Guro Valen
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Norwegian physician
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Philosophy
Why Is Guro Valen Influential?
(Suggest an Edit or Addition)According to Wikipedia, Guro Valen was a Norwegian professor of medicine. She was a daughter of political scientist Henry Valen. She worked at the University of Tromsø, Karolinska Institutet and the University of Oslo, and was a fellow of the Norwegian Academy of Science and Letters. She died from cancer in September 2014.
Guro Valen's Published Works
Published Works
- Nuclear factor kappa-B and the heart. (2001) (462)
- The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. (2013) (366)
- Ischemic postconditioning: brief ischemia during reperfusion converts persistent ventricular fibrillation into regular rhythm. (2004) (127)
- Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery. (1998) (125)
- ADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques. (2008) (121)
- Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase. (2004) (96)
- Signal transduction through nuclear factor kappa B in ischemia-reperfusion and heart failure (2003) (94)
- Effects of sex, gonadectomy, and oestrogen substitution on ischaemic preconditioning and ischaemia-reperfusion injury in mice. (2003) (91)
- Increased circulating mitochondrial DNA after myocardial infarction. (2012) (86)
- Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1. (2000) (82)
- Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury. (2011) (81)
- Pretreating rats with hyperoxia attenuates ischemia-reperfusion injury of the heart. (2001) (80)
- Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque (2005) (79)
- Hyperoxia elicits myocardial protection through a nuclear factor kappaB-dependent mechanism in the rat heart. (2003) (79)
- Pathophysiology and mediators of ischemia-reperfusion injury with special reference to cardiac surgery. A review. (1993) (78)
- Induction of inflammatory mediators during reperfusion of the human heart. (2001) (77)
- Glucocorticoid pretreatment protects cardiac function and induces cardiac heat shock protein 72. (2000) (71)
- Sex differences in mouse heart rate and body temperature and in their regulation by adenosine A1 receptors (2007) (69)
- Expression of matrix metalloproteinase 9 and its regulators in the unstable coronary atherosclerotic plaque. (2005) (67)
- Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes (2016) (64)
- Adenosine A receptors are necessary for protection of the murine heart by remote, delayed adaptation to ischaemia. (2004) (61)
- Spontaneous Ischemic Events in the Brain and Heart Adapt the Hearts of Severely Atherosclerotic Mice to Ischemia (2002) (56)
- Fibrinolysis during cardiac surgery. Release of tissue plasminogen activator in arterial and coronary sinus blood. (1994) (55)
- Retinoic Acid Signalling Is Activated in the Postischemic Heart and May Influence Remodelling (2012) (55)
- Preconditioning and cardiac surgery. (2003) (54)
- Cardioprotection by breathing hyperoxic gas-relation to oxygen concentration and exposure time in rats and mice. (2002) (52)
- Remote Transplantation of Mesenchymal Stem Cells Protects the Heart Against Ischemia‐Reperfusion Injury (2014) (52)
- The basic biology of apoptosis and its implications for cardiac function and viability. (2003) (52)
- Preconditioning protects the severely atherosclerotic mouse heart. (2001) (52)
- Activation of Liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia–reperfusion injury (2012) (52)
- Vein graft harvesting induces inflammation and impairs vessel reactivity. (2006) (49)
- Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice. (2009) (46)
- Nitric oxide mediates protective effect of endothelin receptor antagonism during myocardial ischemia and reperfusion. (2004) (45)
- Pretreatment with hyperoxia reduces in vivo infarct size and cell death by apoptosis with an early and delayed phase of protection. (2011) (45)
- Pre– and postconditioning during cardiac surgery (2005) (44)
- Caught in the act: in vivo molecular imaging of the transcription factor NF-kappaB after myocardial infarction. (2006) (44)
- Innate immunity and myocardial adaptation to ischemia (2008) (42)
- Preconditioning with hydrogen peroxide (H2O2) or ischemia in H2O2-induced cardiac dysfunction. (1998) (42)
- Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia (2005) (39)
- Myocardial protection evoked by hyperoxic exposure involves signaling through nitric oxide and mitogen activated protein kinases (2006) (39)
- Heme oxygenase-1: an emerging therapeutic target to curb cardiac pathology (2014) (38)
- Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia. (2013) (38)
- Postconditioning in rats and mice (2006) (37)
- Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level. (2005) (35)
- Hydrogen peroxide induces endothelial cell atypia and cytoskeleton depolymerization. (1999) (35)
- Cellular signalling mechanisms in adaptation to ischemia-induced myocardial damage (2003) (33)
- Innate immunity and remodelling (2010) (33)
- Pretreatment with methylprednisolone protects the isolated rat heart against ischaemic and oxidative damage (2000) (33)
- Toxic oxygen metabolites and leukocytes in reperfusion injury. A review. (1993) (33)
- Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart. (2014) (32)
- Cardiac aquaporins (2013) (32)
- Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart. (2015) (32)
- Aquaporin-4 in the heart: expression, regulation and functional role in ischemia (2012) (31)
- Toxic oxygen metabolites and ischemia-reperfusion increase histamine synthesis and release in the isolated rat heart. (1993) (29)
- Preconditioning improves cardiac function after global ischemia, but not after cold cardioplegia. (1996) (27)
- Preconditioning effects of steroids and hyperoxia on cardiac ischemia-reperfusion injury and vascular reactivity. (2008) (27)
- Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo. (2011) (27)
- Cecal Ligation and Puncture Sepsis Is Associated with Attenuated Expression of Adenylyl Cyclase 9 and Increased Mir142-3p (2011) (26)
- Exposure of rats to hyperoxia enhances relaxation of isolated aortic rings and reduces infarct size of isolated hearts. (2002) (23)
- Effects of cardiac surgery on some clinically used inflammation markers and procalcitonin. (2000) (22)
- The cellular prion protein counteracts cardiac oxidative stress. (2014) (22)
- Gene expression of inflammatory mediators in different chambers of the human heart. (2000) (22)
- Does hypothermia or hyperkalemia influence the preconditioning response? (1999) (21)
- Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart. (2008) (21)
- Expression of retinoic acid target genes in coronary artery disease. (2014) (21)
- Release of von Willebrand factor by cardiopulmonary bypass, but not by cardioplegia in open heart surgery. (1994) (21)
- Effects of spontaneous or induced brain ischemia on vessel reactivity: the role of inducible nitric oxide synthase. (2002) (21)
- Hydrogen peroxide induces mRNA for tumour necrosis factor alpha in human endothelial cells. (1999) (20)
- Cyclic fluctuations in the cardiac performance of the isolated Langendorff-perfused mouse heart: pyruvate abolishes the fluctuations and has an anti-ischaemic effect. (2002) (20)
- Extracardiac approaches to protecting the heart. (2009) (19)
- Transient hyperosmolality modulates expression of cardiac aquaporins. (2012) (18)
- Increased expression of monocarboxylate transporter 1 after acute ischemia of isolated, perfused mouse hearts. (2009) (18)
- Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles (2018) (18)
- Release of tissue plasminogen activator during reperfusion after different times of ischaemia in isolated, perfused rat hearts. (1996) (18)
- Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs. (2004) (18)
- Perfusing isolated rat hearts with hydrogen peroxide: an experimental model of cardiac dysfunction caused by reactive oxygen species. (1996) (17)
- In vivo Remote Delivery of DNA Encoding for Hypoxia‐inducible Factor 1 Alpha Reduces Myocardial Infarct Size (2009) (15)
- Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation (2019) (15)
- The role of nitric oxide in ischaemia/reperfusion injury of isolated hearts from severely atherosclerotic mice. (2001) (15)
- The p66ShcA adaptor protein regulates healing after myocardial infarction (2015) (15)
- Gene Deletion of NF-κB p105 Enhances Neointima Formation in a Mouse Model of Carotid Artery Injury (2006) (14)
- Lipid peroxidation in open-heart surgery (1994) (14)
- Effects of a novel low-molecular weight antioxidant on cardiac injury induced by hydrogen peroxide. (1996) (14)
- Mechanical stress alters the expression of calcification-related genes in vascular interstitial and endothelial cells. (2019) (13)
- Oxidative stress and release of tissue plasminogen activator in isolated rat hearts. (1997) (13)
- Deficiency of Nitric Oxide Synthase 2 Results in Increased Neointima Formation in a Mouse Model of Vascular Injury (2003) (13)
- Inhibition of lipoxygenase and cyclooxygenase augments cardiac injury by H2O2. (1993) (13)
- Cloning and Functional Studies of a Splice Variant of CYP26B1 Expressed in Vascular Cells (2012) (12)
- Mechanical conversion of post-ischaemic ventricular fibrillation: effects on function and myocyte injury in isolated rat hearts. (1999) (12)
- Higher TNFα responses in young males compared to females are associated with attenuation of monocyte adenylyl cyclase expression. (2015) (12)
- Preconditioning the globally ischaemic, isolated rat heart: the impact of the preconditioning model on post-ischaemic systolic and diastolic function. (1997) (12)
- Can reactive oxygen species precondition the isolated rat heart against arrhythmias and stunning? (1997) (11)
- Histamine release and its effects in ischaemia-reperfusion injury of the isolated rat heart. (1994) (11)
- Evaluation of gene and cell-based therapies for cardiac regeneration. (2013) (11)
- Reactive oxygen intermediates and ischemia-reperfusion injury release tissue plasminogen activator from isolated rat hearts. (1993) (11)
- Adenosine increases LPS‐induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors (2014) (10)
- Interleukin-17 (IL-17) Expression Is Reduced during Acute Myocardial Infarction: Role on Chemokine Receptor Expression in Monocytes and Their in Vitro Chemotaxis towards Chemokines (2012) (10)
- Protecting the heart through delivering DNA encoding for heme oxygenase-1 into skeletal muscle. (2012) (10)
- A novel glutamate transporter blocker, LL-TBOA, attenuates ischaemic injury in the isolated, perfused rat heart despite low transporter levels. (2014) (10)
- Endothelin release at reperfusion of the porcine ischaemic heart in relation to noradrenaline and neuropeptide Y. (1994) (10)
- Effects of a novel, low-molecular weight inhibitor of lipid peroxidation on ischemia-reperfusion injury in isolated rat hearts and in cultured cardiomyocytes. (1998) (10)
- Post-ischaemic dysfunction does not correlate with release of cardiac troponin T in isolated rat hearts. (1999) (8)
- Connective Tissue Growth Factor/CCN2 Attenuates β-Adrenergic Receptor Responsiveness and Cardiotoxicity by Induction of G Protein–Coupled Receptor Kinase-5 in Cardiomyocytes (2013) (8)
- Preconditioning does not attenuate cardiac dysfunction after global ischaemia in the guinea-pig. (1998) (8)
- Activity of histamine metabolizing and catabolizing enzymes during reperfusion of isolated, globally ischemic rat hearts (1996) (8)
- Release of markers of myocardial and endothelial injury following cold cardioplegic arrest in pigs. (1997) (8)
- Open heart surgery increases the levels of histamine in arterial and coronary sinus blood (1994) (8)
- Indigenous Agency in the Amazon: The Mojos in Liberal and Rubber-Boom Bolivia, 1842–1932 (2013) (7)
- Blood of the Earth: Resource Nationalism, Revolution, and Empire in Bolivia (2019) (7)
- Release of creatine kinase, troponin-T, and tissue plasminogen activator in arterial and coronary venous blood during coronary artery bypass surgery. (1997) (7)
- The role of neuronal nitric oxide synthase in ischaemia-reperfusion injury of the isolated mouse heart. (2001) (7)
- Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans (2017) (6)
- Preoperative unstable angina causes venous adaptation to surgical graft injury (2007) (6)
- Systemic release of thrombomodulin, but not from the cardioplegic, reperfused heart during open heart surgery. (1996) (6)
- ISOFLURANE AND OTHER COMMONLY USED ANAESTHETICS DO NOT PROTECT THE ISOLATED BUFFER PERFUSED MOUSE HEART FROM ISCHEMIA‐REPERFUSION INJURY (2006) (6)
- Review: Indigenous Cultural Centers and Museums: An Illustrated International Survey by Anoma Pieris (2017) (5)
- Intraperitoneal injection induces a delayed preconditioning-like effect in mice (2005) (5)
- A role for NLRP3 inflammasome in acute myocardial ischaemia-reperfusion injury? Reply. (2013) (5)
- The effects of exogenous histamine in isolated rat hearts (1995) (5)
- The effect of exogenous adenosine on functional injury caused by hydrogen peroxide in the isolated rat heart. (1996) (4)
- Release of histamine from isolated rat hearts during reperfusion is not dependent on length of ischemic insult, or contents of histamine in cardiac tissue (1993) (4)
- Poster session 2 (2004) (4)
- Cardiac troponin T content in heart and skeletal muscle and in blood samples from ApoE/LDL receptor double knockout mice. (2004) (4)
- Could treatment with scavengers of oxygen free radicals minimize complications in cardiac surgery? (1991) (4)
- Importance of preanalytical handling of samples for measurement of cardiac troponin T in coronary effluent from isolated rat hearts (2002) (3)
- Small skin burn injury reduces cardiac tolerance to ischemia via a tumor necrosis factor alpha-dependent pathway. (2007) (3)
- Lazaroid U-83836E improves tolerance to hemorrhagic shock and limb ischemia and reperfusion in rats and increases cardiac heat shock protein 72. (2006) (3)
- Adaptation to Ischemia by in vivo Exposure to Hyperoxia—Signalling through Mitogen Activated Protein Kinases and Nuclear Factor Kappa B (2003) (2)
- Poster Session 2 (2009) (2)
- A dose–response study of glutamate supplementation in isolated, perfused rat hearts undergoing ischaemia and cold cardioplegia (2018) (2)
- Hyperoxia protects the isolated rat heart against ischaemia-reperfusion injury through a NFκB-dependent mechanism (2001) (2)
- A model of neointima formation in the atherosclerotic carotid artery of mice. (2003) (2)
- The search for markers of endothelial injury during open heart surgery. (1996) (2)
- Ischaemia-reperfusion and toxic oxygen metabolites do not induce release of immunoreactive atrial natriuretic factor from isolated rat hearts. (1993) (2)
- Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9 (2008) (1)
- P647Bone morphogenetic protein-2 is induced in the heart after ischemic injury (2014) (1)
- Remote, delayed preconditioning by I.P. injections — possible signalling through map kinases and NFκB (2002) (1)
- Gene Therapy of the Heart through Targeting Non-Cardiac Cells (2011) (1)
- 620 The role of tumor necrosis factor alpha in preconditioning by hyperoxia (2003) (1)
- Cardiac release of histamine after ventricular fibrillation and defibrillation during insertion of implantable cardioverter defibrillators (ICD) (1995) (1)
- P668Extracellular mitochondrial DNA induces cell death in cardiomyocytes (2014) (1)
- Outlawed: Between Security and Rights in a Bolivian City. By Daniel M. Goldstein. Durham: Duke UP, 2012, p. 327, $24.95. (2013) (1)
- Surgical handling, but not unstable angina, induces remodelling (2002) (0)
- Review Extracardiac approaches to protecting the heart (2009) (0)
- Work in progress report - Experimental A model of neointima formation in the atherosclerotic carotid artery of mice q (2003) (0)
- The effect of a low molecular weight inhibitor of lipid peroxidation on ultrastructural alterations to ischemia-reperfusion in the isolated rat heart. (2001) (0)
- Abstract 11803: Extracellular Mitochondrial DNA is a Putative Toll-Like Receptor 9 Agonist on Cardiac Fibroblasts During Myocardial Infarction (2011) (0)
- The effect of ischemia-reperfusion and toxic oxygen metabolites (TOM) on secretion of atrial natriuretic factor (ANF) from isolated rat hearts (1990) (0)
- Novel cardioprotective role of connective tissue growth factor (CTGF) in ischemia/reperfusion (2007) (0)
- Endothelial release of tissue plasminogen activator (t-PA) in the coronary circulation during ischemia - reperfusion (I/R) (1995) (0)
- A possible role for inducible nitric oxide synthase in hyperoxia-induced myocardial protection (2002) (0)
- Mitogen activated protein kinase (MAPK) signalling in different mice models of preconditioning (2002) (0)
- P138p66ShcA adaptor protein facilitates heart rupture via activation of MMP-2 in an in vivo model of myocardial infarction in mice. (2014) (0)
- Review: Bridget M. Chesterton (ed, 2016): The Chaco War, 1932-1935 (2017) (0)
- Remote delivery of DNA encoding for hypoxia-inducible factor 1 alpha protects against myocardial remodeling in vivo (2008) (0)
- A possible role for heme oxygenase 1 in myocardial protection afforded by hypoxia inducible factor 1 alpha (2008) (0)
- Abstract 2961: CCN2/CTGF - Connective Tissue Growth Factor - Reduces {beta}-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5 (2009) (0)
- GW24-e1418 Protective effect of bone morphogenetic protein 4(BMP4) on oxidative stress induced cardiomyocyte death (2013) (0)
- Sunday, 18 July 2010 (2010) (0)
- Inhibition of NFκB activation attenuates inflammation, but not neointima formation in a mouse model of carotid artery injury (2002) (0)
- 2P-0605 Unstable angina before open heart surgery reduces the inflammatory response to surgical handling of vein grafts (2003) (0)
- Review: Chesterton, Bridget M, ed (2016) The Chaco War 1932-1935. London: Bloomsburry (2017) (0)
- Chesterton, Bridget M (ed.) 2016 The Chaco War, 1932–1935. London: Bloomsbury. (2017) (0)
- Consequences of eliminating adenosine A1 receptors in mice (2003) (0)
- The role of nitric oxide in ischemia/reperfusion injury of the atherosclerotic mouse heart (2000) (0)
- The Seven Trees and Ramapough Ethnicity (2014) (0)
- Imperialism and the Origins of Mexican Culture by Colin M. MacLachlan (review) (2016) (0)
- Spontaneous ischemic events in atherosclerotic mice precondition their hearts (2000) (0)
- The Guaraní and Their Missions: A Socioeconomic History by Julia J. S. Sarreal (review) (2016) (0)
- A1 receptors mediate delayed remote preconditioning, possible involvement of mapk (2002) (0)
- Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein. (2022) (0)
- Gene delivery of hypoxia-inducible factor 1 alpha into skeletal muscle reduces myocardial infarct size 8 weeks later; evaluation of protection (2006) (0)
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What Schools Are Affiliated With Guro Valen?
Guro Valen is affiliated with the following schools: