H. Ichiro Yamamura

H. Ichiro Yamamura's AcademicInfluence.com Rankings

H. Ichiro Yamamura

Biology

#3172

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#4889

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Neuroscience

#283

World Rank

#298

Historical Rank

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Biology

H. Ichiro Yamamura's Degrees

PhD Neuroscience University of Tokyo
Masters Biology University of Tokyo
Bachelors Biology University of Tokyo

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H. Ichiro Yamamura's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Muscarinic cholinergic binding in rat brain. (1974) (1119)
Drugs, neurotransmitters, and schizophrenia. (1974) (792)
Discrimination of Multiple [3H]5‐Hydroxytryptamine Binding Sites by the Neuroleptic Spiperone in Rat Brain (1981) (633)
Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors. (1983) (631)
HIGH AFFINITY TRANSPORT OF CHOLINE INTO SYNAPTOSOMES OF RAT BRAIN 1 (1973) (579)
Antischizophrenic drugs and brain cholinergic receptors. Affinity for muscarinic sites predicts extrapyramidal effects. (1974) (405)
Neurotransmitter Receptor Binding (1984) (383)
Antidepressants and the muscarinic acetylcholine receptor. (1977) (383)
Muscimol binding in rat brain: Association with synaptic GABA receptors (1978) (364)
Pre- and postsynaptic neurochemical alterations in Alzheimer's disease (1978) (323)
Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization. (1978) (304)
Neurotoxic action of capsaicin on spinal substance P neurons (1980) (289)
Biochemical demonstration of dopaminergic receptors in rat and human brain using [3H]spiroperidol (1977) (289)
A unique regulatory profile and regional distribution of [3H]pirenzepine binding in the rat provide evidence for distinct M1 and M2 muscarinic receptor subtypes. (1983) (288)
Choline: High-Affinity Uptake by Rat Brain Synaptosomes (1972) (284)
Specific high-affinity binding sites for [3H]Ro 5-4864 in rat brain and kidney. (1983) (275)
SR141716A is an inverse agonist at the human cannabinoid CB1 receptor. (1997) (269)
Neurotransmitter receptor alterations in Parkinson's disease. (1977) (253)
Muscarinic Cholinergic Receptor Binding in the Longitudinal Muscle of the Guinea Pig Ileum with [3H]Quinuclidinyl Benzilate (1974) (240)
Muscarinic cholinergic receptor binding: regional distribution in monkey brain (1974) (235)
Specific high-affinity saturable binding of [3H] R05-4864 to benzodiazepine binding sites in the rat cerebral cortex. (1981) (232)
Modulation of rat brain α- and β-adrenergic receptor populations by lesions of the dorsal noradrenergic bundle (1980) (228)
Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. (1994) (220)
Localization of cholinergic muscarinic receptors in rat brain by light microscopic radioautography (1976) (219)
The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats. (1982) (219)
Extremely long-lasting antagonistic actions of nor-binaltorphimine (nor-BNI) in the mouse tail-flick test. (1992) (208)
Regional distribution of muscarinic cholinergic receptors in rat brain (1978) (206)
Benzodiazepine binding in human brain: characterization using [3H]flunitrazepam. (1978) (205)
Huntington's chorea. Changes in neurotransmitter receptors in the brain. (1976) (187)
Postsynaptic localization of muscarinic cholinergic receptor binding in rat hippocampus. (1974) (179)
Molecular biology and pharmacology of cloned opioid receptors 1 (1995) (179)
[3h]pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rat cerebral cortex. (1982) (171)
Age-related alterations in neurotransmitter receptors: An electrophysiological and biochemical analysis (1981) (171)
The interaction of [3H]nitrendipine with receptors for calcium antagonists in the cerebral cortex and heart of rats. (1982) (167)
[3H]Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia (1982) (162)
The delta-opioid receptor: molecular pharmacology, signal transduction, and the determination of drug efficacy. (1999) (162)
In vivo identification of muscarinic cholinergic receptor binding in rat brain. (1974) (160)
The effect of γ-aminobutyric acid on 3H-flunitrazepam binding in rat brain (1978) (156)
Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for μ opioid receptors (1986) (156)
Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain (1976) (145)
D-1 dopamine receptors in the rat brain: autoradiographic localization using [3H]SCH 23390. (1985) (142)
Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after direct labeling with [3H]-QNB and [3H]-pirenzepine. (1984) (141)
Methods in Neurotransmitter Receptor Analysis (1990) (140)
Further evidence for cholinergic habenulo-interpeduncular neurons: Pharmacologic and functional characteristics (1975) (140)
Benzodiazepine receptors: temperature dependence of [3H]flunitrazepam binding. (1979) (130)
Antinociceptive profile of biphalin, a dimeric enkephalin analog. (1993) (127)
Characterization of alpha-1 adrenergic receptors in the heart using [3H]WB4101: effect of 6-hydroxydopamine treatment. (1980) (126)
Cardiac muscarinic cholinergic receptor binding is regulated by Na+ and guanyl nucleotides. (1980) (125)
Cerebrospinal fluid gamma-aminobutyric acid variations in neurological disorders. (1977) (124)
Receptor alterations and drug tolerance. (1979) (120)
[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. II. Characterization and regulation of antagonist binding to putative muscarinic subtypes. (1986) (119)
Regional distribution of putative vasopressin receptors in rat brain and pituitary by quantitative autoradiography. (1984) (117)
Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability. (2000) (115)
Neuroleptics : neurochemical, behavioral, and clinical perspectives (1983) (114)
Design and synthesis of somatostatin analogues with topographical properties that lead to highly potent and specific mu opioid receptor antagonists with greatly reduced binding at somatostatin receptors. (1988) (113)
Effects of desipramine and yohimbine on α2- and β-adrenoreceptor sensitivity (1980) (110)
High affinity specific [3H](+)PN 200-110 binding to dihydropyridine receptors associated with calcium channels in rat cerebral cortex and heart. (1984) (106)
Regulation of substance P by nerve growth factor: disruption by capsaicin (1982) (105)
High affinity [3H]flunitrazepam binding: characterization, localization, and alteration in hypertension. (1981) (105)
Release of acetylcholine from hippocampal slices by potassium depolarization: dependence on high affinity choline uptake. (1974) (105)
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs (2000) (105)
Molecular pharmacology of muscarinic receptor heterogeneity. (1989) (104)
Cholinergic underactivity in human memory disorders. (1978) (103)
[3H]oxytocin binding sites in the rat brain demonstrated by quantitative light microscopic autoradiography. (1984) (102)
The localization of receptor binding sites in the substantia nigra and striatum of the rat (1979) (100)
An allosteric model for benzodiazepine receptor function. (1983) (99)
Neurotransmitter receptor binding: regional distribution in human brain (1977) (99)
[3H]-[H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2] ([3H]CTOP), a potent and highly selective peptide for mu opioid receptors in rat brain. (1989) (98)
Distribution and analgesia of [3H][D-Pen2, D-Pen5]enkephalin and two halogenated analogs after intravenous administration. (1991) (98)
Sodium-dependent high-affinity binding of [3H]hemicholinium-3 in the rat brain: a potentially selective marker for presynaptic cholinergic sites. (1984) (98)
Peripheral-type benzodiazepine receptors. (1993) (96)
Alterations in dopaminergic receptors in Huntington's disease. (1977) (95)
t‐[3H]Butylbicycloorthobenzoate: New Radioligand Probe for the γ‐Aminobutyric Acid–Regulated Chloride Ionophore (1985) (94)
Plasmon resonance studies of agonist/antagonist binding to the human delta-opioid receptor: new structural insights into receptor-ligand interactions. (2000) (94)
Differential light microscopic autoradiographic localization of muscarinic cholinergic receptors in the brainstem and spinal cord of the rat using [3H]pirenzepine. (1983) (94)
Biochemical characterization of the muscarinic cholinergic receptor in human brain: alterations in Huntington's disease. (1978) (94)
Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors. (1986) (92)
Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain. (1997) (92)
Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes. (1982) (92)
The effect of benzodiazepines and beta-carbolines on GABA-stimulated chloride influx by membrane vesicles from the rat cerebral cortex. (1986) (91)
Alterations in cardiac autonomic receptors following 6-hydroxydopamine treatment in rats. (1980) (91)
Characterization of [3H][2-D-penicillamine, 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma--glioma hybrid cell line (NG 108-15). (1985) (90)
The benzodiazepine receptor: its development and its modulation by gamma-aminobutyric acid. (1980) (90)
Placental beta-endorphin-like peptides. (1980) (90)
Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues. (2001) (89)
Direct Observation of G-protein Binding to the Human δ-Opioid Receptor Using Plasmon-Waveguide Resonance Spectroscopy* (2003) (89)
Quantitative light microscopic autoradiography of [3H]hemicholinium-3 binding sites in the rat central nervous system: a novel biochemical marker for mapping the distribution of cholinergic nerve terminals (1985) (88)
Biochemical indentification of the mammalian muscarinic cholinergic receptor. (1975) (86)
3H-Spiroperidol binding to two receptor sites in both the corpus striatum and frontal cortex of rat brain. (1978) (86)
Effects of bilateral ibotenate-induced lesions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex (1985) (86)
Conformationally constrained cyclic enkephalin analogs with pronounced delta opioid receptor agonist selectivity. (1983) (86)
The regulation of muscarinic cholinergic receptors by guanine nucleotides in cardiac tissue. (1979) (85)
Neuropeptides in sensory neurons. (1982) (85)
Modulation of the chloride ionophore by benzodiazepine receptor ligands: influence of gamma-aminobutyric acid and ligand efficacy. (1986) (83)
Topographic design of peptide neurotransmitters and hormones on stable backbone templates: relation of conformation and dynamics to bioactivity (1991) (83)
Conformationally restricted analogs of somatostatin with high mu-opiate receptor specificity. (1985) (81)
Muscarinic receptor: regulation by guanine nucleotides, ions, and N-ethylmaleimide. (1981) (80)
Constitutive Activity at the Cannabinoid CB1 Receptor Is Required for Behavioral Response to Noxious Chemical Stimulation of TRPV1: Antinociceptive Actions of CB1 Inverse Agonists (2008) (79)
Loss of striatal dopaminergic receptors after intrastriatal kainic acid injection. (1978) (79)
Huntington's chorea: Selective depletion of activity of angiotensin converting enzyme in the corpus striatum (1977) (78)
Ontogeny of mammalian myocardial β-adrenergic receptors (1979) (77)
Topographically designed analogues of [D-Pen,D-Pen5]enkephalin. (1991) (76)
Quantitative autoradiography of [3H]forskolin binding sites in the rat brain (1985) (76)
Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration. (1992) (73)
γ-aminobutyric acidB receptors in the rat brain: Quantitative autoradiographic localization using [3H](−)-baclofen (1985) (72)
Development of muscarinic cholinergic and GABA receptor binding in chick embryo brain (1976) (72)
Multiple benzodiazepine receptors and their regulation by γ-aminobutyric (1981) (71)
Topographical requirements for delta opioid ligands: common structural features of dermenkephalin and deltorphin. (1992) (71)
The influence of guanyl-5'-yl imidodiphosphate and sodium on muscarinic receptor binding in the rat brain and longitudinal muscle of the rat ileum. (1980) (71)
A high affinity, highly selective ligand for the delta opioid receptor: [3H]-[D-Pen2, pCl-Phe4, d-Pen5]enkephalin. (1989) (69)
Muscarinic receptor binding in rat brain using the agonist, [3H]cis methyldioxolane. (1980) (69)
A survey of substance P, somatostatin, and neurotensin levels in aging in the rat and human central nervous system (1981) (67)
Recovery of central respiratory function following anticholinesterase intoxication. (1976) (67)
Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain. (1983) (66)
AM630 antagonism of cannabinoid-stimulated [35S]GTPγS binding in the mouse brain (1997) (65)
Benzodiazepine receptor binding in young, mature and senescent rat brain and kidney (1981) (64)
Factors affecting performance of the push-pull cannula in brain. (1974) (64)
Huntington's disease: regional alteration in muscarinic cholinergic receptor binding in human brain. (1976) (64)
Reduction in basal ganglia and substantia nigra substance P levels in Huntington's disease (1981) (64)
Endomorphin-1 and endomorphin-2 are partial agonists at the human mu-opioid receptor. (1998) (63)
Modulation of gamma-aminobutyric acid-stimulated chloride influx by bicycloorthocarboxylates, bicyclophosphorus esters, polychlorocycloalkanes and other cage convulsants. (1988) (63)
Lanthanide-based time-resolved fluorescence of in cyto ligand-receptor interactions. (2004) (63)
[D-Pen2, L-Cys5]enkephalinamide and[D-Pen2, D-Cys5] enkephalinamide, conformationally constrained cyclic enkephalinamide analogs with delta receptor specificity. (1982) (63)
Effects of combined administration of amphetamine and iprindole on brain adrenergic receptors (1980) (61)
Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception. (1994) (61)
Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities. (1983) (61)
Alterations in central and peripheral adrenergic receptors in deoxycorticosterone/salt hypertensive rats. (1980) (60)
Computer-assisted autoradiographic localization of subtypes of serotonin1 receptors in rat brain (1983) (60)
δ-Opioid receptor agonists produce antinociception and [35S]GTPγS binding in μ receptor knockout mice (2000) (59)
[D-Pen2,D-Pen5]enkephalin analogues with increased affinity and selectivity for delta opioid receptors. (1990) (58)
Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling. (2008) (58)
Regulation of muscarinic receptor binding by guanine nucleotides and N-ethylmaleimide. (1980) (58)
The Intact Human Neuroblastoma Cell (SH‐SY5Y) Exhibits High‐Affinity [3H]Pirenzepine Binding Associated with Hydrolysis of Phosphatidylinositols (1988) (58)
delta 9-Tetrahydrocannabinol is a partial agonist of cannabinoid receptors in mouse brain. (1997) (58)
Light microscopic autoradiographic localization of delta opioid receptors in the rat brain using a highly selective bis-penicillamine cyclic enkephalin analog. (1986) (58)
Alterations in the benzodiazepine receptor of Huntington's diseased human brain (1979) (56)
Antinociceptive Structure-Activity Studies with Enkephalin-Based Opioid Glycopeptides (2004) (56)
AM630 is a competitive cannabinoid receptor antagonist in the guinea pig brain. (1997) (55)
Involvement of Raf-1 in chronic delta-opioid receptor agonist-mediated adenylyl cyclase superactivation. (2002) (55)
Choline transport by neuroblastoma cells in tissue culture (1974) (55)
AM630 is an inverse agonist at the human cannabinoid CB1 receptor. (1998) (54)
Vasopressin metabolite, AVP4-9, binding sites in brain: distribution distinct from that of parent peptide. (1986) (54)
Taurine: sodium-dependent, high-affinity transport into rat brain synaptosomes. (1978) (54)
A new, highly selective CCK-B receptor radioligand ([3H][N-methyl-Nle28,31]CCK26-33): evidence for CCK-B receptor heterogeneity. (1990) (54)
A muscarinic receptor with high affinity for pirenzepine mediates vagally induced bronchoconstriction. (1987) (53)
Characterization of muscarinic receptors of the rabbit ear artery smooth muscle and endothelium. (1986) (53)
Pharmacological differences between the high-affinity muscarinic agonist binding states of the rat heart and cerebral cortex labeled with (+)-[3H]cismethyldioxolane. (1984) (52)
Characterization of [3H]bradykinin binding sites in guinea-pig central nervous system: possible existence of B2 subtypes. (1989) (52)
Probing the Stereochemical Requirements for Receptor Recognition of δ Opioid Agonists through Topographic Modifications in Position 1 (1996) (51)
Opiate and neuroleptic receptor alterations in human schizophrenic brain tissue. (1980) (51)
Design, Synthesis, and Biological Evaluation of Novel Bifunctional C-Terminal-Modified Peptides for δ/μ Opioid Receptor Agonists and Neurokinin-1 Receptor Antagonists (2007) (51)
Autoradiographic localization of 'peripheral' benzodiazepine binding sites in the rat brain and kidney using [3H]RO5-4864. (1983) (51)
Converging Protein Kinase Pathways Mediate Adenylyl Cyclase Superactivation upon Chronic δ-Opioid Agonist Treatment (2003) (50)
Modulation of benzodiazepine receptor binding: insight into pharmacological efficacy. (1982) (50)
[D-Pen2,D-Pen5]enkephalin (DPDPE): a δ-selective enkephalin with low affinity for μ1 opiate binding sites (1986) (50)
ACETYLCHOLINESTERASE TURNOVER IN BRAIN, CEREBROSPINAL FLUID AND PLASMA (1975) (50)
Localization of dopamine receptors in rat brain (1979) (50)
Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. (1996) (49)
Interactions of pyrethroid insecticides with chloride ionophore-associated binding sites. (1985) (49)
De novo synthesis of acetylcholinesterase in guinea pig retina after inhibition by pinacolyl methyl-phosphonofluoridate (1971) (49)
Development of a lanthanide-based assay for detection of receptor-ligand interactions at the delta-opioid receptor. (2005) (48)
Thermal analgesia and substance P depletion induced by capsaicin in guinea-pigs (1981) (48)
A muscarinic receptor subtype modulates vagally stimulated bronchial contraction. (1988) (48)
Selectivity, Cooperativity, and Reciprocity in the Interactions between the δ-Opioid Receptor, Its Ligands, and G-proteins* (2004) (48)
Agonist binding to multiple muscarinic receptors. (1984) (48)
Lipid bilayers on polyacrylamide brushes for inclusion of membrane proteins. (2005) (47)
Failure of septal lesions to alter muscarinic cholinergic or benzodiazepine binding sites in hippocampus of rat brain (1980) (47)
Characterization of a tachykinin peptide NK2 receptor transfected into murine fibroblast B82 cells. (1991) (47)
Huntington's disease and its animal model: alterations in kainic acid binding. (1979) (47)
De Novo Design, Synthesis, and Biological Activities of High-Affinity and Selective Non-Peptide Agonists of the δ-Opioid Receptor‖ (1998) (47)
High-affinity 3H-substance P binding to longitudinal muscle membranes of the guinea pig small intestine. (1984) (47)
Characterization of [3H]naltrindole binding to delta opioid receptors in mouse brain and mouse vas deferens: evidence for delta opioid receptor heterogeneity. (1994) (46)
Temperature-dependent modulation of [3H]nitrendipine binding by the calcium channel antagonists verapamil and diltiazem in rat brain synaptosomes. (1984) (45)
Ring substituted and other conformationally constrained tyrosine analogues of [D-Pen2,D-Pen5]enkephalin with delta opioid receptor selectivity. (1992) (45)
Regional heterogeneity of benzodiazepine receptors at 37 degrees C: an in vitro study in various regions of the rat brain. (1982) (45)
The cloned murine M1 muscarinic receptor is associated with the hydrolysis of phosphatidylinositols in transfected murine B82 cells. (1988) (45)
gamma-Aminobutyric acid enhancement of CL 218,872 affinity and evidence of benzodiazepine receptor heterogeneity. (1981) (45)
Inhibition of in vivo 3H-spiperone binding by the proposed antipsychotic des-try1-γ-endorphin (1979) (45)
Identification of adenylyl cyclase isoenzymes in CHO and B82 cells. (1998) (44)
A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. (2008) (44)
Molecular mechanisms of excitatory signaling upon chronic opioid agonist treatment. (2003) (44)
The m2 muscarinic acetylcholine receptors are coupled to multiple signaling pathways via pertussis toxin-sensitive guanine nucleotide regulatory proteins. (1991) (43)
Regional differences in ethylcholine mustard aziridinium ion (AF64A)-induced deficits in presynaptic cholinergic markers for the rat central nervous system. (1985) (43)
Human delta opioid receptor: functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective nonpeptidic agonist SNC-80. (1996) (43)
Neurotransmitter receptors-biochemistry and alterations in nueropsychiatric disorders. (1980) (43)
Examination of des-tyrosine1-gamma-endorphin activity at oH-spiroperidol binding sites in rat brain. (1979) (42)
The third extracellular loop of the human delta-opioid receptor determines the selectivity of delta-opioid agonists. (1996) (42)
Characterization of [3H]naltrindole binding to delta opioid receptors in rat brain. (1992) (42)
Agonist-specific regulation of the δ-opioid receptor (2004) (42)
Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonists. (2009) (42)
Nicotinic cholinergic receptors in rat brain identified by [125I]Naja naja siamensis α-toxin binding (1977) (42)
Cholecystokinin analogues with high affinity and selectivity for brain membrane receptors. (2009) (42)
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin. (1999) (41)
Differential supersensitivity of beta-receptor subtypes in rat cortex and cerebellum after central noradrenergic denervation. (1980) (41)
Pharmacological effects of MDL 11,939: A selective, centrally acting antagonist of 5‐HT2 receptors (1988) (40)
Antisense oligodeoxynucleotide treatment to the brain cannabinoid receptor inhibits antinociception (1996) (40)
Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex. (1988) (40)
Modulation of rat brain alpha- and beta-adrenergic receptor populations by lesion of the dorsal noradrenergic bundle. (1980) (40)
[3H]AF-DX 116 labels subsets of muscarinic cholinergic receptors in rat brain and heart. (1987) (40)
Ontogeny of mammalian cardiac α1-adrenergic receptors (1980) (39)
Enhancement of morphine antinociception by a CCKB antagonist in mice is mediated via opioid delta receptors. (1996) (39)
Neurotransmitter Receptors (2012) (39)
Muscarinic cholinergic receptors in mammalian retina (1978) (39)
Cloning of the rat M3, M4 and M5 muscarinic acetylcholine receptor genes by the polymerase chain reaction (PCR) and the pharmacological characterization of the expressed genes. (1992) (39)
Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for mu opioid receptors. (1986) (39)
In vivo identification of calcium antagonist binding sites using [3H]nitrendipine. (1983) (39)
The benzodiazepine receptor of mammalian brain. (1980) (39)
A novel pyrazoloquinoline that interacts with brain benzodiazepine receptors: characterization of some in vitro and in vivo properties of CGS 9896. (1982) (38)
gamma-Aminobutyric acid regulation of the benzodiazepine receptor: biochemical evidence for pharmacologically different effects of benzodiazepines and propyl beta-carboline-3-carboxylate. (1981) (38)
Differential ontogeny of putative M1 and M2 muscarinic receptor binding sites in the murine cerebral cortex and heart. (1985) (38)
Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers. (2005) (38)
Differential regulation of muscarinic agonist binding sites following chronic cholinesterase inhibition. (1980) (37)
Phorbol esters alter muscarinic receptor binding and inhibit polyphosphoinositide breakdown in human neuroblastoma (SH-SY5Y) cells. (1986) (37)
Neuronal Uptake of Neurotransmitters and their Precursors: Studies with “Transmitter” Amino Acids and Choline (1973) (37)
Alterations of muscarinic cholinergic receprtors in the rat striatum after kainic acid injections (1978) (37)
Synthesis using a Fmoc-based strategy and biological activities of some reduced peptide bond pseudopeptide analogues of dynorphin A1. (1995) (37)
The regulation of cardiac alpha 1-adrenergic receptors by guanine nucleotides and by muscarinic cholinergic agonists. (1980) (36)
CL 218872 antagonism of diazepam induced loss of righting reflex: evidence for partial agonistic activity at the benzodiazepine receptor. (1983) (36)
Biousian glycopeptides penetrate the blood-brain barrier (2005) (36)
Characterization of muscarinic cholinergic receptor subtypes in human peripheral lung. (1988) (36)
Muscarinic cholinergic ligand binding to intact mouse pituitary tumor cells (AtT-20/D16-16) coupling with two biochemical effectors: adenylate cyclase and phosphatidylinositol turnover. (1986) (36)
[3H]Pirenzepine identifies putative M1 muscarinic receptors in human stellate ganglia (1984) (36)
Identification of B2 bradykinin binding sites in guinea-pig brain. (1988) (36)
Opioid receptor binding properties of analgesic analogues of cholecystokinin octapeptide. (1991) (36)
Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4. (1997) (35)
Expression of α-Transducin in Chinese Hamster Ovary Cells Stably Transfected with the Human δ-Opioid Receptor Attenuates Chronic Opioid Agonist-Induced Adenylyl Cyclase Superactivation (2001) (35)
Multiple 3H-5-hydroxytryptamine binding sites in rat brain. (1981) (35)
Cyclic enkephalin analogues with exceptional potency and selectivity for δ-opioid receptors (1997) (35)
Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE). (2001) (35)
Relative efficacies of δ-opioid receptor agonists at the cloned human δ-opioid receptor (1997) (34)
Decreased receptor-binding sites for kainic acid in brains of patients with Huntington's disease. (1981) (34)
[3H]CL 218,872, a novel triazolopyridazine which labels the benzodiazepine receptors in rat brain. (1982) (34)
Blockade by morphine of acetylcholine release from the caudate nucleus in the mid-pontine pretrigeminal cat (1975) (33)
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. (2008) (33)
Effect of ethanol on receptor-stimulated phosphatidic acid and polyphosphoinositide metabolism in mouse brain. (1986) (33)
The effects of beta-diethylaminoethyl-diphenylpropylacetate (SKE 525-A) on biological membranes. I. SKF 525-A-induced stabilization of human erythrocytes. (1968) (33)
Benzodiazepine receptors: The effect of GABA on their characteristics in human brain and their alteration in Huntington's disease (1980) (33)
Comparison of the distribution of convulsant/barbiturate and benzodiazepine receptors using light microscopic autoradiography. (1983) (33)
Benzodiazepine receptors: alterations in mutant mouse cerebellum. (1979) (33)
Acute diazepam administration produces rapid increases in brain benzodiazepine receptor density. (1979) (33)
[3H]spiroxatrine labels a serotonin1A-like site in the rat hippocampus. (1987) (33)
AF-DX 116 discriminates between muscarinic M2 receptors of the heart and vasculature. (1987) (33)
Regional Distribution of Amino Acids in Friedreich's Ataxia Brains (1979) (33)
Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner. (2008) (33)
Reduced density of sodium-dependent [3H]hemicholinium-3 binding sites in the anterior cerebral cortex of rats following chemical destruction of the nucleus basalis magnocellularis. (1984) (32)
Striatal muscarinic receptors: regulation by dopaminergic agonists. (1981) (32)
Differentiation between rat brain and mouse vas deferens δ opioid receptors (1990) (32)
Quantitative autoradiography of M2 muscarinic receptors in the rat brain identified by using a selective radioligand [3H]AF-DX 116 (1989) (32)
Assessment of Stereoselectivity of Trimethylphenylalanine Analogues of δ‐Opioid [D‐Pen2,D‐Pen5]‐Enkephalin (2000) (31)
Benzodiazepine anticonvulsant action: gamma-aminobutyric acid-dependent modulation of the chloride ionophore. (1984) (31)
Phosphorylation of adenylyl cyclase VI upon chronic δ-opioid receptor stimulation (1999) (30)
Sodium-dependent, high-affinity taurine transport into rat brain synaptosomes. (1980) (30)
Differential effect of gamma-aminobutyric acid on benzodiazepine receptor subtypes labeled by [3H]propyl beta-carboline-3-carboxylate in rat brain. (1983) (30)
On the ability of choline and its analogues to interact with muscarinic cholinergic receptors in the rat brain. (1979) (30)
Alteractions in brain opiate receptors in Parkinson's disease (1979) (30)
Adenylate cyclase and beta adrenergic receptor development in the mouse heart. (1982) (29)
Characterization of muscarinic acetylcholine receptors in human labial salivary glands. (1990) (29)
The relationship between agonist states of the M1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing different receptor densities. (1989) (29)
Regulation of airway muscarinic cholinergic receptor subtypes by chronic anticholinergic treatment. (1995) (29)
Real time differentiation of G-protein coupled receptor (GPCR) agonist and antagonist by two photon fluorescence laser microscopy. (2004) (29)
Syntheses, opioid binding affinities, and potencies of dynorphin A analogues substituted in positions, 1, 6, 7, 8 and 10. (2009) (29)
Light microscopic autoradiographic localization of [3H] substance P binding sites in rat thoracic spinal cord. (1984) (28)
Human δ opioid receptor: A stable cell line for functional studies of opioids (1995) (28)
Autoradiographic localization of “peripheral-type” benzodiazepine binding sites in the rat brain, heart and kidney (1985) (28)
Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies. (2011) (28)
Properties of TAN-67, a nonpeptide δ-opioid receptor agonist, at cloned human δ-and μ-opioid receptors (1995) (27)
Differential regulation of high-affinity agonist binding to muscarinic sites in the rat heart, cerebellum, and cerebral cortex. (1983) (27)
The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety. (2009) (27)
Characterization of high affinity [3H]pirenzepine and (-)-[3H] quinuclidinyl benzilate binding to muscarinic cholinergic receptors in rabbit peripheral lung. (1987) (27)
Effect of chronic ethanol consumption on central and peripheral type benzodiazepine binding sites in the mouse brain (1983) (27)
Agonist-specific down-regulation of the human δ-opioid receptor (2003) (27)
Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity. (1993) (26)
Muscarinic receptors and novel strategies for the treatment of age-related brain disorders. (1994) (26)
Quantitative autoradiography of [3H]CTOP binding to mu opioid receptors in rat brain. (1988) (26)
Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice. (2006) (26)
3H-flunitrazepam binding to bovine retina and the effect of GABA thereon (1980) (26)
Characterization of brain dopaminergic receptors in Huntington's disease. (1978) (26)
Functional and biochemical basis for multiple muscarinic acetylcholine receptors (1985) (25)
Carbachol stimulation of phosphatidic acid synthesis: competitive inhibition by pirenzepine in synaptosomes from rat cerebral cortex. (1985) (25)
Light microscopic autoradiographic identification of picrotoxin/barbiturate binding sites in rat brain with [35S]t-butyl-bicyclophosphothionate. (1983) (25)
Effects of modifications of residues in position 3 of dynorphin A(1-11)-NH2 on kappa receptor selectivity and potency. (1996) (25)
Muscarinic cholinergic receptor heterogeneity (1982) (25)
Topographical requirements for delta opioid ligands: presence of a carboxyl group in position 4 is not critical for deltorphin high delta receptor affinity and analgesic activity. (1991) (25)
Design of cyclic deltorphins and dermenkephalins with a disulfide bridge leads to analogues with high selectivity for delta-opioid receptors. (1994) (25)
Photoaffinity labeling of the benzodiazepine receptor in bovine cerebral cortex. (1979) (24)
Chimeric M1/M2 muscarinic receptors: correlation of ligand selectivity and functional coupling with structural modifications. (1992) (24)
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells. (1989) (24)
Differences between rats and guinea pigs in gastrointestinal and nervous system substance P levels (1981) (24)
Differentiation of benzodiazepine receptor agonist and antagonist: sparing of [3H]benzodiazepine antagonist binding following the photolabelling of benzodiazepine receptors. (1982) (24)
Somatostatin analogs with affinity for opiate receptors in rat brain binding assay (1985) (24)
The coupling of muscarinic receptors to hydrolysis of inositol lipids in human neuroblastoma SH-SY5Y cells (1989) (23)
The stereochemical requirements of the novel δ-opioid selective dipeptide antagonist TMT-Tic (1997) (23)
Differential down-regulation of the human δ-opioid receptor by SNC80 and [d-Pen2,d-Pen5]enkephalin (2000) (23)
Heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex demonstrated by the selective antagonist AF-DX 116. (1987) (23)
Design and synthesis of highly potent and selective cyclic dynorphin A analogues. (1990) (23)
AM630 antagonism of cannabinoid-stimulated [35S]GTP gamma S binding in the mouse brain. (1997) (23)
Maturation of mammalian myocardial muscarinic cholinergic receptors. (1978) (23)
Localization of [3H]forskolin binding sites in the rat brain using quantitative autoradiography. (1984) (23)
PK 8165 and PK 9084, two quinoline derivatives with anxiolytic properties, antagonize the anticonvulsant effects of diazepam (1983) (23)
The cloning and sequence analysis of the rat serotonin-1A receptor gene. (1990) (23)
Characterization of receptors for platelet-activating factor in guinea pig lung membranes. (1990) (23)
The Nature of Muscarinic Receptor Binding (1983) (22)
New paradigms and tools in drug design for pain and addiction (2006) (22)
Cell Signaling and Trafficking of Human Melanocortin Receptors in Real Time Using Two‐photon Fluorescence and Confocal Laser Microscopy: Differentiation of Agonists and Antagonists (2006) (22)
Peptide targeting and delivery across the blood-brain barrier utilizing synthetic triglyceride esters: design, synthesis, and bioactivity. (1997) (22)
Sustained Morphine Treatment Augments Capsaicin-Evoked Calcitonin Gene-Related Peptide Release from Primary Sensory Neurons in a Protein Kinase A- and Raf-1-Dependent Manner (2009) (22)
Effects of chemical sympathectomy with 6-hydroxydopamine on α- and β-adrenoceptors and muscarinic cholinoceptors in rat kidney (1986) (21)
Exploring the structure-activity relationships of [1-(4-tert-butyl-3'-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand. (1999) (21)
Effects of seizures and antiepileptic drugs on benzodiazepine receptors in rat brain. (1984) (21)
Chronic exposure to a beta 2-adrenoceptor agonist increases the airway response to methacholine. (1993) (21)
Effects of Amitriptyline on GABA-stimulated 36Cl− uptake in relation to a behavioral model of depression (1995) (21)
High performance liquid chromatography of pharmacologically active amines and peptides in biological materials. (1982) (21)
Autoradiographic demonstration of the selectivity of two 1-N-trifluoroethyl benzodiazepines for the BZD-1 receptors in the rat brain (1985) (21)
delta-Opioid receptor: the third extracellular loop determines naltrindole selectivity. (1996) (21)
Muscarinic receptor-mediated hydrolysis of phosphatidylinositols in human neuroblastoma (SH-SY5Y) cells is sensitive to pertussis toxin (1988) (21)
Modifications of the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide. (1998) (21)
[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of agonist binding to putative muscarinic subtypes. (1986) (21)
A new approach to enhance bioavailability of biologically active peptides: conjugation of a δ opioid agonist to β-cyclodextrin (1993) (21)
The effect of temperature on CL 218872 and propyl beta-carboline-3-carboxylate inhibition of [3H]-flunitrazepam binding in rat brain. (1982) (20)
Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines. (2010) (20)
Mathematical analysis of the kinetics of competitive inhibition in neurotransmitter receptor binding assays. (1981) (20)
Probes for Narcotic Receptor-Mediated Phenomena. 25.1 Synthesis and Evaluation of N-Alkyl-Substituted (α-Piperazinylbenzyl)benzamides as Novel, Highly Selective δ Opioid Receptor Agonists (1997) (20)
Effect of propranolol on the blockade of alpha adrenergic receptors. (1968) (20)
Chronic morphine-mediated adenylyl cyclase superactivation is attenuated by the Raf-1 inhibitor, GW5074. (2006) (20)
New endomorphin analogs with mu-agonist and delta-antagonist properties (2004) (20)
Renal benzodiazepine binding increases during deoxycorticosterone/salt hypertension in rats. (1980) (20)
A minority of muscarinic receptors mediate rabbit tracheal smooth muscle contraction. (1992) (20)
Synthesis of tritium labeled Ac-[Nle4, D-Phe7]-alpha-MSH4-11-NH2: a superpotent melanotropin with prolonged biological activity. (1984) (20)
Modulation of GABA-stimulated chloride influx by β-carbolines in rat brain membrane vesicles (1988) (20)
Study of the sympathomimetic action of cyclohexylamine, a possible metabolite of cyclamate. (1968) (20)
Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82). (1991) (20)
Design, synthesis, and biological properties of highly potent cyclic dynorphin A analogues. Analogues cyclized between positions 5 and 11. (1994) (20)
Agonist-specific regulation of the delta-opioid receptor. (2004) (20)
The role of the G protein γ2 subunit in opioid antinociception in mice (2000) (19)
Pharmacological characterization of a novel muscarinic partial agonist, YM796, in transfected cells expressing the m1 or m2 muscarinic receptor gene. (1992) (19)
Effects of pentobarbital on t-[35S]butylbicyclophosphorothionate and [3H]flunitrazepam binding to membrane-bound and solubilized preparations from rat forebrain. (1985) (19)
Effects of 2-PAMC1 and toxogonin on retinal and brain acetylcholinesterase inhibited by sarin. (1971) (19)
Himbacine recognizes a high affinity subtype of M2 muscarinic cholinergic receptors in the rat cerebral cortex (1988) (19)
The influence of guanyl-5'-yl imidodiphosphate and sodium chloride on the binding of the muscarinic agonist, [3H] cis methyldioxolane. (1980) (19)
Pharmacological comparison of the cloned human and rat M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line. (1998) (19)
Cyclic enkephalin analogs with exceptional potency at peripheral delta opioid receptors. (1994) (19)
Quantitative Evaluation of Human δ Opioid Receptor Desensitization Using the Operational Model of Drug Action (2007) (19)
Autoradiographic localization of muscarinic agonist binding sites in the rat central nervous system with (+)-cis-[3H]methyldioxolane (1985) (19)
Characterization of postsynaptic beta-adrenergic receptors and presynaptic muscarinic cholinergic receptors in the rat spleen. (1982) (19)
Highly kappa receptor-selective dynorphin A analogues with modifications in position 3 of dynorphin A(1-11)-NH2. (1995) (19)
Modulation of GABA-stimulated chloride influx into membrane vesicles from rat cerebral cortex by triazolobenzodiazepines. (1988) (18)
Light microscopic autoradiographic localization of somatostatin receptors in the rat brain. (1985) (18)
Benzodiazepine receptor heterogeneity: possible molecular basis and functional significance. (1984) (18)
Muscarinic receptor binding and behavioral effects of atropine following chronic catecholamine depletion or acetylcholinesterase inhibition in rats (1980) (18)
The influence of temperature and gamma-aminobutyric acid on benzodiazepine receptor subtypes in the hippocampus of the rat. (1982) (18)
Ontogeny of mammalian myocardial beta-adrenergic receptors. (1979) (18)
Muscarinic cholinergic receptor binding: influence of pimozide and chlorpromazine metabolites. (1976) (18)
High-affinity [3H]pirenzepine binding to putative M1 muscarinic sites in the neuroblastoma x glioma hybrid cell line (NG 108-15). (1984) (18)
Autoradiographic localization of nicotinic receptor binding in rat brain using [3H]methylcarbamylcholine, a novel radioligand. (1987) (18)
Functional selectivity in cannabinoid signaling. (2008) (18)
Guinea pig brain acetylcholinesterase: partial purification by affinity chromatography. (1973) (17)
Autoradiographic localization of [3H] [MePhe3,D-Pro4]morphiceptin ([3H]PL017) to mu opioid receptors in rat brain. (1987) (17)
Conformationally restricted tricyclic antidepressants. 1. Octahydrodibenzazepinonaphthyridines as rigid imipramine analogues. (1980) (17)
Angiotensin II receptor binding and actions in NG108-15 cells. (1989) (17)
The efficacy of δ-opioid receptor-selective drugs (1998) (17)
Comparison of 3H-Muscimol and 3H-GABA Receptor Binding in Rat Brain (1978) (17)
The effect of GABA on in vitro binding of two novel non-benzodiazepines, PK 8165 and CGS 8216, to benzodiazepine receptors in the rat brain. (1982) (17)
Identification of β-endorphin-(6–17) as the principal metabolite of des-tyrosine-γ-endorphin (DTγE) in vitro and assessment of its activity in neurotransmitter receptor binding assays (1982) (16)
Synthesis and biological properties of gamma-glutamyl-dermorphin, a prodrug. (1996) (16)
Design, Synthesis, and Biological Activities of Cyclic Lactam Peptide Analogues of Dynorphin A(1−11)-NH21 (1996) (16)
Mutation W284L of the human delta opioid receptor reveals agonist specific receptor conformations for G protein activation. (2001) (16)
Autoradiographic localization of delta opioid receptors in the rat brain using a highly selective bis-penicillamine cyclic enkephalin analog. (1985) (16)
Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs. (1993) (16)
Novel design of bicyclic beta-turn dipeptides on solid-phase supports and synthesis of [3.3.0]-Bicyclo([2,3])-leu-enkephalin analogues. (2004) (16)
Synthesis of highly mu and delta opioid receptor selective peptides containing a photoaffinity group. (1989) (15)
Conformationally restricted cyclic analogues of substance P: insight into the receptor binding process. (1985) (15)
Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor. (1990) (15)
Possible bases for the anticonvulsant action of taurine. (1983) (15)
Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia. (2008) (15)
delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. (2000) (15)
Potent enhancement of [3H]nitrendipine binding in rat cerebral cortical and cardiac homogenates: a putative mechanism for the action of MDL 12,330A. (1985) (15)
Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays. (2000) (15)
Modulation of GABA-stimulated chloride influx into membrane vesicles from rat cerebral cortex by benzodiazepines and nonbenzodiazepines. (1988) (15)
Delta opioid receptor radioligands. (1992) (15)
The regulation of cardiac muscarinic cholinergic receptors by isoproterenol. (1980) (15)
Rapid desensitization of central beta-receptors and up-regulation of alpha 2-receptors following antidepressant treatment. (1982) (14)
Differential regulation of M2 muscarinic receptors by guanine nucleotides in rat cerebral cortical and cardiac membranes. (1987) (14)
H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2: a potent and selective antagonist opioid receptors. (1986) (14)
Reduced peptide bond cyclic somatostatin based opioid octapeptides. Synthesis, conformational properties and pharmacological characterization. (2009) (14)
Sodium-dependent high affinity transport of taurine into rat brain synaptosomes. (1976) (14)
[L-Ala3]DPDPE: a new enkephalin analog with a unique opioid receptor activity profile. Further evidence of delta-opioid receptor multiplicity. (1994) (14)
Agonist-specific down-regulation of the human delta-opioid receptor. (2003) (14)
Inhibition of GABA-stimulated chloride influx by the convulsant benzodiazepines Ro 5-3663 and Ro 5-4864 into membrane vesicles from rat cerebral cortex. (1987) (14)
[125I-Tyr1]biphalin binding to opioid receptors of rat brain and NG108-15 cell membranes. (1998) (14)
Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists. (2007) (14)
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats. (1985) (13)
Molecular Organization of Receptors (1995) (13)
The effects of cell isolation techniques on neuronal membrane receptors (1975) (13)
Placental β-Endorphin-Like Peptides (1980) (13)
Synthesis and biological activities of linear and cyclic enkephalin analogues containing a psi (E,CH = CH) or psi (CH2CH2) isosteric replacement. (2009) (13)
Neuropeptides in normal and pathological basal ganglia. (1982) (13)
Depression by morphine of the resting and evoked release of [3H]-acetylcholine from the cat caudate nucleus in vivo (1977) (13)
Relative stability of α-melanotropin and related analogues to rat brain homogenates (1984) (13)
Binding of BW 373U86, a non-peptidic delta opioid receptor agonist, is not regulated by guanine nucleotides and sodium. (1993) (13)
Pharmacologic and biochemical aspects of neurotransmitter receptors (1983) (13)
Solubilization with digitonin alters the kinetics of pirenzepine binding to muscarinic receptors from rat forebrain and heart. (1987) (13)
Morphine promotes phosphorylation of the human δ-opioid receptor at serine 363 (2005) (13)
Characterization of rabbit ear artery opioid receptors using a delta-selective agonist and antagonist. (1987) (13)
The ontogeny of specific binding sites for the calcium channel antagonist, nitrendipine, in mouse heart and brain (1983) (13)
Isolation and characterization of in vitro central beta-endorphin metabolism in schizophrenia. (1983) (12)
Differentiation of receptor subtypes by thermodynamic analysis: application to opioid delta receptors. (1994) (12)
β-Carboline interactions at the BZ-GABA Receptor chloride-ionophore complex in the rat cerebral cortex (1989) (12)
Topographical requirements for delta opioid ligands: The synthesis and biological properties of a cyclic analogue of deltorphin I (1992) (12)
Down-regulation and desensitization of the muscarinic M1 and M2 receptors in transfected fibroblast B82 cells. (1994) (12)
A simple and rapid radio-receptor assay for the estimation of acetylcholine. (1982) (12)
Photoaffinity Labeling of Benzodiazepine Receptors in Rat Brain with Flunitrazepam Alters the Affinity of Benzodiazepine Receptor Agonist But Not Antagonist Binding (1983) (12)
The use of topographical constraints in receptor mapping: investigation of the topographical requirements of the tryptophan 30 residue for receptor binding of Asp-Tyr-D-Phe-Gly-Trp-(N-Me)Nle-Asp-Phe-NH2 (SNF 9007), a cholecystokinin (26-33) analogue that binds to both CCK-B and delta-opioid receptor (1996) (12)
Relative efficacies of delta-opioid receptor agonists at the cloned human delta-opioid receptor. (1997) (12)
Expression of alpha-transducin in Chinese hamster ovary cells stably transfected with the human delta-opioid receptor attenuates chronic opioid agonist-induced adenylyl cyclase superactivation. (2001) (12)
Antinociception depends on the presence of G protein γ2-subunits in brain (2005) (12)
The measurement of free nitrendipine in human serum by an equilibrium dialysis - radioreceptor assay. (1983) (12)
The interaction of a benzodiazepine receptor antagonist (Ro15–1788) with GABA and GABA receptor antagonists at the GABAA receptor chloride-ionophore complex (1991) (12)
Reductions in retinal gamma-aminobutyric acid (GABA) content and in [3H]flunitrazepam binding after postnatal monosodium glutamate injections in rats. (1981) (12)
Conformationally restricted phenothiazine neuroleptics. 1. 3-(Dimethylamino)-1,2,3,4-tetrahydroazepino[3,2,1-kl]phenothiazine. (1980) (12)
(2S, 3R)TMT-L-Tic-OH is a potent inverse agonist at the human δ-opioid receptor (1999) (12)
Opioid Peptides: Simultaneous δ Agonism and μ Antagonism in Somatostatin Analogues (1997) (12)
Decreased Benzodiazepine Receptor Density in Rat Cerebellum Following Neurotoxic Doses of Phenytoin (1980) (11)
Selective anxiolytics: are the actions related to partial "agonist" activity or a preferential affinity for benzodiazepine receptor subtypes? (1983) (11)
Muscarinic cholinergic receptor binding in brain (1974) (11)
Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]‐Leu‐enkephalin analogues (2005) (11)
Trp284 of the Human δ Opioid Receptor is Required for SNC121 Binding but Not Binding of pCl-DPDPE, Deltorphin II or Naltrindole (1995) (11)
Unexpected antinociceptive potency of cyclic [D-Tca1]CTAP: potential for a novel mechanism of action. (1993) (11)
Accelerated communication a cloned NK2 receptor mediates phosphatidylinositol hydrolysis in a transfected murine fibrolast (1990) (11)
High affinity inhibition of [3H]-flunitrazepam binding to brain benzodiazepine receptors by CGS 9896, a novel pyrazoloquinoline. (1982) (11)
A red clover (Trifolium pratense) phase II clinical extract possesses opiate activity. (2007) (11)
Pharmacological characterization of glucocorticoid receptors in primary human bronchial epithelial cells. (1999) (11)
Muscarinic receptor subtype in porcine coronary artery. (1988) (11)
THE RELEASE IN VIVO OF [3H]ACETYLCHOLINE FROM CAT CAUDATE NUCLEUS AND CEREBRAL CORTEX BY ATROPINE, PENTYLENETETRAZOL, K+‐DEPOLARIZATION AND ELECTRICAL STIMULATION (1975) (11)
Lactamimides: a novel chemical class of calcium antagonists with diltiazem-like properties. (1989) (11)
Delta opioid receptor-selective ligands: [D-Pen2,D-Pen5]enkephalin-dermenkephalin chimeric peptides. (1991) (11)
Decreased muscarinic receptor density in the aged rat brain. (1988) (10)
Light microscopic autoradiographic localization of [3H]pirenzepine and [3H](-)quinuclidinyl benzilate binding in human stellate ganglia. (1984) (10)
Phosphorylation of adenylyl cyclase VI upon chronic delta-opioid receptor stimulation. (1999) (10)
Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363. (2005) (10)
Vasopressin metabolite peptide (AVP-(4-9)) binding sites in rat kidney: distribution distinct from vasopressin binding sites. (1985) (10)
Competitive inhibition of phosphoinositide hydrolysis by the muscarinic receptor antagonist AF-DX 116 is of low affinity in mouse cerebral cortex (1987) (10)
Differential regulation of putative M1/M2 muscarinic receptors: implications for different receptor-effector coupling mechanisms. (1984) (10)
Effects of repeated withdrawal of cerebrospinal fluid by cisternal puncture on cisternal protein levels in the unanesthetized cat. (1973) (10)
Properties of TAN-67, a nonpeptidic delta-opioid receptor agonist, at cloned human delta- and mu-opioid receptors. (1995) (10)
Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin. (2000) (10)
Heterogeneity of Benzodiazepine Receptors (1984) (10)
Characterization of κ opioid receptors in the rabbit ear artery (1988) (10)
(2S,3R)β-Methyl-2′,6′-dimethyltyrosine-l-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-l-Tic-OH] Is a Potent, Selective δ-Opioid Receptor Antagonist in Mouse Brain (2003) (10)
De novo synthesis of acetylcholinesterase in guinea pig retina after inhibition by pinacolyl methylphosphonofluoridate. (1971) (10)
Amoxapine inhibition of GABA-stimulated chloride conductance: investigations of potential sites of activity. (1989) (10)
ALTERATIONS IN MUSCARINIC CHOLINERGIC RECEPTOR BINDING IN HUNTINGTON'S DISEASE (1979) (9)
Tryptophan-norleucine 1,5-disubstituted tetrazoles as cis peptide bond mimics: Investigation of the bioactive conformation of a potent and selective peptide for the cholecystokinin-B receptor (1993) (9)
Highly potent and selective cholecystokinin analogues for the CCK-B receptor (1991) (9)
[3H][D-Pen2, D-Pen5]enkephalin binding to delta opioid receptors on intact neuroblastoma-glioma (NG 108-15) hybrid cells. (1990) (9)
[3H]pirenzepine specifically labels a high affinity muscarinic receptor in the rat cerebral cortex. (1983) (8)
Characterization in guinea pigs of the sensory effects of the putative substance P neurotoxin capsaicin. (1981) (8)
Analogues of cholecystokinin 26–33 selective for B-type CCK receptors possess δ opioid receptor agonist activity in vitro and in vivo: Evidence for similarities in CCK-B and δ opioid receptor requirements (1994) (8)
Neuropeptide alterations in the central nervous system in aging. (1982) (8)
A further study of the effect of propranolol on the blockade of alpha adrenergic receptors. (1969) (8)
Effects of desipramine and yohimbine on alpha 2- and beta-adrenoreceptor sensitivity. (1980) (8)
Synthesis and biological evaluation of Nα-hydroxysulfonyl-[Nle28,31]-CCK26–33 (1986) (8)
New endomorphin analogs with -agonist and -antagonist properties* (2004) (8)
Alterations in brain opiate receptors in Parkinson's disease. (1979) (8)
Autoradiographic localization of 5-HT1 receptor subtypes in rat brain. (1982) (8)
Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles. (1989) (7)
The Syrian Golden Hamster: A Model for the Cardiomyopathy of Friedreich's Ataxia (1979) (7)
Demonstration of a neurokinin A receptor subtype in transfected fibroblasts. (1992) (7)
Recent advances in muscarinic receptor heterogeneity and regulation. (1983) (7)
(2S,3R)TMT-L-Tic-OH is a potent inverse agonist at the human delta-opioid receptor. (1999) (7)
DEVELOPMENT OF AUTONOMIC RECEPTORS IN THE FETAL MOUSE HEART (1979) (7)
Examination of Cholinergic and Neuropeptide Receptor Alterations in Senile Dementia of the Alzheimer’s Type (SDAT) (1986) (7)
Kentsin: Tetrapeptide from hamster embryos produces naloxone-sensitive effects without binding to opioid receptors (1987) (7)
Brain muscarinic cholinergic receptor binding in Roman high- and low-avoidance rats (2004) (7)
Identification of B2 bradykinin binding sites in the guinea pig nasal turbinate (1989) (7)
Benzodiazepine receptors: Effect of tissue preincubation at 37°C (1979) (7)
A cloned NK2 receptor mediates phosphatidylinositol hydrolysis in a transfected murine fibroblast (1990) (7)
Multiple benzodiazepine receptors and their regulation by gamma-aminobutyric acid. (1981) (7)
Thermodynamic analyses of pirenzepine binding to membrane-bound and solubilized muscarinic receptors from rat forebrain and heart. (1987) (7)
Consequences of cis-amide bond simulation in opioid peptides (2006) (7)
A non-equilibrium 24-hour vasopressin radioimmunoassay: development and basal levels in the rat brain (1983) (7)
Dopaminergic regulation of muscarinic receptor binding in the corpus striatum. (1981) (7)
Delta opioid receptor selective ligands; DPLPE-deltorphin chimeric peptide analogues. (2009) (7)
In vitro inhibition of vasopressin release in brain by behaviorally relevant ethanol concentrations (1986) (7)
Coupling of Human δ-Opioid Receptor to Retinal Rod Transducin in Chinese Hamster Ovary Cells (2000) (7)
Molecular pharmacology of neurotransmitter receptors (1983) (7)
Opening Remarks by Prof. M. Bergener, Köln (1982) (6)
Differentiation between rat brain and mouse vas deferens delta opioid receptors. (1990) (6)
Benzomorphan alkaloids: Natural peptidomimetics of opioid peptide pharmacophores (1995) (6)
Human delta opioid receptor: a stable cell line for functional studies of opioids. (1995) (6)
Differential down-regulation of the human delta-opioid receptor by SNC80 and [D-Pen(2),D-Pen(5)]enkephalin. (2000) (6)
Cholecystokinic activity of N alpha-hydroxysulfonyl-[Nle28,31]CCK26-33 analogues modified at the C-terminal residue. (2009) (6)
Purification of [3H]taurine of high specific activity. (1977) (6)
Novel bifunctional peptides as opioid agonists and NK-1 antagonists. (2009) (6)
Temperature dependence and GABA modulation of [3H]triazolam binding in the rat brain. (1987) (6)
Spontaneous recovery of central respiratory function after an irreversible AChE inhibitor. (1972) (6)
Cyclic enkephalin analogs that are hybrids of DPDPE-related peptides and metenkephalin-Arg-Gly-Leu: prohormone analogs that retain good potency and selectivity for delta opioid receptors. (1999) (6)
Influence of chronic ethanol treatment on alpha1-adrenergic and vasopressin receptor-stimulated phosphatidylinositol synthesis in isolated rat hepatocytes. (1983) (6)
De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor. (1998) (6)
Neurokinin A receptors are coupled to calcium mobilization in transfected fibroblasts. (1991) (6)
Structural characteristics of two highly selective opioid peptides (1989) (6)
Localization of the mRNAs for Two Dopamine D2 Receptor Isoforms in the Rat Brain (1991) (5)
Cyclic enkephalin analogues with exceptional potency and selectivity for delta-opioid receptors. (1997) (5)
Quazepam, a Sedative‐Hypnotic Selective for the Benzodiazepine Type 1 Receptor: Autoradiographic Localization in Rat and Human Brain (1985) (5)
Isolation and characterization of in vitro endorphin metabolism in the brain. (1982) (5)
Novel scaffolds for non-peptide mimetics of δ opioid receptor agonists based on peptide leads (1996) (5)
Changes in opioid receptor selectivity following processing of peptide E: effect on gut motility. (1991) (5)
Para-substituted phenylalanine-4 analogues of [L-Ala3]DPDPE: highly selective delta opioid receptor ligands. (2009) (5)
Lack of Effect of Haloperidol or Methamphetamine Treatment on the mRNA Levels of Two Dopamine D, Receptor Isoforms in Rat Brain (1992) (5)
From binding studies to the molecular biology of GABA receptors (1990) (5)
Characterization of SNF 9007, a novel cholecystokinin/opoid ligand in mouse ileum in vitro: evidence for involvement of cholecystokininA and cholecystokininB receptors in regulation of ion transport. (1994) (5)
Mutation S363A in the human delta-opioid receptor selectively reduces down-regulation by a peptide agonist. (2004) (5)
Synthesis, biology, NMR and conformation studies of the topographically constrained delta-opioid selective peptide analogs of [beta-iPrPhe(3)]deltorphin I. (2001) (5)
The release in vivo of [3-H] acetylcholine from cat caudate nucleus and cerebral cortex by atropine, pentylenetetrazol, K-+ -depolarization and electrical stimulation. (1975) (5)
Ontogeny of mammalian cardiac alpha 1-adrenergic receptors. (1980) (4)
Effect of benzodiazepine binding site ligands on [35S] t-butylbicyclophosphorothionate ([35S]TBPS) binding to rat brain: an autoradiographic study. (1986) (4)
Muscarinic receptor binding in the mouse heart: the selective modulatory effect of fluoride ion on agonist binding. (1982) (4)
Biochemical Characterization of Muscarinic Cholinergic Receptors in Huntington’s Disease (1978) (4)
Appearance in cat cerebrospinal fluid of radiolabeled metabolites following intraventricular injection of [3H]choline (1974) (4)
Irreversible inhibition by tyrosine-directed alkylating reagents of muscarinic cholinergic receptors in membranes from rat forebrain and heart. (1988) (4)
[D-Pen2,D-Pen5]enkephalin (DPDPE): a delta-selective enkephalin with low affinity for mu 1 opiate binding sites. (1986) (4)
The effect of gamma-aminobutyric acid on 3H-flunitrazepam binding in rat brain. (1978) (4)
Design and Synthesis of Conformationally Constrained Somatostatin Analogues with High Potency and Specificity for μ Opioid Receptors. (1987) (4)
The synthesis and opioid receptor binding affinities of analogues of dermorphin and its N-terminal tetrapeptide fragment with dibasic acids in position 2. (1995) (4)
Opioid peptides: simultaneous delta agonism and mu antagonism in somatostatin analogues. (1997) (4)
ABNORMAL BRAIN OPIATE MECHANISMS IN SCHIZOPHRENIA (1980) (4)
Synthesis and biological properties of β‐MePhe3 analogues of deltorphin I and dermenkephalin: influence of biased X1 of Phe3 residues on peptide recognition for δ‐opioid receptors (2009) (4)
Erratum: The third extracellular loop of the human δ opioid receptor determines the selectivity of δ opioid agonist (Molecular Pharmacology (1996) 50 (1619-1624)) (1997) (4)
Design, synthesis, and biological activities of cyclic lactam peptide analogues of dynorphine A(1-11)-NH2. (1996) (4)
AUTORADIOGRAPHIC LOCALIZATION OF SUBTYPES OF MUSCARINIC AGONIST AND ANTAGONIST BINDING SITES: ALTERATIONS FOLLOWING CNS LESIONS (1986) (4)
Neuronal localization of benzodiazepine receptors in the murine cerebellum. (1981) (4)
Characterization and differential in vivo regulation of brain adrenergic receptor subtypes. (1980) (4)
Partial purification and separation of retinal acetylcholinesterase from butyrylcholinesterase by affinity chromatography. (1977) (4)
The Stereochemical Requirements of the Novel δ-Opioid Selective Dipeptide Antagonist TMT-TIC. (1998) (4)
Topographical requirements for δ opioid ligands: The synthesis and biological properties of cyclic analogues of deltorphins and dermenkephalin (1993) (3)
An increase in cardiac alpha1-adrenoceptors following chronic clonidine treatment (1982) (3)
Structural correlates for down-regulation of m1 and m2 muscarinic receptor subtypes (1998) (3)
Processing of beta-endorphin in the dog intestine: regional specificity. (1983) (3)
Structure-activity relationships of analogues of higly potent opioid peptide, biphalin (1994) (3)
Beta-carboline interactions at the BZ-GABA receptor chloride-ionophore complex in the rat cerebral cortex. (1989) (3)
Effects of chemical sympathectomy with 6-hydroxydopamine on alpha- and beta-adrenoceptors and muscarinic cholinoceptors in rat kidney. (1986) (3)
The role of the G protein gamma(2) subunit in opioid antinociception in mice. (2000) (3)
Brain Neurotransmitter Receptors in Friedreich's Ataxia (1979) (3)
Possible role of opiate receptors and des-tyrosine1-gamma-endorphin in schizophrenia. (1980) (3)
The molecular properties of the M1 muscarinic receptor and its regulation of cytosolic calcium in a eukaryotic gene expression system. (1991) (3)
β-Adrenergic receptor and adenyl cyclase development in the mouse heart (1980) (3)
A Procedure for the Microdetermination of Choline Acetyltransferase (1972) (3)
A study of the metabolism of des-tyrosine-gamma-endorphin using an improved HPLC system. (1982) (3)
Antinociception depends on the presence of G protein gamma2-subunits in brain. (2005) (3)
Effect of Guanidino Compounds on GABA-Stimulated Chloride Influx into Membrane Vesicles from Rat Cerebral Cortex (1989) (3)
Sustained cannabinoid agonist treatment augments CGRP release in a PKA-dependent manner (2009) (3)
The efficacy of delta-opioid receptor-selective drugs. (1998) (3)
Psychopharmacology and biochemistry of neurotransmitter receptors : proceedings of an international conference held on April 11-13, 1980, in Tucson, Arizona, U.S.A. (1980) (3)
Amino acids with amphiphilic side chains: Deltorphin analogues with Phe3 replaced by all β-hydroxyphenylalanine diastereoisomers (1995) (3)
Regulation of Muscarinic Receptor Binding (1981) (3)
Synthesis of [D-Ala2,4'-125I-Phe3,Glu4]deltorphin and characterization of its delta opioid receptor binding properties. (1992) (3)
Use of autoradiographic techniques for the localization of neurotransmitter receptors in brain and periphery: recent applications. (1984) (3)
Biological properties of Phe(o)-opioid peptide analogues. (2001) (3)
The role of the Val353 residue in antagonist binding to rat CCK-B receptors. (1995) (3)
Specific high-affinity [3H]Ro5-4864 Ro5-4864 benzodiazepine binding sites in the brain and periphery. (1985) (3)
Alterations in brain muscarinic cholinergic receptor binding and choline acetyltransferase activity in Huntington's disease. (1976) (3)
DESIGN AND SYNTHESIS OF PEPTIDE LIGANDS WITH UNIQUE BIOCHEMICAL AND BIOLOGICAL PROFILES AT OPIOID RECEPTORS THAT CROSS THE BLOOD BRAIN BARRIER (1995) (3)
Topographical requirements for δ-opioid ligands: The synthesis and biological properties of β-MePhe containing deltorphin I and dermenkephalin analogs (1993) (3)
DESIGN AND SYNTHESIS OF RECEPTOR SELECTIVE PEPTIDE NEUROTRANSMITTERS (1987) (2)
Biochemical demonstration of muscarinic cholinergic receptors in mammalian heart (1977) (2)
Allosteric modulation by diltiazem and verapamil of [3H]nitrendipine binding to calcium channel sites in rat brain. (1983) (2)
DEMONSTRATION OF PLACENTAL ENDORPHINS BY RADIOIMMUNOASSAY AND RADIORECEPTOR TECHNIQUES (1980) (2)
The effect of GABA on the binding of 3H-flunitrazepam in mouse brains during development (1979) (2)
Amino acids, peptides and benzodiazepines (1980) (2)
Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. (1982) (2)
Huntington's disease: Alterations in GABA and benzodiazepine receptors in the human brain (1980) (2)
Synthesis and biological activities of linear and cyclic enkephalin analogs containing a Gly3 Ψ(E,CH = CH)Phe4 replacement (1990) (2)
Cholinergic receptors in the mammalian central nervous system. (1976) (2)
Characterization of kappa opioid receptors in the rabbit ear artery. (1988) (2)
The benzodiazepine receptor: complex binding properties and the influence of GABA. (1983) (2)
A comparison of the effects of cinnarizine and related compounds on [3H]nitrendipine binding in the brain, heart and ileum. (1984) (2)
Presynaptic muscarinic cholinergic and postsynaptic beta-adrenergic receptors in splenic tissue. (1983) (2)
Effect of Kainic Acid Lesions on Taurine Transport into Rat Brain Synaptosomes (1981) (2)
Coupling of human delta-opioid receptor to retinal rod transducin in Chinese hamster ovary cells. (2000) (2)
Recovery of cholinesterase activity in the cerebrospinal fluid, brainstem and plasma of the unanesthetized cat after irreversible cholinesterase inhibition (2005) (2)
Delta opioid receptor selective ligands; DPLPE-deltorphin chimeric peptide analogues. (1994) (1)
Modulation of benzodiazepine receptor binding by antiepileptic drugs and seizures. (1981) (1)
2329 – BIOCHEMICAL CHARACTERIZATION OF 3H-FLUNITRAZEPAM BINDING TO BENZODIAZEPINE RECEPTORS IN THE RAT BRAIN (1978) (1)
Identification of the structural elements responsible for high biological activity of dimeric opioid peptide biphalin (1999) (1)
Myocardial muscarinic cholinergic receptors (1977) (1)
Cationized deltorphin analogues: Potent and selective ligands for delta opiate receptors (1994) (1)
[N-methylnorleucine-(28,31)]cholecystokinin-(26-33) (SNF 8702) activity at a cloned rat CCKB receptor. (1994) (1)
Identification of calcium-channel receptors in intact animals. (1985) (1)
Muscarinic cholinergic receptor binding in mammalian central and peripheral nervous system: demonstration in vitro and in vivo (1974) (1)
Molecular organization of receptors. Efficacy, agonists, and antagonists. (1995) (1)
Mechanisms of cardiac arrhythmias: Muscarinic cholinergic receptor alterations in the production of asystole (1979) (1)
CONFORMATIONALLY RESTRICTED TRICYCLIC ANTIDEPRESSANTS. 1. OCTAHYDRODIBENZAZEPINONAPHTHYRIDINES AS RIGID IMIPRAMINE ANALOGS (1981) (1)
Relative stability of alpha-melanotropin and related analogues to rat brain homogenates. (1984) (1)
Role of Substance P in the Regulation of Ion Transport by CCKA and CCKB Receptors in Mouse Ileum (1994) (1)
Desensitization of neurokinin A receptors expressed by B82 fibroblasts. (1993) (1)
Research report Improved bioavailability to the brain of glycosylated Met-enkephalin (2000) (1)
Novel scaffolds for non-peptide mimetics of delta opioid receptor agonists based on peptide leads. (1996) (1)
Designing peptides with specific conformational, topographical and biological properties (1993) (1)
DEMONSTRATION OF BZD-1 RECEPTOR SPECIFIC BENZODIAZEPINES USING AUTRADIOGRAPHIC TECHNIQUES (1984) (1)
Design of peptides and peptidomimetics for delta and kappa opioid receptor subtypes (1994) (1)
Pharmacological and molecular basis for reclassifying peripheral-type benzodiazepine receptors as τ (tau) receptors (1991) (1)
[3H] SNF 8702 Autoradiography of CCK‐B Receptors in Guinea Pig Brain and Studies with a Cloned Rat CCK‐B Receptor (1994) (1)
(2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain. (2003) (1)
A radioreceptor assay for estimation of acetylcholine. (1982) (1)
Design, synthesis and conformation in chi space for developing selective peptides for types and subtypes of receptors (1995) (1)
New opioid compounds in analgesia (1994) (1)
[125I]SNF 8702: A selective radioligand for CCKB receptors (1995) (1)
Synthesis and biological properties of beta-MePhe3 analogues of deltorphin I and dermenkephalin: influence of biased chi 1 Phe3 residues on peptide recognition for delta-opioid receptors. (1997) (1)
Erratum: Direct observation of G-protein binding to the human δ-opioid receptor using plasmon-waveguide resonance spectroscopy (Journal of Biological Chemistry (2003) 278 (48890-48897)) (2005) (1)
Pseudoirreversible binding characteristics of [D-Ala2,Glu4]deltorphin and its Cys4 substituted derivative to delta-opioid receptors. (1993) (1)
EFFECTS OF ANXIOLYTIC DRUGS ON CLONED RAT SEROTONIN1A RECEPTOR EXPRESSED IN CULTURED CELLS. (1992) (0)
Designing peptidomimetic antagonists for peptide receptors: topochemical differences of agonists and antagonists (1999) (0)
Correlation between pharmacological activity and the influence of GABA on the binding of flunitrazepam and the specific benzodiazepine antagonist, Ro 15-1788 (1982) (0)
Brain Acetylcholinesterase: Solubilization and Partial Purification by Affinity Chromatography. (1972) (0)
CONFORMATIONALLY RESTRICTED PHENOTHIAZINE NEUROLEPTICS. 1. 3-(DIMETHYLAMINO)-1,2,3,4-TETRAHYDROAZEPINO(3,2,1-KL)PHENOTHIAZINE (1981) (0)
The effect of GABA on the binding of [3H]flunitrazepam in mouse brains during development (1979) (0)
Inverse agonism at the delta opioid receptors (2003) (0)
Inhibition of in vivo 3H-spiperone binding by the proposed antipsychotic Des-Tyr1-gamma-endorphin. (1979) (0)
CNS Receptors for Opioids (2017) (0)
High affinity specific [3H](+)PN 200-110 binding to a dihydropyridine receptor calcium channel complex in rat heart and cerebral cortex (1984) (0)
Topographic model of delta opioid selective ligands; DPLPE-deltorphin hybrid analogues (1994) (0)
Bnezodiazepine Benzodiazepine binding using [3H]propyl β-carboline-3-carboxylate (1981) (0)
SNC80 specific down-regulation of the human δ-opioid receptor (hDOR) truncated at Gly338 (2000) (0)
The synthesis and opioid receptor binding affinities of dermorphin and deltorphin analogs with dibasic amino acids in position 2 (1993) (0)
Chemical neurotoxins as tools to model CNS disease states (1984) (0)
Use of a potent and selective highly constrained peptide agonist to design de novo an equally potent and selective non-peptide mimetic for the δ-Opioid receptor (2002) (0)
Erratum: Delta opioid receptor selective ligands; DPLPE-deltorphin chimeric peptide analogues (International Journal of Peptide and Protein Research Vol. 44 (1994) (80-84)) (1994) (0)
Recent advances in the neurochemistry of Huntington's disease. (1977) (0)
The fine tuning of high affinity and selective non-peptide agonists of the δ-opioid receptor via solution and solid-phase (2002) (0)
Probes for narcotic receptor-mediated phenomena. 25. Synthesis and evaluation of N-alkyl-substituted (alpha-piperazinylbenzyl)benzamides as novel, highly selective delta opioid receptor agonists. (1997) (0)
Cholinergic Muscarinic Receptor : Biochemical and Light Autoradiographic Localization in the Brain (2018) (0)
Synthesis and biological evaluation of N alpha-hydroxysulfonyl-[Nle28,31]-CCK26-33. (1986) (0)
1501 – STUDIES ON THE SOLUBILIZATION OF RECEPTOR PROTEINS FROM CHOLINERGIC MEMBRANES (1977) (0)
[3H]Pirenzepine and [3H](-)quinuclidinylbenzilate binding to putative M1 And M2 muscarinic sites in deoxycorticosterone-NACL hypertensive rats (1985) (0)
Characterization of muscarinic receptors on intact human neuroblastoma cells: coupling to phosphoinositide hydrolysis and phosphorylation by phorbol esters (1986) (0)
Topographically designed analogues of c[d-Pen2, Pen5, Nle6] deltorphin I with stereoisomers of β-MePhe or β-iPrPhe in position 3 (1999) (0)
Heterogeneity of tachykinin receptors in the rabbit lung (1996) (0)
Tricyclic antidepressants and the central cholinergic muscarinic receptor (1975) (0)
Selective affinity of pirenzepine analogues for subtypes of muscarinic receptors (1986) (0)
Modification of the address sequence of dynorphin A that produces highly potent δ-selective peptide agonists (1994) (0)
Pharmacological comparison of the cloned rat and human M2 muscarinic receptor genes expressed in the murine fibroblast (B82) cell line (1993) (0)
Alterations in benzodiazepine receptors in cerebella of mutant mice. Abstr. (1979) (0)
Characterization of high affinity (/sup 3/H)triazolam binding in rat brain (1986) (0)
Benzodiazepine receptors: effect of tissue preincubation at 37 degrees C. (1979) (0)
Short communication Mutation S363A in the human y-opioid receptor selectively reduces down-regulation by a peptide agonist (2004) (0)
Structure-function relationships of new synthetic CCK/sub 8/ analogs in rat brain and pancreas (1986) (0)
CHARACTERIZATION OF [3H]SPIROPERIDOL BINDING IN THE RAT SUBSTANTIA NIGRA (1979) (0)
Design and synthesis of nanomolar δ-opioid selective nonpeptide mimetic agonists based on peptide leads (2002) (0)
The selective regulatory effect of fluoride ion on muscarinic agonist binding in mouse myocardium (1982) (0)
Constrainedδ opioid peptides: Analogs of DPDPE and deltorphin I containing trimethylphenylalanine instead of phenylalanine (2002) (0)
Complex binding properties of the benzodiazepine receptor (1982) (0)
Demonstration and partial characterization of a bovine cerebral cortical factor which interacts competitively at the benzodiazepine receptor. (1983) (0)
Cisternal Drainage, Ventriculo-Aqueductal Perfusion Techniques, and Their Application in Research Related to Brain Chemistry. (1975) (0)
Erratum: Selectivity, cooperativity, and reciprocity in the interactions between the δ-opioid receptor, its ligands, and G-proteins (Journal of Biological Chemistry (2004) 279 (44673-44682)) (2005) (0)
Post-synaptic β-adrenergic receptors increase and pre-synaptic muscarinic receptors decrease in splenic tissue after 6-hydroxydopamine treatment (1981) (0)
Expression of dopamine D2 receptor and kainate receptor mRNAs in the phencyclidine treated rat brain (1991) (0)
Surprisingly potent and selective 3-position analogs of DPDPE for the δ opioid receptor (1993) (0)
Postnatal development and regulation of the muscarinic receptor in the mouse heart using the agonist [3H]CIS methyldioxolane (1981) (0)
Light Microscopic Localization of Drug and Neurotransmitter Receptors in the Brain (1990) (0)
Topographical design of message domain pharmacophores of δ opioid agonists provide insights into the stereochemical requirements for recognizing δ opioid receptor subtypes (1995) (0)
Heterogeneity of neurotransmitter receptors (1990) (0)
Coupling of Human d -Opioid Receptor to Retinal Rod Transducin in Chinese Hamster Ovary Cells 1 (1999) (0)
Identification of Putative M1 Muscarinic Receptors Using [3H]Pirenzepine: Characterization of Binding and Autoradiographic Localization in Human Stellate Ganglia (1986) (0)
Peptides in sensory nerves. (1982) (0)
Antagonist affinity states of cardiac α-adrenoceptors and their regulation (1982) (0)
Studies on (/sup 3/H) hemicholinium-3 ((/sup 3/H)HC-3), (/sup 3/H) pirenzepine ((/sup 3/H)PZ) and (/sup 3/H)(-)quinuclidinyl benzilate ((/sup 3/H)(-)QNB) binding with choline and acetylcholine analogues (AF30, AF64, AF64A) (1986) (0)
Kinetic Evidence for a Unique High Affinity Uptake System for Choline in Rat Brain Synaptosomes. (1973) (0)
Cardiac calcium antagonist channels labelled by [3H]nitrendepine: Characterization, drug and ionic specificity (1982) (0)
Conversion of somatostatin to an opioid peptide: design using a conformational template and topographical constraints (1990) (0)
Potent cyclic enkephalin analogues for delta opioid receptors in the rat brain (1986) (0)
Radioimmunoassay of vasopressin: development and application to the measurement of intra- and extra-hypothalamic vasopressin levels in the rat. (1982) (0)
Cloning, expression and pharmacological characterization of a human delta opioid receptor: 26.6 (1995) (0)
Characterization of cardiac α1-adrenergic receptors by [3H]WB4101 and alteration following chemical sympathectomy (1981) (0)
Identification in vivo of muscarinic cholinergic receptor binding in rat brain (1974) (0)
Guanidino cationization effects on the blood-brain barrier permeability, in vitro stability and receptor binding of endomorphins (1999) (0)
Consequences of Cis-amide Bond Simulation in Opioid Peptides (2004) (0)
Second Messenger Activators Regulate CCK mRNA in the Human Neuroepithelioma Cell Line SK‐N‐MCIXC a (1994) (0)
Structure-function correlation of muscarinic acetylfholine receptors (1992) (0)
Design of a δ opioid peptide mimetic based on a topographically constrained cyclic enkephalin (2002) (0)
Cloning and Expression of the Human Delta Opioid Receptor (2003) (0)
Muscarinic cholinergic receptor binding in mammalian central and peripheral nervous system with (3H) quinuclidinyl benzilate (1974) (0)
A further study of the antagonistic action between alpha and beta blocking agents. (1968) (0)
Studies of Spontaneous Recovery of Central Respiratory Function after Acetylcholinesterase Inhibition by Organophosphates. (1973) (0)
Muscarinic cholinergic receptor-mediated regulation of isoproterenol stimulated cyclic AMP formation in rat cardiomyocytes (1985) (0)
A novel triazolopyridazine, [3H]CL 218,872 which labels the benzodiazepine receptor in rat brain (1982) (0)
Solubilized musarinic recognition sites from rat brain and heart: evidence in favor of a homogeneous population of sites (1986) (0)
Benzodiazepine receptors in animal models of cerebellar degeneration. (1979) (0)
The role of the dorsal mesencephalic reticular formation and deep layers of the superior colliculus in the turning behavior originating from the corpus striatum. (1982) (0)
Development of Models for the Bioactive Conformations of Ligands for CCK A and B Receptors and Their Use in the Design and Synthesis of Highly Potent and Selective Analogs (1992) (0)
Synthesis, opioid activities and binding affinities of dynorphin A analogues with position-3 conformational constraints: New insights into requirements for κ receptors (1995) (0)
Cardiac muscarinic receptors: Regulation of the agonist binding using the ligand [3H]-cismethyldioxolane (CD) (1980) (0)
Pharmacologic comparison of the cloned M1 and M2 muscarinic receptors of the rat expressed in murine fibroblast cells (1990) (0)
Understanding BBB Transport using Glycosylated Enkephalins and Endorphins (2006) (0)
The GABA shift: A predictor of anxiolytic efficacy (1982) (0)
Conformationally Restricted Cyclic Penicillamine Analogues with High Selectivity for δ- and μ-Opioid Receptors (1986) (0)
Design of Peptides and Peptidomimetics That Are Selective, Stable and Can Cross Membrane Barriers (1997) (0)
Practical glycopeptide analgesics: Blood-brain barrier transport and binding of glycosylated enkephalin analogs (2002) (0)
L-histidine: high affinity transport into rat brain synaptosomes. (1976) (0)
Regulation of (-)epinephrine high affinity state of (β-adrenoceptors in the rat heart left ventricles (1983) (0)
Changes of the mRNAs for two dopamine D2 receptor isoforms in rat brain by haloperidol or methamphetamine treatment (1991) (0)
N-terminal cyclization of a nonsulfated CCK analogue exhibits opioid antagonist activity in vitro. (1987) (0)
Alterations in central and peripheral receptors (R) in salt deoxycorticosterone (DOCA) treated rats (1980) (0)
α-Helical Glycopeptide Analgesics: β-Endorphin Mimics with Good in vivo Potency (2001) (0)
Title Page / Table of Contents, Vol. 28, Supplement 1, 1982 (1982) (0)
Choline: High Affinity Transport into Synaptosomes of Rat Brain. (1974) (0)
Characterization of NK-2 binding sites in rabbit lung tissue (1992) (0)
Characterization of NK-2 binding sites in rabbit lung tissue (1992) (0)

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