Harihara M. Mehendale
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(Suggest an Edit or Addition)Harihara M. Mehendale's Published Works
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Published Works
- Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. (2007) (639)
- Volatile Organic Compounds (2014) (318)
- Tissue Repair: An Important Determinant of Final Outcome of Toxicant-Induced Injury (2005) (223)
- Cationic amphiphilic drugs and phospholipid storage disorder. (1990) (196)
- Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and β-catenin signaling (2010) (153)
- SATURATION TOXICOKINETICS OF THIOACETAMIDE: ROLE IN INITIATION OF LIVER INJURY (2005) (143)
- Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1. (2000) (138)
- Potentiation of the hepatotoxicity of carbon tetrachloride following preexposure to chlordecone (kepone) in the male rat. (1979) (120)
- Mimetics of Caloric Restriction Include Agonists of Lipid-activated Nuclear Receptors* (2004) (118)
- Tissue repair response as a function of dose in thioacetamide hepatotoxicity. (1995) (117)
- Novel mechanisms in chemically induced hepatotoxicity 1 (1994) (114)
- Cytochrome P4502E1 induction increases thioacetamide liver injury in diet-restricted rats. (2001) (112)
- Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants. (2003) (109)
- Chronic Ethanol Intake Impairs Insulin Signaling in Rats by Disrupting Akt Association with the Cell Membrane (2006) (105)
- Tissue injury and repair as parallel and opposing responses to CCl4 hepatotoxicity: a novel dose-response. (1997) (101)
- Protection of Hepatotoxic and Lethal Effects of CCl by Partial Hepatectomy (1989) (99)
- Metabolism and effects of hexachlorobenzene on hepatic microsomal enzymes in the rat. (1975) (91)
- Stimulated hepatic tissue repair underlies heteroprotection by thioacetamide against acetaminophen‐induced lethality (1995) (90)
- Role of hepatocellular regeneration and hepatolobular healing in the final outcome of liver injury. A two-stage model of toxicity. (1991) (89)
- Renal and hepatic transporter expression in type 2 diabetic rats. (2008) (88)
- Role of Hepatocellular Regeneration in CCl4 Autoprotection (1991) (83)
- Potentiation of CCl4 lethality by chlordecone. (1982) (78)
- Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a morphometric and biochemical study. (1983) (77)
- Calpain: a death protein that mediates progression of liver injury. (2005) (77)
- The isolated perfused lung--a critical evaluation. (1981) (75)
- Fate of mirex-14C in the rat and plants (1972) (73)
- Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a light and electron microscopic study. (1983) (73)
- NTP-CERHR expert panel report on the reproductive and developmental toxicity of hydroxyurea. (2007) (73)
- Potentiation of halomethane hepatotoxicity: chlordecone and carbon tetrachloride. (1984) (70)
- Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats. (2000) (70)
- Toxicokinetics and toxicity of thioacetamide sulfoxide: a metabolite of thioacetamide. (2007) (67)
- Types of interaction of amphiphilic drugs with phospholipid vesicles. (1988) (63)
- Type 1 diabetic mice are protected from acetaminophen hepatotoxicity. (2003) (63)
- Mechanisms and Outcomes of Drug- and Toxicant-Induced Liver Toxicity in Diabetes (2007) (63)
- Specificity of chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity. (1980) (61)
- Hepatocellular regeneration: key to thioacetamide autoprotection. (1995) (61)
- Nonalcoholic fatty liver sensitizes rats to carbon tetrachloride hepatotoxicity (2007) (60)
- Activation of PPAR‐α in streptozotocin‐induced diabetes is essential for resistance against acetaminophen toxicity (2003) (60)
- Potentiation of Carbon Tetrachloride Hepatotoxicity and Lethality in Type 2 Diabetic Rats (2004) (59)
- Potentiation of CCl4 hepatotoxicity and lethality by chlordecone in female rats. (1983) (57)
- Fluorescence studies on binding of amphiphilic drugs to isolated lamellar bodies: relevance to phospholipidosis. (1989) (56)
- Effects of blockade of Kupffer cells by gadolinium chloride on hepatobiliary function in cold ischemia‐reperfusion injury of rat liver (1997) (55)
- Effects of hexachlorobutadiene (HCBD) on renal function and renal organic ion transport in the rat. (1979) (54)
- Functional and biochemical correlates of chlordecone exposure and its enhancement of CCl4 hepatotoxicity. (1980) (53)
- Effects of kepone and mirex on mitochondrial Mg2+-ATPase activity in rat liver. (1977) (53)
- Amplified interactive toxicity of chemicals at nontoxic levels: mechanistic considerations and implications to public health. (1994) (52)
- Kepone induction of hepatic mixed function oxidases in the male rat. (1977) (49)
- In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital. (1988) (49)
- Benzo[a]pyrene. (1983) (49)
- Potentiation of CCl4 and CHCl3 hepatotoxicity and lethality by various alcohols. (1990) (49)
- High fat diet-fed obese rats are highly sensitive to doxorubicin-induced cardiotoxicity. (2008) (49)
- Upregulation of calpastatin in regenerating and developing rat liver: Role in resistance against hepatotoxicity (2006) (48)
- Upregulated promitogenic signaling via cytokines and growth factors: potential mechanism of robust liver tissue repair in calorie-restricted rats upon toxic challenge. (2002) (47)
- Nutritional impact on the final outcome of liver injury inflicted by model hepatotoxicants: effect of glucose loading (1995) (47)
- Colchicine Antimitosis Abolishes CCl4 Autoprotection (1991) (46)
- PPAR-α: A Key to the Mechanism of Hepatoprotection by Clofibrate (2000) (45)
- Mechanisms of increased liver tissue repair and survival in diet-restricted rats treated with equitoxic doses of thioacetamide. (2003) (45)
- Renal injury and repair following S-1, 2 dichlorovinyl-L-cysteine administration to mice. (2003) (44)
- Autoprotection: stimulated tissue repair permits recovery from injury. (1994) (44)
- Effect of an antimitotic agent colchicine on thioacetamide hepatotoxicity. (1996) (44)
- Mechanism of protection of moderately diet restricted rats against doxorubicin-induced acute cardiotoxicity. (2007) (43)
- Pulmonary sequestration of amiodarone and desethylamiodarone. (1986) (43)
- Role of tissue repair in toxicologic interactions among hepatotoxic organics. (1998) (43)
- Potentiation of halomethane hepatotoxicity by chlordecone: a hypothesis for the mechanism. (1990) (43)
- Hepatic microsomal metabolism of CCL4 after pretreatment with chlordecone, mirex, or phenobarbital in male rats. (1983) (42)
- Mechanism of the lethal interaction of chlordecone and CCl4 at non-toxic doses. (1989) (42)
- Acute hepatotoxicity and lethality of CCl4 in chlordecone-pretreated rats. (1983) (42)
- Effect of preexposure to kepone on the biliary excretion of imipramine and sulfobromophthalein. (1977) (42)
- Protective role of fructose 1,6-bisphosphate during CCl4 hepatotoxicity in rats. (1989) (42)
- Diet restriction enhances compensatory liver tissue repair and survival following administration of lethal dose of thioacetamide. (1998) (41)
- Suppression of cellular immune responses in BALB/c mice following oral exposure to permethrin (1995) (40)
- Hepatic cell division and tissue repair: a key to survival after liver injury. (1996) (40)
- G2 subpopulation in rat liver induced into mitosis by low-level exposure to carbon tetrachloride: an adaptive response. (1993) (39)
- Inhibition of mouse brain synaptosomal ATPases and ouabain binding by chlordecone. (1980) (39)
- The effects of kepone pretreatment on biliary excretion of xenobiotics in the male rat. (1979) (39)
- Accumulation of Ca2+ induced by cytotoxic levels of menadione in the isolated, perfused rat liver. (1985) (39)
- Role of tissue repair in survival from s-(1,2-dichlorovinyl)-L-cysteine-induced acute renal tubular necrosis in the mouse. (2003) (38)
- Streptozotocin-induced diabetic mice are resistant to lethal effects of thioacetamide hepatotoxicity. (2003) (38)
- Toxicant-inflicted injury and stimulated tissue repair are opposing toxicodynamic forces in predictive toxicology. (1999) (38)
- Inhibition of mitochondrial Mg2+ ATPase activity in isolated perfused rat liver by kepone. (1977) (38)
- Role of nutritional fatty acid and L‐carnitine in the final outcome of thioacetamide hepatotoxicity 1 (1994) (37)
- Effect of mirex on the activities of various rat hepatic mixed-function oxidases (1973) (37)
- Disposition and nephrotoxicity of hexachloro-1,3-butadiene. (1980) (37)
- A review of the role of tissue repair as an adaptive strategy: why low doses are often non-toxic and why high doses can be fatal. (1996) (36)
- Physiologically based pharmacokinetic/pharmacodynamic modeling of the toxicologic interaction between carbon tetrachloride and Kepone (1996) (36)
- Stimulated tissue repair prevents lethality in isopropanol-induced potentiation of carbon tetrachloride hepatotoxicity. (1996) (35)
- Toxicodynamics of low level toxicant interactions of biological significance: inhibition of tissue repair. (1995) (35)
- Glutathione metabolism and utilization of external thiols by cigarette smoke-challenged, isolated rat and rabbit lungs. (1988) (35)
- Amplification of Chloroform Hepatotoxicity and Lethality by Dietary Chlordecone (Kepone®) in Mice (1988) (34)
- Ultrastructural and biochemical correlates of the specificity of chlordecone-potentiated carbon tetrachloride hepatotoxicity. (1981) (34)
- Effect of colchicine on hepatobiliary function in CCl4 treated rats. (1991) (34)
- Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality. (2001) (33)
- Lethal effects of CCl4 and its metabolism by Mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex. (1990) (32)
- In vitro metabolism of amiodarone by rabbit and rat liver and small intestine. (1986) (32)
- Chlordecone (kepone®)‐potentiated carbon tetrachloride hepatotoxicity in partially hepatectomized rats — a histomorphometric study (1989) (32)
- Molecular Mechanisms of Renal Tissue Repair in Survival from Acute Renal Tubule Necrosis: Role of ERK1/2 Pathway (2003) (32)
- Potentiation of brominated halomethane hepatotoxicity by chlordecone in the male rat. (1981) (32)
- Uptake and disposition of chlorinated biphenyls by isolated perfused rat liver. (1976) (31)
- Metabolism of chlorpromazine by pulmonary microsomal enzymes in the rat and rabbit. (1982) (31)
- Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital. (2007) (31)
- Antimitotic intervention with colchicine alters the outcome of o-DCB-induced hepatotoxicity in Fischer 344 rats. (1997) (31)
- Hepatobiliary dysfunction and inhibition of adenosine triphosphatase activity in bile canaliculi-enriched fractions following in vivo mirex, photomirex, and chlordecone exposures. (1981) (31)
- Role of nutrition in the survival after hepatotoxic injury. (1996) (30)
- Efficient tissue repair underlies the resiliency of postnatally developing rats to chlordecone + CCl4 hepatotoxicity. (1996) (30)
- Temporal changes in tissue repair permit survival of diet-restricted rats from an acute lethal dose of thioacetamide. (1998) (30)
- Pivotal Role of Hepatocellular Regeneration in the Ultimate Hepatotoxicity of CCl 4 in Chlordecone-, Mirex-, or Phenobarbital-Pretreated Rats (1992) (29)
- Adenosine triphosphate protection of chlordecone-amplified CCl4 hepatotoxicity and lethality. (1994) (29)
- The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity. (1989) (29)
- Mirex-induced suppression of biliary excretion of polychlorinated biphenyl compounds. (1976) (29)
- Two-dimensional electrophoretic analysis of compartment-specific hepatic protein charge modification induced by thioacetamide exposure in rats. (1996) (28)
- Effect of preexposure to kepone on hepatic mixed-function oxidases in the female rat. (1978) (28)
- Protection from CCl4 toxicity by prestimulation of hepatocellular regeneration in partially hepatectomized gerbils. (1991) (28)
- Strain differences in tissue repair response to 1,2-dichlorobenzene (1996) (28)
- Altered hepatic energy status in chlordecone (Kepone)-potentiated CCl4 hepatotoxicity. (1990) (27)
- Protective Effect of Type 2 Diabetes on Acetaminophen-Induced Hepatotoxicity in Male Swiss-Webster Mice (2006) (27)
- Impact of repeated exposure on toxicity of perchloroethylene in Swiss Webster mice. (2007) (27)
- Diet Restriction as a Protective Mechanism in Noncancer Toxicity Outcomes: A Review (2000) (27)
- Nonalcoholic steatohepatitic (NASH) mice are protected from higher hepatotoxicity of acetaminophen upon induction of PPARalpha with clofibrate. (2008) (27)
- Effect of chlordecone on carbon tetrachloride-induced increase in calcium uptake in isolated perfused rat liver. (1986) (26)
- Secretory phospholipase A2 mediates progression of acute liver injury in the absence of sufficient cyclooxygenase-2. (2008) (26)
- Effects of chlorphentermine and phentermine on the pulmonary disposition of 5-hydroxytryptamine in the rat in vivo. (1983) (26)
- Resiliency to Amplification of Carbon Tetrachloride Hepatotoxicity by Chlordecone during Postnatal Development in Rats (1993) (26)
- Amiodarone- and desethylamiodarone-induced pulmonary phospholipidosis, inhibition of phospholipases in vivo, and alteration of [14C]amiodarone uptake by perfused lung. (1991) (26)
- CCl4-induced alterations in Ca++ homeostasis in chlordecone and phenobarbital pretreated animals. (1984) (26)
- Studies on the age-dependent effects of galactosamine in primary rat hepatocyte cultures. (1991) (25)
- Mirex-induced impairment of hepatobiliary function. Suppressed biliary excretion of imipramine and sulfobromophthalein. (1977) (25)
- Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury. (2008) (25)
- Excessive hepatic accumulation of intracellular Ca2+ in chlordecone potentiated CCl4 toxicity. (1984) (25)
- Species differences in pulmonary N-oxidation of chlorpromazine and imipramine. (1984) (25)
- Potentiation of bromotrichloromethane hepatotoxicity and lethality by chlordecone preexposure in the rat. (1982) (25)
- Type 2 diabetic rats are sensitive to thioacetamide hepatotoxicity. (2006) (25)
- Extent and Timeliness of Tissue Repair Determines the Dose-Related Hepatotoxicity of Chloroform (2003) (24)
- Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture. (2003) (24)
- Carbon tetrachloride metabolism in partially hepatectomized and sham-operated rats pre-exposed to chlordecone (Kepone). (1989) (24)
- Molecular mechanisms of enhanced renal cell division in protection against S-1,2-dichlorovinyl-L-cysteine-induced acute renal failure and death. (2005) (24)
- Effects of oral administration of chlordecone and mirex on brain biogenic amines in mice. (1982) (24)
- Destruction of hepatic mixed-function oxygenase parameters by CCl4 in rats following acute treatment with chlordecone, Mirex, and phenobarbital. (1983) (23)
- Effect of Phenobarbital and Mirex Pretreatments on CCl4 Autoprotection (1994) (23)
- Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality. (1998) (23)
- Phenobarbital-induced cytosolic cytoprotective mechanisms that offset increases in NADPH cytochrome P450 reductase activity in menadione-mediated cytotoxicity. (1989) (23)
- Protection from chlordecone-amplified carbon tetrachloride toxicity by cyanidanol: biochemical and histological studies. (1991) (23)
- Effect of two isomeric tetrachlorobiphenyls on rats and their hepatic enzymes (1973) (23)
- In vivo toxicity and pulmonary effects of promazine and chlorpromazine in rats. (1990) (22)
- Hepatic uptake and disposition of aflatoxin B1 in isolated perfused rat liver. (1977) (22)
- Effect of amiodarone on Na+‐, K+‐ATPase and Mg2+‐ATPase activities in rat brain synaptosomes (1986) (21)
- Carbon tetrachloride—induced alterations of hepatic calmodulin and free calcium levels in rats pretreated with chlordecone (1991) (20)
- Age-related differences in TGF-alpha and proto-oncogenes expression in rat liver after a low dose of carbon tetrachloride. (1995) (20)
- Protection from chlordecone-amplified carbon tetrachloride toxicity by cyanidanol: regeneration studies. (1991) (20)
- Preplaced cell division: a critical mechanism of autoprotection against S-1,2-dichlorovinyl-L-cysteine-induced acute renal failure and death in mice. (2006) (19)
- 13 – Mechanism of the Interactive Amplification of Halomethane Hepatotoxicity and Lethality by Other Chemicals (1994) (19)
- Tolerance of aged Fischer 344 rats against chlordecone-amplified carbon tetrachloride toxicity (2004) (19)
- Dietary choline requirements, phospholipids and development in Phormia regina (1969) (19)
- Glucuronidation mechanisms in the rat and their significance in the metabolism of insecticides (1971) (19)
- Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride. (1993) (18)
- Stimulated pulmonary cell hyperplasia underlies resistance to α-naphthylthiourea (2000) (18)
- Biliary excretory dysfunction following exposure to photomirex and photomirex/carbon tetrachloride combination. (1979) (18)
- Secretory phospholipase A₂-mediated progression of hepatotoxicity initiated by acetaminophen is exacerbated in the absence of hepatic COX-2. (2011) (18)
- PPAR-alpha: a key to the mechanism of hepatoprotection by clofibrate. (2000) (18)
- N-oxidation of imipramine by isolated perfused rat and rabbit lung. (1980) (18)
- Dose-Dependent Modulation of Cell Death: Apoptosis Versus Necrosis in Thioacetamide Hepatotoxicity (1998) (18)
- Protection from chlordecone (Kepone)-potentiated CCl4 hepatotoxicity in rats by fructose 1,6-diphosphate. (1989) (18)
- Comparative changes in hepatic DNA, RNA, protein, lipid, and glycogen induced by a subtoxic dose of CCl4 in chlordecone, mirex, and phenobarbital pretreated rats. (1987) (17)
- Chlorphentermine uptake by isolated perfused rabbit lung. (1980) (17)
- 2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis (2009) (17)
- Effect of cytochrome P-450 and flavin-containing monooxygenase modifying factors on the in vitro metabolism of amiodarone by rat and rabbit. (1987) (17)
- Proteomics of S-(1, 2-dichlorovinyl)-L-cysteine-induced acute renal failure and autoprotection in mice. (2007) (16)
- Fetal alcohol spectrum disorders. (2023) (16)
- PB-PK derived metabolic constants, hepatotoxicity, and lethality of BrCCl3 in rats pretreated with chlordecone, phenobarbital, or mirex. (1991) (16)
- In vitro glucosylation of 1-naphthol by insects (1972) (16)
- Hepatic polyamines and related enzymes following chlordecone-potentiated carbon tetrachloride toxicity in rats. (1989) (16)
- Age-Related Susceptibility to Chlordecone-Potentiated Carbon Tetrachloride Hepatotoxicity and Lethality Is Due to Hepatic Quiescence (1995) (16)
- Diabetic mice are protected from normally lethal nephrotoxicity of S-1,2-dichlorovinyl-L-cysteine (DCVC): role of nephrogenic tissue repair. (2006) (16)
- Nutritional modulation of the final outcome of hepatotoxic injury by energy substrates: an hypothesis for the mechanism. (1996) (15)
- Once initiated, how does toxic tissue injury expand? (2012) (15)
- Temporal changes in tissue repair upon repeated exposure to thioacetamide. (1998) (15)
- Effect of chlorphentermine on the pulmonary disposition of 5-hydroxytryptamine in the isolated perfused rabbit lung. (1980) (15)
- Effect of antimitotic agent colchicine on carbon tetrachloride toxicity (2005) (15)
- Absence of metabolism of morphine during accumulation by isolated perfused rabbit lung. (1979) (15)
- Onset and recovery from chlordecone- and mirex-induced hepatobiliary dysfunction. (1981) (15)
- Biochemical assessment of the genotoxicity of the in vitro interaction between chlordecone and carbon tetrachloride in rat hepatocytes (1991) (14)
- Tissue Repair Response as a Function of Dose during Trichloroethylene Hepatotoxicity (1998) (14)
- Uptake and metabolism of chlorpromazine by rat and rabbit lungs. (1980) (14)
- Possible molecular mechanism of mirex-induced hepatobiliary dysfunction. (1979) (14)
- Absence of diamine oxidase activity from rabbit and rat lungs. (1986) (14)
- Effect of drug-induced phospholipidosis on pulmonary disposition of pneumophilic drugs. (1983) (13)
- Tissue repair response as a function of dose during trichloroethylene hepatotoxicity. (1998) (13)
- Glutathione status in constituted physiological fluids containing albumin. (1987) (13)
- Chemical reactivity-absorption, retention, metabolism, and elimination of hexachlorocyclopentadiene. (1977) (13)
- Metabolism of aldicarb pesticide in laying hens. (1972) (13)
- Ongoing hepatocellular regeneration and resiliency toward galactosamine hepatotoxicity (2005) (13)
- Liver regeneration: a critical toxicodynamic response in predictive toxicology. (2004) (13)
- Injury and repair as opposing forces in risk assessment. (1995) (13)
- The uptake and metabolism of cystamine and taurine by isolated perfused rat and rabbit lungs. (1995) (13)
- Topical exposure to chlordane reduces the contact hypersensitivity response to oxazolone in BALB/c mice. (1995) (13)
- Pesticide-induced modification of hepatobiliary function: hexachlorobenzene, DDT and toxaphene. (1978) (13)
- Differential protooncogene expression in Sprague Dawley and Fischer 344 rats during 1,2-dichlorobenzene-induced hepatocellular regeneration. (1999) (12)
- Adaptive tolerance in mice upon subchronic exposure to chloroform: Increased exhalation and target tissue regeneration. (2006) (12)
- Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy (1988) (12)
- Editorial Medline Coverage (2001) (12)
- Disrupted G1 to S phase clearance via cyclin signaling impairs liver tissue repair in thioacetamide-treated type 1 diabetic rats. (2005) (12)
- Dose-dependent liver tissue repair after chloroform plus trichloroethylene binary mixture. (2005) (12)
- Chlordecone-induced hepatic dysfunction. (1981) (12)
- Lack of effects of chlordecone on synthesis rates, steady state levels and metabolites of catecholamines in rat brain. (1984) (12)
- Evidence for stimulated glutathione synthesis by phenobarbital pretreatment during an oxidative challenge in isolated hepatocytes. (1991) (12)
- Loss of calcium homeostasis leads to progressive phase of chlordecone-potentiated carbon tetrachloride hepatotoxicity. (1993) (11)
- Formation of polar metabolites from aldrin by pea and bean root preparations. (1973) (11)
- Uptake and accumulation of chlorpromazine in the isolated perfused rabbit lung. (1979) (11)
- High Glucose Concentration Alters Cell Proliferation Dynamics in Human Hepatoma Cells (1999) (11)
- Chlordecone-induced fat depletion in the male rat. (1982) (11)
- Potentiation of BrCCl3 hepatotoxicity by chlordecone: biochemical and ultrastructural study. (1991) (10)
- Colchicine antimitosis causes progression of S-(1,2-dichlorovinyl)-L-cysteine-induced injury leading to acute renal failure and death in mice. (2006) (10)
- Comparison of brain discrete area distributions of chlordecone and mirex in the mouse. (1982) (10)
- Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform. (2006) (10)
- Passive sequestration of putrescine, spermidine and spermine by rat lungs. (1988) (10)
- The role of NF-κB signaling in impaired liver tissue repair in thioacetamide-treated type 1 diabetic rats☆ (2005) (10)
- Mechanisms of inhibited liver tissue repair in toxicant challenged type 2 diabetic rats. (2007) (10)
- In vivo and in vitro synthesis, release, and uptake of [3-H]-dopamine in mouse striatal slices after in vivo exposure to chlordecone. (1986) (10)
- Pulmonary metabolism of imipramine in the rat and rabbit. Comparison with hepatic metabolism. (1981) (10)
- Effects of drug-induced pulmonary phospholipidosis on lung mechanics in rats. (1989) (9)
- The incorporation of choline analogues into the phomolipids of phormia regina (1970) (9)
- Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats (2005) (9)
- Microarray analysis of thioacetamide-treated type 1 diabetic rats. (2006) (9)
- The effect of dietary exposure to a mirex plus chlordecone combination on CCl4 hepatotoxicity. (1985) (9)
- Hepatotoxicity and lethality of halomethanes in Mongolian gerbils pretreated with chlordecone, phenobarbital or mirex (2006) (9)
- Calpastatin overexpression prevents progression of S-1,2-dichlorovinyl-l-cysteine (DCVC)-initiated acute renal injury and renal failure (ARF) in diabetes. (2006) (9)
- Uptake and disposition of putrescine, spermidine, and spermine by rabbit lungs. (1987) (8)
- Induction of hepatic mixed function oxidases by photomirex. (1979) (8)
- Aldrin Epoxidase Activity in Developing Rabbit Lung (1980) (8)
- N-oxidation of N,N-dimethylaniline in the rabbit and rat lung. (1983) (8)
- Aldrin epoxidation by plant root extracts (1973) (8)
- Effect of chlorphentermine on the pulmonary clearance of 5-hydroxytryptamine in rabbits in vivo. (1983) (8)
- Phosphatidyl Carnitine: a Possible Intermediate in the Biosynthesis of Phosphatidyl β-Methylcholine in Phormia regina (Meigen) (1966) (8)
- Wnt/β-Catenin Signaling Drives Thioacetamide-Mediated Heteroprotection Against Acetaminophen-Induced Lethal Liver Injury (2017) (7)
- Perturbations in polyamines and related enzymes following chlordecone-potentiated bromotrichloromethane hepatotoxicity. (1990) (7)
- Use of isolated perfused lung in determining pulmonary disposition and potential toxicological significance of inhaled environmental pollutants (1982) (7)
- Possible nephrotoxic effect of carbon tetrabromide and its interaction with chlordecone. (1983) (7)
- S-(1,2-Dichlorovinyl)-l-Cysteine (2005) (7)
- Role of hepatocellular regeneration in chlordecone potentiated hepatotoxicity of carbon tetrachloride (2004) (7)
- Experimental Mathematical Validation of a Novel Concept of Extended 2-Butoxyethanol Autoprotection (1999) (7)
- Prior administration of a low dose of thioacetamide protects type 1 diabetic rats from subsequent administration of lethal dose of thioacetamide. (2006) (7)
- Pulmonary disposition and effects of drugs on pulmonary removal of endogenous substances. (1984) (7)
- Glutathione turnover in perfused rabbit lung. Effect of external glutathione. (1986) (7)
- Effect of chlorphentermine pretreatment on chlorphentermine uptake by isolated perfused rat lung. (1982) (7)
- Assessment of neurotoxicity induced by oral administration of chlordecone (Kepone) in the mouse. (1981) (6)
- Paradoxical toxicity of CCl4 in isolated hepatocytes from chlordecone, phenobarbital and mirex pretreated rats (1991) (6)
- Absence of potentiation of bromoform hepatotoxicity and lethality by chlordecone. (1983) (6)
- Perturbation of calcium homeostasis by CCl4 in rats pretreated with chlordecone and phenobarbital. (1984) (6)
- Hepatoprotective agent (+)-cyanidanol increases the synthetic phase of hepatocellular regeneration. (1991) (6)
- Chlordecone potentiation of CCl4 hepatotoxicity in ovariectomized rats. (1984) (6)
- Effect of chlorphentermine on the pulmonary disposition of norepinephrine in the isolated perfused rabbit lung. (1981) (6)
- Hepatic uptake, disposition, and metabolism of rubratoxin B in isolated perfused rat liver. (1979) (6)
- Amplification of CCl4 toxicity by chlordecone: destruction of rat hepatic microsomal cytochrome P-450 subpopulation. (1991) (6)
- Bromotrichloromethane hepatotoxicity. The role of stimulated hepatocellular regeneration in recovery: biochemical and histopathological studies in control and chlordecone pretreated male rats. (1990) (6)
- Application of Isolated Organ Perfusion Techniques in Toxicology (2007) (6)
- Appendix 1.35: National Institute for Occupational Safety and Health, US* (2005) (6)
- Dose-dependent liver tissue repair in chloroform plus thioacetamide acute hepatotoxicity. (2004) (5)
- Effect of chlorphentermine pretreatment on the distribution of chlorphentermine in isolated perfused rat lungs (1984) (5)
- Stimulated pulmonary cell hyperplasia underlies resistance to alpha-naphthylthiourea. (2000) (5)
- Comparative toxicology of mirex, photomirex and chlordecone after oral administration to the mouse (1983) (5)
- Effect of chlorphentermine pretreatment on 5-hydroxytryptamine disposition in the isolated perfused rat lung12 (1982) (5)
- Chlordecone. (2020) (5)
- Effects of short‐term and long‐term administration of amiodarone on hepatobiliary function in male rats (1989) (5)
- Neurotoxicity in rats following subchronic amiodarone treatment. (1986) (5)
- Hepatic Overexpression of Annexin A1 and A2 in Thioacetamide-Primed Mice Protects Them Against Acetaminophen-Induced Liver Failure and Death (2016) (4)
- Chlorphentermine uptake by rabbit lung slices. (1980) (4)
- Pulmonary synthesis of 5-hydroxytryptamine in isolated perfused rabbit and rat lung preparations. (1986) (4)
- Genetically Modified Foods Get Bad Rap (2004) (4)
- Modification of carbaryl metabolism in rats with monoamine oxidase inhibitors. (1972) (4)
- Phenobarbital-induced cytoprotective mechanisms in menadione metabolism: the role of glutathione reductase and DT-diaphorase. (1990) (4)
- Precursor utilization of 5-hydroxytryptophan for 5-hydroxytryptamine biosynthesis in isolated and perfused rabbit and rat lungs. (1987) (4)
- 789 Expression of calpastatin and annexin I in newly divided hepatocytes: mechanism behind resistance from acute liver failure (2003) (3)
- Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol. (2007) (3)
- The Metabolism, Storage, and Excretion of Highly Chlorinated Compounds by Mammals (1974) (3)
- Effect of adrenalectomy on chlordecone potentiation of carbontetrachloride hepatotoxicity. (1983) (3)
- The rat red blood cell proteome is altered by priming with 2-butoxyethanol. (2008) (3)
- 7.19 – Halogenated Hydrocarbons (2010) (3)
- Biochemical studies on the age-related toxicity of galactosamine in primary rat hepatocyte cultures. (1992) (3)
- Assessment of photomirex toxicity in the mouse. (1980) (3)
- The role of NF-kappaB signaling in impaired liver tissue repair in thioacetamide-treated type 1 diabetic rats. (2005) (3)
- Role of Tissue Repair in Liver Injury (2007) (3)
- American Board of Toxicology (2014) (2)
- outcome of thioacetamide hepatotoxicity (1994) (2)
- Effect of Hg2+ on accumulation and metabolism of chlorpromazine and imipramine in rat lungs. (1984) (2)
- Impact of chemical interactions on the development of cancer (1989) (2)
- 9.29 – Thioacetamide (2010) (2)
- Effect of endrin and endrin derivatives on hepatobiliary function and carbon tetrachloride-induced hepatotoxicity in male and female rats. (1986) (2)
- Pristane-induced effects on cytochrome P-4501A, ornithine decarboxylase and putrescine in rats. (1995) (2)
- In vivo metabolism of CCl sub 4 by gerbils pretreated with chlordecone, phenobarbital, or mirex (1990) (2)
- Correlation between neurotoxicity and chlordecone (Kepone) levels in brain and plasma in the mouse. (1981) (2)
- Uptake and disposition of aldrin and dieldrin by isolated perfused rabbit lung. (1975) (2)
- Halomethane-chlordecone (CD) interactive hepatotoxicity--current concepts on the mechanism. (1993) (2)
- Acceptable Daily Intake (ADI) (2019) (2)
- Hamner Institutes for Health Sciences, The (2014) (2)
- Polyamine Protection Against Chemically Induced Hepatotoxicity (2000) (2)
- Alterations of xenobiotic excretory function induced by potassium dichromate or carbon tetrachloride pretreatment. (1980) (2)
- Drug-specificity in the perturbation of pulmonary disposition of serotonin in rabbit in vivo. (1983) (2)
- Decreased bioactivation and/or detoxification does not explain resiliency of diabetic mice to acetaminophen hepatotoxicity and lethality (2001) (1)
- Bromotrichloromethane Hepatotoxicity. The Role of Stimulated Hepatocellular Regeneration in Recovery: Biochemical and Histopathological Studies in Control and Chlordecone Pretreated Male Rats (1990) (1)
- Oxidative metabolism of aldrin by subcellular root fractions of several plant species. (1972) (1)
- Role of Tissue Repair and Death Proteins in Liver Injury (2013) (1)
- Biochemical Mechanisms of Biphasic Dose-Response Relationships: Role of Hormesis (2017) (1)
- BAL (British Antilewisite) (2005) (1)
- Heat Shock Proteins (2005) (1)
- Effects of cysteine and diethylmaleate pretreatments on renal function and response to a nephrotoxicant (1986) (1)
- Effect of chlorphentermine on incorporation of [14C]choline in the rat lung phospholipids (1986) (1)
- Effects of preexposure to morphine and pentobarbital on disposition of methadone in isolated rat livers. (1978) (1)
- Modification of hepato biliary function by dietary clofibrate (1980) (1)
- Modification of hepatobiliary function by toxic chemicals. (1979) (1)
- Measuring Covalent Binding in Hepatotoxicity (2007) (1)
- Potentiation of mortality by carbon tetrachloride during morphine pellet implantation in the mouse. (1979) (1)
- Diabetes, Effect of Toxicity (2005) (1)
- Hepatocellular Regeneration as a Determinant of Halomethane Hepatotoxicity (1990) (1)
- Hepatic regeneration as a possible mechanism for the hepatoprotective action off (+)-cyanidanol (1990) (1)
- INTERACTION PROFILE FOR : CESIUM , COBALT , STRONTIUM , POLYCHLORINATED BIPHENYLS , and TRICHLOROETHYLENE (2002) (1)
- Alcoholic Beverages and Health Effects (2014) (1)
- Appendix 1.37: National Institutes of Health* (2005) (0)
- Appendix 1.47: Society of Toxicology** (2005) (0)
- Dichloroethylene, 1,2- (2005) (0)
- Comparison of Serum Bilirubin Levels in Humans and Two Monogastric Animal Species After a Single Administration of Sulfisoxazole (1982) (0)
- 861 Tissue repair: a key player in increased carbon tetrachloride-hepatotoxicity in type 2 diabetic rats (2003) (0)
- British Anti-Lewisite (BAL) (2013) (0)
- Nuclear factor PPAR‐α induction in the heart plays a pivotal role in determining the final outcome of doxorubicin‐induced cardiotoxicity (2007) (0)
- Appendix 1.01: Academy of Toxicological Sciences (2005) (0)
- Appendix 1.04: American Board of Toxicology* (2005) (0)
- Nonalcoholic Steatohepatitis (NASH): Mechanism of hepatotoxic sensitivity (2006) (0)
- Appendix 1.06: American College of Toxicology (2005) (0)
- Fetal Alcohol Syndrome (2005) (0)
- Mechanisms of Toxicity (2005) (0)
- Inhibition of cell division in hepatoma cell cultures by chlordecone and carbon tetrachloride combination. (1990) (0)
- Methyl-CCNU (Semustine) (2014) (0)
- Effect of storage on chlorpromazine and imipramine N-oxidizing activity of rat lung microsomes. (1984) (0)
- Mechanisms of inhibited liver tissue regeneration in type 2 diabetes following hepatotoxicant challenge (2006) (0)
- Appendix 1.33: National Center for Environmental Health (2005) (0)
- Editorial (2001) (0)
- Upregulated cardioprotective mechanisms protect diet restricted rats against doxorubicin‐induced cardiotoxicity (2006) (0)
- Comparative evaluation of sequestration of polyamines by perfused rabbit and rat lungs. (1990) (0)
- 6. Toxicodynamic Interactions (2010) (0)
- Liver Regeneration and Tissue Repair (2010) (0)
- Appendix 1.19: Food and Drug Administration, US (2005) (0)
- Difluoroethylene, 1,1- (2005) (0)
- Appendix 1.34: National Center for Toxicological Research (2005) (0)
- Appendix 1.39: National Toxicology Program (2005) (0)
- Alcoholic Beverages and Alcoholism (2005) (0)
- Appendix 1.15: European Society of Toxicology (2005) (0)
- Appendix 1.09: CIIT Centers for Health Research (2005) (0)
- Good Clinical Practice (2013) (0)
- National Center for Environmental Health-ATSDR (2014) (0)
- Good Clinical Practice (GCP) (2005) (0)
- TOXICOLOGICAL HIGHLIGHT PPAR-a: A Key to the Mechanism of Hepatoprotection by Clofibrate (2000) (0)
- Academy of Toxicological Sciences (2014) (0)
- Appendix 1.45: Society for Environmental Toxicology and Chemistry (2005) (0)
- Genetically Modified Foods: Why the Public Frenzy? Role of Mainstream News Media (2004) (0)
- Relationship of hepatotoxicity and lethality with metabolic constants of BrCCl3 in rats pretreated with chlordecone, phenobarbital and mirex☆ (1990) (0)
- Effect of chlorphentermine pretreatment on the distribution of chlorphentermine in isolated perfused rat lungs. (1984) (0)
- Science in India discussed (1984) (0)
- Appendix 1.40: Occupational Safety and Health Administration (2005) (0)
- Microsomal mediated in vitro metabolism of amiodarone (1986) (0)
- 1185 – KEPONE-INDUCED HEPATOBILIARY DYSFUNCTION AND INTERACTION WITH CARBON TETRACHLORIDE (1978) (0)
- Endogenous inhibitors of death proteins inhibit the progression of hemolytic injury (2006) (0)
- Effect of chlorphentermine pretreatment on 5-hydroxytryptamine disposition in the isolated perfused rat lung. (1982) (0)
- Biochemical Methods of Studying Hepatotoxicity (2020) (0)
- N-Nitrosodimethylamine (2019) (0)
- Appendix 1.28: International Society for the Study of Xenobiotics (2005) (0)
- Effect of Chlorphentermine on the Pulmonary Disposition of S-Hydroxytryptamine In the Isolated Perfused (1980) (0)
- The uptake and metabolism of cystamine and taurine by isolated, ventilated and perfused rat and rabbit lungs (1991) (0)
- Appendix 1.36: National Institute of Environmental Health Sciences (2005) (0)
- Society of Toxicology (2014) (0)
- Cytoprotective Mechanisms that Offset the Potential Augmentation of Phenobarbital-Induced O 2 ⨪ Generation During Quinone Recycling (1990) (0)
- 803 Inhibited NF-ϰB transcriptional regulation may explain failed tissue repair in thioacetamide-induced acute liver failure in type I diabetic rats (2003) (0)
- Therapeutic rescue of mice treated with a lethal dose of acetaminophen (2011) (0)
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