Hamao Umezawa
#57,390
Most Influential Person Now
Hamao Umezawa's AcademicInfluence.com Rankings
Download Badge
Chemistry
Hamao Umezawa's Degrees
- PhD Chemistry University of Tokyo
Why Is Hamao Umezawa Influential?
(Suggest an Edit or Addition)Hamao Umezawa's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- New antibiotics, bleomycin A and B. (1966) (696)
- Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. (1976) (662)
- Pepstatin, a new pepsin inhibitor produced by Actinomycetes. (1970) (600)
- Structures and activities of protease inhibitors of microbial origin. (1976) (415)
- Formation and reversion of Streptomycete protoplasts: cultural condition and morphological study. (1974) (316)
- On the mechanism of action of bleomycin: scission of DNA strands in vitro and in vivo. (1969) (300)
- Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus (1986) (240)
- Studies on a new epidermal growth factor-receptor kinase inhibitor, erbstatin, produced by MH435-hF3. (1986) (212)
- A new antitumor antibiotic, spergualin: isolation and antitumor activity. (1981) (202)
- Low-molecular-weight enzyme inhibitors of microbial origin. (1982) (196)
- Mechanism of action of bleomycin. Studies with the growing culture of bacterial and tumor cells. (1968) (182)
- Enzyme inhibitors of microbial origin (1972) (181)
- Tetrahydropyranyl derivatives of daunomycin and adriamycin. (1979) (181)
- Studies on bleomycin (1969) (181)
- Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. (1984) (175)
- Studies on the mechanism of antitumor effect of bleomycin of squamous cell carcinoma. (1972) (174)
- Purification of bleomycins. (1966) (170)
- Production and isolation of a new antibiotic: kanamycin. (1957) (167)
- Screening of agents which convert 'transformed morphology' of Rous sarcoma virus-infected rat kidney cells to 'normal morphology': identification of an active agent as herbimycin and its inhibition of intracellular src kinase. (1985) (158)
- A THERMOLYSIN INHIBITOR PRODUCED BY ACTINOMYCETES: PHOSPHORAMIDON (1973) (157)
- Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes. (1972) (146)
- Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase. (1976) (142)
- Activity and toxicity of bleomycin. (1967) (138)
- Inhibition of DNA-dependent RNA synthesis by rifamycins. (1968) (137)
- ON THE MECHANISM OF ACTION OF BLEOMYCIN (1970) (133)
- Letter: Syntheses of 1-n-(S)-4-amino-2-hydroxybutyryl)-kanamycin B and -3', 4'-dideoxykanamycin B active against kanamycin-resistant bacteria. (1973) (131)
- The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNA. (1969) (130)
- Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor. (1967) (129)
- Ascorbic acid and adriamycin toxicity. (1991) (127)
- The structure of bestatin. (1976) (127)
- Effect of bestatin on mouse immune system and experimental murine tumors. (1980) (125)
- Studies on marine microorganisms. V. A new antibiotic, aplasmomycin, produced by a streptomycete isolated from shallow sea mud. (1976) (125)
- Chemistry of bleomycin. XXI. Metal-complex of bleomycin and its implication for the mechanism of bleomycin action. (1978) (123)
- New antifungal antibiotics, benanomicins A and B from an actinomycete. (1988) (122)
- Chemistry of bleomycin. XX. The X-ray structure determination of P-3A Cu(II)-complex a biosynthetic intermediate of bleomycin. (1978) (121)
- 3',4'-dideoxy-kanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa. (1971) (120)
- GHYMOSTATIN, A NEW GHYMOTRYPSIN INHIBITOR PRODUCED BY ACTINOMYGETES (1970) (117)
- Bleomycin and other antitumor antibiotics of high molecular weight. (1965) (117)
- Structure of an antitumor antibiotic, spergualin. (1981) (112)
- Antitumor anthracycline antibiotics, aclacinomycin a and analogues. II. Structural determination. (1979) (100)
- The structure of pepstatin. (1970) (99)
- Natural and artificial bleomycins: chemistry and antitumour activities (1971) (98)
- Biochemical mechanism of resistance to aminoglycosidic antibiotics. (1974) (98)
- NEW ANTIBIOTICS, BLEOMYCIN A & B (1966) (98)
- ANTITUMOR ANTHRACYCLINE ANTIBIOTICS, ACLACINOMYCIN A AND ANALOGUES (1979) (97)
- A bleomycin-inactivating enzyme in mouse liver. (1974) (96)
- The structure of aquayamycin. (1970) (96)
- Breaks and rejoining of DNA in cultured mammalian cells treated with bleomycin. (1970) (95)
- Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes. (1973) (93)
- Serum dopamine β-hydroxylase activity in developing hypertensive rats (1974) (91)
- Decrease of melting temperature and single strand scission of DNA by bleomycin in the presence of 2-mercaptoethanol. (1969) (90)
- The structural studies of formycin and formycin B. (1966) (89)
- Studies on bleomycin: chemistry and the biological action. (1973) (88)
- Bleomycin : current status and new developments (1978) (87)
- Negamycin, a novel hydrazide antibiotic. (1971) (87)
- Reduction of adriamycin toxicity by ascorbate in mice and guinea pigs. (1982) (87)
- Possible control of formation of aerial mycelium and antibiotic production in Streptomyces by episomic factors. (1970) (86)
- Chemistry of bleomycin. XVIII. carbon-13 NMR studies. (1977) (86)
- Mannostatins A and B: new inhibitors of alpha-D-mannosidase, produced by Streptoverticillium verticillus var. quintum ME3-AG3: taxonomy, production, isolation, physico-chemical properties and biological activities. (1989) (85)
- Synthesis and antitumor activity of spergualin analogues. I. Chemical modification of 7-guanidino-3-hydroxyacyl moiety. (1985) (85)
- Chemistry and mechanism of action of bleomycin. (1974) (84)
- An active intermediate formed in the reaction of bleomycin-Fe(II) complex with oxygen. (1981) (84)
- Production of actinonin, an inhibitor of aminopeptidase M, by actinomycetes. (1985) (84)
- A plasmid involved in chloramphenicol production in Streptomyces venezuelae: evidence from genetic mapping. (1975) (84)
- Purification and characterization of a sialidase inhibitor, siastatin, produced by Streptomyces. (1974) (83)
- Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination. (1987) (82)
- Antitumor activity of new anthracycline antibiotics, aclacinomycin-A and its analogs, and their toxicity. (1977) (81)
- Index of antibiotics from actinomycetes (1967) (81)
- A new antibiotic, azomycin. (1953) (81)
- Isolation and structure of kanamycin inactivated by a cell free system of kanamycin-resistant E. coli. (1967) (80)
- Synthesis of (-)-15-deoxyspergualin and (-)-spergualin-15-phosphate. (1982) (79)
- Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. I. Taxonomy, production, isolation and preliminary characterization. (1986) (78)
- Rapid uptake by cultured tumor cells and intracellular behavior of 4'-O-tetrahydropyranyladriamycin. (1983) (77)
- Mitogenic effect of bestatin on lymphocytes. (1980) (75)
- Recent advances in bioactive microbial secondary metabolites. (1977) (75)
- New aminoglycoside antibiotics, istamycins A and B. (1979) (74)
- A glyoxalase I inhibitor of a new structural type produced by Streptomyces. (1975) (73)
- Lethal effect of bleomycin on cultured mammalian cells. (1970) (72)
- Adenylylstreptomycin, a product of streptomycin inactivated by E. coli carrying R factor. (1968) (71)
- Binding of bleomycin to DNA in bleomycin-sensitive and -resistant rat ascites hepatoma cells. (1975) (71)
- Structures of new antibiotics napyradiomycins. (1986) (70)
- Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. I. Taxonomy of the producing organism, isolation and biological properties. (1987) (70)
- Esterastin, an inhibitor of esterase, produced by actinomycetes. (1978) (68)
- The total syntheses of negamycin and the antipode. (1972) (67)
- Effect of bleomycin on mammalian cell survival. (1972) (67)
- Studies on auromomycin. (1979) (67)
- A NEW ANTIBIOTIC, KASUGSMYCIN. (1965) (64)
- Properties and specificity of binding sites for the immunomodulator bestatin on the surface of mammalian cells. (1982) (64)
- Chemistry of bleomycin. XXII. Interaction of bleomycin with nucleic acids, preferential binding to guanine base and electrostatic effect of the terminal amine. (1978) (64)
- Biological studies on bleomycin A. (1967) (64)
- Suppression of tissue graft rejection by spergualin. (1985) (64)
- Structure of antipain, a new Sakaguchi-positive product of streptomyces. (1972) (63)
- Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa. (1968) (62)
- Immunosuppressive activities of 15-deoxyspergualin in animals. (1987) (62)
- Phosphorylation and inactivation of aminoglycosidic antibiotics by E. coli carrying R factor. (1968) (62)
- The structure of chymostatin, a chymotrypsin inhibitor. (1973) (61)
- Decrease of melting temperature and single strand scission of DNA by bleomycin in the presence of hydrogen peroxide. (1969) (61)
- Inhibition of DNA-dependent RNA polymerase reaction of Escherichia coli by an antimicrobial antibiotic, streptovaricin. (1968) (60)
- Isolation and structure of a new antibiotic, indolizomycin, produced by a strain SK2-52 obtained by interspecies fusion treatment. (1984) (60)
- Biological studies on individual bleomycins. (1968) (60)
- Proteinase inhibitors : medical and biological aspects (1983) (59)
- Modes of action of phleomycin, bleomycin and formycin on HeLa S3 cells in synchronized culture. (1967) (59)
- Production of nineteen anthracyclic compounds by Streptomyces galilaeus MA144-M1. (1977) (59)
- The effect of bleomycin on SV40 DNA: characteristics of bleomycin action which produces a single scission in a superhelical form of SV40 DNA. (1973) (58)
- Kinetic studies of tyrosine kinase inhibition by erbstatin. (1987) (58)
- Structure and action of bleomycin. (1976) (58)
- REACTION OF BLEOMYCIN WITH DNA (1971) (58)
- Structures and Syntheses of Leupeptins Pr-LL and Ac-LL (1969) (57)
- Studies on adenylylstreptomycin, a product of streptomycin inactivation by E. coli carrying the R-factor. (1968) (57)
- Synthetic analogues and biosynthetic intermediates of bleomycin. Metal-binding, dioxygen interaction, and implication for the role of functional groups in bleomycin action mechanism. (1983) (57)
- Letter: Kanamycin phosphotransferase. I. Mechanism of cross resistance between kanamycin and lividomycin. (1973) (57)
- Mode of inhibition of coformycin on adenosine deaminase. (1967) (56)
- Identification and properties of the cell membrane bound leucine aminopeptidase interacting with the potential immunostimulant and chemotherapeutic agent bestatin. (1983) (56)
- Intracellular reduction of the cupric ion of bleomycin copper complex and transfer of the cuprous ion to a cellular protein. (1977) (56)
- Isolation and structure of a beta-lactamase inhibitor from Streptomyces. (1977) (55)
- Isolation and characterization of terpentecin, a new antitumor antibiotic. (1985) (54)
- Biosynthesis of napyradiomycins. (1987) (54)
- Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor. (1968) (54)
- Inhibition of dopamine beta-hydroxylase by 5-alkylpicolinic acid and their hypotensive effects. (1969) (54)
- REDUCTIVE CLEAVAGE OF ANTHRA-CYCLINE GLYCOSIDES BY MICROSOMAL NADPH-CYTOCHROME C REDUCTASE (1977) (53)
- Influence of formycin B on polyadenosine diphosphoribose synthesis in vitro and in vivo. (1975) (52)
- Synthesis of 3'-deoxykanamycin effective against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa. (1971) (52)
- The structure of a glyoxalase I inhibitor and its chemical reactivity with SH-compounds. (1975) (52)
- Isolation and characterization of plasmid DNAs in Actinomycetes. (1980) (51)
- New anthracycline antibiotic aclacinomycin A: experimental studies and correlations with clinical trials. (1981) (51)
- Activation of DNA metabolism in T-cells by bestatin. (1979) (51)
- Biological Sciences: Adrenal Tyrosine Hydroxylase and Dopamine β-Hydroxylase in Spontaneously Hypertensive Rats (1971) (50)
- Isolation and properties of valanimycin, a new azoxy antibiotic. (1986) (50)
- Arphamenines A and B, new inhibitors of aminopeptidase B, produced by bacteria. (1983) (50)
- Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activity. (1986) (50)
- Baumycins, new antitumor antibiotics related to daunomycin. (1977) (49)
- A new antibiotic, calvatic acid. (1975) (48)
- A new antitumor antibiotic, bactobolin produced by Pseudomonas. (1979) (48)
- KANAMYCIN: ITS DISCOVERY (1958) (48)
- Marinactan, antitumor polysaccharide produced by marine bacteria. (1983) (48)
- An enzyme inhibitor, panosialin, produced by Streptomyces. II. Chemistry of panosialin, 5-alkylbenzene-1,3-disulfates. (1971) (47)
- Effect of bestatin on syngeneic tumors in mice. (1984) (47)
- KD16-U1, a new metabolite of Streptomyces: isolation and structural studies. (1974) (47)
- Small molecular immunomodifiers of microbial origin : fundamental and clinical studies of bestatin (1981) (47)
- The distribution of 3H-bleomycin in mouse tissue. (1968) (46)
- A NEW ANTIBIOTIC, FORMYCIN. (1964) (46)
- Chemical studies on bleomycins. I. The acid hydrolysis products of bleomycin A2. (1968) (45)
- Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus. (1968) (44)
- Structures of pluramycin A and neopluramycin. (1977) (44)
- Antitumor activity of erbstatin, a tyrosine protein kinase inhibitor. (1987) (44)
- Total synthesis of bleomycin A21) (1982) (44)
- Blastogenic responses and the release of interleukins 1 and 2 by spleen cells obtained from rat skin allograft recipients administered with 15-deoxyspergualin. (1987) (44)
- Biological studies on the degradation products of 3-[(S)-1'-phenylethylamino]propylaminobleomycin: a novel analog (pepleomycin). (1979) (43)
- The chemical synthesis of bestatin. (1976) (43)
- DNA-bleomycin interaction: Nucleotide sequence-specific binding and cleavage of DNA by bleomycin (1984) (42)
- Isolation of isoflavones inhibiting DOPA decarboxylase from fungi and streptomyces. (1975) (42)
- A new microbial metabolite phosphoramidon (Isolation and structure) (1972) (42)
- Lipid peroxidation by bleomycin-iron complexes in vitro. (1985) (42)
- Enhancement of interleukin 1 and interleukin 2 releases by ubenimex. (1987) (42)
- The total synthesis of spergualin, an antitumor antibiotic. (1981) (42)
- Negamycin, a miscoding antibiotic with a unique structure. (1972) (42)
- Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. I. Glycosidation of various anthracyclinones by an aclacinomycin-negative mutant and biosynthesis of aclacinomycins from aklavinone. (1980) (42)
- Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunorubicin-producing microorganism. (1986) (42)
- Resistance mechanisms of kanamycin-, neomycin-, and streptomycin-producing streptomycetes to aminoglycoside antibiotics. (1981) (41)
- Antrimycin, a new peptide antibiotic. (1981) (41)
- Phosphorylation and inactivation of kanamycin by Pseudomonas aeruginosa. (1968) (41)
- Studies on Aminosugars. XXXII. Synthesis of 3′, 4′-Dideoxykanamycin B (1972) (41)
- Purification and properties of kanamycin-phosphorylating enzyme from Pseudomonas aeruginosa. (1969) (41)
- Mechanism of kasugamycin action on polypeptide synthesis. (1966) (41)
- Characterization of bleomycin action on DNA. (1975) (41)
- Inhibition of tyrosine protein kinase by synthetic erbstatin analogs. (1987) (41)
- Mechanism of action of phleomycin, a tumor-inhibitory antibiotic. (1963) (40)
- New antibiotic-producing streptomycetes, selected by antibiotic resistance as a marker. I. New antibiotic production generated by protoplast fusion treatment between Streptomyces griseus and S. tenjimariensis. (1985) (40)
- Microbial conversion of anthracyclinones to daunomycin by blocked mutants of Streptomyces coeruleorubidus. (1980) (40)
- Fundamental and clinical studies on new bleomycin analogs. (1978) (40)
- Biosynthetic studies of terpentecin. (1986) (40)
- Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes. (1982) (39)
- Studies on the mode of action of althiomycin. (1970) (39)
- New anthracyclines, feudomycins, produced by the mutant from Streptomyces coeruleorubidus ME130-A4. (1981) (39)
- Ebelactone, an inhibitor of esterase, produced by actinomycetes. (1980) (38)
- Effects of bleomycin A2 on deoxyribonuclease, DNA polymerase and ligase reactions. (1971) (38)
- Decilorubicin, a new anthracycline antibiotic. (1983) (38)
- Oxanosine, a novel nucleoside from actinomycetes. (1981) (38)
- Macromomycin, an inhibitor of the membrane function of tumor cells. (1972) (37)
- The molecular and crystal structure determination of bisanhydroalthiomycin by the x-ray diffraction method. (1974) (37)
- Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes. (1970) (37)
- Aminoglycoside 3'-phosphotransferases I and II in Pseudomonas aeruginosa. (1975) (37)
- Kasugamycin, a new antibiotic. (1965) (37)
- X-ray structure determination of (2S, 3R)-3-amino-2-hydroxy-4-phenylbutanoic acid, a new amino acid component of bestatin. (1976) (37)
- Structural basis of kanamycin for miscoding activity. (1967) (37)
- MICROBIAL CONVERSION OF ε-PYRROMYCINONE AND ε-ISORHODOMYCINONE TO 1-HYDROXY-13-DIHYDRODAUNOMYCIN AND N-FORMYL-1-HYDROXY-13-DIHYDRODAUNOMYCIN AND THEIR BIOACTIVITIES (1980) (36)
- Ribosomal resistance of an istamycin producer, Streptomyces tenjimariensis, to aminoglycoside antibiotics. (1981) (36)
- Studies on effects of forphenicinol on immune responses. (1982) (36)
- New antibiotic napyradiomycins A2 and B4 and stereochemistry of napyradiomycins. (1987) (36)
- Genetics and biochemical studies of chloramphenicol-nonproducing mutants of Streptomyces venezuelae carrying plasmid. (1979) (36)
- The structure of baumycins A1, A2, B1, B2, C1 and C2. (1977) (36)
- SYNTHESES OF (S)-4-AMINO-2-HYDROXYBUTYRYL DERIVATIVES OF 3', 4'-DIDEOXYKANAMYCIN B AND THEIR ANTIBACTERIAL ACTIVITIES (1973) (35)
- Inhibition of tyrosine hydroxylase by aquayamycin. (1968) (35)
- Effects of hydrolase inhibitors on fertilization of sea urchins: I. Protease inhibitors (1979) (35)
- Effect of diketocoriolin B on antibody formation. (1972) (34)
- Diketocoriolin B, an active derivative of coriolin B produced by Coriolus consors. (1971) (34)
- Biological studies on kanamycin. (1957) (34)
- Chemistry of bleomycin. XVI epi-bleomycin. (1976) (33)
- Syntheses of 6'-N-methyl-kanamycin and 3',4'-dideoxy-6'-N-methylkanamycin B active against resistant strains having 6'-N-acetylating enzymes. (1972) (33)
- Foroxymithine, a new inhibitor of angiotensin-converting enzyme, produced by actinomycetes. (1985) (33)
- A new antibiotic, pyridomycin. (1953) (33)
- Biosyntheses of new bleomycins. (1974) (33)
- Biological properties of new acyl derivatives of tylosin. (1980) (33)
- SYNTHESIS OF 3'-DEOXYKANAMYCIN B (1973) (33)
- The structure of SS-228Y, an antibiotic from Chainia Sp. (1975) (33)
- Synthesis and antitumor activity of spergualin analogues. III. Novel method for synthesis of optically active 15-deoxyspergualin and 15-deoxy-11-O-methylspergualin. (1987) (33)
- Mechanism of action of diketocoriolin B. (1973) (33)
- Structure-activity relationships of anthracyclines relative to cytotoxicity and effects on macromolecular synthesis in L1210 leukemia cells. (1981) (32)
- Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by snythetic polynucleotide. (1970) (32)
- The structure of antrimycin. (1981) (32)
- Isolation and characterization of lividomycin A inactivated by Pseudomonas aeruginosa and Escherichia coli carrying R factor. (1972) (32)
- Letter: Absolute configuration of coriolin, a sesquiterpene antibiotic from Coriolus consors. (1974) (32)
- Chemical studies on kasugamycin. V. The structure of kasugamycin. (1966) (32)
- Kinetics of the reaction of bleomycin-Fe(II)-O2 complex with DNA. (1980) (32)
- CHEMISTRY OF BLEOMYGIN. III THE SUGAR MOIETIES OF BLEOMYGIN A2 (1969) (32)
- The chemistry of bleomycin. II the molecular and crystal structure of a sulfur-containing chromophoric amino acid (1968) (32)
- Immunosuppression induced with cell-free fluid of Ehrlich carcinoma ascites and its fractions. (1973) (32)
- ANTIMICROBIAL ACTIVITY OF KASUGAMYCIN. (1965) (31)
- TWO β-LACTAMASE INHIBITORS PRODUCED BY A STREPTOMYCES (1973) (31)
- NEW COMPONENTS OF BLEOMYCIN (1973) (31)
- Minor congeners of antrimycin: application of secondary ion mass spectrometry (SIMS) to structure determination. (1982) (31)
- Studies on inactivation of kanamycin and resistances of E. coli. (1967) (30)
- Synthesis of the pyrimidine moiety of bleomycin (1980) (30)
- Elimination of the ability of a kanamycin-producing strain to biosynthesize deoxystreptamine moiety by acriflavine. (1977) (30)
- Mechanisms of Resistance to Aminoglycoside Antibiotics (1982) (30)
- Synthesis of 4-demethoxy-11-deoxy-analogs of daunomycin and adriamycin. (1980) (30)
- A new antibiotic, althiomycin. (1957) (30)
- Pharmacokinetics of macrolides, lincosamides and streptogramins. (1985) (30)
- Synthesis of 3'.4'-dideoxyneamine active aginst kanamycin-resistant E. coli and P. aeruginosa. (1971) (30)
- Influence of coformycin on the cytostatic activity of 9-beta-D-arabinofuranosyladenine and adenosine in mouse L5178y cells. (1978) (30)
- Immunosuppressive activity of 15-deoxyspergualin and its effect on skin allografts in rats. (1987) (30)
- Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions. (1974) (30)
- Sarkomycin, an anti-tumor substance produced by streptomyces. (1953) (30)
- Advances in Bleomycin Studies (1979) (30)
- Mechanism of resistance to aminoglycoside antibiotics in nebramycin-producing Streptomyces tenebrarius. (1982) (30)
- The bleomycins: Antitumor copper-binding antibiotics (1980) (29)
- Isolation of lecanoric acid, an inhibitor of histidine decarboxylase from a fungus. (1974) (29)
- MECHANISM OF ACTION OF NEGAMYCIN IN ESCHERICHIA COLI K 12 (1970) (29)
- Total synthesis of deglyco-bleomycin A2 (1981) (29)
- Saphenamycin, a novel antibiotic from a strain of Streptomyces. (1982) (29)
- New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. I. Isolation and characterization of various blocked mutants. (1981) (29)
- Inhibition of initiation of DNA-dependent RNA synthesis by an antibiotic B44p. (1968) (29)
- Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation. (1980) (29)
- Production of novel antibiotic, dopsisamine, by a new subspecies of Nocardiopsis mutabilis with multiple antibiotic resistance. (1986) (29)
- Studies on formycin and formycin B in cells of Ehrlich carcinoma and E. coli. (1967) (29)
- A new microbial product, oudenone, inhibiting tyrosine hydroxylase. (1970) (28)
- Biosynthesis of leupeptin. (1978) (28)
- Structure determinations of enzymatically phosphorylated products of aminoglycosidic antibiotics by proton magnetic resonance. (1971) (28)
- Chemistry of bleomycin. V. Revised structure of an amine component of bleomycin A2. (1971) (28)
- Revised Structure and Stereochemistry of Coriolins (1971) (28)
- Inhibition of ligase reaction by bleomycin. (1971) (28)
- Siastatin B, a potent neuraminidase inhibitor: the total synthesis and absolute configuration (1988) (28)
- ACTIVITY OF BESTATIN: ENHANCEMENT OF IMMUNE RESPONSES AND ANTITUMOR EFFECT (1981) (28)
- Antitumor activity of spergualin, a novel antitumor antibiotic. (1986) (28)
- Biosynthesis of anthracycline antibiotics by Streptomyces galilaeus. II. Structure of new anthracycline antibiotics obtained by microbial glycosidation and biological activity. (1980) (27)
- Synthesis of antitumor-active 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone. (1987) (27)
- Glycocinnasperimicin D, a new member of glycocinnamolyspermidine antibiotic. (1985) (27)
- Relationship between antibiotic resistance and antibiotic productivity in actinomycetes which produce aminoglycoside antibiotics. (1983) (27)
- Binding of blasticidin S to ribosomes. (1970) (27)
- A high performance liquid chromatographic method of analysis of 4'-O-tetrahydropyranyladriamycin and their metabolites in biological samples. (1983) (26)
- Letter: Gentamicin acetyltransferase in Escherichia coli carrying R factor. (1973) (26)
- On a new antibiotic, griseolutein, produced by streptomyces. (1950) (26)
- [Preferential inhibition of the growth of Escherichia coli strains carrying episomes]. (1970) (26)
- New anthracycline antibiotics, rhodirubins. (1977) (26)
- Enhancement of antitumor effect of cytotoxic agents by bestatin. (1985) (26)
- Synthesis of azepinomycin and its beta-D-ribofuranoside. (1987) (26)
- Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. I. Taxonomy of the producing organism and isolation and biological properties of the antibiotics. (1986) (26)
- Nucleotide sequence of the streptomycinphosphotransferase and amidinotransferase genes from Streptomyces griseus. (1987) (26)
- Self-resistance of a Streptomyces which produces istamycins. (1981) (26)
- The structure determination of an enzymatic inactivation product of 3',4'-dideoxykanamycin B. (1971) (26)
- Negamycin inhibits termination of protein synthesis directed by phage f2 RNA in vitro. (1974) (26)
- New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides. (1981) (26)
- THE ABSOLUTE STRUCTURE OF ORYZOXYMYCIN (1974) (26)
- Biosynthesis of 2-deoxystreptamine. (1985) (26)
- Transition-metal binding site of bleomycin. A remarkably efficient dioxygen-activating molecule based on bleomycin-Fe(II) complex☆ (1986) (25)
- Letter: Chemistry of bleomycin. XII. Iso-bleomycin A2, product of carbamoyl group migration. (1973) (25)
- An antiviral substance, abikoviromycin, produced by Streptomyces species. (1951) (25)
- CHEMISTRY OF BLEOMYCIN. XI (1973) (25)
- ISOLATION OF A NEW ANTIBIOTIC SUBSTANCE, AUREOTHRICIN FROM A STRAIN OF STREPOMYCES (1948) (25)
- The structure of an epidermal growth factor-receptor kinase inhibitor, erbstatin. (1986) (25)
- SMALL MOLECULAR WEIGHT IMMUNOMODIFIERS PRODUCED BY MICROORGANISMS: THEIR SCREENING AND DISCOVERIES, AND THE GENETICS OF MICROBIAL SECONDARY METABOLITES (1981) (25)
- Isolation and Characterization of PDE-I and II, the Inhibitors of Cyclic Adenosine-3', 5'-monophosphate Phosphodiesterase (1978) (25)
- Potentiation of the cytostatic effect of bleomycin on L5178y mouse lymphoma cells by pepleomycin. (1983) (25)
- Studies on lignan lactone antitumor agents. II. Synthesis of N-alkylamino- and 2,6-dideoxy-2-aminoglycoside lignan variants related to podophyllotoxin. (1986) (25)
- Specific inhibition of the termination process of protein synthesis by negamycin. (1976) (24)
- Cytotoxicity of spergualin and amine oxidase activity in medium. (1985) (24)
- New antibiotics clazamycins A and B. (1979) (24)
- Induction of antitumor resistance to mouse leukemia L1210 by spergualins. (1986) (24)
- Studies on Aminosugars. XXIX. The Synthesis of 3′-O-Methylkanamycin (1972) (24)
- Response in macromolecular syntheses of mouse L cells to bleomycin, with special reference to cell-antibiotic interaction. (1973) (24)
- New morpholino anthracyclines, MX, MX2, and MY5. (1987) (24)
- Synthesis of butirosin B. (1972) (24)
- Metabolism of formycin and formycin B in vitro. (1968) (24)
- Chemistry of bleomycin. IV. The structure of amine component II of bleomycin A2. (1970) (24)
- STUDIES ON THE PREVENTIVE EFFECT OF KASUGAMYCIN ON RICE BLAST. (1965) (24)
- Cellular uptake and efflux and cytostatic activity of 4'-O-tetrahydropyranyladriamycin in adriamycin-sensitive and resistant tumor cell lines. (1984) (24)
- Biosynthesis of daunomycinone from aklavinone and epsilon-rhodomycinone. (1980) (24)
- R Factor-Mediated Aminoglycoside Antibiotic Resistance in Pseudomonas aeruginosa: a New Aminoglycoside 6′-N-Acetyltransferase (1975) (24)
- Antitumor effect of forphenicinol, a low molecular weight immunomodifier, on murine transplantable tumors and microbial infections. (1982) (24)
- Enzymatic conversion of aclacinomycin A to Y by a specific oxidoreductase in Streptomyces. (1979) (24)
- Isolation and characterization of bottromycins A2, B2, C2. (1967) (24)
- The structure of althiomycin. (1974) (24)
- The crystal and molecular structures of oxoformycin B and formycin, B (1976) (24)
- Transition-metal binding site of bleomycin. A synthetic analogue equivalent to bleomycin in activating molecular oxygen (1986) (24)
- Letter: Chemical cleavage of bleomycin to bleomycinic acid and synthesis of new bleomycins. (1973) (24)
- Synthesis of forphenicinol and forphenicine. (1982) (23)
- The crystal structure of kanamycin. (1968) (23)
- The X-ray structure determination of oxanosine. (1981) (23)
- Studies on Aminosugars. XXX. The Synthesis of 3′-Deoxykanamycin (1972) (23)
- Suppression of humoral immunity in dogs by 15-deoxyspergualin. (1987) (23)
- New anthracycline antibiotic, 2-hydroxyaclacinomycin A. (1981) (23)
- PREPARATION OF BLEOMYGINIG ACID: HYDROLYSIS OF BLEOMFYGIN B2 BY A FUSARIUM AGYLAGMATINE AMIDOHYDROLASE (1973) (23)
- Chemistry of bleomycin. XVII. Chemical proof for the beta-lactam of bleomycin. (1977) (23)
- Biochemical studies on bactobolin in relation to actinobolin. (1981) (23)
- INHIBITION OF DOPAMINE β-HYDROXYLASE BY AQUAYAMYCIN (1968) (23)
- 6'-N-acetylation of 3',4'-dideoxykanamycin B by an enzyme in a resistant strain of Pseudomonas aeruginosa. (1972) (23)
- Screening of small molecular microbial products modulating immune responses and bestatin. (1980) (23)
- SEPARATION OF PHLEOMYCIN COMPONENTS AND THEIR PROPERTIES. (1964) (22)
- A new microbial metabolite, sphydrofuran. I. Isolation and the structure of a hydrolysis product. (1971) (22)
- Reticulol, an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase. (1975) (22)
- Effects of several tumor-inhibitory antibiotics on immunological responses. (1969) (22)
- Studies on kanamycin. (1957) (22)
- New anthracyclinone metabolites from two blocked mutants of Streptomyces galilaeus MA144-M1. (1982) (22)
- Bleomycin inhibition of DNA synthesis in isolated enzyme systems and in intact cell systems. (1975) (22)
- Liblomycin, a new analogue of bleomycin. (1987) (22)
- Inhibition of RNA and DNA polymerase reactions by pluramycin A. (1965) (22)
- New anthracyclic antibiotics roseorubicins A and B. (1979) (22)
- S-2,3-dicarboxy-aziridine, a new metabolite from a Streptomyces. (1975) (22)
- Biosynthesis of aklavinone and aclacinomycins. (1981) (22)
- Oudenone, a novel tyrosine hydroxylase inhibitor from microbial origin. (1971) (22)
- Synthetic studies on pyrrolizidine alkaloid antitumor agents. Enantioselective synthesis of retronecine and its enantiomer from D-glucose (1985) (22)
- Enhancement of immune responses and possible inhibition of suppressor cells by aclacinomycin A. (1981) (22)
- CHEMICAL STUDIES ON BLEOMYCINS. I (1968) (22)
- Natural and artificial bleomycins: chemistry and antitumor activities. (1971) (21)
- A new antibiotic, phleomycin. (1956) (21)
- The chemistry of bleomycin. 8. The structure of the sugar moiety of bleomycin A 2 . (1972) (21)
- Aminoglycoside 3'-phosphotransferase III, a new phosphotransferase. Resistance mechanism. (1975) (21)
- Stereoselective synthesis of (2s,3s,4r)-4-amino-3-hydroxy-2-methyl-pentanoic acid, an amino acid constituent of bleomycin, by aldold condensation)☆ (1982) (21)
- The structure of a new antibiotic, terpentecin. (1985) (21)
- Formycin B and its relation to formycin. (1965) (21)
- Prolongation of rat heart allograft survival by 15-deoxyspergualin. (1987) (21)
- MINOSAMINOMYCIN, A NEW ANTIBIOTIC CONTAINING MYO-INOSAMINE (1974) (21)
- New antibiotics, ilamycins. (1962) (21)
- Recent advances in chemistry and biochemistry of antibiotics (1964) (21)
- Isolation, characterization and structural elucidation of new amino acids from bottromycin A. (1965) (21)
- The total synthesis of kasugamycin. (1972) (21)
- Histargin, a new inhibitor of carboxypeptidase B, produced by actinomycetes. (1984) (21)
- Structure and Chemical Synthesis of Amastatin (1979) (21)
- Syntheses of 23-dialkylamino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide effective against gram-negative bacteria. (1982) (21)
- SYNTHESES AND ANTITUMOR ACTIVITIES OF 7-O-(2, 6-DIDEOXY-2-FLUORO-α-L-TALOPYRANOSYL)-DAUNOMYCINONE AND -ADRIAMYCINONE (1986) (20)
- Antitumor activity of new morpholino anthracyclines. (1988) (20)
- Ribocitrin, a new inhibitor of dextransucrase. (1981) (20)
- Studies on Aminosugars. XXXV. Syntheses of 3′,4′-Dideoxyneamine and 3′- and 4′-O-Methylneamines (1973) (20)
- Decilonitrose and 4-O-succinyl-L-diginose, sugar components of decilorubicin. (1983) (20)
- Transition-metal binding site of bleomycin. A synthetic analogue capable of binding Fe(II) to yield an oxygen-sensitive complex (1981) (20)
- Transfer of the leupeptin-producing ability of the strain, Streptomyces roseus MA839-A1, by conjugation. (1978) (20)
- Antitumor effect of bactobolin and its influence on mouse immune system and hematopoietic cells. (1980) (20)
- Structure of pyridindolol, inhibitor of beta-galactosidase. (1975) (20)
- Mode of action of oxanosine, a novel nucleoside antibiotic. (1982) (20)
- The revised structure of bottromycin A2. (1976) (20)
- Inhibition of polypeptide synthesis by kasugamycin, an aminoglycosidic antibiotic. (1966) (20)
- The Structure of MS-3: A Glyoxalase I Inhibitor Produced by a Mushroom (1975) (20)
- An evaluation of taxonomic criteria in streptomycetes on the basis of deoxyribonucleic acid homology. (1972) (20)
- New antibiotic-producing streptomycetes, selected by antibiotic resistance as a marker. II. Features of a new antibiotic-producing clone obtained after fusion treatment. (1985) (20)
- Immunochemical identification of the cell surface bound leucine aminopeptidase, the target enzyme for the immunostimulant bestatin. (1983) (20)
- CHEMISTRY OF BLEOMYCIN. XII (1973) (20)
- Synthesis and antitumor activity of spergualin analogues. II. Chemical modification of the spermidine moiety. (1987) (20)
- Trisarubicinol, new antitumor anthracycline antibiotic. (1981) (20)
- The structure of decilorubicin. (1984) (20)
- Multiple resistance to aminoglycoside antibiotics in actinomycetes. (1983) (20)
- Immunomodulating properties of bestatin in cancer patients. A phase II trial. (1986) (19)
- Synthetic study towards man-designed bleomycins. Synthesis of a DNA cleaving molecule based on bleomycin (1986) (19)
- The effect of ubenimex on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumor in rats. (1986) (19)
- Structure of minosaminomycin. (1975) (19)
- Chemistry of bleomycin. XXIV. Deadmido bleomycin from viewpoint of metal coordination and oxygen activation. (1979) (19)
- A new anthracycline metabolite D788-1 (10-carboxy-13-deoxocarminomycin) in daunorubicin beer. (1986) (19)
- Synthesis of 4'-deoxymycaminosyl tylonolide. (1981) (19)
- Action of ubenimex on aminopeptidase activities in spleen cells and peritoneal macrophages from mice. (1987) (19)
- A synthesis of 3',4'-dideoxykanamycin B. (1976) (19)
- Isolation and characterization of a new antibiotic, dioxapyrrolomycin, related to pyrrolomycins. (1987) (19)
- Effect of 15-deoxyspergualin on graft-v-host disease in mice. (1987) (19)
- Leupeptin and antipain. Strong competitive inhibitors of sperm acrosomal proteinase (boar acrosin) and kallikreins from porcine organs (pancreas, submand. glands, urine). (1973) (19)
- The crystal structure of formycin hydrobromide monohydrate (1974) (19)
- Different Sensitivity to Bleomycin-Induced Pulmonary Fibrosis among Various Strains of Mice (1987) (19)
- Antitumor anthracycline antibiotics, aclacinomycin A and analogues. I. Taxonomy, production, isolation and physicochemical properties. (1979) (19)
- Mazethramycin, a new member of anthramycin group antibiotics. (1980) (18)
- Studies on the biosynthesis of 3-amino-3-deoxy-D-glucose. (1968) (18)
- Chemistry of enzyme inhibitors of microbial origin (1973) (18)
- Distribution of chloramphenicol acetyltransferase and chloramphenicol-3-acetate esterase among Streptomyces and Corynebacterium. (1977) (18)
- The total synthesis of kasugamycin. (1968) (18)
- Microbial conversion of daunomycin, carminomycin I and feudomycin A to adriamycin. (1981) (18)
- Arglecin, a new microbial metabolite isolation and chemical structure. (1971) (18)
- Synthesis of 2′,3′-Dideoxy-2′-Fluorokanamycin A (1985) (18)
- Studies on antibiotic actinomycetes. IX. On Streptomyces producing a new antifungal substance mediocidin and antifungal substances of fungicidin-rimocidin-chromin group, eurocidin group and trichomycin-ascosin-candicidin group. (1954) (18)
- Synthesis of lividomycin A 5''-phosphate, an enzymatically inactivated lividomycin A. (1972) (18)
- Syntheses of 3-fluoro derivatives of sporaricin A, 3-epifluoro-, 3-fluoror, and 3,3-difluoro-3-demethoxysporaricin A. (1982) (18)
- SYNTHESIS OF 4-AMINO-3 HYDROXY-6-METHYLHEPTANOIG ACID, AN AMINE COMPONENT OF PEPSTATIN (1973) (18)
- Synthesis of 3',4'-dideoxy and 3',4',5''-trideoxyribostamycin active against kanamycin-resistant E. coli and P. aeruginosa. (1972) (18)
- New anthracycline derivatives from betaclamycin A. (1984) (18)
- Reductive cleavage of anthracycline glycosides by microsomal NADPH-cytochrome C reductase. (1977) (18)
- Structure-activity relationships among negamycin analogs. (1976) (18)
- Blastmycin, a new antibiotic from Streptomyces sp. (1957) (18)
- CLASSIFICATION OF ANTIBIOTIC STRAINS OF STREPTOMYCES AND THEIR ANTIBIOTIC SUBSTANCES ON THE BASIS OF THEIR ANTIBACTERIAL SPECTRA (1948) (17)
- Letter: X-ray structure determination of 4-amino-3-hydroxy-6-methylheptanoic acid, an amine component of pepstatin. (1973) (17)
- Variotin, a new antifungal antibiotic, produced by Paecilomyces varioti Bainier var. antibioticus. (1959) (17)
- A -lactamase of Escherichia coli. (1972) (17)
- Chemistry of bleomycin. VI. Selective cleavage of bleomycin A 2 by N-bromosuccinimide. (1972) (17)
- Studies on the reconstitution of macromomycin a d auromomycin from the chromophore and protein moieties. (1982) (17)
- Recent studies on bleomycin. (1977) (17)
- Dopastin, an inhibitor of dopamine -hydroxylase. (1972) (17)
- Application of high-voltage paper electrophoresis for separation and identification of antibiotics. (1969) (17)
- PHARMACOLOGY OF KASUGAMYCIN AND THE EFFECT ON PSEUDOMONAS INFECTION. (1965) (17)
- Synthesis of cleonine, amino(1-hydroxycyclopropyl)acetic acid, a novel amino acid contained in cleomycin (1980) (17)
- Effects of enzyme inhibitors in inhibiting the growth and inducing the differentiation of human promyelocytic leukemia cells, HL-60. (1986) (17)
- The antiproliferative action of deoxyspergualin is different from that induced by amine oxidase. (1988) (17)
- Regio- and stereo-specific synthesis of threo-3-amino-2-hydroxy-acids, novel amino-acids contained in aminopeptidase inhibitors of microbial origin. (1980) (17)
- Studies on antitumor activity, antimicrobial activity and toxicity of phleomycin. (1966) (17)
- A degradation product of the chromophore of auromomycin. (1983) (17)
- New antitumor antibiotics, ditrisarubicins A, B and C. (1983) (17)
- Inactivation of 3',4'-dideoxykanamycin B by an enzyme solution of resistant E. coli and isolation of 3',4'-dideoxykanamycin B 2''-guanylate and 2''-inosinate. (1972) (17)
- Biosynthesis of leupeptin. II Purification and properties of leupeptin acid synthetase. (1979) (17)
- Production of tertiomycin (a new antibiotic substance), azomycin and eurocidin by S. eurocidicus. (1955) (17)
- Basidalin, a new antibiotic from basidiomycetes. (1983) (17)
- Transformation of formycin to formycin B and their biological activities. (1965) (17)
- Antitumor activities of (2"R)-4'-O-tetrahydropyranyl-adriamycin (THP) and its combination with other antitumor agents on murine tumors. (1985) (17)
- Mechanism of action of kasugamycin. (1965) (16)
- Synthesis of 3'-deoxy-3'-fluorokanamycins A and B active against resistant bacteria. (1985) (16)
- Dotriacolide, a new beta-lactamase inhibitor. (1981) (16)
- Small molecular microbial products enhancing immune response. (1978) (16)
- Enhancement of graft-versus-host reaction and delayed cutaneous hypersensitivity in mice by ubenimex. (1986) (16)
- Sarkomycin, and anti-cancer substance produced by Stroptomyces. (1954) (16)
- Physical characterization of plasmids from Streptomyces kasugaensis MB273. (1981) (16)
- SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONS OF BESTATIN ANALOGS, INHIBITORS OF AMINOPEPTIDASE B (1977) (16)
- Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. (1981) (16)
- DNA strand scission of methanol-extracted chromophores of macromomycin and auromomycin. (1982) (16)
- New macrolide antibiotics produced by mutants from Streptomyces fradiae NRRL 2702. (1982) (16)
- Adrenal tyrosine hydroxylase and dopamine beta-hydroxylase in spontaneously hypertensive rats. (1971) (16)
- SYNTHESIS OF 3'', 4''-DIDEOXYBUTIROSIN B (1973) (16)
- Biosynthesis of the formycin family. (1971) (16)
- Synthesis of 3′-Deoxykanamycin B (Tobramycin) (1976) (16)
- Combimicins, new kanamycin derivatives bioconverted by some Micromonosporas. (1981) (16)
- Biosynthesis of leupeptin. III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine. (1980) (16)
- Studies of tylosin derivatives effective against macrolide-resistant strains: synthesis and structure-activity relationships. (1982) (16)
- Isolation of paromamine inactivated by Pseudomonas aeruginosa. (1968) (16)
- Effective synthesis of erbstatin and its analogs. (1987) (16)
- Mode of action of enomycin, an antitumor antibiotic of high molecular weight. I. Inhibition of protein synthesis. (1967) (16)
- On a new antifungal substance, mediocidin, and other antifungal substances of Streptomyces with three characteristic absorption maxima. (1954) (15)
- Purification of aminoglycoside 3'-phosphotransferase II. (1976) (15)
- Dopamine -hydroxylase inhibitor produced by Gloeophyllum striatum and its identity with oosponol. (1972) (15)
- An improved total synthesis of bleomycin. (1983) (15)
- D-beta-lysylmethanediamine, a new biogenetic amine produced by a Streptomyces. (1986) (15)
- Macarbomycin, an inhibitor of peptidoglycan synthesis. (1972) (15)
- Syntheses and properties of the 6"-deoxy or 4",6"-dideoxy derivatives of the kanamycin antibiotics. (1980) (15)
- Synthesis and antitumor activities of 14-O-acyl derivatives of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)adriamycinone. (1988) (15)
- STREPTOVARICIN- AND RIFAMPIGIN-RESISTANGE OF RNA POLYMERASE IN A RESISTANT CLONE OF ESCHERICHIA COLI B (1968) (15)
- Structure studies on kanamycin. (1958) (15)
- Chemistry of bleomycin. VII. Synthesis of -amino- -(4-amino-6-carboxy-5-methylpyrimidin-2-yl)-propionic acid, an amine component of bleomycin. (1972) (15)
- Increased sensitivity to oxanosine, a novel nucleoside antibiotic, of rat kidney cells upon expression of the integrated viral src gene. (1985) (15)
- Specificity of transport of bleomycin and cobalt-bleomycin in L5178Y cells. (1982) (15)
- 3-epi-deoxynegamycin and leucyl-3-epi-deoxynegamycin produced by Streptomyces. (1977) (15)
- 8''-Hydroxypactamycin and 7-deoxypactamycin, new members of the pactamycin group. (1986) (15)
- Cylinder plate method of testing the anti-cell effect; studies on antitumor substances produced by Actinomycetes. XII. (1956) (15)
- Relationship between enhancement of morphine analgesia and inhibition of enkephalinase by 2S, 3R 3-amino-2-hydroxy-4-phenylbutanoic acid derivatives. (1982) (15)
- SYNTHESIS OF 3'-DEOXYRIBOSTAMYCIN (1973) (15)
- The biosynthesis of pyridomycin. I. (1968) (15)
- Bottromycin A1, A2 and their structures. (1966) (15)
- Synthesis of 3'-deoxybutirosin B. (1975) (15)
- Aminoglycoside 6'-N-acetyl-transferase of Pseudomonas aeruginosa: structural requirements of substrate. (1975) (15)
- REVISED STRUCTURE FOR ARGLEGIN (1972) (14)
- Chemistry of bleomycin. XXVII. Cleomycin, a new family of bleomycin-phleomycin group. (1980) (14)
- Synthesis of a Lividomycin B Analogue, 5-O-[3-O-(2-Amino-2-deoxy-α-D-grlucopyranosyl)-β-D-ribofuranosyl]-3′-deoxyparomamine (1977) (14)
- Studies of the mechanism of action of diketocoriolin B to enhance antibody formation. (1981) (14)
- A tryptophan hydroxylase inhibitor produced by a streptomycete: 2,5-dihydro-L-phenylalanine. (1977) (14)
- Syntheses of corliolin, 1-deoxy-1-ketocoriolin and 1,8-dideoxy-1,8-diketocoriolin from coriolin B. (1980) (14)
- Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. (1981) (14)
- Factors Affecting Infection of Protoplasts with Deoxyribonucleic Acid of Actinophage PK-66 (1968) (14)
- Studies on lignan lactone antitumor agents. I. Synthesis of aminoglycosidic lignan variants related to podophyllotoxin. (1986) (14)
- PHENOMYCIN, TOXIGITY AND DISTRIBUTION (1971) (14)
- Bacillus cereus beta-lactamase. Reaction with N-bromosuccinimide and the properties of the product. (1975) (14)
- Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)-3',4'-dideoxyneamine. (1973) (14)
- Reaction of bleomycin with DNA. Strand scission of DNA in the absence of sulfhydryl or peroxide compounds. (1971) (14)
- A new antitumor substance, pluramycin; studies on antitumor substances produced by Actinomycetes. XI. (1956) (14)
- Synthesis of 3'-deoxy-3'-fluorokanamycin A and 3',4'-dideoxy-3'-fluorokanamycin A. (1991) (14)
- Studies on biosynthesis of kasugamycin. V. Biosynthesis of the amidine group. (1968) (14)
- Synthetic studies on an antitumor antibiotic, bleomycin. XIV. The synthesis of Boc-pyrimidoblamic acid. (1985) (14)
- Current status of Japanese studies with the new anthracycline antibiotic aclacinomycin A. (1980) (14)
- The structure of kasugamycin hydrobromide by x-ray crystallographic analysis. (1966) (14)
- Chapter 23 – NEW ANALOGS AND DERIVATIVES OF BLEOMYCIN (1985) (14)
- Biochemical activities of the derivatives of dehydrodicaffeic acid dilactone. (1978) (14)
- New potent anthracyclines, barminomycins I and II. (1988) (14)
- Pharmacological action of FD-008, a new dopamine beta-hydroxylase inhibitor. I. Effects on blood pressure in rats and dogs. (1975) (14)
- Structure of a neothramycin-2'-deoxyguanosine adduct. (1981) (14)
- Studies on enomycin, a new antitumor substance (1963) (14)
- HYDROXYPEPSTATIN, A NEW PEPSTATIN PRODUCED BY STREPTOMYCES (1973) (14)
- In situ inhibition of tyrosine protein kinase by erbstatin. (1987) (14)
- Protease inhibitors produced by microorganisms. (1977) (14)
- CHEMISTRY OF BLEOMYGIN. IV (1970) (14)
- A facile total synthesis of oxanosine, a novel nucleoside antibiotic (1983) (14)
- Isolation and structures of istamycin components (1982) (14)
- Monazomycin, a new antibiotic produced by a Streptomyces. (1963) (14)
- Activity of ribosomes from kanamycin-resistant E. coli. (1964) (14)
- The structure of arphamenines A and B. (1983) (14)
- Chemical modification of 5,3',4'-trideoxykanamycin B. (1981) (13)
- CHEMISTRY OF BLEOMYCIN. VII (1972) (13)
- Synthesis of Butirosin B and Its 3′,4′-Dideoxy Derivative (1974) (13)
- Vanoxonin, a new inhibitor of thymidylate synthetase. (1983) (13)
- New anthracycline antibiotics obtained by microbial glycosidation of beta-isorhodomycinone and alpha 2-rhodomycinone. (1984) (13)
- The structure of bottromycin A2, a new component of bottromycins. (1966) (13)
- Studies on anti-tumor substances produced by microorganisms. III. On sarkomycin produced by a strain resembling to Streptomyces erythrochromogenes. (1953) (13)
- Studies on Aminosugars. XXXVI. Syntheses of 3′,4′-Dideoxy-and 3′,4′,5″-Trideoxyribostamycin (1973) (13)
- Kinetic studies on the inhibition of (Na+++K+)-ATPase by diketocoriolin B. (1973) (13)
- Inhibition of protein synthesis by bottromycin A2 and its hydrazide. (1966) (13)
- Immunological studies of aminoglycoside 3'-phosphotransferases. (1976) (13)
- The chemistry of pyridomycin. (1968) (13)
- Experimental studies on aclacinomycin. (1985) (13)
- Further studies on the effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine. (1977) (13)
- The activity of 4''-acylated tylosin derivatives against macrolide-resistant gram-positive bacteria. (1979) (13)
- Suppression of experimental allergic encephalomyelitis in guinea pigs by spergualin and 15-deoxyspergualin. (1987) (13)
- Inhibition by kasugamycin of protein synthesis in Piricularia oryzae. (1968) (13)
- 7 – Low-molecular-weight Enzyme Inhibitors and Immunomodifiers (1988) (13)
- 3'-Deoxyamikacin and 3',4'-dideoxyamikacin and their antibacterial activities. (1979) (13)
- Localization of kanamycin sensitivity in the 23S core of 30S ribosomes of E. coli. (1968) (13)
- Syntheses of 2',3'-dideoxykanamycin A, 2',3'-dideoxyamikacin and related substances (1987) (12)
- The structure of spinamycin. (1968) (12)
- Studies on aminoglycoside antibiotics: enzymic mechanism of resistance and genetics. (1979) (12)
- Studies on biosynthesis of kasugamycin. 3. Biosynthesis of the d-inositol moiety. (1968) (12)
- Synthesis of isocoformycin, an adenosine deaminase inhibitor of synthetic origin. (1979) (12)
- Letter: Syntheses of isoseryl derivatives of kanamycins and their antibacterial activities. (1974) (12)
- 2"-N-formimidoylistamycin A and B produced by Streptomyces tenjimariensis. (1982) (12)
- Reversible binding of macromomycin, a macromolecular eptide antibiotic, to cell membranes. (1971) (12)
- Electrochemical and ESR studies on Cu(II) complexes of bleomycin and its related compounds. (1981) (12)
- Structure of griseolutein A. (1959) (12)
- Studies on biosynthesis of kasugamycin. I. Biosynthesis of kasugamycin and the kasugamine moiety. (1968) (12)
- SYNERGISM OF D-4-AMINO-3-ISOXAZOLIDONE AND O-CARBAMYL-D-SERINE. (1964) (12)
- The generation of additional antibiotic resistance by protoplast regeneration of a Streptomyces griseus strain. (1985) (12)
- LEUCYLNEGAMYCIN, AN ANTIBIOTIC FROM NEGAMYCIN-PRODUCING STREPTOMYCES (1971) (12)
- Synthesis of (14R)- and (14S)-14-De(hydroxymethyl)-14-hydroxymycaminosyl Tylonolides (1987) (12)
- Synthesis and Structure-activity Relationships of Amastatin Analogues, Inhibitors of Aminopeptidase A (1982) (12)
- Studies on mikamycin B. (1959) (12)
- Studies on dienomycins. II. Chemical structures of dienomycins A, B and C. (1970) (12)
- Antitumor cells found in tumor-bearing mice given ubenimex. (1987) (12)
- 3'-deamino-3'-morpholino derivatives of daunomycin, adriamycin and carminomycin. (1982) (12)
- Affinity labeling of an Escherichia coli β-lactamase (1973) (12)
- ISOLATION AND CHARACTERIZATION OF BOTTROMYCINS A AND B. (1965) (11)
- Inhibition of nucleic acid biosynthesis in cell-free systems of Escherichia coli B by pluramycin. (1970) (11)
- Effect of spergualin in autoimmune disease mice. (1987) (11)
- Effects of spergualin and 15-deoxyspergualin on the development of graft-versus-host disease in mice. (1987) (11)
- DNA structures required for bleomycin binding. (1978) (11)
- Effect of desdanine on nucleoside diphosphate kinase and pyruvate kinase of Escherichia coli. (1975) (11)
- Total synthesis of the disaccharide of bleomycin, 2-0-(α-D-mannopyranosyl)-L-gulopyranose (1981) (11)
- A new synthesis of deglyco-bleomycin A2 aiming at the total synthesis of bleomycin (1982) (11)
- Antiviral effect of formycin derivatives. (1967) (11)
- BIOSYNTHESIS OF KASUGAMYCIN. II (1968) (11)
- Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus. (1981) (11)
- A new destomycin-family antibiotic produced by Saccharopolyspora hirsuta. (1985) (11)
- Inhibition of dopamine beta-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo. (1970) (11)
- Relationship Between Sex-Pili Formation and Macarbomycin Sensitivity in Escherichia coli (1971) (11)
- Studies on new aminoglycoside antibiotics, istamycins, from an actinomycete isolated from a marine environment. II. Possible involvement of plasmid in istamycin production. (1980) (11)
- Antitumor effect of a new antibiotic, neothramycin. (1980) (11)
- The chemical synthesis of pepstatin A. (1972) (11)
- An Alternate Synthesis of Leupeptins and Their Analogs (1973) (11)
- Low-molecular-weight immunomodifiers produced by micro-organisms. (1985) (11)
- The crystal and molecular structure of coformycin (1976) (11)
- Formycin-deaminating activity of microorganisms. (1967) (11)
- Synthesis of the 3-O-demethyl and 2"-N-formimidoyl derivatives of istamycin B. (1980) (11)
- Synthesis and antibacterial activity of 6'-N-alkyl derivatives of 1-N-[(S)-4-amino-2-hydroxybutyryl]-kanamycin. (1975) (11)
- Biosynthesis of valanimycin. (1986) (11)
- METHYLSPINAZARIN AND DIHYDROMETHYLSPINAZARIN, GATEGHOL-O-METHYL TRANSFERASE INHIBITORS PRODUCED BY STREPTOMYCES (1973) (10)
- ON THE NEW SOURCE OF CHLOROMYCETIN, STREPTOMYCES OMIYAENSIS (1949) (10)
- Bleomycin Antibiotics: Metal Complexes and Their Biological Action (1986) (10)
- Pharmacokinetics and disposition of 4′-O-tetrahydropyranyladriamycin in mice by HPLC analysis (2004) (10)
- Effect of oxygen concentration on pulmonary fibrosis caused by peplomycin in mice. (1984) (10)
- 3,4-dihydroxystyrene, a novel microbial inhibitor for phenylalanine hydroxylase and other pteridine-dependent monooxygenases. (1984) (10)
- SYNTHESES OF 3''- AND 4''-O-METHYLENEAMINE (1972) (10)
- Synthesis of demethyl derivatives of istamycin A. (1980) (10)
- An antibiotic, plurallin, consisting of a pluramycin-like prosthetic group and a glycoprotein. (1966) (10)
- Chemistry of bleomycin. XXV. Reductive methylation of bleomycin, a chemical proof for the presence of the free secondary amine in bleomycin. (1980) (10)
- THE STRUCTURES OF ILAMYCIN AND ILAMYCIN B2. (1964) (10)
- Unamycin, an antifungal substance produced by Streptomyces fungicidicus. (1960) (10)
- A novel enantiocontrolled synthesis of (+)-9-deacetyl-9-(hydroxymethyl)-4-demethoxydaunomycinone. (1987) (10)
- Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. (1988) (10)
- Biochemical studies of the hatching process in sea urchin embryos. I. Effects of protease inhibitors (1979) (10)
- Synthesis of 3"-epi-dihydrostreptomycin active against resistant bacteria. (1976) (10)
- ON THE STRUCTURE OF NETROPSIN. (1964) (10)
- [12] Electrophoresis of antibiotics (1975) (10)
- Studies on biosynthesis of kasugamycin. IV. Biosynthesis of the kasugamine moiety from [1-14C]-glucosamine and [1,2 or 6-14C]-glucose. (1968) (10)
- Syntheses of All Four Possible Diastereomers of Etoposide and Its Aminoglycosidic Analogues via Optical Resolution of (±) -Podophyllotoxin by Glycosidation with D- and L-Sugars (1987) (10)
- Total Syntheses of Indicine N-Oxide, Intermedine N-Oxide, and Their Enantiomers Using Carbohydrate as a Chiral Educt (1987) (10)
- Studies on low molecular weight immunomodifiers, bestatin, etc. discovery and actions (1984) (10)
- Further studies on inhibition of protein synthesis by fusidic and helvolinic acids. (1967) (10)
- Letter: Chemistry of bleomycin. XIV. Biogenetic-like synthesis of (2S, 3S, 4R)-4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. (1974) (10)
- Purification and properties of an enzyme reducing leupeptin acid to leupeptin. (1981) (10)
- Identity of latumcidin with abikoviromycin. (1958) (10)
- Studies on inhibition of adenosine deaminase by isocoformycin in vitro and in vivo. (1979) (10)
- Inhibition of the initial dipeptide synthesis of globin chains by the antibiotic enomycin in the reticulocyte lysate. (1976) (10)
- [Experimentally induced bleomycin pulmonary toxicity--comparison of the systemic (intraperitoneal) and local (intratracheal) administration]. (1983) (10)
- Synthesis of 5''-deoxylividomycin B. (1972) (10)
- The effect of fusidic acid on protein synthesis in a mammalian system. (1969) (9)
- The Leeuwenhoek Lecture, 1982 - Studies of microbial products in rising to the challenge of curing cancer (1983) (9)
- Vanoxonin, a new inhibitor of thymidylate synthetase. III. Inhibition of thymidylate synthetase by vanoxonin-vanadium complex. (1985) (9)
- Chemistry of bleomycin. XXVI. Biosynthetic study using 13C-enriched precursors. (1980) (9)
- Recent advances in microbial secondary metabolites: inhibitors of hydrolytic enzymes. (1979) (9)
- ILOLATION AND CHARACTERIZATION OF LABILOMYCIN, A NEW ANTIBIOTIC. (1963) (9)
- Bestatin, a stimulator of polysome assembly in T cell lymphoma (L 5178y). (1981) (9)
- ON THE DIFFERENTIATION OF STREPTOMYCIN AND ALLIED SUBSTANCES (STREPTOTHRICIN GROUP) AND RAPID ISOLATION OF STREPTOMYCIN-PRODUCING STRAIN (1948) (9)
- Studies on antitumor substances produced by microorganisms. IV. Sarkomycin-producing Streptomyces and other two Streptomyces producing the anti-tumor substance No. 289 and caryomycin. (1953) (9)
- Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine. (1974) (9)
- Synthesis of tetra-N-phenylalkylkanamycins and their antimicrobial activities. (1968) (9)
- Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. (1984) (9)
- ISOLATION OF A CRYSTALLINE ANTIBIOTIC SUBSTANCE FROM A STRAIN OF STREPTOMYCES AND ITS IDENTITY WITH CHLOROMYCETIN (1948) (9)
- Mechanism of action of neothramycin. II. Interaction with DNA. (1979) (9)
- Frontiers of Antibiotic Research (1987) (9)
- Mitogenic potentials of bestatin, amastatin, arphamenines A and B, FK-156 and FK-565 on spleen lymphocytes. (1985) (9)
- Activity of bottromycin against Mycoplasma gallisepticum. (1968) (9)
- Studies on Glyoxalase Inhibitor Isolation of a New Active Agent, MS-3, from a Mushroom Culture (1975) (9)
- Deglyco-bleomycin-iron complexes: implications for iron-binding site and role of the sugar portion in bleomycin antibiotics. (1981) (9)
- Studies on the Biosynthesis of Kanamycins:Part I. Incorporation of 14 C-Glucose or 14 C-Glucosamine into Kanamycins and Kanamycin-Related Compounds (1968) (9)
- A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristics. (1967) (9)
- Studies on formycin and formycin B phosphates. (1965) (9)
- Letter: Synthesis of 1-N-((s)-4-amino-2-hydroxybutyryl)lividomycin A. (1973) (9)
- Stimulation of kanamycin phosphotransferase synthesis in Escherichia coli by 3',5'-cyclic AMP. (1972) (9)
- Studies on antibiotics and enzyme inhibitors. (1987) (9)
- Chemistry of bleomycin. XXIII. Natural abundance 15N-NMR spectroscopic evidence for the structure of bleomycin. (1979) (9)
- Antitumor spectrum of a new anthracycline, (2"R)-4'-O-tetrahydropyranyladriamycin, and effect on the cellular immune response in mice. (1985) (9)
- Enhancement of colony formation of mouse bone marrow cells by ubenimex. (1987) (9)
- Regio-specific total synthesis of (±)-2-hydroxyaklavinone (1984) (9)
- Syntheses and properties of kanamycin C derivatives active against resistant bacteria. (1977) (8)
- VANOXONIN, A NEW INHIBITOR OF THYMIDYLATE SYNTHETASE (1983) (8)
- Studies on variotin, a new antifungal antibiotic. I. Preparations and properties of variotin. (1959) (8)
- Biochemical mechanism of action of substance B-44-P. (1968) (8)
- Brief Communication: Effect of Protease Inhibitors on Focus Formation by Murine Sarcoma Virus (1975) (8)
- Chemical studies on a toxic product of Streptomyces thioluteus, aureothin. (1954) (8)
- The structure of a novel inhibitor of dextransucrase (1981) (8)
- Biochemical Mechanism of Kanamycin Resistance in Mycobacterium tuberculosis (1977) (8)
- Recent advances in antitumor antibiotics. (1978) (8)
- Differential sensitivity of RSVts (temperature-sensitive Rous-sarcoma virus)-infected rat kidney cells to nucleoside antibiotics at permissive and non-permissive temperatures. (1985) (8)
- Syntheses of 5''-deoxylividomycin A and its amino derivative. (1972) (8)
- Vanoxonin, a new inhibitor of thymidylate synthetase. II. Structure determination and total synthesis. (1985) (8)
- Studies on the Biosynthesis of Kanamycins (1968) (8)
- Crystal and molecular structure of clazamycin A. (1979) (8)
- A NEW ANTIBIOTIC, GYGLAMIDOMYGIN (1971) (8)
- The absolute structures of THP-adriamycins. (1984) (8)
- Chemical modification of coriolin B. (1977) (8)
- Crystal and Molecular Structures of Monomethyl Esters of PDE-I and PDE-II, New Inhibitors of Cyclic Adenosine-3', 5'-monophosphate Phosphodiesterase (1978) (8)
- Synthesis of istamycin A. (1979) (8)
- ANTITUMOR ACTIVITIES OF FORMYCIN AND LABILOMYCIN. (1964) (8)
- A new antibiotic indisocin and N-methylindisocin. (1987) (8)
- IMMOBILIZATION OF PHOSPHO-TRANSFERASES OBTAINED FROM RESISTANT BACTERIA (1974) (8)
- Microbial conversion of epsilon-pyrromycinone and epsilon-isorhodomycinone to 1-hydroxy-13-dihydrodaunomcyin and N-formyl-1-hydroxy-13-dihydrodaunomycin and their bioactivities. (1980) (8)
- Total synthesis of indisocin and N-methylindisocin. (1987) (8)
- Chemical modification of oxanosine. I. Synthesis and biological properties of 2'-deoxyoxanosine. (1984) (8)
- Radioimmunoassay of bleomycins. (1985) (8)
- Isolation and synthesis of 2″-N-formimidoylistamycins A and B, new istamycin components (1982) (8)
- The nature of thiol-compounds which trap cuprous ion reductively liberated from bleomycin-Cu(II) in cells. (1987) (8)
- Biological studies on mikamycin. II. Laboratory investigations of mikamycin A and mikamycin B. (1959) (8)
- Revistin found by screening for inhibitors of reverse transcriptase of an oncogenic virus. (1975) (8)
- Heterogeneity among whorl-forming Streptomycetes determined by DNA reassociation. (1974) (8)
- Studies on low-molecular-weight immunomodifiers produced by microorganisms: results of ten years' effort. (1984) (8)
- Letter: Chemistry of bleomycin. XI. The structures of the terminal amines. (1973) (8)
- Isolation and identification of the antifungal active substance in walnuts. (1967) (8)
- Effect of forphenicinol on gamma-interferon production in mice sensitized with BCG. (1986) (8)
- Studies on lignan lactone antitumor agents. IV: Synthesis of glycosidic lignan variants related to α-peltatin (1988) (8)
- Syntheses and antitumor activities of 7-O-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyl)-daunomycinone and -adriamycinone. (1986) (8)
- STUDIES ON THE STREPTOTHRICIN-GROUP-SUBSTANCES ON STREPTOTHRICIN A AND STREPTOTHRICIN B (1949) (8)
- New microbial secondary metabolites under preclinical development for cancer treatment. (1978) (8)
- Effects of o-phenanthroline, 2,2'-dipyridyl and neocuproine on the activities of bleomycin to inhibit DNA synthesis and growth of cultured cells. (1986) (8)
- The structures of coriolin B and C. (1970) (8)
- THIAZOLIDONE ANTIBIOTIC AS AN ANTIMETABOLITE TO BIOTIN (1953) (8)
- CHEMISTRY OF BLEOMYCIN. XIV (1974) (8)
- Cyclamidomycin (desdanine), an inhibitor of nucleoside diphosphokinase of Escherichia coli. (1972) (7)
- Correlation between level of defense against active oxygen in Escherichia coli K12 and resistance to bleomycin. (1982) (7)
- [Generation of superoxide anion by the reaction of bleomycin-Cu (II) with cysteine]. (1987) (7)
- Synthetic approaches to new anthracyclines: 4,11-dideoxy-2-hydroxy-β-rhodomycinone and its glycosides (1984) (7)
- Studies on biosynthesis of kasugamycin. VI. Some relationships between the incorporation of 14C-compounds and the production of kasugamycin. (1968) (7)
- 2''-N-formimidoylsporaricin A produced by Saccharopolyspora hirsuta subsp. kobensis. (1987) (7)
- A new antibiotic, alboverticillin. (1958) (7)
- Studies on phleomycin. (1959) (7)
- Serum dopamine beta-hydroxylase activity in developing hypertensive rats. (1974) (7)
- Studies on the intermediate metabolism of chloramphenicol production. II. On the carbohydrate metabolism of Streptomyces venezuelae. (1953) (7)
- Syntheses of 4′-Deoxykanamycin and 4′-Deoxykanamycin B (1977) (7)
- Reticulol, an Inhibitor of Cyclic Nucleotide Phosphodiesterases (1977) (7)
- An oriented phase II trial of THP-adriamycin in breast carcinoma. (1986) (7)
- Revised structure for arglecin. (1972) (7)
- Syntheses of 6',5",6""-triamino-6',5",6""-trideoxylividomycin a and 6',5"-diamino-6',5"-dideoxylividomycin B. (1976) (7)
- Dopamineβ-hydroxylase and tyrosine hydroxylase activities in spontaneously hypertensive rats after NaCl administration (1975) (7)
- Studies on the Biosynthesis of Kanamycins:Part II. Incorporation of the Radioactive Degradation Products of Kanamycin A or Related Metabolities into Kanamycin A (1969) (7)
- A new antitumor antibiotic: demethylstreptonigrin. (1986) (7)
- Pharmacological action of FD-008, a new dopamine-beta-hydroxylase inhibitor. (1975) (7)
- Letter: Biological effects of azomycin (2-nitro-imidazole): inhibition of ribonucleotide reductase. (1974) (7)
- New anthracycline antibiotics: serirubicin and 1-hydroxyserirubicin. (1985) (7)
- CHEMISTRY OF BLEOMYCIN. XIII (1974) (7)
- A novel fatty acid from laspartomycin. (1970) (7)
- NADH-dependent cinerulose reductase in rat liver microsomes. (1978) (7)
- Therapy of experimental immunologically mediated aplastic anemia in mice by various immunosuppressive and antitumor agents. (1988) (7)
- Degradation studies on kanamycin. (1958) (7)
- One-pot preparation of 1-chlorovinylisocyanides from carbonyl compounds. (1987) (7)
- Mode of action of enomycin, an antitumor antibiotic of high molecular weight. II. Preferential binding of enomycin to mammalian ribosomes. (1967) (7)
- Pepthiomycin, a new peptide antibiotic mixture. (1968) (7)
- 24-hour rhythm of human plasma noradrenaline and the effect of fusaric acid, a dopamine-beta-hydroxylase inhibitor. (1980) (7)
- Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by synthetic polynucleotide. (1970) (7)
- Immunological involvement in pulmonary fibrosis induced by peplomycin. (1985) (7)
- Cinemicrographic analysis of death in synchronously growing mouse L cells after exposure to bleomycin. (1973) (7)
- Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis. (1970) (7)
- RETRO-SYNTHETIC MANIPULATION OF BLEOMYCINS (1982) (7)
- Syntheses of 1-N-(2-aminoethoxycarbonyl)kanamycin A and 1-N-(3-aminopropoxycarbonyl)kanamycin A. (1981) (7)
- Inhibition of fumarase by S-2,3-dicarboxyaziridine. (1985) (7)
- SYNTHESES OF 6''-AMINO-6''-DEOXYLIVI-DOMYCIN B AND 6''-DEOXY-6''-METHYLAMINO- AND 6''-DEOXY-6''-(2-HYDROXYETHYLAMINO)- LIVIDOMYCIN B (1973) (7)
- A new toxic antibiotic, actinoleukin, produced by a streptomycete. (1954) (7)
- A new streptomycin group antibiotic produced by Streptomyces sioyaensis. (1985) (7)
- Synthesis of a Masked Derivative of 3′-Deoxydihydrostreptobiosamine, a Precursor for the Synthesis of 3″-Deoxydihydrostreptomycin (1977) (7)
- Pharmacokinetics and disposition of (2''R)-4'-O-tetrahydropyranyladriamycin in dogs. (1986) (7)
- Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives. (1982) (7)
- Synthesis of 1-N-acyl derivatives of 3', 4'-dideoxy-6'-N-methyl-kanamycin B and their antibacterial activities. (1975) (7)
- Total Synthesis of PDE-II (1979) (7)
- FUSARIG ACID DERIVATIVES: THE EFFECT ON DOPAMINE β-HYDROXYLASE (1973) (7)
- [11] Ion-exchange chromatography of aminoglycoside antibiotics (1975) (7)
- CHEMISTRY OF BLEOMYCIN. XXVIII (1981) (7)
- The structure of ryridomycin. (1967) (7)
- Studies on anti-tumor substances produced by microorganisms. I. On the antitumor substance No. 289. (1953) (7)
- Syntheses of 1-Epikanamycin A and Its 1-N-[(S)-4-Amino-2-hydroxybutyryl] Derivative (1983) (6)
- INACTIVATION OF β-LACTAMASE BY SOME SITE-SPECIFIC REAGENTS (1974) (6)
- Effects of a new adenosine deaminase inhibitor, isocoformycin, on toxicity, antitumor activity and tissue distribution of formycin A and 9-beta-D-arabinofuranosyladenine. (1980) (6)
- STRUCTURES OF BOTTROMYCINS A AND B. (1965) (6)
- Biosynthesis of kasugamycin. II. Biosynthesis of the two-carbon-side chain of kasugamycin. (1968) (6)
- Isolation of alpha-aminoacyl arginines in screening of aminopeptidase B inhibitors. (1980) (6)
- Syntheses of 9-substituted josamycin, 13-substituted isojosamycin and their tetrahydro derivatives. (1981) (6)
- New Drugs in Cancer Chemotherapy (1981) (6)
- Structure of a new isoflavone from fungi and Streptomyces inhibiting dopa decarboxylase. (1976) (6)
- Strong binding of ditrisarubicin B to DNA. (1988) (6)
- Involvement of cytotoxic T-lymphocytes in the antitumor activity of spergualin against L1210 cells. (1987) (6)
- On tertiomycin B produced by Streptomyces eurocidicus. (1955) (6)
- A predominant role of amino groups in the antibacterial action of aminoglycosides: synthesis of hexa- and heptadeoxykanamycin derivatives. (1983) (6)
- Sulfhydryl modification and activation of phenylalanine hydroxylase by dinitrophenyl alkyl disulfide. (1987) (6)
- Enzymes of Catecholamine Biosynthesis and Metabolism in Spontaneously Hypertensive Rats and Hypotensive Effects of the Specific Inhibitors from Microbial Origin (1972) (6)
- The screening of beta-lactamase inhibitors: inhibition by fatty acids produced by bacteria. (1981) (6)
- MECHANISM OF ACTION OF O-CARBAMYL-D-SERINE. (1963) (6)
- Transformation of kanamycin a into 3′-deoxykanamycin A (1981) (6)
- 4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. (1987) (6)
- RESISTANCES OF ANTIBIOTIC STRAINS OF STREPTOMYCES TO CHLOROMYCETIN AND A RAPID ISOLATION METHOD OF CHLOROMYCETIN PRODUCING STRAINS (1949) (6)
- A possible role by bithiazoles of bleomycin in causing double-strand scission of DNA. (1981) (6)
- Miscoding activities of biologically inactivated kanamycins. (1967) (6)
- Biosynthetic Studies of Reticulol, an Isocoumarin, by 13C-NMR Spectroscopy (1977) (6)
- Chemical studies on kasugamycin. 3. Structures of kasuganobiosamine and kasugamycinic acid. (1965) (6)
- Binding of 3-O-acetyl-4"-O-isovaleryltylosin to ribosomes from a macrolide-resistant strain of Staphylococcus aureus. (1982) (6)
- Monocyclic beta-lactam antibiotics: synthesis and antibacterial activity of 4-(substituted ethyl)-2-azetidinone-1-sulfonic acid derivatives. (1987) (6)
- Structure of azomycin (2-nitro-imidazole). (1955) (6)
- THE CHEMISTRY OF BLEOMYGIN. X (1973) (6)
- Studies on Glycosylation of erythro-β-Hydroxy-L-histidine. A Key Step of Bleomycin Total Synthesis (1986) (6)
- Promotion of antibody formation by prostaglandin (1974) (6)
- Reduction of anthracycline glycoside by NADPH--cytochrome P-450 reductase. (1979) (6)
- Purification of phenylalanine hydroxylase from human adult and foetal livers with a monoclonal antibody. (1985) (6)
- Some evidence for interaction of D-cycloserine with DNA. (1982) (6)
- 5'-Hydroxy-2"-N-demethyl-dihydrostreptomycin produced by a Streptomyces. (1985) (5)
- CHEMISTRY OF LABILOMYCIN. (1964) (5)
- Transformation of Dihydrostreptomycin into 3″-Deoxydihydrostreptomycin (1981) (5)
- Synthetic studies on an antitumor antibiotic, bleomycin. XIII. Synthesis of 2-formylpyrimidine, a key intermediate for the pyrimidine moiety of bleomycin. (1985) (5)
- Localization of aminoglycoside 3'-phosphotransferase II on a cellular surface of R factor resistant Escherichia coli. (1976) (5)
- Inhibitory effect of negamycin on polysomal ribosomes of Escherichia coli. (1976) (5)
- Synthesis of 5″-Deoxy-5″-fluorolividomycin B (1983) (5)
- Low-molecular weight immunomodulators produced by microorganisms. (1980) (5)
- FURTHER STUDIES ON THE TRYPTOPHAN-PARTS OF ILAMYCINS. (1964) (5)
- Synthesis and properties of the 6'-C-alkyl derivatives of 3',4'-dideoxykanamycin B. (1979) (5)
- The studies on the chemical derivations of formycin and formycin B. (1966) (5)
- Observation on the simultaneous production of actinoleukin and trichomycin group antibiotic by a Streptomyces. (1956) (5)
- A new antibiotic, ractinomycin. (1955) (5)
- Isolation and Structure of New Isocoumarins (1977) (5)
- Chemical modification of anthracycline antibiotics. V. Synthesis of 2-hydroxyaclacinomycin A by chemical glycosidation. (1983) (5)
- Synthesis of 6-deoxydihydrostreptomycin (1982) (5)
- Neutral proteinases produced by Streptomyces cacaoi var. asoensis. (1970) (5)
- Valanimycin acts on DNA in bacterial cells. (1987) (5)
- Anti-leukemic activity of 15-deoxyspergualin against N-butyl-N-nitrosourea-induced autochthonous rat leukemia. (1986) (5)
- Kasugamycin in pseudomonas infections of the urinary tract. (1967) (5)
- TRANSITION-METAL BINDING SITE OF BLEOMYCIN. A SYNTHETIC ANALOG CAPABLE OF BINDING IRON(II) TO YIELD AN OXYGEN-SENSITIVE COMPLEX (1982) (5)
- Letter: Chemistry of bleomycin. 8. The x-ray structure determination of 4-amino-3-hydroxy-2-methyl-n-valeric acid, an amine component of bleomycin. (1974) (5)
- The structure of arglecin, a new metabolite of streptomyces (1971) (5)
- Studies on antibiotic actinomycetes. VII. Azomycin-producing strain resembling to Nocardia mesenterica. (1954) (5)
- Effect of antibiotics on magnesium ion removal from E. coli ribosome suspensions. (1968) (5)
- Plasmid variability in the istamycin producing strains of Streptomyces tenjimariensis. (1984) (5)
- Cell Surface-Bound Leucine Aminopeptidase: Target of the Immunomodulator Bestatin (1986) (5)
- Oxanosine, a novel nucleoside from actinomycetes. (1981) (5)
- Bagougeramines A and B, new nucleoside antibiotics produced by a strain of Bacillus circulans. II. Physico-chemical properties and structure determination. (1986) (5)
- Alphostatin, an inhibitor of alkaline phosphatase of bovine liver produced by Bacillus megaterium. (1989) (5)
- The studies on the degradation products of formycin and formycin B. (1966) (5)
- Deamination of purine antibiotics by adenosine deaminase. (1965) (5)
- A new antibiotic, 3,6-dihydroxyindoxazene. (1983) (5)
- Studies on anti-tumor substances produced by microorganisms. II. On the process of large scale production and chemical characters of the antitumor substance No. 289. (1953) (5)
- Derivatives of bottromycin A2 and their biological activity. (1967) (5)
- Chemistry of bleomycin. XV absolute configuration of beta-amino-beta-(4-amino-6-carboxy-5-methylpyrimidin-2-yl)-propionic acid, an amine component of bleomycin. (1976) (5)
- Synthesis of dopastin, a dopamine β-hydroxylase inhibitor of microbial origin (1973) (5)
- Opening Lecture History and Development of Biochemical Mechanisms of Resistance to Aminoglycoside Antibiotics and their Active Derivatives (1975) (5)
- Syntheses of 23-C-substituted derivatives of mycaminosyl tylonolide. (1986) (5)
- A new antibiotic, spinamycin. (1966) (5)
- Antitumor effect of forphenicinol, a low molecular weight immunomodifier, in combination with surgery on Meth A fibrosarcoma, Lewis lung carcinoma, and adenocarcinoma 755. (1986) (5)
- Chemical modification of the ester group of diketocoriolin B. (1980) (5)
- Isolation of actinomycin A from a strain of Streptomyces. (1948) (5)
- Synthesis of 5-O-(4-deoxy-4-fluoro-β-D-mycaminosyl)tylonolide (1987) (5)
- A new source of fradicinmycelin like antifungal antibiotic. (1959) (5)
- Synthesis of 3-deazaoxanosines, C-nucleoside isosteres of oxanosine (1985) (5)
- On Streptomyces cinnamonensis n. sp., the source of an antitubercular antibiotic of low toxicity. (1953) (5)
- Reduction of cinerulose in aclacinomycin-A by soluble and microsomal cinerulose reductases. (1979) (5)
- Met5-enkephalin-Arg6-Phe7 inhibition of noradrenaline and acetylcholine release from peripheral organs. (1984) (5)
- The role of bestatin, an inhibitor of cell surface proteases, in the interaction of serum with untransformed cells in culture. (1981) (5)
- Studies on Streptomyces kanamyceticus, producer of kanamycin. (1959) (5)
- New Anthracycline Antibiotic CG12 Obtained by Microbial Glycosidation of α-Citromycinone (1986) (5)
- NEW INHIBITORS OF MICROBIAL ORIGIN FOR DOPAMINE-β-HYDROXYLASE (1973) (5)
- Studies on the mechanism of the agglutination; on the lattice theory. (1948) (4)
- Role of intramuscular enzymatic changes in the development of muscular weakness in rats with experimental allergic neuritis (1984) (4)
- Studies on the production of griseolutein. (1953) (4)
- Interaction of bleomycin with nucleic acids as probed by ESR spectrometry of iron(II)-nitrosyl complex of bleomycin. (1981) (4)
- Characterization and active fragment of phenomycin, an antitumor polypeptide antibiotic. (1969) (4)
- A crystalline antibacterial substance from Penicillium leucopus and four other strains of Penicillia, and Aspergillus clavatus, and its probable identity with patulin. (1948) (4)
- Inhibition of RNA polymerase of Escherichia coli by an antimicrobial substance B44P (streptovaricin). (1968) (4)
- KF77-AG6, an antipain-related metabolite. (1974) (4)
- Acrylamidine, an anti-fungal substance produced by a Streptomyces. (1968) (4)
- Studies on the effects of actinomycin, cycloheximide, and other known antibiotics on Ehrlich carcinoma of mice. (1955) (4)
- [Changes of anticancer activity and pulmonary toxicity of bleomycins in differences of administration schedules and routes in mice]. (1984) (4)
- FOUR MINOR ANTIBIOTICS FROM MACARBOMYCINS (1973) (4)
- Antibiotic-sensitivity of ribosomes from kanamycin-resistant E. coli. (1967) (4)
- TAXONOMICAL STUDIES OF THE STREPTOMYCES PRODUCING ANTIMYCIN A-BLASTMYCIN GROUP ANTIBIOTICS (1959) (4)
- Chemical derivation of antibiotics active against resistant bacteria. (1968) (4)
- N-Substituted derivatives of 23-amino-4',23-dideoxymycaminosyl tylonolide. Synthesis and antibacterial activity. (1985) (4)
- Fluorospectrometric studies on neothramycin and its reaction with DNA. (1981) (4)
- TAXONOMICAL STUDIES ON A STREPTOMYCES STRAIN PRODUCING LABILOMYCIN. (1963) (4)
- Chemistry of bleomycin. 3. The sugar moieties of bleomycin A2. (1969) (4)
- Inhibition of DNA replication and membrane transport of some nutrients by clazamycin in Escherichia coli. (1984) (4)
- Chemical studies on kasugamycin. II. The structure of methylkasugaminide. (1965) (4)
- Neopluramycin, an inhibitor of nucleic acid synthesis. (1971) (4)
- Synthesis of 1-N-(2-aminoethanesulfonyl)-kanamycins and related aminoglycoside antibiotics. (1983) (4)
- Antitumor effect of pluramycin crude powder on Ehrlich carcinoma of mice. Studies on antitumor substances produced by microorganisms. X. (1956) (4)
- 1-(2-(3, 4, 5, 6-Tetrahydropyridyl))-1, 3-pentadiene an N-methyltransferase inhibitor produced by actinomycetes. (1974) (4)
- The chemical conversion of gentamine C1a into gentamine C2 and its 6'-epimer. (1979) (4)
- Studies on chronic toxicity of kanamycin. (1958) (4)
- Syntheses of Bestatin and Its Analogues and their Bioactivity (1980) (4)
- A new antitumor antibiotic, dioxolamycin. (1984) (4)
- Synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]-3'-deoxyribostamycin (3'-deoxybutirosin B). (1976) (4)
- THE STRUCTURE OF GRISEOLUTEIN B. (1964) (4)
- Pluramycin complex with human serum albumin and the antitumor activity. (1966) (4)
- CHEMISTRY OF BLEOMYCIN. XII: IS0 -BLEOMYCIN A 2 , A PRODUCT OF CARBAMOYL GROUP MIGRATION (1973) (4)
- Microbial secondary metabolites with potential use in cancer treatment. (Plasmid involvement in biosynthesis and compounds. (1977) (4)
- Synthesis of 6′-Amino-1- N -[( S )-4-Amino-2-Hydroxybutyryl]-6′-Deoxylividomycin A (1975) (4)
- Biological studies on mikamycin. IV. Blood and tissue levels of tritiated mikamycins A and B. (1962) (4)
- Biological studies on kanamycin-di-N- and tetra-N- methanesulfonates and fradiomycin (neomycin)-N-methanesulfonate. (1959) (4)
- The screening of antitoxoplasmic substance produced by streptomycete and anti-toxoplasmic substance No. 534. (1955) (4)
- An antibiotic, phthiomycin. (1953) (4)
- A novel deoxyribonuclease inhibitor from Micromonospora. (1982) (4)
- Structure and Synthesis of Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (4)
- Biochemical method of screening of microbial products exhibiting antitumor activity. (1966) (4)
- Chemical studies on kasugamycin. IV. Synthetic transformations of kasuganobiosamine to kasugamycinic acid, isokasugamycinic acid, and their amides. (1965) (4)
- Isolation, racemization and absolute configuration of siderochelin A. (1982) (4)
- TOTAL SYNTHESIS OF BLEOMYCIN A2 (1982) (4)
- The Reaction Mechanism of Rat Liver Glyoxalase I and Its Inhibition by MS-3 (1976) (4)
- Screening studies of antiviral substances produced by actinomycetes and new antiviral substances, niromycins. (1960) (4)
- Effect of pluramycin A on Ehrlich carcinoma of mice; studies on antitumor substance produced by actinomycetes. XIII. (1957) (4)
- Studies on streptothricin BI produced by S. fradiae. (1950) (4)
- Characterization of the dehydrodicaffeic acid dilactone-forming enzyme and the enzymic and chemical synthesis of this mushroom product. (1977) (4)
- Biological properties of macarbomycin, an antibiotic containing phosphorus. (1973) (4)
- Suppression of humoral immunity in mice by spergualin. (1987) (4)
- Negative control for the expression of streptomycin resistance gene from streptomycin-producing Streptomyces griseus. (1986) (4)
- Chemical studies on kasugamycin. I. Acid degradation. (1965) (4)
- Radioimmunoassay for aclacinomycin A. (1982) (4)
- Biological studies on bottromycin A and its hydrazide. (1966) (4)
- Screening of microbial inhibitors of mammalian ornithine decarboxylase. (1985) (4)
- Effect of forphenicinol on the production of Ia-positive macrophages in mice with or without L1210 leukemia and on the growth of L1210 in immunized mice. (1986) (4)
- Serum Dopamine β-Hydroxylase Activity in Developing Spontaneously Hypertensive Rats and the Effect of Salt Administration (1975) (3)
- Synergistic effect of peplomycin in combination with bleomycin on L5178y mouse lymphoma cells in vivo. (1984) (3)
- STUDIES ON AN ANTIBIOTIC SUBSTANCE OF S. GRISEUS, GRISEIN (1949) (3)
- Inhibition of DNA synthesis by griseolutein in Escherichia coli through a possible interaction at the cell surface. (1978) (3)
- STRUCTURE OF LABILOSE, A METHANOLYSIS PRODUCT OF LABILOMYCIN. (1964) (3)
- The structure of coriolin, a new sesquiterpene antibiotic (1969) (3)
- The Crystal and Molecular Structure of a Dibromo-derivative of MS-3: a Glyoxalase I Inhibitor Produced by a Mushroom, Stereum hirsutum (1976) (3)
- Biological studies on mikamycin. (1958) (3)
- Studies on actinoleukin; relation to echinomycin and levomycin. (1958) (3)
- The total syntheses of (−)-indicine N-oxide and intermedine N-oxide (1986) (3)
- Studies on a new antibiotic, exfoliatin, produced by a strain of Streptomyces. (1952) (3)
- Studies on the mechanism of the agglutination; on the quantitative relation between the surface area of the bacteria and the binding agglutinin. (1948) (3)
- Studies on antimicrobial substance B 44 P (streptovaricin) produced by a strain of actinomycetes. IV. Biochemical mechanism of action of substance B 44 P. (1968) (3)
- Studies on the intermediate metabolism of chloramphenicol production. I. Changes of amino acids during fermentation and utilization of amino acids for chloramphenicol production. (1950) (3)
- AMETABOLITE OF BLEOMYCIN A5 IN RABBIT URINE (1974) (3)
- BIOGENESIS OF VARIOTIN:III. INCORPORATION OF 14 C-GLUTAMIC ACID INTO VARIOTIN (1962) (3)
- Nitrosporin, antibiotic from Streptomyces nitrosporeus active to Gram positive bacteria. (1951) (3)
- Reversal of resistance by N-acetyltyramine or N-acetyl-2-phenylethylamine in doxorubicin-resistant leukemia P388 cells. (1987) (3)
- The existence of griseolutein A and B. (1954) (3)
- Biochemical and Biological Studies on Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (3)
- Studies on mikamycin. II. Comparative studies on mikamycin with streptogramin and the antibiotic No. 899. (1958) (3)
- Syntheses of 23-C-alkylidene, and 23-N-containing derivatives of 5-O-mycaminosyltylonolide. (1987) (3)
- Inhibition of R-factor transfer and phage infection by requinomycin. (1972) (3)
- Inhibition of dopamine-beta-hydroxylase, A copper enzyme, by bleomycin. (1980) (3)
- SELECTIVE TOXICITY OF KANAMYCIN AND STREPTOMYCIN. (1964) (3)
- Protective effect of forphenicinol, a low molecular weight immunomodifier, against infection with Pseudomonas aeruginosa in mice and its mechanisms. (1987) (3)
- Biosynthesis of Neothramycin (1978) (3)
- Synthetic Studies on an Antitumor Antibiotic Bleomycin. A Synthetic Analogue Equivalent to Bleomycin in Activating Molecular Oxygen (1986) (3)
- Production and extraction of niromycins, antiviral antibiotics. (1960) (3)
- On screening of antiviral substances produced by streptomyces and on an antiviral substance achromoviromycin. (1953) (3)
- PURIFICATION AND CHARACTERIZATION OF A SIALIDASE INHIBITOR (2006) (3)
- Potentiation of the bleomycin, arabinofuranosylcytosine and adriamycin-caused inhibition of DNA synthesis in lymphocytes by bestatin in vitro. (1985) (3)
- Purification and Properties of a Dehyrodicaffeic Acid Dilactone-forming Enzyme from a Mushroom, Inonotus sp. K-1410 (1977) (3)
- Effect of forphenicinol on the production of lipopolysaccharide-induced interferon and tumor necrosis factor and on the growth of Meth A fibrosarcoma in mice. (1987) (3)
- Adrenal enzymes of catecholamine biosynthesis and metabolism in spontaneously hypertensive rats (1971) (3)
- ISOLATION OF STREPTOMYCIN FROM A PINK VARIANT OF S. GRISEUS (1948) (3)
- Tetra-O-methyldehydrodicaffeic acid dilactones, (+) and (−) isomers (1977) (3)
- A new antibiotic, 2-hydroxy-5-iminoazacyclopent-3-ene. (1979) (3)
- An inhibitor of (Na+, K+)-ATPase produced by Streptomyces pseudovenezuelae MF722-02; purification and properties. (1982) (3)
- New Plasmid‐Mediated Phosphorylation of Gentamicin C in Staphylococcus aureus (1978) (3)
- Effect of sarkomycin on experimental animal tumors. (1955) (3)
- BIOGENESIS OF VARIOTIN (1962) (3)
- Studies on mikamycin. I. (1958) (3)
- Lower toxic derivatives of antibiotics. I. N-methanesulfonate derivatives of kanamycin and neomycin. (1959) (3)
- Inhibition of tyrosine hydroxylase, a Fe(II)-stimulated monooxygenase, by bleomycin. (1980) (3)
- Dynamic Relationship between Hydrolytic Enzymes and the Immune System in Rheumatic Diseases (1987) (3)
- Some chemical modifications of istamycin B. (1983) (3)
- A NEW AMINO ACID FROM ILAMYCIN B1 AND THE STRUCTURE OF ILAMYCIN B1. (1964) (3)
- Fundamental studies on bestatin: a small molecular microbial product enhancing immune response. (1981) (3)
- A new antifungal substance of streptomycetes, seligocidin. (1954) (3)
- Chemistry of variotin. (1960) (3)
- THE STRUCTURAL DIFFERENCE AMONG ILAMYCIN, ILAMYCIN CL AND ILAMYCIN C2. (1965) (3)
- Specific increase in thymidine transport at a permissive temperature in the rat kidney cells infected with srcts-Rous sarcoma virus. (1984) (3)
- The Improvement of Productivity and Selective Production of Arphamenines by Addition of Their Biosynthetic Precursors (1984) (3)
- Immunological cross-reactivities of various anthracycline antibiotics against aclacinomycin A antisera. (1982) (2)
- Low molecular weight immunomodifiers produced by microorganisms. (1985) (2)
- Biosynthesis of oncostatic antibiotics: artificial bleomycins. (1972) (2)
- Inhibition of Cyclic Nucleotide Phosphodiesterases by Reticulol (1977) (2)
- Phenomycin, toxicity and distribution. (1971) (2)
- Proceedings : an international conference on trends in antibiotic research : genetics, biosyntheses, actions & new substances (1982) (2)
- Activation of bleomycin-Fe(III) by bleomycin-Cu(II) and cysteine. (1987) (2)
- On an antibiotic, sarcidin, produced by Streptomyces n. sp. S. achromogenes. (1953) (2)
- Letter: Two beta-lactamase inhibitors produced by a streptomyces. (1973) (2)
- Paper chromatographic studies on methanesulfonates of kanamycin and fradiomycin (neomycin). (1959) (2)
- A new antibiotic, gougeroxymycin. (1969) (2)
- Inhibition of melanoma tyrosinase by fusaric acid (1972) (2)
- Studies on the potency test of tuberculin. (1948) (2)
- Effects of biopolymers and magnesium on the mikamycins inhibition of polyphenylalanine synthesis and the synergistic action of mikamycins A and B. (1967) (2)
- Biosynthesis of leupeptin. IV. Is protein turnover in leupeptin producer cells affected by leupeptin? (1980) (2)
- ISHIZUKA STUDIES ON THE MECHANISM OF ANTITUMOR EFFECT OF BLEOMYICIN ON SQUAMOUS CELL CARCINOMA (1972) (2)
- Effect of forphenicinol, a low molecular weight immunomodifier, on the growth of and the immune responses to murine lymphoma EL4. (1987) (2)
- Antitumor antibiotics and low molecular weight immunomodifiers of microbial origin. (1984) (2)
- Biochemical study of R-75-1, a new semi-synthetic rifamycin. (1981) (2)
- The differentiation-promoting potential of a cytostatic fluoro-pyranosyl adriamycin analog (FAD 104). (1989) (2)
- Bestatin Suppresses the Serum Levels of Several Hydrolytic Enzymes in a Patient with Progressive Muscular Dystrophy (1986) (2)
- The 6'-amidine derivatives of amikacin and dibekacin. (1984) (2)
- Chemical modification of 3'-deoxyamikacin. (1982) (2)
- Alkaline hydrolysis of mikamycin A. (1959) (2)
- Anti-inflammatory neutral proteinases, retikinonase I and II obtained from Streptomyces verticillatus var. zynogenes. (1970) (2)
- Synthesis of 4'-O-acylanthracyclines (1988) (2)
- Studies on the surface culture for the penicillin production. (1948) (2)
- Identification of an antibiotic produced by S. galbus, n. sp. with streptomycin. (1959) (2)
- Inhibition of human serum dopamineβ-hydroxylase after the oral administration of fusaric acid (1972) (2)
- A method of screening for antibiotics producing oxygen radicals. (1982) (2)
- Chapter 12 Enzyme Inhibitors Produced by Microorganisms (1989) (2)
- Mode of action of enomycin, an antitumor antibiotic of high molecular weight. (1966) (2)
- On screening method of antiviral substances produced by Streptomyces and on an antiviral substance, achromoviromycin. (1953) (2)
- Antibiotics and Their Uses (1965) (2)
- Mechanisms of R-Mediated Streptomycin Resistance in Pseudomonas Aeruginosa (1977) (2)
- Correlation between serum dopamine-β-hydroxylase activity and dopamine-β-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands (1977) (2)
- Recent Chemical Studies of Bioactive Microbial Products: Genetics, Active Structures, Development of Effective Agents with Potential Usefulness (1979) (2)
- An neutral proteinase obtained from Streptomyces griseolus. (1970) (2)
- Anti-biotin activity of thiazolidone antibiotic. (1953) (2)
- MECHANISM OF ACTION OF ANGUSTMYCINS, MIKAMYCINS, AND PHLEOMYCIN. (1963) (2)
- BIOSYNTHESIS OF DAUNOMYCINONE FROM AKLAVINONE AND e-RHODOMYCINONE (2006) (2)
- Induction of DNA polymerase alpha and terminal deoxynucleotidyl transferase in the human lymphoblastoid cell line Molt-4 by the immunomodulator bestatin. (1984) (2)
- Antitumour activity of new semi-synthetic anthracyclines containing fluorotalopyranose. (1988) (2)
- Inhibition of brain prostaglandin D synthetase and prostaglandin D2 dehydrogenase by some saturated and unsaturated fatty acids. (1983) (2)
- Determination of impurities in aluminum metals by proton activation (1979) (2)
- Recent Studies on Antibiotics and Low Molecular Weight Enzyme Inhibitors (1982) (2)
- GUEST EDITORIAL – PROBLEMS AND TRENDS IN THE DEVELOPMENT OF NEW ANTIBIOTICS AND OTHER USEFUL MICROBIAL PRODUCTS (1981) (2)
- BIOGENESIS OF VARIOTIN:II. INCORPORATION OF 14 CH 3 SCH 2 CH 2 CH(NH 2 )CO 2 H INTO VARIOTIN (1962) (2)
- An antibacterial substance from several strains of penicillia and its probable identity with penicillin. (1948) (2)
- STUDIES ON THE MECHANISM OF THE AGGLUTINATION IV. THE AGGLUTININ ATTACHING TO THE BACTERIA IN THE PROZONE AND THE SIZE OF THE AGGLUTININ (1948) (2)
- Thirty-five Years with Bioactive Microbial Products (1979) (2)
- RAROMYCIN, A NEW TUMOR-INHIBITORY ANTIBIOTIC PRODUCED BY A STREPTOMYCES (1958) (2)
- Synthesis of 3''-deoxydihydrostreptomycin active against resistant bacteria. (1976) (2)
- On antitumor effect of sarkomycin-INH. (1958) (1)
- [Future of chemotherapy]. (1969) (1)
- STUDIES ON BIOSYNTHESIS OF 3-AM1NO-3-DEOXY-D -GLUCOSE (2006) (1)
- The influence of the phenylacetic acid, paranitrophenylacetic acid, paraaminophenylacetic acid and paraoxyphenylacetic acid on the penicillin production by surface culture. (1948) (1)
- Biogenesis of C13-hydroxy acid moiety of variotin. (1962) (1)
- Letter: New components of bleomycin. (1973) (1)
- Studies on the influence of penicillin and patulin on the respiration of bacteria. (1948) (1)
- Prumycin produced by Bacillus cereus. (1983) (1)
- Structural studies on griseolutein B, phenazine antibiotic. (1957) (1)
- Studies on structure and activity of kanamycins and kanamycin-related compounds. (1968) (1)
- Antibiotics produced by Nocardia mesenterica and a new antibiotic, mesenterin. (1955) (1)
- Studies on antitumor antibiotics. (1959) (1)
- Letter: Hydroxypepstatin, a new peptatin produced by Streptomyces. (1973) (1)
- A new method of testing the potency of tuberculin. (1948) (1)
- SYNTHESIS OF 5“-DEOXY-5”-FLUOROLIVIDOMYCIN B (1983) (1)
- Studies on mikamycins. (1963) (1)
- STEREOSPECIFIC TRANSFORMATION OF D-SUGAR TO L-SUGAR IN COMPLEX AMINOGLYCOSIDE. SYNTHESIS OF KANAMYCIN B ANALOG HAVIN 2,6-DIAMINO-2,4,6-TRIDEOXY-L-ARABINO-HEXOPYRANOSE (1981) (1)
- Syntheses of 6', 5'', 6''''-triamino-6', 5'', 6''''-trideoxylividomycin A and 6', 5''-dideoxylividomycin B. (1976) (1)
- Development of resistance and cross resistance relation between kanamycin and streptomycin. (1959) (1)
- Bottromycin action on macromolecular biosynthesis. (1967) (1)
- Structure-Activity Study on the Kasugamycin Family (1976) (1)
- ON THE MOLECULAR FORMULA AND BACTERIOSTATIC ACTION OF CHLOROMYCETIN (1949) (1)
- Studies on antitumor substances of microbial origin. (1961) (1)
- Amidinomycin from Streptomyces kasugaensis producing kasugamycin. (1968) (1)
- Letter: Preparation of bleomycinic acid: hydrolysis of bleomycin B2 by a Fusarium acylagmatine amidohydrolase. (1973) (1)
- [Uptake and translocation of 14C-labelled Kasugamycin in rice plants]. (1967) (1)
- SYNTHETIC STUDIES ON AN ANTITUMOR ANTIBIOTIC, BLEOMYCIN. XIII. SYNTHESIS OF 2-FORMYLPYRIMIDINE, A KEY INTERMEDIATE FOR THE PYRIMIDINE MOIETY OF BLEOMYCIN (1985) (1)
- ISOLATION AND PROPERTIES OF VALANIMYCIN, A NEW (2006) (1)
- A product of Streptomyces exhibiting strong inhibition against Ehrlich carcinoma cells in vitro. (1959) (1)
- Degradation studies on danomycin. (1966) (1)
- TRANSFORMATION OF DIHYDROSTREPTOMYCIN INTO 3“-DEOXYDIHYDROSTREPTOMYCIN (1981) (1)
- [Secondary microbial metabolites with potentials for antineoplastic actions: antineoplastic antibiotics and immunopotentiators]. (1983) (1)
- Bestatin: A Low Molecular Immunomodifier (1986) (1)
- [Anti-tumour effects of sarkomycin]. (1954) (1)
- Kanamycin and other water-soluble basic antibiotics. (1960) (1)
- [Progress in basic studies of kanamycin. I. Structure and biosynthesis]. (1967) (1)
- In a new antibiotic,exfoliatin,produced by a strain of streptomyces (1952) (1)
- Syntheses of 2′,3′-Dideoxykanamycin A, 2′,3′-Dideoxyamikacin and Related Substances (1987) (1)
- Effect of oudenone on adrenal tyrosine hydroxylase activity in vivo and on tissue catecholamine concentrations. (1971) (1)
- Preferential effects of antibiotics on E. coli strains carrying plasmids. (1974) (1)
- TOTAL SYNTHESIS OF DEGLYCOBLEOMYCIN A2 (1981) (1)
- Man-designed bleomycins. Iron complexation and nucleotide sequence cleavage by synthetic models of bleomycin (1988) (1)
- Studies on New Microbial Secondary Metabolites with Potential Usefulness: Antibiotics, Enzyme Inhibitors, and Immunomodifiers (1984) (1)
- [Antitumor effect of bestatin combined with bleomycin against hepatoma AH 66 subcutaneously transplanted in rats]. (1984) (1)
- [Origin and bases of cancer chemotherapy (author's transl)]. (1978) (1)
- Production and Isolation of Dopastin, an Inhibitor of Dopamine β-Hydroxylase (1974) (1)
- Synthesis of (14R)‐ and (14S)‐14‐De(hydroxymethyl)‐14‐hydroxymycaminosyl Tylonolides. (1987) (1)
- Total Syntheses of Indicine N‐Oxide, Intermedine N‐Oxide, and Their Enantiomers Using Carbohydrate as a Chiral Educt. (1988) (1)
- Bacteriological and pharmacological studies on methanesulfonates of kanamycin and fradiomycin (neomycin). (1959) (1)
- STUDIES ON THE MECHANISM OF THE AGGLUTINATION (1948) (1)
- Synthesis and antitumor activity of 4'-O-acylanthracyclines. (1992) (1)
- Studies on metabolism of a chloramphenicol-producing Streptomyces with chlorine-36. (1959) (1)
- Studies on bleomycin. (1967) (1)
- Relative deficiency of serine proteinase activities in spleen of aged mice (1987) (1)
- Production of 3-carboxy-2,4-pentadienal lactol by a streptomyces and its antitumor activity. (1962) (1)
- INHIBITION OF RESISTANT DYSENTERY BACILLI BY PHLEOMYCIN. (1963) (1)
- [Some antineoplastic substances produced by microorganisms]. (1962) (1)
- Bestatin, a low molecular weight immunomodifier produced by microorganisms (1987) (1)
- Specific inhibition of aspartase by S-2,3-dicarboxyaziridine. (1988) (1)
- Studies on the effects of griseolutein B. (1953) (1)
- Raromycin, a new tumorinhibitory antibiotic produced by a Streptomyces. I. Studies with Ehrlich carcinoma and Croker sarcoma 180 of mice. (1957) (1)
- STUDIES ON THE MUTATION OF STREPTOMYCES GRISEUS NO. 200 BY X-RAY IRRADIATION (1950) (1)
- Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products (1973) (1)
- Recent Studies on Antitumor Antibiotics (1979) (1)
- Inactivation of aminoglycosidic antibiotics by resistatt organisms. (1968) (1)
- Biological studies on mikamycin. III. Influence of blood on the activity and further investigations on the activity against experimental infections. (1962) (1)
- [Effects of mitomycin and some other substances produced by streptomyces upon Yoshida sarcoma]. (1953) (1)
- Serum dopamine-β-hydroxylase in spontaneously hypertensive rats (1972) (1)
- ISOLATION OF PENICILLIN G N-ETHYLPIPERIDINE SALT AND SODIUM SALT AND THEIR STABILITY (1948) (0)
- Leupeptine and their analogues (1969) (0)
- Inhibition of the bacteriostatic effect of kanamycin by brain. (1959) (0)
- Process for the preparation of adriamycin-4'-O-derivatives or acid addition salts thereof (1981) (0)
- Inhibition of dopamine beta-hydroxylase by aquayamycin. (1968) (0)
- A compound with anti-tumor effect and antimicrobial effect, its microbiological production, and its use as a medicament (1986) (0)
- Peptides, process for their preparation and their therapeutic use (1978) (0)
- SUGAR MOIETY OF BLEOMYCINS (1972) (0)
- [Prospects in the development of antibiotic agents]. (1981) (0)
- Immobilized phenylalanine hydroxylase through the SH groups. (1986) (0)
- A process for the preparation of O-acyl josamyciner. (1969) (0)
- Derivatives of antibiotics of the pluramycin group, their preparation and use (1985) (0)
- Studies on the mechanism of the agglutination; heterogeneity of the agglutinin in the antiserum. (1948) (0)
- New analgesic agent (1981) (0)
- Spergualinaehnliche compounds and manufacturing processes it. (1987) (0)
- Proceedings: Serum dopamine beta-hydroxylase activity in developing spontaneously hypertensive rats and the effect of salt administration. (1975) (0)
- SYNTHETIC STUDIES ON AN ANTITUMOR ANTIBIOTIC, BLEOMYCIN. XIV. THE SYNTHESIS OF BOC-PYRIMIDOBLAMIC ACID (1985) (0)
- Letter: Inactivation of beta-lactamase by some site-specific reagents. (1974) (0)
- Obituary: Dr. Yusuke Sumiki. (1974) (0)
- Method for the preparation of 4 o tetrahydropyranyladriamycin b us patent 4818818 april 4 1989 (1989) (0)
- [On sarkomycin and other actinomycetes products exhibiting antitumor activity]. (1954) (0)
- SYNTHESES OF 1-EPIKANAMYCIN A AND ITS 1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL) DERIVATIVE (1983) (0)
- Correlation between serum dopamine-beta-hydroxylase activity and dopamine-beta-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands. (1977) (0)
- Leucylnegamycin, an antibiotic from negamyhcin-producing Streptomyces. (1971) (0)
- Cellular uptake and efflux and cytostatic activity of 4'-O-tetrahydropyranyladriamycin in adriamycin-sensitive and resistant tumor cell lines.:IN ADRIAMYCIN-SENSITIVE AND RESISTANT TUMOR CELL LINES (1984) (0)
- Bisukaberin, foerfarande Foer the arm in a production foerening and also its anvaendning som laekemedel. (1987) (0)
- BIOGENESIS OF VARIOTIN:I. INCORPORATION OF CH 3 14 CO 2 H AND 14 CH 3 CO 2 H INTO VARIOTIN (1962) (0)
- Studies on Antitumour Antibiotics, Low Molecular Weight Immuno-Modifiers and Their Analogs and Derivatives (1983) (0)
- [Trends in antibiotic research in Japan]. (1963) (0)
- A process for the manufacture of tobramycin (1980) (0)
- GENETICS AND BIOCHEMICAL STUDIES OF CHLORAMPHENICOL- NONPRODUCING MUTANTS OF STREPTOM YCES (2006) (0)
- Process for the preparation of N- (4- (3-aminopropyl) aminobutyl) -2- (omega-guanidino-fatty acid-amido) -2-substituted-ethanamide (1982) (0)
- Mode of resistance and structure-activity;Introduction to the symposium (Symposium on mode of resistance and structure-activity) (1968) (0)
- STUDIES ON AMINOSUGARS PART 35, SYNTHESES OF 3′,4′-DIDEOXYNEAMINE AND 3′- AND 4′-O-METHYLNEAMINES (1974) (0)
- Crystalline gamma-bestatin and process for its preparation (1982) (0)
- Letter: Synthesis of 3',4'-dideoxybutirosin B. (1973) (0)
- OF ANTIBIOTICS BIOSYNTHESIS OF LEUPEPTIN . III ISOLATION AND PROPERTIES OF AN ENZYME (2006) (0)
- New process of producing tobramycin or 3'-deoxy-kanamycin ba from a protected derivative of kanamycin b, and intermediate products obtained during such process (1980) (0)
- PB130 SIASTATIN B, A POTENT SIALIDASE INHIBITOR : THE TOTAL SYNTHESIS, ABSOLUTE CONFIGURATION AND BIOLOGICAL ACTIVITY (1988) (0)
- SYNTHESIS OF 2-AMINO-3-(2-OXO-4-PHENYL-1-AZETIDINYL)PROPIONAMIDE (1981) (0)
- Process for the preparation of 3 ', 4'-dideoxykanamycin B and protected kanamycin B derivatives for use as starting material in the process (1976) (0)
- SYNTHESIS OF COFORMYCIN, STRUCTURE OF COFORMYCIN, AN UNUSUAL NUCLEOSIDE OF MICROBIAL ORIGIN (1974) (0)
- The antibiotic MF 730-N6, its preparation, the microorganism to be used thereby, as well as its use for the preparation of medicinal products (1986) (0)
- A POSSIBLE ROLE BY OF BLEOMYCIN IN DOUBLE-STRAND OF DNA BITHIAZOLES CAUSING SCISSION (2006) (0)
- 6 SYNTHETIC STUDY OF OUDENONE AND RELATED HOMOLOGUES, TYROSINE HYDROXYLASE INHIBITORS (1972) (0)
- United States Patent ( 19 ) (2017) (0)
- A process for the preparation of antibiotics aclacinomycin A and / or B, or salts thereof or deoxyribonucleinsyrekomplekser. (1975) (0)
- STEREOSELECTIVE SYNTHESIS OF (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYLPENTANOIC ACID, AN AMINO ACID CONSTITUENT OF BLEOMYCIN, BY ALDOL CONDENSATION (1982) (0)
- Patents and literature (1986) (0)
- Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis. (1970) (0)
- UDC 577. 156.04.062.072: 615.276.076.9 Alkinonase A and AF, New Alkaline Proteinases produced by Streptomyces violaceorectus1) (2010) (0)
- [Method for determination of the bleomycin inactivating enzyme acitivity in tissues]. (1975) (0)
- 2-Amino-5-methyl-5-hexenoic acid, a methionine analog produced by Streptomyces sp. MF374-C4. (1979) (0)
- SYNTHESIS OF 1‐N‐((S)‐4‐AMINO‐2‐HYDROXYBUTYRYL)‐3′‐DEOXYRIBOSTAMYCIN (3′‐DEOXYBUTIROSIN B) (1977) (0)
- Analgesic action of enkephalinase inhibitor, D-phenylalanyl-2S,3R 3-amino-2-hydroxy-4-phenylbutanoic acid (D-Phe-AHPA) (1983) (0)
- A process for the preparation of a optically active monoalkyl ester of ss- (s) -aminoglutarsaeure (1981) (0)
- Separation chemistry of various elements produced by heavy-ion irradiation (1974) (0)
- Benz (a) anthraquinone compounds, microbial processes for their manufacture and their use as pharmaceuticals. (1986) (0)
- Cylinder plate assay and some studies of isonicotinic acid hydrazide with M. tuberculosis 607. (1952) (0)
- Istamycine and method for manufacturing the same (1980) (0)
- NOVEL 1-n (a-hydroxy-o-aminoalcanoyl of 5,3 ', 4'-trideoxy or 5,3', 4'-trideoxy-6'-n-methyl- or 5,3 ', 4 ', 6' '- tetradesoxykanamycine b, their production processes and antibacterial compositions containing them (1981) (0)
- L-argininalderivate, processes for their preparation and pharmaceutical compositions containing them (1981) (0)
- Novel derivatives of istamycins a and b and process for their preparation and pharmaceutical application (1981) (0)
- Spergualinderivater, process for their preparation, pharmaceutical composition in which they are incorporated, and a method for preparing the composition (1992) (0)
- COLI CARRYING R FACTOR (2006) (0)
- Lignan Lactone Antitumor Agents. Part 4. Synthesis of Glycosidic Lignan Variants Related to α‐Peltatin. (1988) (0)
- Bacteriostatic effect and toxicity of kanamycin-tetra-N-methanesulfonate. (1959) (0)
- Affinity labeling of an Escherichia coli beta-lactamase. (1973) (0)
- A process for preparing anthracycline derivative r2ox2. (1987) (0)
- [Discovery of dibekacin and its chemical aspects]. (1982) (0)
- Process for the preparation of anthracycline derivatives or acid addition salts thereof (1980) (0)
- Anthracycline glycosides, process for their preparation, pharmaceutical agent containing them and use of anthracyclinglycosiderne for the preparation of medicaments (1985) (0)
- Process for preparation of 5"-amino-3',5" -dideoxyribostamycin (1975) (0)
- STRUCTURE AND SYNTHESIS OF DOPASTIN, AN INHIBITOR OF DOPAMINE BETA-HYDROXYLASE (1975) (0)
- Summary of Structures of Microbial Secondary Metabolites Determines by Dr. H. Umezawa (1979) (0)
- Synthesis of 3′‐Deoxy‐3′‐fluorokanamycin A* and 3′,4′‐Dideoxy‐3′‐ fluorokanamycin A. (1992) (0)
- Spergualin derivatives and their use for the preparation of drugs with immunosuppressive activity (1985) (0)
- NEW ANTHRACYCLINE ANTIBIOTICS: SERIRUBICIN AND 1-H YDROXY SER IR UBI CIN t (2006) (0)
- N- (4- (3-aminopropyl) aminobutyl) -2- (w-guanidino fatty acid amido) -2-substituted ethanamide, their salts and processes for their preparation (1982) (0)
- Sorbents for protease and verfaren for cleaning of tissue plasminogen activator with it. (1985) (0)
- Anthracycline derivatives, methods for their manufacture and their use as pharmaceuticals. (1987) (0)
- Chemistry of the transplutonium elements (1974) (0)
- Tylosin derivatives and process for their preparation (1981) (0)
- 2'-modified kanamycin, processes for making them, as well as medium having antibacterial activity which comprise these modified kanamycin (1982) (0)
- STUDIES ON THE EXTRACTION OF PENICILLIN (1948) (0)
- New derived n-methanesulfonic the demethyl-3-O istamycin b, their preparation and therapeutic compositions containing (1983) (0)
- Analogifremgangsmaade for the preparation of (-) - 15-deoxyspergualing and pharmaceutically acceptable syreadditionsssalte thereof as well as intermediate (1983) (0)
- Derived from l-argininal and method of preparing (1981) (0)
- Synthesis of 2′,3′-Dideoxy-2′-fluorokanamycin A (I). (1986) (0)
- An N- (6-substituted pyridine-2-carbonyl) -3-substituted histidine derivative, process for its preparation and its use as an anti-tumor agent (1985) (0)
- SYNTHESIS OF 3′‐DEOXYKANAMYCIN B (TOBRAMYCIN) (1977) (0)
- [Chemical modification of 3' and 4' positions and antitumor activities of anthracyclines]. (1988) (0)
- Using spergualin or one of its pharmaceutically acceptable salts for the manufacture of a transplantation immunity unterdrueckenden and anti-allergic agent. (1985) (0)
- A Synthetic Approach to the Mechanism of DNA-Cleavage by Bleomycic-Fe(II)-O2 Complex (1984) (0)
- Messenger RNA-associated 30S ribosomal subunit: extraction from E. coli and the effect of chloramphenicol on the content. (1968) (0)
- Novel aminoglycosidic antibiotics, methods of production thereof and antibacterial compositions comprising them (1980) (0)
- Anthracycline derivatives, their preparation and use (1987) (0)
- Chemistry of bleomycin. XXVIII. Preparation of deglycobleomycin by mild acid hydrolysis of bleomycin. (1981) (0)
- Process for the preparation of 3,4i-dideoxykanamycin] (1976) (0)
- [RECENT TRENDS IN ANTICARCINOGENIC ANTIBIOTICS]. (1964) (0)
- A process for the preparation of antibiotics of phleomycingruppen. (1973) (0)
- Total Synthesis of PDE-I (2008) (0)
- bmg162-af2 particular antibiotic having antitumor activity and process for its preparation from a strain of the genus bacillus (1981) (0)
- SYNTHESIS OF A LIVIDOMYCIN B ANALOG, 5-O-(3-O-(2-AMINO-2-DEOXY-α-D-GLUCOPYRANOSYL)-β-D-RIBOFURANOSYL)-3′-# DEOXYPAROMAMINE (1977) (0)
- 67 CHEMICAL STUDIES ON MINOSAMINOMYCIN (1975) (0)
- A process for preparing an antibiotic BMG 162-AF2. (1981) (0)
- Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part II - Small molecular weight immunomodulators produced by microorganisms. (1982) (0)
- Analogifremgangsmaade for the preparation of an N-oe4- (3-aminopropyl) aminobutylaa-2- (omega-guanidino-fedtsyreamido) -2-substituted ethanamide or a salt thereof (1982) (0)
- Antifungal substances, phaeofadin and moldin, produced by Streptomyces. (1952) (0)
- Ka~amycin, Mechanism of Resistance to Aminoglycasides and Development of Derivatives Active Against Resistant Strains: (1979) (0)
- Spergualinbeslaegtede compounds or physiologically acceptable salts thereof, their preparation and use (1986) (0)
- Plipastatin, its preparation and use, as well as in the manufacture useful microorganism (1985) (0)
- Spergualin related compounds, Methods for their preparation and their use as medicaments (1983) (0)
- SYNTHESIS OF A MASKED DERIVATIVE OF 3′‐DEOXYDIHYDROSTREPTOBIOSAMINE, A PRECURSOR FOR THE SYNTHESIS OF 3′‐DEOXYDIHYDROSTREPTOMYCIN (1977) (0)
- Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part I - Antitumor antibiotics and their derivatives. (1982) (0)
- A process for the preparation of 3 ', 4'-dideoxy-kenamycin B. (1971) (0)
- (Received for publication November 25, 1977) Activities of derivatives of dehydrodicaffeic acid dilactone (DDCAD) to inhibit catechol- 0-methyltransferase (COMT), cyclic AMP phosphodiesterase (PDE) and DOPA decarboxy- (2006) (0)
- Effects of antitumor substances on yeasts and their respiration deficient mutants. (1958) (0)
- Preparation of branched 2-deoxy-alpha-glycosides (1976) (0)
- The method and the starting material for the preparation of bestatinderivater (1985) (0)
- VOL. XXI NO. II THE JOURNAL OF ANTIBIOTICS 653 ORYZOXYMYCIN, A NEW ANTIBIOTIC (2006) (0)
- The action of raromycin, a new tumor-inhibitory antibiotic, on transplantable mouse tumors. (1957) (0)
- Preparation of 1,2-dihydro-3h-pyrrolo3,2-eindole derivative (1978) (0)
- A process for preparing an antibiotic substance, kasugamycin, as well as acid addition salts thereof. (1964) (0)
- New antibiotic aminoglycoside derivative has istamycin, process for the preparation and pharmaceutical compositions containing (1981) (0)
- TOTALSYNTH. VON KASUGAMYCIN (1972) (0)
- Cross resistance relation between streptomycin and kanamycin in E. coli and Mycobacterium 607. (1959) (0)
- Mutagenicities of bleomycin derivatives on Salmonella typhimurium TA102 (1984) (0)
- A specific protease inhibitor from Streptomyces. (1986) (0)
- STUDIES ON AMINOSUGARS PART 41, SYNTHESIS OF 1‐N‐((S)‐4‐AMINO‐2‐HYDROXYBUTYRYL)‐3′,4′‐DIDEOXYNEAMINE (1975) (0)
- A process for the preparation of 2'-amino-2'-deoxy-kanamycin. (1968) (0)
- Pharmacological action of FD-008, a new dopamine-beta-hydroxylase inhibitor. III. Effects on endogenous biogenic amine levels in rats. (1975) (0)
- Method of determination of chlortetracycline and some studies on use of chlortetracycline for fish preservation. (1957) (0)
- Ion-exchange chromatography of aminoglycoside antibodies. (1975) (0)
- Studies on Lignan Lactone Antitumor Agents. Part 1. Synthesis of Aminoglycosidic Lignan Variants (II) Related to Podophyllotoxin (I). Studies on Lignan Lactone Antitumor Agents. Part 2. Synthesis of N-Alkylamino- and 2,6-Dideoxy-2-ami (1987) (0)
- THIRTY-FIVE YEARS WSTH BIOACTIVE MICROBIAL (0)
- SYNTHESIS OF 1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL)LIVIDOMYCIN A (1975) (0)
- Spergualin-related compounds having a phenylene group, process for their preparation as well as a pharmaceutical composition (1985) (0)
- Process for the preparation of 4'-O-tetrahydropyranyladriamycin b (1986) (0)
- SYNTHESIS OF CLEONINE (AMINO(1‐HYDROXYCYCLOPROPYL)ACETIC ACID), A NOVEL AMINO ACID CONTAINED IN CLEOMYCIN (1981) (0)
- Antibiotics containing the beta—lactam structure, part 1: by A. L. Demain and N. A. Solomon, Springer Verlag, 1983. DM280 (xvi + 358 pages) ISBN 3 540 12107 2 (1984) (0)
- List of New Antibiotics and Their Derivatives Discovered by Dr. Hamao Umezawa (1979) (0)
- [Preparation of negamycin ointments. I. Possible utility of gel bases]. (1986) (0)
- ON MURINE TRANSPLANTABLE TUMORS AND MICROBIAL INFECTIONS (2006) (0)
- A process for preparing bestatin gamma-form crystal (1982) (0)
- [Chemotherapy by antibiotics]. (1970) (0)
- TOTAL SYNTHESIS OF THE DISACCHARIDE OF BLEOMYCIN, 2-O-(α-D-MANNOPYRANOSYL)-L-GULOPYRANOSE (1981) (0)
- SYNTHESES OF BESTATIN AND ITS ANALOGS AND THEIR BIOACTIVITY (1981) (0)
- STUDIES ON AMINOSUGARS PART 36, SYNTHESES OF 3′,4′-DIDEOXY- AND 3′,4′,5′-TRIDEOXY-RIBOSTAMYCIN (1973) (0)
- BIOGENESIS OF VARIOTIN I. INCORPORATION OF CH314C02H AND 14CH 3CO2H INTO VARIOTIN (2006) (0)
- A process for the preparation of blasticidin S and its addition products (1961) (0)
- THEORETICAL STUDIES ON THE END POINT CURVE OF ROD-SHAPED PARTICLES IN ULTRAFILTRATION (1948) (0)
- Derivatives of aminopropylaminobleomycine their therapeutic applications and process for their preparation (1982) (0)
- ON THE NEW SOURCE OF CILOROMYCETIN, (2009) (0)
- [Preparation of negamycin ointments. II. Improvement in stability and antimicrobial activity]. (1986) (0)
- IRON COMPLEXES OF BLEOMYCIN AND DEGLYCO-BLEOMYCIN : SPECTROSCOPIC PROPERTIES AND NUCLEOTIDE SEQUENCE SPECIFICITY IN DNA CLEAVAGES (1983) (0)
- Mouse leukemia C1498 and antitumor substances. (1959) (0)
- process new derivatives of kanamycin A, as well as manufacturing the same (1981) (0)
- Tissues Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Blood Lung Liver Spleen Kidney Concentration in ug (2006) (0)
- L-argininal derivatives and preparation method (1981) (0)
- N- (4- (3-aminopropyl) aminobutyl) -2,2-dihydroxyaethanamid and methods for its synthesis (1982) (0)
- PERSPECTIVES ON RESEARCH OF ANTIBIOTICS AND LOW MOLECULAR WEIGHT ENZYME INHIBITORS (1983) (0)
- Presence of immunosuppressive agents with various activities in Ehrlich ascites fluid. (1975) (0)
- Studies on Glycosylation of erythro-β-Hydroxy-L-histidine. A Key Step of Bleomycin Total Synthesis. (1986) (0)
- Regio-Specific Total Synthesis of (±)-2-Hydroxyaklavinone. Synthetic Approaches to New Anthracyclines: 4,11-Dideoxy-2-hydroxy-β-rhodomycinone and Its Glycosides. (1984) (0)
- Spergualinderivater, process for their preparation and their use as medicaments (1987) (0)
- THE JOURNAL OF ANTIBIOTICS BIOSYNTHESES OF NEW BLEOMYCINS (2006) (0)
- Aclacinomycins A and B and processes for their preparation (1975) (0)
- SALMONELLA ALACHUA , A NEW SEROTYPE 1 WILLA (0)
- Goriolin B was oxidized by chromic anhydride in acetic acid at 20-'30°C for 16~ (2007) (0)
- Synthesis of 3'- and 4'-O-methylneamine. (1972) (0)
- Process for the preparation of an antibiotic, bmg162 AF2, or a pharmaceutically acceptable salt thereof (1981) (0)
- Derivatives of tylosin (1981) (0)
- Anthracyclines new glycosides and their pharmacological application (1977) (0)
- Synthesis of 3-Deazaoxanosines, C-Nucleoside Isosteres of Oxanosine. (1986) (0)
- Synthetic Studies on Pyrrolizidine Alkaloid Antitumor Agents. Enantioselective Synthesis of Retronecine (I) and Its Enantiomer (II) from D-Glucose. (1986) (0)
- United States Patent ( 19 ) Akita (2017) (0)
- Development of microbial secondary metabolites with potential usefulness (1984) (0)
- Streptovaricin- and rifampicin-resistance of RNA polymerase in a resistant clone of Escherichia coli B. (1968) (0)
- Letter: Fusaric acid derivatives: the effect on dopamine beta-hydroxylase. (1973) (0)
- Antibiotic bmg162-AF2, process for its preparation and pharmaceutical preparation containing anti-tumor activity (1981) (0)
- Therapeutically useful compounds as well as processes for their preparation (1969) (0)
- Studies of the Effect of Spermidine in Enhancing Cellular Immunity (1982) (0)
- Bisucaberin, method for its production and its use as a medicinal product (1987) (0)
- A process for preparing anthracyclinglycosidantibiotika designated MA-144 and MA 144 m1-m2 or non-toxic acid addition salts or complexes with deoxyribonucleic acid (1977) (0)
- INHIBITION OF TYROS 1 NE HYDROXYLASE BY AQUAYAMYCIN (2006) (0)
- Novel threo-3-amino-2-hydroxybutanoylaminoacetic acid (1979) (0)
- Mode of action of enomycin, an antitumor antibiotic of high molecular weight. 3. On the weak inhibition of polyphenylalanine synthesis directed by polyuridylic acid. (1968) (0)
- STUDIES ON AMINOSUGARS PART 40, SYNTHESIS OF BUTIROSIN B AND ITS 3′,4′-DIDEOXY DERIVATIVE (1975) (0)
- SYNTHESIS OF 6′-AMINO-1-N-((S)-4-AMINO-2-HYDROXYBUTYRYL)-6′-DEOXYLIVIDOMYCIN A (1975) (0)
- Foerfarande Foer framstaellning of tumoerfoerhindrande baumycinkomplexet and also its Komponenter (1977) (0)
- Bisucaberin, procedure for its preparation and its use as a medicinal product (1987) (0)
- New process for the preparation of 1-n-isoseryl- or 1-n- (l-4-amino-2-hydroxybutyryl) -3 ', 4'-didesoxykanamycin b and its intermediates zeue (1979) (0)
- Streptomyces galbus nov. sp. and some remarks on Streptomyces producing streptomycin-group antibiotics. (1959) (0)
- Test methods for antitumor substances. (1961) (0)
- The Total Synthesis of (-)-Indicine N-Oxide (I) and Intermediate N-Oxide. (1987) (0)
- Isocoformycin and a method for preparation thereof (1978) (0)
- A kinetic aspect of the antibody production against Ehrlich tumor cells in mice bearing Ehrlich solid tumor. (1975) (0)
- The new, physiologically active substance ebelactone and method for manufacturing the same (1981) (0)
- Enzymatic Changes in Pancreas and Liver of the KK Mouse As an Animal Model of Diabetes Mellitus (1986) (0)
- Screening of Enzyme Inhibitors with Potential Antitumor Activity (1976) (0)
- 1N-(.alpha.-HYDROXY-.omega.-AMINOALKANOYL)-6'N-METHYL-3',4'-DIDEOXYKANAMYCIN B AND THE PRODUCTION THEREOF (1975) (0)
- 2,6-diphenyl-3,7-dioxabicyclo-3.3.0-octane 4,8-dione derivative and anticarcinogens, catechol-o-methyl transferase inhibitors and adenosine 3',5'-cyclic phosphoric acid phosphodiesterase inhibitors containing the derivative as active component (1977) (0)
- [Specific enzyme inhibitors synthesized by micro-organisms]. (1971) (0)
- Siastatin B, a Potent Neuraminidase Inhibitor: The Total Synthesis and Absolute Configuration. (1989) (0)
- [Research progress of secondary metabolites produced by microorganisms--enzyme inhibitors (author's transl)]. (1976) (0)
- Letter: Synthesis of 4-amino-3-hydroxy-6-methylheptanoic acid, an amine component of pepstatin. (1973) (0)
- CATECHOLAMINE SYNTHESIZING ENZYMES IN HYPERTENSION (1976) (0)
- Foerfarande Foer framstaellning of antibiotika aklacinomyciner a and b eller blandningar daerav with antitumor Effect (1975) (0)
- bleomycinique acid substituted on the nitrogen of the amido group (1983) (0)
- Mode of resistance and structure-activity. (1968) (0)
- Papers of Dr. Hamao Umezawa (1979) (0)
- Studies on antifungal substances, phaefacin and moldin, produced by Streptomyces sp. (1952) (0)
- Makrolide Antibiotika-Derivate (1983) (0)
- [Basic information and clinical application of Kanendomycin]. (1969) (0)
- [Progress in basic studies of kanamycin. II. Activity, structure and tolerance mechanism]. (1967) (0)
- Selected Papers of Dr. Hamao Umezawa (1979) (0)
- 1-n - ((s) -alpha-substituted omegaaminoacyl) -neamine or -ribostamycine and methods of making the same (1973) (0)
- Letter: Four minor antibiotics from macarbomycins. (1973) (0)
- Studies on the potency test of penicillin; on the error in the cup assay and Miyamura's rapid method. (1948) (0)
- The Crystal Structure of Formyein Hydrobromide Monohydrate (2001) (0)
- [Biochemical effects of 3',4'-dideoxykanamycin B]. (1973) (0)
- New derivatives of n-methanesulfonic istamycines a and b, their preparation and therapeutic compositions based on these derivatives (1981) (0)
- N- (4- (3-aminopropyl) aminobutyl) -2- (o-guanidino (fatty acid) amido) -ethanamides substituted in position 2 and their salts, process for their preparation and their therapeutic application (1982) (0)
- Kanamycins MODIFIED 2 ', their process of preparation and their use as antibacterial agents (1982) (0)
- Bestatin: a crystal and molecular structure (1981) (0)
- 1127 – ENZYME INHIBITORS OF MICROBIAL ORIGIN (1977) (0)
- Letter: Immobilization of phosphotransferases obtained from resistant bacteria. (1974) (0)
- New process for the preparation of 3'-desoxykanamycin a (1981) (0)
- New physiologically active substance erbstatin analogous compounds (1987) (0)
- Anthracycline derivatives, to processes for their preparation and their use as medicaments. (1987) (0)
- New physiologically active derivatives of esterastins and method for manufacturing the same (1979) (0)
- Process for the preparation of agents antiotiske (1977) (0)
- 3- (4'-aminobutylamino) propylamino-bleomycin derivatives, their preparation and their use as medicaments (1984) (0)
- Anthracycline glycosides, methods for their production and drug (1977) (0)
- REGIO- AND STEREOSPECIFIC SYNTHESIS IN THREO-3-AMINO-2-HYDROXY ACIDS, NOVEL AMINO ACIDS CONTAINED IN AMINOPEPTIDASE INHIBITORS OF MICROBIAL ORIGIN (1980) (0)
- Analogifremgangsmaade for the preparation of compounds spergualinbeslaegtede (1983) (0)
- Discovery of josamycin. (1982) (0)
- 34 SYNTHETIC APPROACH TO BLEOMYCIN (BLM) (1980) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Hamao Umezawa?
Hamao Umezawa is affiliated with the following schools:
