Unified Nomenclature for Eph Family Receptors and Their Ligands, the Ephrins (1997) (343)
- Topographic Mapping from the Retina to the Midbrain Is Controlled by Relative but Not Absolute Levels of EphA Receptor Signaling (2000) (336)
- Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. (1996) (334)
- SCIP: A glial POU domain gene regulated by cyclic AMP (1989) (294)
- Isolation and analysis of the gene encoding peripheral myelin protein zero (1988) (276)
- Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy. (2005) (263)
- The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism (2001) (252)
- Twist mediates suppression of inflammation by type I IFNs and Axl (2006) (249)
- Neuregulins in Development (1996) (245)
- Identification and purification of glial growth factor (1984) (245)
- Cell death in the Schwann cell lineage and its regulation by neuregulin. (1996) (244)
- Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells (1988) (240)
- Unwrapping the genes of myelin (1988) (238)
- TAM receptor function in the retinal pigment epithelium (2006) (237)
- A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart (2020) (221)
- Expression and activity of the POU transcription factor SCIP. (1990) (220)
- Diversification of TAM receptor function (2014) (210)
- Purification and preliminary characterization of a glial growth factor from the bovine pituitary. (1980) (205)
- TAM receptors and the clearance of apoptotic cells (2010) (202)
- The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation (1996) (202)
- Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities (2014) (198)
- Axon‐regulated expression of a Schwann cell transcript that is homologous to a ‘growth arrest‐specific’ gene. (1991) (193)
- Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy. (2003) (186)
- Enveloped viruses disable innate immune responses in dendritic cells by direct activation of TAM receptors. (2013) (181)
- TAM receptor signaling and autoimmune disease. (2010) (179)
- Local regulation of fat metabolism in peripheral nerves. (2003) (178)
- Progesterone Stimulates the Activity of the Promoters of Peripheral Myelin Protein‐22 and Protein Zero Genes in Schwann Cells (1998) (175)
- How macrophages deal with death (2019) (170)
- Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase. (1994) (167)
- Macrophage regulation by Tyro 3 family receptors. (2003) (167)
- Schwann cell differentiation. (1996) (162)
- Axons regulate Schwann cell expression of the POU transcription factor SCIP (1994) (159)
- Glial control of neuronal development. (2001) (156)
- Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome (2020) (154)
- Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis. (2009) (149)
- The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. (1999) (148)
- T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response. (2013) (146)
- Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases (2006) (145)
- Induction of Postnatal Schwann Cell Death by the Low-Affinity Neurotrophin Receptor In Vitro and after Axotomy (2000) (144)
- Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation (2015) (141)
- Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells. (1999) (138)
- The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. (2002) (132)
- Vax genes ventralize the embryonic eye. (2005) (129)
- A relative signalling model for the formation of a topographic neural map (2004) (129)
- Microglia use TAM receptors to detect and engulf amyloid beta plaques (2021) (127)
- Cell‐specific cyclic AMP‐mediated induction of the PDGF receptor. (1990) (126)
- Genetic Dissection of TAM Receptor-Ligand Interaction in Retinal Pigment Epithelial Cell Phagocytosis (2012) (126)
- Neuregulins and neuregulin receptors in neural development (1997) (118)
- Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro. (1992) (115)
- The molecular genetics of myelination: An update (1993) (115)
- Retinotectal mapping: new insights from molecular genetics. (2005) (113)
- P0 promoter directs expression of reporter and toxin genes to schwann cells of transgenic mice (1992) (110)
- Repression of the myelin P0 gene by the POU transcription factor SCIP (1993) (108)
- The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity (2015) (106)
- A Role for Insulin-Like Growth Factor-I in the Regulation of Schwann Cell Survival (1999) (105)
- Gas6/Axl Signaling Activates the Phosphatidylinositol 3-Kinase/Akt1 Survival Pathway to Protect Oligodendrocytes from Tumor Necrosis Factorα-Induced Apoptosis (2006) (105)
- Segregation of Axial Motor and Sensory Pathways via Heterotypic Trans-Axonal Signaling (2008) (102)
- Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis (2012) (102)
- Microglia states and nomenclature: A field at its crossroads (2022) (99)
- Retinal Input Instructs Alignment of Visual Topographic Maps (2009) (97)
- Role of Gas6 in erythropoiesis and anemia in mice. (2008) (92)
- Premature Schwann Cell Differentiation and Hypermyelination in Mice Expressing a Targeted Antagonist of the POU Transcription Factor SCIP (1995) (91)
- Expression of theTyro4/Mek4/Cek4Gene Specifically Marks a Subset of Embryonic Motor Neurons and Their Muscle Targets (1996) (88)
- Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum (2005) (87)
- Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells (2015) (85)
- Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium. (2008) (77)
- Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. (2008) (77)
- Phosphatidylserine Is the Signal for TAM Receptors and Their Ligands. (2017) (73)
- A novel mechanism for the transcriptional regulation of Wnt signaling in development. (2011) (72)
- A critical role for the EphA3 receptor tyrosine kinase in heart development. (2007) (71)
- Structure and expression of the Tyro 10 receptor tyrosine kinase. (1994) (68)
- Neuronal and glial cell biology (2002) (67)
- MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis (2017) (66)
- VAX1 mutation associated with microphthalmia, corpus callosum agenesis, and orofacial clefting: The first description of a VAX1 phenotype in humans (2012) (64)
- Neuregulin-1 and Myelination (2006) (64)
- Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia (2017) (61)
- The gene encoding the transcription factor SCIP has features of an expressed retroposon. (1991) (57)
- Studies on cultured Schwann cells: the induction of myelin synthesis, and the control of their proliferation by a new growth factor. (1981) (57)
- Induction of the myelin proteolipid protein (PLP) gene in C6 glioblastoma cells: functional analysis of the PLP promotor (1991) (55)
- Blood clots and TAM receptor signalling in COVID-19 pathogenesis (2020) (53)
- Molecular biology of the major myelin genes (1986) (53)
- Selective disruption of neuregulin-1 function in vertebrate embryos using ribozyme-tRNA transgenes. (1998) (48)
- Multiple Regulatory Elements Control Transcription of the Peripheral Myelin Protein Zero Gene* (1997) (47)
- The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. (2009) (46)
- A Transgenic Mouse Model for Human Hereditary Neuropathy with Liability to Pressure Palsies (1997) (44)
- Hedgehog-regulated localization of Vax2 controls eye development. (2006) (43)
- Stromal-cell regulation of natural killer cell differentiation (2007) (43)
- Eph receptors and ephrin ligands in axon guidance. (2007) (40)
- A Coherent Nomenclature for Eph Receptors and Their Ligands (1997) (36)
- Genetic Dissection of EphA Receptor Signaling Dynamics during Retinotopic Mapping (2011) (34)
- Transcriptome Analysis of Neural Progenitor Cells by a Genetic Dual Reporter Strategy (2011) (34)
- Cell-specific action and mutable structure of a transcription factor effector domain. (1993) (33)
- Evectins: vesicular proteins that carry a pleckstrin homology domain and localize to post-Golgi membranes. (1999) (33)
- SREBP-1c expression in Schwann cells is affected by diabetes and nutritional status (2007) (32)
- Rules for Ribozymes (1998) (31)
- Hypomyelinating peripheral neuropathies and schwannomas in transgenic mice expressing SV40 T-antigen (1994) (29)
- TAM receptors in cardiovascular disease (2019) (29)
- Disturbed distribution of proliferative brain cells during lupus-like disease (2009) (28)
- Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motility (2000) (26)
- Dominant-negative isoforms of Tcf/Lef proteins in development and disease (2011) (25)
- EphA3 Null Mutants Do Not Demonstrate Motor Axon Guidance Defects (2003) (25)
- Use of a biotinylated probe and in situ hybridization for light and electron microscopic localization of P0 mRNA in myelin-forming Schwann cells (2004) (22)
- Defining Microglial States and Nomenclature: A Roadmap to 2030 (2022) (20)
- Glial growth factor: a mitogenic polypeptide of the brain and pituitary. (1983) (20)
- The human TYRO3 gene and pseudogene are located in chromosome 15q14-q25. (1993) (19)
- Heterogeneous Nuclear Ribonucleoprotein P2 Is an Autoantibody Target in Mice Deficient for Mer, Axl, and Tyro3 Receptor Tyrosine Kinases1 (2006) (19)
- Is the TAM Receptor Axl a Receptor for Lymphocytic Choriomeningitis Virus? (2013) (17)
- Complement factors in adult peripheral nerve: a potential role in energy metabolism (2004) (16)
- Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer (2020) (16)
- A molecular mechanism for the topographic alignment of convergent neural maps (2017) (15)
- Refined localization of dominant intermediate Charcot-Marie-Tooth neuropathy and exclusion of seven known candidate genes in the region (2003) (15)
- The gene encoding peripheral myelin protein zero is located on mouse chromosome 1 (1990) (14)
- About This Journal (1995) (13)
- The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation. (1996) (13)
- Insertional mutation at the ld locus (again!) in a line of transgenic mice. (1990) (13)
- Expression and Activity of the Transcription Factor SCIP during Glial Differentiation and Myelination (1991) (12)
- Recitative and aria (1993) (11)
- Isolation and analysis of the gene encoding peripheral myelin protein zero. (2008) (10)
- Molecular biology of myelination (1995) (10)
- Adopting ALK and LTK (2015) (10)
- Transcriptional regulation of the development of neurons and glia (1993) (10)
- B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP. (1994) (8)
- Heterogeneous Nuclear Ribonucleoprotein P2 Is an Autoantibody Target in Mice Deficient for Mer, Axl, and Tyro3 Receptor Tyrosine Kinases (2005) (8)
- Unwrapping myelination (1996) (6)
- Single cell analysis of the expression of a nuclear protein, SCIP, by fluorescent immunohistochemistry visualized with confocal microscopy (1993) (6)
- The dense-core plaques of Alzheimer’s disease are granulomas (2022) (6)
- A ligand for ALK (2015) (5)
- Natural killer cell differentiation driven by Tyro 3 receptor tyrosine kinases (2006) (4)
- Microglia actively remodels adult hippocampal neurogenesis through the phagocytosis secretome (2019) (4)
- Transcriptional Controls Underlying Schwann Cell Differentiation and Myelination (1990) (3)
- Molecular Biology of the Genes Encoding the Major Myelin Proteins (1987) (3)
- Editorial Evolution (2002) (2)
- Eph receptors and ligands in axon pathway choice, target recognition, and synaptogenesis. (1998) (2)
- 03.05 The tam receptors axl and mer play a protective role in a temporal and spatial manner in inflammatory arthritis (2017) (2)
- Targeted Disruption of GAS6-Mertk Pathway Leads to Defects in Physiological Clearance of Expelled Nuclei from Erythroblasts by Bone Marrow Macrophages. (2007) (2)
- Mitogen signal (1990) (2)
- In vitro studies on axon-Schwann cell interaction (1985) (2)
- The TAM receptor tyrosine kinases Axl and Mer drive the maintenance of highly phagocytic macrophages (2022) (2)
- The Myelination Cascade (1990) (1)
- Author response: Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities (2014) (1)
- The TAM receptors Axl and Mer play a joint-specific protective role in experimental arthritis (2016) (1)
- Early death in a mouse model of Alzheimer’s disease exacerbated by microglial loss of TAM receptor signaling (2022) (1)
- The gene encoding the transcription factor SCIP has features of an expressed retroposon (1991) (0)
- Crucial roles of Sp1 in the transcriptional regulation of LIGHT gene by Axl in T cell lymphoma (88.13) (2009) (0)
- Growth Arrest-Specific Gene 6 product modulates innate immunity in sepsis (2008) (0)
- The TAM Receptor Family (2015) (0)
- Axons regulate receptor genes Schwann cell expression of the major myelin and NGF (2005) (0)
- A microglia-CD4+ T cell partnership generates protective anti-tumor immunity to glioblastoma (2022) (0)
- Lymphocytic Choriomeningitis Virus? Is the TAM Receptor Axl a Receptor for (2014) (0)
- Differential TAM receptor regulation of hepatic physiology and injury (2020) (0)
- A NEW MYELINATION GENE (1997) (0)
- SCHWANN-CEIL-SPECIFIC GENE EXPRESSION IN TRANSGENIC MICE: 138 (1989) (0)
- Tyro3 Promotes the Maturation of Glutamatergic Synapses (2022) (0)
- Developmental neurobiology. Recitative and aria. (1993) (0)
- Protein S Is A Mer Ligand For Rpe-mediated Phagocytosis Of Photoreceptors In-vivo (2011) (0)
- Axon Growth and Guidance (2007) (0)
- EPHA receptors and topographic wiring of the eye to the brain (2006) (0)
- Table of Contents (1996) (0)
- A1.05 The mer tyrosine kinase receptor plays a protective role in joint inflammation by mediating efferocytosis (2016) (0)
- Neuronal and glial cell biology (1998) (0)
- A Correction to the Perspective Titled "Neuregulin-1 and Myelination" by G. Lemke. (2006) (0)
- 03.06 Mer-mediated efferocytosis tempers arthritis by preventing neutrophil littering in the joint (2017) (0)
- Gas6 and Its Receptors Are Implicated in Sepsis as Modulators of Innate Immunity. (2007) (0)
- REVIEW Neuregulins in Development (1996) (0)
- C0490: Role of Platelet Protein S in Primary Hemostasis in Mice (2014) (0)
- Author response: A molecular mechanism for the topographic alignment of convergent neural maps (2016) (0)
- Soluble Axl Is Generated by ADAM10-Dependent Cleavage and Associates with Gas6 in Mouse Serum (2011) (0)
- Neuronal and glial cell biology (1995) (0)
- How macrophages deal with death (2019) (0)
- Table of Contents (1991) (0)
- Stephen F. Heinemann: A true original (2014) (0)
- for Mer, Axl, and Tyro3 Receptor Tyrosine Is an Autoantibody Target in Mice Deficient Heterogeneous Nuclear Ribonucleoprotein P2 (2013) (0)
- Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models (2022) (0)
- Blood clots and TAM receptor signalling in COVID-19 pathogenesis (2020) (0)
- Precocious depletion of retinal progenitor population from the impaired notch signaling in pten-deficient retina (2009) (0)
- A Conversation with (2013) (0)
- Clearance of Apoptotic Cells Different Axl/Mertk/Tyro3 Receptors in Macrophages and Dendritic Cells Use (2007) (0)
- T cell derived Protein S inhibits the activation of Dendritic cells through the TAM receptors Axl and Mer: O-26. (2011) (0)
- The Axl/Gas6 phagocytosis receptor system is constitutively upregulated by Langerhans cells in response to epidermal TGF-β1. (147.15) (2011) (0)
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What Schools Are Affiliated With Greg Lemke?
Greg Lemke is affiliated with the following schools:
