Gregory P. Downey
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Computer Science
Gregory P. Downey's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Gregory P. Downey's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. (2011) (1194)
- Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. (2007) (635)
- Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries. (1989) (629)
- Efficacy and safety of sirolimus in lymphangioleiomyomatosis. (2011) (523)
- Neutrophil activation and acute lung injury (2001) (426)
- Leukocyte elastase: physiological functions and role in acute lung injury. (2001) (341)
- Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions1 (2003) (331)
- The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans. (2004) (330)
- Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury. (2009) (325)
- Oxidative stress and acute lung injury. (2003) (273)
- The Role of Actin-binding Protein 280 in Integrin-dependent Mechanoprotection* (1998) (262)
- The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance (2013) (242)
- Cystic fibrosis mouse models. (2007) (235)
- Activation of the mitogen-activated protein kinase signaling pathway in neutrophils. Role of oxidants. (1994) (226)
- An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. (1994) (225)
- Neutrophil granule contents in the pathogenesis of lung injury (2006) (223)
- Rapidly progressive bronchiolitis obliterans with organizing pneumonia. (1994) (219)
- Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass. (2004) (215)
- Focal localization of the NHE‐1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH. (1993) (202)
- Potentiation of the oxidative burst of human neutrophils. A signaling role for L-selectin. (1994) (201)
- Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management. (2016) (196)
- Retention of leukocytes in capillaries: role of cell size and deformability. (1990) (195)
- Proteases and lung injury (2003) (190)
- Neutrophil-mediated epithelial injury during transmigration: role of elastase. (2001) (184)
- Importance of MEK in neutrophil microbicidal responsiveness. (1998) (184)
- Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C (1992) (181)
- Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. (2011) (172)
- Sodium arsenite induces heat shock protein‐72 kilodalton expression in the lungs and protects rats against sepsis (1994) (172)
- Neutrophil sequestration and migration in localized pulmonary inflammation. Capillary localization and migration across the interalveolar septum. (1993) (168)
- Neutrophil transmigration triggers repair of the lung epithelium via β-catenin signaling (2011) (166)
- Signaling Functions of L-selectin (1995) (165)
- Serum VEGF-D a concentration as a biomarker of lymphangioleiomyomatosis severity and treatment response: a prospective analysis of the Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus (MILES) trial. (2013) (149)
- Mechanisms of leukocyte motility and chemotaxis. (1994) (149)
- MurineHepatitis Virus Strain 1 Produces a Clinically Relevant Model of Severe Acute Respiratory Syndrome in A/J Mice (2006) (145)
- Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils. (1988) (143)
- Targeted Deletion of fgl2 Leads to Impaired Regulatory T Cell Activity and Development of Autoimmune Glomerulonephritis1 (2008) (141)
- Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages. (2014) (141)
- CD44 is a phagocytic receptor. (2006) (141)
- Regulation of tyrosine phosphorylation in neutrophils by the NADPH oxidase. Role of reactive oxygen intermediates. (1993) (137)
- Remote ischemic preconditioning decreases adhesion and selectively modifies functional responses of human neutrophils. (2010) (134)
- Anti-synthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia. (2009) (134)
- Intracellular pH regulation during spreading of human neutrophils (1996) (133)
- Regulation of neutrophil activation in acute lung injury. (1999) (132)
- Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells. (2005) (131)
- Lung inflammation as a therapeutic target in cystic fibrosis. (2004) (131)
- Mechanisms of lipopolysaccharide-induced neutrophil retention. Relative contributions of adhesive and cellular mechanical properties. (1992) (130)
- Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease. (2016) (129)
- Neutrophil apoptosis: a marker of disease severity in sepsis and sepsis-induced acute respiratory distress syndrome (2006) (128)
- Age and sex dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis. (2011) (125)
- Lymphangioleiomyomatosis Diagnosis and Management: High‐Resolution Chest Computed Tomography, Transbronchial Lung Biopsy, and Pleural Disease Management. An Official American Thoracic Society/Japanese Respiratory Society Clinical Practice Guideline (2017) (124)
- Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway. (2006) (121)
- L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration. (2003) (119)
- Effects of the stress response in septic rats and LPS-stimulated alveolar macrophages: evidence for TNF-alpha posttranslational regulation. (1996) (117)
- Actin assembly in electropermeabilized neutrophils: role of intracellular calcium (1990) (116)
- Phagosomal Maturation, Acidification, and Inhibition of Bacterial Growth in Nonphagocytic Cells Transfected with FcγRIIA Receptors* (1999) (116)
- ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization. (1994) (115)
- A Novel Model System for Characterization of Phagosomal Maturation, Acidification, and Intracellular Collagen Degradation in Fibroblasts* (2000) (109)
- Intracellular signaling in neutrophil priming and activation. (1995) (109)
- Control of vesicle fusion by a tyrosine phosphatase (2004) (107)
- Role of innate immune cells and their products in lung immunopathology. (2008) (106)
- Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials (2013) (104)
- Matrix Metalloproteinase Induction of Rac1b, a Key Effector of Lung Cancer Progression (2012) (103)
- Signaling functions of L-selectin in neutrophils: alterations in the cytoskeleton and colocalization with CD18. (1999) (103)
- Increased Po2 alters the bioelectric properties of fetal distal lung epithelium. (1996) (98)
- Signalling platforms that modulate the inflammatory response: new targets for drug development (2006) (96)
- Cytosolic Phospholipase A2-α Is Necessary for Platelet-activating Factor Biosynthesis, Efficient Neutrophil-mediated Bacterial Killing, and the Innate Immune Response to Pulmonary Infection (2005) (96)
- Translocation of the tetraspanin CD63 in association with human eosinophil mediator release. (2002) (96)
- Neutrophil retention in model capillaries: deformability, geometry, and hydrodynamic forces. (1988) (95)
- Role of the actin cytoskeleton in insulin action (1999) (93)
- Immune function in patients with Shwachman–Diamond syndrome (2001) (93)
- On, around, and through: neutrophil-endothelial interactions in innate immunity. (2011) (91)
- Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences. (2009) (86)
- Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP (1991) (85)
- The basis of a more contagious 501Y.V1 variant of SARS-CoV-2 (2021) (85)
- Molecular pathogenesis of lymphangioleiomyomatosis: lessons learned from orphans. (2007) (85)
- Deficiency of Src Homology 2-Containing Phosphatase 1 Results in Abnormalities in Murine Neutrophil Function: Studies in Motheaten Mice1 (2000) (84)
- LSP1 modulates leukocyte populations in resting and inflamed peritoneum. (2000) (81)
- The immunoglobulin light chain related protein lambda 5 is expressed on the surface of mouse pre-B cell lines and can function as a signal transducing molecule. (1991) (80)
- Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression* (1998) (75)
- Regulation of Src Homology 2-containing Tyrosine Phosphatase 1 during Activation of Human Neutrophils (1997) (75)
- Inhibition of neutrophil oxidative burst and granule secretion by Wortmannin: Potential role of MAP kinase and renaturable kinases (1997) (73)
- Involvement of Cytosolic Phospholipase A2 and Secretory Phospholipase A2 in Arachidonic Acid Release from Human Neutrophils1 (2000) (73)
- Enhanced Susceptibility to Pulmonary Infection withBurkholderia cepacia inCftr−/− Mice (2001) (71)
- Negative regulation of myeloid cell proliferation and function by the SH2 domain-containing tyrosine phosphatase-1. (1999) (70)
- Regenerative Medicine and the Developing World (2006) (70)
- Chemotactic Peptide-induced Activation of MEK-2, the Predominant Isoform in Human Neutrophils (1996) (70)
- Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway. (2009) (69)
- Volume regulation in leukocytes: Requirement for an intact cytoskeleton (1995) (69)
- 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro (2021) (69)
- Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases (1996) (67)
- Leukocyte elastase induces epithelial apoptosis: role of mitochondial permeability changes and Akt. (2004) (67)
- Leukocyte and platelet margination within microvasculature of rabbit lungs. (1990) (66)
- CD44-mediated phagocytosis induces inside-out activation of complement receptor-3 in murine macrophages. (2007) (65)
- Involvement of actin filaments and integrins in the binding step in collagen phagocytosis by human fibroblasts. (2001) (64)
- Chemotactic peptides induce phosphorylation and activation of MEK-1 in human neutrophils. (1994) (60)
- Matrix metalloproteinases and protein tyrosine kinases: potential novel targets in acute lung injury and ARDS. (2014) (59)
- Conventional mechanical ventilation is associated with bronchoalveolar lavage-induced activation of polymorphonuclear leukocytes: a possible mechanism to explain the systemic consequences of ventilator-induced lung injury in patients with ARDS. (2002) (59)
- Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury (2012) (58)
- Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury. (2013) (58)
- Tyrosine phosphatase MEG2 modulates murine development and platelet and lymphocyte activation through secretory vesicle function (2005) (55)
- Role of PAR2 in murine pulmonary pseudomonal infection. (2008) (54)
- Enhancement of pulmonary inflammation by PGE2: evidence for a vasodilator effect. (1988) (53)
- Successful treatment of juvenile laryngeal papillomatosis-related multicystic lung disease with cidofovir: case report and review of the literature. (2000) (53)
- Inhibition of CD45 during neutrophil activation. (1997) (53)
- Microfilament assembly is required for antigen-receptor-mediated activation of human B lymphocytes. (1991) (52)
- Targeting transgene expression for cystic fibrosis gene therapy. (2001) (52)
- Human neutrophil peptides and phagocytic deficiency in bronchiectatic lungs. (2009) (49)
- Subglottic stenosis complicating Wegener's granulomatosis: surgical repair as a viable treatment option. (1996) (49)
- The basis of a more contagious 501Y.V1 variant of SARS-CoV-2 (2021) (48)
- Inactivation of Macrophage Rab7 by Burkholderia cenocepacia (2010) (47)
- Human epidermal growth factor receptor signaling in acute lung injury. (2012) (46)
- Neutrophil Intercellular Communication in Acute Lung Injury: Emerging Roles of Microparticles and Gap Junctions. (2013) (46)
- Conventional Mechanical Ventilation Is Associated with Bronchoalveolar Lavage-induced Activation of Polymorphonuclear Leukocytes: A Possible Mechanism to Explain the Systemic Consequences of Ventilator-induced Lung Injury in Patients with ARDS (2002) (45)
- Rare lung diseases III: pulmonary Langerhans' cell histiocytosis. (2010) (44)
- The Protein Tyrosine Phosphatase SHP-2 Regulates Interleukin-1-induced ERK Activation in Fibroblasts* (2003) (42)
- Air travel in women with lymphangioleiomyomatosis (2006) (42)
- Lipolysaccharide-induced monocyte retention in the lung. Role of monocyte stiffness, actin assembly, and CD18-dependent adherence. (1994) (41)
- Measurements of Phagocytosis and Phagosomal Maturation (2004) (41)
- Neuroleptic malignant syndrome. Patient with unique clinical and physiologic features. (1984) (40)
- Factors affecting attainment of paid employment after lung transplantation. (2004) (40)
- SHP-2 Modulates Interleukin-1-induced Ca2+ Flux and ERK Activation via Phosphorylation of Phospholipase Cγ1* (2005) (40)
- Protein-tyrosine Phosphatase MEG2 Is Expressed by Human Neutrophils (2002) (40)
- Adhesion Molecules: Master Controllers of the Circulatory System. (2016) (40)
- Perspective Oxidative Stress and Acute Lung Injury (2003) (40)
- Abnormalities in the pulmonary innate immune system in cystic fibrosis. (2006) (39)
- Signaling mechanisms in human neutrophils (1995) (39)
- Divergent functions of Toll-like receptors during bacterial lung infections. (2014) (39)
- Respiratory Health after Military Service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop Report (2019) (38)
- Neutrophils increase volume during migration in vivo and in vitro. (1994) (37)
- Phosphorylation of SHP-2 Regulates Interactions between the Endoplasmic Reticulum and Focal Adhesions to Restrict Interleukin-1-induced Ca2+ Signaling* (2006) (37)
- Lipolysaccharide-Induced Monocyte Retention in the Lung (1994) (37)
- Investigating the role of nucleotide-binding oligomerization domain-like receptors in bacterial lung infection. (2014) (37)
- "Effect of mechanical deformation on structure and function of polymorphonuclear leukocytes". (1997) (36)
- Airway inflammation and infection in congenital bilateral absence of the vas deferens. (2004) (34)
- Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42 (2012) (34)
- Emerging Roles of Inflammasomes in Acute Pneumonia (2018) (34)
- Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells. (2001) (34)
- Initial interaction of leukocytes within the microvasculature: deformability, adhesion, and transmigration. (1995) (32)
- Accommodation after lung xenografting from hamster to rat1 (2003) (32)
- Okadaic acid‐induced actin assembly in neutrophils: Role of protein phosphatases (1993) (30)
- Role of cytoskeleton in volume regulation of rabbit proximal tubule in dilute medium. (1992) (30)
- Mechanisms of acute lung injury (1997) (29)
- Tyrosine phosphatase SHP‐2 regulates IL‐1 signaling in fibroblasts through focal adhesions (2006) (28)
- Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness. (2014) (28)
- IL‐1 induced release of Ca2+ from internal stores is dependent on cell‐matrix interactions and regulates ERK activation (2003) (28)
- IL‐1β enhances cell adhesion to degraded fibronectin (2012) (28)
- 501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro (2021) (28)
- Tyrosine phosphorylation is essential for microfilament assembly in B lymphocytes. (1991) (28)
- Actin assembly in electropermeabilized neutrophils: role of G-proteins. (1989) (27)
- Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways. (1990) (27)
- Coagulation inhibitors in sepsis and disseminated intravascular coagulation (2000) (27)
- Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis (2019) (26)
- Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells (2021) (26)
- Mechanical ventilation: physiological and clinical applications (2003) (25)
- Tyrosine phosphatase PTPalpha regulates focal adhesion remodeling through Rac1 activation. (2008) (25)
- The Lambda variant of SARS-CoV-2 has a better chance than the Delta variant to escape vaccines (2021) (25)
- Isolated Cystic Lung Disease: An Algorithmic Approach to Distinguishing Birt-Hogg-Dubé Syndrome, Lymphangioleiomyomatosis, and Lymphocytic Interstitial Pneumonia. (2019) (24)
- Rare lung diseases. II Pulmonary alveolar proteinosis (2008) (24)
- Activation of permeabilized neutrophils: role of anions. (1992) (23)
- Update on the Features and Measurements of Experimental Acute Lung Injury in Animals: An Official American Thoracic Society Workshop Report (2022) (23)
- Activation of Na+-permeant Cation Channel by Stretch and Cyclic AMP-dependent Phosphorylation in Renal Epithelial A6 Cells (1997) (22)
- Up-regulation of functional CXCR4 expression on human lymphocytes in sepsis (2006) (22)
- Puromycin aminonucleoside inhibits mesangial cell-induced contraction of collagen gels by stimulating production of reactive oxygen species. (1995) (22)
- Involvement of the actin network in insulin signalling. (1997) (22)
- Cytosolic Phospholipase A2-α Is Necessary for Platelet-activating Factor Biosynthesis, Efficient Neutrophil-mediated Bacterial Killing, and the Innate Immune Response to Pulmonary Infection: cPLA2-α DOES NOT REGULATE NEUTROPHIL NADPH OXIDASE ACTIVITY* (2008) (21)
- Protein-tyrosine Phosphatase-α and Src Functionally Link Focal Adhesions to the Endoplasmic Reticulum to Mediate Interleukin-1-induced Ca2+ Signaling* (2009) (21)
- Underlying chronic granulomatous disease in a patient with bronchocentric granulomatosis (2003) (19)
- Importance of Protein-tyrosine Phosphatase-α Catalytic Domains for Interactions with SHP-2 and Interleukin-1-induced Matrix Metalloproteinase-3 Expression* (2010) (19)
- The importance of matrix metalloproteinase-3 in respiratory disorders (2014) (19)
- Resolving the scar of pulmonary fibrosis. (2011) (18)
- Neutrophil intercellular communication in acute lung injury. Emerging roles of microparticles and gap junctions. (2013) (18)
- Stimulation of glucose transport in L6 muscle cells by long‐term intermittent stretch—relaxation (1992) (18)
- Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression. (2013) (18)
- Rare lung disease II: pulmonary alveolar proteinosis. (2008) (18)
- Importance of MEK in Neutrophil Microbicidal Responsiveness 1 (1997) (17)
- Hemodilution reduces early reperfusion injury in an ex vivo rabbit lung preservation model. (1994) (16)
- Cyclic nucleotides modulate genioglossus and hypoglossal responses to excitatory inputs in rats. (2006) (16)
- Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition (2019) (15)
- Role of caveolin-1 in regulation of inflammation: different strokes for different folks. (2008) (15)
- Localised pulmonary resection for bronchiectasis in hypogammaglobulinaemic patients. (1994) (15)
- Of fi cial American Thoracic Society / Japanese Respiratory Society Clinical Practice Guidelines : Lymphangioleiomyomatosis Diagnosis and Management (2016) (15)
- A unique renal lesion in common variable immunodeficiency. (2002) (15)
- Mitochondrial function is a critical determinant of IL‐1‐induced ERK activation (2005) (15)
- A novel method for long term bone marrow culture and genetic modification of murine neutrophils via retroviral transduction. (2009) (15)
- Neutrophil cell signaling in infection: role of phosphatidylinositide 3-kinase. (2003) (14)
- Monocyte‐Induced Endothelial Calcium Signaling Mediates Early Xenogeneic Endothelial Activation (2005) (14)
- Interactions of the Protein-tyrosine Phosphatase-α with the Focal Adhesion Targeting Domain of Focal Adhesion Kinase Are Involved in Interleukin-1 Signaling in Fibroblasts* (2014) (14)
- Receptor-mediated actin assembly in electropermeabilized neutrophils: role of intracellular pH. (1989) (14)
- Death of the septic monocyte: is more better? (2006) (13)
- ROS stimulate reorganization of mesangial cell-collagen gels by tyrosine kinase signaling. (1999) (12)
- Biological markers in diagnosing, monitoring, and treating asthma: a focus on noninvasive measurements. (2004) (12)
- Control of local blood flow in pulmonary inflammation: role for neutrophils, PAF, and thromboxane. (1991) (12)
- A ternary complex comprising FAK, PTPα and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts. (2016) (11)
- The yin and yang of cystic fibrosis transmembrane conductance regulator function: implications for chronic lung disease. (2013) (11)
- The Importance of Tyrosine Phosphorylation Control of Cellular Signaling Pathways in Respiratory Disease: pY and pY Not (2018) (10)
- Role of cytoskeleton in isotonic cell volume control of rabbit proximal tubules. (1991) (10)
- Update in Cystic Fibrosis 2018. (2019) (10)
- Mechanisms of Neutrophil Mediated Injury (1996) (10)
- Progressive dyspnea associated with a crazy-paving appearance on a chest computed tomography scan. (2006) (10)
- Regulation of IL‐1 signaling through control of focal adhesion assembly (2018) (10)
- Rare lung diseases I--Lymphangioleiomyomatosis. (2006) (9)
- Heterozygous Meg2 Ablation Causes Intraocular Pressure Elevation and Progressive Glaucomatous Neurodegeneration (2018) (8)
- Activation of mechanical responses in leukocytes. (1990) (8)
- A simplified model for en bloc double lung xenotransplantation from hamster to rat. (2002) (8)
- The Leucine-Rich Repeat Region of CARMIL1 Regulates IL-1-Mediated ERK Activation, MMP Expression, and Collagen Degradation. (2020) (8)
- Afghanistan Particulate Matter Enhances Pro-Inflammatory Responses in IL-13-Exposed Human Airway Epithelium via TLR2 Signaling (2018) (8)
- Role of PTPα in the Destruction of Periodontal Connective Tissues (2013) (8)
- Cytosolic Phospholipase A 2 - (cid:1) Is Necessary for Platelet-activating Factor Biosynthesis, Efficient Neutrophil-mediated Bacterial Killing, and the Innate Immune Response to Pulmonary Infection - (cid:1) DOES NOT REGULATE NEUTROPHIL NADPH OXIDASE ACTIVITY* (cPLA (2005) (7)
- Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis. (2022) (7)
- Patients' perceptions versus medical testing of function in women with lymphangioleiomyomatosis (LAM). (2005) (7)
- Protein-tyrosine phosphatase-α and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling. (2009) (6)
- Age-dependent neutrophil and blood flow responsiveness in acute pulmonary inflammation in rabbits. (1997) (6)
- Cytosolic Phospholipase A 2-Is Necessary for Platelet-activating Factor Biosynthesis , Efficient Neutrophil-mediated Bacterial Killing , and the Innate Immune Response to Pulmonary Infection cPLA (2004) (6)
- Reactive Oxygen Intermediates as Signaling Molecules Regulating Leukocyte Activation (1997) (6)
- PROTEASE-ACTIVATED RECEPTOR (PAR)1 ALTERS BIOELECTRIC PROPERTIES OF DISTAL LUNG EPITHELIA WITHOUT COMPROMISING BARRIER FUNCTION (2009) (6)
- Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10 (2022) (6)
- Focal adhesions and Ras are functionally and spatially integrated to mediate IL‐1 activation of ERK (2011) (6)
- Neutrophil products and alterations in epithelial junctional proteins: prevention of artifactual degradation. (2000) (6)
- Protein Tyrosine Phosphatase-α Amplifies TGF-β-Dependent Pro-Fibrotic Signaling in Lung Fibroblasts. (2020) (6)
- Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. (2020) (5)
- ICU Cornerstone: Changing our view of blood transfusions (2002) (5)
- It's much more than just pretty pictures. (2010) (5)
- Difficult asthma: consider all of the possibilities. (2000) (5)
- Cystic fibrosis: potential options for gene-directed therapies (2004) (4)
- Chapter 1 – Inflammation (2006) (4)
- NADPH oxidase-derived reactive oxygen intermediates regulate tyrosine phosphorylation in human neutrophils. (1994) (4)
- Transfection of lung cells in vitro and in vivo: effect of antioxidants and intraliposomal bFGF. (2003) (4)
- Human neutrophil peptides induce interleukin-8 production via P 2 Y 6 signaling pathway (2005) (3)
- IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice. (2020) (3)
- Current techniques in cell and molecular biology. (1995) (3)
- Calcified endobronchial mass in a 28-year-old man. (1990) (3)
- Role of Particulate Matter from Afghanistan and Iraq in Deployment-Related Lung Disease. (2021) (3)
- Early cellular events in the induction of murine hepatitis virus (MHV-3) induced macrophage procoagulant activity (PCA). (1993) (2)
- 15 – Injury and Repair (2016) (2)
- Injury and Repair of the Lung (2010) (2)
- Use of fluorescent probes to detect lipid signaling intermediates in macrophages. (2009) (2)
- Restarting Respiratory Clinical Research in the Era of the Coronavirus Disease 2019 Pandemic (2020) (2)
- How I Do It: Restarting Respiratory Clinical Research in the Era of the COVID19 Pandemic (2020) (2)
- Effect of alterations in early signal transduction events on the induction of procoagulant activity by murine hepatitis virus strain 3 in vitro. (1995) (2)
- ROS stimulate reorganization of mesangial cell-collagen gels by tyrosine kinase signaling. (1999) (2)
- Imaging of multisystem Langerhans cell histiocytosis in an adult (2007) (2)
- Single Cell RNA Sequencing Reveals a Unique Monocyte Population in Bronchoalveolar Lavage Cells of Mice Challenged with Afghanistan Particulate Matter and Allergen. (2021) (2)
- and deformability Retention of leukocytes in capillaries: role of cell size (2012) (1)
- Protein tyrosine phosphatase-alpha (PTPα) promotes profibrotic responses in lung fibroblasts (2017) (1)
- Saracatinib Is a Potential Novel Therapeutic for Pulmonary Fibrosis (2020) (1)
- BACTERIAL INFECTIONS OF THE LUNG (2008) (1)
- Colocalization with CD 18 Neutrophils : Alterations in the Cytoskeleton Signaling Functions of L-Selectin in (1999) (1)
- Proteinase-Activated Receptor-1 Mediates Elastase-Induced Apoptosis of Human Lung (2005) (1)
- Chasing the Lymph: New Clues for the Management of Idiopathic Plastic Bronchitis. (2016) (1)
- Reply: defining lung injury in animals. (2013) (1)
- Mechanisms of Fibrosis (2019) (1)
- Neutrophil Migration across Cultured Lung Epithelium Induces Modulation of the WNT-β-Catenin Pathway. (2009) (1)
- Baseline Serum VEGF-D Levels Are Associated With Disease Severity And Treatment Response In Lymphangioleiomyomatosis (2011) (1)
- Role of ponticulin in pseudopod dynamics, cell-cell adhesion, and mechanical stability of an amoeboid membrane skeleton. (1998) (0)
- Chemotaxis Compass Rac1 is the small GTPase Responsible for Regulating the Neutrophil (2013) (0)
- Chapter 11 – Host Defenses (2008) (0)
- ResponsivenessImportance of MEK in Neutrophil Microbicidal (1997) (0)
- Identification and Characterization of Protein Tyrosine Phosphatases Expressed in Human Neutrophils (2001) (0)
- Beta-Catenin Mitigates Epithelial Injury Induced By Neutrophil Transmigration (2011) (0)
- Protein tyrosine phosphatase Meg2 deficient mice - A powerful model to study glaucoma disease? (2013) (0)
- Non-immunologic mechanisms of pulmonary defense (2006) (0)
- bleomycin-induced lung injury A micro-CT analysis of murine lung recruitment in (2015) (0)
- Protein Tyrosine Phosphatase-± Deficiency In Mice Protects Against Bleomycin-Induced Lung Fibrosis And Causes Aberrant Response To TGF² (2011) (0)
- The Receptor Binding Domain of SARS-CoV-2 Lambda Variant Has a Better Chance Than the Delta Variant in Evading BNT162b2 COVID-19 mRNA Vaccine-Induced Humoral Immunity (2022) (0)
- Yes-Associated Protein (YAP) Is Critical in Epithelial Repair After Acute Lung Injury (2021) (0)
- Reply to coates and bush (2004) (0)
- Lymphangioleiomyomatosis and Other Cystic Lung Diseases. (2023) (0)
- Heterozygous Meg2 Ablation Causes Intraocular Pressure Elevation and Progressive Glaucomatous Neurodegeneration (2018) (0)
- NeutrophilsArachidonic Acid Release from Human in 2 and Secretory Phospholipase A 2 Involvement of Cytosolic Phospholipase A (2000) (0)
- Assessment of the Role of Calcium in Neutrophil Activation Using Electropermeabilized Cells (1990) (0)
- Regenerative Medicine and the Developing (2006) (0)
- Mechanisms and Treatment of Deployment-Related Lung Injury: Repair of the Injured Epithelium (2017) (0)
- Phorbol Ester-Induced Actin Assembly in Neutrophils : Role ofProtein Kinase C (2002) (0)
- Desert Particulate Matter Exposure Induces Interleukin-1 Family Mediated Inflammation and Remodeling of the Mucociliary Airway Epithelium (2020) (0)
- Contents Vol. 2, 2010 (2010) (0)
- Regulation of Neutrophil Activation in Acute Lung Injury and SIRS (2002) (0)
- Considerations in Selecting Venues for the ATS International Conference: Balancing Competing Priorities of the Society's Diverse Membership. (2023) (0)
- Supplementary Material for: Inactivation of Macrophage Rab7 by Burkholderia cenocepacia (2017) (0)
- Obesity-Associated Elevation Of Low Density Lipoprotein Levels Affects Neutrophil Function (2012) (0)
- Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in In Vitro, In Vivo and Ex Vivo Models of Pulmonary Fibrosis (2022) (0)
- The Remote Ischemic Preconditioning Stimulus Modifies Inflammatory (2004) (0)
- Subject Index Vol. 2, 2010 (2010) (0)
- PTPα Is a Regulator of Fibroproliferation During ARDS (2021) (0)
- Late-breaking abstract: Protein tyrosine phosphatase (PTP)α promotes profibrotic responses in fibroblasts via Smad signaling (2014) (0)
- Selective Effects on Neutrophil Functions Rac1 Deletion in Mouse Neutrophils Has (2003) (0)
- closure during cyclic mechanical strain Mathematical modeling of airway epithelial wound (2015) (0)
- Lymphangioleiomyomatosis Air travel in women with (2007) (0)
- IL-1β Delays Fibroblast Apoptosis Via PI3K/Akt Dependent Pathway. (2009) (0)
- Tickle my innards (2006) (0)
- List of Contributors (2019) (0)
- Matrix Metalloproteinase 3 (MMP3) Null Mice Are Protected from Bleomycin (BLM) Induced Pulmonary Fibrosis by Suppression of Vascular Endothelial Growth Factor (VEGF). (2009) (0)
- Role of Leukocytes in Sepsis and Lung Injury (2002) (0)
- PTP-Meg2 - A New Functional Player During Early Retinogenesis? (2012) (0)
- Epithelial Injury in Sepsis and ARDS: Role of Leukocyte-Derived Proteases (2002) (0)
- 501 Activation of PAR-2 Induces Myofibroblast Transformation via a TGF-β and GSK-3β/β-catenin Dependent Pathway in Tissue Remodeling in the Asthmatic Lung (2012) (0)
- Of fi cial American Thoracic Society/Japanese Respiratory Society Clinical Practice Guidelines: Lymphangioleiomyomatosis Diagnosis and Management (2016) (0)
- Role of ALDH2 in Fibroproliferation After Acute Lung Injury (2023) (0)
- Neurodegeneration, reactive gliosis and complement activation in glaucomatous protein tyrosine phosphatase Meg2 deficient mice (2014) (0)
- Chapter 22 – Pulmonary Host Defenses (2012) (0)
- ²-catenin Signaling Accelerates Epithelial Repair After Neutrophil-mediated Injury In ALI (2010) (0)
- PAR-2 agonists induce TGF-β and EMT leading to lung fibrosis (2013) (0)
- Desert Particulate Matter From Afghanistan Increases Airway Obstruction in Human Distal Lungs Exposed to Type 2 Cytokine IL-13 (2023) (0)
- PTPα Promotes Fibroproliferative Responses After Acute Lung Injury. (2022) (0)
- A novel role for CD63 in granule protein mobilization and release from eosinophils during degranulation (2002) (0)
- Taking It Off: New Insights into the Role of Tyrosine Phosphorylation-dependent Pathways in the Pathogenesis of Pulmonary Fibrosis. (2017) (0)
- Reply: Experimental Acute Lung Injury in Animals: With Age Comes Knowledge (2022) (0)
- RhoA and NFκB Dependent Secretion of IL-8 Induced by Mechanical Stretch of Calu-3 Cells. (2009) (0)
- Cigarette Smoke Induces WNT/Beta-Catenin Signaling And Exacerbates Inflammatory Injury To The Lung Epithelium (2011) (0)
- Protein Tyrosine Phosphatase-± Mediates Pro-Fibrotic Signaling In Murine Lung Fibroblasts Through TGF-² Responsiveness (2012) (0)
- Murine Neutrophil Function: Studies in Phosphatase 1 Results in Abnormalities in Deficiency of Src Homology 2-Containing (2000) (0)
- Domain-Containing Tyrosine Phosphatase-1 Proliferation and Function by the SH 2 Negative Regulation of Myeloid Cell (1999) (0)
- Inflammatory Cells of the Lung: Neutrophils (2018) (0)
- E-Cigarette Vape Impairs Lung Endothelial Barrier Function and Autophagy via Jun N-Terminal Kinase (2023) (0)
- Introduction to the 57th annual Thomas L. Petty Aspen Lung Conference: Rebuilding the injured lung. (2015) (0)
- PTPα Controls TGF-β-Dependent Fibrotic Signaling in Fibroproliferative ARDS (2020) (0)
- Canadian respirologists' experience with lymphangioleiomyomatosis. (2002) (0)
- CCN Growth Factors Accelerate Repair Of The Lung Epithelium After Neutrophil Transmigration (2012) (0)
- Mechanisms of Military Deployment-Related Lung Diseases: Desert Dust Exposure Induces Epidermal Differentiation of Both Human Airway Epithelial Stem Cells and the Mucociliary Airway Epithelium (2019) (0)
- signaling pathway Human neutrophil peptides induce interleukin-8 production via P2Y6 (2013) (0)
- Role of neutrophils in acute lung injury and repair (2011) (0)
- Integrated Genomics Approaches Identify Transcriptional Mediators and Epigenetic Responses to Afghan Desert Particulate Matter in Small Airway Epithelial Cells (2022) (0)
- Effect of high bath potassium concentration on cell volume of isolated proximal straight tubules (1992) (0)
- eosinophil mediator release Translocation of the tetraspanin CD63 in association with human (2013) (0)
- Quality of life after lung transplantation for lymphangioleiomyomatosis (LAM) (2003) (0)
- Protein-tyrosine Phosphatase- and Src Functionally Link Focal Adhesions to the Endoplasmic Reticulum to Mediate (2009) (0)
- Be the Change: Advancing Lung Health and Closing the Global Healthcare Gap (2022) (0)
- Rapid Neurologic Deterioration in a 29-Year-Old Pregnant Woman from Panama (1987) (0)
- Lymphangioleiomyomatosis (2008) (0)
- Proteinases in the pathogenesis of lymphangioleiomyomatosis lung disease: nibbling or chewing up the lung? (2022) (0)
- Gene expression in cardiac and lung xenografts (2003) (0)
- structure and function of polymorphonuclear leukocytes'' Invited Editorial on ''Effect of mechanical deformation on (2013) (0)
- Table of Contents (1994) (0)
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