Guy Sauvageau
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Canadian doctor and researcher
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Guy Sauvageau's Degrees
- Doctorate Medicine Université de Montréal
- PhD Immunology Université de Montréal
Why Is Guy Sauvageau Influential?
(Suggest an Edit or Addition)Guy Sauvageau's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells (2003) (1568)
- HOXB4-Induced Expansion of Adult Hematopoietic Stem Cells Ex Vivo (2002) (769)
- Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b (1998) (709)
- Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. (2010) (677)
- Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. (1995) (648)
- Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. (1994) (587)
- Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal (2014) (387)
- Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. (2002) (377)
- Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia (1997) (365)
- Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis. (1997) (351)
- In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein (2003) (309)
- Defining Roles for HOX and MEIS1 Genes in Induction of Acute Myeloid Leukemia (2001) (305)
- A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia. (2012) (274)
- HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. (2001) (261)
- The Role of HOX Homeobox Genes in Normal and Leukemic Hematopoiesis (1996) (258)
- NUP98–HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice (2001) (247)
- Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. (1999) (242)
- Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. (2005) (221)
- Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. (1997) (208)
- In vitro and in vivo expansion of hematopoietic stem cells (2004) (204)
- Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size. (1999) (187)
- Stage-specific expression of polycomb group genes in human bone marrow cells. (1998) (179)
- Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. (2002) (155)
- An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. (2010) (142)
- A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity (2008) (139)
- GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo. (2016) (135)
- Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. (1996) (132)
- The methyltransferase G9a regulates HoxA9-dependent transcription in AML (2014) (127)
- Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. (1996) (125)
- The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias (2015) (124)
- Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells. (1995) (124)
- EPCR expression marks UM171-expanded CD34+ cord blood stem cells. (2017) (121)
- AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia (2017) (118)
- Identification of small molecules that support human leukemia stem cell activity ex vivo (2014) (117)
- Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia. (2019) (116)
- The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. (2003) (98)
- Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. (2009) (95)
- Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1 (1998) (90)
- Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. (2014) (89)
- Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2. (2012) (88)
- A role for GPx3 in activity of normal and leukemia stem cells (2012) (87)
- Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. (2006) (87)
- The Oncoprotein E2A-Pbx1a Collaborates with Hoxa9 To Acutely Transform Primary Bone Marrow Cells (1999) (87)
- Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. (2005) (87)
- Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study. (2019) (86)
- Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis. (2003) (82)
- Hox homeobox genes as regulators of normal and leukemic hematopoiesis. (1997) (79)
- Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. (2004) (77)
- Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. (2007) (76)
- Genetic programs regulating HSC specification, maintenance and expansion (2004) (76)
- Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect (2001) (76)
- An anticlastogenic function for the Polycomb Group gene Bmi1 (2011) (70)
- High incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia. (2005) (68)
- RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity. (2013) (65)
- Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors. (2016) (64)
- Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers (2016) (63)
- Oncogenic interaction between BCR-ABL and NUP98-HOXA9 demonstrated by the use of an in vitro purging culture system. (2002) (62)
- RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature. (2016) (61)
- The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through beta-catenin-independent signaling. (2008) (61)
- RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity. (2011) (60)
- AP-1 complex is effector of Hox-induced cellular proliferation and transformation (2000) (58)
- SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells (2014) (58)
- Safety and cost-effectiveness of outpatient autologous stem cell transplantation in patients with multiple myeloma. (2013) (58)
- E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells. (2006) (57)
- EN2 is a candidate oncogene in human breast cancer (2005) (57)
- High incidence of invasive aspergillosis associated with intestinal graft-versus-host disease following nonmyeloablative transplantation. (2007) (55)
- Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets (2016) (55)
- Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation. (2006) (54)
- Polycomb Group Genes: Keeping Stem Cell Activity in Balance (2008) (54)
- H3K27M/I mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations. (2017) (52)
- EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. (2015) (48)
- RNA-Seq Reveals Spliceosome and Proteasome Genes as Most Consistent Transcripts in Human Cancer Cells (2013) (47)
- MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia. (2018) (47)
- Genetic characterization of ABT-199 sensitivity in human AML (2018) (46)
- SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism (2017) (45)
- HoxA cluster is haploinsufficient for activity of hematopoietic stem and progenitor cells. (2010) (44)
- A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations. (2010) (43)
- Sustained in vitro trigger of self-renewal divisions in Hoxb4hiPbx1(10) hematopoietic stem cells. (2007) (42)
- Reduction of early B lymphocyte precursors in transgenic mice overexpressing the murine heat-stable antigen. (1996) (41)
- Graft-versus-host disease prophylaxis with tacrolimus and mycophenolate mofetil in HLA-matched nonmyeloablative transplant recipients is associated with very low incidence of GVHD and nonrelapse mortality. (2009) (41)
- Epstein-Barr virus receptor expression on human CD8+ (cytotoxic/suppressor) T lymphocytes. (1990) (40)
- Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes. (2021) (37)
- Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML. (2019) (37)
- Epigenetic regulation of GATA2 and its impact on normal karyotype acute myeloid leukemia (2014) (36)
- High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia (2018) (34)
- Distinct signaling programs control human hematopoietic stem cell survival and proliferation. (2017) (34)
- Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia. (2008) (33)
- High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells. (2016) (30)
- UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity. (2014) (30)
- Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity (2017) (30)
- A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2 (2019) (29)
- Incidence and prognostic value of eosinophilia in chronic graft-versus-host disease after nonmyeloablative hematopoietic cell transplantation. (2011) (29)
- High frequency of germline RUNX1 mutations in RUNX1 mutated AML patients. (2020) (29)
- Entinostat Prevents Leukemia Maintenance in a Collaborating Oncogene‐Dependent Model of Cytogenetically Normal Acute Myeloid Leukemia (2013) (28)
- UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex. (2021) (27)
- Identification of MYC mutations in acute myeloid leukemias with NUP98–NSD1 translocations (2016) (27)
- Evidence for Hox and E2A–PBX1 collaboration in mouse T-cell leukemia (2008) (26)
- Haploinsufficiency screen highlights two distinct groups of ribosomal protein genes essential for embryonic stem cell fate (2015) (25)
- Zfx: At the Crossroads of Survival and Self-Renewal (2007) (25)
- Funding considerations for the disclosure of genetic incidental findings in biobank research (2013) (25)
- UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal (2019) (24)
- Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. (2016) (24)
- Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin (2018) (24)
- The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia (2019) (24)
- Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells. (2019) (24)
- Posttranslational regulation of self-renewal capacity: insights from proteome and phosphoproteome analyses of stem cell leukemia. (2012) (23)
- Are genetic determinants of asymmetric stem cell division active in hematopoietic stem cells? (2004) (23)
- Immunologic thrombocytopenia followed by thrombotic thrombocytopenic purpura in two HIV1 patients (1991) (22)
- Tandem autologous-allogeneic nonmyeloablative sibling transplantation in relapsed follicular lymphoma leads to impressive progression-free survival with minimal toxicity. (2012) (21)
- Haploidentical Stem Cell Transplantation: High Doses of Alloreactive-T Cell Depleted Donor Lymphocytes Administered Post-Transplant Decrease Infections and Improve Survival without Causing Severe Gvhd. (2009) (20)
- Roles for MSI2 and PROX1 in hematopoietic stem cell activity (2011) (20)
- UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells (2018) (20)
- Allodepleted T‐cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft‐versus‐host disease (GVHD) in the absence of GVHD prophylaxis (2019) (19)
- E4F1 is a master regulator of CHK1-mediated functions. (2015) (19)
- Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition. (2019) (18)
- Analysis of Blood Stem Cell Activity and Cystatin Gene Expression in a Mouse Model Presenting a Chromosomal Deletion Encompassing Csta and Stfa2l1 (2009) (18)
- An automated system for delivery of an unstable transcription factor to hematopoietic stem cell cultures (2009) (17)
- Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila. (2017) (16)
- Small molecule regulation of normal and leukemic stem cells (2015) (16)
- A retroviral strategy that efficiently creates chromosomal deletions in mammalian cells (2007) (16)
- Disclosure of incidental findings in cancer genomic research: investigators' perceptions on obligations and barriers (2015) (15)
- Complementary and independent function for Hoxb4 and Bmi1 in HSC activity. (2008) (15)
- Favorable long-term outcome of patients with multiple myeloma using a frontline tandem approach with autologous and non-myeloablative allogeneic transplantation (2016) (14)
- MiSTIC, an integrated platform for the analysis of heterogeneity in large tumour transcriptome datasets (2017) (14)
- The Blood Stem Cell Holy Grail? (2010) (14)
- UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis (2017) (13)
- Reduction in Incidence of Severe Infections by Transplantation of High Doses of Haploidentical T Cells Selectively Depleted of Alloreactive Units (2011) (13)
- Identification of non-cell-autonomous networks from engineered feeder cells that enhance murine hematopoietic stem cell activity. (2013) (13)
- Differences in Epstein-Barr virus (EBV) receptors expression on various human lymphoid targets and their significance to EBV-cell interaction. (1988) (13)
- Evidence that donor intrinsic response to G-CSF is the best predictor of acute graft-vs-host disease following allogeneic peripheral blood stem cell transplantation. (2006) (13)
- HLF Expression Defines the Human Hematopoietic Stem Cell State. (2021) (13)
- C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein. (2011) (12)
- Phase I Clinical Study of Donor Lymphocyte Infusion Depleted of Alloreactive T Cells after Haplotype Mismatched Myeloablative Stem Cell Transplantation To Limit Infections and Malignant Relapse without Causing GVHD. (2006) (10)
- A role for GPx 3 in activity of normal and leukemia stem cells (2012) (10)
- Evaluation of the Impact of Autologous Hematopoietic Stem Cell Transplantation on the Quality of Life of Older Lymphoma Patients. (2019) (9)
- Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia (2021) (9)
- Gfi-1: another piece in the HSC puzzle. (2005) (9)
- A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens (2017) (9)
- Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia (2022) (9)
- Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair (2021) (9)
- UM171-expanded cord blood transplants support robust T cell reconstitution with low rates of severe infections. (2020) (8)
- Targeted variant detection using unaligned RNA-Seq reads (2019) (8)
- Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML (2021) (8)
- Genome-Wide Interrogation of Mammalian Stem Cell Fate Determinants by Nested Chromosome Deletions (2010) (7)
- In vitro stem cell expansion: Stepping closer towards self-renewal (2006) (7)
- Homeobox Gene Networks and the Regulation of Hematopoiesis (2002) (7)
- Cardiac tamponade potentially related to sirolimus following cord blood transplantation (2012) (7)
- Uncovering stemness (2006) (7)
- Bringing a Leukemic Stem Cell Gene Signature into Clinics: Are We There Yet? (2017) (7)
- HLF Expression Defines the Human Haematopoietic Stem Cell State (2020) (6)
- Outcome of autologous hematopoietic stem cell transplant in older patients with B cell lymphoma when selected for fitness and chemosensitive disease. (2019) (6)
- Diphyllobothriasis, a rare cause of profuse diarrhea following autologous transplantation (2009) (6)
- Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells (2011) (6)
- Deregulated expression of HOXB 4 enhances the primitive growth activity of human hematopoietic cells (2002) (6)
- CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia (2022) (6)
- Graft-Versus-Host Disease (Gvhd) Prophylaxis with Tacrolimus and Mycophenolate Mofetil (MMF) in 131 Matched Sibling Nonmyeloablative (NMA) Transplant Recipients: Long-Term Follow-up Confirms Extremely Low Incidence of Acute (a) Gvhd, High Incidence of Extensive Chronic (c) Gvhd and Favorable Disease (2008) (5)
- Effect of monoclonal antibodies to Epstein-Barr virus envelope glycoproteins on Epstein-Barr virus neutralization and binding to target cell receptors. A comparative analysis. (1990) (5)
- Pathways, Processes, and Candidate Drugs Associated with a Hoxa Cluster-Dependency Model of Leukemia (2019) (5)
- Target variant detection in leukemia using unaligned RNA-Seq reads (2018) (4)
- Outcomes in newly diagnosed young or high-risk myeloma patients receiving tandem autologous/allogeneic transplant followed by bortezomib maintenance: a phase II study (2021) (4)
- Single UM171 expanded cord blood transplant is feasible and safe, accelerates engraftment, reduces hospitalization length and most importantly improves HLA matching (2017) (4)
- Newly diagnosed multiple myeloma patients treated with tandem auto‐allogeneic stem cell transplant have better overall survival with similar outcomes at time of relapse compared to patients who received autologous transplant only (2020) (4)
- Late acute renal failure due to bilateral kidney infiltration by ALL as single manifestation of relapse after allogeneic transplantation (2010) (4)
- Nocardiosis in Allogeneic Hematopoietic Stem Cell Transplant Recipients: A Matched Case-Control Study of Risk Factors, Clinical Features and Outcomes (2013) (4)
- Single UM171 Expanded Cord Blood Transplant is Feasible, Safe, and Permits Transplantation of Better HLA Matched Cords with Very Low Transplant Related Mortality (2017) (4)
- Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells (2022) (4)
- Phase I Clinical Trial of Haplotype Mismatched Myeloablative Stem Cell Transplantation: Higher Doses of Donor Lymphocyte Infusions Depleted of Alloreactive Cells Using ATIR May Improve Outcome without Causing GVHD. (2007) (3)
- Bortezomib Consolidation after Nonmyeloablative Allogeneic Stem Cell Transplantation Leads to a High Incidence of Immunophenotypic Complete Response in Young and/or High-Risk Multiple Myeloma Patients (2016) (3)
- Cytofluorometric Study of Epstein-Barr Virus Receptor Expression on Human T Lymphocyte Populations (1987) (3)
- Molecular basis for stem-cell self-renewal. (2004) (3)
- Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting (2019) (3)
- p120E4F-1: A Novel Candidate Factor for Mediating Bmi-1 Function in Hematopoietic Stem Cells. (2004) (3)
- Profound MRD negativity rates after frontline tandem autologous-allogeneic stem cell transplantation followed by bortezomib maintenance in high-risk or young myeloma patients (2019) (3)
- Impact of Carmustine (BCNU) Substitution for Bendamustine in the Conditioning Regimen Prior to Autologous Hematopoietic Cell Transplantation for the Treatment of Lymphoma (2017) (3)
- Real-world outcomes of autologous and allogeneic hematopoietic stem cell transplantation for relapsed/refractory Hodgkin lymphoma in the era of novel therapies: a Canadian perspective (2021) (3)
- UM171 expansion of cord blood improves donor availability and HLA matching for all patients, including minorities. (2022) (3)
- Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia (2021) (2)
- Human hematopoietic stem cells can be expanded ex vivo using recombinant TAT-HOXB4 protein (2005) (2)
- A Functional Screen Identifies Polarity Genes Implicated in HSC Fate (2008) (2)
- Transcriptome Analysis Reveals That G Protein-Coupled Receptors Are Potential Diagnostic Markers or Therapeutic Targets in Acute Myeloid Leukemia (2015) (2)
- Revealing the Interplay of Extrinsic Versus Intrinsic Regulators of Self-Renewal in Hoxb4-Transduced HSCs. (2004) (2)
- Effective Expansion and Engraftment Of Nonhuman Primate CD34+Hematopoietic Stem Cells After Co-Culture With The Small Molecule UM171 (2013) (2)
- Tandem Autologous-Allogeneic Nonmyeloablative Sibling Transplant in Relapsed Follicular Lymphoma Leads to Impressive Progression Free Survival with Minimal Toxicity. (2009) (2)
- Differential expression of homeobox genes in functionally distinct CD 34 + subpopulations of human bone marrow cells ( cDNA / hematopoiesi / Hox genes / reverse transcription PCR / stem cell-specdfc genes ) (2004) (2)
- Donor Lymphocyte Infusions Depleted of Alloreactive T Cells Decrease Infections without Causing GVHD After Haplotype Mismatched Myeloablative Stem Cell Transplantation (2009) (2)
- Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival (2018) (2)
- UM171 Is a Novel and Potent Agonist Of Human Hematopoietic Stem Cell Renewal (2013) (2)
- Multi-Log Clonal Ex-Vivo Expansion of Long Term Lympho-Myeloid Hematopoietic Stem Cells by Nup98-Hox Fusion Genes. (2004) (2)
- H3 mutations promote context-dependent transformation in acute myeloid leukemia with RUNX1 alterations. Running title: H3K27 mutations cooperate with RUNX1 alterations (2017) (2)
- UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections (2020) (2)
- First Line Allogeneic Stem Cell Transplantation in Mantle Cell Lymphoma (MCL). (2009) (2)
- Single UM171‐expanded cord blood transplant can cure severe idiopathic aplastic anemia in absence of suitable donors (2020) (2)
- Modeling of Pediatric Acute Megakaryoblastic Leukemia Using Cord Blood Stem/Progenitor Cells (2016) (1)
- High Progression-Free Survival At 10 Years After Tandem Autologous/Nonmyeloablative Allogeneic Transplants For Multiple Myeloma In a Cohort Of 93 Patients: Impact Of Disease Remission Status At Transplant and Chronic Graft-Versus-Host Disease (2013) (1)
- Prompt Treatment of Respiratory Syncytial Virus with Inhaled Ribavirin and IVIG in High Risk Allogeneic Stem Cell Transplant Recipients Significantly Diminishes Mortality (2013) (1)
- Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: Scoping Literature Review (2020) (1)
- A Functional In Vivo RNAi screen Involving Jumonji C Domain Containing Candidates Unravels Kdm5b As a Negative Modulator of Hematopoietic Stem Cell Self-Renewal (2011) (1)
- Favorable long-term survival of patients with multiple myeloma using a frontline tandem approach with autologous and nonmyeloablative allogeneic transplantation (2015) (1)
- Gpx3 Determines Competitiveness of Normal and Leukemic Stem Cells. (2010) (1)
- Donor Age and Non-Relapse Mortality: Study of Their Association after HLA-Matched Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome (2022) (1)
- Regulation of mouse embryonic stem cell fate by ribosomal proteins (2013) (1)
- marrow cells induces stem cell expansion associatedHoxa9 gene in bone - Overexpression of the myeloid leukemia (2013) (1)
- Committed Hemopoietic Progenitors, Not Stem Cells, are the Principal Responders to Hox Gene Transduction (2017) (1)
- Ectopic Expression of Mutated HOXB4 Proteins with Increased Intracellular Stability Affects Both Long and Short Term Hematopoietic Reconstitution. (2006) (1)
- Differential Expression and Re-Localization of Potential Cell Fate Determinants in Hematopoietic and Leukemia Stem Cells. (2007) (1)
- Genetic Landscape of Electron Transport Chain Complex I Dependency in Acute Myeloid Leukemia (2019) (1)
- Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia (2018) (1)
- Ex Vivo Expansion of Human SCID-Repopulating Cells Using Recombinant TAT-HOXB4 Protein. (2005) (1)
- MYELOID NEOPLASIA EVI 1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations (2014) (1)
- Killer granzyme B linked to N-myc- and c-myc-dependent HSC survival: isn't that comyc? (2008) (1)
- HMGA2 expression defines a subset of human AML with immature transcriptional signature and vulnerability to G2/M inhibition (2022) (1)
- Mutational and Transcriptomic Landscape of AML with Core-Binding Factor Rearrangements (2015) (1)
- Transcriptional Landscape of APL Identifies Aberrant Podoplanin Expression As a Defining Feature and Missing Link for the Bleeding Disorder of This Disease (2016) (1)
- Pneumatosis Coli Associated to Severe Intestinal Graft Versus Host Disease Following Hematopoietic Cell Transplantation: Risk Factors and Dismal Outcome (2013) (1)
- Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression (2018) (1)
- High Dose Valacyclovir Is Highly Effective to Prevent Cytomegalovirus and Other Herpes Viruses Viremia After Allogeneic Stem Cell Transplantation. (2009) (1)
- Ex Vivo Generation and Infusion of Anti-Minor Histocompatibility Antigen Expanded T Cells for Patients Who Relapse after Allogeneic HLA-Matched Stem Cell Transplantation (2022) (0)
- Impact of Graft CD34 Cell Dose on Chronic Graft-Versus-Host Disease (cGVHD) and Predictive Values of CD3 Cell Dose and Day 56 Chimerism on Survival in Nonmyeloablative (Nma) Allogeneic Hematopoietic Stem Cell Transplant (HSCT) (2012) (0)
- Myeloma Patients Relapsing after First Line Treatment with Tandem Auto/Allo Transplant or Auto Transplant Only Have Similar Outcomes. (2020) (0)
- demonstrated by the use of an in vitro purging culture system Oncogenic interaction between BCR-ABL andNUP98-HOXA9 (2013) (0)
- Tandem Autologous-Nonmyeloablative (NMA) Allogeneic(Allo) Transplant (Tx) in Newly Diagnosed Multiple Myeloma (MM) Leads to Improved Survival When Compared to Conventional Allogeneic Transplant (2008) (0)
- A High-Throughput Screen to Identify Compounds Preserving Primary Human AML Stem Cells Ex-Vivo, (2011) (0)
- I s a M aster R egulator of C HK1-Mediated F unctions (2015) (0)
- Abstract 1509: RUNX1 dosage dictates gene signature andin vitroresponse to glucocorticoids in acute myeloid leukemia (2017) (0)
- Bortezomib Consolidation after Tandem Auto-Allogeneic Transplantation: High Incidence of Immunophenotypic Complete Response in Young and/or High-Risk Newly Diagnosed Myeloma Patients (2017) (0)
- MYELOID NEOPLASIA GPR56 identi fi es primary human acute myeloid leukemia cells with high repopulating potential in vivo (2016) (0)
- The Bmi1-interacting protein E4f1 is vital for hematopoietic stem/progenitor cell function (2013) (0)
- A Novel Osteoclastic Network Determines In Vitro Niche for Mouse and Human Hematopoietic Stem Cells (2011) (0)
- The Novel Leukemia Stem Cell Marker GPR56 Discriminates Leukemic Subclones with Divergent Stem Cell Properties in Human Acute Myeloid Leukemia (2015) (0)
- UM171 Expansion Overcomes Shortcomings of Cord Blood Transplantation While Maintaining Benefits (2020) (0)
- Improved Outcomes of UM171-Expanded Cord Blood Transplantation Compared with Other Graft Sources: Real World Evidence (2022) (0)
- Chemo-Transcriptomic Analysis of Complex Karyotype AML Reveals Increased Expression of Cell Cycle Components and Exquisite Dependency on Polo-like Kinase 1 (2016) (0)
- Pyrimido-Indole Derivatives Are Novel Agonists of Human Cord Blood Hematopoietic Stem Cell Self-Renewal (2014) (0)
- BMI1 Interacts with FANCD2 at DNA Lesions and Prevents Chromosome Breaks (2008) (0)
- 197: Mutated Hoxb4 results in increased intracellular stability affecting both long and short term hematopoietic reconstitution (2007) (0)
- Collagen and Elastin Degradation Products as Potential Biomarkers for Chronic Graft-Versus-Host Disease (cGVHD). (2009) (0)
- Podoplanin Expression in the Bleeding Complications of Acute Promyelocytic Leukemias (2017) (0)
- Substitution of Carmustine for Bendamustine in the Transplant Conditioning Regimen Improves Survival in Relapsed/Refractory Lymphoma Patients (2021) (0)
- Stem cells: Cord-blood cells made plentiful (2014) (0)
- Identification of a Novel Cyclin K Degrader Molecule with Selective Anti-AML Activity (2022) (0)
- UM171 Induces a Homeostatic Inflammatory Response Supporting Human HSC Self-Renewal (2019) (0)
- Disruption of Intracellular Metal Homeostasis As a Vulnerability in SF3B1 Mutated AML (2022) (0)
- Policy Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: A Scoping Literature Review (Preprint) (2020) (0)
- Expression and function of Hox genes in normal and leukemic hematopoiesis (1997) (0)
- Impact of Implementing a Bendamustine-based Conditioning Regimen on outcomes of Autologous Stem Cell Transplant in Lymphoma while Novel Cellular Therapies Emerge. (2022) (0)
- A Search for Genes Specifying HSCs through the Development of a New Retroviral-Based System That Creates Nested Deletions in ES cells. (2004) (0)
- Manipulating Stem Cells for Therapeutic Expansion. (2009) (0)
- Identification of Lats 1 As a Putative Tumor Suppressor in HoxA9/Meis Induced Leukemia (2011) (0)
- Baseline Acute Myeloid Leukemia Prognosis Models using Transcriptomic and Clinical Profiles by Studying the Impacts of Dimensionality Reductions and Gene Signatures on Cox-Proportional Hazard (2022) (0)
- Favorable Long-Term Survival of Newly Diagnosed Multiple Myeloma Patients Using a Frontline Outpatient Tandem Approach (2016) (0)
- Recombinant TAT-HOXB4 Protein Promotes Ex Vivo Expansion of Primitive Human Hematopoietic Cells. (2004) (0)
- Acute myeloid leukemia therapeutic target deconvolution by compound clustering and synergistic fingerprinting (2016) (0)
- 3019 – CRISPR-BASED ENGINEERING OF A REPORTER ALLELE DEMONSTRATES THAT HLF EXPRESSION DEFINES THE HUMAN HAEMATOPOIETIC STEM CELL STATE (2020) (0)
- High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia (2018) (0)
- Deep Multi-Omics Profiling in Cytogenetically Poor-Risk AML (2022) (0)
- proteome and phosphoproteome analyses of stem cell leukemia Posttranslational regulation of self-renewal capacity: insights from (2012) (0)
- An exchange of alternative ATPases within BAF complexes accompanies the transition from hemopoietic stem cell quiescence to proliferation (2014) (0)
- 3058 – SURFACE PROTEOMICS REVEALS NOVEL POTENTIAL AML ANTIGENS FOR IMMUNOTHERAPEUTIC TARGETING (2020) (0)
- Minimal Residual Disease Evaluation Using 8-Color Flow Cytometry Predicts Risk of Relapse in High-Risk and/or Young Myeloma Patients Who Receive Bortezomib Consolidation after Frontline Tandem Transplantation (2018) (0)
- AML with EVI1 rearrangements are characterized by SF3B1 and IKZF1 mutations and distinct expression of MECOM isoforms (2014) (0)
- Baf250a Is a Regulator of HSC Populations. (2009) (0)
- Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia (2022) (0)
- in Hoxb cluster mutant fetal liver cells Analysis of HSC activity and compensatory Hox gene expression profile (2013) (0)
- Identification of MEIS-PBX inhibitors as potential anti-leukemic agents using a high-throughput bret-based assay (2013) (0)
- Integrin-α3 Is a New Marker of Long-Term Hematopoietic Stem Cells in Ex Vivo Expanded Cells (2018) (0)
- Pre-Transplant Remission Status and Peripheral Blood Stem Cell Graft Contribute To Long-Term Outcome After Myeloablative Sibling-Donor Allogeneic Transplant For Multiple Myeloma (2013) (0)
- Autologous Bone Marrow Transplant after Failed Peripheral Blood Stem Cell Mobilization Does Not Adversely Affect Engraftment or Transplant Related Toxicity. (2005) (0)
- C-terminal domain of MEIS 1 converts PKNOX 1 ( PREP 1 ) into a HOXA 9-collaborating oncoprotein (2011) (0)
- HEMATOPOIESIS AND STEM CELLS Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells (2015) (0)
- Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Oxphos Dependency in Acute Myeloid Leukemia (2019) (0)
- Histone Demethylases as Modulators of Hematopoietic Cell Fate. (2009) (0)
- Identification of Novel Cell Surface Therapeutic Targets for KMT2A-Rearranged Acute Myeloid Leukemia (2022) (0)
- The EBMT Disease Risk Stratification System (DRSS) Allows Prediction of Relapse after Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndrome (2022) (0)
- Researchers Discuss MLL-Rearranged Acute Myeloid Leukemias (2015) (0)
- Engineering stem cell fate for drug development and therapy (2017) (0)
- NGS-Based Detection Of Multiple RAS-Mutated Clones In MLL-Rearranged Leukemias Suggests Strong Oncogenic Collaboration (2013) (0)
- A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene (2021) (0)
- Bortezomib Consolidation after Frontline Auto-Allogeneic Transplant: Low Toxicity and Frequent Immunophenotypic Complete Responses in High-Risk or Young Myeloma Patients (2018) (0)
- UM171 Modified Cord Blood Achieves Excellent Survival and Disease Control after 2 Years of Follow-up in High and Very High Risk Malignancies (2019) (0)
- Expanding the indications for ibrutinib : complete remission obtained by induction with ibrutinib followed by consolidative aHSCT in refractory primary CNS lymphoma (2020) (0)
- HEMATOPOIESIS AND STEM CELLS EPCR expression marks UM 171-expanded CD 34 1 cord blood stem cells (2017) (0)
- Ubap2l-Bmi-1-Rnf2 Define a Novel Polycomb Complex Essential For Self-Renewal Of Hematopoietic Stem Cells (2013) (0)
- Bortezomib Consolidation after Allogeneic Nonmyeloablative Transplantation to Improve Outcome in Poor Prognosis Multiple Myeloma Patients: A Preliminary Safety Report (2016) (0)
- New strategies for targeting leukemia stem cells (2017) (0)
- The Number of CD34+ Cells in Peripheral Blood Pre Leukapheresis of Allogeneic Stem Cell Donors is Related to Donor Demographic and Hematologic Factors on the Day of Collection. Results of a Single Center Stem Cell Collection Validation Study (2011) (0)
- Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia (2022) (0)
- Exploring tumor biology via integrated analysis of tumor transcriptome datasets with MiSTIC (2016) (0)
- Novel Targeting Strategies for Leukemia-Initiating Cells in Myeloid Neoplasms (2013) (0)
- Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB (2018) (0)
- Differential Gene and MicroRNA Expression In a HOXA9-MEIS1 Model of Leukemia (2010) (0)
- Genetic Interaction between SCL and c-Kit in Hematopoietic Cell Survival. (2005) (0)
- A NUP98-HOX Fusion Gene Containing the Homeodomain of HOXA10 Promotes Significant Expansion of Primitive Human Hematopoietic Cells in Extended Cultures. (2006) (0)
- 3052 – HIGH-EFFICIENCY CRISPR-MEDIATED HDR GENOME EDITING IN CD34+ CELLS FROM HUMAN CORD BLOOD (2022) (0)
- 1023 – THE IMPORTANCE OF STEM CELL EXPANSION IN TOMORROW'S MEDICINE (2022) (0)
- Exploring small molecules to expand human stem cells for transplantation (2014) (0)
- High dose valacyclovir is highly effective to prevent cytomegalovirus and other herpes viruses viremia (2010) (0)
- Single UM171‐Expanded Cord Blood Transplants Support Robust T‐Cell Reconstitution with Low Rates of Severe Infections (2020) (0)
- Effectiveness of Continuous Infusion of Methylprednisolone for Prevention of Antithymocyte Globulin Infusion-Related Reactions in Preparative Regimens for Allogeneic Hematopoietic Cell Transplantation (2018) (0)
- Mechanisms and Technologies Towards Expanding Hematopoietic Stem Cells for Transplantation (2020) (0)
- Targeting pre-leukemic stem cells in T-acute lymphoblastic leukemia (2015) (0)
- Long non-coding RNA expression in normal and leukemic human blood samples: Towards the identification of novel biomarkers and hematopoietic regulators (2014) (0)
- CEACAM1 is a novel culture-compatible surface marker of expanded long-term reconstituting hematopoietic stem cells (2022) (0)
- Radiation boosts immunotherapy. (2014) (0)
- 2024 – GPRC5C IS CRITICAL FOR HEALTHY HEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA (2022) (0)
- 3114 – HMGA2 OVEREXPRESSION CONFERS SENSITIVITY TO G2/M INHIBITORS IN ACUTE MYELOID LEUKEMIA (2020) (0)
- Screen for Small Molecules Capable of Expanding Human Hematopoietic Stem Cell Ex Vivo (2011) (0)
- Bortezomib maintenance after allogeneic transplantation in newly diagnosed myeloma patients results in decreased incidence and severity of chronic GVHD. (2022) (0)
- 49: Haplotype mismatched myeloablative stem cell transplantation: Phase I clinical trial of donor lymphocyte infusion depleted of alloreactive T cells to limit infections and malignant relapse without causing GVHD (2007) (0)
- ETO2 Controls Hematopoietic Stem Cell Expansion. (2009) (0)
- A Pilot Study of UM171 Expanded Cord Blood Grafts for Tandem Auto/Allogeneic Stem Cell Transplant in High and Very High-Risk Myeloma Patients (2023) (0)
- 79. Development and Validation of a Globally Portable Platform for Lentivirus Mediated Hematopoietic Stem Cell Gene Therapy (2015) (0)
- Lats 1 is a putative tumor suppressor in Hoxa9 / Meis induced leukemia (2013) (0)
- Defining Candidate Oncogenes Leading to Increased Susceptibility to Leukemia in eed Mutant Mice. (2005) (0)
- PCN49 COST-EFFECTIVENESS MODEL COMPARING EXPANDED UMBILICAL CORD BLOOD TRANSPLANTS WITH OTHER HSCT STRATEGIES FOR PATIENTS WITH HAEMATOLOGICAL MALIGNANCIES (2019) (0)
- An RNA Interference Screen Identifies the Cell Fate Determinants Msi2 and Prox1 as Novel Regulators of Hematopoietic Stem Cell Self-Renewal. (2009) (0)
- A Point-of-Care Platform for Hematopoietic Stem Cell Gene Therapy (2015) (0)
- IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics (2022) (0)
- 3082 – EXPLORING GLUCOCORTICOID SENSITIVITY MODULATORS IN HUMAN ACUTE MYELOID LEUKEMIA (2020) (0)
- Faculty Opinions recommendation of Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment. (2007) (0)
- induction and a key role for Hoxa gene activation Molecular dissection of Meis1 reveals 2 domains required for leukemia (2013) (0)
- embryonic stem cells differentiated in vitro Overexpression of HOXB4 enhances the hematopoietic potential of (2011) (0)
- Ezh2 Is An Essential Regulator Of T-Cell Development and Oncogenic Transformation (2013) (0)
- An RNA Interference Screen Reveals Fate Determinants Implicated in Asymmetric Cell Division as Potential Regulators of Hematopoietic Stem Cell Self-Renewal (2008) (0)
- Expression and function of Hox homeobox transcription factors in early hematopoiesis (1995) (0)
- Abstract 25 ECTmatch: Optimizing Small-Scale Cord Blood Banking Through HLA Analysis (2022) (0)
- High Expression of SPAG1 Is Associated with a Worse Clinical Outcome in Intermediate Risk Acute Myeloid Leukemia That Can be Partially Overcome By Hematopoietic Stem Cell Transplantation (2018) (0)
- Pharmacoeconomic Impact and Transplant Outcome Associated to Carmustine (BCNU) Substitution with Bendamustine (Be) in the Conditioning Regimen Prior to Autologous Stem Cell Transplantation for Lymphoma Treatment (2018) (0)
- OP0243 Single Nucleotide Polymorphisms (SNP) in The IL-4 Receptor, IL-4, and CD40 Loci and Outcome Prediction in Patients with Early Immune-Mediated Inflammatory Polyarthritis (2016) (0)
- Deterministic Trigger of Self-Renewal in Expanded HSCs Expressing Hoxb4 + Antisense Pbx1. (2005) (0)
- Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia (2019) (0)
- Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia (2019) (0)
- Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids (2018) (0)
- Coordination of Pro- and Anti-Inflammatory Signals Determine Human Hematopoietic Stem and Progenitor Cell Expansion (2018) (0)
- The Hox a Locus Is Strongly Targeted by MMLV in an E2a-PBX1 Induced B-Cell Leukemia Model. (2004) (0)
- Targeted therapy in aml: looking beyond mutations with leucegene project (2016) (0)
- Discovery may hike stem cell transplants. (2014) (0)
- Molecular Dissection of Nup98-HoxA9 Oncogenic Activity Using Drosophila (2008) (0)
- P451: PRMT2: AN ANTI-INFLAMMATORY EPIGENETIC FACTOR INVOLVED IN ACUTE MYELOID LEUKEMIA AGGRESSIVENESS (2022) (0)
- Zoology: Clock ticks for tiny group of fish (2014) (0)
- SCL and Its Partner E2A Are Required for Long-Term Stem Cell Activity. (2006) (0)
- Perturbation Of Gpsm2/Lgn Enhances Haematopoietic Stem Cell Function (2013) (0)
- Identification of Novel Antigens for Normal Karyotype Triple Mutated Acute Myeloid Leukemia (2022) (0)
- Physicians Abstracts (2017) (0)
- A 9-Gene Expression Signature Identifies Patients with Core-Binding Factor Acute Myeloid Leukemia at High Risk of Relapse after Achieving Complete Remission (2019) (0)
- Identification of Oncogenic Collaborators Providing Insights into the Tumor Suppressing Function of the Eed Polycomb Group (PcG) Gene. (2004) (0)
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