Hiroyoshi Hidaka
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Hiroyoshi Hidakachemistry Degrees
Chemistry
#1452
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Organic Chemistry
#172
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#219
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Chemistry
Hiroyoshi Hidaka's Degrees
- PhD Chemistry University of Tokyo
- Masters Chemistry University of Tokyo
- Bachelors Chemistry University of Tokyo
Why Is Hiroyoshi Hidaka Influential?
(Suggest an Edit or Addition)Hiroyoshi Hidaka's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. (1984) (2497)
- Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. (1990) (1528)
- KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II. (1990) (612)
- N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. (1981) (563)
- The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells. (1991) (526)
- Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. (1987) (494)
- MAPKAP kinase‐2; a novel protein kinase activated by mitogen‐activated protein kinase. (1992) (450)
- Estrogen increases endothelial nitric oxide by a receptor-mediated system. (1995) (421)
- Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial. (1992) (416)
- Tissue-specific expression of three distinct types of rabbit protein kinase C (1987) (406)
- 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase C in rabbit platelets. (1984) (403)
- Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression (1982) (396)
- Pharmacology of protein kinase inhibitors. (1992) (385)
- Hydrophobic regions function in calmodulin-enzyme(s) interactions. (1980) (318)
- Calcium-regulated modulator protein interacting agents inhibit smooth muscle calcium-stimulated protein kinase and ATPase. (1980) (312)
- The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway. (2002) (253)
- Ca2+ -calmodulin-dependent phosphorylation and platelet secretion (1980) (242)
- Cell type-specific expression of protein kinase C isozymes in the rabbit cerebellum. (1988) (227)
- Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. (1984) (216)
- Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains (1983) (212)
- Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle. (1988) (185)
- Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. (1979) (180)
- A novel vascular relaxing agent, N-(6--aminohexyl)-5-chloro-1-naphthalensulfonamide which affects vascular smooth muscle actomyosin. (1978) (172)
- Development of specific Rho-kinase inhibitors and their clinical application. (2005) (171)
- The structure of calcyclin reveals a novel homodimeric fold for S100 Ca2+-binding proteins (1995) (166)
- Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. (2000) (164)
- Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. (2003) (157)
- Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives. (1981) (156)
- A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. (1989) (155)
- Mechanism of action of a novel antivasospasm drug, HA1077. (1987) (154)
- Two types of calcium-dependent protein phosphorylations modulated by calmodulin antagonists. Naphthalenesulfonamide derivatives. (1982) (147)
- Fusaric acid, a hypotensive agent produced by fungi. (1969) (147)
- Phosphorylation of smooth muscle heavy meromyosin by calcium-activated, phospholipid-dependent protein kinase. The effect on actin-activated MgATPase activity. (1983) (147)
- Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors (1987) (147)
- Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. (1991) (143)
- Inhibition of Rho‐kinase‐induced myristoylated alanine‐rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H‐1152, a novel and specific Rho‐kinase inhibitor (2002) (142)
- Calcium/Calmodulin-dependent Phosphorylation and Activation of Human Cdc25-C at the G2/M Phase Transition in HeLa Cells* (1999) (139)
- Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. (1994) (137)
- Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase (1989) (134)
- Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. (1984) (133)
- Calmodulin and cell proliferation. (1982) (133)
- Human blood platelet 3': 5'-cyclic nucleotide phosphodiesterase. Isolation of low-Km and high-Km phosphodiesterase. (1976) (131)
- Phosphorylation of myosin light chain kinase by the multifunctional calmodulin-dependent protein kinase II in smooth muscle cells. (1992) (129)
- Ca2+ signaling and intracellular Ca2+ binding proteins. (1996) (126)
- Effects of KN-62, a specific inhibitor of calcium/calmodulin-dependent protein kinase II, on long-term potentiation in the rat hippocampus (1991) (126)
- Properties and use of H-series compounds as protein kinase inhibitors. (1991) (126)
- Naphthalenesulfonamides as calmodulin antagonists. (1983) (121)
- Inhibition of voltage-gated Ca2+ channels and insulin secretion in HIT cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-62: comparison with antagonists of calmodulin and L-type Ca2+ channels. (1992) (117)
- Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation. (1984) (116)
- Inhibition of dopamine beta-hydroxylase by sulfhydryl compounds and the nature of the natural inhibitors. (1967) (114)
- Purification and characterization of adipose tissue S-100b protein. (1983) (114)
- Calcium-dependent affinity chromatography of S-100 and calmodulin on calmodulin antagonist-coupled Sepharose. (1981) (114)
- Full sequence of neurocalcin, a novel calcium-binding protein abundant in central nervous system. (1992) (113)
- The effects of HA compound calcium antagonists on delayed cerebral vasospasm in dogs. (1986) (112)
- Effects of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide and other calmodulin antagonists (calmodulin interacting agents) on calcium-induced contraction of rabbit aortic strips. (1981) (111)
- N-(2-Aminoethyl)-5-isoquinolinesulfonamide, a newly synthesized protein kinase inhibitor, functions as a ligand in affinity chromatography. Purification of Ca2+-activated, phospholipid-dependent and other protein kinases. (1985) (108)
- Phosphorylation of smooth muscle myosin light chain kinase by Ca2+-activated, phospholipid-dependent protein kinase. (1985) (105)
- Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system (1993) (103)
- The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins. (1998) (103)
- Stimulation of human platelet guanylate cyclase by unsaturated fatty acid peroxides. (1977) (103)
- Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation. (1979) (102)
- Promotion of granule cell survival by high K+ or excitatory amino acid treatment and Ca2+/calmodulin-dependent protein kinase activity (1993) (101)
- Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase. (1976) (99)
- Vasodilatory action of HA1004 [N-(2-guanidinoethyl)-5-isoquinolinesulfonamide], a novel calcium antagonist with no effect on cardiac function. (1984) (99)
- Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives. (1982) (99)
- H-series protein kinase inhibitors and potential clinical applications. (1999) (97)
- Interaction of local anesthetics with calmodulin. (1981) (97)
- The modulatory role of myosin light chain phosphorylation in human platelet activation. (1986) (95)
- Axokinin phosphorylation by cAMP-dependent protein kinase is sufficient for activation of sperm flagellar motility (1986) (92)
- Neurocalcin, a novel calcium binding protein with three EF-hand domains, expressed in retinal amacrine cells and ganglion cells. (1992) (90)
- A calcyclin-associated protein is a newly identified member of the Ca2+/phospholipid-binding proteins, annexin family. (1992) (87)
- Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades. (1996) (86)
- Hyperpolarizing muscarinic responses of freshly dissociated rat hippocampal CA1 neurones. (1993) (82)
- Purification and characterization of Ca2+/calmodulin-dependent protein kinase V from rat cerebrum. (1993) (81)
- Effects of various calmodulin antagonists on contraction of rabbit aortic strips. (1982) (79)
- Biphasic effect of estrogen on neuronal constitutive nitric oxide synthase via Ca(2+)-calmodulin dependent mechanism. (1994) (79)
- Presence and possible involvement of Ca/calmodulin-dependent protein kinases in insulin release from the rat pancreatic beta cell. (1993) (76)
- Ca2+-activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins. (1984) (76)
- Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors. (1986) (74)
- Ca2+/calmodulin and cyclic 3,5' adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic beta-cell. (1996) (73)
- Phosphorylation of high-Mr caldesmon by protein kinase C modulates the regulatory function of this protein on the interaction between actin and myosin. (1990) (73)
- Ca2+-phospholipid dependent phosphorylation of smooth muscle myosin. (1982) (72)
- Inhibition of platelet aggregation and stimulation of guanylate cyclase by an antianginal agent molsidomine and its metabolites. (1982) (72)
- Effect of novel specific myosin light chain kinase inhibitors on Ca2+-activated Mg2+-ATPase of chicken gizzard actomyosin. (1979) (71)
- A role of calcyclin, a Ca(2+)-binding protein, on the Ca(2+)-dependent insulin release from the pancreatic beta cell. (1994) (69)
- Ca2+ regulated modulator protein interacting agents: inhibition of Ca2+-Mg2+-ATPase of human erythrocyte ghost. (1979) (68)
- HMN-176, an active metabolite of the synthetic antitumor agent HMN-214, restores chemosensitivity to multidrug-resistant cells by targeting the transcription factor NF-Y. (2003) (68)
- Differential localization of protein kinase C isozymes in retinal neurons (1991) (67)
- Neurocalcin: a novel calcium-binding protein from bovine brain. (1992) (67)
- Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. (1984) (66)
- Phosphorylation of Synaptic Vesicle Protein 2 Modulates Binding to Synaptotagmin* (2000) (66)
- The roles of Ca2+/calmodulin- and cGMP-dependent pathways in gametogenesis of a rodent malaria parasite, Plasmodium berghei. (1993) (66)
- Purification and characterization of a new member of the S-100 protein family from human placenta. (1992) (66)
- Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. (1988) (66)
- Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle. (1991) (65)
- Characterization of a calcium/calmodulin-dependent protein kinase homolog from maize roots showing light-regulated gravitropism (2004) (65)
- Thyroid hormones directly interact with vascular smooth muscle strips. (1989) (64)
- Inhibition of acid secretion in gastric parietal cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-93. (1993) (64)
- S-100 protein and calmodulin levels in cerebrospinal fluid after subarachnoid hemorrhage. (1985) (61)
- A fourth type of rabbit protein kinase C. (1988) (61)
- CAP-50, a newly identified annexin, localizes in nuclei of cultured fibroblast 3Y1 cells. (1992) (61)
- Fusaric (5-Butylpicolinic) Acid, an Inhibitor of Dopamine β-Hydroxylase, affects Serotonin and Noradrenaline (1971) (61)
- Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors. (1977) (60)
- Specific binding of a novel compound, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide (H-8) to the active site of cAMP-dependent protein kinase. (1987) (60)
- Endothelin: a potential modulator of cerebral vasospasm. (1990) (59)
- Activation of myosin light chain kinase by trypsin. (1980) (59)
- Phosphorylation of caldesmon by protein kinase C. (1985) (57)
- Regulation of Calcyclin (S100A6) Binding by Alternative Splicing in the N-terminal Regulatory Domain of Annexin XI Isoforms* (1998) (57)
- Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell. (2000) (57)
- Role of calmodulin in platelet aggregation. Structure-activity relationship of calmodulin antagonists. (1982) (56)
- Suggestion for a dibaryon resonance in the pp system (1977) (55)
- Platelet cyclic 3':5'-nucleotide phosphodiesterase released by thrombin and calcium ionophore. (1976) (54)
- Modulation of tyrosine phosphorylation of p36 and other substrates by the S-100 protein. (1988) (54)
- Effects on calmodulin of bepridil, an antianginal agent. (1984) (53)
- Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes. (1992) (53)
- Immunocytochemical evidence for translocation of protein kinase C in human megakaryoblastic leukemic cells: synergistic effects of Ca2+ and activators of protein kinase C on the plasma membrane association (1988) (52)
- Calcium‐dependent association of annexin VI, protein kinase Cα, and neurocalcinα on the raft fraction derived from the synaptic plasma membrane of rat brain (2001) (51)
- Calvasculin, an encoded protein from mRNA termed pEL-98, 18A2, 42A, or p9Ka, is secreted by smooth muscle cells in culture and exhibits Ca(2+)-dependent binding to 36-kDa microfibril-associated glycoprotein. (1992) (51)
- Contractile response of isolated rabbit aortic strips to unsaturated fatty acid peroxides. (1979) (51)
- Thyroid hormones inhibit platelet function and myosin light chain kinase. (1989) (50)
- Calmodulin antagonists' binding sites on calmodulin. (1983) (50)
- Purified rabbit brain protein kinase C relaxes skinned vascular smooth muscle and phosphorylates myosin light chain. (1987) (50)
- Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase--basic and potential clinical applications. (1984) (49)
- Neuroprotective properties of a protein kinase inhibitor against ischaemia‐induced neuronal damage in rats and gerbils (1996) (49)
- Purification, characterization, and partial sequence analysis of a newly identified EF-hand type 13-kDa Ca(2+)-binding protein from smooth muscle and non-muscle tissues. (1991) (49)
- Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. (1984) (49)
- N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. (1986) (48)
- Antitumor effect of a calmodulin antagonist on the growth of solid sarcoma-180. (1983) (47)
- Different expression of protein kinase C isozymes in pancreatic islet cells. (1990) (47)
- Assessment of protein kinase C isozymes by two‐site enzyme immunoassay in human brains and changes in Alzheimer's disease (1993) (46)
- Protein kinase C activation and protooncogene expression in differentiation/retrodifferentiation of human U-937 leukemia cells. (1991) (45)
- Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation. (1988) (45)
- Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester. (1990) (45)
- Low level hyperlipidemia impairs endothelium-dependent relaxation of porcine coronary arteries by two mechanisms. Functional change in endothelium and impairment of endothelium-dependent relaxation by two mediators. (1991) (45)
- The long amino-terminal tail domain of annexin XI is necessary for its nuclear localization. (1995) (45)
- Kinase requirement for retinal growth cone motility. (1994) (45)
- Coexpression of neurocalcin with other calcium‐binding proteins in the rat main olfactory bulb (1999) (45)
- Hippocalcin in rat retina. Comparison with calbindin-D28k, calretinin and neurocalcin. (1995) (45)
- 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine(H-7), a potent inhibitor of protein kinases, inhibits the differentiation of HL-60 cells induced by phorbol diester. (1986) (44)
- Blockade of intracellular actions of calcium may protect against ischaemic damage to the gerbil brain (1991) (44)
- A new assay of cyclic nucleotide phosphodiesterase; its application to human serum. (1974) (44)
- ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation. (1988) (44)
- Binding site of annexin XI on the calcyclin molecule. (1993) (43)
- Isolation and characterization of a calcium-binding protein derived from mRNA termed p9Ka, pEL-98, 18A2, or 42A by the newly synthesized vasorelaxant W-66 affinity chromatography. (1992) (43)
- Selective inhibitors of three forms of cyclic nucleotide phosphodiesterases (1984) (43)
- Ca2+-calmodulin Mediated Modulation of the Electrical Coupling of Ventricular Myocytes Isolated from Guinea Pig Heart (1994) (43)
- In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176 (2003) (42)
- Ca2+-calmodulin dependent phosphorylation of myelin isolated from rabbit brain. (1980) (42)
- S-100 antigen in human T lymphocytes. (1982) (41)
- Vitamin A acid-induced activation of Ca2+-activated, phospholipid-dependent protein kinase from rabbit retina. (1984) (41)
- Structure of the mouse tyrosine hydroxylase gene. (1992) (40)
- zeta-Related protein kinase C in nuclei of nerve cells. (1990) (40)
- The effect of KN-62, Ca2+/calmodulin dependent protein kinase II inhibitor on cell cycle. (1994) (40)
- Transmembrane Ca2+ signaling and a new class of inhibitors. (1987) (39)
- Molecular pharmacology of calmodulin pathways in the cell functions. (1992) (39)
- Biopharmacological Properties of Naphthalenesulfonamides as Potent Calmodulin Antagonists (1984) (39)
- Gonadotropin response to luteinizing hormone releasing hormone in hyperthyroid patients with menstrual disturbances. (1981) (38)
- Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. (1983) (38)
- Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+. (1998) (38)
- Two forms of Ca2+-dependent cyclic 3':5'-nucleotide phosphodiesterase from human aorta and effect of free fatty acids. (1978) (38)
- Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C alpha. (1992) (37)
- Cyclic 3':5'-nucleotide phosphodiesterase determined in various human tissues by DEAE-cellulose chromatography. (1977) (37)
- Expression of three major protein kinase C isozymes in various types of human leukemic cells. (1991) (37)
- The Effect of the H-1152P, a Potent Rho-Associated Coiled Coil-Formed Protein Kinase Inhibitor, in Rabbit Normal and Ocular Hypertensive Eyes (2009) (37)
- Different roles of protein kinase C-β and -δ in arachidonic acid cascade, superoxide formation and phosphoinositide hydrolysis (1993) (37)
- Inhibition of insulin secretion by KN-62, a specific inhibitor of the multifunctional Ca2+/calmodulin-dependent protein kinase II. (1992) (37)
- Isolation and characterization of a 36-kDa microfibril-associated glycoprotein by the newly synthesized isoquinolinesulfonamide affinity chromatography. (1994) (37)
- Characterization of Agonist‐Induced Down‐Regulation of NMDA Receptors in Cerebellar Granule Cell Cultures (1996) (37)
- Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells. (1992) (36)
- A selective Ca2+/calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells. (1991) (36)
- Effect of a new Ca2(+)-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat. (1990) (36)
- Alteration of platelet aggregation in patients with thyroid disorders. (1997) (36)
- Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms. (1997) (35)
- An inhibitor of protein kinase C, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine(H-7) inhibits TPA-induced reduction of vincristine uptake from P388 murine leukemic cell. (1986) (35)
- Effects of adrenomedullin on rat cerebral arterioles. (1997) (34)
- Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. (1999) (34)
- Neurocalcin immunoreactivity in rat olfactory bulb (1993) (34)
- Cloning and expression of a cDNA encoding a new neurocalcin isoform (neurocalcin alpha) from bovine brain. (1998) (33)
- Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially purified from calf liver. (1984) (33)
- Expression of protein kinase C isozyme in epidermal Langerhans cells of the mouse. (1990) (33)
- Assessment of protein kinase C isozymes by enzyme immunoassay and overexpression of type II in thyroid adenocarcinoma. (1990) (33)
- Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor. (1994) (33)
- Purification, characterization, and partial sequence analysis of a new 25-kDa actin-binding protein from bovine aorta: a SM22 homolog. (1994) (32)
- Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase. (1992) (32)
- Biopharmacological Assessment of Calmodulin Function: Utility of Calmodulin Antagonists (1982) (32)
- EFFECTS OF A NEW CALMODULIN INHIBITOR (W-7) ON GLUCOSE-INDUCED INSULIN RELEASE AND BIOSYNTHESIS (1981) (31)
- Two types of calmodulin antagonists: a structurally related interaction. (1984) (31)
- Cellular events involved in the sensitization of etoposide-resistant cells by inhibitors of calcium-calmodulin-dependent processes. Role for effects on apoptosis, DNA cleavable complex, and phosphorylation. (1996) (30)
- Two types of protein kinase C with different functions in cultured rabbit aortic smooth muscle cells. (1989) (30)
- The Effect of the Rho-Associated Protein Kinase Inhibitor, HA-1077, in the Rabbit Ocular Hypertension Model Induced by Water Loading (2009) (30)
- Bradykinin-induced translocation of protein kinases C in neuroblastoma NCB-20 cell: dependence on 1,2-diacylglycerol content and free calcium. (1989) (29)
- An inhibitor of Ca2+/calmodulin-dependent protein kinase II, KN-62, inhibits cholinergic-stimulated parietal cell secretion. (1992) (28)
- Molecular cloning and sequencing of a cDNA clone encoding a new calcium binding protein, named calgizzarin, from rabbit lung. (1991) (28)
- The Ca2+ -activated protease (calpain) modulates Ca2+/calmodulin dependent activity of smooth muscle myosin light chain kinase. (1987) (28)
- Ca2+/calmodulin-dependent protein kinase kinase cascade. (1994) (28)
- Correlation of conformation and phosphorylation and dephosphorylation of smooth muscle myosin. (1988) (28)
- A calcium-binding protein from rabbit lung cytosol identified as the product of growth-regulated gene (2A9) and its binding proteins. (1991) (27)
- Involvement of calcium in cyclic nucleotide metabolism in human vascular smooth muscle. (1978) (27)
- Neurocalcin-immunoreactive receptor cells in the rat olfactory epithelium and vomeronasal organ (1995) (27)
- Effects of Goniopora toxin, a polypeptide isolated from coral, on electromechanical properties of rabbit myocardium. (1979) (27)
- Myosin light-chain phosphorylation controls insulin secretion at a proximal step in the secretory cascade. (1997) (26)
- Modulation of calmodulin function and of Ca2+-induced smooth muscle contraction by the calmodulin antagonist, HT-74. (1986) (26)
- The 5'-flanking region of the human dopamine beta-hydroxylase gene promotes neuron subtype-specific gene expression in the central nervous system of transgenic mice. (1993) (26)
- Decreased phorbol ester receptor and protein kinase C in P388 murine leukemic cells resistant to etoposide. (1987) (26)
- Phosphorylation of annexin XI (CAP-50) in SR-3Y1 cells. (1993) (26)
- The binding of the calcium channel blocker, bepridil, to calmodulin. (1986) (25)
- Calcium ion regulates the release of lipase of Fusarium oxysporum. (1991) (25)
- Neurocalcin-immunopositive neurons in the rat sensory ganglia (1998) (25)
- Purification of guanylate cyclase from human platelets and effect of arachidonic acid peroxide. (1977) (25)
- Calcium-dependent hydrophobic chromatography of calmodulin, S-100 protein and troponin-C. (1984) (25)
- Protein kinase activity in canine basilar arteries after subarachnoid hemorrhage. (1988) (25)
- Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. (1987) (25)
- HYPERREACTIVE ARTERIAL ENDOTHELIAL CELLS: A CLUE FOR THE TREATMENT OF ATHEROSCLEROSIS (1976) (24)
- Annexin XI may be involved in Ca2+‐ or GTP‐γS‐induced insulin secretion in the pancreatic β‐cell (2000) (24)
- Inhibitory effects of aminoglycosides on renal protein phosphorylation by protein kinase C. (1988) (24)
- Calcyclin-binding site located on the NH2-terminal domain of rabbit CAP-50 (annexin XI): functional expression of CAP-50 in Escherichia coli. (1993) (24)
- Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells. (1987) (24)
- Protein kinase C alpha-mediated chronic signal transduction for immunosenescence. (1997) (24)
- Purification of cyclic adenosine monophosphate phosphodiesterase from human platelets using new-inhibitor Sepharose chromatography. (1984) (24)
- PKC phosphorylates MARCKS Ser159 not only directly but also through RhoA/ROCK. (2006) (23)
- Quantitative modulation of thyroid iodide peroxidase by thyroid stimulating hormone. (1980) (23)
- Calcium-dependent association of annexin VI, protein kinase C alpha, and neurocalcin alpha on the raft fraction derived from the synaptic plasma membrane of rat brain. (2001) (22)
- A rapid separation of bovine brain S-100a and S-100b proteins and related conformation studies. (1983) (22)
- Differential distribution of neurocalcin isoforms in rat spinal cord, dorsal root ganglia and muscle spindle. (1994) (22)
- Development-related and cell-type specific nuclear localization of annexin XI: immunolocalization analysis in rat tissues. (1994) (22)
- Cyclic 3',5'-AMP phosphodiesterase of rabbit aorta. (1975) (22)
- Pharmacological properties of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), a calmodulin antagonist in arterial strips from rats and rabbits. (1985) (22)
- Immunohistochemical localization of neurocalcin in the rat inner ear (1995) (22)
- S100 beta is a target protein of neurocalcin delta, an abundant isoform in glial cells. (1995) (22)
- Phosphorylation of Ca2+/calmodulin-dependent protein kinase V and regulation of its activity. (1993) (22)
- Long‐term depression is induced in Ca2+/calmodulin kinase‐inhibited visual cortex neurons (1992) (22)
- Ca(2+)-calmodulin mediated modulation of the electrical coupling of ventricular myocytes isolated from guinea pig heart. (1994) (22)
- Inhibition of MDR1 gene expression by H-87, a selective inhibitor of cAMP-dependent protein kinase. (1993) (22)
- Antitumor effect of calmodulin antagonist against MH-134 hepatoma, Ehrlich ascites carcinoma and B-16 melanocarcinoma in mice. (1983) (21)
- Distinct regional localization of neurocalcin, a Ca(2+)-binding protein, in the bovine adrenal gland. (1993) (21)
- N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. (1986) (21)
- KN-62, a specific Ca++/calmodulin-dependent protein kinase inhibitor, reversibly depresses the rate of beating of cultured fetal mouse cardiac myocytes. (1994) (21)
- Effects of protein kinase A inhibitor (H-89) on VIP- and GRF-induced release and mRNA expression of prolactin and growth hormone in the chicken pituitary gland. (1998) (21)
- Plant annexin form homodimer during Ca(2+)-dependent liposome aggregation. (1995) (21)
- Modification of cardiac sodium current by intracellular application of cAMP (2004) (21)
- Dose escalation trial of a novel calcium antagonist, AT877, in patients with aneurysmal subarachnoid haemorrhage (2005) (21)
- Characterization of gamma- and delta-subunits of Ca2+/calmodulin-dependent protein kinase II in rat gastric mucosal cell populations. (1994) (21)
- Intracellular Ca++ antagonist, HA1004: pharmacological properties different from those of nicardipine. (1985) (20)
- Human thyroid cyclic nucleotide phosphodiesterase. Its characterization and the effect of several hormones on the activity. (1976) (20)
- Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts (1997) (20)
- CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF HUMAN CEREBROSPINAL FLUID (1975) (20)
- Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation. (1986) (20)
- Neurocalcin-immunopositive nerve terminals in the muscle spindle, Golgi tendon organ and motor endplate (1998) (20)
- Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase. (1985) (19)
- Beta-migrating very low density lipoprotein attenuates endothelium-dependent relaxation in rabbit atherosclerotic aortas. (1989) (19)
- Disorganization by calcium antagonists of actin microfilament in aortic smooth muscle cells. (1987) (19)
- Changes of neurocalcin, a calcium-binding protein, in the brain of patients with Alzheimer' s disease (1996) (19)
- Antitumor effect of dicyclohexylammonium sulfate, a potent inhibitor of spermidine synthase against P388 leukemia. (1982) (19)
- Circumvention of multidrug resistance in P388 murine leukemia cells by a novel inhibitor of cyclic AMP-dependent protein kinase, H-87. (1990) (19)
- Overcoming of vinblastine resistance by isoquinolinesulfonamide compounds in adriamycin-resistant leukemia cells. (1992) (19)
- KN-62, a calcium/calmodulin-dependent protein kinase II inhibitor, inhibits high potassium-stimulated prolactin secretion and intracellular calcium increases in anterior pituitary cells. (1996) (19)
- Calmodulin antagonists enhance calcium binding to calmodulin. (1983) (18)
- Selective binding of L-thyroxine by myosin light chain kinase. (1989) (18)
- Pharmacological Analysis of Urotensin-induced Contraction and Relaxation in Isolated Rabbit Aortas (1979) (18)
- The effects of an intracellular calcium antagonist HA 1077 on delayed cerebral vasospasm in dogs (2005) (18)
- Phosphorylation of caldesmon (1989) (18)
- Thyroid hormones inhibit the Ca2+ calmodulin-induced activation of myosin light chain kinase. (1988) (18)
- Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery. (2006) (18)
- Type-specific expression of protein kinase C isozymes in CNS tumor cells (1990) (18)
- Blood Pressure Decreased by Halobutylpicolinic Acid, an Inhibitor of Dopamine β-Hydroxylase (1972) (18)
- IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. (2014) (18)
- Monoclonal antibody recognition of two subtype forms of protein kinase C in human platelets. (1988) (18)
- Conformational studies of myosin phosphorylated by protein kinase C. (1985) (18)
- 2(1H)-quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities. (1998) (18)
- OCCURRENCE OF A SEROTONIN SULPHOTRANSFERASE IN THE BRAIN (1969) (18)
- Calcyclin and calvasculin exist in human platelets. (1992) (17)
- Inhibitory effects of KN-62, a specific inhibitor of Ca/calmodulin-dependent protein kinase II, on serotonin-evoked Cl− current and 36Cl− efflux in Xenopus oocytes (1991) (17)
- Ca2+-independent stimulation of cyclic GMP-dependent protein kinase by calmodulin. (1980) (17)
- Selective inhibition of dopamine-beta-hydroxylase in the peripheral tissues by 5-dimethyldithiocarbamylpicolinic acid; its effect on stress-induced ulcer, ethanol-induced sleep and blood pressure. (1974) (17)
- Vasodilator effects of C-type natriuretic peptide on cerebral arterioles in rats. (1997) (17)
- Specificity of Tetrahymena calmodulin in activation of calmodulin‐regulated enzymes (1982) (17)
- Formation of serotonin O-sulfate by sulfotransferase of rabbit liver. (1969) (16)
- Demonstration of a Ca2+/calmodulin dependent protein kinase cascade in the hog heart. (1998) (16)
- Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype. (2005) (16)
- Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes (1995) (16)
- Two phosphorylated forms of myosin in thrombin-stimulated platelets. (1988) (16)
- Occurrence and distribution of serotonin-O-sulfotransferase in human brain; a new radioisotopic assay. (1972) (16)
- Localization of neurocalcin-like immunoreactivity in rat cranial motoneurons and spinal cord interneurons (1995) (16)
- Calcium Protein Signaling (2012) (16)
- Analogues of fusaric (5-butylpicolinic) acid as potent inhibitors of dopamine -hydroxylase. (1973) (16)
- Expression of protein kinase C isozyme in human Langerhans' cells. (1990) (15)
- Identification of type III protein kinase C in bovine aortic tissue. (1989) (15)
- Capsaicin-sensitive nerves exert an inhibitory effect on the development of fibrin-induced pulmonary edema in rats. (1989) (15)
- Molecular cloning of rabbit CAP-50, a calcyclin-associated annexin protein. (1992) (15)
- Immunohistochemical evidence for the overexpression of protein kinase C in proliferative diseases of human thyroid. (1991) (15)
- Discrepancy of protein kinase C translocation and platelet aggregation--immunocytobiochemical evidence. (1990) (15)
- Calcium-independent activation of calcium ion dependent cyclic nucleotide phosphodiesterase by synthetic compounds: quinazolinesulfonamide derivatives. (1983) (15)
- Ca2+/calmodulin-dependent protein kinase V: tissue distribution and immunohistochemical localization in rat brain. (1994) (15)
- Selective inhibition of cyclic AMP phosphodiesterase from various human tissues by milrinone, a potent cardiac bipyridine. (1988) (14)
- Demonstration of intracellular localization of calmodulin antagonist by wet-mounting radioautography. (1983) (14)
- Inactivation of serotonin by sulfotransferase system. (1969) (14)
- Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers. (1993) (14)
- Regional differences in cerebral vasomotor control by nitric oxide (1995) (14)
- Inhibition of calmodulin function by CV-159, a novel dihydropyridine compound. (1988) (14)
- Inhibitory effects of KN-93, an inhibitor of Ca2+ calmodulin-dependent protein kinase II, on light-regulated root gravitropism in maize. (1993) (14)
- A newly synthesized bifunctional inhibitor, W-77, enhances adriamycin activity against human ovarian carcinoma cells. (1993) (13)
- Obviation of drug resistance and affinity purification of P-glycoprotein by isoquinolinesulfonamides. (1991) (13)
- Formation of serotonin O-sulfate by rat liver sulfating system. (1966) (13)
- Effect of Acetylcholine on the Norepinephrine‐Induced Positive Chronotropy and Increase in Cyclic Nucleotides of Isolated Rabbit Sinoatrial Node (1979) (13)
- Gamma-aminobutyric acid-induced contraction of the dog basilar artery. (1984) (13)
- [Signal-transduction therapy]. (1995) (13)
- Neurocalcin-like immunoreactivity in the rat esophageal nervous system (1998) (13)
- Studies on chemical modification of monensin. VI. Preparation of C-7 modified monensins via protected 7-oxomonensin and evaluation of their ion transport activity. (1997) (13)
- Effects of coriolan, an antitumor polysaccharide, produced by Coriolus versicolor Iwade. (1980) (13)
- 3':5'-cyclic-nucleotide phosphodiesterases of mammalian sera. (1975) (13)
- Assay of S-100 protein by an enzyme immunoassay method. (1983) (13)
- Fusaric (5-butylpicolinic) acid: its effect on plasma growth hormone. (1973) (13)
- Cascade activation of the calmodulin kinase family. (1997) (13)
- Neurocalcin-α immunoreactivity in the enteric nervous system of young and aged rats (2002) (13)
- Effect of the 1-methyl-4-phenylpyridinium ion on phosphorylation of tyrosine hydroxylase in rat pheochromocytoma PC12h cells (1988) (13)
- IMMUNOHISTOCHEMICAL LOCALIZATION OF PROTEIN KINASE C ISOZYMES IN HUMAN CEREBELLUM, HIPPOCAMPUS AND SPINAL CORD (1991) (12)
- Efficient synthesis of [11C]H-1152, a PET probe specific for Rho-kinases, highly potential targets in diagnostic medicine and drug development ☆ (2012) (12)
- Possible prophylactic potential of HA1077, a Ca2+ channel antagonist and vasodilator, on chronic cerebral vasospasm. (1992) (12)
- Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes. (1998) (12)
- Casein kinases I and II from squid brain exhibit selective neurofilament phosphorylation (1992) (12)
- Stimulation of human platelet guanylate cyclase by nitroso compounds. (1982) (12)
- CHAPTER 2 – Modulation of Ca2+-Dependent Regulatory Systems by Calmodulin Antagonists and Other Agents (1985) (12)
- A Ca2+‐sensitive actin regulatory protein from smooth muscle (1985) (12)
- Neuronal nitric oxide synthase-membrane phospholipid interactions. (1998) (12)
- Increase in S-100b protein content in thyroid carcinoma. (1987) (12)
- Immunohistochemical localization of neurocalcin in human sensory neurons and mechanoreceptors (2000) (12)
- Inhibition of dopamine beta-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo. (1970) (11)
- Protein kinase inhibitors. (1994) (11)
- Structural characterization of the calcium binding protein s100 from adipose tissue. (1985) (11)
- Intracellular Localization of Calmodulin Antagonist (W-7) (1982) (11)
- Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla (1997) (11)
- Neurocalcin-immunoreactive primary sensory neurons in the trigeminal ganglion provide myelinated innervation to the tooth pulp and periodontal ligament (2000) (11)
- Hydrophobic properties of Tetrahymena calmodulin related to the phosphodiesterase activity (1983) (11)
- Relaxant effects of various xanthine derivatives. Relationship to cyclic nucleotide phosphodiesterase inhibition. (1992) (11)
- Roles of intracellular Ca2+ receptors in the pancreatic β-cell in insulin secretion (2004) (11)
- Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters. (2004) (11)
- Novel and selective inhibitors of CaM-kinase II and other calmodulin-dependent enzymes. (1990) (10)
- Regulation of preimplantation development of mouse embryos: effects of inhibition of myosin light-chain kinase, a Ca2+/calmodulin-dependent enzyme. (1996) (10)
- A role of nitric oxide in vasomotor control of cerebral parenchymal arterioles in rats. (1994) (10)
- Carbachol‐induced contraction in the circular muscle of guinea‐pig stomach in calcium‐free solution (1986) (10)
- Alterations in pharmacological receptor activities of rabbit arteries by sulfhydryl reagents. (1983) (10)
- Effects of CDP-choline on striatal dopamine level and behavior in rats. (1981) (10)
- [Inhibitor of calmodulin and calmodulin dependent enzyme]. (1998) (10)
- Identification of a 80 kDa calmodulin-binding protein as a new Ca2+/calmodulin-dependent kinase by renaturation blotting assay (RBA). (1992) (10)
- Molecular pharmacology of protein kinases (1990) (10)
- Oxyhemoglobin enhancement of vasopressin-induced constriction in rat cerebral arterioles. (1994) (10)
- Alteration of norepinephrine release from [3h]-norepinephrine preloaded basilar artery by naphthalenesulfonamides. (1982) (10)
- Phospholipids and regulation of protein kinase reaction. (1981) (10)
- HMN-1180, a small molecule inhibitor of neuronal nitric oxide synthase. (1998) (9)
- Purification and characterization of a novel protein activator of Ca2+/calmodulin-dependent protein kinase I. (1995) (9)
- A rapid and simple assay of serotonin sulfokinase activity. (1967) (9)
- Cyclic 3':5'-nucleotide phosphodiesterase of rabbit sinoatrial node. (1978) (9)
- Effect of calmodulin inhibitors on thyroid hormone secretion. (1986) (9)
- Different sensitivities of Ca2+, calmodulin-dependent cyclic nucleotide phosphodiesterases from rabbit aorta and brain to dihydropyridine calcium channel blockers. (1987) (9)
- Relaxation of isolated rabbit arteries by fusaric (5-butylpicolinic) acid. (1976) (9)
- Modulation of tyrosine kinase activity has multiple actions on insulin release from the pancreatic beta-cell: studies with lavendustin A. (1997) (9)
- Monoclonal antibody assessment of tissue- and species-specific myosin light chain kinase isozymes. (1989) (8)
- Roles of intracellular Ca 2+ receptors in the pancreatic β-cell in insulin secretion (1999) (8)
- Purification and characterization of calcium-calmodulin kinase II from human parathyroid glands. (1991) (8)
- Studies on human iodide peroxidase: its activity in various thyroid disorders. (1975) (8)
- Selective inhibitors of calmodulin-dependent phosphodiesterase and other enzymes. (1988) (8)
- Calcium-dependent interactions of an ionophore A23187 with calmodulin. (1985) (8)
- Alteration of human platelet protein kinase C with normal aging (1993) (8)
- A new system to detect native microaggregates of platelets in vivo, with a novel platelet aggregometer employing laser light scattering. (1998) (8)
- A novel Ca2+/calmodulin-dependent protein kinase lacking autophosphorylation activity in the rabbit heart. (1995) (8)
- Micro-determination of monoamine oxidase using serotonin as substrate. (1967) (8)
- Neurocalcin-alpha immunoreactivity in the enteric nervous system of young and aged rats. (2002) (8)
- Platelet Aggregation and Cyclic Nucleotide Phosphodiesterase Activity in Arteriosclerotic Patients (1978) (8)
- S-100 antigen and calmodulin in human leukemic cells. (1989) (8)
- Calcium-dependent interactions with calmodulin of a fluorescent calmodulin antagonist: N2-dansyl-L-arginine-4-t-butylpiperidine amide. (1983) (8)
- 3':5'-cyclic-nucleotide phosphodiesterase in the bovine pituitary gland. (1983) (8)
- Enhancement of antibody-independent phagocytosis by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7). (1983) (7)
- Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms. (1994) (7)
- Possible involvement of protein kinase C in compaction of preimplantation mouse embryos (1989) (7)
- K-134, a Phosphodiesterase 3 Inhibitor, Prevents Brain Damage by Inhibiting Thrombus Formation in a Rat Cerebral Infarction Model (2012) (7)
- Ca2+-dependent cyclic nucleotide phosphodiesterase is activated by poly(L-aspartic acid). (1985) (7)
- Annexin XI may be involved in Ca2+ - or GTP-gammaS-induced insulin secretion in the pancreatic beta-cell. (2000) (7)
- A new and potent calmodulin antagonist, HF-2035, which inhibits vascular relaxation induced by nitric oxide synthase. (1996) (7)
- POTENTIATION OF THE CONTRACTILE RESPONSE TO ACETYLCHOLINE IN AORTIC STRIPS BY LOW CONCENTRATIONS OF VASCULAR CONTRACTILE AGONISTS (1980) (7)
- Decreased neurocalcin immunoreactivity in sympathetic and parasympathetic neurons of the major pelvic ganglion in aged rats (2001) (7)
- Ca(2+)-independent, phospholipid-activated protein kinase in 3Y1 cells. (1991) (7)
- Identification of two subtypes of protein kinase C in human placenta. (1991) (7)
- CHAPTER 33 – Calmodulin Antagonists and Protein Kinase C (1985) (7)
- INHIBITION OF DOPAMINE β-HYDROXYLASE IN BLOOD VESSELS BY PICOLINIC ACID DERIVATIVES IN VIVO AND THEIR ANTIHYPERTENSIVE EFFECTS (1975) (7)
- Effect of KN-62, Ca2+/calmodulin-dependent protein kinase II inhibitor, on adriamycin resistance of human ovarian cancer cells. (1995) (6)
- Isoform-specific intracellular vesicle formation by recombinant annexin XI-A in Sf9 cells. (1996) (6)
- Multidrug resistance in Yoshida rat ascites hepatoma cell lines. (1992) (6)
- Effect of unsaturated fatty acids on separated form of human platelet cyclic nucleotide phosphodiesterase. (1978) (6)
- Thrombin-induced shape change in human megakaryoblastic leukemic cells, MEG-01, is mediated by protein kinase C. (1992) (6)
- A fluorescent protein kinase C inhibitor: 1-(1-hydroxy-5-isoquinolinylsulfonyl)piperazine. (1988) (6)
- Molecular pharmacology of calcium, calmodulin-dependent myosin phosphorylation in vascular smooth muscle. (1990) (6)
- EFFECT OF ANTI‐THYROID AGENTS, METHIMAZOLE AND PROPYLTHIOURACIL, ON BRAIN NORADRENALINE CONTENT (1977) (6)
- Calcyclin, a calcium-binding protein, which regulates insulin secretion from the permeabilized pancreatic beta-cell. (1997) (6)
- Purification, characterization, and partial sequence analysis of 32-kDa calcimedin from chicken gizzard. (1990) (6)
- Cyclic 3',5'-nucleotide phosphodiesterase activities in the thyroid glands of patients with various disorders. (1980) (6)
- Inhibition of thyroid iodide peroxidase in vivo and in vitro by iproniazid. (1970) (6)
- Neuronal nitric oxide synthase specific autophosphorylation in baculovirus/Sf9 insect cell system. (1996) (5)
- Regional distribution of dopamine and norepinephrine in canine cerebral arteries — effect of pre- or postganglionic sympathetic denervation (1983) (5)
- Ca2+/calmodulin-dependent protein phosphorylation associated with the cytoskeleton of quiescent rat fibroblast (3Y1) cells. (1991) (5)
- Immunocytochemical detection and spatial distribution of myosin light-chain kinase in preimplantation mouse embryos. (1997) (5)
- Protective effects of the calmodulin antagonist bepridil on ischaemia induced in the rat myocardium. (1986) (5)
- Search for the functional substrate proteins of protein kinases and their selective inhibitors. (1990) (5)
- PICOLINIC ACID DERIVATIVES AS INHIBITORS OF DOPAMINE β-HYDROXYLASE IN VIVO; THEIR EFFECTS ON BLOOD PRESSURE AND STRESS ULCER (1973) (5)
- Thrombin-induced translocation of protein kinase C in human megakaryoblastic leukemia cells (MEG-01). (1991) (5)
- Calmodulin and acidic compounds alter basic protein phosphorylation by the protein kinase from human platelets. (1982) (5)
- Serum cyclic 3',5'-nucleotide phosphodiesterase in patients with various thyroid disorders. (1985) (5)
- Selective low level of protein kinase C isozyme in a tumor promoter-dependent mouse leukemia cell line. (1989) (5)
- Involvement of calmodulin and calmodulin binding site in the TSH receptor of thyroid. (1987) (5)
- Calcium-Dependent Regulation of Interactions of Caldesmon with Calcium-Binding Proteins Found in Growth Cones of Chick Forebrain Neurons (2001) (5)
- [Molecular pharmacology on protein kinase C]. (1986) (5)
- Purification and characterization of 81K, heat stable calmodulin-binding protein from bovine brain. (1989) (5)
- Hydrophobic regions of calcium binding proteins (1984) (5)
- Biopharmacological Regulation of Protein Phosphorylation (1987) (5)
- Mepacrine-induced inhibition of human platelet cyclic-GMP phosphodiesterase. (1984) (5)
- The effects of HA1077 on the cerebral circulation after subarachnoid haemorrhage in dogs (2005) (5)
- Evidence for posttranscriptional regulation of transgenic protein kinase C–alpha in T cells (1994) (4)
- Potentiation in various agonists-induced contractions of rabbit mesenteric artery by sulfhydryl reagents. (1983) (4)
- HMN-709, a chlorobenzenesulfonamide derivative, is a new membrane-permeable calmodulin antagonist. (1996) (4)
- A novel isoquinoline sulfonamide protein kinase inhibitor (H-1337) produces long-lasting reduction of IOP (2015) (4)
- Interaction of calcium-binding proteins with calmodulin-dependent guanylate cyclase in Tetrahymena plasma membrane. (1985) (4)
- Investigation of binding proteins for anti-platelet agent K-134 by Drug-Western method. (2007) (4)
- Contraction of smooth muscle in Ca-free solution. (1985) (4)
- CHAPTER 32 – Interaction of W-7, a Calmodulin Antagonist, with Another Ca2+-Binding Protein (1985) (4)
- Identification of Ca2+/calmodulin-dependent protein kinase and endogenous substrate of Fusarium oxysporum. (1992) (4)
- IMMUNOHISTOCHEMICAL LOCALIZATION OF PROTEIN KINASE C ISOZYMES (1992) (4)
- Inhibition of human platelet secretion and of Ca2+, calmodulin-dependent protein phosphorylation by the antiallergic agent GMCHA. (1988) (4)
- KN‐62: A Specific Ca2+/calmodulin‐dependent Protein Kinase Inhibitor as a Putative Function‐searching Probe for Intracellular Signal Transduction (1996) (4)
- TIME0URSE CHANGES IN BLOOD PRESSURE, URINARY EXCRETION OF NOREPINEPHRINE AND DOPAMINE AFTER ADMINISTRATION OF FUSARIC ACID IN A SINGLE DOSE IN ELDERLY HYPERTENSIVE PATIENTS (1976) (4)
- Acidic calmodulin binding protein, ACAMP-81, is MARCKS protein interacting with synapsin I. (1992) (4)
- Inter-isoformal regulation of nitric oxide synthase through heteromeric dimerization. (1998) (4)
- Calmodulin regulation during the cell cycle of mammalian cells. (1981) (4)
- Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy (2005) (4)
- The signal transduction systems and intracellular Ca2+ dynamics in arachidonate-induced platelet activation. (1989) (4)
- Effect of the intracellular calcium antagonist HA1004 on cerebral blood flow in rats. (1988) (4)
- Contractile responses of mammalian cerebral arteries to 15-hydroperoxyarachidonic acid vary in the presence of fusaric acid and verapamil. (1984) (4)
- Prevention of intimal proliferation by cilostamide (1994) (4)
- Neurocalcin‐immunoreactive neurons in the mammalian dorsal root ganglia, including humans (2000) (3)
- HIGH ACTIVITY OF CYCLIC 3′,5′‐NUCLEOTIDE PHOSPHODIESTERASE IN SERA OF PATIENT WITH PHAEOCHROMOCYTOMA (1986) (3)
- [Modifiers of calcium action]. (1993) (3)
- Phosphorylation of bovine brain 81-kDa acidic calmodulin binding protein (ACAMP-81) in vitro. (1991) (3)
- a calmodulin antagonist, inhibits cell proliferation (3)
- Inhibition of thyroid iodide peroxidase by hydrazines and NSD-1055 (4-bromo-3-hydroxybenzyl-oxyamine). (1971) (3)
- Effect of cholera enterotoxin on pacemaker rate and cyclic adenosine 3':5'-monophosphate in isolated rabbit sinoatrial node. (1979) (3)
- Immunocytochemical detection of Ca2+-dependent subspecies of protein kinase C in mouse embryos before and during compaction (1994) (3)
- The effects of an anti‐atherosclerotic drug, pyridinolcarbamate, on heart, vascular and brain biogenic amines (1973) (3)
- The localization of a new antithrombotic agent, cilostazol, in CHO-K1 cells as demonstrated by autoradiography. (1985) (3)
- Inhibition of P-glycoprotein-dependent multidrug resistance by an isoquinolinesulfonamide compound H-87 in rat ascites hepatoma AH66 cells. (1996) (3)
- Plasma dopamine-beta-hydroxylase activity and thyroid suppressibility in Graves' disease. (1979) (3)
- A calcium-binding protein from rabbit lung cytosol identified as the product of growth-regulated gene (2A9) and its binding proteins. (1991) (3)
- Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C. (1988) (3)
- New pharmacological strategies in vascular diseases: a novel intracellular calcium antagonist, HA1077 (AT-877) and cerebral vasospasm. (1990) (3)
- RELAXATION OF ISOLATED AORTA OF THE RABBIT BY PICOLINIC ACIDS (1977) (3)
- KN-62, l-[N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-~-tyrosyl]-4- phenylpiperazine, a Specific Inhibitor of Ca2”/Calmodulin-dependent Protein Kinase II* (2001) (3)
- Myosin light-chain phosphorylation controls insulin secretion at a proximal step in the secretory cascade. (1997) (3)
- 90-kDa S6 kinase is insufficient or not involved in the activation of glycogen synthase induced by insulin. (1996) (3)
- Serum cyclic 3',5'-nucleotide phosphodiesterase activity in myocardial infarction. (1985) (3)
- THE THREE-DIMENSIONAL STRUCTURE OF CA2+-BOUND CALCYCLIN: IMPLICATIONS FOR CA2+-SIGNAL TRANSDUCTION BY S100 PROTEINS, NMR, 20 STRUCTURES (1999) (3)
- Calcium-Dependent Functional Hydrophobic Regions of Calcium-Modulated Proteins (1987) (2)
- Urinary norepinephrine excretion in elderly hypertensive patients during administration of fusaric acid. (1976) (2)
- [Effect of vinpocetine (TCV-3B), a vasodilator agent, on cyclic nucleotide metabolism]. (1982) (2)
- Intracellular signaling by protein kinase C (1989) (2)
- Roles of calcium in the regulation of tyrosine hydroxylase. (1989) (2)
- [Annexin family]. (1998) (2)
- Effect of beta-adrenergic blockade on plasma dopamine-beta-hydroxylase activity and triiodothyronine in hyperthyroidism. (1980) (2)
- Elucidation of molecular mechanism of H-1337, an anti-glaucoma agent (2015) (2)
- [Platelet cyclic nucleotides and calcium]. (1979) (2)
- Cyclic AMP phosphodiesterase from human heart and drug action. (1992) (2)
- Specific inhibition of 40 K protein phosphorylation in platelet by a new antithrombotic agent, d-indobufen. (1989) (2)
- A newly synthesized bifunctional inhibitor, CKA1083, enhances adriamycin activity against human ovarian carcinoma cells. (1997) (2)
- Pharmacology of calmodulin and kinase C antagonists. (1986) (2)
- Clinical and pathological significance of sibling Graves' disease. (1980) (2)
- Biopharmacological assessment of calmodulin function: utility of calmodulin antagonist naphthalenesulfonamide. (1981) (2)
- Identification and characterization of protein kinase C-related enzymes in frog retina. (1991) (2)
- Inhibition of the G1/S transition in A65 cells by H-7, a protein kinase C inhibitor. (1993) (2)
- H-1129 suppresses neovascularization through inhibition of secretion of VEGF and proliferation of vascular endothelial cells (2017) (2)
- CHAPTER 6 – Effects of Calmodulin Antagonists on Cell Proliferation (1985) (2)
- Role of protein phosphorylation in Ca2+ regulated intracellular messenger systems. (1989) (2)
- Intracellular Signal Transduction and Cell Function. (1996) (2)
- Identification of two subtypes of protein kinase C in human placenta (1992) (2)
- Molecular Pharmacology of Myosin Light Chain Phosphorylation of Smooth Muscle and Nonmuscle Cells (1987) (2)
- Ca2+, phospholipid and Ca2+, calmodulin-dependent myosin light chain phosphorylation of smooth muscle and nonmuscle cells. (1988) (2)
- PURIFICATION AND PARTIAL AMINO ACID SEQUENCE OF CALMODULIN FROM FUSARIUM OXYSPORUM (1994) (1)
- Subject Index, Vol. 36, 1988 (1988) (1)
- Effect of somatostatin and dopaminergic agents on bovine pituitary phosphodiesterase activity. (1986) (1)
- Ca2(+)-dependent protein kinase cascade of platelets. (1989) (1)
- Reverse relationship between malignancy and cyclic AMP-dependent protein kinase activity in Yoshida rat ascites hepatomas. (1993) (1)
- Unique inhibitory action of the synthetic compound 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)] amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (CKA-1306) against calcium/calmodulin-dependent protein kinase I. (1998) (1)
- Phorbol esters potentiate glucocorticoid-induced cytotoxicity in CEM-C7 human T-leukemia cell line. (1988) (1)
- Contents, Vol. 53, 1992 (2004) (1)
- Inhibitors of Protein Kinases and Protein Phosphates Contributors (2005) (1)
- Isoquinoline sulfonamides such as fasudil, H-1152, ripasudil and H-1129 produce IOP-lowering and neuroprotective effects through Rho kinase inhibition (2018) (1)
- Protein kinase C and platelets. (1985) (1)
- Inhibitory effect of thyroid hormones on pituitary cyclic AMP phosphodiesterase activity in vitro (1984) (1)
- EFFECT OF DOPAMINE-β-HYDROXYLASE INHIBITOR ON STRESS-INDUCED GASTRIC ULCER (1976) (1)
- Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions (1988) (1)
- [Trend in the development of new inhibitors of cyclic nucleotide metabolism and their clinical application]. (1991) (1)
- [Intracellular calcium signaling and selective inhibitors]. (1988) (1)
- Identification and purification of Ca2+/calmodulin-dependent protein kinase V from human gastric carcinoma. (1996) (1)
- Alpha1-adrenergic stimulation induced hypertrophy in protein kinase C down-regulated cultured cardiac myocytes. (1999) (1)
- d-Indobufen inhibits collagen-induced intracellular calcium mobilization and inositol phosphates formation in human platelets. (1990) (1)
- CHAPTER 25 – Elucidation of Regulatory Mechanism of Tyrosine Hydroxylase and Tryptophan Hydroxylase by Calmodulin Antagonists (1985) (1)
- The role of Ca2+-dependent protein phosphorylation in platelet aggregation (1980) (1)
- Calcium signaling of calcium-binding proteins and drug actions. (1989) (1)
- [Pharmacology on calmodulin: calmodulin antagonist]. (1982) (1)
- Ca2+-channel blockers and calmodulin (1983) (1)
- Increase of vinblastine accumulation by inhibitors of calmodulin-dependent cell functions in rat ascites hepatoma AH66 cells. (1992) (1)
- Platelet aggregation and protein phosphorylation. (1980) (1)
- 2(1H)-Quinolinone Derivatives as Novel Antiarteriostenotic Agents Showing Antithrombotic and Antihyperplastic Activities. (1998) (1)
- Molecular pharmacology of protein kinase C. (1989) (1)
- [Beta-adrenergic modulation of cardiac Na+ current]. (1992) (1)
- S-1 O 0 protein and calmodulin levels in cerebrospinal fluid after subarachnoid hemorrhage (2009) (0)
- Molecular Regulation of Calcium, Calmodulin-Dependent Myosin Phosphorylation (1988) (0)
- Studies on cardiac ingredients of plants. XIII: Chemical modification of gitoxin to cardiotonic compounds without vascular effect. (1997) (0)
- Studies on antitumor activity of Ba s idiomycete polysaccharide (Report 29): Antitumor effect and biological activity of Agaricus heterosistes Heinem et Goss (1981) (0)
- The Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Rho-kinase Inhibitor Fasudil (HA-1077) (2003) (0)
- Aminostilbazolderivat and drug (1995) (0)
- EFFECTOFANTI-THYROID AGENTS,METHIMAZOLEAND PROPYL- THIOURACIL, ON BRAINNORADRENALINECONTENT (1977) (0)
- A globular structure of calcium-bound calmodulin-W-7 complex in solution (1998) (0)
- Future prospective of phosphodiesterase-3 inhibitors as antithorombotic drug (2011) (0)
- [Calcium protein signaling]. (1989) (0)
- Effect of cyclic AMP and cyclic GMP phosphodiesterase on platelet aggregation (1977) (0)
- Nuclear localization of annexin XI, a novel annexin (1994) (0)
- Activation of Ca2+-dependent cyclic nucleotide phospho diesterase by poly-L-aspartic acid and inhibition by calmodu lin antagonsits (1984) (0)
- Effect of myosin light-chain kinase inhibition on premature compaction of preimplantation mouse embryos : Papers Presented from Platform (1996) (0)
- [Molecular pharmacologic approach to cell-communication transduction]. (1989) (0)
- Various Types of Human Leukemic Cells Expression of Three Major Protein Kinase C Isozymes in Updated (2006) (0)
- Platelet strip and vascular contraction - A model of study on platelet and vascular interaction (1982) (0)
- Neurocalcin; its un unique expression and a possible role in the Ca2+-signal transduction system in the neural cells (1994) (0)
- [Biochemical mechanism of blood platelet release reaction, aggregation and adhesiveness]. (1978) (0)
- A method for determining the gene of a target protein with the aid of a medicament (1998) (0)
- [Non-steroidal anti-inflammatory drugs. Suppression of biological response and non-steroidal anti-inflammatory drugs]. (1987) (0)
- Immunohistochemical demonstration of protein kinase C isozymes in mouse oocytes and preimplantation embryos : Abstracts of Papers Presented at the Thirtieth Annual Meeting of the Japanese Teratology Society Miyazaki, Japan, July 12-13, 1990 (1990) (0)
- Contributions of cyclic nucleotides in the genesis of chronotropism in isolated rabbit sinoatrial node (1977) (0)
- Development of inhibitors of protein kinases and their clinical application (1998) (0)
- THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES (1996) (0)
- Immunoaffinity purification of type I protein kinase C. (1990) (0)
- The heterogeneity in calmodulin antagonists’ binding sites (1986) (0)
- A method for determination of the assets of a target proteins with the help of a medication with (1998) (0)
- Platelet function and Ca2+-calmodulin-dependent protein phosphorylation (1982) (0)
- Isoquinoline and drug (1997) (0)
- -111-β VERY LOW DENSITY LIPOPROTEIN ATTENUATES ENDOTHELIUM DEPENDENT RELAXATION IN RABBIT ATHEROSCLEROTIC VESSELS : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1989) (0)
- Isoquinoline derivatives and pharmaceutical (1997) (0)
- -1382- The effect of estrogen on neuronal and endothelial constitutive nitric oxide synthase(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY) (1995) (0)
- Inhibition of dopamine beta-hydroxylase in blood vessels by picolinic acid derivatives in vivo and their anthypertensive effects. (1975) (0)
- Time-Course Changes in Blood Pressure,Urinary Excretion of Norepinephrine and Dopamine After Administration Elderly Hypertensive Patients (1977) (0)
- Signal Transduction Therapy (1996) (0)
- Effects of lysine-naphthalene sulfonamide derivatives on the thrombin induced human platelet aggregation and the release reaction (1981) (0)
- Demonstration of Small Molecular Compound ^3H-W-7 by Means of Light Microscopic Radioautography (1982) (0)
- The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 (2003) (0)
- Ca2+ mobilization controls granule movement of insulin granules (1997) (0)
- Effects of the stereoisomers of antipsychotic agents on rabbit aortic strips (1982) (0)
- 228. Cyclic 3':5' Nucleotide Phosphodiesterase and Calcium-regulated Protein Modulator (Calmodulin) in Human Placenta (1979) (0)
- Co-Expression of iNOS and nNOS in COS-7 Cells and Its Effect on Apoptosis Induced by Serum Deprivation (1997) (0)
- IS PROTEIN KINASE C(PKC)ACTIVATION ESSENTIAL FOR THE HYPERTROPHIC EFFECT OF α_1-ADRENERGIC STIMULATION? (1993) (0)
- Protein kinase A controls movement of secretory granules in the pancreatic β-cell. (1996) (0)
- Newly Synthesized Potent ROCKII Inhibitor Isoquinolinesulfonamide Derivative Remarkably Reduces Intraocular Pressure in Cynomologus Monkey and Rabbit (2008) (0)
- Detection of modified β2-microglobulin (β2m) from amyloid deposits in tenosynovial tissue of carpal tunnel syndrome (CTS) (1994) (0)
- LDL Impairs Endothelium-Dependent Relaxation especially in Hyperlipidemic Porcine Coronary Arteries (1990) (0)
- Cyclic AMP in Leukemic Cell Lysate in Disseminated Intravascular Coagulation (1992) (0)
- PKC induces RhoA activation followed by phosphorylation of MARCKS and MBS in neuroblastoma SH‐SY5Y cells. (2006) (0)
- IDENTIFICATION OF AUTOINHIBITORY AND CALMODULIN-RINDING DOMAINS ON CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE I (1995) (0)
- A newly synthesized selective casein kinase I inhibitor, CK1-7, and affinity purification casein kinase I from bovine testis (1989) (0)
- Effects of myosin light-chain kinase inhibition on the organization of acto-myosin cytoskeleton during preimplantation mouse development : The 35th Annual Meeting of the Japanese Teratology Society (1995) (0)
- Effect of a naphthalenesulfonamide derivative on isolated rabbit blood vessels (1977) (0)
- 80 – IROLE OF Ca2+-REGULATED ACTIVATOR PROTEIN OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE IN VASCULAR SMOOTH MUSCLE ACTOMYOSIN SUPERPRECIPITATION (1978) (0)
- Procede de detection in vivo d'un gene proteique cible a l'aide de medicament (1998) (0)
- Ca2+ regulation in chicken gizzard and bovine aorta actomyosin (1980) (0)
- [Calmodulin dependent regulation of smooth muscle contraction]. (1990) (0)
- Molecular pharmacology of protein phosphorylation in the cell functions. (1993) (0)
- BINDING OF BEPRIDIL, A CALCIUM CHANNEL BLOCKER, TO CALMODULIN : Antianginal Drugs : FREE COMMUNICATIONS (V) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1985) (0)
- Purification, characterization and cDNA cloning of calcyclin-associated protein (CAP-50) (1992) (0)
- [Molecular structure and function of platelet calcium binding protein]. (1987) (0)
- TSH-binding inhibitor IgG in some sera from Hashimoto ' s (2010) (0)
- [Ca2+-dependent phosphorylation of cytoskeleton proteins and its pharmacological control]. (1989) (0)
- 260. Immunological Studies on the Human Fetal-Maternal Interaction : (1980) (0)
- [Pharmacology of calmodulin : calmodulin antagonist (author's transl)]. (1981) (0)
- β-adrenergic modulation of cardiac Na + current : Mechanism of intracellular regulation of cardiac ion channels and its abnormality (1993) (0)
- Development of molecular probes for the research of calmodulin-dependent enzymes. (1992) (0)
- Direct inhibition of myosin light chain kinase by naphthalenesulfonamide derivatives (1985) (0)
- [Blood platelets and cyclic nucleotide metabolism]. (1979) (0)
- Hsp90-binding Compound, H-1129, Produces IOP Lowering And Fibronectin Reduction (2012) (0)
- Oligomerization of Nitric Oxide Synthase (NOS) : Interisoformal Structure-activity Analyses of NOS (1996) (0)
- 2.P.336 Native microaggregates and spontaneous platelet aggregation may present a platelet susceptibility leading to thrombogenesis - detection with an original method using a novel platelet aggregometer employing a laser light scattering (1997) (0)
- How does glucose activate intracellular movement of the insulin granules (1999) (0)
- 118. Metabolic Significance of Cyclic Nucleotides in the Environment for the Gorwth of Fetus (The Third Reptort) : Particularly, the Movement of Cyclic Nucleotide Phosphodiesterase in Serum of Pregnant Woman (1980) (0)
- Aminostilbazolderivate and medical (1995) (0)
- [Enzymatic O-sulfation of serotonin]. (1968) (0)
- Characteristics of antibodies to calmodulin in patients with Graves' disease. (1987) (0)
- Enhancement of antibody-independent phagocytosis by a calmodulin antagonist. (1983) (0)
- Phosphorylation of myosin light chain by Ca2+-activated, phospho-lipid-dependent protein kinase in smooth muscle (1983) (0)
- Two types of calmodulin antagonists: A structurally related interaction (1983) (0)
- Effects of Molsidomine and its metabolites on human platelet aggregation and guanylate cyclase activity (1981) (0)
- 225. Metabolic Significance of C-AMP, C-GMP in the Environment for the Growth of Fetus, (the Second Report) : Particularly, Localization of these Nucleotides in Human Placental Tissue and Changes of Phosphodiesterase Activity (1979) (0)
- Novel and specific Rho-kinase inhibitor, H1152P, directed against the Rho-kinase involved pathway (2001) (0)
- Development of specific Rho-kinase inhibitor and its clinical application (2005) (0)
- [Experimental study on the efficacy of the combined use of Young's solution in myocardial protection by asanguinous cardioplegia]. (1983) (0)
- [Enzyme inhibitors--current status and future scope]. (1991) (0)
- Proceedings: Inhibition of platelet cyclic AMP phosphodiesterase and platelet aggregation. (1974) (0)
- -1132-LDL IMPAIRS ENDOTHELIUM-DEPENDENT RELAXATION ESPECIALLY IN HYPERLIPIDEMIC PORCINE CORONARY ARTERIES : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1990) (0)
- Proceedings: In vivo inhibition of dopamine beta-hydroxylase and blood pressure. (1974) (0)
- A novel dihydropyrldine Ca2+ antagonist, CV159: Biopharmacological properties different from those of nicardipine (1986) (0)
- -0627-THE ROLE OF CALMODULIN IN THE REGULATION OF GAP JUMCTIONAL CONDUCTANCE BETWEEN CARDIAC CELLS (1990) (0)
- Quantitative radioautographic study of intracellular localization of calmodulin antagonist, W-7, in Chinese-hamster ovary cells (2004) (0)
- Chelation of copper reduces inhibition by oxidized lipoproteins of endothelium-dependent relaxation in porcine coronary arteries (2005) (0)
- Effects of Ca2+/CaM kinase II inhibitor (KN-62) on the phosphorylation of the cytoskeletal element in cultured cells. (1991) (0)
- Contents, Vol. 36, 1988 (1984) (0)
- a! 1-ADRENERGIC STIMULATION INDUCED HYPERTROPHY IN PROTEIN KINASE C DOWN-REGULATED CULTURED CARDIAC (1999) (0)
- EFFECTS OF UROPHYSIAL EXTRACTS ON THE CARDIOVASCULAR SYSTEM OF THE CARP, Cyprinus carpio (1983) (0)
- Therapeutic potential of a novel isoquinoline sulfonamide derivative with protein kinase inhibition function, H-1337, in wet AMD (2015) (0)
- Discovery and development of pharmacological probes for protein kinases (1992) (0)
- COMPRISING ATPMMETCS CONUGATED TO PEPTDES OR PEPTIDOMIMETCS (2017) (0)
- 151 Indentification of two subtype forms of protein kinase C in human placenta. (1990) (0)
- Intracellular Localization of the Calmodulin Antagonist (1982) (0)
- Role of Phosphodiesterase III in the Control of Blood Flow (1996) (0)
- Distribution of A23187 in cloned rabbit aortic smooth muscle celles (1984) (0)
- Purification and characterization of Ca2+·phospholipid dependent protein kinase (C kinase) from human platelets (1985) (0)
- .omega.-(ARYLSULFAMIDE)-ALKYLAMINE (1975) (0)
- THE NOVEL CALMODULIN ANTAGONIST HMN-709B (1995) (0)
- Anti-gizzard MLCK monoclonal antibody MM13 inhibits superprecipitation and phosphorylation of bovine aortic smooth muscle actomyosin. (1989) (0)
- [Experimental study on the effects of compositions of cardioplegic solutions on coronary arteries]. (1984) (0)
- Proceedings: Effect of fusaric acid and its derivatives on ethanol induced sleep of mice, stress induced gastric ulcer and blood pressure of rats. (1974) (0)
- Effect of hypophysectomy on cyclic 3',5'-nucleotidemetabolizing enzymes in the rat thyroid gland. (1985) (0)
- Factor NF-Y Multidrug-Resistant Cells by Targeting the Transcription Agent HMN-214 , Restores Chemosensitivity to HMN-176 , an Active Metabolite of the Synthetic Antitumor (2003) (0)
- Studies on Cardiac Ingredients of Plants. XIII : Chemical Modification of Gitoxin to Cardiotonic Compounds without Vascular Contractile Effect (1997) (0)
- Elucidation of the intracellular signal transduction by synthesized compounds (1997) (0)
- Purification of 81K protein, a new calmodulin binding protein from bovine brain (1990) (0)
- Selective inhibitor of platelet cAMP phosphodiesterase, cilostamide, inhibits platelet aggregation (1980) (0)
- Calmodulin interacting agents. (1980) (0)
- CONTRIBUTION OF CYCLIC AMP IN THE DELAYED EFFECT OF NORADRENALINE ON CHRONOTROPISM OF SINOATRIAL NODE WITH SIMULTANEOUS APPLICATION OF NORADRENALINE AND ACETYLCHOLINE (1979) (0)
- [Molecular pharmacology of intracellular calcium signaling]. (1990) (0)
- 1472 – EFFECTS OF A NOVEL MARINE POLYPEPTIDE, GONIOPORA TOXIN, ON ELECTROMECHANICAL PROPERTIES OF RABBIT MYOCARDIUM (1978) (0)
- Effect of 8-substituted cyclic AMP derivatives on soluble guanylate cyclase activity from human platelets. (1981) (0)
- News omega- (arylsulfonamido) alkylamine, their process for the preparation and application in therapeutic (1975) (0)
- Inhibition of dopamine beta-hydroxylase by anti-thyroid agents, methimazole and propylthiouracil. (1977) (0)
- Calvasculin, a new member of the EF-hand protein purified by a newly synthesized vaso-relaxant, W-66, affinity matrix binds to a new extracellular matrix protein. (1991) (0)
- Subject Index, Vol. 53, 1992 (2004) (0)
- 1421 – INHIBITION OF DOPAMINE β-HYDROXYLASE IN VIVO AND IN VITRO BY METHIMAZOL USED IN THE THERAPY OF HYPERTHYROIDISM (1977) (0)
- [Proceedings: Characteristics of thyroid peroxidases in man and their antagonists]. (1974) (0)
- Pharmacological properties of platelet strips. (1983) (0)
- Alterations of neurocalcin, a calcium-binding protein, in Alzheimer’s disease. (1996) (0)
- Relaxation of vascular smooth muscle by inhibitors of calmodulin and cyclic nucleotide dependent protein kinase (1984) (0)
- Preparation of omega-(arylsulfonamido)-alkylamides (1975) (0)
- Conformational Studies of Myosin Phosphorylated by Protein (1985) (0)
- Monoamine oxidase activity of the thyroid glands in thyroid disease. (1969) (0)
- Therapeutic potential of topical administration of H-1129, an isoquinoline sulfonamide derivative, in wet AMD and proliferative diabetic retinopathy (2017) (0)
- Inhibition of human platelet aggregation by Ca2+ reseptive protein (calmodulin) interacting agents. (1980) (0)
- Cyclic Nucleotide Phosphodiesterase in Platelets and Platelet Aggregability (1977) (0)
- Time-course changes in blood pressure, urinary excretion of norepinephrine and dopamine after administration of fusaric acid in a single dose in elderly hypertensive patients. (1976) (0)
- The role of protein phosphorylation on intracellular messenger system. (1988) (0)
- Effects of metabolites of Molsidomine on coronary arteries - Coronary vasodilation and activation of guanylate cyclase (1983) (0)
- Inhibition of platelet aggregation by a novel coronary vasodilator, molsidomine and its metabolites (1982) (0)
- [Molecular pharmacology of intracellular Ca2+ messenger system in cardiovascular function: development and application of selective inhibitors]. (1992) (0)
- Reciprocal control of autonomic nerves to chronotropism through opposing influence of cyclic GMP and cyclic AMP in isolated rabbit. sinoatrial node (1978) (0)
- Circumvention of Multidrug Resistance by Suppression of MDR1 Gene Expression in Multidrug Resistant Cells (1993) (0)
- [Molecular pharmacology on intracellular calcium messenger system]. (1986) (0)
- Symmetric covalent linkage of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) results in novel derivatives with increased inhibitory activities against calcium/calmodulin complex. (1999) (0)
- Blockade ofintracellular actions ofcalcium may protectagainst ischaemic damagetothegerbil brain (1991) (0)
- [Shape change in human megakaryoblastic leukemia cells, MEG-01]. (1992) (0)
- Release reaction of platelet and calcium ion (1984) (0)
- Ca2+/Calmodulin-dcpendeni Protein Kinase V: Tissue Distribution and Immunohistochemical Localization in Rat Brain (1995) (0)
- An anti-glaucoma agent, H-1129, binds to middle domain of Hsp90 (2012) (0)
- [Role of cyclic GMP in blood platelets]. (1982) (0)
- Molecular control of calcium-dependent protein phosphorylation reaction in vascular smooth muscle. (1988) (0)
- Effect of dopamine β-hydroxylase inhibitors on isolated rabbit aorta (1976) (0)
- Dihydrate d'hydrochlorure (s) - (-) 1 (4-fluoroisoquinoline-5-yl)sulfonyle-2-methyl-1,4-homopiperazine (2005) (0)
- Studies on Chemical Modification of Monensin. Part 6. Preparation of C- 7 Modified Monensins via Protected 7-Oxomonensin and Evaluation of Their Ion Transport Activity. (2010) (0)
- [Adrenergic receptor--classification, agonists and antagonists]. (1992) (0)
- Calcium-dependent modulation of calmodulin-dependent enzyme activities by Ca2+-dependent protease (CANP) (1986) (0)
- Inhibition of Acid Secretion in Gastric Parietal Cells by the Ca2+/ Calmodulin-Dependent Protein Kinase II Inhibitor KN-93. (1994) (0)
- [Molecular pharmacological analysis of signal transduction by synthetic compounds]. (1997) (0)
- [Cyclic nucleotides phosphodiesterases inhibitors]. (1991) (0)
- Relaxation of isolated rabbit mesenteric artery by N4-substituted quinazoline derivatives (1981) (0)
- Studies on antitumor activity of Bas idiomycete polysaccharide (Report 32) : Antitumor effect and the mechanism of ATOM prepared from cultured Agari cus blazei (1983) (0)
- Binding of iproniazid to the polymeric forms of iodide peroxidase (1980) (0)
- Selective inhibitors of phosphorylation in smooth muscle. (1987) (0)
- Kinase II in Human B Lymphocytes (1995) (0)
- Detection of modified beta 2-microglobulin (beta 2m) from amyloid deposits in tenosynovial tissue of carpal tunnel syndrome (CTS) (1994) (0)
- The role of PDE in platelets (1995) (0)
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