Günter j. Hämmerling

Günter j. Hämmerling's AcademicInfluence.com Rankings

Biology

#8801

World Rank

#11933

Historical Rank

Immunology

#510

World Rank

#527

Historical Rank

biology Degrees

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Biology

Günter j. Hämmerling's Degrees

PhD Immunology University of California, Berkeley
Doctorate Medicine Stanford University

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Günter j. Hämmerling's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy. (2013) (746)
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) (2019) (627)
Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. (1993) (608)
T Cell Awareness of Paternal Alloantigens During Pregnancy (1995) (567)
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction (1991) (565)
Vascular normalization in Rgs5-deficient tumours promotes immune destruction (2008) (516)
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis. (2016) (420)
Abrogation of metastatic properties of tumour cells by de novo expression of H–2K antigens following H–2 gene transfection (1985) (410)
Selectivity of MHC-encoded peptide transporters from human, mouse and rat (1994) (374)
Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. (2002) (350)
A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter. (1997) (345)
Bone marrow as a priming site for T-cell responses to blood-borne antigen (2003) (340)
Immunohistochemical study of the expression of a Mr 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues. (1987) (336)
Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8+ T cells (2015) (335)
Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein. (1998) (316)
Editing of the HLA‐DR‐peptide repertoire by HLA‐DM. (1996) (303)
Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line (2001) (299)
CD11c depletion severely disrupts Th2 induction and development in vivo (2010) (292)
Resistance of young gelatinase B-deficient mice to experimental autoimmune encephalomyelitis and necrotizing tail lesions. (1999) (274)
Induced bronchus-associated lymphoid tissue serves as a general priming site for T cells and is maintained by dendritic cells (2009) (264)
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation (1992) (258)
Autoimmune diabetes as a consequence of locally produced interleukin-2 (1992) (255)
Subunit of the '20S' proteasome (multicatalytic proteinase) encoded by the major histocompatibility complex (1991) (253)
Levels of peripheral T cell tolerance induced by different doses of tolerogen. (1994) (252)
Chemokines direct endothelial progenitors into tumor neovessels. (2005) (249)
ER‐60, a chaperone with thiol‐dependent reductase activity involved in MHC class I assembly (1998) (236)
Peptide size selection by the major histocompatibility complex-encoded peptide transporter (1994) (233)
NK- and CD8+ T Cell-Mediated Eradication of Established Tumors by Peritumoral Injection of CpG-Containing Oligodeoxynucleotides1 (2001) (232)
HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH. (1997) (230)
Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57 (2006) (227)
Impaired immune responses and altered peptide repertoire in tapasin-deficient mice (2000) (216)
Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease (2011) (212)
Multiple levels of peripheral tolerance. (1993) (209)
ERp57 is essential for efficient folding of glycoproteins sharing common structural domains (2007) (200)
Regulator of G-protein signaling-5 induction in pericytes coincides with active vessel remodeling during neovascularization. (2005) (195)
A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells (2008) (186)
Localization of allodeterminants on H-2Kb antigens determined with monoclonal antibodies and H-2 mutant mice. (1982) (185)
Systemic application of CpG‐rich DNA suppresses adaptive T cell immunity via induction of IDO (2006) (176)
Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies (1979) (166)
Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel. (2000) (164)
Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling (1994) (162)
Translocation of long peptides by transporters associated with antigen processing (TAP) (1996) (158)
Ia invariant chain detected on lymphocyte surfaces by monoclonal antibody (1982) (152)
Boosting Regulatory T Cells Limits Neuroinflammation in Permanent Cortical Stroke (2013) (152)
Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2. (2011) (151)
Control of neonatal tolerance to tissue antigens by peripheral T cell trafficking. (1998) (151)
Cross‐presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance (2005) (150)
Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum. (1996) (150)
Differential expression of Ia and Ia-associated invariant chain in mouse tissues after in vivo treatment with IFN-gamma. (1986) (148)
Loss of HLA‐A,B,C and de novo expression of HLA‐D in colorectal cancer (1986) (146)
A role for HLA‐DO as a co‐chaperone of HLA‐DM in peptide loading of MHC class II molecules (1998) (143)
HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA- DRB1*0301 (DR3) gene (1996) (141)
Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen. (1992) (140)
Temporal Cre‐mediated recombination exclusively in endothelial cells using Tie2 regulatory elements (2002) (139)
CpG Motifs as Proinflammatory Factors Render Autochthonous Tumors Permissive for Infiltration and Destruction1 (2004) (139)
Failure to induce organ‐specific autoimmunity by breaking of tolerance: importance of the microenvironment (1998) (139)
Epithelium-specific surface glycoprotein of Mr 34,000 is a widely distributed human carcinoma marker. (1987) (138)
Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice (2012) (136)
Dendritic Cells Support Homeostatic Expansion of Foxp3+ Regulatory T Cells in Foxp3.LuciDTR Mice (2010) (133)
Recruitment of MHC Class I Molecules by Tapasin into the Transporter Associated with Antigen Processing-Associated Complex Is Essential for Optimal Peptide Loading (2002) (130)
How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest? (1997) (129)
The endoplasmic reticulum‐resident stress protein gp96 binds peptides translocated by TAP (1997) (128)
A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression (2003) (127)
Generation, intracellular transport and loading of peptides associated with MHC class I molecules. (1997) (119)
Consequences of ERp57 Deletion on Oxidative Folding of Obligate and Facultative Clients of the Calnexin Cycle* (2006) (119)
Modulation of NKp30- and NKp46-Mediated Natural Killer Cell Responses by Poxviral Hemagglutinin (2011) (117)
Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy (2009) (116)
Efficient Treg depletion induces T‐cell infiltration and rejection of large tumors (2010) (116)
Idiotypic analysis of lymphocytes in vitro. I. Specificity and heterogeneity of B and T lymphocytes reactive with anti-idiotypic antibody (1976) (116)
Generation and TAP-mediated transport of peptides for major histocompatibility complex class I molecules. (1998) (116)
Self-Release of CLIP in Peptide Loading of HLA-DR Molecules (1995) (115)
Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM. (1996) (114)
Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site. (1996) (114)
Selective loss of HLA-A or HLA-B antigen expression in colon carcinoma. (1989) (113)
Analysis of the fine specificity of rat, mouse and human TAP peptide transporters (1995) (111)
CD80 and CD86 Differentially Regulate Mechanical Interactions of T-Cells with Antigen-Presenting Dendritic Cells and B-Cells (2012) (107)
Peptide selection by MHC-encoded TAP transporters. (1994) (107)
Peripheral Tolerance as a Multi‐Step Mechanism (1993) (105)
Organization and evolution of D region class I genes in the mouse major histocompatibility complex (1986) (105)
Human cytomegalovirus inhibits peptide translocation into the endoplasmic reticulum for MHC class I assembly. (1996) (104)
A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival (2010) (104)
Anergy induced by thymic medullary epithelium (1992) (102)
Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen (2010) (102)
Remote control of tumour‐targeted Salmonella enterica serovar Typhimurium by the use of l‐arabinose as inducer of bacterial gene expression in vivo (2007) (100)
Transformation of the microvascular system during multistage tumorigenesis (2002) (99)
The impact of the non‐classical MHC proteins HLA‐DM and HLA‐DO on loading of MHC class II molecules (1999) (99)
Cutting Edge: IL-7-Dependent Homeostatic Proliferation of CD8+ T Cells in Neonatal Mice Allows the Generation of Long-Lived Natural Memory T Cells 1 (2004) (97)
TAP polymorphism does not influence transport of peptide variants in mice and humans (1995) (95)
HLA-DM, HLA-DO and tapasin: functional similarities and differences. (2002) (94)
Strong xenogeneic HLA response in transgenic mice after introducing an α3 domain into HLA B27 (1990) (94)
High TCR diversity ensures optimal function andhomeostasis of Foxp3+ regulatory Tcells (2011) (92)
Cross‐blocking studies with monoclonal antibodies against I‐A molecules of haplotypes b, d and k (1982) (91)
Functional HLA‐DM on the surface of B cells and immature dendritic cells (2000) (90)
On the structure of the T-cell receptor for antigen. (1977) (90)
Chronic Helminth Infection Promotes Immune Regulation In Vivo through Dominance of CD11cloCD103− Dendritic Cells (2011) (89)
Commensal microflora and interferon‐γ promote steady‐state interleukin‐7 production in vivo (2010) (88)
Cross‐presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor‐specific CD8+ T cell tolerance (2006) (88)
A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity (1996) (82)
Idiotypic analysis of lymphocytes in vitro. II. Genetic control of T- helper cell responsiveness to anti-idiotypic antibody (1976) (81)
Intestinal Cell Calcium Uptake and the Targeted Knockout of the 1,25D3-MARRS (Membrane-associated, Rapid Response Steroid-binding) Receptor/PDIA3/Erp57* (2010) (80)
ER60/ERp57 forms disulfide‐bonded intermediates with MHC class I heavy chain (2001) (79)
Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide (1993) (79)
Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma. (2006) (79)
Influence of major histocompatibility complex class I and II antigens on survival in colorectal carcinoma. (1991) (78)
Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing. (1996) (78)
The influence of major histocompatibility complex class I antigens on tumor growth and metastasis. (1987) (76)
Mini‐review: Overcoming tumor‐intrinsic resistance to immune effector function (2004) (75)
Antigen presentation of hen egg‐white lysozyme but not of ribonuclease A is augmented by the major histocompatibility complex class II‐associated invariant chain (1991) (74)
Control of Uterine Microenvironment by Foxp3+ Cells Facilitates Embryo Implantation (2013) (73)
Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the αIIbβ3 integrin. (2013) (73)
Restoration of a tumorigenic phenotype by beta 2-microglobulin transfection to EL-4 mutant cells (1992) (73)
Antigen binding T and B lymphocytes. I. Differences in cellular specificity and influence of metabolic activity on interaction of antigen with T and B cells. (1974) (72)
Monoclonal antibodies against murine cell surface antigens: anti-H-2, anti-Ia and anti-T cell antibodies. (1978) (69)
Type 2 Innate Immunity in Helminth Infection Is Induced Redundantly and Acts Autonomously following CD11c+ Cell Depletion (2012) (68)
Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice. (2008) (65)
Cellular Regulation of the Uterine Microenvironment That Enables Embryo Implantation (2015) (65)
Tissue distribution of Ia antigens and their expression on lymphocyte subpopulations. (1976) (64)
Exogenous peptides compete for the presentation of endogenous antigens to major histocompatibility complex class II-restricted T cells (1991) (64)
Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells. (2017) (62)
A Transporter Associated with Antigen-Processing Independent Vacuolar Pathway for the MHC Class I-Mediated Presentation of Endogenous Transmembrane Proteins (2007) (62)
Induction of assembly of MHC class I heavy chains with beta 2microglobulin by interferon‐gamma. (1989) (62)
TNF-induced target cell killing by CTL activated through cross-presentation. (2012) (60)
Transfection of beta 2-microglobulin restores IFN-mediated protection from natural killer cell lysis in YAC-1 lymphoma variants. (1990) (60)
Negative and positive selection by HLA-DR3(DRw17) molecules in transgenic mice (2004) (59)
CD11c+ Dendritic Cells and B Cells Contribute to the Tumoricidal Activity of Anti-DR5 Antibody Therapy in Established Tumors (2010) (59)
Myelin-Reactive, TGF-β–Induced Regulatory T Cells Can Be Programmed To Develop Th1-Like Effector Function but Remain Less Proinflammatory Than Myelin-Reactive Th1 Effectors and Can Suppress Pathogenic T Cell Clonal Expansion In Vivo (2010) (59)
Cutting Edge: Innate Immune Cells Contribute to the IFN-γ-Dependent Regulation of Antigen-Specific CD8+ T Cell Homeostasis1 (2006) (58)
Epitope-specific enhancement of antigen presentation by invariant chain (1993) (57)
Intracellular distribution of the MHC class II molecules and the associated invariant chain (Ii) in different cell lines. (1993) (57)
Long life span of tolerant T cells and the role of antigen in maintenance of peripheral tolerance. (1995) (56)
Processing of an endogenous protein can generate MHC class II-restricted T cell determinants distinct from those derived from exogenous antigen. (1991) (56)
Interference of distinct invariant chain regions with superantigen contact area and antigenic peptide binding groove of HLA-DR. (1995) (56)
Depletion of Dendritic Cells Enhances Innate Anti-Bacterial Host Defense through Modulation of Phagocyte Homeostasis (2012) (55)
Antigen binding T and B lymphocytes. II. Studies on the inhibition of antigen binding to T and B cells by anti-immunoglobulin and anti-H-2 sera. (1974) (55)
Monoclonal antibodies and T-cell hybridomas. Perspectives and technical advances. (1981) (55)
Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction. (1993) (54)
Alloreactive cytolytic T-cell clones preferentially recognize conformational determinants on histocompatibility antigens: analysis with genetically engineered hybrid antigens. (1985) (53)
IFN-γ Receptor Signaling Regulates Memory CD8+ T Cell Differentiation (2010) (53)
Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding. (1995) (53)
Interaction of ERp57 and tapasin in the generation of MHC class I-peptide complexes. (2007) (53)
Targeted Liposomal Delivery of TLR9 Ligands Activates Spontaneous Antitumor Immunity in an Autochthonous Cancer Model1 (2009) (51)
Mechanical Interactions between Dendritic Cells and T Cells Correlate with T Cell Responsiveness (2011) (51)
Continuous production of monoclonal mouse IgE antibodies with known allergenic specificity by a hybrid cell line (1978) (50)
Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin‐2 expression in peri‐tumourous liver correlates with increased survival (2013) (50)
Quantitative comparison of click beetle and firefly luciferases for in vivo bioluminescence imaging. (2007) (49)
Homeostasis of dendritic cells in lymphoid organs is controlled by regulation of their precursors via a feedback loop. (2009) (48)
Tonic T cell signalling and T cell tolerance as opposite effects of self-recognition on dendritic cells. (2010) (48)
Processing of endogenously synthesized hen egg-white lysozyme retained in the endoplasmic reticulum or in secretory form gives rise to a similar but not identical set of epitopes recognized by class II-restricted T cells. (1993) (48)
Reconstitution of H‐2 class I expression by gene transfection decreases susceptibility to natural killer cells of an EL4 class I loss variant (1990) (48)
Genetic control of the immune response. Frequency and characteristics of antigen-binding cells in high and low responder mice. (1973) (48)
The relationship between MHC antigen expression and metastasis. (1989) (47)
TAP2‐defective RMA‐S cells present Sendai virus antigen to cytotoxic T lymphocytes (1993) (47)
Accessory molecules in the assembly of major histocompatibility complex class I/peptide complexes: how essential are they for CD8+ T‐cell immune responses? (2005) (46)
Isolation of twelve monoclonal antibodies against Ia and H-2 antigens. Serological characterization and reactivity with B and T lymphocytes (1979) (46)
Resistance to natural killer cell lysis conferred by TAP1/2 genes in human antigen-processing mutant cells. (1994) (46)
The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics (1997) (46)
Autoaggression and tumor rejection: it takes more than self‐specific T‐cell activation (1999) (45)
The function of the invariant chain in antigen presentation by MHC class II molecules. (1990) (45)
Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance (2012) (44)
H-2-restricted antigen binding by a hybridoma clone that produces antigen-specific helper factor. (1981) (43)
The role of surface HLA-A,B,C molecules in tumour immunity. (1992) (42)
Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation (2014) (41)
Immune Evasion by Yersinia enterocolitica: Differential Targeting of Dendritic Cell Subpopulations In Vivo (2010) (41)
Identification of destabilizing residues in HLA class II‐selected bacteriophage display libraries edited by HLA‐DM (1999) (41)
CD8+ regulatory T cells generated by neonatal recognition of peripheral self-antigen (2006) (40)
Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection (2016) (39)
Biochemical characterization of Ia antigens. I. Characterization of the 31K polypeptide associated with I-A subregion Ia antigens. (1980) (39)
MHC class-I transgenic mice. (1991) (39)
Structure of the murine Ia‐associated invariant (Ii) chain as deduced from a cDNA clone. (1984) (39)
CD82 Restrains Pathological Angiogenesis by Altering Lipid Raft Clustering and CD44 Trafficking in Endothelial Cells (2014) (39)
Tissue distribution of ia antigens: Ia on spermatozoa, macrophages, and epidermal cells (1974) (38)
LOSS OF HLA‐A,B,C IN COLORECTAL CARCINOMA IS RELATED TO THE DEGREE OF DE‐DIFFERENTIATION (1986) (38)
Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver (1999) (38)
Innate immune cells contribute to the IFN-gamma-dependent regulation of antigen-specific CD8+ T cell homeostasis. (2006) (38)
In vivo induction of H‐2K/D antigens by recombinant interferon‐γ (1986) (37)
Mitomycin C-treated dendritic cells inactivate autoreactive T cells: Toward the development of a tolerogenic vaccine in autoimmune diseases (2008) (37)
One gene encodes two distinct Ia-associated invariant chains. (1985) (37)
Review of murine dendritic cells: types, location, and development. (2010) (36)
Poor loading of major histocompatibility complex class II molecules with endogenously synthesized short peptides in the absence of invariant chain (1995) (36)
Interleukin-7 Links T Lymphocyte and Intestinal Epithelial Cell Homeostasis (2012) (35)
The HLA-D-associated invariant chain binds palmitic acid at the cysteine adjacent to the membrane segment. (1986) (34)
How HLA-DM affects the peptide repertoire bound to HLA-DR molecules. (1997) (34)
Tolerance induction as a multi‐step process (1994) (34)
Organ-Specific Cellular Requirements for In Vivo Dendritic Cell Generation (2012) (31)
Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells. (2011) (30)
Structure of Ia antigens: identification of dimeric complexes formed by the invariant chain. (1982) (30)
HLA-DM stabilizes empty HLA-DR molecules in a chaperone-like fashion. (1997) (28)
Quality control of MHC class II associated peptides by HLA-DM/H2-M. (1999) (28)
Vascular Integration of Endothelial Progenitors During Multistep Tumor Progression (2006) (27)
Tetraspanin microdomains control localized protein kinase C signaling in B cells (2017) (27)
H-2-restricted helper factor secreted by clone hybridoma cells (1981) (26)
T cell-dependent protective effects of CpG motifs of bacterial DNA in experimental colitis are mediated by CD11c+ dendritic cells (2010) (26)
Threshold tolerance in H-2Kb-specific TCR transgenic mice expressing mutant H-2Kb: conversion of helper-independent to helper-dependent CTL. (1992) (26)
Heat shock protein-antigen fusions lose their enhanced immunostimulatory capacity after endotoxin depletion. (2008) (25)
Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire (2010) (25)
Serological analysis of H-2 and Ia molecules with monoclonal antibodies (1979) (25)
Major histocompatibility complex class I genes in murine fibrosarcoma IC9 are down regulated at the level of the chromatin structure (1989) (24)
Control of peripheral T-lymphocyte tolerance in neonates and adults. (2005) (24)
Ir GENES AND ANTIGEN RECOGNITION1 (1974) (24)
Altered regulation of MHC class I genes in different tumor cell lines is reflected by distinct sets of DNase I hypersensitive sites. (1989) (24)
Regulation and Functional Role of MHC Expression on Tumors (1989) (23)
Cytotoxic T lymphocyte recognition of HLA‐A2 antigens in normal and HLA‐Cw3‐transgenic mice (1989) (23)
Antigen presentation in Syrian hamster cells: substrate selectivity of TAP controlled by polymorphic residues in TAP1 and differential requirements for loading of H2 class I molecules (1999) (22)
Comparison of alloantisera and hybridoma antibody for purification of the H-2Db murine histocompatibility antigen and preliminary molecular characterization of this antigen. (1980) (22)
Expression of la determinants on immunocompetent cells (1976) (21)
Characterization of a Human B Lymphocyte-Specific Antigen Defined by Monoclonal Antibodies HD6 and HD39 (1986) (20)
Two separate genes regulate self-Ia and carrier recognition in H-2- restricted helper factors secreted by hybridoma cells (1981) (20)
Function, target-cell preference and cell-surface characteristics of herpes-simplex virus type-2-induced non-antigen-specific killer cells. (1981) (20)
Cutting Edge: Innate Lymphoid Cells Suppress Homeostatic T Cell Expansion in Neonatal Mice (2016) (20)
A novel CD 11 c . DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells (2008) (19)
Irradiation and IL-15 promote loss of CD8 T-cell tolerance in response to lymphopenia. (2010) (19)
Tumor agonist peptides break tolerance and elicit effective CTL responses in an inducible mouse model of hepatocellular carcinoma. (2009) (19)
Analysis of V gene expression in the immune response by cell fusion. (1978) (18)
Retrotranslocation of MHC class I heavy chain from the endoplasmic reticulum to the cytosol is dependent on ATP supply to the ER lumen. (2004) (18)
Strong xenogeneic HLA response in transgenic mice after introducing an alpha 3 domain into HLA B27. (1990) (18)
Binding affinity independent contribution of peptide length to the stability of peptide-HLA-DR complexes in live antigen presenting cells. (1998) (18)
Intestinal cell phosphate uptake and the targeted knockout of the 1,25D3-MARRS receptor/PDIA3/ERp57. (2012) (17)
Evidence of a diverse T cell receptor repertoire for acetylcholine receptor, the autoantigen of myasthenia gravis. (2003) (17)
Fine Tuning of the Threshold of T Cell Selection by the Nck Adapters (2010) (17)
Ia-associated invariant chain is fatty acylated before addition of sialic acid. (1985) (16)
Idiotypic relationship of anti‐Ia.2 antibodies (1982) (15)
Independent control of natural killer cell responsiveness and homeostasis at steady-state by CD11c+ dendritic cells (2016) (15)
Co-dominant restriction by a mixed-haplotype I-A molecule (alpha k beta b) for the lysozyme peptide 52-61 in H-2k x H-2b F1 mice. (1990) (14)
Selection of the MHC Class II-associated peptide repertoire by HLA-DM (1997) (14)
The gene encoding the Ia-Associated invariant chain is located on chromosome 18 in the mouse (2004) (13)
Differential effect of transporter Tap 2 gene introduction into RMA‐S cells on viral antigen processing (1993) (12)
Discordant differentiation antigen pattern in a case of Richter's syndrome with monoclonal idiotype expression and immunoglobulin gene rearrangement. (1990) (12)
A two-step model for the induction of organ-specific autoimmunity. (1998) (12)
Extrathymic T-cell selection (1992) (12)
HLA antibody responses in HLA class I transgenic mice (1990) (11)
Self-Antigen Presentation by Keratinocytes in the Inflamed Adult Skin Modulates T-Cell Auto-Reactivity. (2015) (11)
Monoclonal antibodies detect polymorphic determinants shared by I-A and I-E antigens. (1984) (10)
Elicitation of delayed-type hypersensitivity to phosphorylcholine by monoclonal anti-idiotypic antibodies in an allogeneic environment (1982) (10)
Nomenclature for H-2 and Ia antigens defined by monoclonal antibodies (1979) (10)
Genetic control of the immune response: ability of antigens of defined amino acid sequence to be recognized by the Ir‐1 gene system (1976) (10)
Anti‐idiotypes against anti‐H−2 antibodies VI. Detection of shared idiotypes among monoclonal anti‐H−2 antibodies (1983) (9)
Monoclonal Antibodies to Idiotype Inhibit In Vitro Growth of Human B-Cell Lymphomas (1992) (9)
Characterization and functional analysis of T cell hybrids. (1978) (8)
Target sites for antibodies and cytotoxic T lymphocytes on H-2 molecules. (1983) (8)
Experimental autoimmune encephalomyelitis in mice expressing the autoantigen MBP 1-10 covalently bound to the MHC class II molecule I-Au. (2006) (8)
CELLULAR EXPRESSION OF Ia ANTIGENS AND THEIR POSSIBLE ROLE IN IMMUNE REACTIONS (1976) (7)
DEMONSTRATION OF T CELL SPECIFIC Ia ANTIGENS CODED FOR BY THE I-J SUBREGION ON IDIOTYPIC SUPPRESSOR T CELLS (1978) (7)
Histocompatibility-linked genetic control of specific immune responses. (1974) (7)
DIFFERENTIAL EXPRESSION OF Ia ANTIGENS ON SUPPRESSOR T CELLS, HELPER T CELLS AND B PRECURSOR CELLS (1976) (6)
TAP Peptide Transporters and Antigen Presentation (1996) (6)
Extrathymic T-cell selection. (1992) (6)
The coming of transgenic mice: tolerance and immune reactivity. (1990) (5)
Peptide binding and editing: generation of TCR ligands. (1998) (5)
Peptide transporters and antigen processing. (1994) (5)
Peripheral T Cell Tolerance: Distinct Levels and Multistep Mechanisms (1994) (5)
Distinct mechanisms of peripheral tolerance in transgenic mice. (1991) (5)
Ia antigens contain two distinct forms of β chain (2004) (5)
Structural comparison of I-A antigens produced by a cloned murine T suppressor cell line with B-Cell-Derived I-A (2004) (5)
Unrestricted recognition of class I neodeterminants generated by exon shuffling (1986) (5)
IFN-g Receptor Signaling Regulates Memory CD8 T Cell Differentiation (2010) (5)
Serological analysis of B6.C‐H‐2bm12 (I‐A mutant) (1982) (5)
Analysis of Ten B Lymphocyte-Specific Workshop Monoclonal Antibodies (1986) (4)
Separation of H-2Dd, H-2Ld, and H-2Rd by two-dimensional gel electrophoresis (2004) (4)
Flt3 ligand‐eGFP‐reporter expression characterizes functionally distinct subpopulations of CD150+ long‐term repopulating murine hematopoietic stem cells (2017) (4)
ANTIGEN RECEPTORS ON MOUSE T LYMPHOCYTES (1978) (4)
How HLA-DM edits the HLA-DR:peptide repertoire (1997) (4)
Monoclonal antibodies to idiotype inhibit in vitro growth of human B-cell lymphomas. (1992) (4)
The isolation of thirteen cloned hybrid cell lines secreting mouse strain A derived antibodies with specificity for group A streptococcal carbohydrate. (1978) (4)
O496 - Residues in TAP peptide transporters controlling substrate specificity (1996) (4)
Role of tapasin in MHC class I antigen presentation in vivo. (2001) (4)
Render Autochthonous Tumors Permissive CpG Motifs as Proinflammatory Factors (2004) (3)
Corrigendum: Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8+ T cells (2016) (3)
Frequency and characteristics of antigen binding cells in genetic high and low responder mice. (1973) (3)
The Role of Defective MHC Class I Expression for Tumor Growth and Metastasis (1987) (3)
Evidence that Ia-antigens are not secreted by antigen or mitogen stimulated mouse or guinea pig lymphocytes. (1978) (3)
Tolerance induction in mature T lymphocytes. (1998) (3)
Gene Products of the Major Histocompatibility Complex Control the Metastatic Phenotype of Tumor Cells (1986) (3)
The 1996 Nobel Prize to Rolf Zinkernagel and Peter Doherty (1996) (3)
T LYMPHOCYTE RECEPTOR ANALYSIS BY ANTI – IDIOTYPIC STIMULATION (1976) (3)
Ia associated Ii chain is not encoded by chromosome 17 of the mouse (2004) (3)
The nature and site of action of the Ir-1 gene. (1974) (2)
20 – Frequency, Regulation, and H-2 Epitope Specificity of Alloreactive and H-2-Restricted CTL Clones (1982) (2)
Model Immunity in an Autochthonous Cancer Ligands Activates Spontaneous Antitumor Targeted Liposomal Delivery of TLR 9 (2009) (2)
Genetic Control of T and B Cell Receptor Specificity in the Mouse (1976) (2)
Monoclonal Antibody (HD 39) Reactive with a Human B Lymphocyte Specific Antigen Expressed on Late Stages of B Cell Maturation (1985) (2)
Stimulation of autoimmunity by toll-like receptor ligands (2005) (2)
Factors, receptors, and their ligands: studies with H-2 restricted helper hybridoma clones (1982) (2)
Different genomic structure of mouse and human Lmp7 genes: characterization of MHC-encoded proteasome genes (1993) (2)
Metastasis of prostate cancer and melanoma cells in a preclinical in vivo mouse model is enhanced by L-plastin expression and phosphorylation (2014) (1)
Mechanical insights into the functional impacts of interactions between antigen-presenting cells and T cells (P5081) (2013) (1)
Peripheral T-cell tolerance in transgenic mouse models (1993) (1)
Induction of tolerance in mature peripheral T cells. (1993) (1)
Resistance to NK and metastatic potential of fibrosarcoma cells is associated with products encoded by the H-2D region. (1991) (1)
Antigen-binding structures on the surface of T lymphocytes. (1975) (1)
Flt 3 ligand-eGFP-reporter expression characterizes functionally distinct subpopulations of CD 150 + long-term repopulating murine hematopoietic stem cells (2017) (1)
Research on Diagnosis and Therapy (1986) (1)
Innate type 2 immunity in helminth infection is induced redundantly and acts autonomously following CD 11 c + cell depletion (2012) (1)
Molecular Heterogeneity of Ia Antigengs: Novel Components and Complexes (1983) (0)
A role for HLA-DO in peptide loading of HLA-DR molecules (1997) (0)
Endothelial Cells CD 82 Restrains Angiogenesis by Altering Lipid Raft Clustering and CD 44 Trafficking in (2014) (0)
Inactivation of the transporter associated with antigen processing (TAP) by a viral ER-resident glycoprotein (1997) (0)
Essential for Optimal Peptide Loading Antigen Processing-Associated Complex Is Tapasin into the Transporter Associated with Recruitment of MHC Class I Molecules by (2002) (0)
Antigen Binding T and B Lymphocytes (1974) (0)
Tolerance induction to peripheral antigens in the adult (1997) (0)
Impaired long bone growth in chondrocyte-specific ERp57 knockout mice is induced by ER stress (2015) (0)
Diagnostik- und Therapieforschung (1986) (0)
Mechanisms of Extrathymic Tolerance (1993) (0)
Antibodies to polymorphic HLA class I epitopes in HLA-transgenic mice (1989) (0)
H-2-restricted helper hybridomas: one locus or two control dual specificity? (1982) (0)
Bispecific antibodies direct specific lysis of carcinoma cells by activated T lymphocytes (1997) (0)
A novel non-MHC-I restricted CTL effector function mediated by TNF and XIAP (2011) (0)
Monoclonal Antibodies Against Murine Ia Antigens: Studies On Structure, Function, Epitopes, And Idiotypes (2019) (0)
The Influence of Murine and Human Major Histocompatibility Complex Class I Expression on Tumor Growth and Metastasis (1989) (0)
IDIOTYPIC IDENTITY OF STREP. A SPECIFIC ANTIGEN RECOGNITION SITES ON MOUSE T AND B-LYMPHOCYTES (1976) (0)
Abstract B79: Tumor rejection driven by efficient Treg depletion is associated with a strong change in the tumor microenvironment. (2013) (0)
Edinburgh Explorer Innate type 2 immunity in helminth infection is induced redundantly and acts autonomously following CD11c+ cell depletion (2018) (0)
The Role of Major Histocompatibility Complex Class I Antigens in Antitumor Immunity (1986) (0)
Fusion of Myeloma Cells with Mouse Lymphocytes (1977) (0)
Identification of destabilizing residues in an HLA-DM selected M13-displayed peptide repertoire (1997) (0)
Natural Memory T Cells Mice Allows the Generation of Long-Lived T Cells in Neonatal + Proliferation of CD8 Cutting Edge: IL-7-Dependent Homeostatic (2003) (0)
This information is current as Selection by the Nck Adapters Fine Tuning of the Threshold of T Cell (2010) (0)
Antigen presentation by MHC class II molecules : Role of the accessory MHC molecules HLA-DM and HLA-DO ( G 0400-2 ) (2003) (0)
This information is current as Responsiveness Cells and T Cells Correlate with T Cell Mechanical Interactions between Dendritic (2011) (0)
Oligodeoxynucleotides Injection of CpG-Containing of Established Tumors by Peritumoral T Cell-Mediated Eradication + NK-and CD 8 (2001) (0)
Induction and Breaking of Peripheral Tolerance (1996) (0)
PLATELETS AND THROMBOPOIESIS Platelet-derived ERp57 mediates platelet incorporation into a growing thrombus by regulation of the a IIb b 3 integrin (2013) (0)
Imaging immunity (2009) (0)
CD82 Restrains Angiogenesis by Altering Lipid Raft Clustering and CD44 Trafficking in Endothelial Cells (2014) (0)
Pathological Angiogenesis by Altering Lipid Raft Clustering and CD 44 Trafficking in Endothelial Cells (2014) (0)
Dissection of the h-2d region with monoclonal antibodies and cytotoxic t cells. Abstr. (1979) (0)
Design of inhibitors for the transporter associated with antigen processing (TAP) using peptidomimetics (1997) (0)
The role of HLA-DM for loading and selection of the peptide repertoire of MHC class-II molecules (1997) (0)
H-2 genes and function. (1989) (0)
NK Susceptibility of a Murine Class I Negative Tumor Variant Is Reversed after Reconstitution of MHC Class I Expression by Gene Transfection (1990) (0)
Antigen processing and recognition. (2006) (0)
Distinct recognition sites on histocompatibility antigens for antibodies and cytotoxic T lymphocytes. (1983) (0)
PROCESSING OF AN ENDOGENOUS PROTEIN CAN GENERATE MHC CLASS THOSE DERIVED FROM EXOGENOUS ANTIGEN 11-RESTRICTED T CELL DETERMINANTS DISTINCT FROM (1991) (0)
[Monoclonal antibodies in tumor diagnosis and tumor therapy]. (1986) (0)
SS1-4 Foxp3+ Tregs promote Th17 development in vivo by regulating IL-2 (2010) (0)
GENETIC CONTROL OF THE IMMUNE RESPONSE (1973) (0)
DifferentiationMemory CD8+ T Cell IFN-{gamma} Receptor Signaling (2010) (0)
This information is current as T Cell Differentiation + CD 8 Receptor Signaling Regulates Memory γ IFN - (2010) (0)
[Differential expression of major histocompatibility antigens in the normal gastrointestinal tract, in chronic inflammatory intestinal diseases and neoplasms]. (1989) (0)
Imaging of immune system (WS-052) Chairpersons: Takaharu Okada, Tri Phan (2010) (0)
transplantation regulatory T cells after experimental allogeneic bone marrow + FoxP3 + Identification and expansion of highly suppressive CD8 (2013) (0)
Target Recognition by Natural Killer Cells-Identification and Characterization of Inhibiting and Activating Factors (2007) (0)
O488 - The function of HLA-DM for peptide loading onto MHC class II molecules (1996) (0)
Tolerance induction in mature peripheral T cells (1994) (0)
Foxp3.LuciDTR Mice Regulatory T Cells in + Expansion of Foxp3 Dendritic Cells Support Homeostatic (2010) (0)
Homeostasis T Cell + Regulation of Antigen-Specific CD 8-Dependent γ Contribute to the IFN-Cutting Edge : Innate Immune Cells (2005) (0)
Ia antigens contain two distinct forms of beta chain. (1981) (0)
Mechanisms of Peripheral Tolerance (1993) (0)
TumorsAnti-DR5 Antibody Therapy in Established Contribute to the Tumoricidal Activity of Dendritic Cells and B Cells + CD11c (2010) (0)
Association in the expression of Ki-ras oncogene and MHC class I antigens in fibrosarcoma tumour cell variants exhibiting different metastatic capabilities (1987) (0)
active vessel remodeling during neovascularization Regulator of G-protein signaling-5 induction in pericytes coincides with (2010) (0)
Control of tumor immunity by the microenvironment: Overcoming the endothelial barrier (2008) (0)
Correction for Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy, by Babak H. Hosseini, Ilia Louban (2010) (0)

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