Hidetoshi Yoshimura
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Hidetoshi Yoshimura's Degrees
- PhD Pharmacology University of Tokyo
- Doctorate Medicine University of Tokyo
Why Is Hidetoshi Yoshimura Influential?
(Suggest an Edit or Addition)Hidetoshi Yoshimura's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Analgesic effect of morphine glucuronides. (1971) (378)
- POSSIBLE CORRELATION BETWEEN INDUCTION MODES OF HEPATIC ENZYMES BY PCBs AND THEIR TOXICITY IN RATS (1979) (170)
- Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats. (1973) (145)
- Species difference of site-selective glucuronidation of morphine. (1991) (122)
- Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor. (1998) (108)
- Forensic chemical study on marihuana. I. A detection method of the principal constituents by thin-layer and gas chromatographies. (1968) (97)
- Inhibition of anandamide amidase activity in mouse brain microsomes by cannabinoids. (1996) (96)
- Inductive effect on hepatic enzymes and acute toxicity of individual polychlorinated dibenzofuran congeners in rats. (1981) (89)
- Polychlorinated biphenyls and dibenzofurans in patients with yusho and their toxicological significance: a review. (1984) (82)
- Metabolism in vivo of 3,4,3',4'-tetrachlorobiphenyl and toxicological assessment of the metabolites in rats. (1987) (77)
- Sex difference in the oxidative metabolism of Δ9-tetrahydrocannabinol in the rat (1991) (73)
- Enhanced binding of morphine and nalorphine to opioid delta receptor by glucuronate and sulfate conjugations at the 6-position. (1987) (73)
- Inductive effect of polychlorinated biphenyls mixture and individual isomers on the hepatic microsomal enzymes. (1978) (71)
- Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman. (1995) (71)
- Recent advances in the metabolism of cannabinoids. (1995) (68)
- Metabolism of drugs. LXIX. Studies on the urinary metabolites of morphine in several mammlian species. (1970) (68)
- Metabolism of drugs. LXX. Further study on antipyrine metabolism. (1971) (61)
- Chemical synthesis and analgesic effect of morphine ethereal sulfates. (1972) (61)
- A unique change of steroid metabolism in rat liver microsomes induced with highly toxic polychlorinated biphenyl(PCB) and polychlorinated dibenzofuran(PCDF). (1982) (61)
- Metabolism of highly persistent PCB congener, 2,4,5,2',4',5'-hexachlorobiphenyl, by human CYP2B6. (1995) (59)
- NADH-dependent O-deethylation of p-nitrophenetole with rabbit liver microsomes. (1976) (59)
- Metabolism of delta 9-tetrahydrocannabinol by cytochrome P450 isozymes purified from hepatic microsomes of monkeys. (1995) (56)
- Metabolism in vivo of 3,4,5,3',4'-pentachlorobiphenyl and toxicological assessment of the metabolite in rats. (1990) (56)
- METABOLISM OF DRUGS. XLI. THE METABOLIC FATE OF STRYCHNINE IN RABBIT LIVER. (1964) (56)
- Metabolism in vitro of 3,4,3',4'- and 2,5,2',5'-tetrachlorobiphenyl by rat liver microsomes and highly purified cytochrome P-450. (1991) (56)
- High affinity of 2,3,4,7,8-pentachlorodibenzofuran to cytochrome P-450 in the hepatic microsomes of rats (1986) (52)
- Distribution and characterization of anandamide amidohydrolase in mouse brain and liver. (1998) (51)
- Enhanced elimination of theophylline, phenobarbital and strychnine from the bodies of rats and mice by squalane treatment. (1992) (51)
- Species differences in metabolism of codeine: urinary excretion of codeine glucuronide, morphine-3-glucuronide and morphine-6-glucuronide in mice, rats, guinea pigs and rabbits. (1990) (50)
- Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme. (1991) (50)
- Toxicological assessment of highly chlorinated biphenyl congeners retained in the Yusho patients (1979) (49)
- Accumulation of polychlorinated dibenzofurans in the livers of monkeys and rats. (1980) (49)
- Metabolism of drugs. LX. The synthesis of codeine and morphine glucuronides. (1968) (49)
- Participation of cytochrome P450-2B and -2D isozymes in the demethylenation of methylenedioxymethamphetamine enantiomers by rats. (1994) (49)
- Comparison in mice of pharmacological effects of delta 8-tetrahydrocannabinol and its metabolites oxidized at 11-position. (1980) (47)
- Reduction of nitrofuran derivatives by xanthine oxidase and microsomes. Isolation and identification of reduction products. (1976) (46)
- Inductive effect on hepatic enzymes and toxicity of congeners of PCBs and PCDFs. (1985) (46)
- Sex difference in the oxidative metabolism of delta 9-tetrahydrocannabinol in the rat. (1991) (44)
- A cytochrome P450 isozyme having aldehyde oxygenase activity plays a major role in metabolizing cannabinoids by mouse hepatic microsomes. (1993) (42)
- Regiochemistry of cytochrome P450 isozymes. (1994) (40)
- Further studies on metabolism in vivo of 3,4,3',4'-tetrachlorobiphenyl in rats: identification of minor metabolites in rat faeces. (1989) (38)
- Purification and characterization of a newly identified isoform of cytochrome P450 responsible for 3-hydroxylation of 2,5,2',5'-tetrachlorobiphenyl in hamster liver. (1995) (37)
- Inhibition of hepatic microsomal cytochrome P450 by cannabidiol in adult male rats. (1990) (36)
- Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine. (1988) (35)
- Metabolism of 2,4,5,2',4',5'-hexachlorobiphenyl with liver microsomes of phenobarbital-treated dog; the possible formation of PCB 2,3-arene oxide intermediate. (1992) (35)
- Purification and characterization of seven distinct forms of liver microsomal cytochrome P-450 from untreated and inducer-treated male Wistar rats. (1985) (35)
- Cytochrome P-450 isozymes involved in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats. (1992) (33)
- cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase. (1994) (32)
- Metabolic fate of noscapine. II. Isolation and identification of novel metabolites produced by C-C bond cleavage. (1979) (31)
- Self-catalyzed inactivation of cytochrome P-450 during microsomal metabolism of cannabidiol. (1987) (30)
- Metabolic fate of noscapine. III. Further studies on identification and determination of the metabolites. (1981) (30)
- Metabolism of 2,4,5,2',4',5'-hexachlorobiphenyl (PCB153) in guinea pig. (1997) (28)
- The synthesis of codeine and morphine glucuronides. (1968) (28)
- Metabolism of strychnine in vitro. (1985) (27)
- Pharmacology and Toxicology of Major Constituents of Marijuana—On the Metabolic Activation of Cannabinoids and Its Mechanism (2003) (27)
- Purification of a phenobarbital-inducible UDP-glucuronosyltransferase isoform from dog liver which catalyzes morphine and testosterone glucuronidation. (1996) (27)
- Determination of oxycodone metabolites in urines and feces of several mammalian species. (1982) (26)
- Multiplicity of liver microsomal flavin-containing monooxygenase in the guinea pig: its purification and characterization. (1990) (26)
- Susceptibility of aromatic nitro compounds to xanthine oxidase-catalyzed reduction. (1978) (26)
- Metabolism of furazolidone by milk xanthine oxidase and rat liver 9000g supernatant: formation of a unique nitrofuran metabolite and an aminofuran derivative. (1981) (25)
- Studies on N-demethylation of methamphetamine by liver microsomes of guinea-pigs and rats: the role of flavin-containing mono-oxygenase and cytochrome P-450 systems. (1984) (25)
- Metabolic and toxicologic evaluation of 2,34,3',4'-pentachlorobiphenyl in rats and mice. (1976) (25)
- Cytochrome P-450 isozymes in metabolic activation of delta 9-tetrahydrocannabinol by rat liver microsomes. (1990) (24)
- High accumulation of 2,3,4,7,8-pentachlorodibenzofuran to hepatic microsomes of rats. (1984) (24)
- Pharmacological effects in mice of anandamide and its related fatty acid ethanolamides, and enhancement of cataleptogenic effect of anandamide by phenylmethylsulfonyl fluoride. (1999) (24)
- A constitutive form of guinea pig liver cytochrome P450 closely related to phenobarbital inducible P450b(e). (1991) (23)
- Studies of metabolic fate of a new antiallergic agent, azelastine (4-(p-chlorobenzyl)-2-[N-methylperhydroazepinyl-(4)]-1-(2H)-phthalazinone hydrochloride). (1980) (23)
- Isolation and identification of urinary metabolites of oxycodone in rabbits. (1979) (23)
- Hepatic microsomal oxygenation of aldehydes to carboxylic acids. (1990) (23)
- Metabolic fate of strychnine in rats. (1989) (22)
- Cannabielsoin as a new metabolite of cannabidiol in mammals (1991) (22)
- Hamster liver cytochrome P450 (CYP2A8) as a 4-hydroxylase for 2,5,2',5'-tetrachlorobiphenyl. (1996) (22)
- Mechanism for inhibitory effect of cannabidiol on microsomal testosterone oxidation in male rat liver. (1988) (22)
- Metabolism of drugs. LXXX. The metabolic fate of nitrofuran derivatives. 3. Studies on enzymes in small intestinal mucosa of rat catalyzing degradation of nitrofuran derivatives. (1973) (21)
- Metabolism in vitro of sulindac. Sulfoxide-reducing enzyme systems in guinea pig liver. (1980) (21)
- Enzymic cis-trans isomerization of nitrofuran derivatives: isomerizing activity of xanthine oxidase, lipoyl dehydrogenase, DT-diaphorase and liver microsomes. (1979) (21)
- ISOLATION AND IDENTIFICATION OF THE METABOLITE OF N-(5-NITRO-2-FURFURYLIDENE)-3-AMINO-2-OXAZOLIDONE (FURAZOLI-DONE) (1978) (21)
- Synthesis and pharmacological activity of a phosphate ester of .DELTA.8-tetrahydrocannabinol (1978) (21)
- Stimulating effect of activated charcoal beads on fecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats (1986) (21)
- Analysis and pharmacotoxicity of feruloyltyramine as a new constituent and p-coumaroyltyramine in Cannabis sativa L. (1991) (20)
- Identification of cannabielsoin, a new metabolite of cannabidiol formed by guinea-pig hepatic microsomal enzymes, and its pharmacological activity in mice. (1988) (20)
- Metabolism of drugs. LIX. A new metabolite of antipyrine. (1968) (20)
- Major role of the CYP2C isozymes in deamination of amphetamine and benzphetamine: evidence for the quinidine-specific inhibition of the reactions catalysed by rabbit enzyme. (1997) (19)
- Brain microsomal oxidation of Δ8- and Δ9-tetrahydrocannabinol (1988) (19)
- Metabolism of drugs. XXXV. Metabolic fate of meprobamate. (3). A new metabolic pathway of carbamate group--the formation of meprobamate N-glucuronide in animal body. (1963) (19)
- Oxygen--insensitive nitrofuran reductases in Salmonella typhimurium TA100. (1982) (18)
- Involvement of cytochrome b5 in the metabolism of tetrachlorobiphenyls catalyzed by CYP2B1 and CYP1A1. (1996) (18)
- In vivo and in vitro metabolism of cannabidiol monomethyl ether and cannabidiol dimethyl ether in the guinea pig: on the formation mechanism of cannabielsoin-type metabolite from cannabidiol. (1990) (18)
- [Studies on distribution, excretion and subacute toxicity of squalane in dogs]. (1989) (17)
- Effect of cytochrome P450 inducers on liver microsomal metabolism of tetrachlorobiphenyls in rats, guinea pigs and hamsters. (1995) (17)
- The pharmacological activity of cannabinol and its major metabolite, 11-hydroxycannabinol. (1987) (17)
- A rabbit liver constitutive form of cytochrome P450 responsible for amphetamine deamination. (1989) (17)
- Synthesis and pharmacological activities in mice of halogenated delta 9-tetrahydrocannabinol derivatives. (1998) (17)
- Metabolism in vivo of the tropane alkaloid, scopolamine, in several mammalian species. (1991) (16)
- Microsomal aldehyde oxygenase (MALDO): purification and characterization of a cytochrome P450 isozyme responsible for oxidation of 9-anthraldehyde to 9-anthracenecarboxylic acid in monkey liver. (1996) (16)
- Binding of nitrofuran derivatives to nucleic acids and protein. (1977) (16)
- Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by mouse hepatic microsomes. (1988) (16)
- Enhanced faecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats by a long-term treatment with activated charcoal beads. (1988) (16)
- Inhibitory effect of cannabidiol hydroxy-quinone, an oxidative product of cannabidiol, on the hepatic microsomal drug-metabolizing enzymes of mice. (1991) (16)
- Regiochemical differences in cytochrome P450 isozymes responsible for the oxidation of methylenedioxyphenyl groups by rabbit liver. (1992) (16)
- Deamination of amphetamines by cytochromes P450: studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes. (1997) (16)
- Identification of in vitro metabolites of 2,4,6,2',4',6'-hexachlorobiphenyl from phenobarbital-treated dog liver microsomes. (1993) (15)
- Microsomal alcohol oxygenase: purification and characterization of a cytochrome P450 responsible for oxidation of 7-hydroxy-delta 8-tetrahydrocannabinol to 7-oxo-delta 8-tetrahydrocannabinol in guinea pig liver. (1997) (15)
- Effects of several factors on urinary excretion of methamphetamine and its metabolites in rats. (1986) (15)
- Enzymatic oxidation of 7-hydroxylated delta 8-tetrahydrocannabinol to 7-oxo-delta 8-tetrahydrocannabinol by hepatic microsomes of the guinea pig. (1988) (15)
- Microsomal oxygenase catalyzed oxidation of 11-hydroxy-Δ8-tetrahydrocannabinol to 11-oxo-Δ8-tetrahydrocannabinol (1979) (15)
- 9 alpha, 10 alpha-epoxyhexahydrocannabinol formation from delta 9-tetrahydrocannabinol by liver microsomes of phenobarbital-treated mice and its pharmacological activities in mice. (1983) (15)
- Catalytic activity of cytochrome P450 isozymes purified from rat liver in converting 11-oxo-Δ8-tetrahydrocannabinol to Δ8-tetrahydrocannabinol-11-oic acid (1991) (15)
- Purification and characterization of two forms of chicken liver cytochrome P-450 induced by 3,4,5,3',4'-pentachlorobiphenyl. (1988) (15)
- Isolation and identification of urinary metabolites of AF-2 (3-(5-nitro-2-furyl)-2-(2-furyl)acrylamide) in rabbits. (1977) (14)
- Cis-trans isomerization of nitrofuran derivatives by xanthine oxidase. (1976) (14)
- METABOLISM OF DRUGS. L. THE IN VITRO STUDY ON METABOLISM OF BRUCINE AND 4-SUBSTITUTED VERATROLES. (1964) (14)
- Mechanisms for stimulated fecal excretion of 2,3,4,7,8-pentachlorodibenzofuran in rats by treatment with squalane and liquid paraffin (1987) (14)
- Difference in epoxides formation and their further metabolism between delta 9- and delta 8-tetrahydrocannabinols by human liver microsomes. (1984) (14)
- Metabolism of 2,3',4',5-tetrachlorobiphenyl by cytochrome P450 from rats, guinea pigs and hamsters. (1998) (14)
- Chemical analysis and toxicity of polychlorinated biphenyls and dibenzofurans in relation to yusho. (1982) (14)
- Sex difference in hepatic microsomal aldehyde oxygenase activity in different strains of mice. (1992) (14)
- Metabolic fate of fenetylline in rat and man. (1988) (14)
- Synthesis and pharmacological evaluation in mice of halogenated cannabidiol derivatives. (1999) (14)
- Human liver microsomal oxidation of delta 8-tetrahydrocannabinol. (1983) (13)
- Comparison of pharmacological effects of tetrahydrocannabinols and their 11-hydroxy-metabolites in mice. (1990) (13)
- Species difference in metabolism of strychnine with liver microsomes of mice, rats, guinea pigs, rabbits and dogs. (1990) (13)
- Synthesis of 8α, 9α- and 8β, 9β-Epoxyhexahydrocannabinols (1981) (13)
- RELATIONSHIP BETWEEN BIOLOGICAL ACTIVITIES AND ENZYMATIC REDUCTION OF NITROFURAN DERIVATIVES (1978) (13)
- In vitro and in vivo interactions of delta 8-tetra-hydrocannabinol and its metabolites with hepatic microsomal drug metabolizing enzyme systems of mice. (1981) (13)
- Mode of reactions between xanthine oxidase and aromatic nitro compounds. (1981) (13)
- 3,4,5,3',4'-Pentachlorobiphenyl as a useful inducer for purification of rat liver microsomal cytochrome P448. (1979) (12)
- A Colorimetric Method for the Determination of Cannabinoids with Fast Blue BB Salt (1979) (12)
- Synthesis and pharmacological effects in mice of halogenated cannabinol derivatives. (1995) (12)
- Effects of two cannabinoids on hepatic microsomal cytochrome P-450. (1986) (12)
- Metabolism of drugs. LI. The metabolic fate of alkylaryl ethers in rabbits. (1966) (12)
- Purification and characterization of a morphine UDP-glucuronyltransferase isoform from untreated rat liver. (1993) (12)
- A new metabolite of 2,4,3',4'-tetrachlorobiphenyl in rat feces. (1992) (12)
- Synthesis and analgesic effect of normorphine-3- and -6-glucuronides. (1989) (12)
- Metabolism of drugs. LXII. Isolation and identification of morphine glucuronides in urine and bile of rabbits. (1969) (11)
- Studies on oxygen-insensitive nitrofuran reductase in Escherichia coli B/r. (1981) (11)
- Chemical reactivity of morphine and morphine-6-conjugates and their binding to rat brain. (1976) (11)
- Toxicological evaluation of sulfur-containing metabolites of 2,5,2′,5′-tetrachlorobiphenyl in rats (1985) (11)
- Tissue-specific expression, induction, and inhibition through metabolic intermediate-complex formation of guinea pig cytochrome P450 belonging to the CYP2B subfamily. (1992) (11)
- Pharmacological activities in the mouse of delta 9-tetrahydrocannabinol metabolites oxidized at the 8-position. (1985) (11)
- Formation of p-hydroxycocaine from cocaine by hepatic microsomes of animals and its pharmacological effects in mice. (1993) (11)
- [Sex difference in the effects of delta 9-tetrahydrocannabinol and cannabidiol on pentobarbital-induced sleeping time and hepatic microsomal drug metabolizing enzyme systems in mice]. (1983) (11)
- Modification of the gluconeogenesis is not involved in the co-planar PCB toxicity in highly sensitive guinea pigs (1993) (11)
- Metabolism of drugs. LXXVI. The metabolic fate of prolintane in rabbits. (1972) (11)
- Purification and characterization of a novel 46.5-kilodalton esterase from mouse hepatic microsomes. (1993) (11)
- A novel metabolite of oxycodone in the urine of rabbits. (1982) (11)
- Mouse hepatic microsomal oxidation of aliphatic aldehydes (C8 to C11) to carboxylic acids. (1992) (11)
- Development of tolerance and cross-tolerance to the cataleptogenic effects of delta 8-tetrahydrocannabinol and 11-hydroxy-delta 8-tetrahydrocannabinol in mice. (1983) (10)
- Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats. (1993) (10)
- Metabolism of 3,5,3',5'-tetrachlorobiphenyl by rat liver microsomes and purified P4501A1. (1994) (10)
- Studies on rat liver cytochrome P-450s involved in the metabolism of antipyrine: phenobarbital- and 3-methylcholanthrene-inducible isozymes possessing 4-hydroxylase activity. (1986) (10)
- [Improved method of the synthesis of 3, 4, 5, 3', 4'-pentachlorobiphenyl (author's transl)]. (1979) (10)
- Site-selective oxidation of strychnine by phenobarbital inducible cytochrome P-450. (1991) (10)
- Effect of morphine and its conjugates on the isolated ileal preparation of guinea-pig. (1977) (10)
- Enhancement of sulfanilamide N4-hydroxylase activity in kidney and liver microsomes of rats by pretreatment with 3-methylcholanthrene type-polychlorinated biphenyl. (1982) (10)
- Metabolism of drugs. XVI. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 6. Studies on the reduction of 3-keto-MHB (5-(3-oxo-1-cyclohexenyl)-3,5-dimethylbarbituric acid) and on pharmacological activity of the biotransformation products of methylhexabital from the (1958) (10)
- Comparison of DT-diaphorases purified from the liver cytosol of untreated, and 3,4,5,3',4'-pentachlorobiphenyl- and 3-methylcholanthrene-treated rats. (1987) (10)
- Enzymic reduction of N-hydroxyamphetamine: the role of electron transfer system containing cytochrome b5. (1988) (10)
- Guinea Pig Liver Cytochrome P450 Responsible for 3-Hydroxylation of 2,5,2′,5′-Tetrachlorobiphenyl (1998) (10)
- Metabolism of drugs. LXXII. Synthesis of nalorphine-3- and -6-glucuronide and identification of urinary metabolites of nalorphine in rabbits. (1970) (10)
- Difference in tolerance development to hypothermia and pentobarbital-induced sleep prolongating effect of 11-hydroxy-Δ8-tetrahydrocannabinol and 11-oxo-Δ8-tetrahydrocannabinol in mice (1982) (10)
- IDENTIFICATION AND DETERMINATION OF 11-OXO-Δ8-TETRAHYDROCANNABINOL AS AN INTERMEDIATE METABOLITE OF Δ8-TETRAHYDROCANNABINOL IN THE MOUSE BRAIN AND LIVER (1980) (10)
- [Metabolism of drugs. LXXI. The study on aminopyrine metabolism]. (1970) (10)
- Cannabidiol metabolism revisited: tentative identification of novel decarbonylated metabolites of cannabidiol formed by human liver microsomes and recombinant cytochrome P450 3A4 (2019) (9)
- On the Structure of Morphine-6-glucuronide in a Solid State (1970) (9)
- Induction of bilirubin UDP-glucuronyltransferase and CYP4A1 P450 by co-planar PCBs: Different responsiveness of guinea pigs and rats (1994) (9)
- Suppression of liver microsomal drug-metabolizing enzyme activities in adult female rats pretreated with cannabidiol. (1993) (9)
- SELECTIVE INDUCTION OF RAT LIVER MICROSOMAL CYTOCHROME P-448 BY 3, 4, 5, 3', 4'-PENTACHLOROBIPHENYL AND ITS EFFECT ON LIVER MICROSOMAL DRUG METABOLISM (1979) (9)
- Metabolism of drugs. LVI. The metabolic fate of phenacetylurea. (1967) (9)
- Species difference in codeine uridine diphosphate-glucuronyltransferase activity of liver microsomes. (1990) (9)
- Metabolism of drugs. LXXIX. The metabolic fate of nitrofuran derivatives. 2. Degradation by small intestinal mucosa and absorption from gastrointestinal tract. (1973) (9)
- Identification and Determination of Cannabinoids in Commercially Available Cannabis Seeds (1990) (8)
- Decomposition of 4-Nitropyridine (1952) (8)
- Major cytochrome P450 enzyme responsible for oxidation of secondary alcohols to the corresponding ketones in mouse hepatic microsomes. Oxidation of 7-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol. (1998) (8)
- Involvement of a novel mouse hepatic microsomal esterase, ES46.5K, in the hydrolysis of phthalate esters. (1997) (8)
- Mouse hepatic microsomal enzyme that catalyzes oxidation of 11-oxo-delta 8-tetrahydrocannabinol to delta 8-tetrahydrocannabinol-11-oic acid. (1991) (8)
- Further studies of sulfoxide-reducing enzyme system. (1981) (8)
- Mechanism of biological formation of cannabielsoin from cannabidiol in the guinea-pig, mouse, rat and rabbit. (1989) (8)
- Metabolism of drugs. XIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 5. Further studies on isolation, characterisation, and identification of biotransformation products of the drug excreted in the urine of rabbit. (1957) (8)
- Synthesis of delta 8-tetrahydrocannabinol glucuronide and sulfate, and their metabolic disposition in rats. (1979) (8)
- Metabolism and nephrotoxicity of phenacetin and sulfanilamide. (1985) (8)
- Competitive inhibition of delta8-tetrahydrocannabinol and its active metabolites for cannabinoid receptor binding. (1998) (8)
- [Stimulating effect of squalene on fecal excretion of a high toxic 2,3,4,7,8-pentachlorodibenzofuran (PenCDF) in rats]. (1985) (8)
- SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF A PHOSPHATE ESTER OF Δ8‐TETRAHYDROCANNABINOL (1979) (8)
- Metabolism of drugs. VI. The metabolic fate of methylhexabital (5-cyclohexenyl-3, 5-dimethylbarbituric acid). 2. On the chromic oxidation of methylhexabital and normethylhexabital (5-cyclohexenyl-5-methylbarbituric acid). (1956) (8)
- Formation of carbon monoxide during mouse hepatic microsomal oxidative metabolism of cannabidiol; identification and determination. (1995) (8)
- Fluorometric assay of microsomal aldehyde oxygenase activity: 9-anthraldehyde as a substrate. (1991) (7)
- In vitro metabolic formation of a new metabolite, 6 beta-hydroxymethyl-delta 9-tetrahydrocannabinol from cannabidiol through an epoxide intermediate and its pharmacological effects on mice. (1993) (7)
- [Preliminary studies on the experimental PCB poisoning in rhesus monkeys (author's transl)]. (1979) (7)
- 8α,9α-Epoxyhexahydrocannabinol formation from Δ8-tetrahydrocannabinol by mouse liver microsomes (1982) (7)
- 3,4,5-Trimethoxyphenylacetaldehyde, an intermediate metabolite of mescaline, is a substrate for microsomal aldehyde oxygenase in the mouse liver. (1995) (7)
- Unique induction of cytochrome P-450 isozymes in rat liver microsomes by treatment with 3,4,5,3',4'-pentachlorobiphenyl and its effect on testosterone metabolism. (1985) (7)
- Purification and characterization of two forms of 2,3,4,7,8-pentachlorodibenzofuran-inducible cytochrome P-450 in hamster liver. (1990) (7)
- Metabolism of Drugs. XXXII. The Metabolic Fate of Secobarbital [5-Allyl-5-(1-methylbutyl) barbituric Acid]. (1963) (7)
- Change in hypothermia and catalepsy induced by cannabinoids or morphine in mice tolerant to these substances. (1987) (7)
- Metabolism of drugs. 28. Metabolic fate of meprobamate. (1). Isolation and characterization of metabolites. (1962) (7)
- Metabolism of drugs. LXVII. The metabolic fate of isoprophenamine. (1970) (7)
- Further studies on carbamate N-glucuronide formation in animal body. (1963) (7)
- Possible implication of a aldehyde metabolite in aminopyrine allergy. (1972) (7)
- Studies on N-demethylation of methamphetamine by means of purified guinea-pig liver flavin-containing monooxygenase. (1987) (7)
- A novel metabolite of strychnine, 22-hydroxystrychnine. (1991) (7)
- A new metabolite of methamphetamine; evidence for formation of N-[(1-methyl-2-phenyl)ethyl]ethanimine N-oxide. (1987) (7)
- Metabolism of drugs. 73. The metabolic fate of nitrofuran derivatives. 1. Studies on the absorption and excretion. (1971) (7)
- NADH-dependent O-demethylation of p-nitroanisole with rabbit liver microsomes. (1977) (7)
- Metabolic disposition of delta 8-tetrahydrocannabinol and its active metabolites, 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol, in mice. (1981) (7)
- Purification of a cytochrome P450 isozyme belonging to a subfamily of P450 IIB from liver microsomes of guinea pigs. (1990) (7)
- Detection of morphine in urine. II. An improved method by thin-layer chromatography utilizing potassiuum platinum iodide as the reagent for both coloration and fluorescence. (1966) (7)
- [Studies on distribution and excretion of squalane in dogs administered for 2 weeks]. (1991) (6)
- Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats. (1983) (6)
- Metabolism of prolintane in rats and the effect of prolintane metabolites on general activities in mice. (1974) (6)
- Metabolism of drugs. II. The metabolic fate of ethylhexabital (5-cyclohexenyl-5-ethylbarbituric acid). (1954) (6)
- [Effect of a coplanar PCB on lipid metabolism: the remarkable difference between rats and guinea pigs]. (1995) (6)
- Cross-tolerance to the hypothermic effect of Δ8-tetrahydrocannabinol 11-hydroxy-Δ8-tetrahydrocannabinol and chlorpromazine in the mouse (1985) (6)
- Substrate specificity of guinea pig liver flavin-containing monooxygenase for morphine, tropane and strychnos alkaloids. (1990) (6)
- Studies on enzymatic reduction of aliphatic nitro compounds: reductive dimerization of beta-nitrostyrene and 1-nitro-4-phenylbutadiene. (1982) (6)
- Metabolism of butyl p-nitrophenyl ether in vitro with rabbit liver preparations. (1978) (6)
- Metabolism of drugs. LVII. Isolation, characterization and identification of p-nitrophenoxy acetic acid, a metabolite of butyl p-nitrophenyl ether in rats, mice and guinea pigs. (1967) (6)
- Metabolism of drugs. LXXXI. Further studies on metabolism of prolintane in rabbits. (1974) (6)
- The metabolism of phenyl o-(2-N-morpholinoethoxy)-phenyl ether hydrochloride in the rabbit and rat. (1975) (6)
- METABOLISM OF DRUGS. XXXIX. FURTHER STUDIES ON CARBAMATE N-GLUCURONIDE FORMATION IN ANIMAL BODY. (1963) (6)
- Brain microsomal oxidation of delta 8- and delta 9-tetrahydrocannabinol. (1988) (6)
- Potentiation of physical dependence by conjugation at the 6-position of nalorphine. (1984) (6)
- Metabolic formation of dimethylamine and methylamine from basic drugs containing N-methyl group: a newly established chromatographic assay and its application to the determination of deaminase activity. (1993) (6)
- STUDIES ON METABOLIC ACTIVATION OF NITROFURANS : FORMATION OF ACTIVE METABOLITES AND THEIR BINDING TO CYSTEINE AND GLUTATHIONE (1978) (6)
- Properties of nitrofuran reductases from Escherichia coli B/r. (1983) (6)
- Identification and determination of 8α,9α-epoxyhexahydrocannabinol as a metabolite of δ8-tetrahydrocannabinol of mice in vitro (1982) (5)
- Metabolism of drugs. VII. The metabolic fate of methylhexabital (5-cyclohexenyl-3, 5-dimethylbarbituric acid). 3. Isolation, characterization, and identification of metabolic products of methylhexabital. (1956) (5)
- Rat liver DT-diaphorase as a nitroso-reductase. (1990) (5)
- Reduced nicotinamide adenine dinucleotide-dependent O-deethylation of p-nitrophenetole with rabbit liver microsomes. II. Involvement of cytochrome b5. (1977) (5)
- The properties of UDP-glucuronyltransferase for cannabinoids in rat liver microsomes. (1983) (5)
- Suppressive effect of interferon inducer, polyriboinosinic acid-polyribocytidylic acid on induction of uridine diphosphate-glucuronyltransferases and monooxygenases in liver microsomes of rats. (1986) (5)
- Cannabinoid metabolite interacts with benzodiazepine receptor (1992) (5)
- [Synthesis of 2-chloro and 1,4,8-trichlorodibenzofuran and their effect on the growth of mice and on the liver microsomal drug metabolizing enzyme systems of rats (author's transl)]. (1977) (5)
- Synthesis and pharmacological activity of sulfate conjugates at 6-position of N-substituted normorphine derivatives. (1991) (5)
- Detection of morphine in urine. (1966) (5)
- Metabolism of drugs. XXIX. Metabolic fate of meprobamate. 2. Further studies on the structure of the metabolites. (1962) (5)
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- Unique features of subcellular distribution of 2,3,4,7,8-pentachlorodibenzofuran in rat liver (1987) (4)
- Sulphotransferase-dependent dehydration of atropine and scopolamine in guinea pig. (1994) (4)
- Metabolism of drugs-LXV. Studies on the urinary conjugated metabolites of codeine. (1970) (4)
- Effect of repeated administration of 11-hydroxy-delta 8-tetrahydrocannabinol, an active metabolite of delta 8-tetrahydrocannabinol, on the hepatic microsomal drug-metabolizing enzyme system of mice. (1986) (4)
- Interactions of cannabis extract, Δ9-tetrahydrocannabinol and 11-hydroxy-Δ8-tetrahydrocannabinol with methamphetamine in mice (1988) (4)
- Metabolism of drugs—XLVIII. the study of selective demethylation of brucine in vivo (1964) (4)
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- Changes in 5-HT receptor binding induced by tetrahydrocannabinol metabolites in bovine cerebral cortex (1996) (4)
- Pharmacological activity of 8α,9α- and 8β,9β-epoxyhexahydrocannabinol in mice (1981) (4)
- The Occurrence of (ω-1)-Hydroxylation as the Major Metabolism of Alkylaryl Ethers in Rabbits (1964) (4)
- Metabolism of drugs. XVIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3,5 dimethylbarbituric acid). 8. The quantitative determination of main biotransformation products of methylhexabital in the urine of rabbits by ultra-violet spectrophotometry. (1958) (4)
- Metabolism of drugs. XVII. Metabolic fate of methylhexabital (5-cyclohexenyl-3,5-dimethylbarbituric acid). 7. Separation and identification of biotransformation products of methylhexabital in the urine of rabbits by paper chromatography. (1958) (4)
- Effect of co-administration of interferon inducer, polyriboinosinic acid-polyribocytidylic acid, with SKF 525-A on hepatic drug metabolizing enzymes of rats. (1986) (4)
- Metabolism of an antiallergic agent, azelastine (4-(p-chlorobenzyl)-2-[N-methylperhydroazepinyl-(4)]-1-(2H)-p hthalazin one hydrochloride) in rats and guinea pigs. (1984) (4)
- Metabolism and Pharmacology of Marihuana Constituents (1982) (3)
- Formation of similar species to carbon monoxide during hepatic microsomal metabolism of cannabidiol on the basis of spectral interaction with cytochrome P-450. (1988) (3)
- [Acute toxicity, inductive effects of liver enzymes and distribution in the liver of 1,2,3,7,8-pentachlorodibenzo-p-dioxin in rats]. (1991) (3)
- Metabolism of drugs. LII. Enzymatic study on secobarbital metabolism. (1967) (3)
- Metabolism of drugs. III. The metabolic fate of methylhexabital (5-cyclohexenyl-3, 5-dimethyl-barbituric acid). (1955) (3)
- Accumulation, excretion and effects on hepatic enzymes of polychlorinated quaterphenyl congeners in rats. (1985) (3)
- Immunochemical characterization of a cytochrome P450 isozyme and a protein purified from liver microsomes of male guinea pigs and their roles in the oxidative metabolism of delta 9-tetrahydrocannabinol by guinea pig liver microsomes. (1992) (3)
- Reduction of methyl 5-nitro-2-furoate by xanthine oxidase: an evidence for hydroxylaminofuran formation. (1982) (3)
- Metabolism of Drugs. XXXVI. The Metabolic Fate of Thiamylal[5-Allyl-5-(1-methylbutyl)-2-thiobarbituric Acid]. (2). (1963) (3)
- Catalytic activity of cytochrome P450 isozymes purified from rat liver in converting 11-oxo-delta 8-tetrahydrocannabinol to delta 8-tetrahydrocannabinol-11-oic acid. (1991) (3)
- [Stimulation of fecal excretion of the etiological compounds of yusho in rats]. (1987) (3)
- [Acute toxicity and inductive effect on liver enzymes of 3,4,5,3',4'-pentachlorobiphenyl in guinea pigs (author's transl)]. (1981) (3)
- Analysis of Nitrogen Containing Compounds, p-Coumaroyltyramine and Feruloyltyramine, for Discrimination of Cannabis Seeds by HPLC (1997) (3)
- Spectral interaction of 11-hydroxy-delta-8-tetrahydrocannabinol with rabbit and rat liver microsomal cytochrome P-450. (1980) (3)
- Cis-trans isomerization of a nitrofuran AF-2 by rat liver microsomal preparations. (1984) (3)
- Cross‐tolerance development to the prolongation of pentobarbitone‐induced sleep by Δ8‐tetrahydrocannabinol and 11‐hydroxy‐Δ8‐tetrahydrocannabinol in mice (1987) (3)
- Metabolism of drugs. VIII. The metabolic fate of methylhexabital (5-cyclohexenyl-3, 5-dimethylbarbituric acid). 4. Ultraviolet and infrared absorption spectra of the metabolites of MHB and related compounds. (1956) (2)
- METABOLIC DISPOSITION OF 8α, 9α-AND 8β, 9β-EPOXYHEXAHYDROCANNABINOLS IN THE MOUSE (1984) (2)
- Pharmacological activity of side chain hydroxylated metabolites of Δ9-tetrahydrocannabinol in mice (1986) (2)
- Measurement of urinary thiamine propyl disulfide metabolites as an index of liver function. (1984) (2)
- Stereospecific hydrolysis of 8α,9α- and 8β,9β-epoxyhexahydrocannabinols in the mouse in vivo and in vitro (1985) (2)
- SULFOXIDE-REDUCING ENZYME SYSTEMS (1980) (2)
- UDP-GLUCURONYLTRANSFERASES IN MICE BRAIN AND THE INDUCIBILITY (1982) (2)
- Mechanism of hepatic microsomal oxidation of 11-hydroxy-delta 8-tetrahydrocannabinol to 11-oxo-delta 8-tetrahydrocannabinol. Evidence for hydration of the aldehyde formed. (1992) (2)
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- Role of cytochrome b5 in the oxidative metabolism of polychlorinated biphenyls catalyzed by cytochrome P450. (1996) (2)
- EFFECT OF ENDOTOXIN ON INDUCTION OF MONOOXYGENASES AND UDP-GLUCURONYLTRANSFERASES IN RAT HEPATIC MICROSOMES (1985) (2)
- MECHANISM OF TOXICITY PRODUCED BY 3-METHYLCHOLAN-THRENE-TYPE PCBs (1) (1981) (2)
- Metabolism of drugs. LXIV. Species differences of metabolism of phenacetylurea. (1969) (2)
- Decreased urinary excretion of thiamine propyl disulfide metabolites in patients with liver disease. (1982) (2)
- Tolerance development of 8α,9α- and 8β,9β- epoxyhexahydrocannabinols in the mouse (1983) (2)
- Formation of novel nitrofuran metabolites in xanthine oxidase-catalyzed reduction of methyl 5-nitro-2-furoate. (1984) (2)
- [Synthesis and pharmacological effect of morphine phosphate esters (author's transl)]. (1973) (2)
- The formation mechanism of cannabielsoin from cannabidiol with guinea pig hepatic microsomal enzymes (1987) (2)
- Studies on the metabolic relationship between alkyl carbamates and alkyl N-hydroxycarbamates in rats. (1980) (2)
- Synthesis and Pharmacological Activities in Mice of Halogenated Δ9-Tetrahydrocannabinol Derivatives. (1999) (2)
- In vivo effects of tetrahydrocannabinols and their eight monooxygenated metabolites of the hepatic microsomal drug-metabolizing enzyme systems of mice. (1987) (2)
- UDP-glucuronyltransferase activities of rabbit liver microsomes for cannabinoids. (1980) (2)
- A Novel Metabolite, an Oxepin Formed from Cannabidiol with Guinea‐pig Hepatic Microsomes (1995) (2)
- [Metabolism of drugs. LXVI. Studies on the metabolic fate of pantethine]. (1970) (2)
- In vivo metabolism of 11-hydroxy-delta-tetrahydrocannabinol to two carboxylic acids and the effects of SKF 525-A, cobaltous chloride and phenobarbital on their formation in rats. (1980) (2)
- [Metabolism of drugs. 58. Metabolism of butylaminoantipyrine]. (1968) (2)
- [The metabolism of drugs. 68. Metabolic fate of metaproterenol. (1)]. (1970) (2)
- Determination of urinary metabolites of thiamine propyl disulfide in humans. (1982) (2)
- Difference in tolerance development of hypothermia and pentobarbital-induced sleep prolongating effect of 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol in mice. (1982) (2)
- [Metabolism in vivo of 2, 4, 6, 2', 4', 6'-hexachlorobiphenyl in dog and partial characterization of cytochrome P-450 isozyme responsible for biotransformation of the congener]. (1993) (1)
- Characterization of Mouse Hepatic Microsomal Enzyme that Catalyzes Oxidation of Cannabinol at the 11-Position. (1992) (1)
- Involvement of a Novel Mouse Hepatic Esterase (ES46.5K) in the Hydrolysis of Phthalate Esters (Proceedings of the 21st Symposium on Toxicology and Environmental Health) (1996) (1)
- THE CONTRIBUTION OF 6-ACETYL GROUP TO PHARMACOLOGICAL EFFECTS OF 6-ACETYLMORPHINE, AN ACTIVE METABOLITE OF HEROIN (1984) (1)
- Studies on enzymic cis-trans isomerization of nitrothiophene and nitrobenzene derivatives. (1980) (1)
- Forensic toxicology of morphine and heroin. (1986) (1)
- [Tissue distribution, inductive effect on liver enzymes and acute toxicity of 2,3,4,7,8-pentachlorodibenzofuran in Golden Syrian hamsters]. (1989) (1)
- [Acute toxicity and inductive effect on liver enzyme activities of 3,4,5,3',4'-pentachlorobiphenyl in chickens]. (1985) (1)
- Stimulating Effect of Liquid Paraffin and Cholestyramine on Fecal Excretion of 2, 3, 4, 7, 8-Pentachlorodibenzofuran in Rats (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations) (1986) (1)
- Effect of liver S9 from 3,4,5,3',4'-pentachlorobiphenyl-pretreated rats on the mutagenic activity of the various carcinogens toward Salmonella typhimurium TA 98. (1985) (1)
- [The metabolism of drugs. LXXIV. Metabolic fate of metaproterenol. 2]. (1971) (1)
- METABOLISM OF DRUGS. XLIX. THE STUDY OF SELECTIVE DEMETHYLATION OF 4-ACETAMINO- AND 4-NITRO-VERATROLES IN VIVO. (1964) (1)
- THE MECHANISM OF N-DEMETHYLATION OF METHAMPHETAMINE BY LIVER MICROSOMES : THE ROLE OF FLAVIN CONTAINING MONOOXYGENASE AND CYTOCHROME P-450 SYSTEMS (1983) (1)
- Cross-tolerance development to the prolongation of pentobarbitone-induced sleep by delta 8-tetrahydrocannabinol and 11-hydroxy-delta 8-tetrahydrocannabinol in mice. (1987) (1)
- Metabolism of amphetamine, methamphetamine and the related compounds. Biochemical aspects. (1989) (1)
- [Our drug metabolism studies during the last four decades]. (1991) (1)
- Metabolism of drugs. LXXV. The enzymatic degradation of isoprophenamine. (1971) (1)
- Enzymatic Hydroxylation of Tetrachlorobiphenyls in Rats (1992) (1)
- Specific expression of ES46.5K, a novel microsomal esterase, in the mouse liver and its catalytic activity for xenobiotic amide and esters. (1997) (1)
- [Metabolism of drugs. 53. On the metabolic fate of carbamate N-glucuronides]. (1966) (1)
- Pharmacological activity of Δ8-tetrahydrocannabinol derivatives oxidized at the 4'-position in mice (1990) (1)
- Anticonvulsant effect of 8α,9α- and 8β,9β-epoxyhexahydrocannabinols on pentylenetetrazol-induced seizures in the mouse (1982) (1)
- A POTENTIATION OF PHYSICAL DEPENDENCE BY 6-CONJUGATION OF MORPHINE AND NALORPHINE (1981) (1)
- Cytochrome P450 isozymes involved in metabolic activation of Δ9-tetrahydro-cannabinol by rat livef microsomes (1990) (1)
- Reconstitution of Apo-DT-diaphorase with flavin-adenine dinucleotide. (1986) (1)
- MECHANISM OF TOXICITY PRODUCED BY 3-METHYLCHOLANTHRENE-TYPE PCBS (2) : EFFECTS OF PCBS AND RELATED COMPOUNDS ON THE METABOLISM OF STEROIDS (1981) (1)
- Metabolism of drugs. LXXXVI. The metabolic fate of nitrofuran derivatives. (4). The portal absorption of nitrofuran derivatives and the absorption rate as a function of age in rats. (1975) (1)
- [Quantitative analysis and pharmaco-toxicity of cannabinoids in commercially available cannabis seeds]. (1998) (1)
- [Synthesis of 14C-2,3,4,7,8-pentachlorodibenzofuran]. (1983) (1)
- [Enhancement of reduction activity of 4-nitroquinoline N-oxide in rats pretreated with 3-methylcholanthrene-type PCB]. (1983) (1)
- SUPPRESSION BY INTERFERON INDUCER ON INDUCTION OF MONOOXYGENASES AND UDP-GLUCURONYLTRANSFERASES IN LIVER MICROSOMES OF RATS (1984) (1)
- MORPHINE CONJUGATES AS PHARMACOLOGICALLY ACTIVE METABOLITES (1980) (1)
- METABOLIC ACTIVATION OF CANNABIDIOL BY HEPATIC MICROSOMES. COMPLEX FORMATION WITH CYTOCHROME P-450 (1987) (0)
- Metabolic Reaction of Tolualdehydes by Microsomal Aldehyde Oxygenase (MALDO) in Lung (Proceedings of the 19th Symposium on Toxicology and Environmental Health) (1994) (0)
- CIS-TRANS ISOMERIZATION OF NITROFURAN AF-2 BY RAT LIVER MICROSOMAL PREPARATIONS (1985) (0)
- Δ8-Tetrahydrocannabinol p-quinone as an air oxidation product of Δ8-tetrahydrocannabinol and its biological and pharmacological effects in mice (1997) (0)
- Mechanism of Pulmonary Cytochrome P450 Inactivation by Tolualdehydes, Active Metabolites of Xylenes (Proceedings of the 22nd Symposium on Toxicology and Environmental Health) (1997) (0)
- SUPPRESSION OF THE INDUCTION OF RAT LIVER MONOOXYGENASES AND UDP-GLUCURONYLTRANSFERASES BY HEMATIN AND COBALTOUS CHLORIDE (1983) (0)
- Involvement of Microsomal Aldehyde Oxygenase (MALDO) in the Metabolism of Aliphatic Aldehydes in the Mouse Liver (Proceedings of the 20th Symposium on Toxicology and Environmental Health) (1995) (0)
- Studies on Metabolism and Toxicity of Organic Solvents, Toluene and Related Compounds : Metabolism of Benzaldehydes by Microsomal Aldehyde Oxygenase (MALDO) (Proceedings of the 18th Symposium on Toxicology, and Environmental Health) (1993) (0)
- METABOLIC CONVERSION OF Δ^8-TETRAHYDROCANNABINOL (Δ^8-THC) TO Δ^8-THC-11-OIC ACID AND ITS PHARMACOLOGICAL IMPLICATIONS (1980) (0)
- Mechanism of Inhibitory Effects of Cannabidiol and Cannabidiol Hydroxy-quinone on the Hepatic Microsomal Drug-Metabolizing Enzymes in Mice (Proceedings of the 23rd Symposium on Toxicology and Environmental Health) (1998) (0)
- Microsomal Aldehyde Oxygenase (MALDO) for Tolualdehydes, Active Metabolites of Xylenes, in the Mouse Liver and Lung (1998) (0)
- Acute Toxicity and Inductive Effect on Liver Enzymes of 3,4,5,3', 4'-Pentachlorobiphenyl in Chickens (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology) (1985) (0)
- The S-oxidation of methylthio-2,3',4',5-tetrachloro- biphenyl with rat liver microsomes (2000) (0)
- Fatty acid conjugates of 11-hydroxy-Δ8-tetrahydrocannabinol : In vitro formation and hydrolysis by the mouse pancreas (1996) (0)
- Extremely High Affinity of 2, 3, 4, 7, 8-Pentachlorodibenzofuran for Hepatic Microsomes of Rats (Regular Presentations) (Proceedings of the 10 th Symposium on Environmental Pollutants and Toxicology) (1984) (0)
- [Comparative study on metabolism of three tetrachlorobiphenyls with animal liver microsomes]. (1999) (0)
- Metabolism of drugs. I. The metabolic fate of ethylhexabital (5-cyclohexenyl-5-ethylbarbituric acid.) (1). (1954) (0)
- Effect of Coplanar PCB on Gluconeogenesis and Lipid Metabolism : Comparison between Rats and Guinea Pigs (Proceedings of the 19th Symposium on Toxicology and Environmental Health) (1994) (0)
- Metabolic conversion of delta 8 tetra hydro cannabinol to delta 8 tetra hydro cannabinol 11 oic acid and its pharmacological implications (1980) (0)
- IN VITRO METABOLIC FORMATION OF 8α, 9α-EPOXYHEXAHYDROCANNABINOL AND ITS IMPLICATION IN THE PHARMACOLOGICAL ACTIVITY OF Δ^8-TETRAHYDROCANNABINOL (1982) (0)
- PURIFICATION AND CHARACTERIZATION ON 3,4,5,3', 4'-PENTACHLOROBIPHENYL-INDUCIBLE CYTOCHROME P-450 IN CHICKEN LIVER (1987) (0)
- Metabolism of drugs. 63. The metabolic fate of 14C-phenacetylurea (phenurone) in mice. (1969) (0)
- CORRELATION BETWEEN A UNIQUE CHANGE OF STEROID METABOLISM AND CYTOCHROME P-450 INDUCED BY PRETREATMENT WITH 3-METHYLCHOLANTHRENE-TYPE PCB AND PCDF (1984) (0)
- Metabolic disposition of 8 alpha, 9 alpha- and 8 beta, 9 beta-epoxyhexahydrocannabinols in the mouse. (1984) (0)
- Studies on cis-trans isomerization of nitrofuran derivatives by bacterial nitroreductases. (1984) (0)
- Intracellular Distribution and Binding to Cytosolic Protein of 2, 3, 4, 7, 8-Pentachlorodibenzofuran in the Liver of Rats (Regular Presentations) (Proceedings of the 11 th Symposium on Environmental Pollutants and Toxicology) (1985) (0)
- MECHANISM OF SLEEP-PROLONGATING EFFECT OF Δ^8-TETRAHYDROCANNABINOL (Δ^8-THC) AND ITS METABOLITES (1981) (0)
- [Metabolism of drugs. LXXXIII. Metabolism of morphine glucuronides in rats (author's transl)]. (1975) (0)
- A Modification of the Methyl Orange Method for Estimation of Morphine (1968) (0)
- [Metabolism of drugs. LXXXIV. Metabolism of morphine glucuronides in rabbits, guinea pigs and mice (author's transl)]. (1975) (0)
- EFFECT OF COBALTOUS CHLORIDE-TREATMENT ON DRUG METABOLIZING ENZYMES AND TOXICITES INDUCED BY METHYLCHOLANTHRENE-TYPE PCB (1985) (0)
- Species difference of UDP-glucuronyltransferase isozymes in liver microsomes (1989) (0)
- Interaction of cannabinoids with hepatic microsomal drug-metabolizing enzyme system in the rat (1991) (0)
- Metabolic Activation and Detoxication of Polychlorinated Biphenyls (1987) (0)
- Metabolism of drugs. 78. The formation in vitro of oxoprolintane from prolintane by rabbit liver. (1972) (0)
- Stereospecific hydrolysis of 8 alpha,9 alpha- and 8 beta,9 beta-epoxyhexahydrocannabinols in the mouse in vivo and in vitro. (1985) (0)
- 120. OXIDATIVE ENZYME SYSTEM OF 11-HYDROXY Δ^8-THC (ACTIVE METABOLITE OF Δ^8-THC) IN HEPATIC MICROSOMES (The Third Meeting for the Study of Toxic Effect) (1977) (0)
- Effect of 3-Methylcholanthrene-and Phenobarbital-Type Polychlorinated Biphenyls (PCBs) on the Liver Soluble Enzymes of Rats (Regular Presentations) (Proceedings of the 9th Symposium on Environmental Pollutants and Toxicology) (1983) (0)
- Metabolism of Tetrachlorobiphenyls by Chinese Hamster Liver Microsomes (2007) (0)
- B-16 SUBSTRATE SPECIFICITY OF PURIFIED FAD-MONOOXYGENASE TOWARD MORPHINE AND COCAINE CONGENERS (1990) (0)
- [Hepatic accumulation of PCDF and its action on enzyme induction in PCB-intoxicated monkeys]. (1983) (0)
- [Metabolism of drugs. LIV. On the pharmacological action of carbamate N-glucuronides]. (1966) (0)
- [Effects of impurities on enzyme induction and toxicity in rats treated with 2,3,7,8-tetrachlorodibenzofuran]. (1985) (0)
- TOXICOLOGICAL ASSESSMENT OF POLYCHLORINATED DIBENZOFURANS (PCDF). I. RELATIONSHIP BETWEEN INDUCTIVE EFFECTS ON HEPATIC ENZYMES AND TOXICITIES OF PURE PCDF CONGENERS RETAINED IN YUSHO PATIENTS (1980) (0)
- Metabolism of drugs. LXXVII. In vitro metabolism of antipyrine. (1972) (0)
- METABOLIC ACTIVATION OF Δ^8-THTRAHYDROCANNABINOL (Δ^8-THC) AT THE 7-POSITION AND MECHANISM OF THE OXIDATION OF 7-HYDROXY-Δ^8-THC TO 7-OXO-Δ^8-THC WITH LIVER MICROSOMES (1985) (0)
- Microsomal oxygenase catalyzed oxidation of 11-hydroxy-delta 8-tetrahydrocannabinol to 11-oxo-delta 8-tetrahydrocannabinol. (1979) (0)
- Identification and determination of 8 alpha, 9 alpha-epoxyhexahydrocannabinol as a metabolite of delta 8-tetrahydrocannabinol of mice in vitro. (1982) (0)
- Liver Cytochrome P-450 Isozyme Responsible for the Metabolism of Tetrachlorobiphenyls in Rat (Proceedings of the 16 th Symposium on Environmental Pollutants and Toxicology) (1991) (0)
- Multiple udp-glucuronyltransferases from rat liver microsomes (1983) (0)
- [Studies on experimental PCB poisoning in crab-eating monkeys. III]. (1987) (0)
- METABOLIC FATE OF STRYCHNINE IN VITRO (1985) (0)
- Altered thiamine propyl disulfide metabolism in rats with liver injury induced by carbon tetrachloride and D-galactosamine. (1983) (0)
- COMPOSITION AND PROPERTIES OF SULFOXIDE-REDUCING ENZYME SYSTEMS (1981) (0)
- TOLERANCE DEVELOPMENT TO HYPOTHERMIC EFFECT OF Δ^8-TETRAHYDROCANNABINOL AND ITS ACTIVE METABOLITES (1982) (0)
- PURIFICATION AND CHARACTERIZATION OF MOUSE HEPATIC MICROSOMAL ALDEHYDE OXYGENASE (1990) (0)
- THE ENHANCING EFFECT ON THE PHARMACOLOGICAL ACTIVITY OF MORPHINE BY CONJUGATION AT THE 6-POSITION (1985) (0)
- SUPPRESSIVE MECHANISM OF INTERFERON INDUCER, POLYRIBOINOSINIC ACID-POLYRIBOCYTIDYLIC ACID, ON THE INDUCTION OF CYTOCHROME P-450 IN RAT LIVER MICROSOMES (1986) (0)
- Identification and determination of 11-oxo-delta8-tetrahydrocannabinol as an intermediate metabolite of delta8-tetrahydrocannabinol in the mouse brain and liver. (1980) (0)
- Mechanism of cannabielsoin formation from cannabidiol, one of the major CMPO-nents of marihuana (1990) (0)
- INHIBITORY EFFECT OF CANNABIDIOL ON THE HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEM IN THE RAT (1989) (0)
- STUDY ON MOUSE HEPATIC MICROSOMAL ALCOHOL OXYGENASE (MALCO) AND ITS REACTION MECHANISM (1997) (0)
- [Long-term effect of 3, 4, 5, 3', 4'-pentachlorobiphenyl on the toxicity and liver enzyme activities in rats]. (1987) (0)
- Metabolic activation of delta 8 tetrahydrocannabinol delta 8 at the 7 position and mechanism of the oxidation of 7 hydroxy delta 8 tetrahydrocannabinol to 7 oxo delta 8 tetrahydrocannabinol with liver microsomes (1985) (0)
- Inhibition of Cytochrome P-448H Dependent Catalytic Activity by 3, 4, 5, 3', 4'-Pentachlorobiphenyl (Regular Presentations) (Proceedings of the 15 th Symposium on Environmental Pollutants and Toxicology) (1990) (0)
- SYNTHESIS AND PHARMACOLOGICAL EFFECT OF MORPHINE PHOSPHATE ESTERS (1974) (0)
- A property of a novel esterase (ES46.5K) from mouse hepatic microsomes : Hydrolysis of acylated derivatives of 11-hydroxy-Δ8-tetrahydrocannabinol (1996) (0)
- [Hepatic enzyme induction by 3-methylcholanthrene-type PCB and development of its toxicity]. (1983) (0)
- Is serotonin involved in hypothermic effect and its tolerance development of Δ8-tetrahydrocannabinol and 11-hydroxy-Δ8-tetrahydrocannabinol in the mouse? (1984) (0)
- Multiple UDP-glucuronyl transferases from rat liver microsomes. (1983) (0)
- Cellular Uptake of 2,3,4,7,8-Pentachlorodibenzofuran in the Rat Liver (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations) (1986) (0)
- [The metabolism of drugs. LXXXV. The metabolism of 1-p-chlorophenyl-2,3-dimethyl-4-dimethylaminobutan-2-ol hydrochloride (author's transl)]. (1975) (0)
- Pharmacological activities in mice of a nitrogen-containing cannabinoid, 3-pentyl-4-amino-6,6,9-trimethyl-(2-methyloxazolo)-[5,4-a]-6H-dibenzopyrane (1992) (0)
- Enhancement of Reduction Activity of 4NQO in Animals pretreated with 3-Methylcholanthrene-type PCB and PCDF (Regular Presentations) (Proceedings of the 8th Symposium on Environmental Pollutants and Toxicology) (1982) (0)
- Induction of a High-Spin Form of Cytochrome P-450 by Highly Toxic Polychlorinated Aromatic Hydrocarbons (Proceedings of the 14th Symposium on Environmental Pollutants and Toxicology) (1989) (0)
- Induction of Bilirubin UDP-Glucuronyltransferase and P-450 4A Subfamily in Guinea Pigs by Treatment with Coplanar PCB (Proceedings of the 18th Symposium on Toxicology, and Environmental Health) (1993) (0)
- MECHANISM OF THE PROLONGATION OF BARBITURATE-INDUCED SLEEPING TIME AND THE INHIBITION OF THE HEPATIC MICROSOMAL DRUG METABOLIZING ENZYMES BY CANNABIDIOL, A COMPONENT OF CANNABIS (1986) (0)
- Tolerance development to catalepsy, hypothermia and pentobarbital -induced sleep prolonging effect of 8α,9β- and 8β,90β-apoxyhexahydrocannabinols (EHHCs) in mice (1983) (0)
- NOVEL COLUMN CHROMATOGRAPHY PROCEDURE FOR THE PURIFICATION OF UDP-GLUCURONYLTRANSFERASES (1992) (0)
- Inhibitory effects of tetrahydrocannabinols and their ten oxygenated metabolites on adenosine triphosphatase activity (1988) (0)
- Synthesis of Potassium Benzo (α) pyren-3-yl Sulfate (1980) (0)
- CYTOCHROME P450 INVOLVING IN THE METABOLIC ACTIVATION OFCANNABINOIDS (1995) (0)
- PURIFICATION AND CHARACTERIZATION OF MICROSOMAL ALCOHOL OXYGENASE (MALCO) THAT CATALYZES THE FORMATION OF 7-OXO-Δ8 TETRAHYDROCANNABINOL FROM 7-HYDROXY-Δ8-TETRAHYDROCANNABINOL (1994) (0)
- THE OCCURRENCE OF (OMEGA-1)-HYDROXYLATION AS THE MAJOR METABOLISM OF ALKYLARYL ETHERS IN RABBITS. (1964) (0)
- Mechanisms of Stimulated Fecal Excretion of Polychlorinated Aromatic Hydrocarbons in Rats (1987) (0)
- [Relationship between tissue distribution and acute toxicity of 2, 3, 4, 7, 8-pentachlorodibenzofuran in rats given sub-lethal doses]. (1987) (0)
- STUDIES ON THE MECHANISM OF N-DEMETHYLATION OF METHAMPHETAMINE WITH PURIFIED ENZYMES (1987) (0)
- STUDIES ON ENZYMIC REDUCTION OF NITRO COMPOUNDS (1981) (0)
- Purification and Characterization of a Novel Esterase That Hydrolyzes Cannabinoid-11-hydroxyesters from Mouse Hepatic Microsomes (1993) (0)
- IN VIVO METABOLITES OF 3,4,3', 4', -TETRACHLOROBIPHENYL AND THE TOXICOLOGICAL ASSESSMENT IN RATS (1986) (0)
- HEPATIC MICROSOMAL OXYGENATION OF METHYL GROUP TO CARBOXYLIC ACID IN XENOBIOTICS : METABOLISM OF Δ^8-TETRAHYDROCANNABINOL AT THE 11-POSITION (1989) (0)
- STUDIES ON THE METABOLISM OF NITROFURAN DERIVATIVES IN BACTERIA : PROPERTIES OF CIS-TRANS ISOMERASES AND NITROREDUCTASES, AND RELATIONSHIP OF THESE ENZYMES (1980) (0)
- Polychlorinated biphenyls and dibenzofurans in patients with yusho and their toxicological significance: a review. (1984) (0)
- IN VITRO METABOLISM OF TETRAHYDROCANNABINOL (THC) BY HUMAN LIVER MICROSOMES. EPOXIDE-DIOL PATHWAY OF THC (1984) (0)
- Cross-tolerance to the hypothermic effect of delta 8-tetrahydrocannabinol 11-hydroxy-delta 8-tetrahydrocannabinol and chlorpromazine in the mouse. (1985) (0)
- METABOLISM OF DRUGS. 48. THE STUDY OF SELECTIVE DEMETHYLATION OF BRUCINE IN VIVO. (1964) (0)
- 8 alpha, 9 alpha-Epoxyhexahydrocannabinol formation from delta 8-tetrahydrocannabinol by mouse liver microsomes. (1982) (0)
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