Howard Davis Thames
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Philosophy Biology
Howard Davis Thames's Degrees
- Doctorate Medicine Stanford University
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(Suggest an Edit or Addition)Howard Davis Thames's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Defining biochemical failure following radiotherapy with or without hormonal therapy in men with clinically localized prostate cancer: recommendations of the RTOG-ASTRO Phoenix Consensus Conference. (2006) (2358)
- Changes in early and late radiation responses with altered dose fractionation: implications for dose-survival relationships. (1982) (821)
- Direct evidence that prostate tumors show high sensitivity to fractionation (low α/β ratio), similar to late-responding normal tissue (2002) (592)
- An 'incomplete-repair' model for survival after fractionated and continuous irradiations. (1985) (481)
- Radiation therapy for clinically localized prostate cancer: a multi-institutional pooled analysis. (1999) (463)
- Time-dose factors in radiotherapy: a review of the human data. (1990) (406)
- Accelerated fractionation vs hyperfractionation: rationales for several treatments per day. (1983) (401)
- Locoregional recurrence patterns after mastectomy and doxorubicin-based chemotherapy: implications for postoperative irradiation. (2000) (374)
- A new isoeffect curve for change in dose per fraction. (1983) (344)
- Repair capacity and kinetics of human skin during fractionated radiotherapy: erythema, desquamation, and telangiectasia after 3 and 5 year's follow-up. (1989) (338)
- Breast conservation after neoadjuvant chemotherapy: the MD Anderson cancer center experience. (2004) (295)
- Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung cancer receiving concomitant chemoradiotherapy. (2010) (277)
- Long-term multi-institutional analysis of stage T1-T2 prostate cancer treated with radiotherapy in the PSA era. (2003) (270)
- Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue. (2002) (261)
- Accelerated fractionation in the radiation treatment of head and neck cancer. A critical comparison of different strategies. (1988) (253)
- Clinical radiobiology of malignant melanoma. (1989) (226)
- Direct analysis of quantal radiation response data. (1986) (218)
- Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study. (1989) (216)
- Evidence for individual differences in the radiosensitivity of human skin. (1992) (204)
- Comparison of alternative biochemical failure definitions based on clinical outcome in 4839 prostate cancer patients treated by external beam radiotherapy between 1986 and 1995. (2003) (201)
- Tumor volume: a basic and specific response predictor in radiotherapy. (1998) (199)
- Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis. (2016) (197)
- Response to preoperative chemoradiation increases the use of sphincter‐preserving surgery in patients with locally advanced low rectal carcinoma (2003) (185)
- PSA nadir predicts biochemical and distant failures after external beam radiotherapy for prostate cancer: a multi-institutional analysis. (2004) (183)
- Correlation of smoking history and other patient characteristics with major complications of pelvic radiation therapy for cervical cancer. (2002) (179)
- Clinical radiobiology of squamous cell carcinoma of the oropharynx. (1991) (176)
- The tumor volume and clonogen number relationship: tumor control predictions based upon tumor volume estimates derived from computed tomography. (1995) (169)
- Impact of spinal cord repair kinetics on the practice of altered fractionation schedules. (1992) (162)
- Clinical evidence for tumor clonogen regeneration: interpretations of the data. (1991) (159)
- Pre-treatment number of clonogenic cells and their radiosensitivity are major determinants of local tumour control after fractionated irradiation. (2007) (150)
- Breast conservation after neoadjuvant chemotherapy (2005) (149)
- Investigation of bladder dose and volume factors influencing late urinary toxicity after external beam radiotherapy for prostate cancer. (2007) (136)
- Improved biochemical relapse-free survival with increased external radiation doses in patients with localized prostate cancer: the combined experience of nine institutions in patients treated in 1994 and 1995. (2003) (136)
- Hyperfractionated radiotherapy of human tumors: overview of the randomized clinical trials. (1997) (135)
- HPV16 DNA status is a strong prognosticator of loco-regional control after postoperative radiochemotherapy of locally advanced oropharyngeal carcinoma: results from a multicentre explorative study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). (2014) (129)
- Definitions of biochemical failure that best predict clinical failure in patients with prostate cancer treated with external beam radiation alone: a multi-institutional pooled analysis. (2005) (129)
- Tissue repair capacity and repair kinetics deduced from multifractionated or continuous irradiation regimens with incomplete repair. (1984) (126)
- Can modest escalations of dose be detected as increased tumor control? (1992) (126)
- The addition of continuous infusion 5-FU to preoperative radiation therapy increases tumor response, leading to increased sphincter preservation in locally advanced rectal cancer. (2003) (124)
- Keynote address—the problem: Tumor radioresistance in clinical radiotherapy (1982) (123)
- Tumor volume and local control probability: clinical data and radiobiological interpretations. (1996) (121)
- Syngeneic and allogeneic bone marrow engraftment after total body irradiation: dependence on dose, dose rate, and fractionation. (1991) (118)
- Effect of dose-rate on total body irradiation: lethality and pathologic findings. (1985) (117)
- Fractionation parameters for human tissues and tumors. (1989) (117)
- Indium-111-capromab pendetide radioimmunoscintigraphy and prognosis for durable biochemical response to salvage radiation therapy in men after failed prostatectomy. (2003) (114)
- How well is the probability of tumor cure after fractionated irradiation described by Poisson statistics? (1990) (114)
- Repopulation of FaDu human squamous cell carcinoma during fractionated radiotherapy correlates with reoxygenation. (2001) (108)
- Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(−) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG (2016) (105)
- Fractionation sensitivity of a functional endpoint: impaired shoulder movement after post-mastectomy radiotherapy. (1989) (105)
- Pimonidazole labelling and response to fractionated irradiation of five human squamous cell carcinoma (hSCC) lines in nude mice: the need for a multivariate approach in biomarker studies. (2006) (102)
- The role of overall treatment time in the outcome of radiotherapy of prostate cancer: an analysis of biochemical failure in 4839 men treated between 1987 and 1995. (2010) (101)
- HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). (2016) (100)
- Late radiation response of kidney assayed by tubule-cell survival. (1986) (99)
- Comparison of rectal dose-wall histogram versus dose-volume histogram for modeling the incidence of late rectal bleeding after radiotherapy. (2004) (98)
- Protective effects of S-2-(3-aminopropylamino)ethylphosphorothioic acid against radiation damage of normal tissues and a fibrosarcoma in mice. (1982) (97)
- Decreased repopulation as well as increased reoxygenation contribute to the improvement in local control after targeting of the EGFR by C225 during fractionated irradiation. (2005) (94)
- Does incomplete repair explain the apparent failure of the basic LQ model to predict spinal cord and kidney responses to low doses per fraction? (1988) (94)
- Pathologic tumor size and lymph node status predict for different rates of locoregional recurrence after mastectomy for breast cancer patients treated with neoadjuvant versus adjuvant chemotherapy. (2002) (92)
- Direct estimation of latent time for radiation injury in late-responding normal tissues: gut, lung, and spinal cord. (1989) (88)
- Radiobiological hypoxia, histological parameters of tumour microenvironment and local tumour control after fractionated irradiation. (2010) (87)
- Dose-survival characteristics of mouse jejunal crypt cells. (1981) (87)
- Is the α/β ratio for prostate cancer low? (2001) (87)
- A generalized formulation of the 'incomplete-repair' model for cell survival and tissue response to fractionated low dose-rate irradiation. (1990) (87)
- Randomized phase III study of chemoradiation with or without amifostine for patients with favorable performance status inoperable stage II-III non-small cell lung cancer: preliminary results. (2002) (87)
- Definitive radiotherapy for squamous cell carcinoma of the tonsillar fossa. (1989) (83)
- Tumor radioresponsiveness versus fractionation sensitivity. (1986) (80)
- Early and late normal-tissue injury after postmastectomy radiotherapy alone or combined with chemotherapy. (1989) (80)
- The relationship of acute to late skin injury in 2 and 5 fraction/week γ-ray therapy (1977) (79)
- Recovery from radiation damage in mouse lung: interpretation in terms of two rates of repair. (1993) (79)
- The effect of patient-to-patient variability on the accuracy of predictive assays of tumor response to radiotherapy: a theoretical evaluation. (1989) (79)
- Prediction of clonogenic cell survival curves based on the number of residual DNA double strand breaks measured by γH2AX staining (2009) (78)
- Recursive partitioning analysis of locoregional recurrence patterns following mastectomy: implications for adjuvant irradiation. (2001) (78)
- Variations in radiation sensitivity and repair among different hematopoietic stem cell subsets following fractionated irradiation. (1995) (78)
- Estimation of α/β for late rectal toxicity based on RTOG 94-06. (2011) (78)
- Multifraction radiation response of mouse lung. (1985) (77)
- Repair in mouse lung between multiple small doses of X rays. (1983) (77)
- Diverse effects of combined radiotherapy and EGFR inhibition with antibodies or TK inhibitors on local tumour control and correlation with EGFR gene expression. (2011) (77)
- Is the rate of repair of radiation-induced sublethal damage in rat spinal cord dependent on the size of dose per fraction? (1987) (77)
- Preclinical evaluation of molecular-targeted anticancer agents for radiotherapy. (2006) (77)
- Dose-volume response analyses of late rectal bleeding after radiotherapy for prostate cancer. (2004) (76)
- The kinetics of repair in mouse lung after fractionated irradiation. (1987) (76)
- Does Unintentional Splenic Radiation Predict Outcomes After Pancreatic Cancer Radiation Therapy? (2017) (74)
- Ultraviolet A does not induce melanomas in a Xiphophorus hybrid fish model (2010) (74)
- Radiation-induced lung damage after thoracic irradiation for Hodgkin's disease: the role of fractionation. (1995) (73)
- Test of equal effect per fraction and estimation of initial clonogen number in microcolony assays of survival after fractionated irradiation. (1980) (71)
- Fractionation response and repair kinetics of radiation-induced heart failure in the rat. (1992) (71)
- New anticancer agents: in vitro and in vivo evaluation. (2005) (70)
- Biological bases for high RBE values for late effects of neutron irradiation. (1982) (69)
- The results of colorectal cancer treatment by p53 status (2001) (66)
- Repair capacity and kinetics for human mucosa and epithelial tumors in the head and neck: clinical data on the effect of changing the time interval between multiple fractions per day in radiotherapy. (1996) (66)
- Effect-independent measures of tissue responses to fractionated irradiation. (1984) (66)
- High‐affinity triplex‐forming oligonucleotide target sequences in mammalian genomes (2007) (65)
- Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition. (2005) (63)
- Late rectal toxicity on RTOG 94-06: analysis using a mixture Lyman model. (2010) (63)
- Clinically relevant pneumonitis after sequential paclitaxel-based chemotherapy and radiotherapy in breast cancer patients. (2004) (63)
- The impact of young age on locoregional recurrence after doxorubicin-based breast conservation therapy in patients 40 years old or younger: How young is "young"? (2006) (62)
- Protection of acute and late radiation damage of the gastrointestinal tract by WR-2721. (1986) (62)
- Spatial and temporal patterns of expression of epidermal growth factor, transforming growth factor alpha and transforming growth factor beta 1-3 and their receptors in mouse jejunum after radiation treatment. (1997) (61)
- Fractionation sensitivity and latency of telangiectasia after postmastectomy radiotherapy: a graded-response analysis. (1990) (60)
- Exploratory study of the prognostic value of microenvironmental parameters during fractionated irradiation in human squamous cell carcinoma xenografts. (2011) (60)
- Activation of the Canonical Wnt/β-Catenin Pathway in ATF3-Induced Mammary Tumors (2011) (58)
- The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis (2008) (58)
- Biochemical and clinical significance of the posttreatment prostate‐specific antigen bounce for prostate cancer patients treated with external beam radiation therapy alone (2006) (57)
- The challenge of p53 as prognostic and predictive factor in gliomas. (2000) (56)
- Does tumor control decrease by prolonging overall treatment time or interrupting treatment in laryngeal cancer (1995) (56)
- Repair kinetics in tissues: alternative models. (1989) (55)
- Fractionation sensitivities and dose-control relations of head and neck carcinomas: analysis of the randomized hyperfractionation trials. (1999) (55)
- Dose response of squamous cell carcinomas of the upper respiratory and digestive tracts. (1980) (54)
- Cancer stem cells and radiotherapy (2009) (53)
- Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model. (2007) (52)
- Does variation in the in vitro cellular radiosensitivity explain the shallow clinical dose-control curve for malignant melanoma? (1990) (52)
- Heterogeneity in hyperthermic sensitivities of rat 13762NF mammary adenocarcinoma cell clones of differing metastatic potentials. (1982) (51)
- Cluster model analysis of late rectal bleeding after IMRT of prostate cancer: a case-control study. (2006) (51)
- The high steepness of dose-response curves for late-responding normal tissues. (1989) (51)
- Radiation dose-fractionation and dose-rate relationships for long-term repopulating hemopoietic stem cells in a murine bone marrow transplant model. (1993) (51)
- Frequency of first metastatic events in breast cancer: implications for sequencing of systemic and local-regional treatment. (1999) (50)
- GTV differentially impacts locoregional control of non-small cell lung cancer (NSCLC) after different fractionation schedules: subgroup analysis of the prospective randomized CHARTWEL trial. (2013) (49)
- Dynamics of tumor cell clonogen repopulation in a murine sarcoma treated with cyclophosphamide. (1994) (49)
- Comparison of continuous and pulsed low dose rate brachytherapy: biological equivalence in vivo. (1994) (47)
- Survival of mouse testicular stem cells after gamma of neutron irradiation. (1980) (47)
- Volume effects in the irradiated canine spinal cord: do they exist when the probability of injury is low? (1998) (47)
- Comparison of treatment tolerance and outcomes in patients with cervical cancer treated with concurrent chemoradiotherapy in a prospective randomized trial or with standard treatment. (2008) (46)
- Dose Fractionation and Volume Effects in Normal Tissues and Tumors (1988) (46)
- A web-based search engine for triplex-forming oligonucleotide target sequences. (2006) (45)
- Tumor response, mucosal reactions and late effects after conventional and hyperfractionated radiotherapy. (1998) (45)
- The Limitations of Model-Based Experimental Design and Parameter Estimation in Sloppy Systems (2016) (45)
- Chronic radiation damage in the rat rectum: an analysis of the influences of fractionation, time and volume. (1994) (44)
- Failure definition-dependent differences in outcome following radiation for localized prostate cancer: can one size fit all? (2003) (44)
- Impact of adjuvant inhibition of vascular endothelial growth factor receptor tyrosine kinases on tumor growth delay and local tumor control after fractionated irradiation in human squamous cell carcinomas in nude mice. (2005) (44)
- Does heterogeneity of pimonidazole labelling correspond to the heterogeneity of radiation-response of FaDu human squamous cell carcinoma? (2005) (44)
- A dose-surviving fraction curve for mouse colonic mucosa. (1983) (44)
- Accelerated repopulation during fractionated irradiation of a murine ovarian carcinoma: downregulation of apoptosis as a possible mechanism. (1996) (43)
- The response of Chinese hamster ovary cells to fast neutron radiotherapy beams. III. Variation in biological effectiveness with position in the cell cycle. (1978) (43)
- Is the experience with CHART compatible with experimental data? A new model of repair kinetics and computer simulations. (1992) (43)
- Residual DNA double strand breaks in perfused but not in unperfused areas determine different radiosensitivity of tumours. (2011) (43)
- Cell density dependent plating efficiency affects outcome and interpretation of colony forming assays. (1996) (43)
- Flexure dose: the low-dose limit of effective fractionation. (1983) (43)
- Twice-daily fractionation schemes for advanced head and neck cancer. (1984) (42)
- The translational research chain: is it delivering the goods? (2001) (41)
- Use of the LQ model with large fraction sizes results in underestimation of isoeffect doses. (2013) (39)
- Cluster models of dose-volume effects. (2004) (39)
- A biochemical definition of cure after brachytherapy for prostate cancer. (2020) (38)
- Post-irradiation hyperamylasemia as a biological dosimeter. (1992) (37)
- Diurnal variations in the expression of radiation-induced apoptosis. (1998) (37)
- Effect of latency on calculated complication rates. (1986) (36)
- TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects (2017) (36)
- Radiation nephropathy in the rhesus monkey: morphometric analysis of glomerular and tubular alterations. (1995) (36)
- Dose-volume conundrum for response of prostate cancer to brachytherapy: summary dosimetric measures and their relationship to tumor control probability. (2004) (35)
- γH2AX assay in ex vivo irradiated tumour specimens: A novel method to determine tumour radiation sensitivity in patient-derived material. (2015) (35)
- Relative biological effectiveness (RBE) of 50 MV (Be) neutrons for acute and late skin injury. (1978) (35)
- Residual γH2AX foci predict local tumour control after radiotherapy. (2013) (35)
- Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice. (2014) (34)
- Prognostic Value of Radiobiological Hypoxia during Fractionated Irradiation for Local Tumor Control (2011) (34)
- Normalization of in vitro sensitivity testing of human tumor clonogenic cells. (1984) (33)
- Changes in TCD50 as a measure of clonogen doubling time in irradiated and unirradiated tumors. (1991) (33)
- Early fractionation methods and the origins of the NSD concept. (1988) (33)
- Time factors in breast carcinoma: influence of delay between external irradiation and brachytherapy. (1992) (32)
- A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non–Small-Cell Lung Cancer (2014) (32)
- Long-term adverse effects of radiation inhibition of restenosis: radiation injury to the aorta and branch arteries in a canine model. (1999) (32)
- Is the alpha/beta ratio for prostate cancer low? (2001) (31)
- Radiosensitization of Prostate Cancers In Vitro and In Vivo to Erbium-filtered Orthovoltage X-rays Using Actively Targeted Gold Nanoparticles (2017) (31)
- Defining recurrence after radiation for prostate cancer. (2005) (31)
- Early and late injuries in mouse rectum after fractionated X-ray and neutron irradiation. (1993) (30)
- Factors predictive of having four or more positive axillary lymph nodes in patients with positive sentinel lymph nodes: implications for selection of radiation fields. (2004) (30)
- Investigating the temporal effects of respiratory-gated and intensity-modulated radiotherapy treatment delivery on in vitro survival: an experimental and theoretical study. (2008) (30)
- On the Origin of Dose Fractionation Regimens in Radiotherapy (1992) (29)
- Repair rate in mouse lung after clinically relevant radiation doses per fraction. (1995) (29)
- Time course and outcome of central recurrence after radiation therapy for carcinoma of the cervix (2005) (28)
- New options in direct analysis of dose-response data. (1990) (28)
- The response of two human tumor xenografts to fractionated irradiation. The derivation of alpha/beta ratios from growth delay, tumor control, and in vitro cell survival assays. (1990) (28)
- Immunohistochemically Detected p53 Mutations in Epithelial Tumors and Results of Treatment with Chemotherapy and Radiotherapy A Treatment-Specific Overview of the Clinical Data (2002) (27)
- Direct analyses of in vivo colony survival after single and fractionated doses of radiation. (1991) (26)
- The challenge of p53 as prognostic and predictive factor in Hodgkin's or non-Hodgkin's lymphoma (2001) (25)
- Tumor radioresistance in clinical radiotherapy. (1982) (25)
- Recovery from sublethal damage during fractionated irradiation of human FaDu SCC. (2005) (25)
- The effect of cis-diamminedichloroplatinum(II) on radiation damage in mouse rectum after fractionated irradiation. (1989) (24)
- The clinical significance of ratios of radiobiological parameters. (1996) (24)
- Protection of mouse jejunal crypt cells by WR-2721 after small doses of radiation. (1986) (24)
- Mitigation and treatment of radiation-induced thoracic injury with a cyclooxygenase-2 inhibitor, celecoxib. (2013) (24)
- Does tumor control decrease by prolonging overall treatment time or interrupting treatment in laryngeal cancer? (1995) (23)
- Increasing external beam dose for T1-T2 prostate cancer: effect on risk groups. (2006) (23)
- Has the influence of treatment duration on local control of carcinoma of the cervix been defined? (1995) (21)
- A test for dose-modifying factors. (1978) (20)
- Overall treatment time and tumor control dose for head and neck tumors: the dog leg revisited. (1992) (20)
- Differentiation status of human squamous cell carcinoma xenografts does not appear to correlate with the repopulation capacity of clonogenic tumour cells during fractionated irradiation (2004) (20)
- Changes in the radiation sensitivity of mouse skin during fractionated and prolonged treatments. (1994) (20)
- Hyperfractionation: where do we stand? (1998) (20)
- Triplex‐forming oligonucleotides targeting c‐MYC potentiate the anti‐tumor activity of gemcitabine in a mouse model of human cancer (2014) (19)
- Effect of reduced EGFR function on the radiosensitivity and proliferative capacity of mouse jejunal crypt clonogens. (2004) (19)
- Repopulation of moderately well-differentiated and keratinizing GL human squamous cell carcinomas growing in nude mice. (2004) (19)
- Dose-response relationship for supraglottic laryngeal carcinoma. (1983) (18)
- Time-dose considerations for normal-tissue tolerance. (1989) (18)
- Impact of increased cell loss on the repopulation rate during fractionated irradiation in human FaDu squamous cell carcinoma growing in nude mice (2003) (18)
- Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines. (2010) (17)
- Tumor sensitizing effect by misonidazole in a clinically relevant radiation dose range. (1984) (17)
- Altered fractionation: radiobiological principles, clinical results, and potential for dose escalation. (1998) (17)
- Ex vivo γH2AX radiation sensitivity assay in prostate cancer: Inter-patient and intra-patient heterogeneity. (2017) (16)
- Radiation response of the monkey kidney following contralateral nephrectomy. (1994) (16)
- Repair factors for multifraction irradiations. (1984) (15)
- Core needle biopsies for determination of the microenvironment in individual tumours for longitudinal radiobiological studies. (2009) (15)
- Time factor for tonsillar carcinoma. (1995) (15)
- Chemotherapy and hormonal therapy in combination. (1988) (15)
- Is reseeding from the primary a plausible cause of node failure? (1993) (15)
- Comparison of mathematical models for radiation fractionation. (1976) (13)
- Incidence and latency of radiation reactions. (1989) (13)
- Year of treatment as independent predictor of relapse-free survival in patients with localized prostate cancer treated with definitive radiotherapy in the PSA era. (2004) (13)
- The true predictive value of the human tumor stem cell assay: does a workable assay select for treatment responders? (1984) (13)
- Response of fibrosarcoma cell subpopulations to small doses of radiation delivered in situ. (1983) (13)
- Biased methods for estimating local and distant failure rates in breast carcinoma and a “commonsense” approach (2001) (13)
- Machine segmentation of pelvic anatomy in MRI-assisted radiosurgery (MARS) for prostate cancer brachytherapy. (2020) (12)
- Optimal design of multifraction assays of colony survival in vivo. (1983) (12)
- Lower mean heart dose with deep inspiration breath hold-whole breast irradiation compared with brachytherapy-based accelerated partial breast irradiation for women with left-sided tumors. (2017) (12)
- Radiation for prostate cancer: use of biochemical failure as an endpoint following radiotherapy (2003) (11)
- The biochemical and clinical significance of the post-treatment PSA bounce for prostate cancer patients treated with external beam radiation therapy alone: A multi-institutional pooled analysis (2004) (11)
- Dose-response relationships for late radiation effects in the head and neck: regarding the analysis of the RTOG 8313 trial, Fu et al. IJROBP 32:577-588; 1995. (1996) (10)
- The relationship of acute to late skin injury in 2 and 5 fraction/week gamma-ray therapy. (1978) (9)
- Hypofractionation in retinoblastoma: an increased risk of retinopathy. (1993) (9)
- Chemosensitivities of human clonogenic breast tumor cells. (1986) (9)
- A morphometric analysis of glomerular and tubular alterations following fast-neutron irradiation of the pig and monkey kidney. (1998) (9)
- Impact of pre- and early per-treatment FDG-PET based dose-escalation on local tumour control in fractionated irradiated FaDu xenograft tumours. (2016) (9)
- Computational Modeling of Micrometastatic Breast Cancer Radiation Dose Response. (2016) (9)
- Changes in clonogen number and radiation sensitivity in mouse jejunal crypts after treatment with dimethylsulfoxide and retinoic acid. (1996) (8)
- Fractionation effect on radiation-induced growth retardation of tibia in rabbits and rats. (1998) (8)
- Predicting Radiosensitivity Using DNA End-Binding Complex Analysis (2004) (8)
- Risk Factors for Local Relapse and Inferior Disease‐free Survival After Breast‐conserving Management of Breast Cancer: Recursive Partitioning Analysis of 2161 Patients (2019) (8)
- Kinetics of recovery from sublethal radiation damage. (1989) (8)
- Effects of volume irradiated on the function of the canine ureter. (1998) (8)
- Articular cartilage scores in cranial cruciate ligament‐deficient dogs with or without bucket handle tears of the medial meniscus (2017) (8)
- Experimental Study of the Flow Field Inside a Whirling Annular Seal (1992) (7)
- p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade (2021) (7)
- A parametric method for estimation of dose-modifying factors: low-dose extrapolation limit. (1977) (7)
- Fractionation sensitivity and immunological status in radiation treated murine sarcomas. (1990) (7)
- Intensity modulated radiation therapy (IMRT) for post-hysterectomy pelvic radiation: selection of patients and planning target volume (PTV) (2002) (7)
- A 100-year Nordic perspective on the dose-time problem in radiobiology. (1995) (7)
- Proliferation kinetics of a murine fibrosarcoma during fractionated irradiation. (1988) (7)
- PSA after radiation for prostate cancer. (2004) (7)
- Induction of transforming growth factor alpha in irradiated mouse jejunum. (1998) (7)
- Mean flow and turbulence characteristics in whirling annular seals (1992) (6)
- In regard to Solomon et al.: EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. IJROBP 2003;55:713-723. (2003) (6)
- Local-regional control in breast cancer patients with a possible genetic predisposition. (2000) (6)
- 2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide. (2010) (6)
- Prognostic value of HIF-1α expression during fractionated irradiation (2012) (6)
- Dual radiobiological interpretations of retrospective clinical data: the time factor (2003) (5)
- Concurrent Chemoradiation in the Routine Management of Patients With Cervical Cancer: Does Marital Status Matter? (2009) (5)
- Are the results of the St Thomas' trial of post-mastectomy radiotherapy inconsistent with the predictions from the linear-quadratic model? (1989) (5)
- The probability of tumor cure: Response to comments by Dr. Yakovlev [2] (1993) (5)
- Retrospective investigation of the prognostic value of the β1 integrin expression in patients with head and neck squamous cell carcinoma receiving primary radio(chemo)therapy (2018) (5)
- Will identifying or targeting altered marker expression in response to cytotoxic therapy be of prognostic or therapeutic value? (2003) (5)
- The Proliferative Response of Mouse Jejunal Crypt Cells to Radiation-Induced Cell Depletion is not Mediated Exclusively by Transforming Growth Factor Alpha (2001) (5)
- Integration of Radiation Therapy and Systemic Therapy for Breast Cancer (2006) (4)
- Combined modality in advanced Hodgkin's disease. (1998) (4)
- Dr. H. Rodney Withers (1932 – 2015) (2015) (4)
- Comparison of the Flow Inside Whirling and Non-Whirling Smooth Annular Seals at 50% Eccentricity (2002) (4)
- In response to Drs. King and Fowler (2002) (4)
- Clinically-relevant pneumonitis is not increased in breast cancer patients treated with sequential paclitaxel and radiation (2003) (4)
- Phase Averaged Wall Shear Stress, Wall Pressure and Near Wall Velocity Field Measurements in a Whirling Annular Seal (1995) (4)
- Effect of dose per fraction on the division potential of lethally irradiated plateau-phase CHO cells exposed to isoeffective fractionation regimens. (1986) (4)
- Predictors of hormone response for patients with ER-unknown breast tumours. (1989) (4)
- Prognostic value of HIF-1 alpha expression during fractionated irradiation (2012) (4)
- Computer-aided segmentation on MRI for prostate radiotherapy, part II: Comparing human and computer observer populations and the influence of annotator variability on algorithm variability. (2021) (3)
- Predicting outcome after PSA failure in prostate cancer patients treated by radiation. Who needs salvage therapy (2004) (3)
- Computer-aided segmentation on MRI for prostate radiotherapy, part I: Quantifying human interobserver variability of the prostate and organs at risk and its impact on radiation dosimetry. (2021) (3)
- 5-FU-based adjuvant chemotherapy given after neoadjuvant chemoradiation and surgery for rectal cancer improves survival only among responders (2001) (3)
- RBE of 50 MV(Be) neutrons for acute and late skin injury (1977) (3)
- In response to Dr. Lee (2002) (3)
- The effect of proliferative status and clonogen content on the response of mouse jejunal crypts to split-dose irradiation. (1997) (3)
- Pulsed & continuous low-dose rate brachytherapy: Biological equivalence in vivo (1993) (3)
- Influence of fraction size on local control and complication rates in definitive radiotherapy for stage tz glottic cancer (1990) (3)
- Survival of human bone marrow cells after in vitro treatment with 12 anticancer drugs and implications for tumor drug sensitivity assays (1985) (3)
- Clinical outcomes and prognostic factors in 4839 patients treated with external radiotherapy for stage T1-T2 prostate cancer (2004) (3)
- Effect of continuous infusion of bleomycin on the time for completion of repair of sublethal radiation damage in mouse lip mucosa during fractionated irradiation. (1988) (3)
- Response of plateau-phase C3H 10T1/2 cells to radiation and concurrent administration of bleomycin. (1989) (3)
- Prospective Evaluation of Prostate and Organs at Risk Segmentation Software for MRI-based Prostate Radiation Therapy. (2022) (3)
- Chemoresistance is not a cause of the apparent failure of adjuvant chemotherapy in postmenopausal women. (1988) (2)
- A Biochemical Definition of Cure Following Brachytherapy for Prostate Cancer: A Multi-Institution International Study (2019) (2)
- Is Anemia a Cause of Radiation Treatment Failure in Patients with Squamous Carcinoma of the Cervix (2005) (2)
- A new model of proliferative response to fractionated irradiation. (1988) (2)
- Abstract 1661: TRIP12 as a mediator of human papillomavirus/p16-related radiation enhancement effects (2016) (2)
- In Memoriam: H. Rodney Withers (21 September 1932–25 February 2015) (2015) (2)
- The origins of translational radiation oncology - In memoriam H. Rodney Withers (21 September 1932-25 February 2015). (2015) (2)
- First scatter to off-axis points and the Clarkson method. (1973) (2)
- Mathematical Models of Dose and Cell Cycle Effects in Multifraction Radiotherapy (2017) (2)
- Early and late gastrointestinal complications following radiotherapy for carcinoma of the cervix. (1983) (2)
- Final Report of Radiation Therapy Oncology Group Protocol 9003: Provocative, but Limited Conclusions From Exploratory Analyses. (2015) (2)
- An Experimental Technique for Performing 3-D LDA Measurements Inside Whirling Annular Seals, (1994) (2)
- Turbulence Measurements of High Shear Flow Fields in a Turbomachine Seal Configuration (1993) (2)
- On the α/β ratio and oer for clonogenic tumor cells (1985) (2)
- PSA failure free survival following irradiation for stage T1–T2 prostate cancer patients: The results of an ASTRO sponsored pooled analysis (1998) (2)
- Factors associated with breast recurrence in young females treated with breast conservation therapy: how young is young? (2003) (1)
- Influence of total treatment time on local control rates after radiotherapy for breast cancer (1991) (1)
- Prognostic risk group stratification for clinical and biochemical failure after external beam radiation of localized prostate cancer (2004) (1)
- Mathematical Models in Cancer Research (1990) (1)
- The clonogenic growth of advanced breast tumour lesions adds no value to that of established clinical prognosticators for survival. (1993) (1)
- Responses of human bone marrow progenitor cells to fluoro-ara-AMP, homoharringtonine, and elliptinium (2004) (1)
- Quantitative high-throughput measurement of gene expression with sub-zeptomole sensitivity by capillary electrophoresis. (2005) (1)
- Definitions of biochemical failure that best predict clinical failure in prostate cancer patients treated with external beam radiation alone- a multi-institutional pooled analysis (2003) (1)
- Higher Mean Heart Dose With Brachytherapy Based Accelerated Partial-Breast Irradiation Compared to External Beam Whole-Breast Irradiation With Breath-Hold in Women With Left-Sided Tumors (2015) (1)
- What can be expected from elective regional radiotherapy? (1999) (1)
- Splenic radiation during pancreatic cancer radiotherapy: Are we throwing the baby out with the bath water? (2016) (1)
- The Withers archive: Online availability of rod Wither's data. (2016) (1)
- Radiosensitization of Prostate Cancers In Vitro and In Vivo to Erbium-filtered Orthovoltage X-rays Using Actively Targeted Gold Nanoparticles (2017) (1)
- Investigating the Effects of Respiratory Gated IMRT Treatment Delivery on Survival (2005) (1)
- Locoregional R ecurrence P atterns A fter M astectomy a nd Doxorubicin-Base d C hemotherapy: I mplications f or Postoperative I rradiation (2000) (1)
- Long-term toxicity of radiation inhibition of restenosis: Injury to the aorta and branch arteries in a canine model (1998) (1)
- Sample-size calculation for preclinical dose-response experiments using heterogeneous tumour models. (2021) (1)
- Possible Failure of the LQ Model With Large Fraction Sizes (2013) (1)
- Benchmarking Automatic Segmentation Algorithms Against Human Interobserver Variability of Prostate and Organs at Risk Delineation on Prostate MRI. (2021) (1)
- A model simulating photon transport in a finite medium (1971) (1)
- C o r r elation o f S moking H istory a nd O ther P atient Characteristics W ith M ajor C omplications o f P elvic Radiation T herapy f or C ervical C ancer (2002) (0)
- Progression of radiation induced fibrosis after breast conserving treatment of mammary cancer (1991) (0)
- Differences in outcome of young breast cancer patients according to BRCA1 mutation status. (2009) (0)
- A new method for computer generation of dose distributions from external x- and gamma-ray sources. (1973) (0)
- Time Factor for Radiotherapy of Prostate Cancer: Retrospective Analysis of Biochemical Failure in 4839 Men Treated between 1987 and 1995 (2010) (0)
- Influence of fractionated irradiations on the growth kinetics of a murine fibrosarcoma (1986) (0)
- 834 The influence of cell density dependent plating efficiency on clonogenic assays (1995) (0)
- 291 BREAST CANCER: PERSISTING RISKS IN PRE-MENOPAUSAL WOMEN AFTER BREAST CONSERVING SURGERY RADIOTHERAPY, +/-SYSTEMIC THERAPIES (2012) (0)
- Frequency o f F irst M etastatic E vents i n B reast C ancer: Implications f or S equencing o f S ystemic and L ocal-Regional T reatment (1999) (0)
- Meta-analytic comparison of randomized and nonrandomized studies of breast cancer surgery: Edwards JP, Kelly EJ, Lin Y, et al (Univ of Calgary, Alberta, Canada) Can J Surg 55:155-162, 2012§ (2012) (0)
- Wall Shear Stress, Wall Pressure and Near Wall Velocity Field Relationships in a Whirling Annular Seal (1996) (0)
- A general purpose method for computer generation of isodose contours from external X-ray sources with applications to treatment planning (1972) (0)
- Rod Withers' Data are Available Online. (2017) (0)
- The dose-volume conundrum in low dose-rate prostate implants: is it better to moderately underdose a large volume, or grossly underdose a small volume (2002) (0)
- 513 POSTER Characteristic and outcome of young breast cancer patients with and without BRCA1 mutations (2007) (0)
- Validation of biochemical definition of cure after low-dose rate prostate brachytherapy. (2020) (0)
- Eccentricity effects upon the flow field inside a whirling annular seal (1995) (0)
- Dose-volume relationships of radiation injury to canine lung (2000) (0)
- 18 oral: Pretreatment F-Miso Hypoxic Volume is Prognostic for Local Control after Single Dose Irradiation in FADU HSCC (2010) (0)
- Response to Letter of C. W. Song, F. M. Uckun, S. H. Levitt and T. H. Kim (1994) (0)
- 2006 Influence of overall treatment time on local control of breast cancer after radiotherapy alone (1999) (0)
- SU‐FF‐T‐427: The Significance of Higher Dose Rates for Stereotactic Body Radiation Therapy (2006) (0)
- Differences in outcome of young breast cancer patients according to BRCA1 mutation status (2008) (0)
- Role of culture conditions and exposure duration in determining sensitivity of human bone marrow progenitor cells to methotrexate (2004) (0)
- SP-0002 WHEN IS HYPOFRACTIONATION MANDATORY: THE RADIOBIOLOGIST'S AND CLINICAL POINT OF VIEW? (2012) (0)
- new mo rative response frac ir (1988) (0)
- PO-0851: LQ model with large fraction sizes leads to underestimation of isoeffect doses (2014) (0)
- Comparing cell survival estimated from in vivo and in vitro data: beware in vivo heterogeneity. (1994) (0)
- P06 15 SP – INDIVIDUAL VARIATION IN THE RADIOSENSITIVITY OF HUMAN SKIN (1991) (0)
- The Withers Archive: online availability of H. Rodney Withers’ data (2016) (0)
- Biophysical Models in Radiation Oncology by L. Cohen (1984) (0)
- Is The Phoenix Criterion Of Biochemical Failure (BF) In Men Treated With Low-Dose Rate Prostate Brachytherapy Appropriate? (2020) (0)
- The correlation between tumor volume and clonogen number: evidence for a linear relationship in advanced squamous cell carcinoma of the head and neck (1994) (0)
- A Biochemical Definition of Cure Following Brachytherapy of Prostate Cancer (2019) (0)
- The influence of dose and time on the cure of larynx tumors. (1992) (0)
- Persisting risk after BCT in N+ and N− patients – a single institution analysis from 1485 patients (2008) (0)
- 64: Identification of the Bladder Dose and Volume Constraints to Control Late Urinary Toxicity After External Beam Radiotherapy for Prostate Cancer (2006) (0)
- Time, Dose and Fractionation in the Radiation Therapy of Cancer, Volume 22, Frontiers in Radiation Therapy and Oncology (1989) (0)
- EXPERIENCE WITH THE CONCOMITANT BOOST REGIMEN AT UT M.D. ANDERSON CANCER CENTER (1991) (0)
- 2007 : Prognostic Groups in Node-Negative and Node-Positive Breast Cancer Patients Treated With Breast Conservation Surgery and Adjuvant Radiotherapy: a Recursive Partitioning Analysis (RPA) Based on 1347 Patients (2006) (0)
- 80 Radiotherapy of organ-confined prostate cancer: Biochemical failure definitions and risk groups (2006) (0)
- Megavoltage Radiotherapy 1937–1987 (1989) (0)
- Paclitaxel-Based Chemotherapy and Radiotherapy in Breast Cancer Patients (2004) (0)
- 905 ORAL Risk analysis in breast cancer patients younger than 45 years: which risk parameters gain in importance after breast conserving surgery (BCS), systemic therapy (ST) and radiation therapy (RT)? (2007) (0)
- In Reply to Drs. Pickles and Williams (2007) (0)
- Proton Therapy for Localized Prostate Cancer: Long-Term Clinical Outcomes at a Comprehensive Cancer Center (2022) (0)
- Recursive partitioning analysis in breast cancer patients treated by adjuvant whole breast radiotherapy followed by external beam boost or brachytherapy boost: prognostic groups in 1485 patients (2006) (0)
- Modality sequence and prophylactic cranial irradiation (PCI) are most significant in recursive partitioning analysis (RPA) of patients with limited small cell lung cancer (SCLC) treated with combined modality therapy (1998) (0)
- 108 Tumor microenvironment and outcome of fractionated irradiation in different human squamous cell carcinomas (HSCC) growing in nude mice (2006) (0)
- [The meta-analysis of clinical studies on chemotherapy alone compared to a combination of chemotherapy plus radiotherapy in the treatment of Hodgkin's disease]. (1998) (0)
- Influence on node control of dose, time and node diameter in node positive head and neck carcinoma : Further analysis of the institut curie series (1990) (0)
- Compressible and incompressible fluid seals: Influence on rotordynamic response and stability (1992) (0)
- Moist desquamation and telangiectasia in patients treated by postmastectomy irradiation. (1991) (0)
- Breast Tumor Location and the Impact of Nodal Status on Local Recurrence (LR) and Disease Free Survival (DFS) (2010) (0)
- Radiation Therapy for Clinically Localized Prostate Cancer (2016) (0)
- A new predictor for response to endocrine treatment (1987) (0)
- Ablative Radiation Therapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma (2015) (0)
- 348 What Have We Learned From Recursive Partitioning Analyses in Breast Cancer Patients? a Single Institution Report On More Than 2000 Patients (2012) (0)
- 0217 Differences in outcome of young breast cancer patients according to BRCA1 mutation status (2009) (0)
- Corrigendum to “HPV16 DNA status is a strong prognosticator of loco-regional control after postoperative radiochemotherapy of locally advanced oropharyngeal carcinoma: Results from a multicentre explorative study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG)” [Radiother. Oncol. (2015) (0)
- Absorbed dose from first scatter to off-axis points and the accuracy of the Clarkson method (1974) (0)
- Nodal Status and Tumor Location -- An Unorthodox Relationship in Breast Cancer Patients (2012) (0)
- A comparison of acute and late p.adiation responses (1981) (0)
- Outcomes after PD-103 versus I-125 for Low Dose Rate Prostate Brachytherapy Monotherapy: An International, Multi-Institutional Study. (2023) (0)
- 115 First Report of Real-time Tumor Tracking in the Treatment of Pancreatic Cancer using the Calypso System (2009) (0)
- A QUANTUM MECHANICAL CALCULATION OF THE HELIUM-HELIUM INTERACTION POTENTIAL (1970) (0)
- Prognostic factors identified in the long term survivors with limited small cell lung cancer (2008) (0)
- Assessing the Impact of Technological Advancement on Outcome for Patients With Unresectable Locally Advanced Non-Small Cell Lung Cancer (NSCLC) Receiving Concomitant Chemoradiotherapy (2007) (0)
- Response to DRS, Huang, Lin, and Schmidt-Ullrich (1995) (0)
- 1050 Influence of volume on intraoperatively irradiated canine ureters (1995) (0)
- 25 Repopulation in human squamous cell carcinoma FaDu: possible impact of the impairment of recovery from sublethal damage repair (2003) (0)
- A Case-Control Study of Cluster Size as Predictor of Rectal Bleeding in T1-T2 Prostate Cancer Patients Treated by IMRT (2005) (0)
- 1049 Dose volume relationships for intraoperatively irradiated saphenous nerve (1995) (0)
- The effect of misonidazole and fractionated low doses of radiation on selected tumor subpopulations in vivo. Abstr. (1982) (0)
- SU‐FF‐T‐270: Investigating the Temporal Effects of Respiratory Gated IMRT Treatment Delivery On in Vitro Survival: A Theoretical and Experimental Study (2007) (0)
- Which Risk Parameters Gain in Importance after Breast Conserving Surgery (BCS), Systemic Therapy (ST) and Radiation Therapy (RT)? An Analysis from 2,162 Patients (2009) (0)
- SP-0003 WHEN IS HYPOFRACTIONATION MANDATORY: THE RADIOBIOLOGIST'S AND CLINICAL POINT OF VIEW? (2012) (0)
- 502 Repopulation of the moderately well differentiated GL human squamous cell carcinoma growing in nude mice (2003) (0)
- Comparison of pathological risk factors for postmastectomy local-regional recurrence after neoadjuvant versus adjuvant chemotherapy for patients not treated with radiation (2001) (0)
- OC-131 BREAST CANCER: EXTERNAL BEAM RADIOTHERAPY AND INTERSTITIAL BOOST APPLICATION – AN ANALYSIS OF 1065 PATIENTS. (2012) (0)
- PO-0962: Experimental evaluation of a novel application of the gammaH2AX assay to predict tumour radiation sensitivity (2014) (0)
- The Withers Archive: Online Availability of H. Rodney Withers' Data (2016) (0)
- In response to Drs. Schultz and Kagan (2004) (0)
- [Multivariate analysis--do we understand what we are doing?]. (1999) (0)
- 78: Are the Risk Groups Used for External Beam Treatment of Prostate Cancer Appropriate for Ldr Brachytherapy? (2021) (0)
- 89 A Biochemical Definition of Cure Following Brachytherapy of Prostate Cancer (2019) (0)
- [Multivariate analysis--do we understand what we are doing?]. (1999) (0)
- Phase-Averaged Wall Shear Stress, Wall Pressure, and Near-Wall Velocity Field Measurements in a Whirling Annular Seal (1996) (0)
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