Helmut Ponta
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Biology
Helmut Ponta's Degrees
- Bachelors Biology University of Cologne
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(Suggest an Edit or Addition)Helmut Ponta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- CD44: From adhesion molecules to signalling regulators (2003) (2214)
- A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells (1991) (1763)
- Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone (1990) (1542)
- Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression. (1993) (589)
- A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP‐1. (1994) (541)
- CD44 is required for two consecutive steps in HGF/c-Met signaling. (2002) (515)
- Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters (1988) (506)
- The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44. (2001) (441)
- Participation in normal immune responses of a metastasis-inducing splice variant of CD44. (1992) (435)
- Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression. (1994) (430)
- A human homologue of the rat metastasis-associated variant of CD44 is expressed in colorectal carcinomas and adenomatous polyps (1993) (386)
- CD44 variant exon epitopes in primary breast cancer and length of survival (1995) (381)
- CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines. (1991) (357)
- Prevention of tumor metastasis formation by anti-variant CD44 (1993) (356)
- Activated human lymphocytes and aggressive non-Hodgkin's lymphomas express a homologue of the rat metastasis-associated variant of CD44 (1993) (341)
- Splicing choice from ten variant exons establishes CD44 variability. (1993) (301)
- CD44 splice variants: metastases meet lymphocytes. (1993) (278)
- Interference between pathway‐specific transcription factors: glucocorticoids antagonize phorbol ester‐induced AP‐1 activity without altering AP‐1 site occupation in vivo. (1992) (273)
- The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior. (1993) (248)
- The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region. (1987) (247)
- Interdomain binding mediates tumor growth suppression by the NF2 gene product (1997) (231)
- Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. (2007) (220)
- Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa. (1993) (210)
- Hepatocyte growth factor-induced Ras activation requires ERM proteins linked to both CD44v6 and F-actin. (2006) (188)
- An Essential Role for CD44 Variant Isoforms in Epidermal Langerhans Cell and Blood Dendritic Cell Function (1997) (187)
- DNA damage-induced gene expression: signal transduction and relation to growth factor signaling. (1992) (186)
- Coupling of signal transduction to alternative pre‐mRNA splicing by a composite splice regulator (1998) (178)
- A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowth. (1998) (175)
- Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene. (1983) (173)
- CD44 Acts Both as a Growth‐ and Invasiveness‐Promoting Molecule and as a Tumor‐Suppressing Cofactor (2000) (169)
- A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis. (2009) (167)
- Autoregulation of fos: the dyad symmetry element as the major target of repression. (1989) (164)
- A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells. (1993) (160)
- Comparison of immunohistochemistry and RT‐PCR for detection of CD44v‐expression, a new prognostic factor in human breast cancer (1995) (160)
- Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity (1996) (151)
- DNA sequences outside the receptor‐binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones. (1988) (150)
- Molecules in focus The CD44 protein family (1998) (142)
- Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid (2001) (137)
- Surface protein expression and messenger RNA-splicing analysis of CD44 in uterine cervical cancer and normal cervical epithelium. (1994) (132)
- Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties. (1985) (124)
- ULTRAVIOLET‐RADIATION INDUCED c‐jun GENE TRANSCRIPTION: TWO AP‐1 LIKE BINDING SITES MEDIATE THE RESPONSE (1992) (119)
- UV-induced transcription from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat and UV-induced secretion of an extracellular factor that induces HIV-1 transcription in nonirradiated cells (1989) (116)
- The Fos and Jun/AP-1 proteins are involved in the downregulation of Fos transcription. (1989) (115)
- Interference of pathway specific transcription factors. (1992) (115)
- Protein kinase induction in Escherichia coli by bacteriophage T7. (1974) (105)
- Variant Exons v6 and v7 Together Expand the Repertoire of Glycosaminoglycans Bound by CD44* (1997) (105)
- Hyaluronate-independent metastatic behavior of CD44 variant-expressing pancreatic carcinoma cells. (1996) (100)
- In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase. (1975) (94)
- Perspectives of CD44 targeting therapies (2014) (93)
- Identification of IHABP, a 95 kDa intracellular hyaluronate binding protein. (1998) (92)
- CD44 expression and regulation during mammary gland development and function. (2000) (92)
- The CD44 protein family. (1998) (87)
- CD44 in colon cancer. (1995) (78)
- The CD44 proteins in embryonic development and in cancer. (1996) (78)
- Hyaluronate-enhanced hematopoiesis: two different receptors trigger the release of interleukin-1beta and interleukin-6 from bone marrow macrophages. (1999) (75)
- 'Nuclear' oncogenes convert extracellular stimuli into changes in the genetic program. (1989) (75)
- A five-amino-acid peptide blocks Met- and Ron-dependent cell migration. (2005) (75)
- Adhesion proteins meet receptors: a common theme? (2008) (72)
- Retardation of metastatic tumor growth after immunization with metastasis‐specific monoclonal antibodies (1990) (70)
- Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling. (2016) (69)
- Prognostic value of CD44 variant expression in primary breast cancer (1999) (64)
- Trans‐acting factors regulate the expression of CD44 splice variants. (1996) (60)
- Growth retardation of tumors by adoptive transfer of cytotoxic T lymphocytes reprogrammed by CD44V6‐specific SCFV: ζ‐chimera (1996) (60)
- Transcription initiation of transfected mouse mammary tumor virus LTR DNA is regulated by glucocorticoid hormones. (1983) (59)
- Haploinsufficiency of c-Met in cd44−/− Mice Identifies a Collaboration of CD44 and c-Met In Vivo (2007) (58)
- Two different functions for CD44 proteins in human myelopoiesis. (1998) (58)
- Purification and properties of DNA-dependent RNA polymerases from yeast. (1972) (56)
- The Activation and Activity Control of AP‐1 (Fos/Jun) (1993) (56)
- The long terminal repeat region of the mouse mammary tumour virus contains multiple regulatory elements. (1990) (54)
- Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene: synergism of steroid hormone action (1988) (53)
- Mutual cross-modulation of steroid/retinoic acid receptor and AP-1 transcription factor activities A novel property with practical implications (1994) (53)
- Tumor metastasis formation: cell-surface proteins confer metastasis-promoting or -suppressing properties. (1994) (53)
- Radiation-induced activation of transcription factors in mammalian cells (1990) (51)
- c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice (2011) (50)
- CD44 variant-specific antibodies trigger hemopoiesis by selective release of cytokines from bone marrow macrophages. (2002) (48)
- How tumor cells make use of CD44. (1998) (48)
- Production of mouse mammary tumor virus upon transfection of a recombinant proviral DNA into cultured cells. (1985) (48)
- Chapter 4 Adhesion Proteins Meet Receptors (2008) (47)
- CD44 isoforms in metastatic cancer. (1994) (41)
- DNA‐dependent RNA polymerases from yeast. Partial characterization of three nuclear enzyme activities (1971) (41)
- Accelerated immune response in transgenic mice expressing rat CD44v4-v7 on T cells. (1996) (41)
- Helper function of T7 protein kinase in virus propagation (1975) (41)
- Problems with RHAMM A New Link between Surface Adhesion and Oncogenesis? (1998) (39)
- The role of CD44 splice variants in human metastatic cancer. (1995) (39)
- Mechanisms of the ultraviolet light response in mammalian cells. (1989) (39)
- Characterisation of the murine gene encoding the intracellular hyaluronan receptor IHABP (RHAMM). (1999) (39)
- An Update of the Mammalian UV Response: Gene Regulation and Induction of a Protective Function (1989) (36)
- Protein kinase of bacteriophage T7. 2. Properties, enzyme synthesis in vitro and regulation of enzyme synthesis and activity in vivo. (1975) (36)
- Expression of variant CD44 epitopes in human astrocytic brain tumors (1995) (35)
- Regulation of gene expression by steroid hormones. (1992) (35)
- DNA sequences involved in the regulation of gene expression by glucocorticoid hormones. (1984) (34)
- Positive and negative regulation of collagenase gene expression. (1992) (33)
- CD44 variant isoforms are essential for the function of epidermal Langerhans cells and dendritic cells. (1998) (32)
- Expression of CD44 isoforms in human skin cancer. (1996) (32)
- 12-O-tetradecanoylphorbol 13-acetate-inducible proteins are synthesized at an increased rate in Bloom syndrome fibroblasts. (1982) (32)
- Human mammary carcinomas express homologues of rat metastasis-associated variants of CD44 (2004) (32)
- Development of Escherichia coli virus T1. The role of the proton-motive force. (1980) (31)
- Cd44 and Splice Variants of Cd44 in Normal Differentiation and Tumor Progression (1993) (30)
- Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress (2016) (29)
- Increasing incidence of CD44v7/8 epitope expression during uterine cervical carcinogenesis (1996) (28)
- Protein kinase of bacteriophage T7. 1. Purification. (1975) (27)
- CD44 splice variants; expression on lymphocytes and in neoplasia. (1993) (26)
- CD44 expression is aberrant in benign Schwann cell tumors possessing mutations in the neurofibromatosis type 2, but not type 1, gene. (1997) (26)
- A B-lymphocyte-specific high-turnover protein: Constitutive expression in resting B cells and induction of synthesis in proliferating cells (1982) (26)
- Activation-dependent modulation of hyaluronate-receptor expression and of hyaluronate-avidity by human monocytes. (1998) (25)
- Steroids and growth promoting factors in the regulation of expression of genes and gene networks (1992) (24)
- Involvement of fos in spontaneous and ultraviolet light‐induced genetic changes (1991) (23)
- Different regions of the estrogen receptor are required for synergistic action with the glucocorticoid and progesterone receptors (1989) (22)
- Nuclear oncoproteins determine the genetic program in response to external stimuli. (1988) (22)
- Inhibition of MT-450 rat mammary tumour growth by antibodies recognising subtypes of blood group antigen B (1999) (22)
- The endogenous mouse mammary tumour virus locus Mtv-8 contains a defective envelope gene. (1986) (22)
- Mouse mammary tumour virus: a proviral gene contributes to the understanding of eukaryotic gene expression and mammary tumorigenesis. (1985) (20)
- The CD44 protein family: roles in embryogenesis and tumor progression. (1998) (20)
- The proviral DNA of mouse mammary tumor virus: Its use in the study of the molecular details of steroid hormone action (1983) (20)
- CD44 splice variants: expression during lymphocyte activation and tumor progression. (1993) (19)
- Recent advances in the genetics of metastasis. (1994) (19)
- The sex-factor-dependent exclusion of coli virus T7. (1975) (18)
- CD44 variant exon v5 encodes a tyrosine that is sulphated. (1998) (17)
- Delimitation of a DNA sequence which confers inducibility by glucocorticoid hormones (1982) (16)
- Transcriptional units for ribosomal proteins of Escherichia coli. (1975) (16)
- Productive T7 infection of Escherichia coli F+ cells and anucleate minicells (1977) (16)
- The regulation of expression of mouse mammary tumor virus DNA by steroid hormones and growth factors. (1989) (16)
- Differentiated cells from BALB/c mice differ in their radiosensitivity. (1981) (16)
- A Splice Variant of CD44 Expressed in the Rat Apical Ectodermal Ridge Contributes to Limb Outgrowth (1996) (15)
- [The mechanisms of uptake of zinc by baker's yeast]. (1970) (14)
- Schwann cell tumors express characteristic patterns of CD44 splice variants (1995) (14)
- The endogenous proviral mouse mammary tumor virus genes of the GR mouse are not identical and only one corresponds to the exogenous virus. (1981) (13)
- Efficient lysis of CD44v7/8-presenting target cells by genetically engineered cytotoxic T-lymphocytes--a model for immunogene therapy of cervical cancer. (1997) (13)
- in Colon Cancer (1995) (12)
- Membrane alteration induced by T7 virus infection (1977) (12)
- A deletion mutant of mouse mammary tumour virus, lacking 516 nucleotides of the 5' long terminal repeat sequence, can be expressed in a hormone-responsive fashion. (1983) (11)
- Control of gene expression in bacteriophage T7: Transcriptional controls (2004) (10)
- Transforming growth factor-beta represses transcription of the mouse mammary tumour virus DNA in cultured mouse mammary cells. (1990) (10)
- Analysis of molecular functions of the tumor metastasis promoting surface molecule CD44v4-v7 using transgenic mice. (1994) (10)
- Hormonal regulation of cell surface expression of the major histocompatibility antigen H‐2Ld in transfected cells. (1985) (10)
- Genes upregulated in a metastasizing human colon carcinoma cell line (2005) (9)
- BIOCHEMISTRY OF DEVELOPMENT OF E.COLI VIRUSES T7 AND T1 (1978) (8)
- Early T7 gene expression: rates of RNA synthesis and degradation, protein kinase dependent termination of transcription, and efficiency of translation. (1978) (8)
- Antagonistic Signaling Pathways Regulate Alternative Splicing of CD44 in T Cells (2002) (7)
- Development of Escherichia coli virus T1: repression of host gene expression. (1977) (7)
- A virus-specified mechanism for the prevention of multiple infection—T7- and T3-mutual and superinfection exclusion (1976) (7)
- Transcription factors in normal and malignant cells (1990) (6)
- Transcription of yeast DNA in vitro. Preparation of yeast DNA which is used as template by the purified DNA-dependent RNA polymerases A and B from yeast. (1974) (6)
- Early T7 gene expression (1978) (6)
- Development ofE. coli virus T1: The pattern of gene expression (1977) (6)
- The Role of FOS in Gene Regulation (1990) (5)
- E. coli membranes become permeable to ions following T7-virus-infection (1976) (5)
- Expression of proviral DNA of mouse mammary tumour virus and its transcriptional control sequences. (1984) (5)
- Radiation and mutagen inducible mammalian genes. (1982) (5)
- Chapter 5 DNA-Dependent RNA Polymerases from Yeasts (1975) (5)
- A Major Decision: Proliferation or Differentiation. Interactions Between Pathwayspecific Transcription Factors Exemplify a Molecular Mechanism for the Decision (1990) (4)
- Radiation sensitivity of messenger RNA (1979) (4)
- Glucocorticoid hormone interactions with cloned proviral DNA of mouse mammary tumor virus. (1984) (4)
- Genetic changes in mammalian cells reminiscent of an SOS response (2004) (4)
- Control of gene expression in bacteriophage T7 (2004) (4)
- Protein kinase of Acetabularia. (1975) (3)
- THE CD 44 PROTEIN FAMILY : ROLES IN EMBRYOGENESIS AND TUMOR PROGRESSION (2007) (3)
- Metastatic Tumor Cells Mimic Lymphocytes (1992) (3)
- Two Nuclear Oncogene Products Cooperate in the Formation of the Transcription Factor Ap-1 (1989) (2)
- Relevance of CD44 Variant Epitopes for Diagnosis and Therapy of Human Breast Cancer (1995) (2)
- CD44 splice variants in draining lymph nodes precede allograft rejection of endocrine cells (1999) (1)
- Hormonal Control of Mouse Mammary Tumor Virus Transcription (1987) (1)
- RNA Polymerase Modifications after T-Phage Infections of E. coli (1976) (1)
- Peptides Derived from Exon v6 of the CD44 Extracellular Domain Prevent Activation of Receptor Tyrosine Kinase and Subsequently Angiogenesis and Metastatic Spread of Tumor Cells (2009) (1)
- PROTEIN "X" SYNTHESIS IN MAMMALIAN CELLS (1981) (1)
- Proceedings: Transcriptional units for ribosomal proteins. (1974) (1)
- CD44 isoforms in prognosis of breast cancer (1995) (1)
- The privilege of expressing CD44v - used by immune cells, misused by tumour cells (1996) (1)
- Hormonal response region in the in terminal repeat can be dissociated has enhancer properties (glucocorticoid hormone induction/mouse mammary tumor virus/lot (2016) (0)
- Perspectives of CD44 targeting therapies (2014) (0)
- CD44 splice variants in tumor metastasis (1993) (0)
- Efficient Treatment of Metastatic Pancreatic Cancer via Targeted Inhibition of CD44v6 Signaling (2016) (0)
- A 50-bp DNA segment preceding the MMTV LTR RNA initiation site is sufficient to cause glucocorticoid-sensitive transcription of a LTR-tk chimeric gene (1983) (0)
- DNA-dependent RNA polymerases from yeasts. (1975) (0)
- Molecular functions of the tumor progession protein CD44 (1997) (0)
- A method for diagnosis and analysis of adenocarcinomas (1993) (0)
- Phorbol Ester Tumor Promoters and the Anti-Tumor-Promoter Dexamethasone Share a Molecular Target: Modulation of the Transcription Factor Ap-1 by a Novel Type of Interaction (1991) (0)
- Signals governing mouse mammary tumor virus expression in vivo and in cultured cells upon proviral DNA transfer. (1982) (0)
- Different Regions oftheEstrogen Receptor AreRequired for Synergistic Action withtheGlucocorticoid and Progesterone Receptors (1989) (0)
- The Role of Variant Forms of CD44 in Adhesion and Metastasis (1992) (0)
- Variant CD44 oberflaechenproteine, this coding c-DNA sequences, antibodies against these proteins and their use in the diagnosis and therapy (1990) (0)
- The co-receptor function of CD44v6 towards c-Met in vitro and in vivo (2004) (0)
- A Dominant Metastogene Confers Metastatic Potential to Tumor Cells (1993) (0)
- Biennial report 1979/80 (1981) (0)
- Gene expression in mitochondria and bacteria (1977) (0)
- containing use of antibody preparations for immunosuppression (1991) (0)
- Variant CD44 surface proteins, these coding dna sequences, antibody therapy against these proteins and their use in the diagnosis and. (1991) (0)
- peptidic compounds and their derivatives for the treatment of human disease by inhibiting the signaling pathway by growth factors. (2004) (0)
- Oligonucleotide substituted mutagenesis of the hormone response element of MMTV identify regions necessary for glucocorticoid, progestin and androgen induction of transcription (1987) (0)
- Prevention o f Tumor Metastasis Formation by Anti-Variant CD 44 By (2003) (0)
- Peptidic compounds and their derivatives for the Behandllung of human diseases by inhibition of signal transmission via growth factors (2004) (0)
- Control of Gene Expression by E. coli Virus T7 (1974) (0)
- Mode of action of hyaluronate enhancement of hemopoiesis (1999) (0)
- Using anti-CD44 antibodies containing preparations for the treatment of certain tumors and for the suppression of immune responses (1997) (0)
- Late abstracts 186–187 (2005) (0)
- The privilege of expressing CD44v cells, misused by tumour cells. (1996) (0)
- Means for identifying and treatment of metastatic tumors (1996) (0)
- By exon v5 of the CD44 gene encoded polypeptides as targets for immunotherapy and immunoscintigraphy of tumors (1993) (0)
- Protein kinase ofAcetabularia (2005) (0)
- Function of the first dominant metastogene: A new surface glycoprotein controls a metastasis-specific genetic program (1991) (0)
- Transcriptional control sequences in the long terminal repeat of mouse mammary tumor virus have hormone induction and enhancer qualities (1984) (0)
- A new method to detect metastasis-associated CD44-splice variants (CD44v) in paraffin-embedded specimen of human skin cancer (1994) (0)
- CD44v6 peptides block metastasis and interfere with angiogenesis (2008) (0)
- The variant CD44 surface proteins, DNA sequences coding therefor, antibodies to these proteins and their use in diagnostics and therapy (1991) (0)
- CD44 in Normal Differentation and Tumor Progression (1993) (0)
- CD44 splice variants: metastases lyrnphocytes (1993) (0)
- Third symposium onAcetabularia (1975) (0)
- VIRUS T7: A PROBE OF CELLULAR CONTROL MECHANISMS (1979) (0)
- Methods to prepare mutated CD44 surface proteins and these proteins are active against the antibodies (1997) (0)
- Varianta CD44 ytproteiner, a DNA sequencer which encodes Foer dem, antikroppar towards these proteiner samt deras anvaendning i Diagnos Science terapi (1992) (0)
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What Schools Are Affiliated With Helmut Ponta?
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