H. robson Macdonald

H. robson Macdonald's AcademicInfluence.com Rankings

H. robson Macdonald

Biology

#4482

World Rank

#6678

Historical Rank

Immunology

#193

World Rank

#202

Historical Rank

biology Degrees

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Biology

H. robson Macdonald's Degrees

PhD Immunology Stanford University
Doctorate Medicine University of California, San Francisco

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H. robson Macdonald's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Deficient T cell fate specification in mice with an induced inactivation of Notch1. (1999) (1523)
NKT cells: what's in a name? (2004) (1201)
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (2009) (1065)
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (2008) (996)
T-cell receptor Vβ use predicts reactivity and tolerance to Mlsa- encoded antigens (1988) (899)
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. (1988) (838)
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. (2004) (805)
Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells (1985) (628)
Notch regulation of lymphocyte development and function (2004) (597)
An HMG-box-containing T-cell factor required for thymocyte differentiation (1995) (568)
Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. (1987) (557)
Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). (1993) (532)
Notch signaling in the immune system. (2010) (499)
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : I. RESPONSE OF NORMAL AND IMMUNE MOUSE SPLEEN CELLS IN MIXED LEUKOCYTE CULTURES (1974) (475)
Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus (2001) (448)
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment (2008) (446)
β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis (2004) (391)
Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium tuberculosis. (1998) (388)
Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells (2000) (369)
Tissue-specific segregation of CD1d-dependent and CD1d-independent NK T cells. (1999) (369)
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. (2002) (363)
A urine inhibitor of interleukin 1 activity that blocks ligand binding. (1987) (361)
Regulation of innate and adaptive immunity by Notch (2013) (355)
NK1.1+ T cell receptor-alpha/beta+ cells: new clues to their origin, specificity, and function (1995) (353)
Clonal expansion precedes anergy and death of Vβ8+ peripheral T cells responding to staphylococcal enterotoxin B in vivo (1991) (347)
Activated B cells express receptors for, and proliferate in response to, pure interleukin 2 (1984) (340)
Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice (1994) (333)
IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice (1997) (321)
Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. (2005) (299)
TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95). (1997) (296)
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity. (2008) (279)
Two waves of recombinase gene expression in developing thymocytes (1994) (278)
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development (2001) (270)
Growth of mouse megakaryocyte colonies in vitro. (1975) (265)
Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice (1998) (256)
Clonal deletion of V β814-bearing T cells in mice transgenic for mammary tumour virus (1991) (255)
Dormant and Self‐Renewing Hematopoietic Stem Cells and Their Niches (2007) (251)
Programmed death of autoreactive thymocytes (1990) (236)
Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes (1987) (235)
Quantitative Impact of Thymic Clonal Deletion on the T Cell Repertoire (1997) (232)
In Vivo Expression of Natural Killer Cell Inhibitory Receptors by Human Melanoma–Specific Cytolytic T Lymphocytes (1999) (231)
Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency, and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1.5 (1983) (226)
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. (2001) (226)
Extracellular Cyclophilins Contribute to the Regulation of Inflammatory Responses1 (2005) (224)
Granzyme A is an interleukin 1 beta-converting enzyme (1995) (223)
Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors (1980) (219)
Activated B cells express functional Fas ligand (1996) (219)
Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors (1982) (217)
High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61. (1985) (208)
Superantigens of mouse mammary tumor virus. (1995) (206)
Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. (1999) (202)
Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission (1993) (200)
In susceptible mice, Leishmania major induce very rapid interleukin‐4 production by CD4+ T cells which are NK1.1− (1995) (192)
Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes (1985) (191)
Simultaneous loss of β- and γ-catenin does not perturb hematopoiesis or lymphopoiesis (2008) (190)
Hierarchy of Notch–Delta interactions promoting T cell lineage commitment and maturation (2007) (189)
Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides (2002) (187)
Thymic Selection Generates a Large T Cell Pool Recognizing a Self-Peptide in Humans (2002) (180)
Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment (1988) (180)
The Early IL-4 Response to Leishmania major and the Resulting Th2 Cell Maturation Steering Progressive Disease in BALB/c Mice Are Subject to the Control of Regulatory CD4+CD25+ T Cells1 (2002) (178)
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia (2010) (178)
Positive selection of CD4+ thymocytes controlled by MHC class II gene products (1988) (177)
Generation of cytotoxic T lymphocytes in vitro. II. Effect of repeated exposure to alloantigens on the cytotoxic activity of long-term mixed leukocyte cultures. (1974) (167)
In vivo administration of a lentiviral vaccine targets DCs and induces efficient CD8(+) T cell responses. (2003) (165)
Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor (1986) (162)
Deletion of self-reactive T cells before entry into the thymus medulla (1988) (162)
Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand (1996) (156)
A cd3− subset of cd4−8+ thymocytes: a rapidly cycling intermediate in the generation of cd4+8+ cells (1988) (153)
Selective Bystander Proliferation of Memory CD4+ and CD8+ T Cells Upon NK T or T Cell Activation (2000) (151)
Vacuolar H+-Translocating Pyrophosphatase Is Induced by Anoxia or Chilling in Seedlings of Rice (1995) (150)
Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (147)
Neurogenic Subventricular Zone Stem/Progenitor Cells Are Notch1-Dependent in Their Active But Not Quiescent State (2012) (145)
Superantigen-reactive CD4+ T cells are required to stimulate B cells after infection with mouse mammary tumor virus (1993) (143)
Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo (1995) (141)
CD28‐negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients (1999) (140)
Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. (1985) (139)
An exogenous mouse mammary tumor virus with properties of Mls-1a (Mtv- 7) (1992) (139)
Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. (1990) (138)
Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis. (2008) (138)
Cytolytic T lymphocytes. (1983) (135)
Cell specificity of granzyme gene expression. (1990) (133)
Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. (2010) (130)
Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses (2014) (126)
Development and selection of NKT cells. (2002) (125)
Notch signaling in T- and B-cell development. (2004) (125)
The glioblastoma‐derived t cell suppressor factor/ transforming growth factor‐β2 inhibits t cell growth without affecting the interaction of interleukin 2 with its receptor (1988) (123)
Selectively increased production of interferon-gamma by subsets of Lyt-2+ and L3T4+ T cells identified by expression of Pgp-1. (1987) (121)
NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells (2012) (121)
Different staphylococcal enterotoxins bind preferentially to distinct major histocompatibility complex class ii isotypes (1989) (121)
Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. (1998) (120)
Cutting edge: apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo. (1999) (119)
Interleukin 1-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymoma cells. (1986) (118)
Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes (2015) (117)
H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity (1992) (116)
IL-4 rapidly produced by V beta 4 V alpha 8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. (1997) (114)
Heterogeneity of in vitro colony‐ and cluster‐forming cells in the mouse marrow: Segregation by velocity sedimentation (1975) (112)
The Cellular Basis of T-Cell Memory (1989) (108)
Phenotypic and functional properties of murine thymocytes. I. Precursors of cytolytic T lymphocytes and interleukin 2-producing cells are all contained within a subpopulation of “mature” thymocytes as analyzed by monoclonal antibodies and flow microfluorometry (1982) (108)
Intrathymic elimination of Mlsa-reactive (V beta 6+) cells during neonatal tolerance induction to Mlsa-encoded antigens (1988) (108)
Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion (2011) (106)
Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity (1989) (104)
Naturally Acquired MAGE-A10- and SSX-2-Specific CD8+ T Cell Responses in Patients with Hepatocellular Carcinoma1 (2005) (102)
Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes (2013) (102)
Inhibition of T cell-mediated cytolysis by monoclonal antibodies directed against Lyt-2: heterogeneity of inhibition at the clonal level. (1981) (102)
T Cell Receptor δ Gene Rearrangement and T Early α (TEA) Expression in Immature αβ LineageThymocytes: Implications for αβ/γδ Lineage Commitment (1996) (99)
Phenotypic Identification of Memory Cytolytic T Lymphocytes in a Subset of Lyt‐2+ Cells (1987) (98)
Age-associated increase in expression of the T cell surface markers Thy-1, Lyt-1, and Lyt-2 in congenitally athymic (nu/nu) mice: analysis by flow microfluorometry. (1981) (98)
Enrichment of Human CD4+ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors 1 (2009) (97)
A role for gamma delta + T cells during experimental infection of mice with Leishmania major. (1993) (96)
Production and characterization of monoclonal anti‐Thy‐1 antibodies that stimulate lymphokine production by cytolytic T cell clones (1985) (94)
Abnormal distribution of T cell subsets in athymic mice. (1986) (92)
Separation of tumor-infiltrating lymphocytes from tumor cells in human solid tumors. A comparison between velocity sedimentation and discontinuous density gradients. (1986) (91)
T-cell activation. (1986) (91)
Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor. (1988) (89)
Efficient transduction of dendritic cells and induction of a T-cell response by third-generation lentivectors. (2002) (87)
Mutant EL-4 thymoma cells polyclonally activate murine and human B cells via direct cell interaction. (1985) (85)
Functional analysis of T cell subsets from mice bearing the lpr gene. (1985) (85)
Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver (1996) (84)
Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development 1 (2009) (84)
Exogenous and Endogenous Mouse Mammary Tumor Virus Superantigens (1993) (83)
Cutting Edge: Influence of the TCR Vβ Domain on the Avidity of CD1d:α-Galactosylceramide Binding by Invariant Vα14 NKT Cells1 (2003) (83)
Synchronization of mouse L-cells by a velocity sedimentation technique. (1970) (83)
Notch1 and T-cell development: insights from conditional knockout mice. (2001) (82)
Precursors of functional MHC class I- or class II-restricted CD8alphaalpha(+) T cells are positively selected in the thymus by agonist self-peptides. (2002) (82)
Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major (2012) (82)
Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets. (1987) (82)
Regulation of Ig Class Secretion by Soluble Products of Certain T‐Cell Lines (1984) (81)
Oligoclonal expansion of major histocompatibility complex class I- restricted cytolytic T lymphocytes during a primary immune response in vivo: direct monitoring by flow cytometry and polymerase chain reaction (1993) (81)
Cutting Edge: Influence of the TCR Vβ Domain on the Selection of Semi-Invariant NKT Cells by Endogenous Ligands1 (2006) (80)
Allograft immunity in the mouse. II. Physical studies of the development of cytotoxic effector cells from their immediate progenitors. (1973) (80)
Expression of the CD28 costimulatory molecule on subsets of murine intestinal intraepithelial lymphocytes correlates with lineage and responsiveness (1993) (80)
Antibody‐Dependent Cell‐Mediated Cytotoxicity: Heterogeneity of Effector Cells in Human Peripheral Blood (1975) (80)
Expression of genes encoding the pre-TCR and CD3 complex during thymus development. (1995) (79)
Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus (1993) (79)
Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response. (1995) (77)
The cellular basis of T-cell memory. (1989) (77)
Dynamic Regulation of Notch 1 and Notch 2 Surface Expression during T Cell Development and Activation Revealed by Novel Monoclonal Antibodies1 (2009) (77)
The role of Notch signaling during hematopoietic lineage commitment (2002) (76)
Activation of MHC class I-restricted CD8+ CTL by microbial T cell mitogens. Dependence upon MHC class II expression of the target cells and V beta usage of the responder T cells. (1990) (76)
Clonal heterogeneity in the functional requirement for Lyt-2/3 molecules on cytolytic T lymphocytes: analysis by antibody blocking and selective trypsinization (1982) (75)
Dissociation of thymic positive and negative selection in transgenic mice expressing major histocompatibility complex class I molecules exclusively on thymic cortical epithelial cells. (2001) (75)
Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice. (2008) (74)
Cutting Edge: Thymic Crosstalk Regulates Delta-Like 4 Expression on Cortical Epithelial Cells1 (2008) (74)
Peripheral T‐Cell Reactivity to Bacterial Superantigens in vivo: The Response/Anergy Paradox (1993) (74)
Clonal deletion of self-reactive T cells in irradiation bone marrow chimeras and neonatally tolerant mice. Evidence for intercellular transfer of Mlsa (1989) (72)
NLRC5 Exclusively Transactivates MHC Class I and Related Genes through a Distinctive SXY Module (2015) (71)
Targeted Expression of Human CD1d in Transgenic Mice Reveals Independent Roles for Thymocytes and Thymic APCs in Positive and Negative Selection of Vα14i NKT Cells1 (2005) (71)
Superantigens and retroviral infection: insights from mouse mammary tumor virus. (1994) (71)
T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire (1987) (70)
Reduced development of CD4−8−B220+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules (1995) (70)
Clonal analysis of cytolytic T lymphocyte-mediated lysis of target cells with inducible antigen expression: correlation between antigen density and requirement for Lyt-2/3 function. (1985) (70)
A Role for CD147 in Thymic Development (2002) (68)
Precursor frequency analysis of lymphokine-secreting alloreactive T lymphocytes. Dissociation of subsets producing interleukin 2, macrophage-activating factor, and granulocyte-macrophage colony- stimulating factor on the basis of Lyt-2 phenotype (1982) (68)
T cell lineages in the thymus of lpr/lpr mice. Evidence for parallel pathways of normal and abnormal T cell development. (1987) (68)
Pgp-1 (Ly 24) as a marker of murine memory T lymphocytes. (1990) (68)
TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host. (1998) (66)
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO (1974) (66)
Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus (1989) (66)
Quantitation and clonal isolation of cytolytic T lymphocyte precursors selectively infiltrating murine sarcoma virus-induced tumors (1981) (65)
Flow microfluorometric analysis of mouse thymus development in vivo and in vitro (1983) (65)
Notch Signaling Regulates Follicular Helper T Cell Differentiation (2013) (65)
Secretion of IgG1 induction factor by T cell clones and hybridomas (1985) (63)
Unexpectedly late expression of intracellular CD3ϵ and TCR γδ proteins during adult thymus development (1999) (63)
Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4- subset in lpr mice. (1985) (63)
T‐Cell Reactivity and Tolerance to Mlsa‐Encoded Antigens (1989) (63)
αβ Lineage‐committed thymocytes can be rescued by the γδ T cell receptor (TCR) in the absence of TCR β chain (1997) (62)
Mouse CD11c(+) B220(+) Gr1(+) plasmacytoid dendritic cells develop independently of the T-cell lineage. (2002) (62)
T‐Cell Lineages, Repertoire Selection and Tolerance Induction (1988) (62)
Generation of cytotoxic T lymphocytes in vitro. IV. Functional activation of memory cells in the absence of DNA synthesis (1975) (61)
Clonal analysis of cytolytic T lymphocyte specificity. I. Phenotypically distinct sets of clones as the cellular basis of cross- reactivity to alloantigens (1980) (60)
Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. (2001) (60)
Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis (1977) (59)
T cell fate specification and alphabeta/gammadelta lineage commitment. (2001) (59)
Double‐negative thymocyte subsets in CD3′ chain‐deficient mice: Absence of HSA+CD44−CD25− cells (1994) (58)
c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis. (2006) (57)
Antigenic specificity of the cytolytic T lymphocyte (CTL) response to murine sarcoma virus-induced tumors. II. Analysis of the clonal progeny of CTL precursors stimulated in vitro with syngeneic tumor cells. (1980) (56)
Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike1 (2007) (55)
Functional status of interleukin 2 receptors expressed by immature (Lyt-2-/L3T4-) thymocytes. (1986) (55)
A recombinant C-terminal fragment of staphylococcal enterotoxin A binds to human MHC class II products but does not activate T cells. (1991) (54)
Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-Mls-1a controlled by hemopoietic cells in the thymus (1990) (54)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. II. Effect of cortisone and cyclophosphamide on cytolytic T lymphocyte precursor frequencies in the thymus. (1979) (54)
Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex. (1989) (54)
Abnormal expression of T cell receptor genes in Lyt-2- L3T4- lymphocytes of lpr mice: comparison with normal immature thymocytes. (1987) (53)
Differentiation in vitro of Lyt 2+ thymocytes from embryonic Lyt 2− precursors (1983) (53)
Heterogeneity of immature (Lyt-2-/L3T4-) thymocytes. Identification of four major phenotypically distinct subsets differing in cell cycle status and in vitro activation requirements. (1988) (53)
Fas ligand expression is restricted to nonlymphoid thymic components in situ. (1997) (53)
Antigenic specificity of the cytolytic T lymphocyte response to murine sarcoma virus-induced tumors. III. Characterization of cytolytic T lymphocyte clones specific for Moloney leukemia virus-associated cell surface antigens (1980) (53)
Multicellular spheroids: a new model target for in vitro studies of immunity to solid tumor allografts. (1977) (52)
Cutting Edge: An Essential Role for Notch-1 in the Development of Both Thymus-Independent and -Dependent T Cells in the Gut1 (2000) (52)
Antigenic stimulation regulates the expression of IL 2 receptors in a cytolytic T lymphocyte clone. (1985) (51)
Biased Vβ Usage in Immature Thymocytes Is Independent of DJβ Proximity and pTα Pairing1 (2001) (51)
Ligand-dependent Inhibition of CD1d-restricted NKT Cell Development in Mice Transgenic for the Activating Receptor Ly49D (2003) (51)
Absolute requirement for the pre‐T cell receptor α chain during NK1.1+ TCRα β cell development (1999) (50)
Propidium iodide staining correlates with the extent of DNA degradation in isolated nuclei. (1992) (50)
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO III. Velocity Sedimentation Studies of the Differentiation and Fate of Effector Cells in Long-Term Mixed Leukocyte Cultures (1974) (50)
Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: implications for superantigen function (1994) (50)
Staphylococcal enterotoxin-dependent lysis of MHC class II negative target cells by cytolytic T lymphocytes. (1991) (50)
Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors. (1997) (50)
Tissue‐specific segregation of TCRγ δ+ NKT cells according to phenotype TCR repertoire and activation status: parallels with TCR α β+NKT cells (2001) (49)
Transforming growth factors beta slow down cell‐cycle progression in a murine interleukin‐2 dependent T‐cell line (1989) (49)
Notch signaling in hematopoiesis and lymphopoiesis: Lessons from Drosophila (2005) (49)
LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance. (2013) (48)
Developing HSCs become Notch independent by the end of maturation in the AGM region. (2016) (48)
Differential effects of superantigen‐induced “anergy” on priming and effector stages of a T cell‐dependent antibody response (1994) (47)
Point mutations of human interleukin‐1 with decreased receptor binding affinity (1986) (47)
T cell receptor α gene rearrangement and transcription in adult thymic γδ cells (1997) (47)
Gene transfer of the ly‐3 chain gene of the mouse cd8 molecular complex: co‐transfer with the ly‐2 polypeptide gene results in detectable cell surface expression of the ly‐3 antigenic determinants (1988) (47)
Expression of B220 on activated T cell blasts precedes apoptosis. (1997) (46)
Development of cytolytic T lymphocyte precursors in organ-cultured mouse embryonic thymus rudiments (1982) (46)
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair (vol 135, pg 1118, 2008) (2009) (44)
Natural killer‐like T cells develop in SJL mice despite genetically distinct defects in NK1.1 expression and in inducible interleukin‐4 production (1997) (43)
MHC-II-Independent CD4+ T Cells Induce Colitis in Immunodeficient RAG−/− Hosts1 (2001) (43)
Cell cycle regulation of cloned cytolytic T cells by T cell growth factor: analysis by flow microfluorometry. (1982) (42)
Cytolytic T lymphocyte precursor cells in congenitally athymic C57BL/6 nu/nu mice: quantitation, enrichment, and specificity. (1981) (42)
Stimulator cell requirements for allospecific T cell subsets: specialized accessory cells are required to activate helper but not cytolytic T lymphocyte precursors. (1983) (41)
A novel T cell-activating molecule (THAM) highly expressed on CD4-CD8- murine thymocytes. (1988) (41)
Expression of interleukin 1 receptors is restricted to the L3T4+ subset of mature T lymphocytes. (1987) (41)
Interleukin 2 enhancement of lymphokine secretion by T lymphocytes: analysis of established clones and primary limiting dilution microcultures. (1984) (41)
T Cell Receptor Specificity Is Critical for the Development of Epidermal γδ T Cells (2001) (41)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. I. Comparison of precursor frequencies for proliferative and cytolytic responses. (1979) (41)
Differential requirement for CD4 help in the development of an antigen-specific CD8+ T cell response depending on the route of immunization. (1998) (41)
Role of interleukin 1 in early T cell development: Lyt-2-L3T4- thymocytes bind and respond in vitro to recombinant IL 1. (1986) (41)
Differential requirements for the induction of interleukin 2 responsiveness in L3T4+ and Lyt-2+ T cell subsets (1985) (39)
Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli. (1988) (39)
Mouse interleukin-2 receptor alpha gene expression. Delimitation of cis-acting regulatory elements in transgenic mice and by mapping of DNase-I hypersensitive sites. (1995) (39)
The role of the T‐cell receptor (TCR) in αβ/γδ lineage commitment: clues from intracellular TCR staining (1998) (39)
Light scatter analysis and sorting of cells activated in mixed leukocyte culture. (1982) (38)
Phenotypic and functional properties of murine thymocytes. II. Quantitation of host- and donor-derived cytolytic T lymphocyte precursors in regenerating radiation bone marrow chimeras. (1982) (38)
Effect of hyperthermia on the functional activity of cytotoxic T-lymphocytes. (1977) (38)
Rat × Mouse T‐cell Hybrids with Inducible Specific Cytolytic Activity (1983) (38)
Allograft immunity in the mouse. 1. Quantitation and specificity of cytotoxic effector cells after in vitro sensitization. (1973) (37)
Paradigms of Notch Signaling in Mammals (2005) (37)
Selectively impaired development of intestinal T cell receptor γδ+ cells and liver CD4+ NK1+ T cell receptor αβ+ cells in T cell factor‐1‐deficient mice (1996) (37)
CD8+ T cells respond clonally to Mls-1a-encoded determinants (1990) (36)
Recombinant-derived interleukin-1α stabilized against specific deamidation (1987) (36)
Early detection of potentially lethal events in T cell‐mediated cytolysis (1975) (36)
Heterogeneity in P‐glycoprotein (multidrug resistance) activity among murine peripheral T cells: Correlation with surface phenotype and effector function (1994) (36)
Tissue-specific segregation of TCRgamma delta+ NKT cells according to phenotype TCR repertoire and activation status: parallels with TCR alphabeta+NKT cells. (2001) (36)
Skewed T cell receptor Vα repertoire among superantigen reactive murine T cells (1993) (36)
Recognition of protozoan parasites by murine T lymphocytes. II. Role of the H-2 gene complex in interactions between antigen-presenting macrophages and Leishmania-immune T lymphocytes. (1981) (35)
Cutting edge: influence of the TCR V beta domain on the avidity of CD1d:alpha-galactosylceramide binding by invariant V alpha 14 NKT cells. (2003) (35)
Phenotypic and functional characteristics of 'T-like' cells in nude mice. (1984) (34)
Limiting Dilution Analysis of Alloantigen-Reactive T Lymphocytes (1979) (34)
Dissociation of differentiation and proliferation in the primary induction of cytolytic T lymphocytes by alloantigens. (1980) (34)
Transgenic Expression of Ly49A on T Cells Impairs a Specific Antitumor Response1 (2000) (33)
A limited role for beta-selection during gamma delta T cell development. (1998) (33)
Abelson virus transformation of an interleukin 2-dependent antigen-specific T-cell line (1987) (33)
MHC class II hierarchy of superantigen presentation predicts efficiency of infection with mouse mammary tumor virus. (1994) (33)
Human Invariant Vα24-JαQ TCR Supports the Development of CD1d-Dependent NK1.1+ and NK1.1− T Cells in Transgenic Mice 1 (2003) (33)
Regulation of expression of T cell γ chain, L3T4 and Ly‐2 messages in Abelson/moloney virus‐transformed T cell lines (1988) (33)
Interleukin 2 production by lymphoid cells from congenitally athymic (nu/nu) mice. (1982) (32)
Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes (2013) (32)
Expression and presentation of endogenous mouse mammary tumor virus superantigens by thymic and splenic dendritic cells and B cells. (1996) (32)
Expression of B220 on activated T cell blasts precedes apoptosis (1998) (32)
The CD8 T cell response to staphylococcal enterotoxins. (1993) (32)
Cell surface glycoproteins involved in the stimulation of interleukin 1-dependent interleukin 2 production by a subline of EL4 thymoma cells. I. Functional characterization by monoclonal antibodies. (1985) (31)
Inhibition of mouse mammary tumor virus-induced T cell responses in vivo by antibodies to an open reading frame protein (1992) (31)
Cytolytic T lymphocyte clones that proliferate autonomously to specific alloantigenic stimulation. II. Relationship of the Lyt-2 molecular complex to cytolytic activity, proliferation, and lymphokine secretion. (1983) (31)
Thymic lineage commitment rather than selection causes genetic variations in size of CD4 and CD8 compartments. (1998) (30)
Serum potentiation of granulocyte and macrophage colony formation in vitro. (1975) (30)
Inducible Gene and shRNA Expression in Resident Hematopoietic Stem Cells In Vivo (2010) (30)
The tumor suppressor p16Ink4a regulates T lymphocyte survival (2006) (29)
CD1d–Glycolipid Tetramers: A New Tool to Monitor Natural Killer T Cells in Health and Disease (2000) (29)
In vivo T-lymphocyte tolerance in the absence of thymic clonal deletion mediated by hematopoietic cells. (1999) (28)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. V. Lyt phenotype of cytolytic T lymphocyte precursors reactive against normal and mutant H-2 antigens. (1981) (28)
Cultured Lyt-2- L3T4- T lymphocytes from normal thymus or lpr mice express a broad spectrum of cytolytic activity. (1986) (28)
TCRγ Silencing during αβ T Cell Development Depends upon Pre-TCR-Induced Proliferation (2006) (28)
Identification of the plasma membrane receptor for interleukin‐1 on mouse thymoma cells (1987) (27)
CD3-associated alpha/beta and gamma/delta heterodimeric receptors are expressed by distinct populations of CD4- CD8- thymocytes. (1988) (27)
Cytolytic T lymphocyte precursors reactive against mutant Kb alloantigens are as frequent as those reactive against a whole foreign haplotype. (1980) (27)
Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages. (1993) (26)
Increased cytolytic T lymphocyte activity induced by 2-mercaptoethanol in mixed leukocyte cultures: kinetics and possible mechanisms of action. (1976) (26)
Biased V beta usage in immature thymocytes is independent of DJ beta proximity and pT alpha pairing. (2001) (26)
Energy metabolism and T-cell-mediated cytolysis. II. Selective inhibition of cytolysis by 2-deoxy-D-glucose (1977) (26)
Frequency and specificity of precursors of interleukin 2-producing cells in nude mice. (1984) (25)
Peripheral clonal deletion of superantigen‐reactive T cells is enhanced by cortisone (1993) (25)
Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development. (1999) (25)
Monoclonal anti-Lyt-2 antibodies block the activation of cytolytic T lymphocyte precursors. (1983) (24)
A cortisone sensitive CD3low subset of CD4+CD8- thymocytes represents an intermediate stage in intrathymic repertoire selection. (1992) (24)
Expression of genes encoding cytotoxic cell-associated serine proteases in thymocytes. (1990) (24)
Cell surface glycoproteins involved in the stimulation of interleukin 1-dependent interleukin 2 production by a subline of EL4 thymoma cells. II. Structure, biosynthesis, and maturation. (1985) (23)
Inhibition of T cell‐mediated cytolysis by 2‐deoxy‐D‐glucose: dissociation of the inhibitory effect from glycoprotein synthesis (1979) (23)
Mechanisms of immunological tolerance. (1989) (23)
c-Myc controls the development of CD8alphaalpha TCRalphabeta intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. (2010) (23)
The mouse Lyt-2/3 antigen complex--I. Mode of association of the subunits with the membrane. (1984) (23)
Analysis of Immature (CD4–CD8–) Thymic Subsets in T-Cell Receptor αß Transgenic Mice (1992) (23)
T cell recognition of superantigens. (1991) (23)
In vitro negative selection of viral superantigen-reactive thymocytes by thymic dendritic cells. (1997) (23)
Generation of cytotoxic T lymphocytes in vitro. VI. Effect of cell density on response in mixed leukocyte cultures. (1975) (22)
Cytolytic T lymphocyte function is independent of growth phase and position in the mitotic cycle (1981) (22)
A critical role for the T cell receptor α‐chain connecting peptide domain in positive selection of CD1‐independent NKT cells (2001) (22)
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development (2001) (22)
Development and Selection of Vα14i NKT Cells (2007) (22)
Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin. (1999) (22)
Cd1d–Glycolipid Tetramers (2000) (22)
Preparation, characterization and application of interleukin-1 beta mutant proteins with surface-accessible cysteine residues. (1989) (22)
Lysis of tumor cells by the retargeting of murine cytolytic T lymphocytes with bispecific antibodies (1987) (21)
A Comparison of the Effector Cells Involved in Cell‐Mediated Lympholysis and Antibody‐Dependent Cell‐Mediated Cytotoxicity in Man (1975) (21)
Intrathymic differentiation: Some unanswered questions (1985) (21)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. VI. Ontogeny of cytolytic T lymphocyte precursors in the thymus. (1981) (20)
Flow cytofluorometric analysis of the binding of Vicia villosa lectin to T lymphoblasts: lack of correlation with cytolytic function. (1981) (20)
THE MULTICELLULAR SPHEROID AS A MODEL TUMOR ALLOGRAFT: I. QUANTITATIVE ASSESSMENT OF SPHEROID DESTRUCTION IN ALLOIMMUNE MICE (1978) (20)
Constitutive Expression of a Chimeric Receptor That Delivers IL-2/IL-15 Signals Allows Antigen-Independent Proliferation of CD8+CD44high But Not Other T Cells1 (2000) (20)
Cytolytic T lymphocyte clones. (1982) (20)
Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells (1995) (19)
Survival-independent function of NF-kappaB/Rel during late stages of thymocyte differentiation. (1998) (19)
T cell receptor Vβ repertoire in mice lacking endogenous mouse mammary tumor provirus (1995) (19)
N‐terminal‐methionylated interleukin‐1β has reduced receptor‐binding affinity (1987) (19)
Biosynthesis and maturation of the Lyt-2/3 molecular complex in mouse thymocytes. (1985) (19)
Direct transfer of antigen-specific cytolytic activity to noncytolytic cells upon fusion with liposomes derived from cytolytic T cell clones (1984) (19)
The murine interleukin‐2 receptor γ chain gene: Organization, chromosomal localization and expression in the adult thymus (1994) (19)
Expression of T cell receptor genes in the thymus: localization of transcripts in situ and comparison of mature and immature subsets (1990) (18)
Suppressor T cells regulate the cytolytic T lymphocyte response to syngeneic tumors induced by murine sarcoma virus (MSV) in the mouse. (1979) (18)
Structural homology between the human 4F2 antigen and a murine cell surface glycoprotein associated with lymphocyte activation. (1986) (18)
Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells. (1987) (18)
Inhibition of cytolytic T lymphocyte clones reactive with Moloney leukemia virus-associated antigens by monoclonal antibodies: a direct approach to the study of H-2 restriction. (1981) (17)
Stimulator requirements for primed alloreactive T cells: macrophages and dendritic cells activate T cells across all genetic disparities. (1985) (17)
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation (2018) (17)
Development and selection of Valpha l4i NKT cells. (2007) (17)
Effect of delayed addition of 2‐mercaptoethanol on the generation of mouse cytotoxic T lymphocytes in mixed leukocyte cultures (1975) (17)
Flow-microfluorometric monitoring of oligoclonal CD8+ T cell responses to an immunodominant Moloney leukemia virus-encoded epitope in vivo. (1998) (17)
Quantitation of endogenous mouse mammary tumor virus superantigen expression by lymphocyte subsets (1995) (17)
An Adult Thymic Stromal-Cell Suspension Model for in Vitro Positive Selection (1998) (16)
Homeostasis limits the development of mature CD8+ but not CD4+ thymocytes. (1998) (16)
CD8+ T cell response to Mls-1a determinants involves major histocompatibility complex class II molecules (1991) (16)
Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. (2003) (16)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. III. Effect of priming on precursor frequencies. (1979) (16)
Developmentally regulated expression of P‐glycoprotein (multidrug resistance) activity in mouse thymocytes (1995) (16)
NKT cells: In the beginning… (2007) (16)
Limiting dilution analysis of alloantigen-reactive T lymphocytes. IV. High frequency of cytolytic T lymphocyte precursor cells in MLC blasts separated by velocity sedimentation. (1980) (15)
T cell receptor delta gene rearrangement and T early alpha (TEA) expression in immature alpha beta lineage thymocytes: implications for alpha beta/gamma delta lineage commitment. (1996) (15)
Multicellular tumor spheroids of human colon carcinoma origin. Kinetic analysis of infiltration and in situ destruction in a xenogeneic (murine) host. (1981) (15)
Superantigen as suspect (1994) (15)
Primary generation of cytolytic T lymphocytes in the absence of DNA synthesis (1979) (15)
Characterization of effector lymphocytes associated with immunity to murine sarcoma virus (MSV) induced tumors. I. Physical properties of cytolytic T lymphocytes generated in vitro and of their immediate progenitors. (1976) (15)
T Before NK (2002) (15)
Ly49D Engagement on T Lymphocytes Induces TCR-Independent Activation and CD8 Effector Functions That Control Tumor Growth1 (2009) (14)
Regulation of the rate of cell cycle progression in quiescent cytolytic T cells by T cell growth factor: Analysis by flow microfluorometry (1984) (14)
Lack of directed V alpha 14-J alpha 281 rearrangements in NK1+ T cells. (1997) (14)
Absolute requirement for the pre-T cell receptor alpha chain during NK1.1+ TCRalphabeta cell development. (1999) (14)
Cutting Edge: Cell Autonomous Rather Than Environmental Factors Control Bacterial Superantigen-Induced T Cell Anergy In Vivo1 (2000) (13)
Phorbol ester enhances both interleukin 2 receptor expression and immunoglobulin secretion in human Epstein‐Barr virus‐immortalized B cells (1986) (13)
Generation of thymocyte subpopulations in organ culture: correlated analysis of Lyt-2 phenotype and cell cycle status by flow microfluorometry. (1983) (13)
CD4+8- thymocytes bearing major histocompatibility complex class I- restricted T cell receptors: evidence for homeostatic control of early stages of CD4/CD8 lineage development (1992) (13)
TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation. (2006) (13)
NK cell tolerance: revisiting the central dogma (2005) (13)
Variable requirement for murine lymphocyte function-associated antigen-1 (LFA-1) in T cell-mediated lysis depending upon the tissue origin of the target cells. (1985) (12)
Generation of cytolytic T lymphocytes in vitro. (1976) (12)
Cell Separation Analysis of B and T Lymphocyte Differentiation (1975) (12)
Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts. (2011) (12)
Functional Education of Invariant NKT Cells by Dendritic Cell Tuning of SHP-1 (2013) (12)
Notch 1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells (2000) (12)
The multicellular spheroid as a model tumor allograft. III. Morphological and kinetic analysis of spheroid infiltration and destruction. (1980) (12)
The multicellular tumor spheroid: a quantitative model for studies of in situ immunity. (1980) (11)
Comparison of phorbol‐12‐myristate‐13‐acetate and dioctanoyl‐sn‐glycerol in the activation of EL4/6.1 thymoma cells (1989) (10)
Effect of transforming growth factor beta on the EL4 thymoma variant EL4/6.1: dissociation of inhibition of proliferation from expression of IL-1 and IL-2 receptors. (1990) (10)
Selective expression of Vδ6 genes by B2A2− CD4− CD− T cell receptor γ/δ thymocytes (1990) (9)
Studies on the Distribution and Origin of Cytolytic T Lymphocytes Present in Mice Bearing Moloney Murine Sarcoma Virus (MSV)-lnduced Tumors1 (1976) (9)
Retargeting of cytolytic T lymphocytes by heteroaggregated (bispecific) antibodies. (1988) (9)
T cell receptor (TcR) beta chain transgenic mice: studies on allelic exclusion and on the TcR+ gamma/delta population. (1990) (9)
Cell surface phenotype of cytolytic T lymphocyte precursors in aged nude mice (1981) (9)
Neonatal tolerance to MIs-1a determinants: deletion or anergy of V beta 6+ T lymphocytes depending upon MHC compatibility of neonatally injected cells. (1991) (9)
TCR-α CDR3 Loop Audition Regulates Positive Selection1 (2006) (9)
Heterogeneity of inhibition of cytolytic T lymphocyte clones by monoclonal anti-Lyt-2/3 antibodies: parallel effects on cytolysis, proliferation and lymphokine secretion. (1982) (8)
T cell recognition of lipids: quo vadis? (2007) (8)
Selective expansion of activated Vδ4+ cells during experimental infection of mice with Leishmania major (1994) (8)
Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo. (1999) (8)
A Limited Role for b-Selection During gd T Cell Development (1998) (8)
DL4‐mediated Notch signaling is required for the development of fetal αβ and γδ T cells (2013) (8)
Antibody-dependent Cell-mediated Destruction of Human Erythrocytes Sensitized in ABO and Rhesus Fetal-Maternal Incompatibilities (1976) (8)
Hierarchal Utilization of Different T-Cell Receptor Vβ Gene Segments in the CD8+-T-Cell Response to an Immunodominant Moloney Leukemia Virus-Encoded Epitope In Vivo (1999) (8)
Inhibition of clone formation as an assay for T cell-mediated cytotoxicity: short-term kinetics and comparison with 51Cr release. (1977) (7)
Dissociation of interleukin 2‐dependent and ‐independent B cell proliferation with monoclonal anti‐interleukin 2 receptor antibody (1986) (7)
T cell repertoire selection during development. (1989) (7)
Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells. (1990) (7)
Restimulation of cytolytic T-lymphocytes in long-term mixed leukocyte cultures. 1. Physical and proliferative characteristics of cytolytic T-lymphocytes restimulated at low cell density. (1978) (7)
Virus-Encoded Epitope In Vivo Immunodominant Moloney Leukemia (1998) (7)
Lymphoid environment limits superantigen and antigen‐induced T cell proliferation at high precursor frequency (2001) (7)
A Limited Role for β-Selection During γδ T Cell Development (1998) (7)
Antibody-dependent cellular cytotoxicity in cancer patients: lack of prognostic value (1980) (7)
In vitro negative selection of viral superantigen-reactive TCR transgenic thymocytes by thymic dendritic cells (1997) (7)
Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for V alpha 8-, V beta 2- or V beta 10-bearing T cells. (1991) (6)
Antigen recognition by H-2-restricted cytolytic T lymphocytes is not mediated by two independent receptors (1984) (6)
TCR-alpha CDR3 loop audition regulates positive selection. (2006) (6)
Fate of potentially self-reactive T cells in neonatal mice: analysis of V beta 6+ T cells in Mlsa mice. (1989) (6)
Anti‐Thy‐1‐induced proliferation of immature thymocytes expressing the CD3‐associated γ/δ heterodimer (1987) (6)
Reversible Changes in Cytolytic T Lymphocyte Function Induced by Hyperthermia (1978) (6)
Inhibition of T cell-mediated cytolysis by 2-deoxy-D-glucose (2-DG): differential effect of 2-DG on effector cells isolated early or late after alloantigenic stimulation in vitro. (1979) (6)
Selective absence of CD8+ TCRα β+ intestinal epithelial cells in transgenic mice expressing β2‐microglobulin‐associated ligands exclusively on thymic cortical epithelium (2003) (6)
Viral superantigen-induced negative selection of TCR transgenic CD4+ CD8+ thymocytes depends on activation, but not proliferation. (1998) (6)
Different structural constraints for recognition of mouse H-2Kd and -Kk antigens by alloimmune cytolytic T lymphocytes (1986) (6)
Development and function of natural killer 1+ T-cells. (1997) (6)
16 – Growth Regulation of Cytolytic T Cell Lines by Interleukin-2 (1982) (5)
T CELL ANTIGEN RECEPTOR EXPRESSION IN ATHYMIC (1987) (5)
Subversion of host immune responses by viral superantigens. (1993) (5)
cell self-renewal and differentiation Jagged1 dependent Notch signaling is dispensable for hematopoietic stem (2013) (5)
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO (1974) (5)
Expression of Natural Resistance in Immune-Deficient Animals (1984) (5)
The need for natural killer T cells (2005) (5)
Ly49D-Mediated ITAM Signaling in Immature Thymocytes Impairs Development by Bypassing the Pre-TCR Checkpoint (2011) (5)
c-Myc controls the development of CD 8 TCR intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15 – dependent survival (2010) (5)
Differentiation of cytolytic T lymphocytes (1992) (5)
The Cis-Acting Elements Controlling Mouse IL-2Rα Transcription (1995) (5)
Skewed T cell receptor V alpha repertoire among superantigen reactive murine T cells. (1993) (5)
Activation requirements for resting T lymphocytes. (1986) (5)
Clonogenic potential of murine CD4+8+ thymocytes. Direct demonstration using a V beta 6-specific proliferative stimulus in Mlsa mice. (1989) (5)
Functional responsiveness in vitro and in vivo of alpha/beta T cell receptors expressed by the B2A2 (J11d)- subset of CD4-8- thymocytes. (1989) (5)
Tolerance to Mlsa by clonal deletion of V beta 6+ T cells in bone marrow and thymus chimeras. (1989) (5)
Macrophage activation in vitro by lymphocytes from Leishmania major infected healer and non‐healer mice (1988) (5)
Inducible gene expression in fetal thymic epithelium: A new BAC transgenic model (2013) (5)
Viral Superantigen-Induced Negative Selection of TCR Transgenic CD4 + CD8 + Thymocytes Depends on Activation, but not Proliferation (1998) (4)
Development of T-Dependent Immune Function in Nude Mice (1987) (4)
The Generation, Detection and Characterization of Cytotoxic T Lymphocyte Activity in Vitro (1976) (4)
Interleukin-2 production by lymphoid cells from nude mice. A comparison of bulk culture and limiting dilution analysis. (1984) (4)
Clonal Deletion of Autoreactive T Lymphocytes: Insights from Neonatal Ontogeny (1989) (4)
Pairing of Vβ6 with certain Vα2 family members prevents T cell deletion by Mtv-7 superantigen (2000) (4)
Superantigen-reactive CD 4 + T Cells Are Required to Stimulate B Cells after Infection with Mouse Mammary Tumor Virus (2003) (4)
LACK‐reactive CD4+ T cells require autocrine IL‐2 to mediate susceptibility to Leishmania major (2006) (4)
Pairing of Vbeta6 with certain Valpha2 family members prevents T cell deletion by Mtv-7 superantigen. (2000) (3)
Development and localization of 'T-like' cells in the nude mouse. (1984) (3)
Deletion versus anergy: the superantigen paradigm. (1992) (3)
Allograft Immunity in the Mouse (1973) (3)
Expression of T‐Cell Receptors by Functionally Distinct Subsets of Immature Adult Thymocytes (1988) (3)
Studies on the distribution and origin of cytolytic T lymphocytes present in mice bearing Moloney murine sarcoma virus (MSV)-induced tumors. (1975) (3)
Separation of earthworm coelomocytes by velocity sedimentation. (1979) (3)
CD 8 + T Cell Response to Mls-1 a Determinants Involves Major Histocompatibility Complex Class II Molecules By (3)
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO (1974) (3)
The interleukin-1/interleukin-1-receptor interaction. (1987) (3)
Immunology. T before NK. (2002) (3)
Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells (2016) (2)
Selective expression of V delta 6 genes by B2A2- CD4- CD8- T cell receptor gamma/delta thymocytes. (1990) (2)
Distinct effects of phorbol esters and exogenous diacylglycerols in the induction of murine thymocyte proliferation (1992) (2)
N-terminal-methionylated interleukin-1 beta has reduced receptor-binding affinity. (1987) (2)
Does negative selection involve accumulation of self-reactive thymocytes in thymic rosettes? (1991) (2)
Recombinant-derived interleukin-1 alpha stabilized against specific deamidation. (1987) (2)
Ribonuclease inhibitor (RNH1) is a ribosome-associated protein and regulates erythropoiesis by controlling GATA1-specific mRNA translation (2017) (2)
Iphibition of Mouse Manunary Tumor Virus-induced T Cell Responses In Vivo by Antibodies to an Open Reading Frame Protein By Hans Acha-Orbea, Leonardo Scarpdlino, Alexander N. Shakhov, (1992) (1)
Effect of interleukin-2 on murine and human B cells (1984) (1)
The definition of lymphocyte subpopulations: new approaches to an old problem. (1984) (1)
CD4/CD8 lineage commitment in T cell receptor transgenic mice: evidence for precommitment of CD4+ CD8+ thymocytes. (1994) (1)
Molecular mechanism of t-cell-mediated cytotoxicityIntroduction (1987) (1)
Thymocytes + But Not CD 4 + CD 8 Homeostasis Limits the Development of Mature MacDonald (1998) (1)
Formation of cytotoxic lymphocytes in mixed leukocyte culture systems: introduction. (1973) (1)
Mouse Interleukin-2 Receptor Gene Expression (1995) (1)
Positive and negative selection of the T-cell antigen receptor repertoire in nontransgenic mice. (1989) (1)
Heterogeneity of lymphokine production by murine T-lymphocyte clones. (1982) (1)
A critical lineage‐nonspecific role for pTα in mediating allelic and isotypic exclusion in TCRβ‐transgenic mice (2007) (1)
Membrane Proteins of Murine T Cell Clones (1982) (1)
Alloreactive cytolytic T lymphocyte precursor cells in aged C57Bl/6 nu/nu mice: frequency and cell surface phenotype. (1984) (1)
Ontogeny of murine thymus cells: correlation of surface phenotype with the appearance of cytolytic T lymphocyte precursors. (1982) (1)
A critical lineage-nonspecific role for pTalpha in mediating allelic and isotypic exclusion in TCRbeta-transgenic mice. (2007) (1)
Cloning of Functional T Lymphocytes (1984) (1)
24 – Cytolytic T Lymphocyte Clones Recognizing Murine Sarcoma Virus-Induced Tumor Antigens (1982) (1)
Introduction: notch and lymphopoiesis (2003) (1)
Selective absence of CD8+ TCRalpha beta+ intestinal epithelial cells in transgenic mice expressing beta2-microglobulin-associated ligands exclusively on thymic cortical epithelium. (2003) (1)
Diabetes. Superantigen as suspect. (1994) (1)
Notch Repression by LRF Is Necessary for the Maintenance of Adult Hematopoietic Stem Cell Pool. (2010) (1)
An Unexpected Role for Ribonuclease Inhibitor (RNH1) in Erythropoiesis (2014) (1)
Interleukins (IL)-1 and IL-2 control IL-2 receptor alpha and beta expression in immature thymocytes. (1994) (1)
CD8+ T cell development: CD4 to the rescue (2001) (1)
University of Birmingham Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 mRNA translation (2018) (1)
Impairs a Specific Antitumor Response Transgenic Expression of Ly49A on T Cells (2000) (1)
Autoreactivity of hybrids putatively derived from immature CD4+CD8+V beta 6+ thymocytes from an Mlsa mouse. (1989) (0)
Characterization of anti-MSV cytotoxic lymphocytes generated in secondary mixed leukocyte-tumor cell cultures (1976) (0)
lymphopoiesis -catenin does not perturb hematopoiesis or γ - and β Simultaneous loss of (2013) (0)
Title : Disrupting the EMMPRIN ( CD 147 )-cyclophilin A interaction reduces infarct size and preserves systolic function after myocardial ischemia and reperfusion (0)
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Production of macrophage activating factor by cytolytic and noncytolytic T lymphocyte clones. (1982) (0)
Cell Divisions In Vivo Preferentially After a Discrete Number of Superantigen-Activated T Cells Occurs Cutting Edge : Apoptosis of (1999) (0)
Anti-Thy-1-induced proliferation of immature thymocytes expressing the CD3-associated gamma/delta heterodimer. (1987) (0)
Cytotoxic T Cells Class I- Dependent Lymphocyte Killing by NLRC5 Deficiency Selectively Impairs MHC (2012) (0)
by Bypassing the Pre-TCR Checkpoint Immature Thymocytes Impairs Development Ly49D-Mediated ITAM Signaling in (2017) (0)
Growth CD 8 Effector Functions That Control Tumor Induces TCR-Independent Activation and Ly 49 D Engagement on T Lymphocytes (2008) (0)
Novel Monoclonal Antibodies Development and Activation Revealed by Surface Expression during T Cell Dynamic Regulation of Notch 1 and Notch 2 (2009) (0)
Precommitment of CD 4 + CD 8 + thymocytes to either CD 4 or CD 8 lineages (2005) (0)
Granzyme A Is an Interleukin 13-converting E n z y m e By (2003) (0)
Thymus-Independent and-Dependent T Cells in the Development of Both Cutting Edge : An Essential Role for Notch-1 Freddy (2000) (0)
Negative Selection of V for Thymocytes and Thymic APCs in Positive Transgenic Mice Reveals Independent Roles Targeted Expression of Human CD 1 d in MacDonald (2005) (0)
Requirement for Lyt-2/3 molecules on allospecific cytolytic T lymphocyte clones is dependent upon target cell antigen density. (1985) (0)
V alpha 14 NKT cells--a novel lymphoid cell lineage. (1997) (0)
1 + T Cell Receptor-a / E + Cells : N e w Their Origin , Specificity , and Function (2003) (0)
by Cells of Hemopoietic Origin Requires MHC Class II Antigen Expression Protection from Radiation-Induced Colitis (1999) (0)
Selective Lysis of Activated Cells in Oncorna Virus Infection (1997) (0)
Separation and Characterization of Subpopulations of T Cells (1987) (0)
H . Robson In Vivo Moloney Leukemia Virus-Encoded Epitope-T-Cell Response to an Immunodominant + Gene Segments in the CD 8 β Receptor V Hierarchal Utilization of Different T-Cell (1999) (0)
Development of New and Combined Immune Defects (1984) (0)
Numblike the Combined Absence of Numb and Normal Hemopoiesis and Lymphopoiesis in MacDonald and (2007) (0)
Molecule function on cytolytic t lymphocytes analysis using antigen inducible allogeneic targets (1985) (0)
Numblikethe Combined Absence of Numb and Normal Hemopoiesis and Lymphopoiesis in (2007) (0)
INTERLEUKIN 2 IS A B CELL GROWTH (2003) (0)
Erratum: Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia (Nature Immunology (2010) 11 (717-724)) (2010) (0)
The cis-acting elements controlling mouse IL-2R alpha transcription. (1995) (0)
Clonal analysis of the T lymphocyte response to murine sarcoma virus-induced tumors. (1982) (0)
Epithelial Cells Delta-Like 4 Expression on Cortical Cutting Edge : Thymic Crosstalk Regulates (2008) (0)
homeostasis c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell (2011) (0)
EFFECT OF REPEATED EXPOStrRE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES* BY H. ROBSON MACDONALD,~t HOWARD D. ENGERS,$ JEAN-CHARLES CEROTTINI, AND K. THEODOR BRUNNER (2003) (0)
Superantigens in disease (2005) (0)
ENERGY METABOLISM AND T-CELL-MEDIATED CYTOLYSIS I. Synergism between Inhibitors of Respirat ion and Glycolysis* (2003) (0)
T CELL RECEPTORS IN NUDE MICE (2003) (0)
Biochemical characterization of a T-lymphoma-specific 90,000 molecular weight disulfide linked dimeric glycoprotein. (1987) (0)
Both Lyt2+ and L3T4+ Cell Subsets Secrete the Serine Esterase Granzyme A in Response to a Specific Antigenic Stimulus (1988) (0)
Nki.1 + T Cell Receptor-a/e + Cells: New Their Origin, Specificity, and Function Phenotype and Tcr Expression of Nki + T Cells (2003) (0)
T Cells Induce Colitis in Immunodeficient RAG Hosts (2001) (0)
Non Antigen-Specific Surface Molecules Involved in T Lymphocyte Function (1985) (0)
T Cell Response In Vivo + Polymorphism on an Antigen-Specific CD8 Gene b Dramatic Influence of V (1999) (0)
LRF Maintains HSC Homeostasis by Preventing Lymphoid-Primed LT-HSCs From Excessive Differentiation (2011) (0)
Image analysis of cell proliferation and differentiation in the thymus of the newt by Samba 200 cell image processor (2008) (0)
Stringent V ~ 3 Requirement for the Deve lopment o f NKI . 1 + T Cell Receptor-- cx / ~ + Cells in Mouse Liver (2003) (0)
NLRC5 deficiency impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells (2012) (0)
hematopoietic stem cell maintenance LRF-mediated Dll4 repression in erythroblasts is necessary for (2013) (0)
TRANSFER OF SPECIFIC CYTOLYTIC ACTIVITY BY LIPOSOMES (2003) (0)
CD4 and CD8 Compartments Selection Causes Genetic Variations in Size of Thymic Lineage Commitment Rather Than (1998) (0)
Frequency and Lyt phenotype of lymphokine-secreting murine T-lymphocyte clones☆☆☆ (1982) (0)
T Cell Receptor Speciﬁcity Is Critical for the Development of Epidermal (cid:2)(cid:3) T Cells (2001) (0)
Forum in immunology. XVII: Molecular mechanism of T-cell-mediated cytotoxicity (1987) (0)
Cytolytic T lymphocytes (CTL) 1 recognize a wide variety of antigens cross-reacting with those against which the immune population was originally sensitized (1). Definitive analysis of this cross-reactivity requires examination of the killing specificity (1980) (0)
NKCD 1 d-Dependent and CD 1 d-Independent Tissue-Specific Segregation of Taniguchi (1999) (0)
Table of Contents (1987) (0)
Quantitative approaches to the assessment of cell-mediated immune responses to solid tumor allografts. (1978) (0)
Brief DeNnitive Report (2003) (0)
Erratum: T cell recognition of lipids: quo vadis? (2007) (0)
Positive Selection CDR 3 Loop Audition Regulates α TCR-Simpson (2006) (0)
NKT Cells by Endogenous Ligands Domain on the Selection of Semi-Invariant β Cutting Edge : Influence of the TCR V Casorati (2006) (0)
II. EFFECT OF REPEATED EXPOStrRE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES* (1974) (0)
ENERGY METABOLISM AND T-CELL-MEDIATED CYTOLYSIS (2003) (0)
Brief Definitive Report Differential Requirements for the Induction of Interleukin 2 Responsiveness in L3t4 + and Lyt-2 + T Cell Subsets (0)
by Dendritic Cell Tuning of SHP-1 Functional Education of Invariant NKT Cells (2013) (0)

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