Gustavo Turecki
#62,861
Most Influential Person Now
Canadian psychiatrist and academic
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Biology
Gustavo Turecki's Degrees
- PhD Psychiatry McGill University
Why Is Gustavo Turecki Influential?
(Suggest an Edit or Addition)According to Wikipedia, Gustavo Turecki is a Canadian psychiatrist, suicidologist, neuroscientist who is a professor at McGill University in Montreal, Quebec, Canada. He holds a Tier 1 Canada Research Chair Tier in Major Depressive Disorder and Suicide. He is the sitting Chair of the Department of Psychiatry at McGill University, the Scientific Director of the Douglas Research Centre, and the Psychiatrist-in-Chief of the Centre intégré universitaire de santé et de services sociaux de l’Ouest-de-l’Île-de-Montréal . He works at the Douglas Mental Health University Institute, where he heads both the McGill Group for Suicide Studies and the Depressive Disorders Program, and is the co-director of the Douglas Bell-Canada Brain Bank.
Gustavo Turecki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse (2009) (3151)
- Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters (2010) (1601)
- Analysis of shared heritability in common disorders of the brain (2016) (1385)
- Suicide and suicidal behaviour (2016) (1127)
- Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
- Suicide risk and prevention during the COVID-19 pandemic (2020) (928)
- Psychiatric diagnoses in 3275 suicides: a meta-analysis (2004) (769)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide (2003) (717)
- Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions (2007) (657)
- Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. (2003) (592)
- Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review (2016) (528)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Personality traits as correlates of suicidal ideation, suicide attempts, and suicide completions: a systematic review (2006) (513)
- Risk factors for suicide completion in major depression: a case-control study of impulsive and aggressive behaviors in men. (2005) (507)
- Social stress induces neurovascular pathology promoting depression (2017) (493)
- Genome-wide epigenetic regulation by early-life trauma. (2012) (442)
- Sex-specific transcriptional signatures in human depression (2017) (427)
- A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior (2003) (416)
- Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides (2014) (351)
- Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression (2009) (348)
- Suicide and suicide risk (2019) (342)
- Definition, Assessment, and Staging of Treatment—Resistant Refractory Major Depression: A Review of Current Concepts and Methods (2007) (341)
- Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report (2013) (340)
- Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain (2008) (333)
- Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and Humans (2013) (318)
- Differential Glucocorticoid Receptor Exon 1B, 1C, and 1H Expression and Methylation in Suicide Completers with a History of Childhood Abuse (2012) (313)
- Genome-wide association study reveals two new risk loci for bipolar disorder (2014) (311)
- Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus (2012) (291)
- A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders (2003) (286)
- The neurodevelopmental origins of suicidal behavior (2012) (280)
- Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide. (1999) (275)
- MicroRNA Expression Is Down-Regulated and Reorganized in Prefrontal Cortex of Depressed Suicide Subjects (2012) (273)
- Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress (2015) (270)
- PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome (2008) (269)
- Identification of a major susceptibility locus for restless legs syndrome on chromosome 12q. (2001) (268)
- Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study (2016) (258)
- International Society for Bipolar Disorders Task Force on Suicide: meta‐analyses and meta‐regression of correlates of suicide attempts and suicide deaths in bipolar disorder (2015) (256)
- Dissecting the suicide phenotype: the role of impulsive-aggressive behaviours. (2005) (256)
- Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci (2015) (252)
- Impulsive-aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide (2007) (248)
- Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression (2009) (245)
- miR-1202: A Primate Specific and Brain Enriched miRNA Involved in Major Depression and Antidepressant Treatment (2014) (243)
- Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology (2021) (240)
- Morphometric characterization of microglial phenotypes in human cerebral cortex (2014) (231)
- A functional myeloperoxidase polymorphic variant is associated with coronary artery disease in French-Canadians. (2001) (225)
- Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression (2013) (218)
- Astrocytic abnormalities and global DNA methylation patterns in depression and suicide (2014) (215)
- Suicide risk assessment and intervention in people with mental illness (2015) (213)
- The molecular bases of the suicidal brain (2014) (213)
- Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completers. (2009) (212)
- The emerging role of exosomes in mental disorders (2019) (208)
- What is the meaning of treatment resistant/refractory major depression (TRD)? A systematic review of current randomized trials (2007) (202)
- Peripheral SLC6A4 DNA Methylation Is Associated with In Vivo Measures of Human Brain Serotonin Synthesis and Childhood Physical Aggression (2012) (200)
- Predicting suicide attempts in young adults with histories of childhood abuse (2008) (198)
- DNA methylation and childhood maltreatment: From animal models to human studies (2014) (197)
- Characterization of impulsivity in suicide completers: clinical, behavioral and psychosocial dimensions. (2006) (190)
- Is violent method of suicide a behavioral marker of lifetime aggression? (2005) (183)
- The Impact of Phenotypic and Genetic Heterogeneity on Results of Genome Wide Association Studies of Complex Diseases (2013) (181)
- Patterns of gene expression in the limbic system of suicides with and without major depression (2007) (180)
- Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons (2020) (179)
- Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides (2011) (171)
- Genome-wide methylation changes in the brains of suicide completers. (2013) (169)
- Current psychiatric morbidity, aggression/impulsivity, and personality dimensions in child and adolescent suicide: a case-control study. (2008) (167)
- Familial aggregation of suicidal behavior: a family study of male suicide completers from the general population. (2005) (167)
- Medial prefrontal cortex activity during memory encoding of pictures and its relation to symptomatic improvement after citalopram treatment in patients with major depression. (2010) (165)
- Implication of SSAT by gene expression and genetic variation in suicide and major depression. (2006) (162)
- Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell (2013) (159)
- Mapping susceptibility genes for bipolar disorder: a pharmacogenetic approach based on excellent response to lithium (2001) (158)
- BECon: a tool for interpreting DNA methylation findings from blood in the context of brain (2017) (158)
- Risk factors for suicide completion in borderline personality disorder: a case-control study of cluster B comorbidity and impulsive aggression. (2007) (155)
- An examination of DSM-IV depressive symptoms and risk for suicide completion in major depressive disorder: a psychological autopsy study. (2007) (155)
- Familial aggregation of suicide explained by cluster B traits: a three-group family study of suicide controlling for major depressive disorder. (2009) (153)
- Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. (2016) (153)
- Role of Tet1 and 5-hydroxymethylcytosine in cocaine action (2015) (147)
- Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder (2014) (145)
- Diagnosing Zygosity in Infant Twins: Physical Similarity, Genotyping, and Chorionicity (2003) (145)
- GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. (2019) (144)
- The efficacy of omega-3 supplementation for major depression: a randomized controlled trial. (2011) (143)
- Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia (2014) (140)
- Through the looking glass: examining neuroanatomical evidence for cellular alterations in major depression. (2009) (140)
- Dysregulation of the sympathetic nervous system, hypothalamic-pituitary-adrenal axis and executive function in individuals at risk for suicide. (2010) (138)
- Epigenetic regulation of BDNF expression according to antidepressant response (2013) (137)
- Suicidal behavior: is there a genetic predisposition? (2001) (136)
- Are coping strategies, social support, and hope associated with psychological distress among Hurricane Katrina survivors? (2009) (136)
- Intravenous arketamine for treatment-resistant depression: open-label pilot study (2020) (135)
- The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment (2010) (135)
- The relationship of impulsive aggressiveness to suicidality and other depression-linked behaviors (2007) (134)
- Molecular adaptations of the blood–brain barrier promote stress resilience vs. depression (2020) (132)
- T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability. (1999) (132)
- MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes (2017) (131)
- Concordant and discordant DNA methylation signatures of aging in human blood and brain (2015) (129)
- Suicide neurobiology (2009) (129)
- Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia (2017) (129)
- Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction (2011) (128)
- Evidence for a role of phospholipase C-γ1 in the pathogenesis of bipolar disorder (1998) (126)
- Association of a History of Child Abuse With Impaired Myelination in the Anterior Cingulate Cortex: Convergent Epigenetic, Transcriptional, and Morphological Evidence. (2017) (126)
- Implication of the polyamine system in mental disorders. (2008) (125)
- Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder (2015) (125)
- Suicidality and risk of suicide--definition, drug safety concerns, and a necessary target for drug development: a consensus statement. (2010) (124)
- Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study (2017) (122)
- The genetics of suicide: a critical review of molecular studies. (2008) (121)
- Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity. (2005) (120)
- Associations Between Peer Victimization and Suicidal Ideation and Suicide Attempt During Adolescence: Results From a Prospective Population-Based Birth Cohort. (2016) (119)
- Early life adversity, genomic plasticity, and psychopathology. (2014) (118)
- Dysfunction of Astrocyte Connexins 30 and 43 in Dorsal Lateral Prefrontal Cortex of Suicide Completers (2011) (112)
- Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: A case–control study (2006) (111)
- A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13 (2006) (105)
- Discovering biomarkers for antidepressant response: protocol from the Canadian biomarker integration network in depression (CAN-BIND) and clinical characteristics of the first patient cohort (2016) (103)
- Methylation of the glucocorticoid receptor gene promoter in bulimic women: associations with borderline personality disorder, suicidality, and exposure to childhood abuse. (2013) (102)
- Patterns of co-morbidity in male suicide completers (2003) (101)
- Neuropathology of suicide: recent findings and future directions (2017) (101)
- Deficit of cognitive inhibition in depressed elderly: a neurocognitive marker of suicidal risk. (2012) (101)
- Current trends in the assessment and somatic treatment of resistant/refractory major depression: An overview (2008) (100)
- The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls (2018) (99)
- Natural history of suicidal behaviors in a population-based sample of young adults (2007) (99)
- Differences and similarities in the serotonergic diathesis for suicide attempts and mood disorders: a 22-year longitudinal gene–environment study (2010) (99)
- Effect of Tryptophan Hydroxylase-2 Gene Variants on Suicide Risk in Major Depression (2007) (99)
- Stalled developmental programs at the root of pediatric brain tumors (2019) (96)
- Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking (2020) (96)
- Evidence for a genetic association between monoamine oxidase A and restless legs syndrome (2002) (95)
- MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels. (2009) (94)
- Histone methylation and decreased expression of TrkB.T1 in orbital frontal cortex of suicide completers (2009) (93)
- Glial fibrillary acidic protein is differentially expressed across cortical and subcortical regions in healthy brains and downregulated in the thalamus and caudate nucleus of depressed suicides (2016) (92)
- Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study (2018) (92)
- Association between the methylenetetrahydrofolate reductase 677C→T missense mutation and schizophrenia (2000) (92)
- Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampi (2015) (91)
- DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218 (2017) (90)
- Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects (2014) (90)
- CAG repeat length in RAI1 is associated with age at onset variability in spinocerebellar ataxia type 2 (SCA2). (2000) (89)
- Suicide and no axis I psychopathology (2004) (88)
- Alcohol and Cigarette Use and Misuse Among Hurricane Katrina Survivors: Psychosocial Risk and Protective Factors (2009) (88)
- Association of Childhood Irritability and Depressive/Anxious Mood Profiles With Adolescent Suicidal Ideation and Attempts (2018) (88)
- Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers. (2014) (88)
- Life trajectories and burden of adversity: mapping the developmental profiles of suicide mortality (2007) (87)
- Dopaminergic neurotransmission and restless legs syndrome: A genetic association analysis (2001) (87)
- Lithium response and genetic variation in the CREB family of genes (2008) (87)
- Monoamine oxidase a gene promoter methylation and transcriptional downregulation in an offender population with antisocial personality disorder (2015) (87)
- VGF function in depression and antidepressant efficacy (2017) (87)
- Youth and young adult suicide: a study of life trajectory. (2011) (85)
- Meta-analysis of the association between tryptophan hydroxylase and suicidal behavior. (2002) (84)
- Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response (2018) (83)
- Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions (2016) (83)
- Personality traits as correlates of suicide attempts and suicidal ideation in young adults (2005) (83)
- Distribution of vesicular glutamate transporters in the human brain (2015) (83)
- A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder (2015) (83)
- Cognitive inhibition in depression and suicidal behavior: a neuroimaging study (2015) (82)
- Cholesterol content in brains of suicide completers. (2007) (81)
- The 14q restless legs syndrome locus in the French Canadian population (2004) (81)
- dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients (2013) (80)
- Elevated gene expression of glutamate receptors in noradrenergic neurons from the locus coeruleus in major depression. (2014) (79)
- Identifying correlates of suicide attempts in suicidal ideators: a population-based study (2007) (78)
- The effect of genetic variation of the serotonin 1B receptor gene on impulsive aggressive behavior and suicide (2007) (78)
- Gene expression deficits in pontine locus coeruleus astrocytes in men with major depressive disorder. (2013) (78)
- Identification of shared risk loci and pathways for bipolar disorder and schizophrenia (2017) (78)
- Restless legs syndrome‐associated MEIS1 risk variant influences iron homeostasis (2011) (77)
- G9a influences neuronal subtype specification in striatum (2014) (77)
- Family study of restless legs syndrome in Quebec, Canada: clinical characterization of 671 familial cases. (2010) (77)
- A genome‐wide association study of suicidal behavior (2015) (77)
- Increased tryptophan hydroxylase immunoreactivity in the dorsal raphe nucleus of alcohol‐dependent, depressed suicide subjects is restricted to the dorsal subnucleus (2006) (76)
- Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers (2012) (75)
- Efficacy and safety of adjunctive therapy using esketamine or racemic ketamine for adult treatment-resistant depression: A randomized, double-blind, non-inferiority study. (2019) (74)
- The Epigenetics of Suicide: Explaining the Biological Effects of Early Life Environmental Adversity (2010) (73)
- Suicidality and risk of suicide--definition, drug safety concerns, and a necessary target for drug development: a brief report. (2010) (73)
- Childhood trajectories of peer victimization and prediction of mental health outcomes in midadolescence: a longitudinal population-based study (2018) (71)
- ACF chromatin remodeling complex mediates stress–induced depressive–like behavior (2015) (70)
- TPH and suicidal behavior: a study in suicide completers (2001) (70)
- Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing (2015) (69)
- Gender and risk factors for suicide: evidence for heterogeneity in predisposing mechanisms in a psychological autopsy study. (2006) (69)
- Developmental model of suicide trajectories (2014) (69)
- Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions (2015) (69)
- Role of Complex Epigenetic Switching in Tumor Necrosis Factor-α Upregulation in the Prefrontal Cortex of Suicide Subjects. (2018) (68)
- H3K4 tri-methylation in synapsin genes leads to different expression patterns in bipolar disorder and major depression. (2013) (67)
- Sensitive periods in epigenetics: bringing us closer to complex behavioral phenotypes. (2012) (67)
- Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness (2017) (67)
- Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors (2020) (66)
- First-degree relatives of suicide completers may have impaired decision-making but functional cognitive control. (2015) (66)
- CANADIAN RESTLESS LEGS SYNDROME TWIN STUDY (2007) (65)
- Brain Serotonin Synthesis in Adult Males Characterized by Physical Aggression during Childhood: A 21-Year Longitudinal Study (2010) (64)
- Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities. (2012) (64)
- Childhood trajectories of anxiousness and disruptiveness as predictors of suicide attempts. (2008) (63)
- Characterization of QKI Gene Expression, Genetics, and Epigenetics in Suicide Victims with Major Depressive Disorder (2009) (63)
- Profiling brain expression of the spermidine/spermine N1‐acetyltransferase 1 (SAT1) gene in suicide (2009) (63)
- Transgenerational epigenetic inheritance: an open discussion. (2015) (62)
- Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence (2017) (62)
- Suicide Cases in New Brunswick from April 2002 to May 2003: The Importance of Better Recognizing Substance and Mood Disorder Comorbidity (2006) (61)
- Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder (2015) (61)
- Epigenetic regulation of spermidine/spermine N1-acetyltransferase (SAT1) in suicide. (2011) (60)
- Gene expression biomarkers of response to citalopram treatment in major depressive disorder (2011) (60)
- Repression of Astrocytic Connexins in Cortical and Subcortical Brain Regions and Prefrontal Enrichment of H3K9me3 in Depression and Suicide (2016) (60)
- Genome wide gene expression studies in mood disorders. (2006) (59)
- Epigenetic Regulation of the Kappa Opioid Receptor by Child Abuse (2017) (59)
- Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide (2017) (59)
- Plasticity of the epigenome during early-life stress. (2017) (58)
- Wolfram syndrome and suicide: Evidence for a role of WFS1 in suicidal and impulsive behavior (2003) (58)
- Mental health of the mothers of malnourished children. (1996) (58)
- A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline (2018) (57)
- Suicide and serotonin: Study of variation at seven serotonin receptor genes in suicide completers (2003) (57)
- Decreased global methylation in patients with bipolar disorder who respond to lithium. (2014) (57)
- Attentional bias toward suicide-relevant information in suicide attempters: A cross-sectional study and a meta-analysis. (2016) (57)
- MAOA: association and linkage studies with lithium responsive bipolar disorder. (1999) (57)
- SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer’s Disease (2012) (57)
- DRD3 and DAT1 genes in schizophrenia: an association study. (2000) (57)
- Systematic Services Audit of Consecutive Suicides in New Brunswick: The Case for Coordinating Specialist Mental Health and Addiction Services (2008) (56)
- Suicide among Inuit: Results from a Large, Epidemiologically Representative Follow-Back Study in Nunavut (2015) (56)
- Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex (2019) (56)
- Testing the Predictive Value of Peripheral Gene Expression for Nonremission Following Citalopram Treatment for Major Depression (2015) (56)
- DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-Locus Comparisons (2015) (56)
- Fatty acid composition in postmortem brains of people who completed suicide. (2007) (56)
- STin2 Variant and Family History of Suicide as Significant Predictors of Suicide Completion in Major Depression (2006) (55)
- Functional DNA methylation in a transcript specific 3′UTR region of TrkB associates with suicide (2014) (55)
- Anterior cingulate pyramidal neurons display altered dendritic branching in depressed suicides. (2010) (55)
- Altered expression of lipid metabolism and immune response genes in the frontal cortex of suicide completers. (2010) (55)
- Childhood trajectories of anxiousness and disruptiveness explain the association between early-life adversity and attempted suicide (2012) (55)
- Investigating responders to lithium prophylaxis as a strategy for mapping susceptibility genes for bipolar disorder (2005) (55)
- Cross-prevalence of migraine and bipolar disorder. (2010) (54)
- Implication of synapse-related genes in bipolar disorder by linkage and gene expression analyses. (2010) (54)
- Polyamines are implicated in the emergence of the embryo from obligate diapause. (2011) (53)
- What is specific to suicide in schizophrenia disorder? Demographic, clinical and behavioural dimensions (2008) (53)
- Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients (2016) (53)
- Subchronic Peripheral Neuregulin-1 Increases Ventral Hippocampal Neurogenesis and Induces Antidepressant-Like Effects (2011) (53)
- Autosomal‐dominant locus for restless legs syndrome in French‐Canadians on chromosome 16p12.1 (2009) (53)
- Perinatal depression and DNA methylation of oxytocin-related genes: a study of mothers and their children (2017) (52)
- Spectroscopy markers of suicidal risk and mental pain in depressed patients (2017) (52)
- Animal models to improve our understanding and treatment of suicidal behavior (2017) (52)
- Lithium responsive bipolar disorder, unilineality, and chromosome 18: A linkage study. (1999) (51)
- Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility (2018) (51)
- Recent and lifetime utilization of health care services by children and adolescent suicide victims: a case-control study. (2009) (51)
- Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E (2018) (51)
- Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers. (2010) (50)
- Complement component 3a receptor deficiency attenuates chronic stress-induced monocyte infiltration and depressive-like behavior (2018) (50)
- Evidence of Altered Polyamine Concentrations in Cerebral Cortex of Suicide Completers (2010) (49)
- Child abuse associates with an imbalance of oligodendrocyte-lineage cells in ventromedial prefrontal white matter (2018) (49)
- Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene (1996) (49)
- Symptomatic and Functional Outcomes and Early Prediction of Response to Escitalopram Monotherapy and Sequential Adjunctive Aripiprazole Therapy in Patients With Major Depressive Disorder: A CAN-BIND-1 Report. (2019) (49)
- Identification of Lithium-Regulated Genes in Cultured Lymphoblasts of Lithium Responsive Subjects with Bipolar Disorder (2004) (49)
- Personal and family history of suicidal behaviour is associated with lower peripheral cortisol in depressed outpatients. (2011) (49)
- Epigenetics and suicidal behavior research pathways. (2014) (49)
- Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons. (2019) (48)
- A psychological autopsy study of suicide among Inuit in Nunavut: methodological and ethical considerations, feasibility and acceptability (2013) (48)
- Dopamine Beta‐Hydroxylase (DBH) gene and schizophrenia phenotypic variability: A genetic association study (2003) (48)
- Quantifying RNA allelic ratios by microfluidics-based multiplex PCR and deep sequencing (2013) (48)
- Alpha 2A adrenergic receptor gene and suicide (2004) (48)
- The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study. (2018) (48)
- MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression (2015) (47)
- Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response (2017) (47)
- The effects of pH on DNA methylation state: In vitro and post-mortem brain studies (2008) (46)
- Association of Social Support During Adolescence With Depression, Anxiety, and Suicidal Ideation in Young Adults (2020) (46)
- Global gene expression profiling of the polyamine system in suicide completers. (2011) (46)
- High frequency repetitive transcranial magnetic stimulation as an augmenting strategy in severe treatment-resistant major depression: a prospective 4-week naturalistic trial. (2011) (46)
- Methylome-wide association findings for major depressive disorder overlap in blood and brain and replicate in independent brain samples (2018) (46)
- Association and linkage studies of candidate genes involved in GABAergic neurotransmission in lithium-responsive bipolar disorder. (2000) (46)
- No association between chromosome-18 markers and lithiumresponsive affective disorders (1996) (45)
- Histone arginine methylation in cocaine action in the nucleus accumbens (2016) (45)
- Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide. (2012) (45)
- Gene-body 5-hydroxymethylation is associated with gene expression changes in the prefrontal cortex of depressed individuals (2017) (45)
- Novel integrative genomic tool for interrogating lithium response in bipolar disorder (2015) (45)
- Pharmacogenomics of suicidal events. (2010) (45)
- Family history of suicidal behavior predicts impulsive-aggressive behavior levels in psychiatric outpatients. (2009) (45)
- Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer’s Disease patients (2012) (45)
- Disruption of GRIN2B Impairs Differentiation in Human Neurons (2018) (45)
- Epigenetic regulation of synaptic remodeling in stress disorders (2013) (44)
- Sexual Orientation and Gender Identity in Youth Suicide Victims: An Exploratory Study (2010) (44)
- Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior (2017) (44)
- Analysis of 14 CAG repeat-containing genes in schizophrenia. (1999) (44)
- Schizophrenia and chromosome 6p. (1997) (44)
- Pathways of Association Between Childhood Irritability and Adolescent Suicidality. (2019) (44)
- Risk factor modifications and depression incidence: a 4-year longitudinal Canadian cohort of the Montreal Catchment Area Study (2017) (43)
- Augmenting antidepressants with deep transcranial magnetic stimulation (DTMS) in treatment-resistant major depression (2014) (43)
- Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide. (2013) (43)
- Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide. (2013) (43)
- Effects of the MAOA gene and levels of exposure to violence on antisocial outcomes (2016) (43)
- Broad and narrow personality traits as markers of one-time and repeated suicide attempts: A population-based study (2008) (43)
- Obsessive-compulsive personality disorder and suicidal behavior: evidence for a positive association in a sample of depressed patients. (2009) (43)
- Childhood maltreatment and stress-related psychopathology: the epigenetic memory hypothesis. (2015) (43)
- Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. (2013) (43)
- Altered brain processing of decision-making in healthy first-degree biological relatives of suicide completers (2017) (42)
- Initial association of NR2E1 with bipolar disorder and identification of candidate mutations in bipolar disorder, schizophrenia, and aggression through resequencing (2008) (42)
- Tryptophan via serotonin/kynurenine pathways abnormalities in a large cohort of aggressive inmates: markers for aggression (2016) (42)
- BDNF protein levels are decreased in transformed lymphoblasts from lithium-responsive patients with bipolar disorder. (2008) (42)
- Course of major depressive disorder and suicide outcome: a psychological autopsy study. (2008) (42)
- Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide (2016) (42)
- Suicide and gambling: psychopathology and treatment-seeking. (2010) (41)
- Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2 (2017) (40)
- Cholesterol metabolism and suicidality in Smith-Lemli-Opitz syndrome carriers. (2004) (40)
- Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research (2018) (40)
- Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence. (2019) (39)
- Family-based exome-sequencing approach identifies rare susceptibility variants for lithium-responsive bipolar disorder. (2013) (39)
- Analysis of oxysterols and cholesterol in prefrontal cortex of suicides. (2013) (38)
- Lithium: a key to the genetics of bipolar disorder (2009) (38)
- Mental Health Problems and Risk of Suicidal Ideation and Attempts in Adolescents (2020) (38)
- Quais são os recentes achados clínicos sobre a associação entre depressão e suicídio? What are the recent clinical findings regarding the association between depression and suicide? (2009) (38)
- Association of Polyaminergic Loci With Anxiety, Mood Disorders, and Attempted Suicide (2010) (38)
- Co-Variation of Peripheral Levels of miR-1202 and Brain Activity and Connectivity During Antidepressant Treatment (2017) (38)
- Neurocognitive alterations in first degree relatives of suicide completers. (2013) (37)
- Seasonal differences in psychopathology of male suicide completers. (2004) (37)
- Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides (2018) (37)
- Comparative study of esketamine and racemic ketamine in treatment-resistant depression (2018) (37)
- Association of polygenic score for major depression with response to lithium in patients with bipolar disorder (2020) (37)
- Depression and Social Defeat Stress Are Associated with Inhibitory Synaptic Changes in the Nucleus Accumbens (2020) (36)
- Effects of Postmortem Interval on Biomolecule Integrity in the Brain (2015) (36)
- miR-323a regulates ERBB4 and is involved in depression (2020) (36)
- Characterizing 5-hydroxymethylcytosine in human prefrontal cortex at single base resolution (2015) (36)
- Tryptophan hydroxylase2 gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans (2012) (36)
- Psychiatric Risk Factors for Motor Vehicle Fatalities in Young Men (2005) (35)
- Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue (2022) (35)
- Association between irritability and suicide-related outcomes across the life-course. Systematic review of both community and clinical studies. (2018) (35)
- Potential Use of MicroRNA for Monitoring Therapeutic Response to Antidepressants (2017) (34)
- Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors. (2015) (34)
- Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia. (1999) (34)
- In-utero and perinatal influences on suicide risk: a systematic review and meta-analysis. (2019) (34)
- Panic disorder and suicidality: is comorbidity with depression the key? (2007) (34)
- Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors (2019) (34)
- Synapsin II Is Involved in the Molecular Pathway of Lithium Treatment in Bipolar Disorder (2012) (33)
- A quantitative GC-MS method for three major polyamines in postmortem brain cortex. (2009) (33)
- Implication of LRRC4C and DPP6 in neurodevelopmental disorders (2017) (33)
- Identification and Characterization of Spermidine/Spermine N1-Acetyltransferase Promoter Variants in Suicide Completers (2009) (33)
- Service Use and Unmet Needs in Youth Suicide: A Study of Trajectories (2014) (33)
- Suicide and the serotonin transporter gene (2001) (33)
- The epigenetic effects of antidepressant treatment on human prefrontal cortex BDNF expression. (2011) (33)
- Use of Machine Learning for Predicting Escitalopram Treatment Outcome From Electroencephalography Recordings in Adult Patients With Depression (2020) (33)
- Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility (2017) (33)
- A role for activity‐dependent epigenetics in the development and treatment of major depressive disorder (2018) (33)
- Gender-specific suicide risk factors: a case-control study of individuals with major depressive disorder. (2013) (32)
- A MBD-seq protocol for large-scale methylome-wide studies with (very) low amounts of DNA (2017) (32)
- VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine (2018) (32)
- Subtype (2020) (32)
- Cellular and Molecular Inflammatory Profile of the Choroid Plexus in Depression and Suicide (2015) (32)
- O suicídio e sua relação com o comportamento impulsivo-agressivo (1999) (32)
- A Slice of the Suicidal Brain: What Have Postmortem Molecular Studies Taught Us? (2016) (32)
- DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects (2017) (31)
- The Canadian Biomarker Integration Network in Depression (CAN-BIND): magnetic resonance imaging protocols (2019) (31)
- Antidepressive effects of targeting ELK-1 signal transduction (2018) (31)
- Levels of aggressiveness are higher among alcohol-related suicides: results from a psychological autopsy study. (2012) (31)
- Lack of association between bipolar disorder and tyrosine hydroxylase (1997) (31)
- [Which are the recent clinical findings regarding the association between depression and suicide?]. (2009) (31)
- Cybervictimization in adolescence and its association with subsequent suicidal ideation/attempt beyond face-to-face victimization: a longitudinal population-based study. (2020) (31)
- Neuroimaging-informed phenotypes of suicidal behavior: a family history of suicide and the use of a violent suicidal means (2018) (31)
- Interpersonal Circumplex Profiles Of Persistent Depression: Goals, Self-Efficacy, Problems, And Effects Of Group Therapy. (2017) (30)
- Mutational analysis of neurotensin in familial restless legs syndrome (2004) (30)
- Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine (2017) (30)
- Suicide and the polyamine system. (2013) (29)
- GPR56/ADGRG1 is associated with response to antidepressant treatment (2020) (29)
- Identification of three polymorphisms in the translated region of PLC-gamma1 and their investigation in lithium responsive bipolar disorder. (2001) (29)
- Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors (2018) (29)
- Association and linkage studies of CRH and PENK genes in bipolar disorder: a collaborative IGSLI study. (2000) (28)
- An Examination of DSM-IV Borderline Personality Disorder Symptoms and Risk for Death by Suicide: A Psychological Autopsy Study (2009) (28)
- PSEN1 and PSEN2 gene expression in Alzheimer's disease brain: a new approach. (2014) (28)
- Bipolar disorder following a left basal-ganglia stroke (1993) (28)
- Enrichment methods provide a feasible approach to comprehensive and adequately powered investigations of the brain methylome (2017) (28)
- Molecular genetic studies of DMT1 on 12q in French‐Canadian restless legs syndrome patients and families (2007) (28)
- Bridging Basic and Clinical Research in Early Life Adversity, DNA Methylation, and Major Depressive Disorder (2019) (27)
- The relationship between plasma serotonin and kynurenine pathway metabolite levels and the treatment response to escitalopram and desvenlafaxine (2020) (27)
- Linkage to the CCM2 Locus and Genetic Heterogeneity in Familial Cerebral Cavernous Malformation (2003) (27)
- Low gene expression of bone morphogenetic protein 7 in brainstem astrocytes in major depression. (2012) (27)
- Cell Type–Specific Methylome-wide Association Studies Implicate Neurotrophin and Innate Immune Signaling in Major Depressive Disorder (2019) (27)
- Type I bipolar disorder associated with a fragile site on chromosome 1. (1995) (27)
- Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides (2019) (27)
- A Genome-Wide Copy Number Variant Study of Suicidal Behavior (2015) (26)
- Predisposition to treatment response in major depressive episode: A peripheral blood gene coexpression network analysis. (2016) (26)
- Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers. (2009) (26)
- Transcriptomic and epigenomic biomarkers of antidepressant response. (2017) (26)
- Structural brain abnormalities in patients with type I bipolar disorder and suicidal behavior (2017) (26)
- Glucocorticoid regulates TrkB protein levels via c-Cbl dependent ubiquitination: A decrease in c-Cbl mRNA in the prefrontal cortex of suicide subjects (2014) (25)
- Neuron-derived extracellular vesicles enriched from plasma show altered size and miRNA cargo as a function of antidepressant drug response (2021) (25)
- Are neuroticism and extraversion associated with the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS)? An exploratory 4-week trial (2013) (25)
- A Deletion in Tropomyosin-Related Kinase B and the Development of Human Anxiety (2011) (24)
- Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder (2018) (24)
- The Epigenetics of Early Life Adversity: Current Limitations and Possible Solutions. (2018) (24)
- Comparison of Mental Health Symptoms prior to and during COVID-19: Evidence from a Living Systematic Review and Meta-analysis (2021) (24)
- Integrated genome-wide methylation and expression analyses reveal functional predictors of response to antidepressants (2019) (24)
- Clinical, behavioral, and neural measures of reward processing correlate with escitalopram response in depression: a Canadian Biomarker Integration Network in Depression (CAN-BIND-1) Report (2020) (24)
- A genetically informed study on the association of cannabis, alcohol, and tobacco smoking with suicide attempt (2020) (24)
- CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients. (2012) (24)
- Genome-wide DNA methylation meta-analysis in the brains of suicide completers (2020) (24)
- Broadening our horizons: Gene expression profiling to help better understand the neurobiology of suicide and depression (2012) (24)
- No association between the PREP gene and lithium responsive bipolar disorder (2007) (23)
- Effects of neuregulin-1 administration on neurogenesis in the adult mouse hippocampus, and characterization of immature neurons along the septotemporal axis (2016) (23)
- Epigenetic Effects of Childhood Adversity in the Brain and Suicide Risk (2012) (23)
- Pharmacogenomic predictors of citalopram treatment outcome in major depressive disorder (2014) (23)
- Polyglutamine-containing proteins in schizophrenia (1999) (23)
- Risks of suicide and poisoning among elderly patients prescribed selective serotonin reuptake inhibitors: a retrospective cohort study. (2008) (23)
- Neurocognitive Vulnerability: Suicidal and Homicidal Behaviours in Patients with Schizophrenia (2014) (23)
- Alterations in phosphorylated cAMP response element‐binding protein (pCREB) signaling: an endophenotype of lithium‐responsive bipolar disorder? (2013) (22)
- Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour. (2013) (22)
- Genome-wide association study identifies 30 loci associated with bipolar disorder (2019) (22)
- Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide (2017) (22)
- Investigating the role of hopelessness in the relationship between PTSD symptom change and suicidality. (2018) (22)
- Suicide and assisted dying in dementia: what we know and what we need to know. A narrative literature review (2017) (22)
- Trajectories of suicide attempts from early adolescence to emerging adulthood: prospective 11-year follow-up of a Canadian cohort (2020) (22)
- Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicides (2015) (22)
- A direct interaction between two Restless Legs Syndrome predisposing genes: MEIS1 and SKOR1 (2018) (21)
- DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression (2016) (21)
- Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and Humans (2013) (21)
- Suicide attempts in major depressed patients with personality disorder. (2014) (21)
- Age-dependent effect of the MAOA gene on childhood physical aggression (2013) (21)
- Confirmation of region-specific patterns of gene expression in the human brain (2007) (21)
- Increased doublecortin (DCX) expression and incidence of DCX-immunoreactive multipolar cells in the subventricular zone-olfactory bulb system of suicides (2015) (21)
- Analysis of CAG repeat expansions in restless legs syndrome. (2003) (20)
- A visual analog scale to measure psychological and physical pain: A preliminary validation of the PPP-VAS in two independent samples of depressed patients (2019) (20)
- Pharmacogenetics and bipolar disorder (2004) (20)
- Regulation of impulsive and aggressive behaviours by a novel lncRNA (2020) (20)
- Gene expression profiling of suicide completers (2010) (20)
- Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder (2016) (20)
- Neurobiology of Elderly Suicide (2016) (20)
- No association between chromosome-18 markers and lithium-responsive affective disorders. (1996) (20)
- Investigation of completed suicide and genes involved in cholesterol metabolism. (2004) (20)
- Differential Expression of FosB Proteins and Potential Target Genes in Select Brain Regions of Addiction and Depression Patients (2016) (20)
- Cannabis use, depression and suicidal ideation in adolescence: direction of associations in a population based cohort. (2020) (19)
- The Multidrug Resistance 1 Gene Abcb1 in Brain and Placenta: Comparative Analysis in Human and Guinea Pig (2014) (19)
- Identifying the Common Genetic Basis of Antidepressant Response (2021) (19)
- X chromosome and suicide (2011) (19)
- Association of the SAT1 in/del polymorphism with suicide completion (2009) (19)
- Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study (2018) (19)
- Response to treatment in bipolar disorder (2011) (18)
- Functional network alterations differently associated with suicidal ideas and acts in depressed patients: an indirect support to the transition model (2021) (18)
- Correlates of Attempted Suicide from the Emergency Room of 2 General Hospitals in Montreal, Canada (2016) (18)
- The Biobanque québécoise de la COVID-19 (BQC19)—A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories (2021) (18)
- Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients (2017) (18)
- Cholesterol and phospholipids in frontal cortex and synaptosomes of suicide completers: relationship with endosomal lipid trafficking genes. (2013) (18)
- Lack of association between bipolar disorder and tyrosine hydroxylase: a meta-analysis. (1996) (17)
- Epigenetic markers in inflammation-related genes associated with mood disorder: a cross-sectional and longitudinal study in high-risk offspring of bipolar parents (2019) (17)
- Serotonin transporter gene promoter methylation in peripheral cells in healthy adults: Neural correlates and tissue specificity (2017) (17)
- Connectomics-Based Functional Network Alterations in both Depressed Patients with Suicidal Behavior and Healthy Relatives of Suicide Victims (2019) (17)
- No evidence for GADL1 variation as a bipolar disorder susceptibility factor in a Caucasian lithium-responsive cohort. (2015) (17)
- Investigating epigenetic consequences of early-life adversity: some methodological considerations (2016) (17)
- Differential Treatment Benefit Prediction For Treatment Selection in Depression: A Deep Learning Analysis of STAR*D and CO-MED Data (2019) (17)
- Cognitive Behavioural Analysis System of Psychotherapy for Treatment-Resistant Depression: Adaptation to a Group Modality (2012) (17)
- Molecular characterization of suicide by microarray analysis (2005) (17)
- The network structure of core depressive symptom-domains in major depressive disorder following antidepressant treatment: a randomized clinical trial (2020) (16)
- Insight into mental disorders and suicidal behavior: a qualitative and quantitative multimodal investigation. (2015) (16)
- Suicide, schizophrenia, and schizoid-type psychosis: role of life events and childhood factors. (2011) (16)
- Prefrontal inositol levels and implicit decision-making in healthy individuals and depressed patients (2016) (16)
- Theory of mind in subjects with major depressive disorder: is it influenced by repetitive transcranial magnetic stimulation? (2012) (16)
- Polyglutamine coding genes in bipolar disorder: lack of association with selected candidate loci. (2000) (16)
- Analysis of Features Selected by a Deep Learning Model for Differential Treatment Selection in Depression (2020) (16)
- Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder. (2018) (15)
- Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide (2017) (15)
- A randomized, crossover comparison of ketamine and electroconvulsive therapy for treatment of major depressive episodes: a Canadian biomarker integration network in depression (CAN-BIND) study protocol (2020) (15)
- Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice (2016) (15)
- Polyglutamine tracts: no evidence of a major role in bipolar disorder (1999) (15)
- Age and Haplotype Variations within FADS1 Interact and Associate with Alterations in Fatty Acid Composition in Human Male Cortical Brain Tissue (2012) (15)
- Neural and molecular correlates of psychological pain during major depression, and its link with suicidal ideas (2020) (14)
- Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation (2021) (14)
- Characterization of Vimentin-Immunoreactive Astrocytes in the Human Brain (2020) (14)
- Substance dependence. (1998) (13)
- The miRNome of Depression (2021) (13)
- Suicide and suicide behaviors: A review of transcriptomics and multiomics studies in psychiatric disorders (2020) (13)
- Completed Suicides in a Youth Centres Population (2005) (13)
- DAPP-BQ: factor structure in French Canadians. (2008) (13)
- Ketamine and Esketamine augmentation for suicidal ideation: A randomized, double-blinded clinical trial. (2020) (13)
- Using a simulation centre to evaluate preliminary acceptability and impact of an artificial intelligence-powered clinical decision support system for depression treatment on the physician–patient interaction (2021) (13)
- Early environment and major depression in young adults: A longitudinal study (2008) (13)
- Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells (2020) (13)
- Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response (2021) (12)
- Deep feature extraction of single-cell transcriptomes by generative adversarial network (2020) (12)
- Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients (2021) (12)
- Evidence of Reduced Agmatine Concentrations in the Cerebral Cortex of Suicides (2018) (12)
- Predicting Worsening Suicidal Ideation With Clinical Features and Peripheral Expression of Messenger RNA and MicroRNA During Antidepressant Treatment. (2019) (12)
- Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway (2021) (12)
- Widespread Decrease of Cerebral Vimentin-Immunoreactive Astrocytes in Depressed Suicides (2020) (11)
- Interpersonal Self-Efficacy, Goals, and Problems of Persistently Depressed Outpatients: Prototypical Circumplex Profiles and Distinctive Subgroups (2018) (11)
- Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder (2020) (11)
- Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials (2022) (11)
- Psychiatric services utilization in completed suicides of a youth centres population (2006) (11)
- A systematic evaluation of linkage studies in bipolar disorder (1996) (11)
- Is lithium response related to Gsα levels in transformed lymphoblasts from subjects with bipolar disorder (2001) (11)
- 228. A genome scan using a pharmacogenetic approach indicates a susceptibility locus for BD on 15q14 (2000) (11)
- Association Between Side Effects and Blood microRNA Expression Levels and Their Targeted Pathways in Patients With Major Depressive Disorder Treated by a Selective Serotonin Reuptake Inhibitor, Escitalopram: A CAN-BIND-1 Report (2019) (11)
- Application of microarray outlier detection methodology to psychiatric research (2008) (11)
- Association between hypovitaminosis D and cognitive inhibition impairment during major depression episode. (2018) (10)
- Epigenetic regulation of the kappa opioid receptor gene by an insertion–deletion in the promoter region (2018) (10)
- Perinatal adversity profiles and suicide attempt in adolescence and young adulthood: longitudinal analyses from two 20-year birth cohort studies (2020) (10)
- Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine (2017) (10)
- Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals (2020) (10)
- Estimulação transcraniana por corrente direta: uma alternativa promissora para o tratamento da depressão maior? (2009) (10)
- Examining the role of mother-child interactions and DNA methylation of the oxytocin receptor gene in understanding child controlling attachment behaviors (2020) (10)
- Differences and similarities in instant countertransference towards patients with suicidal ideation and personality disorders. (2020) (10)
- BisQC: an operational pipeline for multiplexed bisulfite sequencing (2014) (10)
- Childhood-maltreatment subtypes in bipolar patients with suicidal behavior: systematic review and meta-analysis (2020) (10)
- Using Epigenetic Tools to Investigate Antidepressant Response. (2018) (10)
- Contribution of birth weight to mental health, cognitive and socioeconomic outcomes: two-sample Mendelian randomisation (2021) (10)
- Brain cortical and subcortical morphology in adolescents with depression and a history of suicide attempt (2021) (10)
- MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings (2020) (10)
- Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression (2019) (9)
- Identifying environmental pathways between irritability during childhood and suicidal ideation and attempt in adolescence: findings from a 20-year population-based study. (2021) (9)
- SNAT1 and a family with high rates of suicidal behavior (2009) (9)
- Evaluating the Clinical Feasibility of an Artificial Intelligence–Powered, Web-Based Clinical Decision Support System for the Treatment of Depression in Adults: Longitudinal Feasibility Study (2021) (9)
- Protective Factors in the Inuit Population of Nunavut: A Comparative Study of People Who Died by Suicide, People Who Attempted Suicide, and People Who Never Attempted Suicide (2018) (9)
- Differential Expression of Ribosomal Genes in Brain and Blood of Alzheimer's Disease Patients. (2015) (9)
- Long-term economic and social outcomes of youth suicide attempts (2021) (9)
- Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder (2018) (9)
- Differential ESR1 Promoter Methylation in the Peripheral Blood—Findings from the Women 40+ Healthy Aging Study (2020) (9)
- Long-term responsiveness to lithium as a pharmacogenetic outcome variable: Treatment and etiologic implications (2003) (9)
- Polyamines and suicide risk (2013) (9)
- Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis (2021) (9)
- Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation (2020) (9)
- Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. (2020) (9)
- Childhood maltreatment and clinical severity of treatment‐resistant depression in a French cohort of outpatients (FACE‐DR): One‐year follow‐up (2020) (8)
- Attempted Suicide Among Students and Young Adults in Montreal, Quebec, Canada: A Retrospective Cross-Sectional Study of Hospitalized and Nonhospitalized Suicide Attempts Based on Chart Review. (2015) (8)
- EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia (2018) (8)
- Dysregulation of the glutamatergic receptors after antidepressant treatment in human neural progenitor cells (2017) (8)
- Noncoding RNAs in Depression. (2017) (8)
- Molecular impacts of childhood abuse on the human brain (2021) (8)
- Evaluating the perceived utility of an artificial intelligence-powered clinical decision support system for depression treatment using a simulation center (2021) (8)
- A Bi-Directional Competitive Interaction between CircHomer1 and Homer1b within the Orbitofrontal Cortex Regulates Reversal Learning (2020) (8)
- Family density of alcoholism and linkage information in the analysis of the COGA data (1999) (8)
- Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients. (2017) (8)
- Sleep quality is associated with vasopressin methylation in pregnant and postpartum women with a history of psychosocial stress (2019) (8)
- Schizophrenia, Other Psychotic Disorders, and Suicidal Behaviour (2011) (8)
- Symptom Dimension of Interest-Activity Indicates Need for Aripiprazole Augmentation of Escitalopram in Major Depressive Disorder: A CAN-BIND-1 Report. (2020) (8)
- Self-critical perfectionism is associated with increases in sympathetic indicators in a controlled laboratory stress paradigm. (2009) (8)
- Pharmacogenetics and mood stabilization in bipolar disorder (2003) (8)
- Approaches and Findings from Gene Expression Profiling Studies of Suicide (2012) (7)
- Oxytocin receptor expression and epigenetic regulation in the anterior cingulate cortex of individuals with a history of severe childhood abuse (2021) (7)
- Disrupting D1-NMDA or D2-NMDA receptor heteromerization prevents cocaine’s rewarding effects but preserves natural reward processing (2021) (7)
- Le suicide chez les hommes de 18 à 55 ans : Trajectoires de vie (2003) (7)
- Machine Learning Analysis of Blood microRNA Data in Major Depression: A Case-Control Study for Biomarker Discovery (2020) (7)
- Developmental trajectories of childhood symptoms of hyperactivity/inattention and suicidal behavior during adolescence (2019) (7)
- Systematic review of mental health symptom changes by sex or gender in early-COVID-19 compared to pre-pandemic (2022) (7)
- Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving FosB and Calcium / Calmodulin-Dependent Protein Kinase II in the Citation (2013) (7)
- [Transcranial direct current stimulation: a promising alternative for the treatment of major depression?]. (2009) (7)
- Characterisation of age and polarity at onset in bipolar disorder (2021) (7)
- Variations in 5-methylcytosine and 5-hydroxymethylcytosine among human brain, blood, and saliva using oxBS and the Infinium MethylationEPIC array (2016) (7)
- Non-CG methylation and multiple epigenetic layers associate child abuse with immune and small GTPase dysregulation (2020) (7)
- Preventing suicide: where are we? (2016) (6)
- Validation study of microRNAs previously associated with antidepressant response in older adults treated for late-life depression with venlafaxine (2020) (6)
- High-resolution capillary gas chromatography in combination with mass spectrometry for quantification of three major polyamines in postmortem brain cortex. (2011) (6)
- Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores (2018) (6)
- Effect of exercise training during pregnancy: maternal and fetal responses of the rat. (1989) (6)
- Is lithium response related to G(s)alpha levels in transformed lymphoblasts from subjects with bipolar disorder? (2001) (6)
- Metabolomic signatures associated with depression and predictors of antidepressant response in humans: A CAN-BIND-1 report (2021) (6)
- A novel liquid-liquid extraction and stable isotope dilution NCI-GC-MS method for quantitation of agmatine in postmortem brain cortex. (2010) (6)
- Contribution of genes and environment to the longitudinal association between childhood impulsive-aggression and suicidality in adolescence. (2019) (6)
- Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications (2020) (6)
- Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach (2022) (6)
- Netrin G1: its downregulation in the nucleus accumbens of cocaine‐conditioned mice and genetic association in human cocaine dependence (2018) (5)
- Integrative DNA Methylation and Gene Expression Analysis in the Prefrontal Cortex of Mexicans Who Died by Suicide (2021) (5)
- The Epigenetics of Depression and Suicide (2011) (5)
- Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions (2022) (5)
- Author Correction: Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior (2017) (5)
- [Restless leg syndrome arousal: clinic, etiology and genetic perspectives] (2002) (5)
- The interaction between oxytocin receptor gene methylation and maternal behavior on children's early theory of mind abilities (2020) (5)
- Global and Site-Specific Changes in 5-Methylcytosine and 5-Hydroxymethylcytosine after Extended Post-mortem Interval (2016) (5)
- Epigenetic Regulation of Synapsin Genes in Mood Disorders (2013) (5)
- Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood. (2021) (5)
- The Role of Epigenetic Dysregulation in Suicidal Behaviors. (2020) (5)
- Genetic association studies of neurotensin gene and restless legs syndrome in French Canadians. (2008) (5)
- Effects of COVID-19 Mental Health Interventions among Community-based Children, Adolescents, and Adults: A Living Systematic Review of Randomised Controlled Trials (2021) (5)
- Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum (2021) (5)
- Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior (2021) (5)
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- Solidaires pour la vie (2020) (0)
- Separated (2020) (0)
- Evaluating the Clinical Feasibility of an Artificial Intelligence-Powered Clinical Decision Support System for Depression Treatment: A Longitudinal Feasibility Study (Preprint) (2021) (0)
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