Hana El-Samad
#125,429
Most Influential Person Now
Lebanese-American Biological scientist
Hana El-Samad's AcademicInfluence.com Rankings
Hana El-Samadengineering Degrees
Engineering
#7814
World Rank
#9245
Historical Rank
Bioengineering
#121
World Rank
#123
Historical Rank
Hana El-Samadphysics Degrees
Physics
#9007
World Rank
#11350
Historical Rank
Biophysics
#420
World Rank
#432
Historical Rank
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Engineering Physics
Hana El-Samad's Degrees
- PhD Biophysics University of California, San Francisco
- Bachelors Bioengineering University of California, Berkeley
Why Is Hana El-Samad Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hana El-Samad is a Lebanese-American scientist who is a founding Principal Investigator at Altos Labs and a Professor of Biochemistry and Biophysics at the University of California, San Francisco. Her work considers control theory and the function of complex biological systems. Her group has made contributions to systems biology, synthetic biology, and cell engineering.
Hana El-Samad's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Defining Network Topologies that Can Achieve Biochemical Adaptation (2009) (835)
- Conformational biosensors reveal GPCR signalling from endosomes (2013) (692)
- BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response (2010) (365)
- In silico feedback for in vivo regulation of a gene expression circuit (2011) (280)
- Surviving heat shock: control strategies for robustness and performance. (2005) (279)
- Calcium homeostasis and parturient hypocalcemia: an integral feedback perspective. (2002) (190)
- De Novo Design of Bioactive Protein Switches (2019) (155)
- Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae. (2012) (150)
- Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity (2011) (145)
- Low Dimensionality in Gene Expression Data Enables the Accurate Extraction of Transcriptional Programs from Shallow Sequencing. (2016) (120)
- De novo design of protein logic gates (2020) (111)
- Bound attractant at the leading vs. the trailing edge determines chemotactic prowess (2007) (107)
- Module-Based Analysis of Robustness Tradeoffs in the Heat Shock Response System (2006) (104)
- Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs (2018) (103)
- Population Diversification in a Yeast Metabolic Program Promotes Anticipation of Environmental Shifts (2014) (94)
- Modular and tunable biological feedback control using a de novo protein switch (2019) (79)
- Advanced Methods and Algorithms for Biological Networks Analysis (2006) (75)
- Regulated degradation is a mechanism for suppressing stochastic fluctuations in gene regulatory networks. (2006) (68)
- Synergistic dual positive feedback loops established by molecular sequestration generate robust bimodal response (2012) (66)
- Coordinate control of gene expression noise and interchromosomal interactions in a MAPK pathway (2010) (62)
- Discriminating between rival biochemical network models: three approaches to optimal experiment design (2010) (60)
- Robust Synthetic Circuits for Two-Dimensional Control of Gene Expression in Yeast. (2017) (57)
- Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions. (2010) (57)
- Repressilators and promotilators: loop dynamics in synthetic gene networks (2005) (56)
- Feedback regulation of the heat shock response in E. coli (2001) (56)
- Tuning the Activation Threshold of a Kinase Network by Nested Feedback Loops (2009) (54)
- Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses (2012) (53)
- Msn2 Coordinates a Stoichiometric Gene Expression Program (2013) (48)
- Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals “aging factors” and mechanism of lifespan asymmetry (2015) (47)
- Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control (2018) (45)
- Dynamic Characterization of Growth and Gene Expression Using High-throughput Automated Flow cytometry (2014) (42)
- Reversible-equivalent-monomolecular tau: A leaping method for "small number and stiff" stochastic chemical systems (2007) (42)
- Systems biology: from physiology to gene regulation (2004) (40)
- Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression (2016) (40)
- Delayed Ras/PKA signaling augments the unfolded protein response (2014) (40)
- Model validation and robust stability analysis of the bacterial heat shock response using SOSTOOLS (2003) (34)
- Optogenetic Control Reveals Differential Promoter Interpretation of Transcription Factor Nuclear Translocation Dynamics (2019) (33)
- Design and analysis of a Proportional-Integral-Derivative controller with biological molecules (2018) (33)
- Building robust functionality in synthetic circuits using engineered feedback regulation. (2013) (31)
- Design and Analysis of a Proportional-Integral-Derivative Controller with Biological Molecules. (2019) (28)
- Not all quiet on the noise front. (2009) (22)
- A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells. (2019) (22)
- A rigorous framework for multiscale simulation of stochastic cellular networks. (2009) (20)
- Robustness analysis of the heat shock response in E. coli (2002) (19)
- Biological feedback control-Respect the loops. (2021) (18)
- Stochastic stability and its application to the analysis of gene regulatory networks (2004) (18)
- A Toolkit for Rapid Modular Construction of Biological Circuits in Mammalian Cells (2018) (18)
- Model-guided optogenetic study of PKA signaling in budding yeast (2017) (17)
- Multicellular Architecture of Malignant Breast Epithelia Influences Mechanics (2014) (15)
- Using Dynamic Noise Propagation to Infer Causal Regulatory Relationships in Biochemical Networks (2014) (15)
- Algorithms for Discriminating Between Biochemical Reaction Network Models: Towards Systematic Experimental Design (2007) (14)
- Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics (2016) (12)
- Stochastic modeling of cellular networks. (2012) (11)
- Multidimensional Characterization of Parts Enhances Modeling Accuracy in Genetic Circuits. (2020) (11)
- Control theoretical concepts for synthetic and systems biology (2019) (11)
- Synthetic cytokine circuits that drive T cell infiltration into immune-excluded tumors (2022) (10)
- Stochastic Modeling and Analysis of Genetic Networks (2005) (10)
- Modelling and analysis of gene regulatory network using feedback control theory (2010) (9)
- The Impact of Different Sources of Fluctuations on Mutual Information in Biochemical Networks (2015) (9)
- Stochastic reachability analysis in complex biological networks (2006) (9)
- Stress-induced growth rate reduction restricts metabolic resource utilization to modulate osmo-adaptation time. (2021) (8)
- A data-integrated method for analyzing stochastic biochemical networks. (2011) (8)
- Coherence Resonance: A Mechanism for Noise Induced Stable Oscillations in Gene Regulatory Networks (2006) (8)
- Multi-kinase control of environmental stress responsive transcription (2020) (8)
- Orthogonal control of mean and variability of endogenous genes in a human cell line (2021) (7)
- A master equation and moment approach for biochemical systems with creation-time-dependent bimolecular rate functions. (2014) (7)
- Genetics: Noise rules (2011) (6)
- A population shift between two heritable cell types of the pathogen Candida albicans is based both on switching and selective proliferation (2019) (6)
- Calcium homeostasis: a feedback control point of view (2000) (5)
- Can a systems perspective help us appreciate the biological meaning of small effects? (2011) (5)
- Towards a minimal stochastic model for a large class of diffusion-reactions on biological membranes. (2012) (5)
- Sentinel cells enable genetic detection of SARS-CoV-2 Spike protein (2021) (4)
- De novo design of tyrosine and serine kinase-driven protein switches (2021) (4)
- Control Strategies in Times of Adversity: How Organisms Survive Stressful Conditions (2009) (4)
- Intrinsic noise rejection in gene networks by regulation of stability (2004) (4)
- Stress-Induced Transient Cell Cycle Arrest Coordinates Metabolic Resource Allocation to Balance Adaptive Tradeoffs (2020) (3)
- Tradeoffs in adapting biological systems (2016) (3)
- Real time genetic compensation operationally defines the dynamic demands of feedback control (2018) (3)
- Assembly of Genetic Circuits with the Mammalian ToolKit. (2020) (3)
- What Have the Principles of Engineering Taught Us about Biological Systems? (2016) (3)
- Formation of subnuclear foci is a unique spatial behavior of mating MAPKs during hyperosmotic stress. (2013) (3)
- Accurate prediction of genetic circuit behavior requires multidimensional characterization of parts (2020) (2)
- Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs (2019) (2)
- Biphasic Response of Protein Kinase A to Cyclic Adenosine Monophosphate Triggers Distinct Epithelial Phenotypes (2019) (2)
- Competitive Displacement of De Novo Designed HeteroDimers Can Reversibly Control Protein–Protein Interactions and Implement Feedback in Synthetic Circuits (2022) (2)
- A dataset to explore kinase control of environmental stress responsive transcription (2019) (1)
- From Physiology to Gene Regulation (2004) (1)
- Synthetic transcriptional synergy (2019) (1)
- Author response: Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression (2016) (1)
- Optogenetic control of RelA reveals effect of transcription factor dynamics on downstream gene expression (2022) (1)
- Publisher Correction: Modular and tunable biological feedback control using a de novo protein switch (2020) (1)
- CoRa—A general approach for quantifying biological feedback control (2020) (1)
- Paralogs in the PKA regulon traveled different evolutionary routes to divergent expression in budding yeast (2019) (1)
- Complexity-aware simple modeling. (2018) (1)
- GEN Biotechnology and the New Age of Bioinnovation (2022) (0)
- Feedback analysis of calcium homeostasis and parturient paresis (2000) (0)
- Modeling and simulation of cellular functions (2012) (0)
- The Vision for GEN Biotechnology: From Precision Biology to Engaging a Broad Audience (2022) (0)
- Article Msn2 Coordinates a Stoichiometric Gene Expression Program (2013) (0)
- TuNR: Orthogonal Control of Mean and Variability of Endogenous Genes in a Human Cell Line (2020) (0)
- silencing factors in the elimination of nucleosome-free regions Combinatorial , site-specific requirement for heterochromatic Material Supplemental (2010) (0)
- Publisher Correction: Modular and tunable biological feedback control using a de novo protein switch (2020) (0)
- Orthogonal control of mean and variability of endogenous genes in a human cell line (2021) (0)
- Homeostatic Regulation of the Unfolded Protein Response (2011) (0)
- Unraveling Biological Design Principles Using Engineering Methods: The Heat Shock Response as a Case Study (2006) (0)
- Complexity-Aware Simple Modeling (2018) (0)
- A non-memoryless stochastic simulation algorithm for modeling diffusion-reactions on biological membranes (2012) (0)
- Low Dimensionality in Gen e Expression Data Enables the Accurate Extraction of Transcriptional Programs from Shallow Sequencing Graphical (2016) (0)
- Title Controlling CRISPR-Cas 9 with ligand-activated and ligand-deactivated sgRNAs (2019) (0)
- Title Homeostatic adaptation to endoplasmic reticulum stress depends on Ire 1 kinase activity (2011) (0)
- Formation of Sub-Nuclear Foci is a Novel Spatial Behavior of Mating MAPKs during Hyper-Osmotic Stress (2013) (0)
- Noise in Gene Expression Reveals Cellular Pathways (2005) (0)
- Sensitivity Analysis and Model Reduction Applied to Adapting Biological Systems (2014) (0)
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What Schools Are Affiliated With Hana El-Samad?
Hana El-Samad is affiliated with the following schools:
