Hamao Umezawa

Q: What Schools Are Affiliated With Hamao Umezawa

Hamao Umezawa is affiliated with the following schools: Fujita Health University, Gunma University

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Hamao Umezawa

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Chemistry

Hamao Umezawa's Degrees

PhD Chemistry University of Tokyo

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Hamao Umezawa's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

New antibiotics, bleomycin A and B. (1966) (696)
Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. (1976) (662)
Pepstatin, a new pepsin inhibitor produced by Actinomycetes. (1970) (600)
Structures and activities of protease inhibitors of microbial origin. (1976) (415)
Formation and reversion of Streptomycete protoplasts: cultural condition and morphological study. (1974) (316)
On the mechanism of action of bleomycin: scission of DNA strands in vitro and in vivo. (1969) (300)
Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus (1986) (240)
Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3. (1986) (212)
A new antitumor antibiotic, spergualin: isolation and antitumor activity. (1981) (202)
Low-molecular-weight enzyme inhibitors of microbial origin. (1982) (196)
Mechanism of action of bleomycin. Studies with the growing culture of bacterial and tumor cells. (1968) (182)
Enzyme inhibitors of microbial origin (1972) (181)
Tetrahydropyranyl derivatives of daunomycin and adriamycin. (1979) (181)
Studies on bleomycin (1969) (181)
Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. (1984) (175)
Studies on the mechanism of antitumor effect of bleomycin of squamous cell carcinoma. (1972) (174)
Purification of bleomycins. (1966) (170)
Production and isolation of a new antibiotic: kanamycin. (1957) (167)
Screening of agents which convert 'transformed morphology' of Rous sarcoma virus-infected rat kidney cells to 'normal morphology': identification of an active agent as herbimycin and its inhibition of intracellular src kinase. (1985) (158)
A THERMOLYSIN INHIBITOR PRODUCED BY ACTINOMYCETES: PHOSPHORAMIDON (1973) (157)
Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes. (1972) (146)
Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase. (1976) (142)
Activity and toxicity of bleomycin. (1967) (138)
Inhibition of DNA-dependent RNA synthesis by rifamycins. (1968) (137)
ON THE MECHANISM OF ACTION OF BLEOMYCIN (1970) (133)
Letter: Syntheses of 1-n-(S)-4-amino-2-hydroxybutyryl)-kanamycin B and -3', 4'-dideoxykanamycin B active against kanamycin-resistant bacteria. (1973) (131)
The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNA. (1969) (130)
Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor. (1967) (129)
Ascorbic acid and adriamycin toxicity. (1991) (127)
The structure of bestatin. (1976) (127)
Effect of bestatin on mouse immune system and experimental murine tumors. (1980) (125)
Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud. (1976) (125)
Chemistry of bleomycin. XXI. Metal-complex of bleomycin and its implication for the mechanism of bleomycin action. (1978) (123)
New antifungal antibiotics, benanomicins A and B from an actinomycete. (1988) (122)
Chemistry of bleomycin. XX. The X-ray structure determination of P-3A Cu(II)-complex a biosynthetic intermediate of bleomycin. (1978) (121)
3',4'-dideoxy-kanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa. (1971) (120)
GHYMOSTATIN, A NEW GHYMOTRYPSIN INHIBITOR PRODUCED BY ACTINOMYGETES (1970) (117)
Bleomycin and other antitumor antibiotics of high molecular weight. (1965) (117)
Structure of an antitumor antibiotic, spergualin. (1981) (112)
Antitumor anthracycline antibiotics, aclacinomycin a and analogues. II. Structural determination. (1979) (100)
The structure of pepstatin. (1970) (99)
Natural and artificial bleomycins: chemistry and antitumour activities (1971) (98)
Biochemical mechanism of resistance to aminoglycosidic antibiotics. (1974) (98)
NEW ANTIBIOTICS, BLEOMYCIN A & B (1966) (98)
ANTITUMOR ANTHRACYCLINE ANTIBIOTICS, ACLACINOMYCIN A AND ANALOGUES (1979) (97)
A bleomycin-inactivating enzyme in mouse liver. (1974) (96)
The structure of aquayamycin. (1970) (96)
Breaks and rejoining of DNA in cultured mammalian cells treated with bleomycin. (1970) (95)
Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes. (1973) (93)
Serum dopamine β-hydroxylase activity in developing hypertensive rats (1974) (91)
Decrease of melting temperature and single strand scission of DNA by bleomycin in the presence of 2-mercaptoethanol. (1969) (90)
The structural studies of formycin and formycin B. (1966) (89)
Studies on bleomycin: chemistry and the biological action. (1973) (88)
Bleomycin : current status and new developments (1978) (87)
Negamycin, a novel hydrazide antibiotic. (1971) (87)
Reduction of adriamycin toxicity by ascorbate in mice and guinea pigs. (1982) (87)
Possible control of formation of aerial mycelium and antibiotic production in Streptomyces by episomic factors. (1970) (86)
Chemistry of bleomycin. XVIII. carbon-13 NMR studies. (1977) (86)
Mannostatins A and B: new inhibitors of alpha-D-mannosidase, produced by Streptoverticillium verticillus var. quintum ME3-AG3: taxonomy, production, isolation, physico-chemical properties and biological activities. (1989) (85)
Synthesis and antitumor activity of spergualin analogues. I. Chemical modification of 7-guanidino-3-hydroxyacyl moiety. (1985) (85)
Chemistry and mechanism of action of bleomycin. (1974) (84)
An active intermediate formed in the reaction of bleomycin-Fe(II) complex with oxygen. (1981) (84)
Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes. (1985) (84)
A plasmid involved in chloramphenicol production in Streptomyces venezuelae: evidence from genetic mapping. (1975) (84)
Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces. (1974) (83)
Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination. (1987) (82)
Antitumor activity of new anthracycline antibiotics, aclacinomycin-A and its analogs, and their toxicity. (1977) (81)
Index of antibiotics from actinomycetes (1967) (81)
A new antibiotic, azomycin. (1953) (81)
Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E. coli. (1967) (80)
Synthesis of (-)-15-deoxyspergualin and (-)-spergualin-15-phosphate. (1982) (79)
Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. I. Taxonomy, production, isolation and preliminary characterization. (1986) (78)
Rapid uptake by cultured tumor cells and intracellular behavior of 4'-O-tetrahydropyranyladriamycin. (1983) (77)
Mitogenic effect of bestatin on lymphocytes. (1980) (75)
Recent advances in bioactive microbial secondary metabolites. (1977) (75)
New aminoglycoside antibiotics, istamycins A and B. (1979) (74)
A glyoxalase I inhibitor of a new structural type produced by Streptomyces. (1975) (73)
Lethal effect of bleomycin on cultured mammalian cells. (1970) (72)
Adenylylstreptomycin, a product of streptomycin inactivated by E. coli carrying R factor. (1968) (71)
Binding of bleomycin to DNA in bleomycin-sensitive and -resistant rat ascites hepatoma cells. (1975) (71)
Structures of new antibiotics napyradiomycins. (1986) (70)
Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological properties. (1987) (70)
Esterastin, an inhibitor of esterase, produced by actinomycetes. (1978) (68)
The total syntheses of negamycin and the antipode. (1972) (67)
Effect of bleomycin on mammalian cell survival. (1972) (67)
Studies on auromomycin. (1979) (67)
A NEW ANTIBIOTIC, KASUGSMYCIN. (1965) (64)
Properties and specificity of binding sites for the immunomodulator bestatin on the surface of mammalian cells. (1982) (64)
Chemistry of bleomycin. XXII. Interaction of bleomycin with nucleic acids, preferential binding to guanine base and electrostatic effect of the terminal amine. (1978) (64)
Biological studies on bleomycin A. (1967) (64)
Suppression of tissue graft rejection by spergualin. (1985) (64)
Structure of antipain, a new Sakaguchi-positive product of streptomyces. (1972) (63)
Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa. (1968) (62)
Immunosuppressive activities of 15-deoxyspergualin in animals. (1987) (62)
Phosphorylation and inactivation of aminoglycosidic antibiotics by E. coli carrying R factor. (1968) (62)
The structure of chymostatin, a chymotrypsin inhibitor. (1973) (61)
Decrease of melting temperature and single strand scission of DNA by bleomycin in the presence of hydrogen peroxide. (1969) (61)
Inhibition of DNA-dependent RNA polymerase reaction of Escherichia coli by an antimicrobial antibiotic, streptovaricin. (1968) (60)
Isolation and structure of a new antibiotic, indolizomycin, produced by a strain SK2-52 obtained by interspecies fusion treatment. (1984) (60)
Biological studies on individual bleomycins. (1968) (60)
Proteinase inhibitors : medical and biological aspects (1983) (59)
Modes of action of phleomycin, bleomycin and formycin on HeLa S3 cells in synchronized culture. (1967) (59)
Production of nineteen anthracyclic compounds by Streptomyces galilaeus MA144-M1. (1977) (59)
The effect of bleomycin on SV40 DNA: characteristics of bleomycin action which produces a single scission in a superhelical form of SV40 DNA. (1973) (58)
Kinetic studies of tyrosine kinase inhibition by erbstatin. (1987) (58)
Structure and action of bleomycin. (1976) (58)
REACTION OF BLEOMYCIN WITH DNA (1971) (58)
Structures and Syntheses of Leupeptins Pr-LL and Ac-LL (1969) (57)
Studies on adenylylstreptomycin, a product of streptomycin inactivation by E. coli carrying the R-factor. (1968) (57)
Synthetic analogues and biosynthetic intermediates of bleomycin. Metal-binding, dioxygen interaction, and implication for the role of functional groups in bleomycin action mechanism. (1983) (57)
Letter: Kanamycin phosphotransferase. I. Mechanism of cross resistance between kanamycin and lividomycin. (1973) (57)
Mode of inhibition of coformycin on adenosine deaminase. (1967) (56)
Identification and properties of the cell membrane bound leucine aminopeptidase interacting with the potential immunostimulant and chemotherapeutic agent bestatin. (1983) (56)
Intracellular reduction of the cupric ion of bleomycin copper complex and transfer of the cuprous ion to a cellular protein. (1977) (56)
Isolation and structure of a beta-lactamase inhibitor from Streptomyces. (1977) (55)
Isolation and characterization of terpentecin, a new antitumor antibiotic. (1985) (54)
Biosynthesis of napyradiomycins. (1987) (54)
Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor. (1968) (54)
Inhibition of dopamine beta-hydroxylase by 5-alkylpicolinic acid and their hypotensive effects. (1969) (54)
REDUCTIVE CLEAVAGE OF ANTHRA-CYCLINE GLYCOSIDES BY MICROSOMAL NADPH-CYTOCHROME C REDUCTASE (1977) (53)
Influence of formycin B on polyadenosine diphosphoribose synthesis in vitro and in vivo. (1975) (52)
Synthesis of 3'-deoxykanamycin effective against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa. (1971) (52)
The structure of a glyoxalase I inhibitor and its chemical reactivity with SH-compounds. (1975) (52)
Isolation and characterization of plasmid DNAs in Actinomycetes. (1980) (51)
New anthracycline antibiotic aclacinomycin A: experimental studies and correlations with clinical trials. (1981) (51)
Activation of DNA metabolism in T-cells by bestatin. (1979) (51)
Biological Sciences: Adrenal Tyrosine Hydroxylase and Dopamine β-Hydroxylase in Spontaneously Hypertensive Rats (1971) (50)
Isolation and properties of valanimycin, a new azoxy antibiotic. (1986) (50)
Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. (1983) (50)
Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activity. (1986) (50)
Baumycins, new antitumor antibiotics related to daunomycin. (1977) (49)
A new antibiotic, calvatic acid. (1975) (48)
A new antitumor antibiotic, bactobolin produced by Pseudomonas. (1979) (48)
KANAMYCIN: ITS DISCOVERY (1958) (48)
Marinactan, antitumor polysaccharide produced by marine bacteria. (1983) (48)
An enzyme inhibitor, panosialin, produced by Streptomyces. II. Chemistry of panosialin, 5-alkylbenzene-1,3-disulfates. (1971) (47)
Effect of bestatin on syngeneic tumors in mice. (1984) (47)
KD16-U1, a new metabolite of Streptomyces: isolation and structural studies. (1974) (47)
Small molecular immunomodifiers of microbial origin : fundamental and clinical studies of bestatin (1981) (47)
The distribution of 3H-bleomycin in mouse tissue. (1968) (46)
A NEW ANTIBIOTIC, FORMYCIN. (1964) (46)
Chemical studies on bleomycins. I. The acid hydrolysis products of bleomycin A2. (1968) (45)
Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus. (1968) (44)
Structures of pluramycin A and neopluramycin. (1977) (44)
Antitumor activity of erbstatin, a tyrosine protein kinase inhibitor. (1987) (44)
Total synthesis of bleomycin A21) (1982) (44)
Blastogenic responses and the release of interleukins 1 and 2 by spleen cells obtained from rat skin allograft recipients administered with 15-deoxyspergualin. (1987) (44)
Biological studies on the degradation products of 3-[(S)-1'-phenylethylamino]propylaminobleomycin: a novel analog (pepleomycin). (1979) (43)
The chemical synthesis of bestatin. (1976) (43)
DNA-bleomycin interaction: Nucleotide sequence-specific binding and cleavage of DNA by bleomycin (1984) (42)
Isolation of isoflavones inhibiting DOPA decarboxylase from fungi and streptomyces. (1975) (42)
A new microbial metabolite phosphoramidon (Isolation and structure) (1972) (42)
Lipid peroxidation by bleomycin-iron complexes in vitro. (1985) (42)
Enhancement of interleukin 1 and interleukin 2 releases by ubenimex. (1987) (42)
The total synthesis of spergualin, an antitumor antibiotic. (1981) (42)
Negamycin, a miscoding antibiotic with a unique structure. (1972) (42)
Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. I. Glycosidation of various anthracyclinones by an aclacinomycin-negative mutant and biosynthesis of aclacinomycins from aklavinone. (1980) (42)
Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunorubicin-producing microorganism. (1986) (42)
Resistance mechanisms of kanamycin-, neomycin-, and streptomycin-producing streptomycetes to aminoglycoside antibiotics. (1981) (41)
Antrimycin, a new peptide antibiotic. (1981) (41)
Phosphorylation and inactivation of kanamycin by Pseudomonas aeruginosa. (1968) (41)
Studies on Aminosugars. XXXII. Synthesis of 3′, 4′-Dideoxykanamycin B (1972) (41)
Purification and properties of kanamycin-phosphorylating enzyme from Pseudomonas aeruginosa. (1969) (41)
Mechanism of kasugamycin action on polypeptide synthesis. (1966) (41)
Characterization of bleomycin action on DNA. (1975) (41)
Inhibition of tyrosine protein kinase by synthetic erbstatin analogs. (1987) (41)
Mechanism of action of phleomycin, a tumor-inhibitory antibiotic. (1963) (40)
New antibiotic-producing streptomycetes, selected by antibiotic resistance as a marker. I. New antibiotic production generated by protoplast fusion treatment between Streptomyces griseus and S. tenjimariensis. (1985) (40)
Microbial conversion of anthracyclinones to daunomycin by blocked mutants of Streptomyces coeruleorubidus. (1980) (40)
Fundamental and clinical studies on new bleomycin analogs. (1978) (40)
Biosynthetic studies of terpentecin. (1986) (40)
Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes. (1982) (39)
Studies on the mode of action of althiomycin. (1970) (39)
New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4. (1981) (39)
Ebelactone, an inhibitor of esterase, produced by actinomycetes. (1980) (38)
Effects of bleomycin A2 on deoxyribonuclease, DNA polymerase and ligase reactions. (1971) (38)
Decilorubicin, a new anthracycline antibiotic. (1983) (38)
Oxanosine, a novel nucleoside from actinomycetes. (1981) (38)
Macromomycin, an inhibitor of the membrane function of tumor cells. (1972) (37)
The molecular and crystal structure determination of bisanhydroalthiomycin by the x-ray diffraction method. (1974) (37)
Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes. (1970) (37)
Aminoglycoside 3'-phosphotransferases I and II in Pseudomonas aeruginosa. (1975) (37)
Kasugamycin, a new antibiotic. (1965) (37)
X-ray structure determination of (2S, 3R)-3-amino-2-hydroxy-4-phenylbutanoic acid, a new amino acid component of bestatin. (1976) (37)
Structural basis of kanamycin for miscoding activity. (1967) (37)
MICROBIAL CONVERSION OF ε-PYRROMYCINONE AND ε-ISORHODOMYCINONE TO 1-HYDROXY-13-DIHYDRODAUNOMYCIN AND N-FORMYL-1-HYDROXY-13-DIHYDRODAUNOMYCIN AND THEIR BIOACTIVITIES (1980) (36)
Ribosomal resistance of an istamycin producer, Streptomyces tenjimariensis, to aminoglycoside antibiotics. (1981) (36)
Studies on effects of forphenicinol on immune responses. (1982) (36)
New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins. (1987) (36)
Genetics and biochemical studies of chloramphenicol-nonproducing mutants of Streptomyces venezuelae carrying plasmid. (1979) (36)
The structure of baumycins A1, A2, B1, B2, C1 and C2. (1977) (36)
SYNTHESES OF (S)-4-AMINO-2-HYDROXYBUTYRYL DERIVATIVES OF 3', 4'-DIDEOXYKANAMYCIN B AND THEIR ANTIBACTERIAL ACTIVITIES (1973) (35)
Inhibition of tyrosine hydroxylase by aquayamycin. (1968) (35)
Effects of hydrolase inhibitors on fertilization of sea urchins: I. Protease inhibitors (1979) (35)
Effect of diketocoriolin B on antibody formation. (1972) (34)
Diketocoriolin B, an active derivative of coriolin B produced by Coriolus consors. (1971) (34)
Biological studies on kanamycin. (1957) (34)
Chemistry of bleomycin. XVI epi-bleomycin. (1976) (33)
Syntheses of 6'-N-methyl-kanamycin and 3',4'-dideoxy-6'-N-methylkanamycin B active against resistant strains having 6'-N-acetylating enzymes. (1972) (33)
Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes. (1985) (33)
A new antibiotic, pyridomycin. (1953) (33)
Biosyntheses of new bleomycins. (1974) (33)
Biological properties of new acyl derivatives of tylosin. (1980) (33)
SYNTHESIS OF 3'-DEOXYKANAMYCIN B (1973) (33)
The structure of SS-228Y, an antibiotic from Chainia Sp. (1975) (33)
Synthesis and antitumor activity of spergualin analogues. III. Novel method for synthesis of optically active 15-deoxyspergualin and 15-deoxy-11-O-methylspergualin. (1987) (33)
Mechanism of action of diketocoriolin B. (1973) (33)
Structure-activity relationships of anthracyclines relative to cytotoxicity and effects on macromolecular synthesis in L1210 leukemia cells. (1981) (32)
Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by snythetic polynucleotide. (1970) (32)
The structure of antrimycin. (1981) (32)
Isolation and characterization of lividomycin A inactivated by Pseudomonas aeruginosa and Escherichia coli carrying R factor. (1972) (32)
Letter: Absolute configuration of coriolin, a sesquiterpene antibiotic from Coriolus consors. (1974) (32)
Chemical studies on kasugamycin. V. The structure of kasugamycin. (1966) (32)
Kinetics of the reaction of bleomycin-Fe(II)-O2 complex with DNA. (1980) (32)
CHEMISTRY OF BLEOMYGIN. III THE SUGAR MOIETIES OF BLEOMYGIN A2 (1969) (32)
The chemistry of bleomycin. II the molecular and crystal structure of a sulfur-containing chromophoric amino acid (1968) (32)
Immunosuppression induced with cell-free fluid of Ehrlich carcinoma ascites and its fractions. (1973) (32)
ANTIMICROBIAL ACTIVITY OF KASUGAMYCIN. (1965) (31)
TWO β-LACTAMASE INHIBITORS PRODUCED BY A STREPTOMYCES (1973) (31)
NEW COMPONENTS OF BLEOMYCIN (1973) (31)
Minor congeners of antrimycin: application of secondary ion mass spectrometry (SIMS) to structure determination. (1982) (31)
Studies on inactivation of kanamycin and resistances of E. coli. (1967) (30)
Synthesis of the pyrimidine moiety of bleomycin (1980) (30)
Elimination of the ability of a kanamycin-producing strain to biosynthesize deoxystreptamine moiety by acriflavine. (1977) (30)
Mechanisms of Resistance to Aminoglycoside Antibiotics (1982) (30)
Synthesis of 4-demethoxy-11-deoxy-analogs of daunomycin and adriamycin. (1980) (30)
A new antibiotic, althiomycin. (1957) (30)
Pharmacokinetics of macrolides, lincosamides and streptogramins. (1985) (30)
Synthesis of 3'.4'-dideoxyneamine active aginst kanamycin-resistant E. coli and P. aeruginosa. (1971) (30)
Influence of coformycin on the cytostatic activity of 9-beta-D-arabinofuranosyladenine and adenosine in mouse L5178y cells. (1978) (30)
Immunosuppressive activity of 15-deoxyspergualin and its effect on skin allografts in rats. (1987) (30)
Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions. (1974) (30)
Sarkomycin, an anti-tumor substance produced by streptomyces. (1953) (30)
Advances in Bleomycin Studies (1979) (30)
Mechanism of resistance to aminoglycoside antibiotics in nebramycin-producing Streptomyces tenebrarius. (1982) (30)
The bleomycins: Antitumor copper-binding antibiotics (1980) (29)
Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. (1974) (29)
MECHANISM OF ACTION OF NEGAMYCIN IN ESCHERICHIA COLI K 12 (1970) (29)
Total synthesis of deglyco-bleomycin A2 (1981) (29)
Saphenamycin, a novel antibiotic from a strain of Streptomyces. (1982) (29)
New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. I. Isolation and characterization of various blocked mutants. (1981) (29)
Inhibition of initiation of DNA-dependent RNA synthesis by an antibiotic B44p. (1968) (29)
Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation. (1980) (29)
Production of novel antibiotic, dopsisamine, by a new subspecies of Nocardiopsis mutabilis with multiple antibiotic resistance. (1986) (29)
Studies on formycin and formycin B in cells of Ehrlich carcinoma and E. coli. (1967) (29)
A new microbial product, oudenone, inhibiting tyrosine hydroxylase. (1970) (28)
Biosynthesis of leupeptin. (1978) (28)
Structure determinations of enzymatically phosphorylated products of aminoglycosidic antibiotics by proton magnetic resonance. (1971) (28)
Chemistry of bleomycin. V. Revised structure of an amine component of bleomycin A2. (1971) (28)
Revised Structure and Stereochemistry of Coriolins (1971) (28)
Inhibition of ligase reaction by bleomycin. (1971) (28)
Siastatin B, a potent neuraminidase inhibitor: the total synthesis and absolute configuration (1988) (28)
ACTIVITY OF BESTATIN: ENHANCEMENT OF IMMUNE RESPONSES AND ANTITUMOR EFFECT (1981) (28)
Antitumor activity of spergualin, a novel antitumor antibiotic. (1986) (28)
Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. II. Structure of new anthracycline antibiotics obtained by microbial glycosidation and biological activity. (1980) (27)
Synthesis of antitumor-active 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone. (1987) (27)
Glycocinnasperimicin D, a new member of glycocinnamolyspermidine antibiotic. (1985) (27)
Relationship between antibiotic resistance and antibiotic productivity in actinomycetes which produce aminoglycoside antibiotics. (1983) (27)
Binding of blasticidin S to ribosomes. (1970) (27)
A high performance liquid chromatographic method of analysis of 4'-O-tetrahydropyranyladriamycin and their metabolites in biological samples. (1983) (26)
Letter: Gentamicin acetyltransferase in Escherichia coli carrying R factor. (1973) (26)
On a new antibiotic, griseolutein, produced by streptomyces. (1950) (26)
[Preferential inhibition of the growth of Escherichia coli strains carrying episomes]. (1970) (26)
New anthracycline antibiotics, rhodirubins. (1977) (26)
Enhancement of antitumor effect of cytotoxic agents by bestatin. (1985) (26)
Synthesis of azepinomycin and its beta-D-ribofuranoside. (1987) (26)
Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. I. Taxonomy of the producing organism and isolation and biological properties of the antibiotics. (1986) (26)
Nucleotide sequence of the streptomycinphosphotransferase and amidinotransferase genes from Streptomyces griseus. (1987) (26)
Self-resistance of a Streptomyces which produces istamycins. (1981) (26)
The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B. (1971) (26)
Negamycin inhibits termination of protein synthesis directed by phage f2 RNA in vitro. (1974) (26)
New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides. (1981) (26)
THE ABSOLUTE STRUCTURE OF ORYZOXYMYCIN (1974) (26)
Biosynthesis of 2-deoxystreptamine. (1985) (26)
Transition-metal binding site of bleomycin. A remarkably efficient dioxygen-activating molecule based on bleomycin-Fe(II) complex☆ (1986) (25)
Letter: Chemistry of bleomycin. XII. Iso-bleomycin A2, product of carbamoyl group migration. (1973) (25)
An antiviral substance, abikoviromycin, produced by Streptomyces species. (1951) (25)
CHEMISTRY OF BLEOMYCIN. XI (1973) (25)
ISOLATION OF A NEW ANTIBIOTIC SUBSTANCE, AUREOTHRICIN FROM A STRAIN OF STREPOMYCES (1948) (25)
The structure of an epidermal growth factor-receptor kinase inhibitor, erbstatin. (1986) (25)
SMALL MOLECULAR WEIGHT IMMUNOMODIFIERS PRODUCED BY MICROORGANISMS: THEIR SCREENING AND DISCOVERIES, AND THE GENETICS OF MICROBIAL SECONDARY METABOLITES (1981) (25)
Isolation and Characterization of PDE-I and II, the Inhibitors of Cyclic Adenosine-3', 5'-monophosphate Phosphodiesterase (1978) (25)
Potentiation of the cytostatic effect of bleomycin on L5178y mouse lymphoma cells by pepleomycin. (1983) (25)
Studies on lignan lactone antitumor agents. II. Synthesis of N-alkylamino- and 2,6-dideoxy-2-aminoglycoside lignan variants related to podophyllotoxin. (1986) (25)
Specific inhibition of the termination process of protein synthesis by negamycin. (1976) (24)
Cytotoxicity of spergualin and amine oxidase activity in medium. (1985) (24)
New antibiotics clazamycins A and B. (1979) (24)
Induction of antitumor resistance to mouse leukemia L1210 by spergualins. (1986) (24)
Studies on Aminosugars. XXIX. The Synthesis of 3′-O-Methylkanamycin (1972) (24)
Response in macromolecular syntheses of mouse L cells to bleomycin, with special reference to cell-antibiotic interaction. (1973) (24)
New morpholino anthracyclines, MX, MX2, and MY5. (1987) (24)
Synthesis of butirosin B. (1972) (24)
Metabolism of formycin and formycin B in vitro. (1968) (24)
Chemistry of bleomycin. IV. The structure of amine component II of bleomycin A2. (1970) (24)
STUDIES ON THE PREVENTIVE EFFECT OF KASUGAMYCIN ON RICE BLAST. (1965) (24)
Cellular uptake and efflux and cytostatic activity of 4'-O-tetrahydropyranyladriamycin in adriamycin-sensitive and resistant tumor cell lines. (1984) (24)
Biosynthesis of daunomycinone from aklavinone and epsilon-rhodomycinone. (1980) (24)
R Factor-Mediated Aminoglycoside Antibiotic Resistance in Pseudomonas aeruginosa: a New Aminoglycoside 6′-N-Acetyltransferase (1975) (24)
Antitumor effect of forphenicinol, a low molecular weight immunomodifier, on murine transplantable tumors and microbial infections. (1982) (24)
Enzymatic conversion of aclacinomycin A to Y by a specific oxidoreductase in Streptomyces. (1979) (24)
Isolation and characterization of bottromycins A2, B2, C2. (1967) (24)
The structure of althiomycin. (1974) (24)
The crystal and molecular structures of oxoformycin B and formycin, B (1976) (24)
Transition-metal binding site of bleomycin. A synthetic analogue equivalent to bleomycin in activating molecular oxygen (1986) (24)
Letter: Chemical cleavage of bleomycin to bleomycinic acid and synthesis of new bleomycins. (1973) (24)
Synthesis of forphenicinol and forphenicine. (1982) (23)
The crystal structure of kanamycin. (1968) (23)
The X-ray structure determination of oxanosine. (1981) (23)
Studies on Aminosugars. XXX. The Synthesis of 3′-Deoxykanamycin (1972) (23)
Suppression of humoral immunity in dogs by 15-deoxyspergualin. (1987) (23)
New anthracycline antibiotic, 2-hydroxyaclacinomycin A. (1981) (23)
PREPARATION OF BLEOMYGINIG ACID: HYDROLYSIS OF BLEOMFYGIN B2 BY A FUSARIUM AGYLAGMATINE AMIDOHYDROLASE (1973) (23)
Chemistry of bleomycin. XVII. Chemical proof for the beta-lactam of bleomycin. (1977) (23)
Biochemical studies on bactobolin in relation to actinobolin. (1981) (23)
INHIBITION OF DOPAMINE β-HYDROXYLASE BY AQUAYAMYCIN (1968) (23)
6'-N-acetylation of 3',4'-dideoxykanamycin B by an enzyme in a resistant strain of Pseudomonas aeruginosa. (1972) (23)
Screening of small molecular microbial products modulating immune responses and bestatin. (1980) (23)
SEPARATION OF PHLEOMYCIN COMPONENTS AND THEIR PROPERTIES. (1964) (22)
A new microbial metabolite, sphydrofuran. I. Isolation and the structure of a hydrolysis product. (1971) (22)
Reticulol, an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase. (1975) (22)
Effects of several tumor-inhibitory antibiotics on immunological responses. (1969) (22)
Studies on kanamycin. (1957) (22)
New anthracyclinone metabolites from two blocked mutants of Streptomyces galilaeus MA144-M1. (1982) (22)
Bleomycin inhibition of DNA synthesis in isolated enzyme systems and in intact cell systems. (1975) (22)
Liblomycin, a new analogue of bleomycin. (1987) (22)
Inhibition of RNA and DNA polymerase reactions by pluramycin A. (1965) (22)
New anthracyclic antibiotics roseorubicins A and B. (1979) (22)
S-2,3-dicarboxy-aziridine, a new metabolite from a Streptomyces. (1975) (22)
Biosynthesis of aklavinone and aclacinomycins. (1981) (22)
Oudenone, a novel tyrosine hydroxylase inhibitor from microbial origin. (1971) (22)
Synthetic studies on pyrrolizidine alkaloid antitumor agents. Enantioselective synthesis of retronecine and its enantiomer from D-glucose (1985) (22)
Enhancement of immune responses and possible inhibition of suppressor cells by aclacinomycin A. (1981) (22)
CHEMICAL STUDIES ON BLEOMYCINS. I (1968) (22)
Natural and artificial bleomycins: chemistry and antitumor activities. (1971) (21)
A new antibiotic, phleomycin. (1956) (21)
The chemistry of bleomycin. 8. The structure of the sugar moiety of bleomycin A 2 . (1972) (21)
Aminoglycoside 3'-phosphotransferase III, a new phosphotransferase. Resistance mechanism. (1975) (21)
Stereoselective synthesis of (2s,3s,4r)-4-amino-3-hydroxy-2-methyl-pentanoic acid, an amino acid constituent of bleomycin, by aldold condensation)☆ (1982) (21)
The structure of a new antibiotic, terpentecin. (1985) (21)
Formycin B and its relation to formycin. (1965) (21)
Prolongation of rat heart allograft survival by 15-deoxyspergualin. (1987) (21)
MINOSAMINOMYCIN, A NEW ANTIBIOTIC CONTAINING MYO-INOSAMINE (1974) (21)
New antibiotics, ilamycins. (1962) (21)
Recent advances in chemistry and biochemistry of antibiotics (1964) (21)
Isolation, characterization and structural elucidation of new amino acids from bottromycin A. (1965) (21)
The total synthesis of kasugamycin. (1972) (21)
Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes. (1984) (21)
Structure and Chemical Synthesis of Amastatin (1979) (21)
Syntheses of 23-dialkylamino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide effective against gram-negative bacteria. (1982) (21)
SYNTHESES AND ANTITUMOR ACTIVITIES OF 7-O-(2, 6-DIDEOXY-2-FLUORO-α-L-TALOPYRANOSYL)-DAUNOMYCINONE AND -ADRIAMYCINONE (1986) (20)
Antitumor activity of new morpholino anthracyclines. (1988) (20)
Ribocitrin, a new inhibitor of dextransucrase. (1981) (20)
Studies on Aminosugars. XXXV. Syntheses of 3′,4′-Dideoxyneamine and 3′- and 4′-O-Methylneamines (1973) (20)
Decilonitrose and 4-O-succinyl-L-diginose, sugar components of decilorubicin. (1983) (20)
Transition-metal binding site of bleomycin. A synthetic analogue capable of binding Fe(II) to yield an oxygen-sensitive complex (1981) (20)
Transfer of the leupeptin-producing ability of the strain, Streptomyces roseus MA839-A1, by conjugation. (1978) (20)
Antitumor effect of bactobolin and its influence on mouse immune system and hematopoietic cells. (1980) (20)
Structure of pyridindolol, inhibitor of beta-galactosidase. (1975) (20)
Mode of action of oxanosine, a novel nucleoside antibiotic. (1982) (20)
The revised structure of bottromycin A2. (1976) (20)
Inhibition of polypeptide synthesis by kasugamycin, an aminoglycosidic antibiotic. (1966) (20)
The Structure of MS-3: A Glyoxalase I Inhibitor Produced by a Mushroom (1975) (20)
An evaluation of taxonomic criteria in streptomycetes on the basis of deoxyribonucleic acid homology. (1972) (20)
New antibiotic-producing streptomycetes, selected by antibiotic resistance as a marker. II. Features of a new antibiotic-producing clone obtained after fusion treatment. (1985) (20)
Immunochemical identification of the cell surface bound leucine aminopeptidase, the target enzyme for the immunostimulant bestatin. (1983) (20)
CHEMISTRY OF BLEOMYCIN. XII (1973) (20)
Synthesis and antitumor activity of spergualin analogues. II. Chemical modification of the spermidine moiety. (1987) (20)
Trisarubicinol, new antitumor anthracycline antibiotic. (1981) (20)
The structure of decilorubicin. (1984) (20)
Multiple resistance to aminoglycoside antibiotics in actinomycetes. (1983) (20)
Immunomodulating properties of bestatin in cancer patients. A phase II trial. (1986) (19)
Synthetic study towards man-designed bleomycins. Synthesis of a DNA cleaving molecule based on bleomycin (1986) (19)
The effect of ubenimex on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumor in rats. (1986) (19)
Structure of minosaminomycin. (1975) (19)
Chemistry of bleomycin. XXIV. Deadmido bleomycin from viewpoint of metal coordination and oxygen activation. (1979) (19)
A new anthracycline metabolite D788-1 (10-carboxy-13-deoxocarminomycin) in daunorubicin beer. (1986) (19)
Synthesis of 4'-deoxymycaminosyl tylonolide. (1981) (19)
Action of ubenimex on aminopeptidase activities in spleen cells and peritoneal macrophages from mice. (1987) (19)
A synthesis of 3',4'-dideoxykanamycin B. (1976) (19)
Isolation and characterization of a new antibiotic, dioxapyrrolomycin, related to pyrrolomycins. (1987) (19)
Effect of 15-deoxyspergualin on graft-v-host disease in mice. (1987) (19)
Leupeptin and antipain. Strong competitive inhibitors of sperm acrosomal proteinase (boar acrosin) and kallikreins from porcine organs (pancreas, submand. glands, urine). (1973) (19)
The crystal structure of formycin hydrobromide monohydrate (1974) (19)
Different Sensitivity to Bleomycin-Induced Pulmonary Fibrosis among Various Strains of Mice (1987) (19)
Antitumor anthracycline antibiotics, aclacinomycin A and analogues. I. Taxonomy, production, isolation and physicochemical properties. (1979) (19)
Mazethramycin, a new member of anthramycin group antibiotics. (1980) (18)
Studies on the biosynthesis of 3-amino-3-deoxy-D-glucose. (1968) (18)
Chemistry of enzyme inhibitors of microbial origin (1973) (18)
Distribution of chloramphenicol acetyltransferase and chloramphenicol-3-acetate esterase among Streptomyces and Corynebacterium. (1977) (18)
The total synthesis of kasugamycin. (1968) (18)
Microbial conversion of daunomycin, carminomycin I and feudomycin A to adriamycin. (1981) (18)
Arglecin, a new microbial metabolite isolation and chemical structure. (1971) (18)
Synthesis of 2′,3′-Dideoxy-2′-Fluorokanamycin A (1985) (18)
Studies on antibiotic actinomycetes. IX. On Streptomyces producing a new antifungal substance mediocidin and antifungal substances of fungicidin-rimocidin-chromin group, eurocidin group and trichomycin-ascosin-candicidin group. (1954) (18)
Synthesis of lividomycin A 5''-phosphate, an enzymatically inactivated lividomycin A. (1972) (18)
Syntheses of 3-fluoro derivatives of sporaricin A, 3-epifluoro-, 3-fluoror, and 3,3-difluoro-3-demethoxysporaricin A. (1982) (18)
SYNTHESIS OF 4-AMINO-3 HYDROXY-6-METHYLHEPTANOIG ACID, AN AMINE COMPONENT OF PEPSTATIN (1973) (18)
Synthesis of 3',4'-dideoxy and 3',4',5''-trideoxyribostamycin active against kanamycin-resistant E. coli and P. aeruginosa. (1972) (18)
New anthracycline derivatives from betaclamycin A. (1984) (18)
Reductive cleavage of anthracycline glycosides by microsomal NADPH-cytochrome C reductase. (1977) (18)
Structure-activity relationships among negamycin analogs. (1976) (18)
Blastmycin, a new antibiotic from Streptomyces sp. (1957) (18)
CLASSIFICATION OF ANTIBIOTIC STRAINS OF STREPTOMYCES AND THEIR ANTIBIOTIC SUBSTANCES ON THE BASIS OF THEIR ANTIBACTERIAL SPECTRA (1948) (17)
Letter: X-ray structure determination of 4-amino-3-hydroxy-6-methylheptanoic acid, an amine component of pepstatin. (1973) (17)
Variotin, a new antifungal antibiotic, produced by Paecilomyces varioti Bainier var. antibioticus. (1959) (17)
A -lactamase of Escherichia coli. (1972) (17)
Chemistry of bleomycin. VI. Selective cleavage of bleomycin A 2 by N-bromosuccinimide. (1972) (17)
Studies on the reconstitution of macromomycin a d auromomycin from the chromophore and protein moieties. (1982) (17)
Recent studies on bleomycin. (1977) (17)
Dopastin, an inhibitor of dopamine -hydroxylase. (1972) (17)
Application of high-voltage paper electrophoresis for separation and identification of antibiotics. (1969) (17)
PHARMACOLOGY OF KASUGAMYCIN AND THE EFFECT ON PSEUDOMONAS INFECTION. (1965) (17)
Synthesis of cleonine, amino(1-hydroxycyclopropyl)acetic acid, a novel amino acid contained in cleomycin (1980) (17)
Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60. (1986) (17)
The antiproliferative action of deoxyspergualin is different from that induced by amine oxidase. (1988) (17)
Regio- and stereo-specific synthesis of threo-3-amino-2-hydroxy-acids, novel amino-acids contained in aminopeptidase inhibitors of microbial origin. (1980) (17)
Studies on antitumor activity, antimicrobial activity and toxicity of phleomycin. (1966) (17)
A degradation product of the chromophore of auromomycin. (1983) (17)
New antitumor antibiotics, ditrisarubicins A, B and C. (1983) (17)
Inactivation of 3',4'-dideoxykanamycin B by an enzyme solution of resistant E. coli and isolation of 3',4'-dideoxykanamycin B 2''-guanylate and 2''-inosinate. (1972) (17)
Biosynthesis of leupeptin. II Purification and properties of leupeptin acid synthetase. (1979) (17)
Production of tertiomycin (a new antibiotic substance), azomycin and eurocidin by S. eurocidicus. (1955) (17)
Basidalin, a new antibiotic from basidiomycetes. (1983) (17)
Transformation of formycin to formycin B and their biological activities. (1965) (17)
Antitumor activities of (2"R)-4'-O-tetrahydropyranyl-adriamycin (THP) and its combination with other antitumor agents on murine tumors. (1985) (17)
Mechanism of action of kasugamycin. (1965) (16)
Synthesis of 3'-deoxy-3'-fluorokanamycins A and B active against resistant bacteria. (1985) (16)
Dotriacolide, a new beta-lactamase inhibitor. (1981) (16)
Small molecular microbial products enhancing immune response. (1978) (16)
Enhancement of graft-versus-host reaction and delayed cutaneous hypersensitivity in mice by ubenimex. (1986) (16)
Sarkomycin, and anti-cancer substance produced by Stroptomyces. (1954) (16)
Physical characterization of plasmids from Streptomyces kasugaensis MB273. (1981) (16)
SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONS OF BESTATIN ANALOGS, INHIBITORS OF AMINOPEPTIDASE B (1977) (16)
Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. (1981) (16)
DNA strand scission of methanol-extracted chromophores of macromomycin and auromomycin. (1982) (16)
New macrolide antibiotics produced by mutants from Streptomyces fradiae NRRL 2702. (1982) (16)
Adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats. (1971) (16)
SYNTHESIS OF 3'', 4''-DIDEOXYBUTIROSIN B (1973) (16)
Biosynthesis of the formycin family. (1971) (16)
Synthesis of 3′-Deoxykanamycin B (Tobramycin) (1976) (16)
Combimicins, new kanamycin derivatives bioconverted by some Micromonosporas. (1981) (16)
Biosynthesis of leupeptin. III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine. (1980) (16)
Studies of tylosin derivatives effective against macrolide-resistant strains: synthesis and structure-activity relationships. (1982) (16)
Isolation of paromamine inactivated by Pseudomonas aeruginosa. (1968) (16)
Effective synthesis of erbstatin and its analogs. (1987) (16)
Mode of action of enomycin, an antitumor antibiotic of high molecular weight. I. Inhibition of protein synthesis. (1967) (16)
On a new antifungal substance, mediocidin, and other antifungal substances of Streptomyces with three characteristic absorption maxima. (1954) (15)
Purification of aminoglycoside 3'-phosphotransferase II. (1976) (15)
Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. (1972) (15)
An improved total synthesis of bleomycin. (1983) (15)
D-beta-lysylmethanediamine, a new biogenetic amine produced by a Streptomyces. (1986) (15)
Macarbomycin, an inhibitor of peptidoglycan synthesis. (1972) (15)
Syntheses and properties of the 6"-deoxy or 4",6"-dideoxy derivatives of the kanamycin antibiotics. (1980) (15)
Synthesis and antitumor activities of 14-O-acyl derivatives of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)adriamycinone. (1988) (15)
STREPTOVARICIN- AND RIFAMPIGIN-RESISTANGE OF RNA POLYMERASE IN A RESISTANT CLONE OF ESCHERICHIA COLI B (1968) (15)
Structure studies on kanamycin. (1958) (15)
Chemistry of bleomycin. VII. Synthesis of -amino- -(4-amino-6-carboxy-5-methylpyrimidin-2-yl)-propionic acid, an amine component of bleomycin. (1972) (15)
Increased sensitivity to oxanosine, a novel nucleoside antibiotic, of rat kidney cells upon expression of the integrated viral src gene. (1985) (15)
Specificity of transport of bleomycin and cobalt-bleomycin in L5178Y cells. (1982) (15)
3-epi-deoxynegamycin and leucyl-3-epi-deoxynegamycin produced by Streptomyces. (1977) (15)
8''-Hydroxypactamycin and 7-deoxypactamycin, new members of the pactamycin group. (1986) (15)
Cylinder plate method of testing the anti-cell effect; studies on antitumor substances produced by Actinomycetes. XII. (1956) (15)
Relationship between enhancement of morphine analgesia and inhibition of enkephalinase by 2S, 3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives. (1982) (15)
SYNTHESIS OF 3'-DEOXYRIBOSTAMYCIN (1973) (15)
The biosynthesis of pyridomycin. I. (1968) (15)
Bottromycin A1, A2 and their structures. (1966) (15)
Synthesis of 3'-deoxybutirosin B. (1975) (15)
Aminoglycoside 6'-N-acetyl-transferase of Pseudomonas aeruginosa: structural requirements of substrate. (1975) (15)
REVISED STRUCTURE FOR ARGLEGIN (1972) (14)
Chemistry of bleomycin. XXVII. Cleomycin, a new family of bleomycin-phleomycin group. (1980) (14)
Synthesis of a Lividomycin B Analogue, 5-O-[3-O-(2-Amino-2-deoxy-α-D-grlucopyranosyl)-β-D-ribofuranosyl]-3′-deoxyparomamine (1977) (14)
Studies of the mechanism of action of diketocoriolin B to enhance antibody formation. (1981) (14)
A tryptophan hydroxylase inhibitor produced by a streptomycete: 2,5-dihydro-L-phenylalanine. (1977) (14)
Syntheses of corliolin, 1-deoxy-1-ketocoriolin and 1,8-dideoxy-1,8-diketocoriolin from coriolin B. (1980) (14)
Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. (1981) (14)
Factors Affecting Infection of Protoplasts with Deoxyribonucleic Acid of Actinophage PK-66 (1968) (14)
Studies on lignan lactone antitumor agents. I. Synthesis of aminoglycosidic lignan variants related to podophyllotoxin. (1986) (14)
PHENOMYCIN, TOXIGITY AND DISTRIBUTION (1971) (14)
Bacillus cereus beta-lactamase. Reaction with N-bromosuccinimide and the properties of the product. (1975) (14)
Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)-3',4'-dideoxyneamine. (1973) (14)
Reaction of bleomycin with DNA. Strand scission of DNA in the absence of sulfhydryl or peroxide compounds. (1971) (14)
A new antitumor substance, pluramycin; studies on antitumor substances produced by Actinomycetes. XI. (1956) (14)
Synthesis of 3'-deoxy-3'-fluorokanamycin A and 3',4'-dideoxy-3'-fluorokanamycin A. (1991) (14)
Studies on biosynthesis of kasugamycin. V. Biosynthesis of the amidine group. (1968) (14)
Synthetic studies on an antitumor antibiotic, bleomycin. XIV. The synthesis of Boc-pyrimidoblamic acid. (1985) (14)
Current status of Japanese studies with the new anthracycline antibiotic aclacinomycin A. (1980) (14)
The structure of kasugamycin hydrobromide by x-ray crystallographic analysis. (1966) (14)
Chapter 23 – NEW ANALOGS AND DERIVATIVES OF BLEOMYCIN (1985) (14)
Biochemical activities of the derivatives of dehydrodicaffeic acid dilactone. (1978) (14)
New potent anthracyclines, barminomycins I and II. (1988) (14)
Pharmacological action of FD-008, a new dopamine beta-hydroxylase inhibitor. I. Effects on blood pressure in rats and dogs. (1975) (14)
Structure of a neothramycin-2'-deoxyguanosine adduct. (1981) (14)
Studies on enomycin, a new antitumor substance (1963) (14)
HYDROXYPEPSTATIN, A NEW PEPSTATIN PRODUCED BY STREPTOMYCES (1973) (14)
In situ inhibition of tyrosine protein kinase by erbstatin. (1987) (14)
Protease inhibitors produced by microorganisms. (1977) (14)
CHEMISTRY OF BLEOMYGIN. IV (1970) (14)
A facile total synthesis of oxanosine, a novel nucleoside antibiotic (1983) (14)
Isolation and structures of istamycin components (1982) (14)
Monazomycin, a new antibiotic produced by a Streptomyces. (1963) (14)
Activity of ribosomes from kanamycin-resistant E. coli. (1964) (14)
The structure of arphamenines A and B. (1983) (14)
Chemical modification of 5,3',4'-trideoxykanamycin B. (1981) (13)
CHEMISTRY OF BLEOMYCIN. VII (1972) (13)
Synthesis of Butirosin B and Its 3′,4′-Dideoxy Derivative (1974) (13)
Vanoxonin, a new inhibitor of thymidylate synthetase. (1983) (13)
New anthracycline antibiotics obtained by microbial glycosidation of beta-isorhodomycinone and alpha 2-rhodomycinone. (1984) (13)
The structure of bottromycin A2, a new component of bottromycins. (1966) (13)
Studies on anti-tumor substances produced by microorganisms. III. On sarkomycin produced by a strain resembling to Streptomyces erythrochromogenes. (1953) (13)
Studies on Aminosugars. XXXVI. Syntheses of 3′,4′-Dideoxy-and 3′,4′,5″-Trideoxyribostamycin (1973) (13)
Kinetic studies on the inhibition of (Na+++K+)-ATPase by diketocoriolin B. (1973) (13)
Inhibition of protein synthesis by bottromycin A2 and its hydrazide. (1966) (13)
Immunological studies of aminoglycoside 3'-phosphotransferases. (1976) (13)
The chemistry of pyridomycin. (1968) (13)
Experimental studies on aclacinomycin. (1985) (13)
Further studies on the effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine. (1977) (13)
The activity of 4''-acylated tylosin derivatives against macrolide-resistant gram-positive bacteria. (1979) (13)
Suppression of experimental allergic encephalomyelitis in guinea pigs by spergualin and 15-deoxyspergualin. (1987) (13)
Inhibition by kasugamycin of protein synthesis in Piricularia oryzae. (1968) (13)
7 – Low-molecular-weight Enzyme Inhibitors and Immunomodifiers (1988) (13)
3'-Deoxyamikacin and 3',4'-dideoxyamikacin and their antibacterial activities. (1979) (13)
Localization of kanamycin sensitivity in the 23S core of 30S ribosomes of E. coli. (1968) (13)
Syntheses of 2',3'-dideoxykanamycin A, 2',3'-dideoxyamikacin and related substances (1987) (12)
The structure of spinamycin. (1968) (12)
Studies on aminoglycoside antibiotics: enzymic mechanism of resistance and genetics. (1979) (12)
Studies on biosynthesis of kasugamycin. 3. Biosynthesis of the d-inositol moiety. (1968) (12)
Synthesis of isocoformycin, an adenosine deaminase inhibitor of synthetic origin. (1979) (12)
Letter: Syntheses of isoseryl derivatives of kanamycins and their antibacterial activities. (1974) (12)
2"-N-formimidoylistamycin A and B produced by Streptomyces tenjimariensis. (1982) (12)
Reversible binding of macromomycin, a macromolecular eptide antibiotic, to cell membranes. (1971) (12)
Electrochemical and ESR studies on Cu(II) complexes of bleomycin and its related compounds. (1981) (12)
Structure of griseolutein A. (1959) (12)
Studies on biosynthesis of kasugamycin. I. Biosynthesis of kasugamycin and the kasugamine moiety. (1968) (12)
SYNERGISM OF D-4-AMINO-3-ISOXAZOLIDONE AND O-CARBAMYL-D-SERINE. (1964) (12)
The generation of additional antibiotic resistance by protoplast regeneration of a Streptomyces griseus strain. (1985) (12)
LEUCYLNEGAMYCIN, AN ANTIBIOTIC FROM NEGAMYCIN-PRODUCING STREPTOMYCES (1971) (12)
Synthesis of (14R)- and (14S)-14-De(hydroxymethyl)-14-hydroxymycaminosyl Tylonolides (1987) (12)
Synthesis and Structure-activity Relationships of Amastatin Analogues, Inhibitors of Aminopeptidase A (1982) (12)
Studies on mikamycin B. (1959) (12)
Studies on dienomycins. II. Chemical structures of dienomycins A, B and C. (1970) (12)
Antitumor cells found in tumor-bearing mice given ubenimex. (1987) (12)
3'-deamino-3'-morpholino derivatives of daunomycin, adriamycin and carminomycin. (1982) (12)
Affinity labeling of an Escherichia coli β-lactamase (1973) (12)
ISOLATION AND CHARACTERIZATION OF BOTTROMYCINS A AND B. (1965) (11)
Inhibition of nucleic acid biosynthesis in cell-free systems of Escherichia coli B by pluramycin. (1970) (11)
Effect of spergualin in autoimmune disease mice. (1987) (11)
Effects of spergualin and 15-deoxyspergualin on the development of graft-versus-host disease in mice. (1987) (11)
DNA structures required for bleomycin binding. (1978) (11)
Effect of desdanine on nucleoside diphosphate kinase and pyruvate kinase of Escherichia coli. (1975) (11)
Total synthesis of the disaccharide of bleomycin, 2-0-(α-D-mannopyranosyl)-L-gulopyranose (1981) (11)
A new synthesis of deglyco-bleomycin A2 aiming at the total synthesis of bleomycin (1982) (11)
Antiviral effect of formycin derivatives. (1967) (11)
BIOSYNTHESIS OF KASUGAMYCIN. II (1968) (11)
Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus. (1981) (11)
A new destomycin-family antibiotic produced by Saccharopolyspora hirsuta. (1985) (11)
Inhibition of dopamine beta-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo. (1970) (11)
Relationship Between Sex-Pili Formation and Macarbomycin Sensitivity in Escherichia coli (1971) (11)
Studies on new aminoglycoside antibiotics, istamycins, from an actinomycete isolated from a marine environment. II. Possible involvement of plasmid in istamycin production. (1980) (11)
Antitumor effect of a new antibiotic, neothramycin. (1980) (11)
The chemical synthesis of pepstatin A. (1972) (11)
An Alternate Synthesis of Leupeptins and Their Analogs (1973) (11)
Low-molecular-weight immunomodifiers produced by micro-organisms. (1985) (11)
The crystal and molecular structure of coformycin (1976) (11)
Formycin-deaminating activity of microorganisms. (1967) (11)
Synthesis of the 3-O-demethyl and 2"-N-formimidoyl derivatives of istamycin B. (1980) (11)
Synthesis and antibacterial activity of 6'-N-alkyl derivatives of 1-N-[(S)-4-amino-2-hydroxybutyryl]-kanamycin. (1975) (11)
Biosynthesis of valanimycin. (1986) (11)
METHYLSPINAZARIN AND DIHYDROMETHYLSPINAZARIN, GATEGHOL-O-METHYL TRANSFERASE INHIBITORS PRODUCED BY STREPTOMYCES (1973) (10)
ON THE NEW SOURCE OF CHLOROMYCETIN, STREPTOMYCES OMIYAENSIS (1949) (10)
Bleomycin Antibiotics: Metal Complexes and Their Biological Action (1986) (10)
Pharmacokinetics and disposition of 4′-O-tetrahydropyranyladriamycin in mice by HPLC analysis (2004) (10)
Effect of oxygen concentration on pulmonary fibrosis caused by peplomycin in mice. (1984) (10)
3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases. (1984) (10)
SYNTHESES OF 3''- AND 4''-O-METHYLENEAMINE (1972) (10)
Synthesis of demethyl derivatives of istamycin A. (1980) (10)
An antibiotic, plurallin, consisting of a pluramycin-like prosthetic group and a glycoprotein. (1966) (10)
Chemistry of bleomycin. XXV. Reductive methylation of bleomycin, a chemical proof for the presence of the free secondary amine in bleomycin. (1980) (10)
THE STRUCTURES OF ILAMYCIN AND ILAMYCIN B2. (1964) (10)
Unamycin, an antifungal substance produced by Streptomyces fungicidicus. (1960) (10)
A novel enantiocontrolled synthesis of (+)-9-deacetyl-9-(hydroxymethyl)-4-demethoxydaunomycinone. (1987) (10)
Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1988) (10)
Biochemical studies of the hatching process in sea urchin embryos. I. Effects of protease inhibitors (1979) (10)
Synthesis of 3"-epi-dihydrostreptomycin active against resistant bacteria. (1976) (10)
ON THE STRUCTURE OF NETROPSIN. (1964) (10)
[12] Electrophoresis of antibiotics (1975) (10)
Studies on biosynthesis of kasugamycin. IV. Biosynthesis of the kasugamine moiety from [1-14C]-glucosamine and [1,2 or 6-14C]-glucose. (1968) (10)
Syntheses of All Four Possible Diastereomers of Etoposide and Its Aminoglycosidic Analogues via Optical Resolution of (±) -Podophyllotoxin by Glycosidation with D- and L-Sugars (1987) (10)
Total Syntheses of Indicine N-Oxide, Intermedine N-Oxide, and Their Enantiomers Using Carbohydrate as a Chiral Educt (1987) (10)
Studies on low molecular weight immunomodifiers, bestatin, etc. discovery and actions (1984) (10)
Further studies on inhibition of protein synthesis by fusidic and helvolinic acids. (1967) (10)
Letter: Chemistry of bleomycin. XIV. Biogenetic-like synthesis of (2S, 3S, 4R)-4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. (1974) (10)
Purification and properties of an enzyme reducing leupeptin acid to leupeptin. (1981) (10)
Identity of latumcidin with abikoviromycin. (1958) (10)
Studies on inhibition of adenosine deaminase by isocoformycin in vitro and in vivo. (1979) (10)
Inhibition of the initial dipeptide synthesis of globin chains by the antibiotic enomycin in the reticulocyte lysate. (1976) (10)
[Experimentally induced bleomycin pulmonary toxicity--comparison of the systemic (intraperitoneal) and local (intratracheal) administration]. (1983) (10)
Synthesis of 5''-deoxylividomycin B. (1972) (10)
The effect of fusidic acid on protein synthesis in a mammalian system. (1969) (9)
The Leeuwenhoek Lecture, 1982 - Studies of microbial products in rising to the challenge of curing cancer (1983) (9)
Vanoxonin, a new inhibitor of thymidylate synthetase. III. Inhibition of thymidylate synthetase by vanoxonin-vanadium complex. (1985) (9)
Chemistry of bleomycin. XXVI. Biosynthetic study using 13C-enriched precursors. (1980) (9)
Recent advances in microbial secondary metabolites: inhibitors of hydrolytic enzymes. (1979) (9)
ILOLATION AND CHARACTERIZATION OF LABILOMYCIN, A NEW ANTIBIOTIC. (1963) (9)
Bestatin, a stimulator of polysome assembly in T cell lymphoma (L 5178y). (1981) (9)
ON THE DIFFERENTIATION OF STREPTOMYCIN AND ALLIED SUBSTANCES (STREPTOTHRICIN GROUP) AND RAPID ISOLATION OF STREPTOMYCIN-PRODUCING STRAIN (1948) (9)
Studies on antitumor substances produced by microorganisms. IV. Sarkomycin-producing Streptomyces and other two Streptomyces producing the anti-tumor substance No. 289 and caryomycin. (1953) (9)
Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine. (1974) (9)
Synthesis of tetra-N-phenylalkylkanamycins and their antimicrobial activities. (1968) (9)
Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. (1984) (9)
ISOLATION OF A CRYSTALLINE ANTIBIOTIC SUBSTANCE FROM A STRAIN OF STREPTOMYCES AND ITS IDENTITY WITH CHLOROMYCETIN (1948) (9)
Mechanism of action of neothramycin. II. Interaction with DNA. (1979) (9)
Frontiers of Antibiotic Research (1987) (9)
Mitogenic potentials of bestatin, amastatin, arphamenines A and B, FK-156 and FK-565 on spleen lymphocytes. (1985) (9)
Activity of bottromycin against Mycoplasma gallisepticum. (1968) (9)
Studies on Glyoxalase Inhibitor Isolation of a New Active Agent, MS-3, from a Mushroom Culture (1975) (9)
Deglyco-bleomycin-iron complexes: implications for iron-binding site and role of the sugar portion in bleomycin antibiotics. (1981) (9)
Studies on the Biosynthesis of Kanamycins:Part I. Incorporation of 14 C-Glucose or 14 C-Glucosamine into Kanamycins and Kanamycin-Related Compounds (1968) (9)
A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristics. (1967) (9)
Studies on formycin and formycin B phosphates. (1965) (9)
Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)lividomycin A. (1973) (9)
Stimulation of kanamycin phosphotransferase synthesis in Escherichia coli by 3',5'-cyclic AMP. (1972) (9)
Studies on antibiotics and enzyme inhibitors. (1987) (9)
Chemistry of bleomycin. XXIII. Natural abundance 15N-NMR spectroscopic evidence for the structure of bleomycin. (1979) (9)
Antitumor spectrum of a new anthracycline, (2"R)-4'-O-tetrahydropyranyladriamycin, and effect on the cellular immune response in mice. (1985) (9)
Enhancement of colony formation of mouse bone marrow cells by ubenimex. (1987) (9)
Regio-specific total synthesis of (±)-2-hydroxyaklavinone (1984) (9)
Syntheses and properties of kanamycin C derivatives active against resistant bacteria. (1977) (8)
VANOXONIN, A NEW INHIBITOR OF THYMIDYLATE SYNTHETASE (1983) (8)
Studies on variotin, a new antifungal antibiotic. I. Preparations and properties of variotin. (1959) (8)
Biochemical mechanism of action of substance B-44-P. (1968) (8)
Brief Communication: Effect of Protease Inhibitors on Focus Formation by Murine Sarcoma Virus (1975) (8)
Chemical studies on a toxic product of Streptomyces thioluteus, aureothin. (1954) (8)
The structure of a novel inhibitor of dextransucrase (1981) (8)
Biochemical Mechanism of Kanamycin Resistance in Mycobacterium tuberculosis (1977) (8)
Recent advances in antitumor antibiotics. (1978) (8)
Differential sensitivity of RSVts (temperature-sensitive Rous-sarcoma virus)-infected rat kidney cells to nucleoside antibiotics at permissive and non-permissive temperatures. (1985) (8)
Syntheses of 5''-deoxylividomycin A and its amino derivative. (1972) (8)
Vanoxonin, a new inhibitor of thymidylate synthetase. II. Structure determination and total synthesis. (1985) (8)
Studies on the Biosynthesis of Kanamycins (1968) (8)
Crystal and molecular structure of clazamycin A. (1979) (8)
A NEW ANTIBIOTIC, GYGLAMIDOMYGIN (1971) (8)
The absolute structures of THP-adriamycins. (1984) (8)
Chemical modification of coriolin B. (1977) (8)
Crystal and Molecular Structures of Monomethyl Esters of PDE-I and PDE-II, New Inhibitors of Cyclic Adenosine-3', 5'-monophosphate Phosphodiesterase (1978) (8)
Synthesis of istamycin A. (1979) (8)
ANTITUMOR ACTIVITIES OF FORMYCIN AND LABILOMYCIN. (1964) (8)
A new antibiotic indisocin and N-methylindisocin. (1987) (8)
IMMOBILIZATION OF PHOSPHO-TRANSFERASES OBTAINED FROM RESISTANT BACTERIA (1974) (8)
Microbial conversion of epsilon-pyrromycinone and epsilon-isorhodomycinone to 1-hydroxy-13-dihydrodaunomcyin and N-formyl-1-hydroxy-13-dihydrodaunomycin and their bioactivities. (1980) (8)
Total synthesis of indisocin and N-methylindisocin. (1987) (8)
Chemical modification of oxanosine. I. Synthesis and biological properties of 2'-deoxyoxanosine. (1984) (8)
Radioimmunoassay of bleomycins. (1985) (8)
Isolation and synthesis of 2″-N-formimidoylistamycins A and B, new istamycin components (1982) (8)
The nature of thiol-compounds which trap cuprous ion reductively liberated from bleomycin-Cu(II) in cells. (1987) (8)
Biological studies on mikamycin. II. Laboratory investigations of mikamycin A and mikamycin B. (1959) (8)
Revistin found by screening for inhibitors of reverse transcriptase of an oncogenic virus. (1975) (8)
Heterogeneity among whorl-forming Streptomycetes determined by DNA reassociation. (1974) (8)
Studies on low-molecular-weight immunomodifiers produced by microorganisms: results of ten years' effort. (1984) (8)
Letter: Chemistry of bleomycin. XI. The structures of the terminal amines. (1973) (8)
Isolation and identification of the antifungal active substance in walnuts. (1967) (8)
Effect of forphenicinol on gamma-interferon production in mice sensitized with BCG. (1986) (8)
Studies on lignan lactone antitumor agents. IV: Synthesis of glycosidic lignan variants related to α-peltatin (1988) (8)
Syntheses and antitumor activities of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone. (1986) (8)
STUDIES ON THE STREPTOTHRICIN-GROUP-SUBSTANCES ON STREPTOTHRICIN A AND STREPTOTHRICIN B (1949) (8)
New microbial secondary metabolites under preclinical development for cancer treatment. (1978) (8)
Effects of o-phenanthroline, 2,2'-dipyridyl and neocuproine on the activities of bleomycin to inhibit DNA synthesis and growth of cultured cells. (1986) (8)
The structures of coriolin B and C. (1970) (8)
THIAZOLIDONE ANTIBIOTIC AS AN ANTIMETABOLITE TO BIOTIN (1953) (8)
CHEMISTRY OF BLEOMYCIN. XIV (1974) (8)
Cyclamidomycin (desdanine), an inhibitor of nucleoside diphosphokinase of Escherichia coli. (1972) (7)
Correlation between level of defense against active oxygen in Escherichia coli K12 and resistance to bleomycin. (1982) (7)
[Generation of superoxide anion by the reaction of bleomycin-Cu (II) with cysteine]. (1987) (7)
Synthetic approaches to new anthracyclines: 4,11-dideoxy-2-hydroxy-β-rhodomycinone and its glycosides (1984) (7)
Studies on biosynthesis of kasugamycin. VI. Some relationships between the incorporation of 14C-compounds and the production of kasugamycin. (1968) (7)
2''-N-formimidoylsporaricin A produced by Saccharopolyspora hirsuta subsp. kobensis. (1987) (7)
A new antibiotic, alboverticillin. (1958) (7)
Studies on phleomycin. (1959) (7)
Serum dopamine beta-hydroxylase activity in developing hypertensive rats. (1974) (7)
Studies on the intermediate metabolism of chloramphenicol production. II. On the carbohydrate metabolism of Streptomyces venezuelae. (1953) (7)
Syntheses of 4′-Deoxykanamycin and 4′-Deoxykanamycin B (1977) (7)
Reticulol, an Inhibitor of Cyclic Nucleotide Phosphodiesterases (1977) (7)
An oriented phase II trial of THP-adriamycin in breast carcinoma. (1986) (7)
Revised structure for arglecin. (1972) (7)
Syntheses of 6',5",6""-triamino-6',5",6""-trideoxylividomycin a and 6',5"-diamino-6',5"-dideoxylividomycin B. (1976) (7)
Dopamineβ-hydroxylase and tyrosine hydroxylase activities in spontaneously hypertensive rats after NaCl administration (1975) (7)
Studies on the Biosynthesis of Kanamycins:Part II. Incorporation of the Radioactive Degradation Products of Kanamycin A or Related Metabolities into Kanamycin A (1969) (7)
A new antitumor antibiotic: demethylstreptonigrin. (1986) (7)
Pharmacological action of FD-008, a new dopamine-beta-hydroxylase inhibitor. (1975) (7)
Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase. (1974) (7)
New anthracycline antibiotics: serirubicin and 1-hydroxyserirubicin. (1985) (7)
CHEMISTRY OF BLEOMYCIN. XIII (1974) (7)
A novel fatty acid from laspartomycin. (1970) (7)
NADH-dependent cinerulose reductase in rat liver microsomes. (1978) (7)
Therapy of experimental immunologically mediated aplastic anemia in mice by various immunosuppressive and antitumor agents. (1988) (7)
Degradation studies on kanamycin. (1958) (7)
One-pot preparation of 1-chlorovinylisocyanides from carbonyl compounds. (1987) (7)
Mode of action of enomycin, an antitumor antibiotic of high molecular weight. II. Preferential binding of enomycin to mammalian ribosomes. (1967) (7)
Pepthiomycin, a new peptide antibiotic mixture. (1968) (7)
24-hour rhythm of human plasma noradrenaline and the effect of fusaric acid, a dopamine-beta-hydroxylase inhibitor. (1980) (7)
Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by synthetic polynucleotide. (1970) (7)
Immunological involvement in pulmonary fibrosis induced by peplomycin. (1985) (7)
Cinemicrographic analysis of death in synchronously growing mouse L cells after exposure to bleomycin. (1973) (7)
Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis. (1970) (7)
RETRO-SYNTHETIC MANIPULATION OF BLEOMYCINS (1982) (7)
Syntheses of 1-N-(2-aminoethoxycarbonyl)kanamycin A and 1-N-(3-aminopropoxycarbonyl)kanamycin A. (1981) (7)
Inhibition of fumarase by S-2,3-dicarboxyaziridine. (1985) (7)
SYNTHESES OF 6''-AMINO-6''-DEOXYLIVI-DOMYCIN B AND 6''-DEOXY-6''-METHYLAMINO- AND 6''-DEOXY-6''-(2-HYDROXYETHYLAMINO)- LIVIDOMYCIN B (1973) (7)
A new toxic antibiotic, actinoleukin, produced by a streptomycete. (1954) (7)
A new streptomycin group antibiotic produced by Streptomyces sioyaensis. (1985) (7)
Synthesis of a Masked Derivative of 3′-Deoxydihydrostreptobiosamine, a Precursor for the Synthesis of 3″-Deoxydihydrostreptomycin (1977) (7)
Pharmacokinetics and disposition of (2''R)-4'-O-tetrahydropyranyladriamycin in dogs. (1986) (7)
Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives. (1982) (7)
Synthesis of 1-N-acyl derivatives of 3', 4'-dideoxy-6'-N-methyl-kanamycin B and their antibacterial activities. (1975) (7)
Total Synthesis of PDE-II (1979) (7)
FUSARIG ACID DERIVATIVES: THE EFFECT ON DOPAMINE β-HYDROXYLASE (1973) (7)
[11] Ion-exchange chromatography of aminoglycoside antibiotics (1975) (7)
CHEMISTRY OF BLEOMYCIN. XXVIII (1981) (7)
The structure of ryridomycin. (1967) (7)
Studies on anti-tumor substances produced by microorganisms. I. On the antitumor substance No. 289. (1953) (7)
Syntheses of 1-Epikanamycin A and Its 1-N-[(S)-4-Amino-2-hydroxybutyryl] Derivative (1983) (6)
INACTIVATION OF β-LACTAMASE BY SOME SITE-SPECIFIC REAGENTS (1974) (6)
Effects of a new adenosine deaminase inhibitor, isocoformycin, on toxicity, antitumor activity and tissue distribution of formycin A and 9-beta-D-arabinofuranosyladenine. (1980) (6)
STRUCTURES OF BOTTROMYCINS A AND B. (1965) (6)
Biosynthesis of kasugamycin. II. Biosynthesis of the two-carbon-side chain of kasugamycin. (1968) (6)
Isolation of alpha-aminoacyl arginines in screening of aminopeptidase B inhibitors. (1980) (6)
Syntheses of 9-substituted josamycin, 13-substituted isojosamycin and their tetrahydro derivatives. (1981) (6)
New Drugs in Cancer Chemotherapy (1981) (6)
Structure of a new isoflavone from fungi and Streptomyces inhibiting dopa decarboxylase. (1976) (6)
Strong binding of ditrisarubicin B to DNA. (1988) (6)
Involvement of cytotoxic T-lymphocytes in the antitumor activity of spergualin against L1210 cells. (1987) (6)
On tertiomycin B produced by Streptomyces eurocidicus. (1955) (6)
A predominant role of amino groups in the antibacterial action of aminoglycosides: synthesis of hexa- and heptadeoxykanamycin derivatives. (1983) (6)
Sulfhydryl modification and activation of phenylalanine hydroxylase by dinitrophenyl alkyl disulfide. (1987) (6)
Enzymes of Catecholamine Biosynthesis and Metabolism in Spontaneously Hypertensive Rats and Hypotensive Effects of the Specific Inhibitors from Microbial Origin (1972) (6)
The screening of beta-lactamase inhibitors: inhibition by fatty acids produced by bacteria. (1981) (6)
MECHANISM OF ACTION OF O-CARBAMYL-D-SERINE. (1963) (6)
Transformation of kanamycin a into 3′-deoxykanamycin A (1981) (6)
4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. (1987) (6)
RESISTANCES OF ANTIBIOTIC STRAINS OF STREPTOMYCES TO CHLOROMYCETIN AND A RAPID ISOLATION METHOD OF CHLOROMYCETIN PRODUCING STRAINS (1949) (6)
A possible role by bithiazoles of bleomycin in causing double-strand scission of DNA. (1981) (6)
Miscoding activities of biologically inactivated kanamycins. (1967) (6)
Biosynthetic Studies of Reticulol, an Isocoumarin, by 13C-NMR Spectroscopy (1977) (6)
Chemical studies on kasugamycin. 3. Structures of kasuganobiosamine and kasugamycinic acid. (1965) (6)
Binding of 3-O-acetyl-4"-O-isovaleryltylosin to ribosomes from a macrolide-resistant strain of Staphylococcus aureus. (1982) (6)
Monocyclic beta-lactam antibiotics: synthesis and antibacterial activity of 4-(substituted ethyl)-2-azetidinone-1-sulfonic acid derivatives. (1987) (6)
Structure of azomycin (2-nitro-imidazole). (1955) (6)
THE CHEMISTRY OF BLEOMYGIN. X (1973) (6)
Studies on Glycosylation of erythro-β-Hydroxy-L-histidine. A Key Step of Bleomycin Total Synthesis (1986) (6)
Promotion of antibody formation by prostaglandin (1974) (6)
Reduction of anthracycline glycoside by NADPH--cytochrome P-450 reductase. (1979) (6)
Purification of phenylalanine hydroxylase from human adult and foetal livers with a monoclonal antibody. (1985) (6)
Some evidence for interaction of D-cycloserine with DNA. (1982) (6)
5'-Hydroxy-2"-N-demethyl-dihydrostreptomycin produced by a Streptomyces. (1985) (5)
CHEMISTRY OF LABILOMYCIN. (1964) (5)
Transformation of Dihydrostreptomycin into 3″-Deoxydihydrostreptomycin (1981) (5)
Synthetic studies on an antitumor antibiotic, bleomycin. XIII. Synthesis of 2-formylpyrimidine, a key intermediate for the pyrimidine moiety of bleomycin. (1985) (5)
Localization of aminoglycoside 3'-phosphotransferase II on a cellular surface of R factor resistant Escherichia coli. (1976) (5)
Inhibitory effect of negamycin on polysomal ribosomes of Escherichia coli. (1976) (5)
Synthesis of 5″-Deoxy-5″-fluorolividomycin B (1983) (5)
Low-molecular weight immunomodulators produced by microorganisms. (1980) (5)
FURTHER STUDIES ON THE TRYPTOPHAN-PARTS OF ILAMYCINS. (1964) (5)
Synthesis and properties of the 6'-C-alkyl derivatives of 3',4'-dideoxykanamycin B. (1979) (5)
The studies on the chemical derivations of formycin and formycin B. (1966) (5)
Observation on the simultaneous production of actinoleukin and trichomycin group antibiotic by a Streptomyces. (1956) (5)
A new antibiotic, ractinomycin. (1955) (5)
Isolation and Structure of New Isocoumarins (1977) (5)
Chemical modification of anthracycline antibiotics. V. Synthesis of 2-hydroxyaclacinomycin A by chemical glycosidation. (1983) (5)
Synthesis of 6-deoxydihydrostreptomycin (1982) (5)
Neutral proteinases produced by Streptomyces cacaoi var. asoensis. (1970) (5)
Valanimycin acts on DNA in bacterial cells. (1987) (5)
Anti-leukemic activity of 15-deoxyspergualin against N-butyl-N-nitrosourea-induced autochthonous rat leukemia. (1986) (5)
Kasugamycin in pseudomonas infections of the urinary tract. (1967) (5)
TRANSITION-METAL BINDING SITE OF BLEOMYCIN. A SYNTHETIC ANALOG CAPABLE OF BINDING IRON(II) TO YIELD AN OXYGEN-SENSITIVE COMPLEX (1982) (5)
Letter: Chemistry of bleomycin. 8. The x-ray structure determination of 4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. (1974) (5)
The structure of arglecin, a new metabolite of streptomyces (1971) (5)
Studies on antibiotic actinomycetes. VII. Azomycin-producing strain resembling to Nocardia mesenterica. (1954) (5)
Effect of antibiotics on magnesium ion removal from E. coli ribosome suspensions. (1968) (5)
Plasmid variability in the istamycin producing strains of Streptomyces tenjimariensis. (1984) (5)
Cell Surface-Bound Leucine Aminopeptidase: Target of the Immunomodulator Bestatin (1986) (5)
Oxanosine, a novel nucleoside from actinomycetes. (1981) (5)
Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. II. Physico-chemical properties and structure determination. (1986) (5)
Alphostatin, an inhibitor of alkaline phosphatase of bovine liver produced by Bacillus megaterium. (1989) (5)
The studies on the degradation products of formycin and formycin B. (1966) (5)
Deamination of purine antibiotics by adenosine deaminase. (1965) (5)
A new antibiotic, 3,6-dihydroxyindoxazene. (1983) (5)
Studies on anti-tumor substances produced by microorganisms. II. On the process of large scale production and chemical characters of the antitumor substance No. 289. (1953) (5)
Derivatives of bottromycin A2 and their biological activity. (1967) (5)
Chemistry of bleomycin. XV absolute configuration of beta-amino-beta-(4-amino-6-carboxy-5-methylpyrimidin-2-yl)-propionic acid, an amine component of bleomycin. (1976) (5)
Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin (1973) (5)
Opening Lecture History and Development of Biochemical Mechanisms of Resistance to Aminoglycoside Antibiotics and their Active Derivatives (1975) (5)
Syntheses of 23-C-substituted derivatives of mycaminosyl tylonolide. (1986) (5)
A new antibiotic, spinamycin. (1966) (5)
Antitumor effect of forphenicinol, a low molecular weight immunomodifier, in combination with surgery on Meth A fibrosarcoma, Lewis lung carcinoma, and adenocarcinoma 755. (1986) (5)
Chemical modification of the ester group of diketocoriolin B. (1980) (5)
Isolation of actinomycin A from a strain of Streptomyces. (1948) (5)
Synthesis of 5-O-(4-deoxy-4-fluoro-β-D-mycaminosyl)tylonolide (1987) (5)
A new source of fradicinmycelin like antifungal antibiotic. (1959) (5)
Synthesis of 3-deazaoxanosines, C-nucleoside isosteres of oxanosine (1985) (5)
On Streptomyces cinnamonensis n. sp., the source of an antitubercular antibiotic of low toxicity. (1953) (5)
Reduction of cinerulose in aclacinomycin-A by soluble and microsomal cinerulose reductases. (1979) (5)
Met5-enkephalin-Arg6-Phe7 inhibition of noradrenaline and acetylcholine release from peripheral organs. (1984) (5)
The role of bestatin, an inhibitor of cell surface proteases, in the interaction of serum with untransformed cells in culture. (1981) (5)
Studies on Streptomyces kanamyceticus, producer of kanamycin. (1959) (5)
New Anthracycline Antibiotic CG12 Obtained by Microbial Glycosidation of α-Citromycinone (1986) (5)
NEW INHIBITORS OF MICROBIAL ORIGIN FOR DOPAMINE-β-HYDROXYLASE (1973) (5)
Studies on the mechanism of the agglutination; on the lattice theory. (1948) (4)
Role of intramuscular enzymatic changes in the development of muscular weakness in rats with experimental allergic neuritis (1984) (4)
Studies on the production of griseolutein. (1953) (4)
Interaction of bleomycin with nucleic acids as probed by ESR spectrometry of iron(II)-nitrosyl complex of bleomycin. (1981) (4)
Characterization and active fragment of phenomycin, an antitumor polypeptide antibiotic. (1969) (4)
A crystalline antibacterial substance from Penicillium leucopus and four other strains of Penicillia, and Aspergillus clavatus, and its probable identity with patulin. (1948) (4)
Inhibition of RNA polymerase of Escherichia coli by an antimicrobial substance B44P (streptovaricin). (1968) (4)
KF77-AG6, an antipain-related metabolite. (1974) (4)
Acrylamidine, an anti-fungal substance produced by a Streptomyces. (1968) (4)
Studies on the effects of actinomycin, cycloheximide, and other known antibiotics on Ehrlich carcinoma of mice. (1955) (4)
[Changes of anticancer activity and pulmonary toxicity of bleomycins in differences of administration schedules and routes in mice]. (1984) (4)
FOUR MINOR ANTIBIOTICS FROM MACARBOMYCINS (1973) (4)
Antibiotic-sensitivity of ribosomes from kanamycin-resistant E. coli. (1967) (4)
TAXONOMICAL STUDIES OF THE STREPTOMYCES PRODUCING ANTIMYCIN A-BLASTMYCIN GROUP ANTIBIOTICS (1959) (4)
Chemical derivation of antibiotics active against resistant bacteria. (1968) (4)
N-Substituted derivatives of 23-amino-4',23-dideoxymycaminosyl tylonolide. Synthesis and antibacterial activity. (1985) (4)
Fluorospectrometric studies on neothramycin and its reaction with DNA. (1981) (4)
TAXONOMICAL STUDIES ON A STREPTOMYCES STRAIN PRODUCING LABILOMYCIN. (1963) (4)
Chemistry of bleomycin. 3. The sugar moieties of bleomycin A2. (1969) (4)
Inhibition of DNA replication and membrane transport of some nutrients by clazamycin in Escherichia coli. (1984) (4)
Chemical studies on kasugamycin. II. The structure of methylkasugaminide. (1965) (4)
Neopluramycin, an inhibitor of nucleic acid synthesis. (1971) (4)
Synthesis of 1-N-(2-aminoethanesulfonyl)-kanamycins and related aminoglycoside antibiotics. (1983) (4)
Antitumor effect of pluramycin crude powder on Ehrlich carcinoma of mice. Studies on antitumor substances produced by microorganisms. X. (1956) (4)
1-(2-(3, 4, 5, 6-Tetrahydropyridyl))-1, 3-pentadiene an N-methyltransferase inhibitor produced by actinomycetes. (1974) (4)
The chemical conversion of gentamine C1a into gentamine C2 and its 6'-epimer. (1979) (4)
Studies on chronic toxicity of kanamycin. (1958) (4)
Syntheses of Bestatin and Its Analogues and their Bioactivity (1980) (4)
A new antitumor antibiotic, dioxolamycin. (1984) (4)
Synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]-3'-deoxyribostamycin (3'-deoxybutirosin B). (1976) (4)
THE STRUCTURE OF GRISEOLUTEIN B. (1964) (4)
Pluramycin complex with human serum albumin and the antitumor activity. (1966) (4)
CHEMISTRY OF BLEOMYCIN. XII: IS0 -BLEOMYCIN A 2 , A PRODUCT OF CARBAMOYL GROUP MIGRATION (1973) (4)
Microbial secondary metabolites with potential use in cancer treatment. (Plasmid involvement in biosynthesis and compounds. (1977) (4)
Synthesis of 6′-Amino-1- N -[( S )-4-Amino-2-Hydroxybutyryl]-6′-Deoxylividomycin A (1975) (4)
Biological studies on mikamycin. IV. Blood and tissue levels of tritiated mikamycins A and B. (1962) (4)
Biological studies on kanamycin-di-N- and tetra-N- methanesulfonates and fradiomycin (neomycin)-N-methanesulfonate. (1959) (4)
The screening of antitoxoplasmic substance produced by streptomycete and anti-toxoplasmic substance No. 534. (1955) (4)
An antibiotic, phthiomycin. (1953) (4)
A novel deoxyribonuclease inhibitor from Micromonospora. (1982) (4)
Structure and Synthesis of Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (4)
Biochemical method of screening of microbial products exhibiting antitumor activity. (1966) (4)
Chemical studies on kasugamycin. IV. Synthetic transformations of kasuganobiosamine to kasugamycinic acid, isokasugamycinic acid, and their amides. (1965) (4)
Isolation, racemization and absolute configuration of siderochelin A. (1982) (4)
TOTAL SYNTHESIS OF BLEOMYCIN A2 (1982) (4)
The Reaction Mechanism of Rat Liver Glyoxalase I and Its Inhibition by MS-3 (1976) (4)
Screening studies of antiviral substances produced by actinomycetes and new antiviral substances, niromycins. (1960) (4)
Effect of pluramycin A on Ehrlich carcinoma of mice; studies on antitumor substance produced by actinomycetes. XIII. (1957) (4)
Studies on streptothricin BI produced by S. fradiae. (1950) (4)
Characterization of the dehydrodicaffeic acid dilactone-forming enzyme and the enzymic and chemical synthesis of this mushroom product. (1977) (4)
Biological properties of macarbomycin, an antibiotic containing phosphorus. (1973) (4)
Suppression of humoral immunity in mice by spergualin. (1987) (4)
Negative control for the expression of streptomycin resistance gene from streptomycin-producing Streptomyces griseus. (1986) (4)
Chemical studies on kasugamycin. I. Acid degradation. (1965) (4)
Radioimmunoassay for aclacinomycin A. (1982) (4)
Biological studies on bottromycin A and its hydrazide. (1966) (4)
Screening of microbial inhibitors of mammalian ornithine decarboxylase. (1985) (4)
Effect of forphenicinol on the production of Ia-positive macrophages in mice with or without L1210 leukemia and on the growth of L1210 in immunized mice. (1986) (4)
Serum Dopamine β-Hydroxylase Activity in Developing Spontaneously Hypertensive Rats and the Effect of Salt Administration (1975) (3)
Synergistic effect of peplomycin in combination with bleomycin on L5178y mouse lymphoma cells in vivo. (1984) (3)
STUDIES ON AN ANTIBIOTIC SUBSTANCE OF S. GRISEUS, GRISEIN (1949) (3)
Inhibition of DNA synthesis by griseolutein in Escherichia coli through a possible interaction at the cell surface. (1978) (3)
STRUCTURE OF LABILOSE, A METHANOLYSIS PRODUCT OF LABILOMYCIN. (1964) (3)
The structure of coriolin, a new sesquiterpene antibiotic (1969) (3)
The Crystal and Molecular Structure of a Dibromo-derivative of MS-3: a Glyoxalase I Inhibitor Produced by a Mushroom, Stereum hirsutum (1976) (3)
Biological studies on mikamycin. (1958) (3)
Studies on actinoleukin; relation to echinomycin and levomycin. (1958) (3)
The total syntheses of (−)-indicine N-oxide and intermedine N-oxide (1986) (3)
Studies on a new antibiotic, exfoliatin, produced by a strain of Streptomyces. (1952) (3)
Studies on the mechanism of the agglutination; on the quantitative relation between the surface area of the bacteria and the binding agglutinin. (1948) (3)
Studies on antimicrobial substance B 44 P (streptovaricin) produced by a strain of actinomycetes. IV. Biochemical mechanism of action of substance B 44 P. (1968) (3)
Studies on the intermediate metabolism of chloramphenicol production. I. Changes of amino acids during fermentation and utilization of amino acids for chloramphenicol production. (1950) (3)
AMETABOLITE OF BLEOMYCIN A5 IN RABBIT URINE (1974) (3)
BIOGENESIS OF VARIOTIN:III. INCORPORATION OF 14 C-GLUTAMIC ACID INTO VARIOTIN (1962) (3)
Nitrosporin, antibiotic from Streptomyces nitrosporeus active to Gram positive bacteria. (1951) (3)
Reversal of resistance by N-acetyltyramine or N-acetyl-2-phenylethylamine in doxorubicin-resistant leukemia P388 cells. (1987) (3)
The existence of griseolutein A and B. (1954) (3)
Biochemical and Biological Studies on Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (3)
Studies on mikamycin. II. Comparative studies on mikamycin with streptogramin and the antibiotic No. 899. (1958) (3)
Syntheses of 23-C-alkylidene, and 23-N-containing derivatives of 5-O-mycaminosyltylonolide. (1987) (3)
Inhibition of R-factor transfer and phage infection by requinomycin. (1972) (3)
Inhibition of dopamine-beta-hydroxylase, A copper enzyme, by bleomycin. (1980) (3)
SELECTIVE TOXICITY OF KANAMYCIN AND STREPTOMYCIN. (1964) (3)
Protective effect of forphenicinol, a low molecular weight immunomodifier, against infection with Pseudomonas aeruginosa in mice and its mechanisms. (1987) (3)
Biosynthesis of Neothramycin (1978) (3)
Synthetic Studies on an Antitumor Antibiotic Bleomycin. A Synthetic Analogue Equivalent to Bleomycin in Activating Molecular Oxygen (1986) (3)
Production and extraction of niromycins, antiviral antibiotics. (1960) (3)
On screening of antiviral substances produced by streptomyces and on an antiviral substance achromoviromycin. (1953) (3)
PURIFICATION AND CHARACTERIZATION OF A SIALIDASE INHIBITOR (2006) (3)
Potentiation of the bleomycin, arabinofuranosylcytosine and adriamycin-caused inhibition of DNA synthesis in lymphocytes by bestatin in vitro. (1985) (3)
Purification and Properties of a Dehyrodicaffeic Acid Dilactone-forming Enzyme from a Mushroom, Inonotus sp. K-1410 (1977) (3)
Effect of forphenicinol on the production of lipopolysaccharide-induced interferon and tumor necrosis factor and on the growth of Meth A fibrosarcoma in mice. (1987) (3)
Adrenal enzymes of catecholamine biosynthesis and metabolism in spontaneously hypertensive rats (1971) (3)
ISOLATION OF STREPTOMYCIN FROM A PINK VARIANT OF S. GRISEUS (1948) (3)
Tetra-O-methyldehydrodicaffeic acid dilactones, (+) and (−) isomers (1977) (3)
A new antibiotic, 2-hydroxy-5-iminoazacyclopent-3-ene. (1979) (3)
An inhibitor of (Na+, K+)-ATPase produced by Streptomyces pseudovenezuelae MF722-02; purification and properties. (1982) (3)
New Plasmid‐Mediated Phosphorylation of Gentamicin C in Staphylococcus aureus (1978) (3)
Effect of sarkomycin on experimental animal tumors. (1955) (3)
BIOGENESIS OF VARIOTIN (1962) (3)
Studies on mikamycin. I. (1958) (3)
Lower toxic derivatives of antibiotics. I. N-methanesulfonate derivatives of kanamycin and neomycin. (1959) (3)
Inhibition of tyrosine hydroxylase, a Fe(II)-stimulated monooxygenase, by bleomycin. (1980) (3)
Dynamic Relationship between Hydrolytic Enzymes and the Immune System in Rheumatic Diseases (1987) (3)
Some chemical modifications of istamycin B. (1983) (3)
A NEW AMINO ACID FROM ILAMYCIN B1 AND THE STRUCTURE OF ILAMYCIN B1. (1964) (3)
Fundamental studies on bestatin: a small molecular microbial product enhancing immune response. (1981) (3)
A new antifungal substance of streptomycetes, seligocidin. (1954) (3)
Chemistry of variotin. (1960) (3)
THE STRUCTURAL DIFFERENCE AMONG ILAMYCIN, ILAMYCIN CL AND ILAMYCIN C2. (1965) (3)
Specific increase in thymidine transport at a permissive temperature in the rat kidney cells infected with srcts-Rous sarcoma virus. (1984) (3)
The Improvement of Productivity and Selective Production of Arphamenines by Addition of Their Biosynthetic Precursors (1984) (3)
Immunological cross-reactivities of various anthracycline antibiotics against aclacinomycin A antisera. (1982) (2)
Low molecular weight immunomodifiers produced by microorganisms. (1985) (2)
Biosynthesis of oncostatic antibiotics: artificial bleomycins. (1972) (2)
Inhibition of Cyclic Nucleotide Phosphodiesterases by Reticulol (1977) (2)
Phenomycin, toxicity and distribution. (1971) (2)
Proceedings : an international conference on trends in antibiotic research : genetics, biosyntheses, actions & new substances (1982) (2)
Activation of bleomycin-Fe(III) by bleomycin-Cu(II) and cysteine. (1987) (2)
On an antibiotic, sarcidin, produced by Streptomyces n. sp. S. achromogenes. (1953) (2)
Letter: Two beta-lactamase inhibitors produced by a streptomyces. (1973) (2)
Paper chromatographic studies on methanesulfonates of kanamycin and fradiomycin (neomycin). (1959) (2)
A new antibiotic, gougeroxymycin. (1969) (2)
Inhibition of melanoma tyrosinase by fusaric acid (1972) (2)
Studies on the potency test of tuberculin. (1948) (2)
Effects of biopolymers and magnesium on the mikamycins inhibition of polyphenylalanine synthesis and the synergistic action of mikamycins A and B. (1967) (2)
Biosynthesis of leupeptin. IV. Is protein turnover in leupeptin producer cells affected by leupeptin? (1980) (2)
ISHIZUKA STUDIES ON THE MECHANISM OF ANTITUMOR EFFECT OF BLEOMYICIN ON SQUAMOUS CELL CARCINOMA (1972) (2)
Effect of forphenicinol, a low molecular weight immunomodifier, on the growth of and the immune responses to murine lymphoma EL4. (1987) (2)
Antitumor antibiotics and low molecular weight immunomodifiers of microbial origin. (1984) (2)
Biochemical study of R-75-1, a new semi-synthetic rifamycin. (1981) (2)
The differentiation-promoting potential of a cytostatic fluoro-pyranosyl adriamycin analog (FAD 104). (1989) (2)
Bestatin Suppresses the Serum Levels of Several Hydrolytic Enzymes in a Patient with Progressive Muscular Dystrophy (1986) (2)
The 6'-amidine derivatives of amikacin and dibekacin. (1984) (2)
Chemical modification of 3'-deoxyamikacin. (1982) (2)
Alkaline hydrolysis of mikamycin A. (1959) (2)
Anti-inflammatory neutral proteinases, retikinonase I and II obtained from Streptomyces verticillatus var. zynogenes. (1970) (2)
Synthesis of 4'-O-acylanthracyclines (1988) (2)
Studies on the surface culture for the penicillin production. (1948) (2)
Identification of an antibiotic produced by S. galbus, n. sp. with streptomycin. (1959) (2)
Inhibition of human serum dopamineβ-hydroxylase after the oral administration of fusaric acid (1972) (2)
A method of screening for antibiotics producing oxygen radicals. (1982) (2)
Chapter 12 Enzyme Inhibitors Produced by Microorganisms (1989) (2)
Mode of action of enomycin, an antitumor antibiotic of high molecular weight. (1966) (2)
On screening method of antiviral substances produced by Streptomyces and on an antiviral substance, achromoviromycin. (1953) (2)
Antibiotics and Their Uses (1965) (2)
Mechanisms of R-Mediated Streptomycin Resistance in Pseudomonas Aeruginosa (1977) (2)
Correlation between serum dopamine-β-hydroxylase activity and dopamine-β-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands (1977) (2)
Recent Chemical Studies of Bioactive Microbial Products: Genetics, Active Structures, Development of Effective Agents with Potential Usefulness (1979) (2)
An neutral proteinase obtained from Streptomyces griseolus. (1970) (2)
Anti-biotin activity of thiazolidone antibiotic. (1953) (2)
MECHANISM OF ACTION OF ANGUSTMYCINS, MIKAMYCINS, AND PHLEOMYCIN. (1963) (2)
BIOSYNTHESIS OF DAUNOMYCINONE FROM AKLAVINONE AND e-RHODOMYCINONE (2006) (2)
Induction of DNA polymerase alpha and terminal deoxynucleotidyl transferase in the human lymphoblastoid cell line Molt-4 by the immunomodulator bestatin. (1984) (2)
Antitumour activity of new semi-synthetic anthracyclines containing fluorotalopyranose. (1988) (2)
Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids. (1983) (2)
Determination of impurities in aluminum metals by proton activation (1979) (2)
Recent Studies on Antibiotics and Low Molecular Weight Enzyme Inhibitors (1982) (2)
GUEST EDITORIAL – PROBLEMS AND TRENDS IN THE DEVELOPMENT OF NEW ANTIBIOTICS AND OTHER USEFUL MICROBIAL PRODUCTS (1981) (2)
BIOGENESIS OF VARIOTIN:II. INCORPORATION OF 14 CH 3 SCH 2 CH 2 CH(NH 2 )CO 2 H INTO VARIOTIN (1962) (2)
An antibacterial substance from several strains of penicillia and its probable identity with penicillin. (1948) (2)
STUDIES ON THE MECHANISM OF THE AGGLUTINATION IV. THE AGGLUTININ ATTACHING TO THE BACTERIA IN THE PROZONE AND THE SIZE OF THE AGGLUTININ (1948) (2)
Thirty-five Years with Bioactive Microbial Products (1979) (2)
RAROMYCIN, A NEW TUMOR-INHIBITORY ANTIBIOTIC PRODUCED BY A STREPTOMYCES (1958) (2)
Synthesis of 3''-deoxydihydrostreptomycin active against resistant bacteria. (1976) (2)
On antitumor effect of sarkomycin-INH. (1958) (1)
[Future of chemotherapy]. (1969) (1)
STUDIES ON BIOSYNTHESIS OF 3-AM1NO-3-DEOXY-D -GLUCOSE (2006) (1)
The influence of the phenylacetic acid, paranitrophenylacetic acid, paraaminophenylacetic acid and paraoxyphenylacetic acid on the penicillin production by surface culture. (1948) (1)
Biogenesis of C13-hydroxy acid moiety of variotin. (1962) (1)
Letter: New components of bleomycin. (1973) (1)
Studies on the influence of penicillin and patulin on the respiration of bacteria. (1948) (1)
Prumycin produced by Bacillus cereus. (1983) (1)
Structural studies on griseolutein B, phenazine antibiotic. (1957) (1)
Studies on structure and activity of kanamycins and kanamycin-related compounds. (1968) (1)
Antibiotics produced by Nocardia mesenterica and a new antibiotic, mesenterin. (1955) (1)
Studies on antitumor antibiotics. (1959) (1)
Letter: Hydroxypepstatin, a new peptatin produced by Streptomyces. (1973) (1)
A new method of testing the potency of tuberculin. (1948) (1)
SYNTHESIS OF 5“-DEOXY-5”-FLUOROLIVIDOMYCIN B (1983) (1)
Studies on mikamycins. (1963) (1)
STEREOSPECIFIC TRANSFORMATION OF D-SUGAR TO L-SUGAR IN COMPLEX AMINOGLYCOSIDE. SYNTHESIS OF KANAMYCIN B ANALOG HAVIN 2,6-DIAMINO-2,4,6-TRIDEOXY-L-ARABINO-HEXOPYRANOSE (1981) (1)
Syntheses of 6', 5'', 6''''-triamino-6', 5'', 6''''-trideoxylividomycin A and 6', 5''-dideoxylividomycin B. (1976) (1)
Development of resistance and cross resistance relation between kanamycin and streptomycin. (1959) (1)
Bottromycin action on macromolecular biosynthesis. (1967) (1)
Structure-Activity Study on the Kasugamycin Family (1976) (1)
ON THE MOLECULAR FORMULA AND BACTERIOSTATIC ACTION OF CHLOROMYCETIN (1949) (1)
Studies on antitumor substances of microbial origin. (1961) (1)
Amidinomycin from Streptomyces kasugaensis producing kasugamycin. (1968) (1)
Letter: Preparation of bleomycinic acid: hydrolysis of bleomycin B2 by a Fusarium acylagmatine amidohydrolase. (1973) (1)
[Uptake and translocation of 14C-labelled Kasugamycin in rice plants]. (1967) (1)
SYNTHETIC STUDIES ON AN ANTITUMOR ANTIBIOTIC, BLEOMYCIN. XIII. SYNTHESIS OF 2-FORMYLPYRIMIDINE, A KEY INTERMEDIATE FOR THE PYRIMIDINE MOIETY OF BLEOMYCIN (1985) (1)
ISOLATION AND PROPERTIES OF VALANIMYCIN, A NEW (2006) (1)
A product of Streptomyces exhibiting strong inhibition against Ehrlich carcinoma cells in vitro. (1959) (1)
Degradation studies on danomycin. (1966) (1)
TRANSFORMATION OF DIHYDROSTREPTOMYCIN INTO 3“-DEOXYDIHYDROSTREPTOMYCIN (1981) (1)
[Secondary microbial metabolites with potentials for antineoplastic actions: antineoplastic antibiotics and immunopotentiators]. (1983) (1)
Bestatin: A Low Molecular Immunomodifier (1986) (1)
[Anti-tumour effects of sarkomycin]. (1954) (1)
Kanamycin and other water-soluble basic antibiotics. (1960) (1)
[Progress in basic studies of kanamycin. I. Structure and biosynthesis]. (1967) (1)
In a new antibiotic,exfoliatin,produced by a strain of streptomyces (1952) (1)
Syntheses of 2′,3′-Dideoxykanamycin A, 2′,3′-Dideoxyamikacin and Related Substances (1987) (1)
Effect of oudenone on adrenal tyrosine hydroxylase activity in vivo and on tissue catecholamine concentrations. (1971) (1)
Preferential effects of antibiotics on E. coli strains carrying plasmids. (1974) (1)
TOTAL SYNTHESIS OF DEGLYCOBLEOMYCIN A2 (1981) (1)
Man-designed bleomycins. Iron complexation and nucleotide sequence cleavage by synthetic models of bleomycin (1988) (1)
Studies on New Microbial Secondary Metabolites with Potential Usefulness: Antibiotics, Enzyme Inhibitors, and Immunomodifiers (1984) (1)
[Antitumor effect of bestatin combined with bleomycin against hepatoma AH 66 subcutaneously transplanted in rats]. (1984) (1)
[Origin and bases of cancer chemotherapy (author's transl)]. (1978) (1)
Production and Isolation of Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (1)
Synthesis of (14R)‐ and (14S)‐14‐De(hydroxymethyl)‐14‐hydroxymycaminosyl Tylonolides. (1987) (1)
Total Syntheses of Indicine N‐Oxide, Intermedine N‐Oxide, and Their Enantiomers Using Carbohydrate as a Chiral Educt. (1988) (1)
Bacteriological and pharmacological studies on methanesulfonates of kanamycin and fradiomycin (neomycin). (1959) (1)
STUDIES ON THE MECHANISM OF THE AGGLUTINATION (1948) (1)
Synthesis and antitumor activity of 4'-O-acylanthracyclines. (1992) (1)
Studies on metabolism of a chloramphenicol-producing Streptomyces with chlorine-36. (1959) (1)
Studies on bleomycin. (1967) (1)
Relative deficiency of serine proteinase activities in spleen of aged mice (1987) (1)
Production of 3-carboxy-2,4-pentadienal lactol by a streptomyces and its antitumor activity. (1962) (1)
INHIBITION OF RESISTANT DYSENTERY BACILLI BY PHLEOMYCIN. (1963) (1)
[Some antineoplastic substances produced by microorganisms]. (1962) (1)
Bestatin, a low molecular weight immunomodifier produced by microorganisms (1987) (1)
Specific inhibition of aspartase by S-2,3-dicarboxyaziridine. (1988) (1)
Studies on the effects of griseolutein B. (1953) (1)
Raromycin, a new tumorinhibitory antibiotic produced by a Streptomyces. I. Studies with Ehrlich carcinoma and Croker sarcoma 180 of mice. (1957) (1)
STUDIES ON THE MUTATION OF STREPTOMYCES GRISEUS NO. 200 BY X-RAY IRRADIATION (1950) (1)
Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products (1973) (1)
Recent Studies on Antitumor Antibiotics (1979) (1)
Inactivation of aminoglycosidic antibiotics by resistatt organisms. (1968) (1)
Biological studies on mikamycin. III. Influence of blood on the activity and further investigations on the activity against experimental infections. (1962) (1)
[Effects of mitomycin and some other substances produced by streptomyces upon Yoshida sarcoma]. (1953) (1)
Serum dopamine-β-hydroxylase in spontaneously hypertensive rats (1972) (1)
ISOLATION OF PENICILLIN G N-ETHYLPIPERIDINE SALT AND SODIUM SALT AND THEIR STABILITY (1948) (0)
Leupeptine and their analogues (1969) (0)
Inhibition of the bacteriostatic effect of kanamycin by brain. (1959) (0)
Process for the preparation of adriamycin-4'-O-derivatives or acid addition salts thereof (1981) (0)
Inhibition of dopamine beta-hydroxylase by aquayamycin. (1968) (0)
A compound with anti-tumor effect and antimicrobial effect, its microbiological production, and its use as a medicament (1986) (0)
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[Prospects in the development of antibiotic agents]. (1981) (0)
Immobilized phenylalanine hydroxylase through the SH groups. (1986) (0)
A process for the preparation of O-acyl josamyciner. (1969) (0)
Derivatives of antibiotics of the pluramycin group, their preparation and use (1985) (0)
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New analgesic agent (1981) (0)
Spergualinaehnliche compounds and manufacturing processes it. (1987) (0)
Proceedings: Serum dopamine beta-hydroxylase activity in developing spontaneously hypertensive rats and the effect of salt administration. (1975) (0)
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Method for the preparation of 4 o tetrahydropyranyladriamycin b us patent 4818818 april 4 1989 (1989) (0)
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SYNTHESES OF 1-EPIKANAMYCIN A AND ITS 1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL) DERIVATIVE (1983) (0)
Correlation between serum dopamine-beta-hydroxylase activity and dopamine-beta-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands. (1977) (0)
Leucylnegamycin, an antibiotic from negamyhcin-producing Streptomyces. (1971) (0)
Cellular uptake and efflux and cytostatic activity of 4'-O-tetrahydropyranyladriamycin in adriamycin-sensitive and resistant tumor cell lines.:IN ADRIAMYCIN-SENSITIVE AND RESISTANT TUMOR CELL LINES (1984) (0)
Bisukaberin, foerfarande Foer the arm in a production foerening and also its anvaendning som laekemedel. (1987) (0)
BIOGENESIS OF VARIOTIN:I. INCORPORATION OF CH 3 14 CO 2 H AND 14 CH 3 CO 2 H INTO VARIOTIN (1962) (0)
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Process for the preparation of N- (4- (3-aminopropyl) aminobutyl) -2- (omega-guanidino-fatty acid-amido) -2-substituted-ethanamide (1982) (0)
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STUDIES ON AMINOSUGARS PART 35, SYNTHESES OF 3′,4′-DIDEOXYNEAMINE AND 3′- AND 4′-O-METHYLNEAMINES (1974) (0)
Crystalline gamma-bestatin and process for its preparation (1982) (0)
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New process of producing tobramycin or 3'-deoxy-kanamycin ba from a protected derivative of kanamycin b, and intermediate products obtained during such process (1980) (0)
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SYNTHESIS OF 2-AMINO-3-(2-OXO-4-PHENYL-1-AZETIDINYL)PROPIONAMIDE (1981) (0)
Process for the preparation of 3 ', 4'-dideoxykanamycin B and protected kanamycin B derivatives for use as starting material in the process (1976) (0)
SYNTHESIS OF COFORMYCIN, STRUCTURE OF COFORMYCIN, AN UNUSUAL NUCLEOSIDE OF MICROBIAL ORIGIN (1974) (0)
The antibiotic MF 730-N6, its preparation, the microorganism to be used thereby, as well as its use for the preparation of medicinal products (1986) (0)
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A process for the preparation of antibiotics aclacinomycin A and / or B, or salts thereof or deoxyribonucleinsyrekomplekser. (1975) (0)
STEREOSELECTIVE SYNTHESIS OF (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYLPENTANOIC ACID, AN AMINO ACID CONSTITUENT OF BLEOMYCIN, BY ALDOL CONDENSATION (1982) (0)
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Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis. (1970) (0)
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2-Amino-5-methyl-5-hexenoic acid, a methionine analog produced by Streptomyces sp. MF374-C4. (1979) (0)
SYNTHESIS OF 1‐N‐((S)‐4‐AMINO‐2‐HYDROXYBUTYRYL)‐3′‐DEOXYRIBOSTAMYCIN (3′‐DEOXYBUTIROSIN B) (1977) (0)
Analgesic action of enkephalinase inhibitor, D-phenylalanyl-2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid (D-Phe-AHPA) (1983) (0)
A process for the preparation of a optically active monoalkyl ester of ss- (s) -aminoglutarsaeure (1981) (0)
Separation chemistry of various elements produced by heavy-ion irradiation (1974) (0)
Benz (a) anthraquinone compounds, microbial processes for their manufacture and their use as pharmaceuticals. (1986) (0)
Cylinder plate assay and some studies of isonicotinic acid hydrazide with M. tuberculosis 607. (1952) (0)
Istamycine and method for manufacturing the same (1980) (0)
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L-argininalderivate, processes for their preparation and pharmaceutical compositions containing them (1981) (0)
Novel derivatives of istamycins a and b and process for their preparation and pharmaceutical application (1981) (0)
Spergualinderivater, process for their preparation, pharmaceutical composition in which they are incorporated, and a method for preparing the composition (1992) (0)
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Lignan Lactone Antitumor Agents. Part 4. Synthesis of Glycosidic Lignan Variants Related to α‐Peltatin. (1988) (0)
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[Discovery of dibekacin and its chemical aspects]. (1982) (0)
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STRUCTURE AND SYNTHESIS OF DOPASTIN, AN INHIBITOR OF DOPAMINE BETA-HYDROXYLASE (1975) (0)
Summary of Structures of Microbial Secondary Metabolites Determines by Dr. H. Umezawa (1979) (0)
Synthesis of 3′‐Deoxy‐3′‐fluorokanamycin A* and 3′,4′‐Dideoxy‐3′‐ fluorokanamycin A. (1992) (0)
Spergualin derivatives and their use for the preparation of drugs with immunosuppressive activity (1985) (0)
NEW ANTHRACYCLINE ANTIBIOTICS: SERIRUBICIN AND 1-H YDROXY SER IR UBI CIN t (2006) (0)
N- (4- (3-aminopropyl) aminobutyl) -2- (w-guanidino fatty acid amido) -2-substituted ethanamide, their salts and processes for their preparation (1982) (0)
Sorbents for protease and verfaren for cleaning of tissue plasminogen activator with it. (1985) (0)
Anthracycline derivatives, methods for their manufacture and their use as pharmaceuticals. (1987) (0)
Chemistry of the transplutonium elements (1974) (0)
Tylosin derivatives and process for their preparation (1981) (0)
2'-modified kanamycin, processes for making them, as well as medium having antibacterial activity which comprise these modified kanamycin (1982) (0)
STUDIES ON THE EXTRACTION OF PENICILLIN (1948) (0)
New derived n-methanesulfonic the demethyl-3-O istamycin b, their preparation and therapeutic compositions containing (1983) (0)
Analogifremgangsmaade for the preparation of (-) - 15-deoxyspergualing and pharmaceutically acceptable syreadditionsssalte thereof as well as intermediate (1983) (0)
Derived from l-argininal and method of preparing (1981) (0)
Synthesis of 2′,3′-Dideoxy-2′-fluorokanamycin A (I). (1986) (0)
An N- (6-substituted pyridine-2-carbonyl) -3-substituted histidine derivative, process for its preparation and its use as an anti-tumor agent (1985) (0)
SYNTHESIS OF 3′‐DEOXYKANAMYCIN B (TOBRAMYCIN) (1977) (0)
[Chemical modification of 3' and 4' positions and antitumor activities of anthracyclines]. (1988) (0)
Using spergualin or one of its pharmaceutically acceptable salts for the manufacture of a transplantation immunity unterdrueckenden and anti-allergic agent. (1985) (0)
A Synthetic Approach to the Mechanism of DNA-Cleavage by Bleomycic-Fe(II)-O2 Complex (1984) (0)
Messenger RNA-associated 30S ribosomal subunit: extraction from E. coli and the effect of chloramphenicol on the content. (1968) (0)
Novel aminoglycosidic antibiotics, methods of production thereof and antibacterial compositions comprising them (1980) (0)
Anthracycline derivatives, their preparation and use (1987) (0)
Chemistry of bleomycin. XXVIII. Preparation of deglycobleomycin by mild acid hydrolysis of bleomycin. (1981) (0)
Process for the preparation of 3,4i-dideoxykanamycin] (1976) (0)
[RECENT TRENDS IN ANTICARCINOGENIC ANTIBIOTICS]. (1964) (0)
A process for the preparation of antibiotics of phleomycingruppen. (1973) (0)
Total Synthesis of PDE-I (2008) (0)
bmg162-af2 particular antibiotic having antitumor activity and process for its preparation from a strain of the genus bacillus (1981) (0)
SYNTHESIS OF A LIVIDOMYCIN B ANALOG, 5-O-(3-O-(2-AMINO-2-DEOXY-α-D-GLUCOPYRANOSYL)-β-D-RIBOFURANOSYL)-3′-# DEOXYPAROMAMINE (1977) (0)
67 CHEMICAL STUDIES ON MINOSAMINOMYCIN (1975) (0)
A process for preparing an antibiotic BMG 162-AF2. (1981) (0)
Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part II - Small molecular weight immunomodulators produced by microorganisms. (1982) (0)
Analogifremgangsmaade for the preparation of an N-oe4- (3-aminopropyl) aminobutylaa-2- (omega-guanidino-fedtsyreamido) -2-substituted ethanamide or a salt thereof (1982) (0)
Antifungal substances, phaeofadin and moldin, produced by Streptomyces. (1952) (0)
Ka~amycin, Mechanism of Resistance to Aminoglycasides and Development of Derivatives Active Against Resistant Strains: (1979) (0)
Spergualinbeslaegtede compounds or physiologically acceptable salts thereof, their preparation and use (1986) (0)
Plipastatin, its preparation and use, as well as in the manufacture useful microorganism (1985) (0)
Spergualin related compounds, Methods for their preparation and their use as medicaments (1983) (0)
SYNTHESIS OF A MASKED DERIVATIVE OF 3′‐DEOXYDIHYDROSTREPTOBIOSAMINE, A PRECURSOR FOR THE SYNTHESIS OF 3′‐DEOXYDIHYDROSTREPTOMYCIN (1977) (0)
Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part I - Antitumor antibiotics and their derivatives. (1982) (0)
A process for the preparation of 3 ', 4'-dideoxy-kenamycin B. (1971) (0)
(Received for publication November 25, 1977) Activities of derivatives of dehydrodicaffeic acid dilactone (DDCAD) to inhibit catechol- 0-methyltransferase (COMT), cyclic AMP phosphodiesterase (PDE) and DOPA decarboxy- (2006) (0)
Effects of antitumor substances on yeasts and their respiration deficient mutants. (1958) (0)
Preparation of branched 2-deoxy-alpha-glycosides (1976) (0)
The method and the starting material for the preparation of bestatinderivater (1985) (0)
VOL. XXI NO. II THE JOURNAL OF ANTIBIOTICS 653 ORYZOXYMYCIN, A NEW ANTIBIOTIC (2006) (0)
The action of raromycin, a new tumor-inhibitory antibiotic, on transplantable mouse tumors. (1957) (0)
Preparation of 1,2-dihydro-3h-pyrrolo3,2-eindole derivative (1978) (0)
A process for preparing an antibiotic substance, kasugamycin, as well as acid addition salts thereof. (1964) (0)
New antibiotic aminoglycoside derivative has istamycin, process for the preparation and pharmaceutical compositions containing (1981) (0)
TOTALSYNTH. VON KASUGAMYCIN (1972) (0)
Cross resistance relation between streptomycin and kanamycin in E. coli and Mycobacterium 607. (1959) (0)
Mutagenicities of bleomycin derivatives on Salmonella typhimurium TA102 (1984) (0)
A specific protease inhibitor from Streptomyces. (1986) (0)
STUDIES ON AMINOSUGARS PART 41, SYNTHESIS OF 1‐N‐((S)‐4‐AMINO‐2‐HYDROXYBUTYRYL)‐3′,4′‐DIDEOXYNEAMINE (1975) (0)
A process for the preparation of 2'-amino-2'-deoxy-kanamycin. (1968) (0)
Pharmacological action of FD-008, a new dopamine-beta-hydroxylase inhibitor. III. Effects on endogenous biogenic amine levels in rats. (1975) (0)
Method of determination of chlortetracycline and some studies on use of chlortetracycline for fish preservation. (1957) (0)
Ion-exchange chromatography of aminoglycoside antibodies. (1975) (0)
Studies on Lignan Lactone Antitumor Agents. Part 1. Synthesis of Aminoglycosidic Lignan Variants (II) Related to Podophyllotoxin (I). Studies on Lignan Lactone Antitumor Agents. Part 2. Synthesis of N-Alkylamino- and 2,6-Dideoxy-2-ami (1987) (0)
THIRTY-FIVE YEARS WSTH BIOACTIVE MICROBIAL (0)
SYNTHESIS OF 1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL)LIVIDOMYCIN A (1975) (0)
Spergualin-related compounds having a phenylene group, process for their preparation as well as a pharmaceutical composition (1985) (0)
Process for the preparation of 4'-O-tetrahydropyranyladriamycin b (1986) (0)
SYNTHESIS OF CLEONINE (AMINO(1‐HYDROXYCYCLOPROPYL)ACETIC ACID), A NOVEL AMINO ACID CONTAINED IN CLEOMYCIN (1981) (0)
Antibiotics containing the beta—lactam structure, part 1: by A. L. Demain and N. A. Solomon, Springer Verlag, 1983. DM280 (xvi + 358 pages) ISBN 3 540 12107 2 (1984) (0)
List of New Antibiotics and Their Derivatives Discovered by Dr. Hamao Umezawa (1979) (0)
[Preparation of negamycin ointments. I. Possible utility of gel bases]. (1986) (0)
ON MURINE TRANSPLANTABLE TUMORS AND MICROBIAL INFECTIONS (2006) (0)
A process for preparing bestatin gamma-form crystal (1982) (0)
[Chemotherapy by antibiotics]. (1970) (0)
TOTAL SYNTHESIS OF THE DISACCHARIDE OF BLEOMYCIN, 2-O-(α-D-MANNOPYRANOSYL)-L-GULOPYRANOSE (1981) (0)
SYNTHESES OF BESTATIN AND ITS ANALOGS AND THEIR BIOACTIVITY (1981) (0)
STUDIES ON AMINOSUGARS PART 36, SYNTHESES OF 3′,4′-DIDEOXY- AND 3′,4′,5′-TRIDEOXY-RIBOSTAMYCIN (1973) (0)
BIOGENESIS OF VARIOTIN I. INCORPORATION OF CH314C02H AND 14CH 3CO2H INTO VARIOTIN (2006) (0)
A process for the preparation of blasticidin S and its addition products (1961) (0)
THEORETICAL STUDIES ON THE END POINT CURVE OF ROD-SHAPED PARTICLES IN ULTRAFILTRATION (1948) (0)
Derivatives of aminopropylaminobleomycine their therapeutic applications and process for their preparation (1982) (0)
ON THE NEW SOURCE OF CILOROMYCETIN, (2009) (0)
[Preparation of negamycin ointments. II. Improvement in stability and antimicrobial activity]. (1986) (0)
IRON COMPLEXES OF BLEOMYCIN AND DEGLYCO-BLEOMYCIN : SPECTROSCOPIC PROPERTIES AND NUCLEOTIDE SEQUENCE SPECIFICITY IN DNA CLEAVAGES (1983) (0)
Mouse leukemia C1498 and antitumor substances. (1959) (0)
process new derivatives of kanamycin A, as well as manufacturing the same (1981) (0)
Tissues Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Concentration in ug (2006) (0)
L-argininal derivatives and preparation method (1981) (0)
N- (4- (3-aminopropyl) aminobutyl) -2,2-dihydroxyaethanamid and methods for its synthesis (1982) (0)
PERSPECTIVES ON RESEARCH OF ANTIBIOTICS AND LOW MOLECULAR WEIGHT ENZYME INHIBITORS (1983) (0)
Presence of immunosuppressive agents with various activities in Ehrlich ascites fluid. (1975) (0)
Studies on Glycosylation of erythro-β-Hydroxy-L-histidine. A Key Step of Bleomycin Total Synthesis. (1986) (0)
Regio-Specific Total Synthesis of (±)-2-Hydroxyaklavinone. Synthetic Approaches to New Anthracyclines: 4,11-Dideoxy-2-hydroxy-β-rhodomycinone and Its Glycosides. (1984) (0)
Spergualinderivater, process for their preparation and their use as medicaments (1987) (0)
THE JOURNAL OF ANTIBIOTICS BIOSYNTHESES OF NEW BLEOMYCINS (2006) (0)
Aclacinomycins A and B and processes for their preparation (1975) (0)
SALMONELLA ALACHUA , A NEW SEROTYPE 1 WILLA (0)
Goriolin B was oxidized by chromic anhydride in acetic acid at 20-'30°C for 16~ (2007) (0)
Synthesis of 3'- and 4'-O-methylneamine. (1972) (0)
Process for the preparation of an antibiotic, bmg162 AF2, or a pharmaceutically acceptable salt thereof (1981) (0)
Derivatives of tylosin (1981) (0)
Anthracyclines new glycosides and their pharmacological application (1977) (0)
Synthesis of 3-Deazaoxanosines, C-Nucleoside Isosteres of Oxanosine. (1986) (0)
Synthetic Studies on Pyrrolizidine Alkaloid Antitumor Agents. Enantioselective Synthesis of Retronecine (I) and Its Enantiomer (II) from D-Glucose. (1986) (0)
United States Patent ( 19 ) Akita (2017) (0)
Development of microbial secondary metabolites with potential usefulness (1984) (0)
Streptovaricin- and rifampicin-resistance of RNA polymerase in a resistant clone of Escherichia coli B. (1968) (0)
Letter: Fusaric acid derivatives: the effect on dopamine beta-hydroxylase. (1973) (0)
Antibiotic bmg162-AF2, process for its preparation and pharmaceutical preparation containing anti-tumor activity (1981) (0)
Therapeutically useful compounds as well as processes for their preparation (1969) (0)
Studies of the Effect of Spermidine in Enhancing Cellular Immunity (1982) (0)
Bisucaberin, method for its production and its use as a medicinal product (1987) (0)
A process for preparing anthracyclinglycosidantibiotika designated MA-144 and MA 144 m1-m2 or non-toxic acid addition salts or complexes with deoxyribonucleic acid (1977) (0)
INHIBITION OF TYROS 1 NE HYDROXYLASE BY AQUAYAMYCIN (2006) (0)
Novel threo-3-amino-2-hydroxybutanoylaminoacetic acid (1979) (0)
Mode of action of enomycin, an antitumor antibiotic of high molecular weight. 3. On the weak inhibition of polyphenylalanine synthesis directed by polyuridylic acid. (1968) (0)
STUDIES ON AMINOSUGARS PART 40, SYNTHESIS OF BUTIROSIN B AND ITS 3′,4′-DIDEOXY DERIVATIVE (1975) (0)
SYNTHESIS OF 6′-AMINO-1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL)-6′-DEOXYLIVIDOMYCIN A (1975) (0)
Foerfarande Foer framstaellning of tumoerfoerhindrande baumycinkomplexet and also its Komponenter (1977) (0)
Bisucaberin, procedure for its preparation and its use as a medicinal product (1987) (0)
New process for the preparation of 1-n-isoseryl- or 1-n- (l-4-amino-2-hydroxybutyryl) -3 ', 4'-didesoxykanamycin b and its intermediates zeue (1979) (0)
Streptomyces galbus nov. sp. and some remarks on Streptomyces producing streptomycin-group antibiotics. (1959) (0)
Test methods for antitumor substances. (1961) (0)
The Total Synthesis of (-)-Indicine N-Oxide (I) and Intermediate N-Oxide. (1987) (0)
Isocoformycin and a method for preparation thereof (1978) (0)
A kinetic aspect of the antibody production against Ehrlich tumor cells in mice bearing Ehrlich solid tumor. (1975) (0)
The new, physiologically active substance ebelactone and method for manufacturing the same (1981) (0)
Enzymatic Changes in Pancreas and Liver of the KK Mouse As an Animal Model of Diabetes Mellitus (1986) (0)
Screening of Enzyme Inhibitors with Potential Antitumor Activity (1976) (0)
1N-(.alpha.-HYDROXY-.omega.-AMINOALKANOYL)-6'N-METHYL-3',4'-DIDEOXYKANAMYCIN B AND THE PRODUCTION THEREOF (1975) (0)
2,6-diphenyl-3,7-dioxabicyclo-3.3.0-octane 4,8-dione derivative and anticarcinogens, catechol-o-methyl transferase inhibitors and adenosine 3',5'-cyclic phosphoric acid phosphodiesterase inhibitors containing the derivative as active component (1977) (0)
[Specific enzyme inhibitors synthesized by micro-organisms]. (1971) (0)
Siastatin B, a Potent Neuraminidase Inhibitor: The Total Synthesis and Absolute Configuration. (1989) (0)
[Research progress of secondary metabolites produced by microorganisms--enzyme inhibitors (author's transl)]. (1976) (0)
Letter: Synthesis of 4-amino-3-hydroxy-6-methylheptanoic acid, an amine component of pepstatin. (1973) (0)
CATECHOLAMINE SYNTHESIZING ENZYMES IN HYPERTENSION (1976) (0)
Foerfarande Foer framstaellning of antibiotika aklacinomyciner a and b eller blandningar daerav with antitumor Effect (1975) (0)
bleomycinique acid substituted on the nitrogen of the amido group (1983) (0)
Mode of resistance and structure-activity. (1968) (0)
Papers of Dr. Hamao Umezawa (1979) (0)
Studies on antifungal substances, phaefacin and moldin, produced by Streptomyces sp. (1952) (0)
Makrolide Antibiotika-Derivate (1983) (0)
[Basic information and clinical application of Kanendomycin]. (1969) (0)
[Progress in basic studies of kanamycin. II. Activity, structure and tolerance mechanism]. (1967) (0)
Selected Papers of Dr. Hamao Umezawa (1979) (0)
1-n - ((s) -alpha-substituted omegaaminoacyl) -neamine or -ribostamycine and methods of making the same (1973) (0)
Letter: Four minor antibiotics from macarbomycins. (1973) (0)
Studies on the potency test of penicillin; on the error in the cup assay and Miyamura's rapid method. (1948) (0)
The Crystal Structure of Formyein Hydrobromide Monohydrate (2001) (0)
[Biochemical effects of 3',4'-dideoxykanamycin B]. (1973) (0)
New derivatives of n-methanesulfonic istamycines a and b, their preparation and therapeutic compositions based on these derivatives (1981) (0)
N- (4- (3-aminopropyl) aminobutyl) -2- (o-guanidino (fatty acid) amido) -ethanamides substituted in position 2 and their salts, process for their preparation and their therapeutic application (1982) (0)
Kanamycins MODIFIED 2 ', their process of preparation and their use as antibacterial agents (1982) (0)
Bestatin: a crystal and molecular structure (1981) (0)
1127 – ENZYME INHIBITORS OF MICROBIAL ORIGIN (1977) (0)
Letter: Immobilization of phosphotransferases obtained from resistant bacteria. (1974) (0)
New process for the preparation of 3'-desoxykanamycin a (1981) (0)
New physiologically active substance erbstatin analogous compounds (1987) (0)
Anthracycline derivatives, to processes for their preparation and their use as medicaments. (1987) (0)
New physiologically active derivatives of esterastins and method for manufacturing the same (1979) (0)
Process for the preparation of agents antiotiske (1977) (0)
3- (4'-aminobutylamino) propylamino-bleomycin derivatives, their preparation and their use as medicaments (1984) (0)
Anthracycline glycosides, methods for their production and drug (1977) (0)
REGIO- AND STEREOSPECIFIC SYNTHESIS IN THREO-3-AMINO-2-HYDROXY ACIDS, NOVEL AMINO ACIDS CONTAINED IN AMINOPEPTIDASE INHIBITORS OF MICROBIAL ORIGIN (1980) (0)
Analogifremgangsmaade for the preparation of compounds spergualinbeslaegtede (1983) (0)
Discovery of josamycin. (1982) (0)
34 SYNTHETIC APPROACH TO BLEOMYCIN (BLM) (1980) (0)

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