Hsin‐hsiung Tai
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Hsin‐hsiung Taibiology Degrees
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Biochemistry
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Biology
Hsin‐hsiung Tai's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry National Taiwan University
Why Is Hsin‐hsiung Tai Influential?
(Suggest an Edit or Addition)Hsin‐hsiung Tai's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. (1974) (508)
- Prostaglandin catabolizing enzymes. (2002) (341)
- 15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer* (2005) (312)
- 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. (2004) (252)
- Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration (2015) (206)
- 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer. (2006) (200)
- Oxidoreductases in Lipoxin A4 Metabolic Inactivation (2000) (169)
- Most efficient cocaine hydrolase designed by virtual screening of transition states. (2008) (165)
- Computational redesign of human butyrylcholinesterase for anticocaine medication. (2005) (161)
- NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. (2004) (157)
- Immunohistochemical localization, messenger ribonucleic acid abundance, and activity of 15-hydroxyprostaglandin dehydrogenase in placenta and fetal membranes during term and preterm labor. (1994) (145)
- Metabolism of Prostaglandin Glycerol Esters and Prostaglandin Ethanolamides in Vitro and in Vivo * (2001) (138)
- 15-Hydroxyprostaglandin dehydrogenase. (1995) (133)
- Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia. (1986) (133)
- NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions. (2006) (124)
- Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester. (1988) (114)
- Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA. (1998) (112)
- Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution. (2015) (112)
- Leukotriene B4 Release and Polymorphonuclear Cell Infiltration in Spinal Cord Injury (1990) (110)
- 15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors (2009) (104)
- Thromboxanes: synthase and receptors. (1998) (103)
- Cloning and sequence analysis of the cDNA for human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. (1990) (96)
- On the inhibitory potency of imidazole and its derivatives on thromboxane synthetase. (1978) (95)
- Formation of Prostaglandins E2 and D2 via the Isoprostane Pathway (2003) (92)
- Pioglitazone and Rosiglitazone Decrease Prostaglandin E2 in Non–Small-Cell Lung Cancer Cells by Up-Regulating 15-Hydroxyprostaglandin Dehydrogenase (2007) (90)
- Site-directed mutagenesis of the conserved tyrosine 151 of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase yields a catalytically inactive enzyme. (1991) (90)
- Design, Preparation, and Characterization of High-Activity Mutants of Human Butyrylcholinesterase Specific for Detoxification of Cocaine (2011) (84)
- Biosynthesis of prostaglandins in rabbit kidney medulla. Properties of prostaglandin synthase. (1976) (82)
- Squalene epoxidase of rat liver. (1972) (81)
- Immunocytochemical distribution and localization of 15-hydroxyprostaglandin dehydrogenase in human fetal membranes, decidua, and placenta. (1990) (78)
- 15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Gastric Cancer (2009) (78)
- 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer. (2007) (76)
- Release of arachidonate from diglyceride in human platelets requires the sequential action of a diglyceride lipase and a monoglyceride lipase. (1981) (76)
- Urinary Prostaglandin F2α Is Generated from the Isoprostane Pathway and Not the Cyclooxygenase in Humans* (2007) (75)
- Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha. (2006) (74)
- Phorbol ester, 1,2-diacylglycerol, and collagen induce inhibition of arachidonic acid incorporation into phospholipids in human platelets. (1989) (71)
- Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer. (2007) (64)
- Prostaglandin catabolic enzymes as tumor suppressors (2011) (64)
- Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets. (1985) (64)
- Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells. (2006) (60)
- Molecular dynamics simulation of cocaine binding with human butyrylcholinesterase and its mutants. (2005) (59)
- Gossypol, a potent inhibitor of arachidonate 5- and 12-lipoxygenases. (1985) (59)
- Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation. (2006) (59)
- Development of radioimmunoassay for thromboxane B2. (1978) (59)
- Free-energy perturbation simulation on transition states and redesign of butyrylcholinesterase. (2009) (57)
- Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells. (1996) (55)
- Enzymatic synthesis of (15s)-[15-3h]prostaglandins and their use in the development of a simple and sensitive assay for 15-hydroxyprostaglandin dehydrogenase. (1976) (55)
- Activation of thromboxane A(2) receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells. (2009) (54)
- Activation of Thromboxane A2 Receptor (TP) Increases the Expression of Monocyte Chemoattractant Protein -1 (MCP-1)/Chemokine (C-C motif) Ligand 2 (CCL2) and Recruits Macrophages to Promote Invasion of Lung Cancer Cells (2013) (52)
- Differential changes in 15-hydroxyprostaglandin dehydrogenase and prostaglandin H synthase (types I and II) in human pregnant myometrium. (2002) (51)
- Arachidonic Acid and Its Metabolites in Cerebral Ischemia a (1989) (51)
- Localization of 15-hydroxy prostaglandin dehydrogenase in human fetal membranes, decidua, and placenta during pregnancy. (1992) (50)
- Abnormal platelet response to thromboxane A2. (1981) (50)
- Characterization of recombinant human CXCR4 in insect cells: role of extracellular domains and N-glycosylation in ligand binding. (1999) (50)
- Stimulations of arachidonate release and inositol-1,4,5-triphosphate formation are mediated by distinct G-proteins in human platelets. (1987) (49)
- Induction of NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase expression by androgens in human prostate cancer cells. (2000) (49)
- Novel human mPGES-1 inhibitors identified through structure-based virtual screening. (2011) (49)
- NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase Regulates Levels of Bioactive Lipids in Non–Small Cell Lung Cancer (2008) (49)
- Bacterial expression and site-directed mutagenesis of two critical residues (tyrosine-151 and lysine-155) of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. (1994) (49)
- Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice. (2008) (47)
- Synthesis and biological evaluation of novel thiazolidinedione analogues as 15-hydroxyprostaglandin dehydrogenase inhibitors. (2011) (47)
- Coordinate regulation of prostaglandin metabolism for induction of parturition in mice. (2002) (46)
- Thromboxane receptor alpha mediates tumor growth and angiogenesis via induction of vascular endothelial growth factor expression in human lung cancer cells. (2010) (45)
- Thiazolidinediones as a novel class of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors. (2002) (45)
- Plasma secretin and gastrin responses to a meat meal and duodenal acidification in dogs. (1976) (44)
- Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells. (2004) (44)
- Polyamine and prostaglandin markers in focal cerebral ischemia. (1985) (44)
- Rapid extraction of secretin from plasma by XAD-2 resin and its application in the radioimmunoassay of secretin. (1978) (43)
- Understanding microscopic binding of human microsomal prostaglandin E synthase-1 (mPGES-1) trimer with substrate PGH2 and cofactor GSH: insights from computational alanine scanning and site-directed mutagenesis. (2010) (43)
- Immunoaffinity purification and characterization of thromboxane synthase from porcine lung. (1986) (41)
- Simultaneous radioimmunoassay of Secretin and gastrin. (1976) (41)
- Prostaglandin 9-ketoreductase/type II 15-hydroxyprostaglandin dehydrogenase is not a prostaglandin specific enzyme. (1981) (39)
- Plasma secretin concentrations in fasting and postprandial state in man (1978) (39)
- Synthesis and SAR of thiazolidinedione derivatives as 15-PGDH inhibitors. (2010) (39)
- Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase. (2008) (38)
- Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents. (2002) (38)
- Diglyceride/monoglyceride lipases pathway is not essential for arachidonate release in thrombin-activated human platelets. (1983) (38)
- Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung. (1998) (38)
- The Escherichia coli-derived Fab fragment of the IgM/kappa antibody IN-1 recognizes and neutralizes myelin-associated inhibitors of neurite growth. (1996) (37)
- Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells. (1995) (36)
- Preparation and in vivo characterization of a cocaine hydrolase engineered from human butyrylcholinesterase for metabolizing cocaine. (2013) (35)
- Interleukin-1 beta and dexamethasone regulate gene expression of prostaglandin H synthase-2 via the NF-kB pathway in human amnion derived WISH cells. (1998) (35)
- Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding. (2000) (35)
- Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester. (1991) (35)
- Preparation of 125I-labeled secretin of high specific radioactivity. (1975) (34)
- Radioimmunoassay of motilin. Validation and studies on the relationship between plasma motilin and interdigestive myoelectric activity of the duodenum of dog. (1978) (34)
- Histone deacetylase inhibitors and transforming growth factor-β induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells (2006) (34)
- Structural and functional characterization of human microsomal prostaglandin E synthase-1 by computational modeling and site-directed mutagenesis. (2006) (33)
- NAD+-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney. I. Purification and partial characterization. (1980) (33)
- Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene. (1997) (33)
- Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. (2004) (31)
- Thromboxane A2 receptor‐mediated release of matrix metalloproteinase‐1 (MMP‐1) induces expression of monocyte chemoattractant protein‐1 (MCP‐1) by activation of protease‐activated receptor 2 (PAR2) in A549 human lung adenocarcinoma cells (2014) (31)
- Prostaglandin E2 alterations during sepsis are partially mediated by endotoxin-induced inhibition of prostaglandin 15-hydroxydehydrogenase. (1997) (30)
- Prostaglandin 9-ketoreductase and type II 15-hydroxyprostaglandin dehydrogenase from swine kidney are alternate activities of a single enzyme protein. (1981) (30)
- Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). (2011) (29)
- Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2. (2006) (29)
- Calcium stimulation of a novel 12-lipoxygenase from rat basophilic leukemia (RBL-1) cells. (1984) (29)
- Monoclonal antibodies to thromboxane synthase from porcine lung. Production and application to development of a tandem immunoradiometric assay. (1986) (29)
- Hypoxia stimulates prostacyclin generation by dog lung in vitro. (1982) (28)
- Activation of thromboxane receptor alpha induces expression of cyclooxygenase-2 through multiple signaling pathways in A549 human lung adenocarcinoma cells. (2007) (28)
- Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells. (1991) (27)
- Phosphorylation and desensitization of the human thromboxane receptor-alpha by G protein-coupled receptor kinases. (2001) (26)
- Development of radioimmunoassay for motilin. (1978) (26)
- 12-L-hydroxy-5,8,10-heptadecatrienoic acid (HHT) is an excellent substrate for NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. (1985) (25)
- Induction of fatty acid cyclooxygenase in rat aortic smooth muscle cells by estradiol. (1983) (25)
- The role of N-glycosylation of human thromboxane A2 receptor in ligand binding. (1998) (25)
- Threonine 188 is critical for interaction with NAD+ in human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. (1999) (24)
- Differential production of prostaglandin E(2) in male and female mice subjected to thermal injury contributes to the gender difference in immune function: possible role for 15-hydroxyprostaglandin dehydrogenase. (2000) (24)
- Elevated thromboxane B2 levels in periodontal disease. (1981) (24)
- Agonist-induced lipoxin A4 generation: Detection by a novel lipoxin A4-ELISA (1993) (24)
- Radioimmunoassay of vasoactive intestinal polypeptide. (1979) (24)
- Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. (2003) (23)
- 15-Hydroxyprostaglandin dehydrogenase can be induced by dexamethasone and other glucocorticoids at the therapeutic level in A549 human lung adenocarcinoma cells. (2005) (23)
- Hypoxia provokes leukotriene-dependent neutrophil sequestration in perfused rabbit hearts. (1987) (23)
- Expression of two different forms of cDNA for thromboxane synthase in insect cells and site-directed mutagenesis of a critical cysteine residue. (1993) (23)
- Purification of thromboxane synthetase and evidence of two distinct mechanisms for the formation of 12-L-hydroxy-5,8,10-heptadecatrienoic acid by porcine lung microsomes. (1981) (23)
- 9-Hydroxyprostaglandin dehydrogenase from rat kidney. Purification to homogeneity and partial characterization. (1980) (23)
- Burn injury with infection alters prostaglandin E2 synthesis and metabolism. (1998) (23)
- Transformation of arachidonate into 6-oxoprostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 by sheep lung microsomal fraction. (1978) (23)
- 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. (2009) (22)
- Phenylalanine 138 in the second intracellular loop of human thromboxane receptor is critical for receptor-G-protein coupling. (1999) (22)
- Selective inhibition of leukotriene B4 biosynthesis in rat pulmonary alveolar macrophages by dietary selenium deficiency. (1985) (22)
- Anti-inflammatory pharmacology and mechanism of the orally active capsaicin analogs, NE-19550 and NE-28345 (1990) (22)
- Site-directed mutagenesis of the conserved serine 138 of human placental NAD+-dependent 15-hydroxyprostaglandin dehydrogenase to an alanine results in an inactive enzyme. (1996) (22)
- Cloning and expression of the cDNA for mouse NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. (1996) (22)
- Serine 331 is the major site of receptor phosphorylation induced by agents that activate protein kinase G in HEK 293 cells overexpressing thromboxane receptor alpha. (2001) (22)
- Mechanism of prostaglandin biosynthesis in rabbit kidney medulla. A rate-limiting step and the differential stimulatory actions of L-adrenaline and glutathione. (1976) (21)
- Stimulation of prostaglandin E2 synthesis by interleukin-1beta is amplified by interferons but inhibited by interleukin-4 in human amnion-derived WISH cells. (1996) (21)
- Monoglyceride and diglyceride lipases from human platelet microsomes. (1988) (20)
- Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. (2009) (20)
- Stimulation of 12-lipoxygenase activity in rat platelets by 17β-estradiol (1982) (20)
- Photoaffinity labeling of human placental NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase with [alpha-32P]2N3NAD+. Identification of a peptide in the adenine ring binding domain. (1993) (19)
- Delayed elevation of platelet activating factor in ischemic hippocampus (1995) (19)
- Stimulation of cyclic nucleotide phosphodiesterase by products of phosphatidylinositol metabolism catalyzed by phospholipase A2. (1982) (19)
- A radioimmunoassay for 6-ketoprostaglandin E1. (1982) (19)
- 15‐hydroxyprostaglandin dehydrogenase suppresses K‐RasV12‐dependent tumor formation in Nu/Nu mice (2008) (19)
- Radioimmunological assay of prostacyclin synthetase activity. (1980) (19)
- Selective inhibition of thromboxane synthetase by pyridine and its derivatives. (1980) (19)
- Monoclonal antibodies that inhibit the enzyme activity of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. (1990) (18)
- Radioimmunoassay of motilin (1978) (18)
- A simple and sensitive assay for 9-hydroxyprostaglandin dehydrogenase. (1977) (18)
- Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells. (2012) (18)
- Glycogen Synthase Kinase-3 Phosphorylation, T-Cell Factor Signaling Activation, and Cell Morphology Change following Stimulation of Thromboxane Receptor α (2006) (17)
- Regulation of prostaglandin metabolism: activation of 15-hydroxyprostaglandin dehydrogenase by chlorpromazine and imipramine related drugs. (1976) (17)
- Oxidoreductases in Lipoxin A4 Metabolic Inactivation. A Novel Role for 15-oxoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in Inflammation (2000) (17)
- Restoration of leukotriene B(4)-12-hydroxydehydrogenase/15- oxo-prostaglandin 13-reductase (LTBDH/PGR) expression inhibits lung cancer growth in vitro and in vivo. (2010) (17)
- Altered hepatic eicosanoid concentrations in rats treated with the peroxisome proliferators ciprofibrate and perfluorodecanoic acid (2009) (16)
- High-sensitivity radioimmunoassay screening method for fentanyl. (1986) (16)
- Intramolecular ADP-ribose transfer reactions and calcium signalling. Potential role of 2'-phospho-cyclic ADP-ribose in oxidative stress. (1997) (15)
- Cysteine 182 is essential for enzymatic activity of human placental NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase. (1996) (15)
- A facile synthesis of an aldehydic analog of platelet activating factor and its use in the production of specific antibodies. (1990) (15)
- Cloning and expression of the cDNA for rat NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. (1997) (15)
- The porcine thromboxane synthase-encoding cDNA: sequence, mRNA expression and enzyme production in Sf9 insect cells. (1994) (15)
- Metabolism of prostaglandins in spontaneously hypertensive rats: NAD"-dependent 15-hydroxyprostaglandin dehydrogenase activity is decreased in kidney and increased in lung. (1979) (14)
- Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells. (2000) (14)
- Interleukin-4 up-regulates 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in human lung cancer cells. (2010) (14)
- Observations on plasma secretion levels by radioimmunoassay in response to duodenal acidification and to a meat meal in humans (1976) (14)
- Impairment of secretin release in celiac sprue (1978) (14)
- Characterization of two enzyme proteins catalyzing NADP+/NADPH-dependent oxidoreduction of prostaglandins at C-9 and C-15 from swine kidney. (1982) (14)
- Non-isotopic immunoassay drug tests in racing horses: a review of their application to pre- and post-race testing, drug quantitation, and human drug testing. (1988) (13)
- Group B Streptococcus Promotes Oxygen Radical-Dependent Thromboxane Accumulation in Young Piglets (1990) (13)
- Prostaglandin E2 receptor EP3alpha subtype: the role of N-glycosylation in ligand binding as revealed by site-directed mutagenesis. (1998) (13)
- Morphine and etorphine: XIV. Detection by ELISA in equine urine. (1991) (13)
- Cigarette smoking stimulates lipoxygenase but not cyclooxygenase pathway in platelets. (1983) (13)
- Inactivation of pulmonary NAD+-dependent 15-hydroxyprostaglandin dehydrogenase by acrolein. (1985) (12)
- An improved method of radioiodination with chloramine T. (1994) (12)
- Inhibition of thromboxane synthesis and platelet aggregation by pyridine and its derivatives. (1980) (12)
- Purification and characterization of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase from porcine kidney. (1990) (12)
- Selective inhibition of 5-lipoxygenase pathway in rat pulmonary alveolar macrophages by cigarette smoking. (1987) (12)
- Studies on the thromboxane synthesizing system in human platelet microsomes. (1978) (12)
- Monoclonal anti-idiotypic antibodies to platelet activating factor (PAF) and their interaction with PAF receptors. (1991) (11)
- Synthesis of [5,6-3H]arachidonic acid and its use in development of a sensitive assay for prostacyclin synthetase. (1980) (11)
- Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase. (2005) (11)
- Cyclic AMP response element mediates dexamethasone induced suppression of prostaglandin H synthase-2 gene expression in human amnion derived WISH cells. (1999) (11)
- NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase: immunochemical characterization of the lung enzyme from pregnant rabbits. (1990) (11)
- C-Terminal region of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase is involved in the interaction with prostaglandin substrates. (2001) (11)
- Activation of extracellular signal-regulated kinase by 12-hydroxyheptadecatrienoic acid in prostate cancer PC3 cells. (2007) (11)
- Changes in prostacyclin and thromboxane biosynthesis and their catabolic enzyme activity in kidneys of aging rats. (1984) (10)
- Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. (2006) (10)
- Threonine 11 of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase may interact with NAD(+) during catalysis. (2002) (10)
- Agents that elevate cyclic AMP induce receptor phosphorylation primarily at serine 331 in HEK 293 cells overexpressing human thromboxane receptor alpha. (2002) (9)
- Identification of metabolites of azaperone in horse urine. (1996) (9)
- Increase in thromboxane B2 and decrease in prostaglandin E2 and 6-keto-prostaglandin F1 alpha release into rat bronchoalveolar fluid as a consequence of cigarette smoking. (1987) (9)
- NAD+-dependent 15-hgydroxyprostaglandin dehydrogenase from porcine kidney. II. Kinetic studies. (1980) (9)
- Changes in arachidonate metabolism in aortas and platelets in aging rats. (1983) (9)
- 14-3-3ζ interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase (2006) (9)
- Pulmonary NAD+-linked 15-hydroxyprostaglandin dehydrogenase activity is decreased by cigarette smoking. (1984) (9)
- Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation. (2005) (9)
- Purification of NADP+/NADPH-dependent 15-hydroxyprostaglandin dehydrogenase and prostaglandin 9-ketoreductase from porcine kidney. (1982) (9)
- Alteration of platelet activating factor (PAF) metabolism in rat pulmonary alveolar macrophages and plasma by cigarette smoking. (1992) (9)
- Induction of a decrease in renal NAD+-dependent 15-hydroxyprostaglandin dehydrogenase activity by estradiol in rats. (1985) (9)
- Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets? (1988) (8)
- Effects of testosterone on the metabolism of arachidonic acid by aortas and platelets in rats. (1982) (8)
- Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses. (1989) (8)
- Alterations of arachidonate metabolism in cardiovascular system by cigarette smoking. (1990) (8)
- Cigarette smoke-induced alterations in the release of arachidonate metabolites by pulmonary alveolar macrophage from selenium-fed and selenium-deficient rats. (1986) (7)
- Structure and function of prostanoid receptors as revealed by site-directed mutagenesis. (1997) (7)
- Serine 331 is major site of phosphorylation and desensitization induced by protein kinase C in thromboxane receptor alpha. (2002) (7)
- Enzyme immunoassay of two nicergoline metabolites, 10 alpha-methoxy-9, 10-dihydrolysergol (MDL) and 1-methyl-10 alpha-methoxy-9, 10-dihydrolysergol (MMDL). (1996) (7)
- Phorbol ester induces inhibition of arachidonate incorporation into phospholipids in human neutrophils. (1990) (7)
- Resolution into two different forms and study of the properties of phosphatidylinositol-specific phospholipase C from human platelet cytosol. (1982) (7)
- Age-dependent mechanism in guinea pig bronchoconstriction induced by exsanguination. (1995) (7)
- Immunoassay detection of drugs in racing horses. XI. ELISA and RIA detection of fentanyl, alfentanil, sufentanil and carfentanil in equine blood and urine. (1989) (6)
- Streptococcus pneumoniae-induced alterations in levels of circulating thromboxane and prostacyclin: dissociation from granulocytopenia, thrombocytopenia, and pulmonary leukostasis. (1986) (6)
- A radioimmunoassay for human glucose phosphate isomerase: measurement of immunoreactive enzyme from genetic variants. (1980) (6)
- Roles of the vagus in endogenous release of secretin and exocrine pancreatic secretion in dog. (1978) (6)
- Ser-268 Plays an Important Role in Ligand Binding of Prostaglandin E2Receptor EP3αSubtype (1996) (5)
- Immunoassay detection of drugs in racing horses. IV. Detection of fentanyl and its congeners in equine blood and urine by a one step ELISA assay. (1988) (5)
- Radioimmunoassay for etorphine in horses with a 125I analog of etorphine. (1988) (5)
- 14-3-3zeta interacts with human thromboxane receptors and is involved in the agonist-induced activation of the extracellular-signal-regulated kinase. (2006) (5)
- Purification and assay of 9-hydroxyprostaglandin dehydrogenase from rat kidney. (1982) (5)
- Bacterial expression of functional membrane-bound thromboxane synthase having intact sequence and truncated N-terminal hydrophobic segment. (1995) (5)
- Structure and function of human NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase. (2002) (5)
- Increase in enzyme activities of prostaglandin biosynthesis and catabolism by acute ureteral ligation in rat kidney. (1985) (5)
- Monoclonal anti-idiotypic antibody to a potent thromboxane A2 receptor antagonist and its interaction with thromboxane A2 receptor. (1993) (5)
- Purification and characterization of an NAD(+)-dependent dehydrogenase that catalyzes the oxidation of thromboxane B2 at C-11 from porcine liver. Development and application of 11-dehydro-thromboxane B2 radioimmunoassay to enzyme assay. (1990) (5)
- 15-Hydroxyprostaglandin Dehydrogenase Protein Expression in Human Fetal Membranes With and Without Subclinical Inflammation (2007) (5)
- Ser-268 plays an important role in ligand binding of prostaglandin E2 receptor EP3alpha subtype. (1996) (4)
- Oxygen radicals in the nonvagal component of noncholinergic airway constriction. (1996) (4)
- Polycyclic aromatic hydrocarbons affect the calcium ionophore induced activation of rabbit platelet (1990) (4)
- A radioimmunoassay for prostaglandin endoperoxide synthetase. (1984) (4)
- Expression of the cDNA for NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase as a catalytically active enzyme in Escherichia coli. (1992) (4)
- Regulatory mechanism of arachidonic acid metabolism in rat basophilic leukemia (RBL)-2H3 cells. (1987) (4)
- Immunoassay detection of drugs in racing horses: detection of ethacrynic acid and bumetanide in equine urine by ELISA. (1994) (4)
- Partial characterization of a low-molecular-weight, macrophage-derived inhibitor of DNA synthesis: a possible immunoregulatory molecule. (1989) (3)
- Expression and Stimulates Cell Proliferation in Human Lung Cancer Cells (2009) (3)
- Purification and characterization of phosphatidylinositol kinase from porcine liver microsomes. (1988) (3)
- INHIBITION OF 15‐HYDROXYPROSTAGLANDIN DEHYDROGENASE ACTIVITY BY NEAR‐ULTRAVIOLET LIGHT AND TRYPTOPHAN PHOTOPRODUCTS * (1979) (3)
- Immunoassay detection of drugs in racing horses. VII. Detection of acepromazine in equine urine and blood by ELISA and PCFIA. (1988) (3)
- Site-directed mutagenesis studies of the NADPH-binding domain of rat steroid 5alpha-reductase (isozyme-1) I: analysis of aromatic and hydroxylated amino acid residues. (1999) (3)
- Formation of Prostaglandin E 2 and Prostaglandin D 2 Via the Isoprostane Pathway: A Mechanism for the Generation of Bioactive Prostaglandins Independent of the Cyclooxygenase (2003) (3)
- Stimulation of 12-lipoxygenase activity in rat platelets by 17 beta-estradiol. (1982) (3)
- Expression of rat steroid 5α-reductase (isozyme-1) in Spodoptera Frugiperda, SF21, insect cells: Expression of rat steroid 5α-reductase (1997) (3)
- Immunoassay detection of drugs in racing horses. VI. Detection of furosemide (Lasix) in equine blood by a one step ELISA and PCFIA. (1988) (3)
- Rubber additives inhibit the calcium ionophore and thrombin induced activation of rabbit platelets (1991) (2)
- Kinetic evidence of a distinct regulatory site on 15-hydroxyprostaglandin dehydrogenase. (1976) (2)
- Quantitation of 13-hydroxyoctadecadienoic acid (13-HODE) by radioimmunoassay. (1990) (2)
- Regulation of arachidonate release by G-proteins and protein kinase C in human platelets. (1989) (2)
- Assay of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase using (15S)-[15-3H]PGE2. (1982) (2)
- Effects of estradiol on arachidonate metabolism in the rat vascular system. (1985) (2)
- Molecular, catalytic, and immunological characterization of NAD+-linked 15-hydroxyprostaglandin dehydrogenase. (1985) (2)
- A sensitive enzyme immunoassay for cyclosporin A using antibodies generated against a novel hapten. (1995) (2)
- Cloning, Expression and Site-Directed Mutagenesis of the cDNA for Human Placental NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase (1991) (2)
- Expression of rat steroid 5 alpha-reductase (isozyme-1) in Spodoptera frugiperda, SF21, insect cells: expression of rat steroid 5 alpha-reductase. (1997) (2)
- [Isolation and purification of a NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase from human placenta]. (1993) (1)
- Improved sensitivity of enzyme immunoassay for cocaine and benzoylecgonine using heterologous hapten-enzyme conjugates (1994) (1)
- Butyric acid enhances cyclooxygenase activity in rat basophilic leukemia 2H3 cells. (1988) (1)
- A sensitive and specific radioimmunoassay for platelet-activating factor (1992) (1)
- Intracellular translocation of rap 1-B G-protein induced by prostaglandin E1 is blocked by phorbol ester in human platelets. (1994) (1)
- AN 125I‐LABELED N6‐SUBSTITUTED AZIDO ANALOG OF NAD+ FOR THE PHOTOAFFINITY LABELING OF NAD+‐LINKED ENZYMES (1994) (1)
- Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD−/−) mice due to requirement for embryo 15-HPGD activity (2019) (1)
- [Effects of platelet activating factor (PAF:AGEPC) on airway and pulmonary vascular constriction of guinea pigs--with special reference to the relation with TXA2]. (1983) (1)
- Immunological studies on thromboxane synthase. (1987) (1)
- Immunoassay detection of drugs in racing horses. IX. Detection of detomidine in equine blood and urine by radioimmunoassay. (1989) (1)
- Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification. (1989) (1)
- (15-PGDH) BEHAVES AS A TUMOR SUPPRESSOR IN LUNG CANCER 1 (2004) (1)
- [Rat basophilic leukemia-1 cell possesses 12-lipoxygenase and 5-lipoxygenase activities which are specifically inhibited by gossypol acetic acid]. (1984) (1)
- Thiamine transporter gene expression and exogenous thiamine modulate expression of genes in breast and lung cancers (2004) (1)
- Assay of thromboxane A synthase inhibitors. (1982) (1)
- [17] Assay of thromboxane a synthase inhibitors☆ (1982) (1)
- Improved synthesis of (5Z)-7-(3-endo-[(benzenesulfonamido)-bicyclo[2.2.1]heptyl]hept-5-enoic acid (S-145) derivatives and their iodine-125-labeled radioligands for the study of thromboxane A2 receptor. (1993) (1)
- Synergism between chemotactic peptide and platelet-activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils. (1989) (1)
- Characterization of (5Z)-7-[3-endo-[(4-iodophenylsulfonyl) amino] -bicyclo[2.2.1]hep-2-exo-yl]heptenoic acid (IS-145) as an antagonist for the study of thromboxane A2 receptor. (1993) (0)
- Purification and characterization of a novel GTP-binding protein from human platelet cytosol (1987) (0)
- STRUCTURE AND FUNCTION OF PROSTANOID (1997) (0)
- Photoaffinity labeling of NAD(+)-linked enzymes. (1997) (0)
- Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cells (2005) (0)
- Possible mechanisms of cigarette smoke induced decrease in NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-OH-PGDH) activity in lung (1984) (0)
- Composition of, Method of Producing and Method of Using a Stabilized Formulation for Assaying Peroxide Activity (2018) (0)
- Thromboxanes: Synthase and Receptors (1998) (0)
- Mecham of Prostaglandin Biosynthesis in Rabbit Kidney Medulla (2005) (0)
- Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils. (1990) (0)
- TZDs suppress PGE2 via COX-2 dependent and independent pathways in NSCLC. (2006) (0)
- [Effect of cigarette smoking on platelet-thromboxane A2 and arterial-prostacyclin synthesis in rats]. (1988) (0)
- Abnormal platelet response to thromboxane A2 (2018) (0)
- Assay of prostacyclin synthase using [5,6-3H]PGH2. (1982) (0)
- Structure and function of prostaglandin metabolic enzymes (1999) (0)
- Radioimmunoassay of 11-keto-TXB/sub 2/ and its use in the assay and purification of 11-hydroxythromboxane B/sub 2/ dehydrogenase from porcine liver (1987) (0)
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