Hiroyoshi Hidaka

Q: What Schools Are Affiliated With Hiroyoshi Hidaka

Hiroyoshi Hidaka is affiliated with the following schools: Yale University, University of Washington, Kyoto University, Shinshu University

Hiroyoshi Hidaka's AcademicInfluence.com Rankings

Hiroyoshi Hidaka

Chemistry

#1452

World Rank

#2167

Historical Rank

Organic Chemistry

#172

World Rank

#219

Historical Rank

chemistry Degrees

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Chemistry

Hiroyoshi Hidaka's Degrees

PhD Chemistry University of Tokyo
Masters Chemistry University of Tokyo
Bachelors Chemistry University of Tokyo

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Hiroyoshi Hidaka's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. (1984) (2497)
Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. (1990) (1528)
KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II. (1990) (612)
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. (1981) (563)
The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells. (1991) (526)
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. (1987) (494)
MAPKAP kinase‐2; a novel protein kinase activated by mitogen‐activated protein kinase. (1992) (450)
Estrogen increases endothelial nitric oxide by a receptor-mediated system. (1995) (421)
Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial. (1992) (416)
Tissue-specific expression of three distinct types of rabbit protein kinase C (1987) (406)
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase C in rabbit platelets. (1984) (403)
Calmodulin and the cell cycle: Involvement in regulation of cell-cycle progression (1982) (396)
Pharmacology of protein kinase inhibitors. (1992) (385)
Hydrophobic regions function in calmodulin-enzyme(s) interactions. (1980) (318)
Calcium-regulated modulator protein interacting agents inhibit smooth muscle calcium-stimulated protein kinase and ATPase. (1980) (312)
The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway. (2002) (253)
Ca2+ -calmodulin-dependent phosphorylation and platelet secretion (1980) (242)
Cell type-specific expression of protein kinase C isozymes in the rabbit cerebellum. (1988) (227)
Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. (1984) (216)
Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains (1983) (212)
Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle. (1988) (185)
Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction. (1979) (180)
A novel vascular relaxing agent, N-(6--aminohexyl)-5-chloro-1-naphthalensulfonamide which affects vascular smooth muscle actomyosin. (1978) (172)
Development of specific Rho-kinase inhibitors and their clinical application. (2005) (171)
The structure of calcyclin reveals a novel homodimeric fold for S100 Ca2+-binding proteins (1995) (166)
Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. (2000) (164)
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. (2003) (157)
Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives. (1981) (156)
A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis. (1989) (155)
Mechanism of action of a novel antivasospasm drug, HA1077. (1987) (154)
Two types of calcium-dependent protein phosphorylations modulated by calmodulin antagonists. Naphthalenesulfonamide derivatives. (1982) (147)
Fusaric acid, a hypotensive agent produced by fungi. (1969) (147)
Phosphorylation of smooth muscle heavy meromyosin by calcium-activated, phospholipid-dependent protein kinase. The effect on actin-activated MgATPase activity. (1983) (147)
Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors (1987) (147)
Induction of immediate early genes by Ca2+ influx requires cAMP-dependent protein kinase in PC12 cells. (1991) (143)
Inhibition of Rho‐kinase‐induced myristoylated alanine‐rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H‐1152, a novel and specific Rho‐kinase inhibitor (2002) (142)
Calcium/Calmodulin-dependent Phosphorylation and Activation of Human Cdc25-C at the G2/M Phase Transition in HeLa Cells* (1999) (139)
Activation mechanisms for Ca2+/calmodulin-dependent protein kinase IV. Identification of a brain CaM-kinase IV kinase. (1994) (137)
Vasodilator actions of HA1077 in vitro and in vivo putatively mediated by the inhibition of protein kinase (1989) (134)
Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. (1984) (133)
Calmodulin and cell proliferation. (1982) (133)
Human blood platelet 3': 5'-cyclic nucleotide phosphodiesterase. Isolation of low-Km and high-Km phosphodiesterase. (1976) (131)
Phosphorylation of myosin light chain kinase by the multifunctional calmodulin-dependent protein kinase II in smooth muscle cells. (1992) (129)
Ca2+ signaling and intracellular Ca2+ binding proteins. (1996) (126)
Effects of KN-62, a specific inhibitor of calcium/calmodulin-dependent protein kinase II, on long-term potentiation in the rat hippocampus (1991) (126)
Properties and use of H-series compounds as protein kinase inhibitors. (1991) (126)
Naphthalenesulfonamides as calmodulin antagonists. (1983) (121)
Inhibition of voltage-gated Ca2+ channels and insulin secretion in HIT cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-62: comparison with antagonists of calmodulin and L-type Ca2+ channels. (1992) (117)
Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation. (1984) (116)
Inhibition of dopamine beta-hydroxylase by sulfhydryl compounds and the nature of the natural inhibitors. (1967) (114)
Purification and characterization of adipose tissue S-100b protein. (1983) (114)
Calcium-dependent affinity chromatography of S-100 and calmodulin on calmodulin antagonist-coupled Sepharose. (1981) (114)
Full sequence of neurocalcin, a novel calcium-binding protein abundant in central nervous system. (1992) (113)
The effects of HA compound calcium antagonists on delayed cerebral vasospasm in dogs. (1986) (112)
Effects of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide and other calmodulin antagonists (calmodulin interacting agents) on calcium-induced contraction of rabbit aortic strips. (1981) (111)
N-(2-Aminoethyl)-5-isoquinolinesulfonamide, a newly synthesized protein kinase inhibitor, functions as a ligand in affinity chromatography. Purification of Ca2+-activated, phospholipid-dependent and other protein kinases. (1985) (108)
Phosphorylation of smooth muscle myosin light chain kinase by Ca2+-activated, phospholipid-dependent protein kinase. (1985) (105)
Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system (1993) (103)
The three-dimensional structure of Ca(2+)-bound calcyclin: implications for Ca(2+)-signal transduction by S100 proteins. (1998) (103)
Stimulation of human platelet guanylate cyclase by unsaturated fatty acid peroxides. (1977) (103)
Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation. (1979) (102)
Promotion of granule cell survival by high K+ or excitatory amino acid treatment and Ca2+/calmodulin-dependent protein kinase activity (1993) (101)
Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase. (1976) (99)
Vasodilatory action of HA1004 [N-(2-guanidinoethyl)-5-isoquinolinesulfonamide], a novel calcium antagonist with no effect on cardiac function. (1984) (99)
Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives. (1982) (99)
H-series protein kinase inhibitors and potential clinical applications. (1999) (97)
Interaction of local anesthetics with calmodulin. (1981) (97)
The modulatory role of myosin light chain phosphorylation in human platelet activation. (1986) (95)
Axokinin phosphorylation by cAMP-dependent protein kinase is sufficient for activation of sperm flagellar motility (1986) (92)
Neurocalcin, a novel calcium binding protein with three EF-hand domains, expressed in retinal amacrine cells and ganglion cells. (1992) (90)
A calcyclin-associated protein is a newly identified member of the Ca2+/phospholipid-binding proteins, annexin family. (1992) (87)
Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades. (1996) (86)
Hyperpolarizing muscarinic responses of freshly dissociated rat hippocampal CA1 neurones. (1993) (82)
Purification and characterization of Ca2+/calmodulin-dependent protein kinase V from rat cerebrum. (1993) (81)
Effects of various calmodulin antagonists on contraction of rabbit aortic strips. (1982) (79)
Biphasic effect of estrogen on neuronal constitutive nitric oxide synthase via Ca(2+)-calmodulin dependent mechanism. (1994) (79)
Presence and possible involvement of Ca/calmodulin-dependent protein kinases in insulin release from the rat pancreatic beta cell. (1993) (76)
Ca2+-activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins. (1984) (76)
Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors. (1986) (74)
Ca2+/calmodulin and cyclic 3,5' adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic beta-cell. (1996) (73)
Phosphorylation of high-Mr caldesmon by protein kinase C modulates the regulatory function of this protein on the interaction between actin and myosin. (1990) (73)
Ca2+-phospholipid dependent phosphorylation of smooth muscle myosin. (1982) (72)
Inhibition of platelet aggregation and stimulation of guanylate cyclase by an antianginal agent molsidomine and its metabolites. (1982) (72)
Effect of novel specific myosin light chain kinase inhibitors on Ca2+-activated Mg2+-ATPase of chicken gizzard actomyosin. (1979) (71)
A role of calcyclin, a Ca(2+)-binding protein, on the Ca(2+)-dependent insulin release from the pancreatic beta cell. (1994) (69)
Ca2+ regulated modulator protein interacting agents: inhibition of Ca2+-Mg2+-ATPase of human erythrocyte ghost. (1979) (68)
HMN-176, an active metabolite of the synthetic antitumor agent HMN-214, restores chemosensitivity to multidrug-resistant cells by targeting the transcription factor NF-Y. (2003) (68)
Differential localization of protein kinase C isozymes in retinal neurons (1991) (67)
Neurocalcin: a novel calcium-binding protein from bovine brain. (1992) (67)
Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. (1984) (66)
Phosphorylation of Synaptic Vesicle Protein 2 Modulates Binding to Synaptotagmin* (2000) (66)
The roles of Ca2+/calmodulin- and cGMP-dependent pathways in gametogenesis of a rodent malaria parasite, Plasmodium berghei. (1993) (66)
Purification and characterization of a new member of the S-100 protein family from human placenta. (1992) (66)
Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine/threonine protein kinases. (1988) (66)
Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle. (1991) (65)
Characterization of a calcium/calmodulin-dependent protein kinase homolog from maize roots showing light-regulated gravitropism (2004) (65)
Thyroid hormones directly interact with vascular smooth muscle strips. (1989) (64)
Inhibition of acid secretion in gastric parietal cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-93. (1993) (64)
S-100 protein and calmodulin levels in cerebrospinal fluid after subarachnoid hemorrhage. (1985) (61)
A fourth type of rabbit protein kinase C. (1988) (61)
CAP-50, a newly identified annexin, localizes in nuclei of cultured fibroblast 3Y1 cells. (1992) (61)
Fusaric (5-Butylpicolinic) Acid, an Inhibitor of Dopamine β-Hydroxylase, affects Serotonin and Noradrenaline (1971) (61)
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors. (1977) (60)
Specific binding of a novel compound, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide (H-8) to the active site of cAMP-dependent protein kinase. (1987) (60)
Endothelin: a potential modulator of cerebral vasospasm. (1990) (59)
Activation of myosin light chain kinase by trypsin. (1980) (59)
Phosphorylation of caldesmon by protein kinase C. (1985) (57)
Regulation of Calcyclin (S100A6) Binding by Alternative Splicing in the N-terminal Regulatory Domain of Annexin XI Isoforms* (1998) (57)
Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell. (2000) (57)
Role of calmodulin in platelet aggregation. Structure-activity relationship of calmodulin antagonists. (1982) (56)
Suggestion for a dibaryon resonance in the pp system (1977) (55)
Platelet cyclic 3':5'-nucleotide phosphodiesterase released by thrombin and calcium ionophore. (1976) (54)
Modulation of tyrosine phosphorylation of p36 and other substrates by the S-100 protein. (1988) (54)
Effects on calmodulin of bepridil, an antianginal agent. (1984) (53)
Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes. (1992) (53)
Immunocytochemical evidence for translocation of protein kinase C in human megakaryoblastic leukemic cells: synergistic effects of Ca2+ and activators of protein kinase C on the plasma membrane association (1988) (52)
Calcium‐dependent association of annexin VI, protein kinase Cα, and neurocalcinα on the raft fraction derived from the synaptic plasma membrane of rat brain (2001) (51)
Calvasculin, an encoded protein from mRNA termed pEL-98, 18A2, 42A, or p9Ka, is secreted by smooth muscle cells in culture and exhibits Ca(2+)-dependent binding to 36-kDa microfibril-associated glycoprotein. (1992) (51)
Contractile response of isolated rabbit aortic strips to unsaturated fatty acid peroxides. (1979) (51)
Thyroid hormones inhibit platelet function and myosin light chain kinase. (1989) (50)
Calmodulin antagonists' binding sites on calmodulin. (1983) (50)
Purified rabbit brain protein kinase C relaxes skinned vascular smooth muscle and phosphorylates myosin light chain. (1987) (50)
Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase--basic and potential clinical applications. (1984) (49)
Neuroprotective properties of a protein kinase inhibitor against ischaemia‐induced neuronal damage in rats and gerbils (1996) (49)
Purification, characterization, and partial sequence analysis of a newly identified EF-hand type 13-kDa Ca(2+)-binding protein from smooth muscle and non-muscle tissues. (1991) (49)
Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. (1984) (49)
N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. (1986) (48)
Antitumor effect of a calmodulin antagonist on the growth of solid sarcoma-180. (1983) (47)
Different expression of protein kinase C isozymes in pancreatic islet cells. (1990) (47)
Assessment of protein kinase C isozymes by two‐site enzyme immunoassay in human brains and changes in Alzheimer's disease (1993) (46)
Protein kinase C activation and protooncogene expression in differentiation/retrodifferentiation of human U-937 leukemia cells. (1991) (45)
Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation. (1988) (45)
Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester. (1990) (45)
Low level hyperlipidemia impairs endothelium-dependent relaxation of porcine coronary arteries by two mechanisms. Functional change in endothelium and impairment of endothelium-dependent relaxation by two mediators. (1991) (45)
The long amino-terminal tail domain of annexin XI is necessary for its nuclear localization. (1995) (45)
Kinase requirement for retinal growth cone motility. (1994) (45)
Coexpression of neurocalcin with other calcium‐binding proteins in the rat main olfactory bulb (1999) (45)
Hippocalcin in rat retina. Comparison with calbindin-D28k, calretinin and neurocalcin. (1995) (45)
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine(H-7), a potent inhibitor of protein kinases, inhibits the differentiation of HL-60 cells induced by phorbol diester. (1986) (44)
Blockade of intracellular actions of calcium may protect against ischaemic damage to the gerbil brain (1991) (44)
A new assay of cyclic nucleotide phosphodiesterase; its application to human serum. (1974) (44)
ML-9 inhibits the vascular contraction via the inhibition of myosin light chain phosphorylation. (1988) (44)
Binding site of annexin XI on the calcyclin molecule. (1993) (43)
Isolation and characterization of a calcium-binding protein derived from mRNA termed p9Ka, pEL-98, 18A2, or 42A by the newly synthesized vasorelaxant W-66 affinity chromatography. (1992) (43)
Selective inhibitors of three forms of cyclic nucleotide phosphodiesterases (1984) (43)
Ca2+-calmodulin Mediated Modulation of the Electrical Coupling of Ventricular Myocytes Isolated from Guinea Pig Heart (1994) (43)
In vivo antitumor activity of a novel sulfonamide, HMN-214, against human tumor xenografts in mice and the spectrum of cytotoxicity of its active metabolite, HMN-176 (2003) (42)
Ca2+-calmodulin dependent phosphorylation of myelin isolated from rabbit brain. (1980) (42)
S-100 antigen in human T lymphocytes. (1982) (41)
Vitamin A acid-induced activation of Ca2+-activated, phospholipid-dependent protein kinase from rabbit retina. (1984) (41)
Structure of the mouse tyrosine hydroxylase gene. (1992) (40)
zeta-Related protein kinase C in nuclei of nerve cells. (1990) (40)
The effect of KN-62, Ca2+/calmodulin dependent protein kinase II inhibitor on cell cycle. (1994) (40)
Transmembrane Ca2+ signaling and a new class of inhibitors. (1987) (39)
Molecular pharmacology of calmodulin pathways in the cell functions. (1992) (39)
Biopharmacological Properties of Naphthalenesulfonamides as Potent Calmodulin Antagonists (1984) (39)
Gonadotropin response to luteinizing hormone releasing hormone in hyperthyroid patients with menstrual disturbances. (1981) (38)
Complex effects of inhibitors on cyclic GMP-stimulated cyclic nucleotide phosphodiesterase. (1983) (38)
Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+. (1998) (38)
Two forms of Ca2+-dependent cyclic 3':5'-nucleotide phosphodiesterase from human aorta and effect of free fatty acids. (1978) (38)
Accelerated proliferation and interleukin-2 production of thymocytes by stimulation of soluble anti-CD3 monoclonal antibody in transgenic mice carrying a rabbit protein kinase C alpha. (1992) (37)
Cyclic 3':5'-nucleotide phosphodiesterase determined in various human tissues by DEAE-cellulose chromatography. (1977) (37)
Expression of three major protein kinase C isozymes in various types of human leukemic cells. (1991) (37)
The Effect of the H-1152P, a Potent Rho-Associated Coiled Coil-Formed Protein Kinase Inhibitor, in Rabbit Normal and Ocular Hypertensive Eyes (2009) (37)
Different roles of protein kinase C-β and -δ in arachidonic acid cascade, superoxide formation and phosphoinositide hydrolysis (1993) (37)
Inhibition of insulin secretion by KN-62, a specific inhibitor of the multifunctional Ca2+/calmodulin-dependent protein kinase II. (1992) (37)
Isolation and characterization of a 36-kDa microfibril-associated glycoprotein by the newly synthesized isoquinolinesulfonamide affinity chromatography. (1994) (37)
Characterization of Agonist‐Induced Down‐Regulation of NMDA Receptors in Cerebellar Granule Cell Cultures (1996) (37)
Pharmacological manipulation of tissue cyclic AMP by inhibitors. Effects of phosphodiesterase inhibitors on the functions of platelets and vascular endothelial cells. (1992) (36)
A selective Ca2+/calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells. (1991) (36)
Effect of a new Ca2(+)-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat. (1990) (36)
Alteration of platelet aggregation in patients with thyroid disorders. (1997) (36)
Isolation and comparison of rat cDNAs encoding Ca2+/calmodulin-dependent protein kinase I isoforms. (1997) (35)
An inhibitor of protein kinase C, 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine(H-7) inhibits TPA-induced reduction of vincristine uptake from P388 murine leukemic cell. (1986) (35)
Effects of adrenomedullin on rat cerebral arterioles. (1997) (34)
Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: drug-western. (1999) (34)
Neurocalcin immunoreactivity in rat olfactory bulb (1993) (34)
Cloning and expression of a cDNA encoding a new neurocalcin isoform (neurocalcin alpha) from bovine brain. (1998) (33)
Selective inhibition of two soluble adenosine cyclic 3',5'-phosphate phosphodiesterases partially purified from calf liver. (1984) (33)
Expression of protein kinase C isozyme in epidermal Langerhans cells of the mouse. (1990) (33)
Assessment of protein kinase C isozymes by enzyme immunoassay and overexpression of type II in thyroid adenocarcinoma. (1990) (33)
Recombinant human tyrosine hydroxylase types 1-4 show regulatory kinetic properties for the natural (6R)-tetrahydrobiopterin cofactor. (1994) (33)
Purification, characterization, and partial sequence analysis of a new 25-kDa actin-binding protein from bovine aorta: a SM22 homolog. (1994) (32)
Organization and complete nucleotide sequence of the gene encoding mouse phenylethanolamine N-methyltransferase. (1992) (32)
Biopharmacological Assessment of Calmodulin Function: Utility of Calmodulin Antagonists (1982) (32)
EFFECTS OF A NEW CALMODULIN INHIBITOR (W-7) ON GLUCOSE-INDUCED INSULIN RELEASE AND BIOSYNTHESIS (1981) (31)
Two types of calmodulin antagonists: a structurally related interaction. (1984) (31)
Cellular events involved in the sensitization of etoposide-resistant cells by inhibitors of calcium-calmodulin-dependent processes. Role for effects on apoptosis, DNA cleavable complex, and phosphorylation. (1996) (30)
Two types of protein kinase C with different functions in cultured rabbit aortic smooth muscle cells. (1989) (30)
The Effect of the Rho-Associated Protein Kinase Inhibitor, HA-1077, in the Rabbit Ocular Hypertension Model Induced by Water Loading (2009) (30)
Bradykinin-induced translocation of protein kinases C in neuroblastoma NCB-20 cell: dependence on 1,2-diacylglycerol content and free calcium. (1989) (29)
An inhibitor of Ca2+/calmodulin-dependent protein kinase II, KN-62, inhibits cholinergic-stimulated parietal cell secretion. (1992) (28)
Molecular cloning and sequencing of a cDNA clone encoding a new calcium binding protein, named calgizzarin, from rabbit lung. (1991) (28)
The Ca2+ -activated protease (calpain) modulates Ca2+/calmodulin dependent activity of smooth muscle myosin light chain kinase. (1987) (28)
Ca2+/calmodulin-dependent protein kinase kinase cascade. (1994) (28)
Correlation of conformation and phosphorylation and dephosphorylation of smooth muscle myosin. (1988) (28)
A calcium-binding protein from rabbit lung cytosol identified as the product of growth-regulated gene (2A9) and its binding proteins. (1991) (27)
Involvement of calcium in cyclic nucleotide metabolism in human vascular smooth muscle. (1978) (27)
Neurocalcin-immunoreactive receptor cells in the rat olfactory epithelium and vomeronasal organ (1995) (27)
Effects of Goniopora toxin, a polypeptide isolated from coral, on electromechanical properties of rabbit myocardium. (1979) (27)
Myosin light-chain phosphorylation controls insulin secretion at a proximal step in the secretory cascade. (1997) (26)
Modulation of calmodulin function and of Ca2+-induced smooth muscle contraction by the calmodulin antagonist, HT-74. (1986) (26)
The 5'-flanking region of the human dopamine beta-hydroxylase gene promotes neuron subtype-specific gene expression in the central nervous system of transgenic mice. (1993) (26)
Decreased phorbol ester receptor and protein kinase C in P388 murine leukemic cells resistant to etoposide. (1987) (26)
Phosphorylation of annexin XI (CAP-50) in SR-3Y1 cells. (1993) (26)
The binding of the calcium channel blocker, bepridil, to calmodulin. (1986) (25)
Calcium ion regulates the release of lipase of Fusarium oxysporum. (1991) (25)
Neurocalcin-immunopositive neurons in the rat sensory ganglia (1998) (25)
Purification of guanylate cyclase from human platelets and effect of arachidonic acid peroxide. (1977) (25)
Calcium-dependent hydrophobic chromatography of calmodulin, S-100 protein and troponin-C. (1984) (25)
Protein kinase activity in canine basilar arteries after subarachnoid hemorrhage. (1988) (25)
Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. (1987) (25)
HYPERREACTIVE ARTERIAL ENDOTHELIAL CELLS: A CLUE FOR THE TREATMENT OF ATHEROSCLEROSIS (1976) (24)
Annexin XI may be involved in Ca2+‐ or GTP‐γS‐induced insulin secretion in the pancreatic β‐cell (2000) (24)
Inhibitory effects of aminoglycosides on renal protein phosphorylation by protein kinase C. (1988) (24)
Calcyclin-binding site located on the NH2-terminal domain of rabbit CAP-50 (annexin XI): functional expression of CAP-50 in Escherichia coli. (1993) (24)
Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells. (1987) (24)
Protein kinase C alpha-mediated chronic signal transduction for immunosenescence. (1997) (24)
Purification of cyclic adenosine monophosphate phosphodiesterase from human platelets using new-inhibitor Sepharose chromatography. (1984) (24)
PKC phosphorylates MARCKS Ser159 not only directly but also through RhoA/ROCK. (2006) (23)
Quantitative modulation of thyroid iodide peroxidase by thyroid stimulating hormone. (1980) (23)
Calcium-dependent association of annexin VI, protein kinase C alpha, and neurocalcin alpha on the raft fraction derived from the synaptic plasma membrane of rat brain. (2001) (22)
A rapid separation of bovine brain S-100a and S-100b proteins and related conformation studies. (1983) (22)
Differential distribution of neurocalcin isoforms in rat spinal cord, dorsal root ganglia and muscle spindle. (1994) (22)
Development-related and cell-type specific nuclear localization of annexin XI: immunolocalization analysis in rat tissues. (1994) (22)
Cyclic 3',5'-AMP phosphodiesterase of rabbit aorta. (1975) (22)
Pharmacological properties of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), a calmodulin antagonist in arterial strips from rats and rabbits. (1985) (22)
Immunohistochemical localization of neurocalcin in the rat inner ear (1995) (22)
S100 beta is a target protein of neurocalcin delta, an abundant isoform in glial cells. (1995) (22)
Phosphorylation of Ca2+/calmodulin-dependent protein kinase V and regulation of its activity. (1993) (22)
Long‐term depression is induced in Ca2+/calmodulin kinase‐inhibited visual cortex neurons (1992) (22)
Ca(2+)-calmodulin mediated modulation of the electrical coupling of ventricular myocytes isolated from guinea pig heart. (1994) (22)
Inhibition of MDR1 gene expression by H-87, a selective inhibitor of cAMP-dependent protein kinase. (1993) (22)
Antitumor effect of calmodulin antagonist against MH-134 hepatoma, Ehrlich ascites carcinoma and B-16 melanocarcinoma in mice. (1983) (21)
Distinct regional localization of neurocalcin, a Ca(2+)-binding protein, in the bovine adrenal gland. (1993) (21)
N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. (1986) (21)
KN-62, a specific Ca++/calmodulin-dependent protein kinase inhibitor, reversibly depresses the rate of beating of cultured fetal mouse cardiac myocytes. (1994) (21)
Effects of protein kinase A inhibitor (H-89) on VIP- and GRF-induced release and mRNA expression of prolactin and growth hormone in the chicken pituitary gland. (1998) (21)
Plant annexin form homodimer during Ca(2+)-dependent liposome aggregation. (1995) (21)
Modification of cardiac sodium current by intracellular application of cAMP (2004) (21)
Dose escalation trial of a novel calcium antagonist, AT877, in patients with aneurysmal subarachnoid haemorrhage (2005) (21)
Characterization of gamma- and delta-subunits of Ca2+/calmodulin-dependent protein kinase II in rat gastric mucosal cell populations. (1994) (21)
Intracellular Ca++ antagonist, HA1004: pharmacological properties different from those of nicardipine. (1985) (20)
Human thyroid cyclic nucleotide phosphodiesterase. Its characterization and the effect of several hormones on the activity. (1976) (20)
Functional analyses of mammalian protein kinase C isozymes in budding yeast and mammalian fibroblasts (1997) (20)
CYCLIC NUCLEOTIDE PHOSPHODIESTERASE OF HUMAN CEREBROSPINAL FLUID (1975) (20)
Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation. (1986) (20)
Neurocalcin-immunopositive nerve terminals in the muscle spindle, Golgi tendon organ and motor endplate (1998) (20)
Relaxation of vascular smooth muscle by HA-1004, an inhibitor of cyclic nucleotide-dependent protein kinase. (1985) (19)
Beta-migrating very low density lipoprotein attenuates endothelium-dependent relaxation in rabbit atherosclerotic aortas. (1989) (19)
Disorganization by calcium antagonists of actin microfilament in aortic smooth muscle cells. (1987) (19)
Changes of neurocalcin, a calcium-binding protein, in the brain of patients with Alzheimer' s disease (1996) (19)
Antitumor effect of dicyclohexylammonium sulfate, a potent inhibitor of spermidine synthase against P388 leukemia. (1982) (19)
Circumvention of multidrug resistance in P388 murine leukemia cells by a novel inhibitor of cyclic AMP-dependent protein kinase, H-87. (1990) (19)
Overcoming of vinblastine resistance by isoquinolinesulfonamide compounds in adriamycin-resistant leukemia cells. (1992) (19)
KN-62, a calcium/calmodulin-dependent protein kinase II inhibitor, inhibits high potassium-stimulated prolactin secretion and intracellular calcium increases in anterior pituitary cells. (1996) (19)
Calmodulin antagonists enhance calcium binding to calmodulin. (1983) (18)
Selective binding of L-thyroxine by myosin light chain kinase. (1989) (18)
Pharmacological Analysis of Urotensin-induced Contraction and Relaxation in Isolated Rabbit Aortas (1979) (18)
The effects of an intracellular calcium antagonist HA 1077 on delayed cerebral vasospasm in dogs (2005) (18)
Phosphorylation of caldesmon (1989) (18)
Thyroid hormones inhibit the Ca2+ calmodulin-induced activation of myosin light chain kinase. (1988) (18)
Investigation of the pronounced synergism between prostaglandin E2 and other constrictor agents on rat femoral artery. (2006) (18)
Type-specific expression of protein kinase C isozymes in CNS tumor cells (1990) (18)
Blood Pressure Decreased by Halobutylpicolinic Acid, an Inhibitor of Dopamine β-Hydroxylase (1972) (18)
IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. (2014) (18)
Monoclonal antibody recognition of two subtype forms of protein kinase C in human platelets. (1988) (18)
Conformational studies of myosin phosphorylated by protein kinase C. (1985) (18)
2(1H)-quinolinone derivatives as novel anti-arteriostenotic agents showing anti-thrombotic and anti-hyperplastic activities. (1998) (18)
OCCURRENCE OF A SEROTONIN SULPHOTRANSFERASE IN THE BRAIN (1969) (18)
Calcyclin and calvasculin exist in human platelets. (1992) (17)
Inhibitory effects of KN-62, a specific inhibitor of Ca/calmodulin-dependent protein kinase II, on serotonin-evoked Cl− current and 36Cl− efflux in Xenopus oocytes (1991) (17)
Ca2+-independent stimulation of cyclic GMP-dependent protein kinase by calmodulin. (1980) (17)
Selective inhibition of dopamine-beta-hydroxylase in the peripheral tissues by 5-dimethyldithiocarbamylpicolinic acid; its effect on stress-induced ulcer, ethanol-induced sleep and blood pressure. (1974) (17)
Vasodilator effects of C-type natriuretic peptide on cerebral arterioles in rats. (1997) (17)
Specificity of Tetrahymena calmodulin in activation of calmodulin‐regulated enzymes (1982) (17)
Formation of serotonin O-sulfate by sulfotransferase of rabbit liver. (1969) (16)
Demonstration of a Ca2+/calmodulin dependent protein kinase cascade in the hog heart. (1998) (16)
Rho-kinase mediates spinal nitric oxide formation by prostaglandin E2 via EP3 subtype. (2005) (16)
Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes (1995) (16)
Two phosphorylated forms of myosin in thrombin-stimulated platelets. (1988) (16)
Occurrence and distribution of serotonin-O-sulfotransferase in human brain; a new radioisotopic assay. (1972) (16)
Localization of neurocalcin-like immunoreactivity in rat cranial motoneurons and spinal cord interneurons (1995) (16)
Calcium Protein Signaling (2012) (16)
Analogues of fusaric (5-butylpicolinic) acid as potent inhibitors of dopamine -hydroxylase. (1973) (16)
Expression of protein kinase C isozyme in human Langerhans' cells. (1990) (15)
Identification of type III protein kinase C in bovine aortic tissue. (1989) (15)
Capsaicin-sensitive nerves exert an inhibitory effect on the development of fibrin-induced pulmonary edema in rats. (1989) (15)
Molecular cloning of rabbit CAP-50, a calcyclin-associated annexin protein. (1992) (15)
Immunohistochemical evidence for the overexpression of protein kinase C in proliferative diseases of human thyroid. (1991) (15)
Discrepancy of protein kinase C translocation and platelet aggregation--immunocytobiochemical evidence. (1990) (15)
Calcium-independent activation of calcium ion dependent cyclic nucleotide phosphodiesterase by synthetic compounds: quinazolinesulfonamide derivatives. (1983) (15)
Ca2+/calmodulin-dependent protein kinase V: tissue distribution and immunohistochemical localization in rat brain. (1994) (15)
Selective inhibition of cyclic AMP phosphodiesterase from various human tissues by milrinone, a potent cardiac bipyridine. (1988) (14)
Demonstration of intracellular localization of calmodulin antagonist by wet-mounting radioautography. (1983) (14)
Inactivation of serotonin by sulfotransferase system. (1969) (14)
Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers. (1993) (14)
Regional differences in cerebral vasomotor control by nitric oxide (1995) (14)
Inhibition of calmodulin function by CV-159, a novel dihydropyridine compound. (1988) (14)
Inhibitory effects of KN-93, an inhibitor of Ca2+ calmodulin-dependent protein kinase II, on light-regulated root gravitropism in maize. (1993) (14)
A newly synthesized bifunctional inhibitor, W-77, enhances adriamycin activity against human ovarian carcinoma cells. (1993) (13)
Obviation of drug resistance and affinity purification of P-glycoprotein by isoquinolinesulfonamides. (1991) (13)
Formation of serotonin O-sulfate by rat liver sulfating system. (1966) (13)
Effect of Acetylcholine on the Norepinephrine‐Induced Positive Chronotropy and Increase in Cyclic Nucleotides of Isolated Rabbit Sinoatrial Node (1979) (13)
Gamma-aminobutyric acid-induced contraction of the dog basilar artery. (1984) (13)
[Signal-transduction therapy]. (1995) (13)
Neurocalcin-like immunoreactivity in the rat esophageal nervous system (1998) (13)
Studies on chemical modification of monensin. VI. Preparation of C-7 modified monensins via protected 7-oxomonensin and evaluation of their ion transport activity. (1997) (13)
Effects of coriolan, an antitumor polysaccharide, produced by Coriolus versicolor Iwade. (1980) (13)
3':5'-cyclic-nucleotide phosphodiesterases of mammalian sera. (1975) (13)
Assay of S-100 protein by an enzyme immunoassay method. (1983) (13)
Fusaric (5-butylpicolinic) acid: its effect on plasma growth hormone. (1973) (13)
Cascade activation of the calmodulin kinase family. (1997) (13)
Neurocalcin-α immunoreactivity in the enteric nervous system of young and aged rats (2002) (13)
Effect of the 1-methyl-4-phenylpyridinium ion on phosphorylation of tyrosine hydroxylase in rat pheochromocytoma PC12h cells (1988) (13)
IMMUNOHISTOCHEMICAL LOCALIZATION OF PROTEIN KINASE C ISOZYMES IN HUMAN CEREBELLUM, HIPPOCAMPUS AND SPINAL CORD (1991) (12)
Efficient synthesis of [11C]H-1152, a PET probe specific for Rho-kinases, highly potential targets in diagnostic medicine and drug development ☆ (2012) (12)
Possible prophylactic potential of HA1077, a Ca2+ channel antagonist and vasodilator, on chronic cerebral vasospasm. (1992) (12)
Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes. (1998) (12)
Casein kinases I and II from squid brain exhibit selective neurofilament phosphorylation (1992) (12)
Stimulation of human platelet guanylate cyclase by nitroso compounds. (1982) (12)
CHAPTER 2 – Modulation of Ca2+-Dependent Regulatory Systems by Calmodulin Antagonists and Other Agents (1985) (12)
A Ca2+‐sensitive actin regulatory protein from smooth muscle (1985) (12)
Neuronal nitric oxide synthase-membrane phospholipid interactions. (1998) (12)
Increase in S-100b protein content in thyroid carcinoma. (1987) (12)
Immunohistochemical localization of neurocalcin in human sensory neurons and mechanoreceptors (2000) (12)
Inhibition of dopamine beta-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo. (1970) (11)
Protein kinase inhibitors. (1994) (11)
Structural characterization of the calcium binding protein s100 from adipose tissue. (1985) (11)
Intracellular Localization of Calmodulin Antagonist (W-7) (1982) (11)
Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla (1997) (11)
Neurocalcin-immunoreactive primary sensory neurons in the trigeminal ganglion provide myelinated innervation to the tooth pulp and periodontal ligament (2000) (11)
Hydrophobic properties of Tetrahymena calmodulin related to the phosphodiesterase activity (1983) (11)
Relaxant effects of various xanthine derivatives. Relationship to cyclic nucleotide phosphodiesterase inhibition. (1992) (11)
Roles of intracellular Ca2+ receptors in the pancreatic β-cell in insulin secretion (2004) (11)
Changes in cyclic nucleotide phosphodiesterase activity and calmodulin concentration in heart muscle of cardiomyopathic hamsters. (2004) (11)
Novel and selective inhibitors of CaM-kinase II and other calmodulin-dependent enzymes. (1990) (10)
Regulation of preimplantation development of mouse embryos: effects of inhibition of myosin light-chain kinase, a Ca2+/calmodulin-dependent enzyme. (1996) (10)
A role of nitric oxide in vasomotor control of cerebral parenchymal arterioles in rats. (1994) (10)
Carbachol‐induced contraction in the circular muscle of guinea‐pig stomach in calcium‐free solution (1986) (10)
Alterations in pharmacological receptor activities of rabbit arteries by sulfhydryl reagents. (1983) (10)
Effects of CDP-choline on striatal dopamine level and behavior in rats. (1981) (10)
[Inhibitor of calmodulin and calmodulin dependent enzyme]. (1998) (10)
Identification of a 80 kDa calmodulin-binding protein as a new Ca2+/calmodulin-dependent kinase by renaturation blotting assay (RBA). (1992) (10)
Molecular pharmacology of protein kinases (1990) (10)
Oxyhemoglobin enhancement of vasopressin-induced constriction in rat cerebral arterioles. (1994) (10)
Alteration of norepinephrine release from [3h]-norepinephrine preloaded basilar artery by naphthalenesulfonamides. (1982) (10)
Phospholipids and regulation of protein kinase reaction. (1981) (10)
HMN-1180, a small molecule inhibitor of neuronal nitric oxide synthase. (1998) (9)
Purification and characterization of a novel protein activator of Ca2+/calmodulin-dependent protein kinase I. (1995) (9)
A rapid and simple assay of serotonin sulfokinase activity. (1967) (9)
Cyclic 3':5'-nucleotide phosphodiesterase of rabbit sinoatrial node. (1978) (9)
Effect of calmodulin inhibitors on thyroid hormone secretion. (1986) (9)
Different sensitivities of Ca2+, calmodulin-dependent cyclic nucleotide phosphodiesterases from rabbit aorta and brain to dihydropyridine calcium channel blockers. (1987) (9)
Relaxation of isolated rabbit arteries by fusaric (5-butylpicolinic) acid. (1976) (9)
Modulation of tyrosine kinase activity has multiple actions on insulin release from the pancreatic beta-cell: studies with lavendustin A. (1997) (9)
Monoclonal antibody assessment of tissue- and species-specific myosin light chain kinase isozymes. (1989) (8)
Roles of intracellular Ca 2+ receptors in the pancreatic β-cell in insulin secretion (1999) (8)
Purification and characterization of calcium-calmodulin kinase II from human parathyroid glands. (1991) (8)
Studies on human iodide peroxidase: its activity in various thyroid disorders. (1975) (8)
Selective inhibitors of calmodulin-dependent phosphodiesterase and other enzymes. (1988) (8)
Calcium-dependent interactions of an ionophore A23187 with calmodulin. (1985) (8)
Alteration of human platelet protein kinase C with normal aging (1993) (8)
A new system to detect native microaggregates of platelets in vivo, with a novel platelet aggregometer employing laser light scattering. (1998) (8)
A novel Ca2+/calmodulin-dependent protein kinase lacking autophosphorylation activity in the rabbit heart. (1995) (8)
Micro-determination of monoamine oxidase using serotonin as substrate. (1967) (8)
Neurocalcin-alpha immunoreactivity in the enteric nervous system of young and aged rats. (2002) (8)
Platelet Aggregation and Cyclic Nucleotide Phosphodiesterase Activity in Arteriosclerotic Patients (1978) (8)
S-100 antigen and calmodulin in human leukemic cells. (1989) (8)
Calcium-dependent interactions with calmodulin of a fluorescent calmodulin antagonist: N2-dansyl-L-arginine-4-t-butylpiperidine amide. (1983) (8)
3':5'-cyclic-nucleotide phosphodiesterase in the bovine pituitary gland. (1983) (8)
Enhancement of antibody-independent phagocytosis by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7). (1983) (7)
Ca2+/calmodulin-dependent protein kinase V and I may form a family of isoforms. (1994) (7)
Possible involvement of protein kinase C in compaction of preimplantation mouse embryos (1989) (7)
K-134, a Phosphodiesterase 3 Inhibitor, Prevents Brain Damage by Inhibiting Thrombus Formation in a Rat Cerebral Infarction Model (2012) (7)
Ca2+-dependent cyclic nucleotide phosphodiesterase is activated by poly(L-aspartic acid). (1985) (7)
Annexin XI may be involved in Ca2+ - or GTP-gammaS-induced insulin secretion in the pancreatic beta-cell. (2000) (7)
A new and potent calmodulin antagonist, HF-2035, which inhibits vascular relaxation induced by nitric oxide synthase. (1996) (7)
POTENTIATION OF THE CONTRACTILE RESPONSE TO ACETYLCHOLINE IN AORTIC STRIPS BY LOW CONCENTRATIONS OF VASCULAR CONTRACTILE AGONISTS (1980) (7)
Decreased neurocalcin immunoreactivity in sympathetic and parasympathetic neurons of the major pelvic ganglion in aged rats (2001) (7)
Ca(2+)-independent, phospholipid-activated protein kinase in 3Y1 cells. (1991) (7)
Identification of two subtypes of protein kinase C in human placenta. (1991) (7)
CHAPTER 33 – Calmodulin Antagonists and Protein Kinase C (1985) (7)
INHIBITION OF DOPAMINE β-HYDROXYLASE IN BLOOD VESSELS BY PICOLINIC ACID DERIVATIVES IN VIVO AND THEIR ANTIHYPERTENSIVE EFFECTS (1975) (7)
Effect of KN-62, Ca2+/calmodulin-dependent protein kinase II inhibitor, on adriamycin resistance of human ovarian cancer cells. (1995) (6)
Isoform-specific intracellular vesicle formation by recombinant annexin XI-A in Sf9 cells. (1996) (6)
Multidrug resistance in Yoshida rat ascites hepatoma cell lines. (1992) (6)
Effect of unsaturated fatty acids on separated form of human platelet cyclic nucleotide phosphodiesterase. (1978) (6)
Thrombin-induced shape change in human megakaryoblastic leukemic cells, MEG-01, is mediated by protein kinase C. (1992) (6)
A fluorescent protein kinase C inhibitor: 1-(1-hydroxy-5-isoquinolinylsulfonyl)piperazine. (1988) (6)
Molecular pharmacology of calcium, calmodulin-dependent myosin phosphorylation in vascular smooth muscle. (1990) (6)
EFFECT OF ANTI‐THYROID AGENTS, METHIMAZOLE AND PROPYLTHIOURACIL, ON BRAIN NORADRENALINE CONTENT (1977) (6)
Calcyclin, a calcium-binding protein, which regulates insulin secretion from the permeabilized pancreatic beta-cell. (1997) (6)
Purification, characterization, and partial sequence analysis of 32-kDa calcimedin from chicken gizzard. (1990) (6)
Cyclic 3',5'-nucleotide phosphodiesterase activities in the thyroid glands of patients with various disorders. (1980) (6)
Inhibition of thyroid iodide peroxidase in vivo and in vitro by iproniazid. (1970) (6)
Neuronal nitric oxide synthase specific autophosphorylation in baculovirus/Sf9 insect cell system. (1996) (5)
Regional distribution of dopamine and norepinephrine in canine cerebral arteries — effect of pre- or postganglionic sympathetic denervation (1983) (5)
Ca2+/calmodulin-dependent protein phosphorylation associated with the cytoskeleton of quiescent rat fibroblast (3Y1) cells. (1991) (5)
Immunocytochemical detection and spatial distribution of myosin light-chain kinase in preimplantation mouse embryos. (1997) (5)
Protective effects of the calmodulin antagonist bepridil on ischaemia induced in the rat myocardium. (1986) (5)
Search for the functional substrate proteins of protein kinases and their selective inhibitors. (1990) (5)
PICOLINIC ACID DERIVATIVES AS INHIBITORS OF DOPAMINE β-HYDROXYLASE IN VIVO; THEIR EFFECTS ON BLOOD PRESSURE AND STRESS ULCER (1973) (5)
Thrombin-induced translocation of protein kinase C in human megakaryoblastic leukemia cells (MEG-01). (1991) (5)
Calmodulin and acidic compounds alter basic protein phosphorylation by the protein kinase from human platelets. (1982) (5)
Serum cyclic 3',5'-nucleotide phosphodiesterase in patients with various thyroid disorders. (1985) (5)
Selective low level of protein kinase C isozyme in a tumor promoter-dependent mouse leukemia cell line. (1989) (5)
Involvement of calmodulin and calmodulin binding site in the TSH receptor of thyroid. (1987) (5)
Calcium-Dependent Regulation of Interactions of Caldesmon with Calcium-Binding Proteins Found in Growth Cones of Chick Forebrain Neurons (2001) (5)
[Molecular pharmacology on protein kinase C]. (1986) (5)
Purification and characterization of 81K, heat stable calmodulin-binding protein from bovine brain. (1989) (5)
Hydrophobic regions of calcium binding proteins (1984) (5)
Biopharmacological Regulation of Protein Phosphorylation (1987) (5)
Mepacrine-induced inhibition of human platelet cyclic-GMP phosphodiesterase. (1984) (5)
The effects of HA1077 on the cerebral circulation after subarachnoid haemorrhage in dogs (2005) (5)
Evidence for posttranscriptional regulation of transgenic protein kinase C–alpha in T cells (1994) (4)
Potentiation in various agonists-induced contractions of rabbit mesenteric artery by sulfhydryl reagents. (1983) (4)
HMN-709, a chlorobenzenesulfonamide derivative, is a new membrane-permeable calmodulin antagonist. (1996) (4)
A novel isoquinoline sulfonamide protein kinase inhibitor (H-1337) produces long-lasting reduction of IOP (2015) (4)
Interaction of calcium-binding proteins with calmodulin-dependent guanylate cyclase in Tetrahymena plasma membrane. (1985) (4)
Investigation of binding proteins for anti-platelet agent K-134 by Drug-Western method. (2007) (4)
Contraction of smooth muscle in Ca-free solution. (1985) (4)
CHAPTER 32 – Interaction of W-7, a Calmodulin Antagonist, with Another Ca2+-Binding Protein (1985) (4)
Identification of Ca2+/calmodulin-dependent protein kinase and endogenous substrate of Fusarium oxysporum. (1992) (4)
IMMUNOHISTOCHEMICAL LOCALIZATION OF PROTEIN KINASE C ISOZYMES (1992) (4)
Inhibition of human platelet secretion and of Ca2+, calmodulin-dependent protein phosphorylation by the antiallergic agent GMCHA. (1988) (4)
KN‐62: A Specific Ca2+/calmodulin‐dependent Protein Kinase Inhibitor as a Putative Function‐searching Probe for Intracellular Signal Transduction (1996) (4)
TIME0URSE CHANGES IN BLOOD PRESSURE, URINARY EXCRETION OF NOREPINEPHRINE AND DOPAMINE AFTER ADMINISTRATION OF FUSARIC ACID IN A SINGLE DOSE IN ELDERLY HYPERTENSIVE PATIENTS (1976) (4)
Acidic calmodulin binding protein, ACAMP-81, is MARCKS protein interacting with synapsin I. (1992) (4)
Inter-isoformal regulation of nitric oxide synthase through heteromeric dimerization. (1998) (4)
Calmodulin regulation during the cell cycle of mammalian cells. (1981) (4)
Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy (2005) (4)
The signal transduction systems and intracellular Ca2+ dynamics in arachidonate-induced platelet activation. (1989) (4)
Effect of the intracellular calcium antagonist HA1004 on cerebral blood flow in rats. (1988) (4)
Contractile responses of mammalian cerebral arteries to 15-hydroperoxyarachidonic acid vary in the presence of fusaric acid and verapamil. (1984) (4)
Prevention of intimal proliferation by cilostamide (1994) (4)
Neurocalcin‐immunoreactive neurons in the mammalian dorsal root ganglia, including humans (2000) (3)
HIGH ACTIVITY OF CYCLIC 3′,5′‐NUCLEOTIDE PHOSPHODIESTERASE IN SERA OF PATIENT WITH PHAEOCHROMOCYTOMA (1986) (3)
[Modifiers of calcium action]. (1993) (3)
Phosphorylation of bovine brain 81-kDa acidic calmodulin binding protein (ACAMP-81) in vitro. (1991) (3)
a calmodulin antagonist, inhibits cell proliferation (3)
Inhibition of thyroid iodide peroxidase by hydrazines and NSD-1055 (4-bromo-3-hydroxybenzyl-oxyamine). (1971) (3)
Effect of cholera enterotoxin on pacemaker rate and cyclic adenosine 3':5'-monophosphate in isolated rabbit sinoatrial node. (1979) (3)
Immunocytochemical detection of Ca2+-dependent subspecies of protein kinase C in mouse embryos before and during compaction (1994) (3)
The effects of an anti‐atherosclerotic drug, pyridinolcarbamate, on heart, vascular and brain biogenic amines (1973) (3)
The localization of a new antithrombotic agent, cilostazol, in CHO-K1 cells as demonstrated by autoradiography. (1985) (3)
Inhibition of P-glycoprotein-dependent multidrug resistance by an isoquinolinesulfonamide compound H-87 in rat ascites hepatoma AH66 cells. (1996) (3)
Plasma dopamine-beta-hydroxylase activity and thyroid suppressibility in Graves' disease. (1979) (3)
A calcium-binding protein from rabbit lung cytosol identified as the product of growth-regulated gene (2A9) and its binding proteins. (1991) (3)
Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C. (1988) (3)
New pharmacological strategies in vascular diseases: a novel intracellular calcium antagonist, HA1077 (AT-877) and cerebral vasospasm. (1990) (3)
RELAXATION OF ISOLATED AORTA OF THE RABBIT BY PICOLINIC ACIDS (1977) (3)
KN-62, l-[N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-~-tyrosyl]-4- phenylpiperazine, a Specific Inhibitor of Ca2”/Calmodulin-dependent Protein Kinase II* (2001) (3)
Myosin light-chain phosphorylation controls insulin secretion at a proximal step in the secretory cascade. (1997) (3)
90-kDa S6 kinase is insufficient or not involved in the activation of glycogen synthase induced by insulin. (1996) (3)
Serum cyclic 3',5'-nucleotide phosphodiesterase activity in myocardial infarction. (1985) (3)
THE THREE-DIMENSIONAL STRUCTURE OF CA2+-BOUND CALCYCLIN: IMPLICATIONS FOR CA2+-SIGNAL TRANSDUCTION BY S100 PROTEINS, NMR, 20 STRUCTURES (1999) (3)
Calcium-Dependent Functional Hydrophobic Regions of Calcium-Modulated Proteins (1987) (2)
Urinary norepinephrine excretion in elderly hypertensive patients during administration of fusaric acid. (1976) (2)
[Effect of vinpocetine (TCV-3B), a vasodilator agent, on cyclic nucleotide metabolism]. (1982) (2)
Intracellular signaling by protein kinase C (1989) (2)
Roles of calcium in the regulation of tyrosine hydroxylase. (1989) (2)
[Annexin family]. (1998) (2)
Effect of beta-adrenergic blockade on plasma dopamine-beta-hydroxylase activity and triiodothyronine in hyperthyroidism. (1980) (2)
Elucidation of molecular mechanism of H-1337, an anti-glaucoma agent (2015) (2)
[Platelet cyclic nucleotides and calcium]. (1979) (2)
Cyclic AMP phosphodiesterase from human heart and drug action. (1992) (2)
Specific inhibition of 40 K protein phosphorylation in platelet by a new antithrombotic agent, d-indobufen. (1989) (2)
A newly synthesized bifunctional inhibitor, CKA1083, enhances adriamycin activity against human ovarian carcinoma cells. (1997) (2)
Pharmacology of calmodulin and kinase C antagonists. (1986) (2)
Clinical and pathological significance of sibling Graves' disease. (1980) (2)
Biopharmacological assessment of calmodulin function: utility of calmodulin antagonist naphthalenesulfonamide. (1981) (2)
Identification and characterization of protein kinase C-related enzymes in frog retina. (1991) (2)
Inhibition of the G1/S transition in A65 cells by H-7, a protein kinase C inhibitor. (1993) (2)
H-1129 suppresses neovascularization through inhibition of secretion of VEGF and proliferation of vascular endothelial cells (2017) (2)
CHAPTER 6 – Effects of Calmodulin Antagonists on Cell Proliferation (1985) (2)
Role of protein phosphorylation in Ca2+ regulated intracellular messenger systems. (1989) (2)
Intracellular Signal Transduction and Cell Function. (1996) (2)
Identification of two subtypes of protein kinase C in human placenta (1992) (2)
Molecular Pharmacology of Myosin Light Chain Phosphorylation of Smooth Muscle and Nonmuscle Cells (1987) (2)
Ca2+, phospholipid and Ca2+, calmodulin-dependent myosin light chain phosphorylation of smooth muscle and nonmuscle cells. (1988) (2)
PURIFICATION AND PARTIAL AMINO ACID SEQUENCE OF CALMODULIN FROM FUSARIUM OXYSPORUM (1994) (1)
Subject Index, Vol. 36, 1988 (1988) (1)
Effect of somatostatin and dopaminergic agents on bovine pituitary phosphodiesterase activity. (1986) (1)
Ca2(+)-dependent protein kinase cascade of platelets. (1989) (1)
Reverse relationship between malignancy and cyclic AMP-dependent protein kinase activity in Yoshida rat ascites hepatomas. (1993) (1)
Unique inhibitory action of the synthetic compound 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)] amino-N-(4-chlorocinnamyl)-N-methylbenzylamine (CKA-1306) against calcium/calmodulin-dependent protein kinase I. (1998) (1)
Phorbol esters potentiate glucocorticoid-induced cytotoxicity in CEM-C7 human T-leukemia cell line. (1988) (1)
Contents, Vol. 53, 1992 (2004) (1)
Inhibitors of Protein Kinases and Protein Phosphates Contributors (2005) (1)
Isoquinoline sulfonamides such as fasudil, H-1152, ripasudil and H-1129 produce IOP-lowering and neuroprotective effects through Rho kinase inhibition (2018) (1)
Protein kinase C and platelets. (1985) (1)
Inhibitory effect of thyroid hormones on pituitary cyclic AMP phosphodiesterase activity in vitro (1984) (1)
EFFECT OF DOPAMINE-β-HYDROXYLASE INHIBITOR ON STRESS-INDUCED GASTRIC ULCER (1976) (1)
Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions (1988) (1)
[Trend in the development of new inhibitors of cyclic nucleotide metabolism and their clinical application]. (1991) (1)
[Intracellular calcium signaling and selective inhibitors]. (1988) (1)
Identification and purification of Ca2+/calmodulin-dependent protein kinase V from human gastric carcinoma. (1996) (1)
Alpha1-adrenergic stimulation induced hypertrophy in protein kinase C down-regulated cultured cardiac myocytes. (1999) (1)
d-Indobufen inhibits collagen-induced intracellular calcium mobilization and inositol phosphates formation in human platelets. (1990) (1)
CHAPTER 25 – Elucidation of Regulatory Mechanism of Tyrosine Hydroxylase and Tryptophan Hydroxylase by Calmodulin Antagonists (1985) (1)
The role of Ca2+-dependent protein phosphorylation in platelet aggregation (1980) (1)
Calcium signaling of calcium-binding proteins and drug actions. (1989) (1)
[Pharmacology on calmodulin: calmodulin antagonist]. (1982) (1)
Ca2+-channel blockers and calmodulin (1983) (1)
Increase of vinblastine accumulation by inhibitors of calmodulin-dependent cell functions in rat ascites hepatoma AH66 cells. (1992) (1)
Platelet aggregation and protein phosphorylation. (1980) (1)
2(1H)-Quinolinone Derivatives as Novel Antiarteriostenotic Agents Showing Antithrombotic and Antihyperplastic Activities. (1998) (1)
Molecular pharmacology of protein kinase C. (1989) (1)
[Beta-adrenergic modulation of cardiac Na+ current]. (1992) (1)
S-1 O 0 protein and calmodulin levels in cerebrospinal fluid after subarachnoid hemorrhage (2009) (0)
Molecular Regulation of Calcium, Calmodulin-Dependent Myosin Phosphorylation (1988) (0)
Studies on cardiac ingredients of plants. XIII: Chemical modification of gitoxin to cardiotonic compounds without vascular effect. (1997) (0)
Studies on antitumor activity of Ba s idiomycete polysaccharide (Report 29): Antitumor effect and biological activity of Agaricus heterosistes Heinem et Goss (1981) (0)
The Catalytic Subunit of cAMP-dependent Protein Kinase in Complex with Rho-kinase Inhibitor Fasudil (HA-1077) (2003) (0)
Aminostilbazolderivat and drug (1995) (0)
EFFECTOFANTI-THYROID AGENTS,METHIMAZOLEAND PROPYL- THIOURACIL, ON BRAINNORADRENALINECONTENT (1977) (0)
A globular structure of calcium-bound calmodulin-W-7 complex in solution (1998) (0)
Future prospective of phosphodiesterase-3 inhibitors as antithorombotic drug (2011) (0)
[Calcium protein signaling]. (1989) (0)
Effect of cyclic AMP and cyclic GMP phosphodiesterase on platelet aggregation (1977) (0)
Nuclear localization of annexin XI, a novel annexin (1994) (0)
Activation of Ca2+-dependent cyclic nucleotide phospho diesterase by poly-L-aspartic acid and inhibition by calmodu lin antagonsits (1984) (0)
Effect of myosin light-chain kinase inhibition on premature compaction of preimplantation mouse embryos : Papers Presented from Platform (1996) (0)
[Molecular pharmacologic approach to cell-communication transduction]. (1989) (0)
Various Types of Human Leukemic Cells Expression of Three Major Protein Kinase C Isozymes in Updated (2006) (0)
Platelet strip and vascular contraction - A model of study on platelet and vascular interaction (1982) (0)
Neurocalcin; its un unique expression and a possible role in the Ca2+-signal transduction system in the neural cells (1994) (0)
[Biochemical mechanism of blood platelet release reaction, aggregation and adhesiveness]. (1978) (0)
A method for determining the gene of a target protein with the aid of a medicament (1998) (0)
[Non-steroidal anti-inflammatory drugs. Suppression of biological response and non-steroidal anti-inflammatory drugs]. (1987) (0)
Immunohistochemical demonstration of protein kinase C isozymes in mouse oocytes and preimplantation embryos : Abstracts of Papers Presented at the Thirtieth Annual Meeting of the Japanese Teratology Society Miyazaki, Japan, July 12-13, 1990 (1990) (0)
Contributions of cyclic nucleotides in the genesis of chronotropism in isolated rabbit sinoatrial node (1977) (0)
Development of inhibitors of protein kinases and their clinical application (1998) (0)
THE STRUCTURE OF CALCYCLIN REVEALS A NOVEL HOMODIMERIC FOLD FOR S100 CA2+-BINDING PROTEINS, NMR, 22 STRUCTURES (1996) (0)
Immunoaffinity purification of type I protein kinase C. (1990) (0)
The heterogeneity in calmodulin antagonists’ binding sites (1986) (0)
A method for determination of the assets of a target proteins with the help of a medication with (1998) (0)
Platelet function and Ca2+-calmodulin-dependent protein phosphorylation (1982) (0)
Isoquinoline and drug (1997) (0)
-111-β VERY LOW DENSITY LIPOPROTEIN ATTENUATES ENDOTHELIUM DEPENDENT RELAXATION IN RABBIT ATHEROSCLEROTIC VESSELS : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1989) (0)
Isoquinoline derivatives and pharmaceutical (1997) (0)
-1382- The effect of estrogen on neuronal and endothelial constitutive nitric oxide synthase(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY) (1995) (0)
Inhibition of dopamine beta-hydroxylase in blood vessels by picolinic acid derivatives in vivo and their anthypertensive effects. (1975) (0)
Time-Course Changes in Blood Pressure,Urinary Excretion of Norepinephrine and Dopamine After Administration Elderly Hypertensive Patients (1977) (0)
Signal Transduction Therapy (1996) (0)
Effects of lysine-naphthalene sulfonamide derivatives on the thrombin induced human platelet aggregation and the release reaction (1981) (0)
Demonstration of Small Molecular Compound ^3H-W-7 by Means of Light Microscopic Radioautography (1982) (0)
The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 (2003) (0)
Ca2+ mobilization controls granule movement of insulin granules (1997) (0)
Effects of the stereoisomers of antipsychotic agents on rabbit aortic strips (1982) (0)
228. Cyclic 3':5' Nucleotide Phosphodiesterase and Calcium-regulated Protein Modulator (Calmodulin) in Human Placenta (1979) (0)
Co-Expression of iNOS and nNOS in COS-7 Cells and Its Effect on Apoptosis Induced by Serum Deprivation (1997) (0)
IS PROTEIN KINASE C(PKC)ACTIVATION ESSENTIAL FOR THE HYPERTROPHIC EFFECT OF α_1-ADRENERGIC STIMULATION? (1993) (0)
Protein kinase A controls movement of secretory granules in the pancreatic β-cell. (1996) (0)
Newly Synthesized Potent ROCKII Inhibitor Isoquinolinesulfonamide Derivative Remarkably Reduces Intraocular Pressure in Cynomologus Monkey and Rabbit (2008) (0)
Detection of modified β2-microglobulin (β2m) from amyloid deposits in tenosynovial tissue of carpal tunnel syndrome (CTS) (1994) (0)
LDL Impairs Endothelium-Dependent Relaxation especially in Hyperlipidemic Porcine Coronary Arteries (1990) (0)
Cyclic AMP in Leukemic Cell Lysate in Disseminated Intravascular Coagulation (1992) (0)
PKC induces RhoA activation followed by phosphorylation of MARCKS and MBS in neuroblastoma SH‐SY5Y cells. (2006) (0)
IDENTIFICATION OF AUTOINHIBITORY AND CALMODULIN-RINDING DOMAINS ON CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE I (1995) (0)
A newly synthesized selective casein kinase I inhibitor, CK1-7, and affinity purification casein kinase I from bovine testis (1989) (0)
Effects of myosin light-chain kinase inhibition on the organization of acto-myosin cytoskeleton during preimplantation mouse development : The 35th Annual Meeting of the Japanese Teratology Society (1995) (0)
Effect of a naphthalenesulfonamide derivative on isolated rabbit blood vessels (1977) (0)
80 – IROLE OF Ca2+-REGULATED ACTIVATOR PROTEIN OF CYCLIC NUCLEOTIDE PHOSPHODIESTERASE IN VASCULAR SMOOTH MUSCLE ACTOMYOSIN SUPERPRECIPITATION (1978) (0)
Procede de detection in vivo d'un gene proteique cible a l'aide de medicament (1998) (0)
Ca2+ regulation in chicken gizzard and bovine aorta actomyosin (1980) (0)
[Calmodulin dependent regulation of smooth muscle contraction]. (1990) (0)
Molecular pharmacology of protein phosphorylation in the cell functions. (1993) (0)
BINDING OF BEPRIDIL, A CALCIUM CHANNEL BLOCKER, TO CALMODULIN : Antianginal Drugs : FREE COMMUNICATIONS (V) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1985) (0)
Purification, characterization and cDNA cloning of calcyclin-associated protein (CAP-50) (1992) (0)
[Molecular structure and function of platelet calcium binding protein]. (1987) (0)
TSH-binding inhibitor IgG in some sera from Hashimoto ' s (2010) (0)
[Ca2+-dependent phosphorylation of cytoskeleton proteins and its pharmacological control]. (1989) (0)
260. Immunological Studies on the Human Fetal-Maternal Interaction : (1980) (0)
[Pharmacology of calmodulin : calmodulin antagonist (author's transl)]. (1981) (0)
β-adrenergic modulation of cardiac Na + current : Mechanism of intracellular regulation of cardiac ion channels and its abnormality (1993) (0)
Development of molecular probes for the research of calmodulin-dependent enzymes. (1992) (0)
Direct inhibition of myosin light chain kinase by naphthalenesulfonamide derivatives (1985) (0)
[Blood platelets and cyclic nucleotide metabolism]. (1979) (0)
Hsp90-binding Compound, H-1129, Produces IOP Lowering And Fibronectin Reduction (2012) (0)
Oligomerization of Nitric Oxide Synthase (NOS) : Interisoformal Structure-activity Analyses of NOS (1996) (0)
2.P.336 Native microaggregates and spontaneous platelet aggregation may present a platelet susceptibility leading to thrombogenesis - detection with an original method using a novel platelet aggregometer employing a laser light scattering (1997) (0)
How does glucose activate intracellular movement of the insulin granules (1999) (0)
118. Metabolic Significance of Cyclic Nucleotides in the Environment for the Gorwth of Fetus (The Third Reptort) : Particularly, the Movement of Cyclic Nucleotide Phosphodiesterase in Serum of Pregnant Woman (1980) (0)
Aminostilbazolderivate and medical (1995) (0)
[Enzymatic O-sulfation of serotonin]. (1968) (0)
Characteristics of antibodies to calmodulin in patients with Graves' disease. (1987) (0)
Enhancement of antibody-independent phagocytosis by a calmodulin antagonist. (1983) (0)
Phosphorylation of myosin light chain by Ca2+-activated, phospho-lipid-dependent protein kinase in smooth muscle (1983) (0)
Two types of calmodulin antagonists: A structurally related interaction (1983) (0)
Effects of Molsidomine and its metabolites on human platelet aggregation and guanylate cyclase activity (1981) (0)
225. Metabolic Significance of C-AMP, C-GMP in the Environment for the Growth of Fetus, (the Second Report) : Particularly, Localization of these Nucleotides in Human Placental Tissue and Changes of Phosphodiesterase Activity (1979) (0)
Novel and specific Rho-kinase inhibitor, H1152P, directed against the Rho-kinase involved pathway (2001) (0)
Development of specific Rho-kinase inhibitor and its clinical application (2005) (0)
[Experimental study on the efficacy of the combined use of Young's solution in myocardial protection by asanguinous cardioplegia]. (1983) (0)
[Enzyme inhibitors--current status and future scope]. (1991) (0)
Proceedings: Inhibition of platelet cyclic AMP phosphodiesterase and platelet aggregation. (1974) (0)
-1132-LDL IMPAIRS ENDOTHELIUM-DEPENDENT RELAXATION ESPECIALLY IN HYPERLIPIDEMIC PORCINE CORONARY ARTERIES : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY (1990) (0)
Proceedings: In vivo inhibition of dopamine beta-hydroxylase and blood pressure. (1974) (0)
A novel dihydropyrldine Ca2+ antagonist, CV159: Biopharmacological properties different from those of nicardipine (1986) (0)
-0627-THE ROLE OF CALMODULIN IN THE REGULATION OF GAP JUMCTIONAL CONDUCTANCE BETWEEN CARDIAC CELLS (1990) (0)
Quantitative radioautographic study of intracellular localization of calmodulin antagonist, W-7, in Chinese-hamster ovary cells (2004) (0)
Chelation of copper reduces inhibition by oxidized lipoproteins of endothelium-dependent relaxation in porcine coronary arteries (2005) (0)
Effects of Ca2+/CaM kinase II inhibitor (KN-62) on the phosphorylation of the cytoskeletal element in cultured cells. (1991) (0)
Contents, Vol. 36, 1988 (1984) (0)
a! 1-ADRENERGIC STIMULATION INDUCED HYPERTROPHY IN PROTEIN KINASE C DOWN-REGULATED CULTURED CARDIAC (1999) (0)
EFFECTS OF UROPHYSIAL EXTRACTS ON THE CARDIOVASCULAR SYSTEM OF THE CARP, Cyprinus carpio (1983) (0)
Therapeutic potential of a novel isoquinoline sulfonamide derivative with protein kinase inhibition function, H-1337, in wet AMD (2015) (0)
Discovery and development of pharmacological probes for protein kinases (1992) (0)
COMPRISING ATPMMETCS CONUGATED TO PEPTDES OR PEPTIDOMIMETCS (2017) (0)
151 Indentification of two subtype forms of protein kinase C in human placenta. (1990) (0)
Intracellular Localization of the Calmodulin Antagonist (1982) (0)
Role of Phosphodiesterase III in the Control of Blood Flow (1996) (0)
Distribution of A23187 in cloned rabbit aortic smooth muscle celles (1984) (0)
Purification and characterization of Ca2+·phospholipid dependent protein kinase (C kinase) from human platelets (1985) (0)
.omega.-(ARYLSULFAMIDE)-ALKYLAMINE (1975) (0)
THE NOVEL CALMODULIN ANTAGONIST HMN-709B (1995) (0)
Anti-gizzard MLCK monoclonal antibody MM13 inhibits superprecipitation and phosphorylation of bovine aortic smooth muscle actomyosin. (1989) (0)
[Experimental study on the effects of compositions of cardioplegic solutions on coronary arteries]. (1984) (0)
Proceedings: Effect of fusaric acid and its derivatives on ethanol induced sleep of mice, stress induced gastric ulcer and blood pressure of rats. (1974) (0)
Effect of hypophysectomy on cyclic 3',5'-nucleotidemetabolizing enzymes in the rat thyroid gland. (1985) (0)
Factor NF-Y Multidrug-Resistant Cells by Targeting the Transcription Agent HMN-214 , Restores Chemosensitivity to HMN-176 , an Active Metabolite of the Synthetic Antitumor (2003) (0)
Studies on Cardiac Ingredients of Plants. XIII : Chemical Modification of Gitoxin to Cardiotonic Compounds without Vascular Contractile Effect (1997) (0)
Elucidation of the intracellular signal transduction by synthesized compounds (1997) (0)
Purification of 81K protein, a new calmodulin binding protein from bovine brain (1990) (0)
Selective inhibitor of platelet cAMP phosphodiesterase, cilostamide, inhibits platelet aggregation (1980) (0)
Calmodulin interacting agents. (1980) (0)
CONTRIBUTION OF CYCLIC AMP IN THE DELAYED EFFECT OF NORADRENALINE ON CHRONOTROPISM OF SINOATRIAL NODE WITH SIMULTANEOUS APPLICATION OF NORADRENALINE AND ACETYLCHOLINE (1979) (0)
[Molecular pharmacology of intracellular calcium signaling]. (1990) (0)
1472 – EFFECTS OF A NOVEL MARINE POLYPEPTIDE, GONIOPORA TOXIN, ON ELECTROMECHANICAL PROPERTIES OF RABBIT MYOCARDIUM (1978) (0)
Effect of 8-substituted cyclic AMP derivatives on soluble guanylate cyclase activity from human platelets. (1981) (0)
News omega- (arylsulfonamido) alkylamine, their process for the preparation and application in therapeutic (1975) (0)
Inhibition of dopamine beta-hydroxylase by anti-thyroid agents, methimazole and propylthiouracil. (1977) (0)
Calvasculin, a new member of the EF-hand protein purified by a newly synthesized vaso-relaxant, W-66, affinity matrix binds to a new extracellular matrix protein. (1991) (0)
Subject Index, Vol. 53, 1992 (2004) (0)
1421 – INHIBITION OF DOPAMINE β-HYDROXYLASE IN VIVO AND IN VITRO BY METHIMAZOL USED IN THE THERAPY OF HYPERTHYROIDISM (1977) (0)
[Proceedings: Characteristics of thyroid peroxidases in man and their antagonists]. (1974) (0)
Pharmacological properties of platelet strips. (1983) (0)
Alterations of neurocalcin, a calcium-binding protein, in Alzheimer’s disease. (1996) (0)
Relaxation of vascular smooth muscle by inhibitors of calmodulin and cyclic nucleotide dependent protein kinase (1984) (0)
Preparation of omega-(arylsulfonamido)-alkylamides (1975) (0)
Conformational Studies of Myosin Phosphorylated by Protein (1985) (0)
Monoamine oxidase activity of the thyroid glands in thyroid disease. (1969) (0)
Therapeutic potential of topical administration of H-1129, an isoquinoline sulfonamide derivative, in wet AMD and proliferative diabetic retinopathy (2017) (0)
Inhibition of human platelet aggregation by Ca2+ reseptive protein (calmodulin) interacting agents. (1980) (0)
Cyclic Nucleotide Phosphodiesterase in Platelets and Platelet Aggregability (1977) (0)
Time-course changes in blood pressure, urinary excretion of norepinephrine and dopamine after administration of fusaric acid in a single dose in elderly hypertensive patients. (1976) (0)
The role of protein phosphorylation on intracellular messenger system. (1988) (0)
Effects of metabolites of Molsidomine on coronary arteries - Coronary vasodilation and activation of guanylate cyclase (1983) (0)
Inhibition of platelet aggregation by a novel coronary vasodilator, molsidomine and its metabolites (1982) (0)
[Molecular pharmacology of intracellular Ca2+ messenger system in cardiovascular function: development and application of selective inhibitors]. (1992) (0)
Reciprocal control of autonomic nerves to chronotropism through opposing influence of cyclic GMP and cyclic AMP in isolated rabbit. sinoatrial node (1978) (0)
Circumvention of Multidrug Resistance by Suppression of MDR1 Gene Expression in Multidrug Resistant Cells (1993) (0)
[Molecular pharmacology on intracellular calcium messenger system]. (1986) (0)
Symmetric covalent linkage of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) results in novel derivatives with increased inhibitory activities against calcium/calmodulin complex. (1999) (0)
Blockade ofintracellular actions ofcalcium may protectagainst ischaemic damagetothegerbil brain (1991) (0)
[Shape change in human megakaryoblastic leukemia cells, MEG-01]. (1992) (0)
Release reaction of platelet and calcium ion (1984) (0)
Ca2+/Calmodulin-dcpendeni Protein Kinase V: Tissue Distribution and Immunohistochemical Localization in Rat Brain (1995) (0)
An anti-glaucoma agent, H-1129, binds to middle domain of Hsp90 (2012) (0)
[Role of cyclic GMP in blood platelets]. (1982) (0)
Molecular control of calcium-dependent protein phosphorylation reaction in vascular smooth muscle. (1988) (0)
Effect of dopamine β-hydroxylase inhibitors on isolated rabbit aorta (1976) (0)
Dihydrate d'hydrochlorure (s) - (-) 1 (4-fluoroisoquinoline-5-yl)sulfonyle-2-methyl-1,4-homopiperazine (2005) (0)
Studies on Chemical Modification of Monensin. Part 6. Preparation of C- 7 Modified Monensins via Protected 7-Oxomonensin and Evaluation of Their Ion Transport Activity. (2010) (0)
[Adrenergic receptor--classification, agonists and antagonists]. (1992) (0)
Calcium-dependent modulation of calmodulin-dependent enzyme activities by Ca2+-dependent protease (CANP) (1986) (0)
Inhibition of Acid Secretion in Gastric Parietal Cells by the Ca2+/ Calmodulin-Dependent Protein Kinase II Inhibitor KN-93. (1994) (0)
[Molecular pharmacological analysis of signal transduction by synthetic compounds]. (1997) (0)
[Cyclic nucleotides phosphodiesterases inhibitors]. (1991) (0)
Relaxation of isolated rabbit mesenteric artery by N4-substituted quinazoline derivatives (1981) (0)
Studies on antitumor activity of Bas idiomycete polysaccharide (Report 32) : Antitumor effect and the mechanism of ATOM prepared from cultured Agari cus blazei (1983) (0)
Binding of iproniazid to the polymeric forms of iodide peroxidase (1980) (0)
Selective inhibitors of phosphorylation in smooth muscle. (1987) (0)
Kinase II in Human B Lymphocytes (1995) (0)
Detection of modified beta 2-microglobulin (beta 2m) from amyloid deposits in tenosynovial tissue of carpal tunnel syndrome (CTS) (1994) (0)
The role of PDE in platelets (1995) (0)

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