Guido Verhoeven
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Biology
Guido Verhoeven's Degrees
- PhD Biomedical Sciences University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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(Suggest an Edit or Addition)Guido Verhoeven's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. (2004) (728)
- Increased lipogenesis in cancer cells: new players, novel targets (2006) (564)
- De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation. (2010) (547)
- Induction of Cancer Cell Apoptosis by Flavonoids Is Associated with Their Ability to Inhibit Fatty Acid Synthase Activity* (2005) (420)
- Overexpression of fatty acid synthase is an early and common event in the development of prostate cancer (2002) (368)
- Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells. (2007) (288)
- RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells. (2003) (269)
- The Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription (1999) (259)
- Coordinate regulation of lipogenic gene expression by androgens: evidence for a cascade mechanism involving sterol regulatory element binding proteins. (1997) (247)
- Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains. (2003) (246)
- Selective activation of the fatty acid synthesis pathway in human prostate cancer (2000) (246)
- RNA Interference–Mediated Silencing of the Acetyl-CoA-Carboxylase-α Gene Induces Growth Inhibition and Apoptosis of Prostate Cancer Cells (2005) (240)
- The role of androgens in sertoli cell proliferation and functional maturation: studies in mice with total or Sertoli cell-selective ablation of the androgen receptor. (2005) (229)
- Selective DNA binding by the androgen receptor as a mechanism for hormone-specific gene regulation (2001) (225)
- Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP. (1997) (214)
- Epigallocatechin‐3‐gallate is a potent natural inhibitor of fatty acid synthase in intact cells and selectively induces apoptosis in prostate cancer cells (2003) (199)
- Conditional Inactivation of Androgen Receptor Gene in the Nervous System: Effects on Male Behavioral and Neuroendocrine Responses (2009) (192)
- Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway (2000) (187)
- Role of the phosphatidylinositol 3'-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells. (2002) (181)
- Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway. (2001) (164)
- Relative Impact of Androgen and Estrogen Receptor Activation in the Effects of Androgens on Trabecular and Cortical Bone in Growing Male Mice: A Study in the Androgen Receptor Knockout Mouse Model (2006) (162)
- Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells (2014) (159)
- Androgens, lipogenesis and prostate cancer (2004) (159)
- Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains. (1999) (158)
- The Androgen-specific Probasin Response Element 2 Interacts Differentially with Androgen and Glucocorticoid Receptors* (1996) (151)
- Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells (1990) (150)
- Interleukin-1 stimulates steroidogenesis in cultured rat Leydig cells (1988) (146)
- Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype. (2005) (140)
- The effect of a sertoli cell-selective knockout of the androgen receptor on testicular gene expression in prepubertal mice. (2006) (137)
- Androgens and spermatogenesis: lessons from transgenic mouse models (2010) (135)
- Selective Ablation of the Androgen Receptor in Mouse Sertoli Cells Affects Sertoli Cell Maturation, Barrier Formation and Cytoskeletal Development (2010) (135)
- Alterations in thyroid status modulate apolipoprotein, hepatic triglyceride lipase, and low density lipoprotein receptor in rats. (1990) (134)
- Androgens markedly stimulate the accumulation of neutral lipids in the human prostatic adenocarcinoma cell line LNCaP. (1996) (133)
- Differences in DNA Binding Characteristics of the Androgen and Glucocorticoid Receptors Can Determine Hormone-specific Responses* (2000) (131)
- A factor in spent media from Sertoli cell-enriched cultures that stimulates steroidogenesis in Leydig cells (1985) (131)
- Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor‐α (2009) (131)
- High‐level expression of fatty acid synthase in human prostate cancer tissues is linked to activation and nuclear localization of Akt/PKB (2005) (127)
- Follicle-stimulating hormone and androgens increase the concentration of the androgen receptor in Sertoli cells. (1988) (127)
- Role of androgens in fetal testis development and dysgenesis. (2007) (123)
- Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform. (1999) (122)
- Spermatogenesis and sertoli cell activity in mice lacking sertoli cell receptors for follicle-stimulating hormone and androgen. (2008) (121)
- Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors (2010) (120)
- Androgen activation of the sterol regulatory element-binding protein pathway: Current insights. (2006) (117)
- Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. (2016) (116)
- Functional characterization of an androgen response element in the first intron of the C3(1) gene of prostatic binding protein. (1989) (115)
- Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor. (2005) (114)
- Androgen signaling in myocytes contributes to the maintenance of muscle mass and fiber type regulation but not to muscle strength or fatigue. (2009) (113)
- Change of Specificity Mutations in Androgen-selective Enhancers (2000) (110)
- Stimulation effect of neurotransmitters on the aromatization of testosterone by Sertoli cell-enriched cultures (1979) (110)
- Control of LNCaP proliferation and differentiation: Actions and interactions of androgens, Iα,25‐dihydroxycholecalciferol, all‐trans retinoic acid, 9‐cis retinoic acid, and phenylacetate (1996) (109)
- Tissue- and cell-specific functions of the androgen receptor revealed through conditional knockout models in mice (2012) (106)
- Androgen receptor expression is regulated by the phosphoinositide 3-kinase/Akt pathway in normal and tumoral epithelial cells. (2002) (106)
- LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids (1997) (105)
- The differentiation‐related gene 1, Drg1, is markedly upregulated by androgens in LNCaP prostatic adenocarcinoma cells (1999) (99)
- The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice. (2007) (99)
- Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation* (2007) (95)
- Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model (2007) (94)
- Biochemical characterization of peritoneal fluid in women during the menstrual cycle. (1980) (93)
- RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells. (2005) (92)
- Acute treatment with corticosteroids decreases IGF-1 and IGF-2 expression in the rat diaphragm and gastrocnemius. (1999) (91)
- Influence of development, estrogens, and food intake on apolipoprotein A-I, A-II, and E mRNA in rat liver and intestine. (1989) (89)
- Androgen receptor-dependent and independent atheroprotection by testosterone in male mice. (2010) (88)
- Cytosol androgen binding in submandibular gland and kidney of the normal mouse and the mouse with testicular feminization. (1976) (86)
- Direct action through the sertoli cells is essential for androgen stimulation of spermatogenesis. (2010) (83)
- Stimulatory effects of epidermal growth factor on steroidogenesis in Leydig cells (1986) (83)
- Androgens stimulate coordinated lipogenic gene expression in normal target tissues in vivo (2003) (77)
- Targeted Inactivation of the Androgen Receptor Gene in Murine Proximal Epididymis Causes Epithelial Hypotrophy and Obstructive Azoospermia (2009) (76)
- Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and male fertility in mice. (2006) (75)
- Implications of a polyglutamine tract in the function of the human androgen receptor. (2003) (75)
- Testicular peritubular cells secrete a protein under androgen control that inhibits induction of aromatase activity in Sertoli cells. (1988) (73)
- Different forms of alpha 2u-globulin in male and female rat urine. (1983) (72)
- Ammonium sulfate precipitation as a tool for the study of androgen receptor proteins in rat prostate and mouse kidney (1975) (67)
- Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice (2010) (66)
- Identification of Diazepam-binding Inhibitor/Acyl-CoA-binding Protein as a Sterol Regulatory Element-binding Protein-responsive Gene* (1998) (65)
- Peritubular myoid cells from immature rat testes secrete activin-A and express activin receptor type II in vitro. (1994) (64)
- Early effects of Sertoli cell-selective androgen receptor ablation on testicular gene expression. (2009) (64)
- Peritubular cell-Sertoli cell interactions: factors involved in PmodS activity. (2000) (64)
- Identification of an Androgen Response Element in Intron 8 of the Sterol Regulatory Element-binding Protein Cleavage-activating Protein Gene Allowing Direct Regulation by the Androgen Receptor* (2004) (63)
- Molecular and Cellular Endocrinology of the Testis (1994) (62)
- Interaction of the 90-kDa heat shock protein with native and in vitro translated androgen receptor and receptor fragments (1992) (61)
- Apolipoprotein A-IV messenger ribonucleic acid abundance is regulated in a tissue-specific manner. (1990) (60)
- Cryptorchidism in mice with an androgen receptor ablation in gubernaculum testis. (2012) (59)
- Development, food intake, and ethinylestradiol influence hepatic triglyceride lipase and LDL-receptor mRNA levels in rats. (1990) (58)
- Endocrine effects of high-dose ketoconazole therapy in advanced prostatic cancer. (1985) (58)
- Variable effects of different corticosteroids on plasma lipids, apolipoproteins, and hepatic apolipoprotein mRNA levels in rats. (1991) (58)
- Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside (2006) (57)
- E2F activity is biphasically regulated by androgens in LNCaP cells. (2001) (55)
- Regulation of inhibin secretion by Sertoli cell-enriched cultures. (1983) (55)
- Tissue-specific expression and androgen regulation of different genes encoding rat prostatic 22-kilodalton glycoproteins homologous to human and rat cystatin. (1990) (54)
- Effects of neurotransmitters and follicle stimulating hormone on the aromatization of androgens and the production of adenosine 3',5'-monophosphate by cultured testicular cells. (1980) (53)
- Interaction of androgen response elements with the DNA-binding domain of the rat androgen receptor expressed in Escherichia coli. (1991) (52)
- The syndromes of primary hormone resistance. (1979) (52)
- Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the human prostatic adenocarcinoma cell line LNCaP (1994) (52)
- Developmental changes in immunoreactive inhibin and FSH in plasma of chickens from hatch to sexual maturity. (1995) (52)
- Androgen receptor in cultured interstitial cells derived from immature rat testis. (1980) (52)
- Androgen regulation of lipogenesis. (2000) (51)
- Specificity and partial purification of a factor in spent media from Sertoli cell-enriched cultures that stimulates steroidogenesis in Leydig cells. (1986) (49)
- Androgen-induced Rhox homeobox genes modulate the expression of AR-regulated genes. (2010) (49)
- Secretion of steroids, growth factors, and cytokines by immortalized mouse granulosa cell lines. (1994) (49)
- Expression of Tubb3, a Beta-Tubulin Isotype, Is Regulated by Androgens in Mouse and Rat Sertoli Cells1 (2011) (48)
- Influence of coculture with Sertoli cells on steroidogenesis in immature rat Leydig cells (1990) (47)
- Identification of the Phosphatidic Acid Phosphatase Type 2a Isozyme as an Androgen-regulated Gene in the Human Prostatic Adenocarcinoma Cell Line LNCaP* (1998) (47)
- Proteins interacting with an androgen-responsive unit in the C3(1) gene intron (1993) (47)
- Feminizing testicular Leydig cell tumor: hormonal profile before and after unilateral orchidectomy. (1987) (46)
- Desensitization of cultured rat sertoli cells by follicle-stimulating hormone and by l-isoproterenol (1980) (45)
- Advances in Brief Role of the Phosphatidylinositol 3-Kinase / PTEN / Akt Kinase Pathway in the Overexpression of Fatty Acid Synthase in LNCaP Prostate Cancer Cells 1 (2002) (43)
- Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNCaP prostatic adenocarcinoma cells (1999) (42)
- Androgen and progestogen production in cultured interstitial cells derived from immature rat testis. (1982) (41)
- 4 Local control systems within the testis (1992) (41)
- Androgen Regulation of Stage-Dependent Cyclin D2 Expression in Sertoli Cells Suggests a Role in Modulating Androgen Action on Spermatogenesis1 (2005) (41)
- Genome-wide identification of AR-regulated genes translated in Sertoli cells in vivo using the RiboTag approach. (2014) (41)
- Androgens transcriptionally regulate the expression of cystatin-related protein and the C3 component of prostatic binding protein in rat ventral prostate and lacrimal gland. (1996) (40)
- Prostatic stromal cells and testicular peritubular cells produce similar paracrine mediators of androgen action. (1990) (40)
- Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production (1996) (39)
- Nandrolone decanoate does not enhance training effects but increases IGF-I mRNA in rat diaphragm. (2000) (38)
- The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice (2014) (37)
- Nucleus-associated steroid 5alpha-reductase activity and androgen responsiveness. A study in various organs and brain regions of rats. (1974) (37)
- Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP (1995) (37)
- Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal (2011) (37)
- Effect of long-term food restriction on pituitary sensitivity to cLHRH-I in broiler breeder females. (1998) (37)
- Cytokines derived from activated human mononuclear cells markedly stimulate transferrin secretion by cultured Sertoli cells. (1996) (37)
- Source of immunoreactive inhibin in the chicken ovary. (1992) (37)
- Indirect mechanisms and cascades of androgen action (1999) (37)
- A human gene encoding diazepam-binding inhibitor/acy1-CoA-binding protein: transcription and hormonal regulation in the androgen-sensitive human prostatic adenocarcinoma cell line LNCaP. (1996) (37)
- Identification of IL-6 as one of the important cytokines responsible for the ability of mononuclear cells to stimulate Sertoli cell functions (1997) (36)
- Characterization of the human secretory component gene promoter. (1996) (36)
- Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone. (2009) (35)
- Androgen regulation of the messenger RNA encoding diazepam-binding inhibitor/acyl-CoA-binding protein in the rat (1996) (35)
- Changes of immunoreactive inhibin, follicle-stimulating hormone, luteinizing hormone, and progesterone in plasma after short-term food deprivation and during the ovulatory cycle of the domestic hen. (1994) (34)
- Androgen-dependent expression of cystatin-related protein (CRP) in the exorbital lacrimal gland of the rat (1994) (34)
- Immunoreactive inhibin in plasma, amniotic fluid, and gonadal tissue of male and female chick embryos. (1992) (34)
- Permanent Effects of Foetal and Neonatal Testosterone Secretion on Steroid Metabolism and Binding (1973) (34)
- Intronic androgen response elements of prostatic binding protein genes. (1993) (33)
- Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development. (2010) (33)
- Lipase-based quantitation of triacylglycerols in cellular lipid extracts: Requirement for presence of detergent and prior separation by thin-layer chromatography (1997) (33)
- Biliary cirrhosis induces type IIx/b fiber atrophy in rat diaphragm and skeletal muscle, and decreases IGF-I mRNA in the liver but not in muscle. (1998) (32)
- Inhibin and activin have antagonistic paracrine effects on gonadal steroidogenesis during the development of the chicken embryo. (1996) (31)
- Heregulins or neu differentiation factors and the interactions between peritubular myoid cells and Sertoli cells. (1999) (30)
- Interaction of androgen and glucocorticoid receptor DNA-binding domains with their response elements (1993) (30)
- Androgen binding proteins in mouse submandibular gland. (1979) (29)
- Changes in immunoreactive FSH and inhibin in developing chicken embryos and the effects of estradiol and the aromatase inhibitor R76713. (1993) (29)
- Characterization of newly established testicular peritubular and prostatic stromal cell lines: potential use in the study of mesenchymal-epithelial interactions. (1995) (28)
- Regulation of Sertoli cell alpha 2-macroglobulin and clusterin (SGP-2) secretion by peritubular myoid cells. (1993) (28)
- Comparison of the Metabolism and Receptor Binding of Testosterone and 17β-Hydroxy-5α-Androstan-3-One in Normal Skin Fibroblast Cultures: Influence of Origin and Passage Number (1979) (27)
- A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene (2012) (27)
- A comparative study of androgen binding in rat uterus and prostate. (1976) (27)
- Human androgen receptor expressed in HeLa cells activates transcription in vitro. (1994) (26)
- The role of cell-cell interactions in androgen action (1992) (26)
- Interconversion between 17 beta-hydroxy-5alpha-androstan-3-one (5alpha-dihydrotestosterone) and 5alpha-androstane-3alpha, 17 beta-diol in rat kidney: heterogeneity of 3alpha-hydroxysteroid oxidoreductases. (1976) (26)
- Comparison of the 5' upstream putative regulatory sequences of three members of the alpha 2u-globulin gene family. (1987) (25)
- Hormonal control of phosphodiesterase activity in cultured rat sertoli cells (1981) (25)
- Developmental extinction of liver lipoprotein lipase mRNA expression might be regulated by an NF‐1‐like site (1993) (24)
- Apparent coactivation due to interference of expression constructs with nuclear receptor expression (2000) (24)
- A filter disc assay for the measurement and characterization of androgen-binding protein in unconcentrated media from Sertoli cell-enriched cultures. (1984) (24)
- Transferrin receptor expression in rat liver: Immunohistochemical and biochemical analysis of the effect of age and iron storage (1990) (23)
- Local control systems within the testis. (1992) (23)
- Testosterone receptors in the prostate and other tissues. (1975) (23)
- Androgen receptor in Sertoli cells is not required for testosterone-induced suppression of spermatogenesis, but contributes to Sertoli cell organization in Utp14b jsd mice. (2009) (22)
- Immunohistochemistry and in situ hybridization of the androgen receptor in the developing human prostate (1998) (21)
- Kallikrein-related protease in the rat ventral prostate: cDNA cloning and androgen regulation (1989) (21)
- Different cells and cell lines produce factors that modulate Sertoli cell function (1994) (21)
- Interconversion between 17β-hydroxy-5α-androstan-3-one (5α-dihydrotestosterone) and 5α-androstane-3α,17β-diol: Tissue specificity and role of the microsomal NAD: 3α-hydroxysteroid oxidoreductase (1977) (20)
- Systolic ventricular dysfunction causes selective diaphragm atrophy in rats. (1998) (20)
- Inhibitory effects of alkane sulphonates on the function of immature rat Leydig, Sertoli and peritubular cells cultured in vitro. (1989) (20)
- Desensitization of FSH-responsive adenylyl cyclase in cultured immature Sertoli cells by homologous hormone. (1982) (20)
- Intranuclear metabolism of testosterone in kidneys of male and female rats. (1971) (19)
- Mesenchymal entactin-1 (nidogen-1) is required for adhesion of peritubular cells of the rat testis in vitro. (2000) (19)
- Dimeric inhibin A and alpha-subunit immunoreactive material in maternal serum during spontaneous and in vitro fertilization pregnancies. (1996) (19)
- Kinetic data on the formation of 17 -hydroxy-5 -androstan-3-one in renal nuclei from male and female rats. (1972) (19)
- Both retinoids and androgens are required to maintain or promote functional differentiation in reaggregation cultures of human prostate epithelial cells (2002) (18)
- Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells (2006) (18)
- Contribution of the fetal adrenal to circulating immunoactive inhibin in the chicken embryo. (1994) (18)
- The development of an inducible androgen receptor knockout model in mouse to study the post-meiotic effects of androgens on germ cell development (2011) (18)
- Production of transferrin-like immunoreactivity by rat anterior pituitary and intermediate lobe. (1995) (18)
- Nuclear extracts enhance the interaction of fusion proteins containing the DNA-binding domain of the androgen and glucocorticoid receptor with androgen and glucocorticoid response elements (1994) (17)
- Prolonged exposure to androgens suppresses follicle-stimulating hormone-induced aromatase activity in rat Sertoli cell cultures (1988) (17)
- The dynamics of steroid and adenosine 3',5'-cyclic monophosphate output in perifused interstitial cell aggregates derived from prepubertal rat testes. (1986) (17)
- Stromal cells from the rat prostate secrete androgen-regulated factors which modulate Sertoli cell function (1989) (17)
- Ovarian and extraovarian sources of immunoreactive inhibin in the chicken: effects of dexamethasone. (1997) (17)
- Effect of androgens on the germ cell-depleted testes of prenatally irradiated rats. (1995) (16)
- Coactivation of an endogenous progesterone receptor by TIF2 in COS-7 cells. (2002) (16)
- INCREASED POSTOVULATORY PLASMA FOLLICLE STIMULATING HORMONE LEVELS IN THE LUTEINIZED UNRUPTURED FOLLICLE SYNDROME: A ROLE FOR INHIBIN? (1981) (16)
- Transcortin and alpha 2u-globulin messenger RNA activities during turpentine-induced inflammation in the rat. (1985) (15)
- Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice (2009) (15)
- Retinoids stimulate lipid synthesis and accumulation in LNCaP prostatic adenocarcinoma cells (1997) (15)
- Coactivator-Stimulated Gene Transcription Domain Plays a Key Role in p 160 The Androgen Receptor Amino-Terminal (1999) (15)
- Incidence, growth and oestradiol-receptor levels of 7, 12-dimethylbenz (alpha) anthracene-induced mammary tumours in rats: effects of neonatal sex steroids and oestradiol implants. (1982) (15)
- Antibodies against synthetic peptides recognize the human and rat androgen receptor (1990) (15)
- Sertoli cell androgen receptor signalling in adulthood is essential for post‐meiotic germ cell development (2015) (14)
- Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells. (2000) (14)
- Response of transcortin and alpha 2u-globulin to turpentine-induced inflammation in the rat: influence of corticosteroids and prolactin. (1983) (14)
- Organotypic Cultures of Prepubertal Mouse Testes: A Method to Study Androgen Action in Sertoli Cells while Preserving their Natural Environment (2009) (14)
- The retinoblastoma protein-associated transcription repressor RBaK interacts with the androgen receptor and enhances its transcriptional activity. (2003) (14)
- Androgens down-regulate the expression of the human homologue of Paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP (1999) (13)
- A Sertoli cell‐specific knock‐out of the androgen receptor (2005) (13)
- Contribution of Recent Transgenic Models and Transcriptional Profiling Studies to Our Understanding of the Mechanisms by which Androgens Control Spermatogenesis (2008) (13)
- Morphological and functional similarities between cultured prostatic stromal cells and testicular peritubular myoid cells (1991) (12)
- Gonadotrophin-regulated production of immunoactive inhibin and androgen by cultured testicular cells from chicken embryos. (1995) (12)
- Inhibition by a 4-methyl-4-aza-steroid of nadph: δ4-3-oxosteroid-5α-oxido-reductase activity in cultured interstitial cells derived from immature rat testis (1983) (11)
- Inhibin and steroid responses to testicular stimulation in normal men. (1995) (11)
- Interaction of estrogen receptor complexes with the promoter region of genes that are negatively regulated by estrogens: the alpha 2u-globulins. (1992) (11)
- Relationship between the pituitary gland and gonadal steroids: involvement of a hypophysial factor in reduced alpha 2u-globulin and increased transcortin concentrations in rat serum. (1978) (11)
- Effect of different methods of germinal cell destruction on rat testis. (1980) (11)
- Androgen and progestogen production by prepubertal rat interstitial cells: study of the effects of LHRH and its analogues and their interactions with LH (1984) (11)
- Evidence for the presence of immunoreactive inhibin in extragonadal tissues of ovariectomized ewes. (1997) (11)
- A comparative study of the androgen receptor apparatus in adult rodents. (1975) (10)
- The role of androgens in the control of spermatogenesis: lessons from transgenic models involving a Sertoli cell-selective knockout of the androgen receptor (2007) (10)
- [Androgens and increased lipogenesis in prostate cancer. Cell biologic and clinical perspectives]. (2002) (9)
- Expression of cystatin-related protein and of the C3-component of prostatic-binding protein during postnatal development in the rat ventral prostate and lacrimal gland (1998) (9)
- Influence of neonatal androgenization on the expression of alpha 2u-globulin in rat liver and submaxillary gland. (1985) (8)
- Effects of testosterone mediated or modulated by pituitary factors. (1975) (8)
- Functional Androgen Response Elements in the Genes Coding for Prostatic Binding Protein a (1993) (8)
- Tubule-Leydig cell interactions (1989) (8)
- Glucocorticoid receptor binding to defined regions of alpha 2u-globulin genes. (1987) (8)
- Dicyclohexane derivatives that bind to androgen-binding protein (ABP) also inhibit hormone stimulated aromatase activity in rat Sertoli cells. (1983) (8)
- α2‐Macroglobulin: A Multifunctional Protein of the Seminiferous Tubule a (1991) (7)
- Synthesis and processing of pre‐α2u‐globulin in different translational systems (1981) (7)
- Impairment of ovarian ovulatory function after tubal surgery in the rabbit (1980) (7)
- Rat tumor Leydig cells as a test system for the study of Sertoli cell factors that stimulate steroidogenesis. (1991) (7)
- Androgen binding in rat uterus cytosol. Study of the specificity. (1976) (7)
- Androgens and the testis. (1992) (7)
- Androgenic control of the microsomal 3α-hydroxysteroid oxidoreductases in rat kidney (1977) (7)
- Binding of androgen-receptor complexes to α2u-globulin genes and to the long terminal repeat of mouse mammary tumor virus (1989) (7)
- Androgen-regulated transcription in the epithelium of the rat lacrimal gland. (1998) (6)
- Role of the hypothalamo-hypophyseal axis in neonatal androgenisation and its postpubertal expression. (1977) (6)
- Heterogeneity of α2u‐globulin gene products in different translational systems, plasma and urine (1983) (6)
- Desensitization of Sertoli cell-enriched cultures by FSH, L-isoproterenol and glucagon. Influence on subsequent stimulation of 17 beta-estradiol production. (1986) (5)
- Biochemical characterization of the NADPH: 4-ene-3-ketosteroid 5 alpha-oxidoreductase in rat ovarian suspension cultures. (1979) (5)
- Pathogenesis of Benign Prostatic Hyperplasia: Potential Role of Mesenchymal — Epithelial Interactions (1994) (5)
- Effects and characterization of paracrine factors produced by human prostate stromal cells in bioassays using rat Sertoli cells, LNCaP tumor cells, and cultured prostate epithelial cells (2001) (5)
- Inhibin and steroid response to testicular stimulation with pure FSH (Metrodin) in infertile men with unilateral cryptorchidism (2009) (5)
- Nucleus-associated 5 -reductase activity in the rat. (1971) (4)
- THE EFFECT OF EPIDERMAL GROWTH FACTOR ON IN VITRO INHIBIN AND PROGESTERONEPRODUCTION IN CHICKEN GRANULOSA CELLS (1995) (4)
- Metabolism of testosterone and dihydrotestosterone in cultured rat hepatoma cells. (1975) (4)
- Alterations in gene expression in hamster diaphragm after emphysema and lung volume reduction surgery (2002) (4)
- Apoptosis of Prostate Cancer Cells Gene Induces Growth Inhibition α Acetyl-CoA-Carboxylase-Mediated Silencing of the − RNA Interference (2005) (4)
- Influence of neonatal androgenization on the response of alpha 2u-globulin to testosterone and dexamethasone in the rat. (1980) (4)
- Effect of embryonic 19-nortestosterone treatment and surgical bursectomy on plasma concentrations of reproductive hormones, on inhibin content in adrenals and gonads and on the histological appearance of the gonads in the young chicken. (2003) (4)
- Local interactions between tubular and interstitial compartment in the testis (1990) (4)
- Multiple binding sites for nuclear factors in the 5′-upstream region of two α 2u-globulin genes: Implications for hormone-regulated and tissue-specific control (1993) (3)
- ANDROGENS PROMOTE THE SECRETION OF FOLLICLE STIMULATING HORMONE INHIBITING FACTOR ‘INHIBIN’ BY SERTOLI CELL‐ENRICHED CULTURES (1982) (3)
- Stimulatory effects of antiviral adenosine analogs on steroidogenesis in Leydig cells. (1988) (3)
- Sexual difference in the effect of cyproterone acetate and glucocorticoids on alpha2u-globulin in gonadectomized rats. (1978) (3)
- Measurement of testosterone in plasma by competitive protein binding. (1969) (3)
- Comparison of the metabolism and receptor binding of testosterone and 17 beta-hydroxy-5 alpha-androstan-3-one in normal skin fibroblast cultures: influence of origin and passage number. (1979) (2)
- Circulating levels of inhibin and FSH during the oestrous cycle in 4 genotypes of sheep with different reproductive performances (1998) (2)
- A Fos-Jun element in the first intron of an α2u-globulin gene (1993) (2)
- Nuclear Extracts Enhance Gel Retardation with Androgen and Glucocorticoid Receptor DNA‐Binding Domains (1993) (2)
- Tissue-selective knockouts of steroid receptors: a novel paradigm in the study of steroid action. (2009) (2)
- Interconversion between 17beta-hydroxy-5alpha-androstan-3-one (5alpha-dihydrotestosterone) and 5alpha-androstane-3alpha,17beta-diol: tissue specificity and role of the microsomal NAD: 3alpha-hydroxysteroid oxidoreductase. (1977) (2)
- A Fos-Jun element in the first intron of an alpha 2u-globulin gene. (1993) (2)
- Organizing Effects of “Early” Testosterone Secretion on Steroid Metabolism and Binding (1973) (2)
- Characterisation of the human secretory component gene promoter. (1997) (2)
- Spermatogenesis and spermatogenic control: a state of the art. (1999) (2)
- Androgens Stimulate the SREBP Pathway in Prostate Cancer Cells by Inducing a Shift in the SCAP-Retention Protein(s) Balance (2005) (2)
- Steroid hormone secretion by stromal cells of pre- and postpubertal rat ovaries (1982) (1)
- 6B 2. Mechanism of action: Androgens—II 212. Androgen-binding in prostate and kidney as studied by ammonium sulfate precipitation (1974) (1)
- The androgen responsiveness of Sertoli cells depends on a complex interplay between androgens, FSH and peritubular cell factors (1988) (1)
- Nucleus-associated 5α-reductase activity in rat. Hormones and antagonists (1972) (1)
- Regulation de la secretion androgenique du testitule (1992) (1)
- Hepatic transferrin receptor expression in the carbonyl iron fed rat. An immunohistochemical and biochemical study (1989) (1)
- [Hormonal control of Sertoli cell function: effect of FSH, neurotransmitters and glucagon]. (1986) (1)
- Regulation of mechanisms of inhibin secretion (1984) (1)
- Alu sequences in the LDL receptor messenger RNA (1986) (1)
- Cancer Prevention by Green Tea via EGCG-Mediated Inhibition of Fatty Acid Synthase (2005) (1)
- Tissue-specific androgen receptor knockout models. novel tools in the study of androgen action (2008) (0)
- Age and iron induced changes in hepatic transferrin receptors (1990) (0)
- A COMPARATIVE STUDY OF THE ANDROGEN RECEPTOR APPARATUS IN ADULT RODENTS (1976) (0)
- Diversity of androgen effects in adulthood : a search for possible causes outside the effector apparatus of the target cells. (1975) (0)
- Isolation of rat alpha2u-globulin genes and homology of alpha2u-globulin-like sequences in different rat strains and in other animal species (1986) (0)
- Role of PI3-kinase/Akt pathway in the overexpression of fatty acid synthase in prostate cancer (2003) (0)
- Abstract: P159 THE ANDROGEN RECEPTOR IS INVOLVED IN GONADAL ATHEROPROTECTION IN BOTH MALE AND FEMALE MICE (2009) (0)
- Perifused reaggregation cultures, a new system for the study of the dynamics of steroid and cAMP output in interstitial cells: application to the effects of EGF (1986) (0)
- Androgens and the Lipogenic Switch in Prostate Cancer (2009) (0)
- Chemical inhibition of acetyl-CoA carboxylase, the rate-limiting enzyme of the fatty acid synthesis, induces growth arrest and cytotoxicity selectively in prostate cancer cells (2006) (0)
- Inhibition of tumor-associated lipogenesis changes membrane lipid composition and affects membrane structure and function (2008) (0)
- Isolation and characterization of a rat prostatic protease messenger-rna (1988) (0)
- Paracrine interactions between the interstitial and the tubular compartment of the testis. (1991) (0)
- 27. Androgen binding in rat uterus cytosol (1975) (0)
- [Simultaneous increase in the aromatization of testosterone into estrogens and secretion of inhibin by Sertoli cells in culture]. (1980) (0)
- Isolation of rat alpha 2u -globulin-like sequences in different rat strains and in other animal species (1986) (0)
- Influence of Neonatal androgenization on the Expression of α2U-Globulin Genes (1985) (0)
- 294 ACCELERATED ATHEROSCLEROSIS IN FEMALE MICE LACKING THE ANDROGEN RECEPTOR (2011) (0)
- Role of tumor-associated lipogenesis in the formation and composition of membrane microdomains (2006) (0)
- Cancer esearch or and Stem Cell Biology rrant Activation of Fatty Acid Synthesis Suppresses R ary Cilium Formation and Distorts Tissue Development (2010) (0)
- Androgens regulate expression of tubb3, a sertoli cell-specific beta-tubulin isotype (2009) (0)
- Inhibition by a 4-methyl-4-aza-steroid of NADPH: delta 4-3-oxosteroid-5 alpha-oxido-reductase activity in cultured interstitial cells derived from immature rat testis. (1983) (0)
- Desensitization of cultured rat Sertoli cells by follicle stimulating hormone and by ß-adrenergic agonists (1981) (0)
- Growth hormone and muscle function (2001) (0)
- Organotypic cultures of prepubertal mouse testes (2009) (0)
- The colorful world of androgen response elements (2008) (0)
- Glucose-independent activation of Carbohydrate Response Element Binding Protein contributes to enhanced lipogenesis and cell survival in prostate cancer cells (2009) (0)
- Androgenic control of themicrosomal 3alpha-hydroxysteroid oxidoreductases in rat kindey. (1977) (0)
- Tuberoinfundibular peptide of 39 residues: a neuromodulator starting a second career in the control of meiosis. (2008) (0)
- Non-steroidal Inhibitors of Steroid Interactions With Androgen-binding Proteins (1982) (0)
- Molecular genetics and lipid disorders: new perspectives in atherosclerosis (1987) (0)
- Sertoli cells from immature rat testes are capable of the metabolizing testosterone to 17ß-estradiol in the presence of follicle stimulating hormone (1982) (0)
- Androgen action on cortical bone surfaces requires a functional androgen receptor: Evidence from the androgen receptor knock-out mouse model (2005) (0)
- Squalene synthase: an androgen-regulated determinant of raft-associated cholesterol and modulator of prostate cancer cell proliferation (2006) (0)
- The androgen receptor is involved in gonadal atheroprotection in both male and female mice (2009) (0)
- Tumor-associated lipogenesis affects the lipid composition of detergent-resistant membrane microdomains (2004) (0)
- Silencing of the Fatty Acid Synthase Gene by RNA Interference Inhibits Growth and Induces Apoptosis of LNCaP Prostate Cancer Cells (2005) (0)
- The hormone-independent activation function 1 of the androgen receptor is the major recruiting surface for co-activators to androgen-specific enhancers (1999) (0)
- Alpha 2-macroglobulin: a multifunctional protein of the seminiferous tubule. (1991) (0)
- Perinatal origins of adult Leydig cells and function: role of developmental androgens (2013) (0)
- Significance of the intranuclear delta 4 -3-ketosteroid 5?-oxidoreductase as studied by the in vitro incubation of male and female rat kidney nuclei (1973) (0)
- Spermatogenesis, Endocrine Control of (2004) (0)
- INVITED LECTURE: Impact of AMPK activators on cancer cell biology: a multi-omics approach (2006) (0)
- Study of androgen binding in rat uterus (1977) (0)
- Androgenic effects on bone and body composition depend on concerted and additive activation of both AR and ER alpha: Evidence from a new male mouse model with combined disruption of both AR and ER alpha (2007) (0)
- INVITED LECTURE: Androgenic regulation of lipogenic gene expression in prostate cancer (2005) (0)
- Reproductive processes and contraception (1983) (0)
- Book reviewHormones and brain development: Series: Developments in endocrinology, Vol. 3 G. Dörner and M. Kawami (eds.) Elsevier/North-Holland Biomedical Press, Amsterdam-New York-Oxford, 1978 (473 + xiii pp., 147 figs., 63 tables) dfl. 44.00; US $ 64.00 (1980) (0)
- Androgen-dependent Sertoli cell proliferation as a target for endocrine disruptors relevant to human male reproductive health (2006) (0)
- Androgen regulation of spermatogenesis (2007) (0)
- Inhibition of tumor-associated lipogenesis changes membrane lipid composition and renders cancer cells more sensitive to chemotherapy-induced cell death (2008) (0)
- Synthesis and processing of pre-alpha 2u-globulin in different translational systems. (1981) (0)
- Endocrine control of tumor-associated lipogenesis (2003) (0)
- Kenneth W. McKERNS: Strukture and Function of the Gonadotropins. (2009) (0)
- B. B. Saxena, K.J. Catt, L. Birnbaumer and L. Martini: Hormone Receptors in Growth and Reproduction (2009) (0)
- Acetyl-CoA carboxylases are essential for the formation of detergent-resistant membrane microdomains (2007) (0)
- Heterogeneity of alpha 2u-globulin gene products in different translational systems, plasma and urine. (1983) (0)
- Physical Excercise Reduces Remodeling Imbalance and Preserves Trabecular Microarchitecture in Male Mice with Androgen Receptor Disruption (2006) (0)
- A transgenic model illustrates the importance of a second type of DNA binding by the androgen receptor for fertility and epididymis development (2009) (0)
- [Basic data on calcium metabolism]. (1973) (0)
- Cell-cell interactions in the regulation of testicular endocrine function (2006) (0)
- 240. Nonsteroidal inhibitors of androgen-binding protein (ABP) decrease rat sertoli cell aromatase activity in response to follicle-stimulating hormone (1982) (0)
- Dihydrotestosterone, Active Androgen Metabolites and Related Pathology (2003) (0)
- Sexual differentiation of the metabolism ande intra-cellular binding of steroid hormones (1973) (0)
- Contents, Vol. 2, 1971/72 (1971) (0)
- Androgen secretion by the stromal cell of the rat ovary (1983) (0)
- Androgen action in the testis (2010) (0)
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