Hanah Margalit
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Principal Investigator in the Faculty of Medicine The Hebrew University of Jerusalem
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Why Is Hanah Margalit Influential?
(Suggest an Edit or Addition)According to Wikipedia, Hanah Margalit is a Professor in the faculty of medicine at the Hebrew University of Jerusalem. Her research combines bioinformatics, computational biology and systems biology, specifically in the fields of gene regulation in bacteria and eukaryotes.
Hanah Margalit's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- IntAct: an open source molecular interaction database (2004) (967)
- Clustering and conservation patterns of human microRNAs (2005) (803)
- Novel small RNA-encoding genes in the intergenic regions of Escherichia coli (2001) (785)
- Host Immune System Gene Targeting by a Viral miRNA (2007) (695)
- Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins. (1987) (605)
- Network motifs in integrated cellular networks of transcription-regulation and protein-protein interaction. (2004) (554)
- Prediction of immunodominant helper T cell antigenic sites from the primary sequence. (1987) (466)
- Comparative Functional Genomics of the Fission Yeasts (2011) (439)
- How reliable are experimental protein-protein interaction data? (2003) (439)
- Correlated sequence-signatures as markers of protein-protein interaction. (2001) (423)
- Compilation of E. coli mRNA promoter sequences. (1993) (364)
- Regulation of gene expression by small non-coding RNAs: a quantitative view (2007) (304)
- Global Mapping of Small RNA-Target Interactions in Bacteria (2016) (267)
- Construction of synthetic immunogen: use of new T-helper epitope on malaria circumsporozoite protein. (1987) (260)
- A survey of small RNA-encoding genes in Escherichia coli. (2003) (255)
- Molecular Basis for Expression of Common and Rare Fragile Sites (2003) (238)
- Comparative analysis of structurally defined heparin binding sequences reveals a distinct spatial distribution of basic residues. (1993) (226)
- Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. (1998) (225)
- Small RNAs encoded within genetic islands of Salmonella typhimurium show host-induced expression and role in virulence (2008) (217)
- Comprehensive analysis of hydrogen bonds in regulatory protein DNA-complexes: in search of common principles. (1995) (204)
- Patched 1 Regulates Hedgehog Signaling at the Primary Cilium (2007) (193)
- Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native protein using a 16-residue synthetic peptide. (1987) (160)
- Microsatellite spreading in the human genome: evolutionary mechanisms and structural implications. (1996) (157)
- A role for CH...O interactions in protein-DNA recognition. (1998) (156)
- Structure‐based prediction of binding peptides to MHC class I molecules: Application to a broad range of MHC alleles (2000) (156)
- Quantitative parameters for amino acid-base interaction: implications for prediction of protein-DNA binding sites. (1998) (151)
- Hierarchy of sequence-dependent features associated with prokaryotic translation. (2003) (149)
- Protein Antigenic Structures Recognized by T Cells; Potential Applications to Vaccine Design (1987) (132)
- Integration of Bacterial Small RNAs in Regulatory Networks. (2017) (130)
- Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge (2005) (124)
- Strong conformational propensities enhance T cell antigenicity. (1987) (114)
- Ranking potential binding peptides to MHC molecules by a computational threading approach. (1995) (108)
- Identification of an immunodominant and highly immunopathogenic determinant in the retinal interphotoreceptor retinoid-binding protein (IRBP) (1989) (107)
- Evolutionary conservation of domain-domain interactions (2006) (101)
- Built-in loops allow versatility in domain–domain interactions: Lessons from self-interacting domains (2008) (95)
- Variation in global codon usage bias among prokaryotic organisms is associated with their lifestyles (2011) (94)
- Legionella pneumophila 6S RNA optimizes intracellular multiplication (2010) (89)
- Identification and characterization of E.coli ribosomal binding sites by free energy computation. (1993) (88)
- Accessibility and Evolutionary Conservation Mark Bacterial Small-RNA Target-Binding Regions (2011) (83)
- Conserved sequence elements associated with exon skipping. (2003) (82)
- Chromosomal organization is shaped by the transcription regulatory network. (2005) (80)
- T cell multideterminant regions in the human immunodeficiency virus envelope: toward overcoming the problem of major histocompatibility complex restriction. (1989) (78)
- A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets. (1997) (78)
- Characterization and prediction of protein–protein interactions within and between complexes (2006) (72)
- PromEC: An updated database of Escherichia coli mRNA promoters with experimentally identified transcriptional start sites (2001) (70)
- Towards an Integrated Protein-Protein Interaction Network: A Relational Markov Network Approach (2006) (69)
- A structure-based approach for prediction of MHC-binding peptides. (2004) (68)
- Relative predicted protein levels of functionally associated proteins are conserved across organisms (2005) (67)
- Cytomegalovirus microRNAs Facilitate Persistent Virus Infection in Salivary Glands (2010) (67)
- Persistently conserved positions in structurally similar, sequence dissimilar proteins: Roles in preserving protein fold and function (2002) (58)
- Sequence signals for generation of antigenic peptides by the proteasome: implications for proteasomal cleavage mechanism. (2000) (58)
- A Dynamic View of Domain-Motif Interactions (2012) (57)
- RepTar: a database of predicted cellular targets of host and viral miRNAs (2010) (56)
- A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval (2008) (54)
- Evolutionary patterns of Escherichia coli small RNAs and their regulatory interactions (2014) (53)
- Knowledge-based structure prediction of MHC class I bound peptides: a study of 23 complexes. (1998) (51)
- Stochastic Analysis of the SOS Response in Escherichia coli (2009) (49)
- A functional selection model explains evolutionary robustness despite plasticity in regulatory networks (2012) (48)
- Post-transcriptional 3´-UTR cleavage of mRNA transcripts generates thousands of stable uncapped autonomous RNA fragments (2017) (46)
- Evaluation of PSI‐BLAST alignment accuracy in comparison to structural alignments (2000) (44)
- Competition between small RNAs: a quantitative view. (2012) (44)
- Interactions between Distant ceRNAs in Regulatory Networks (2014) (43)
- Identification of common motifs in unaligned DNA sequences: application to Escherichia coli Lrp regulon (1995) (43)
- Mapping the small RNA interactome in bacteria using RIL-seq (2017) (42)
- Molecular analysis of HLA class II genes in primary Sjögren's syndrome. A study of Israeli Jewish and Greek non-Jewish patients. (1993) (42)
- Synthetic peptides derived from IRBP induce EAU and EAP in Lewis rats. (1988) (42)
- Assessing the functional association of intronic miRNAs with their host genes (2018) (41)
- Co-evolution of transcription factors and their targets depends on mode of regulation (2006) (41)
- Sequence features that correlate with MHC restriction. (1994) (39)
- Structure and function of the Pseudomonas putida integration host factor (1996) (38)
- A Structure-Based Approach for Prediction of Protein Binding Sites in Gene-Upstream Regions (2000) (37)
- Detection of regulatory circuits by integrating the cellular networks of protein-protein interactions and transcription regulation. (2003) (37)
- Conservation of salt bridges in protein families. (1995) (36)
- A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs. (2012) (36)
- A Ubiquitous Platform for Bacterial Nanotube Biogenesis (2019) (36)
- Determination of common structural features in Escherichia coli promoters by computer analysis. (1994) (34)
- Modularity and directionality in genetic interaction maps (2010) (33)
- Helix stability in prokaryotic promoter regions. (1988) (32)
- Detection of common motifs in RNA secondary structures. (1989) (32)
- A wide repertoire of miRNA binding sites: prediction and functional implications (2011) (31)
- Assigning functions to genes: identification of S-phase expressed genes in Leishmania major based on post-transcriptional control elements (2005) (31)
- Common fragile sites: G-band characteristics within an R-band. (1999) (30)
- Codon usage bias in prokaryotic pyrimidine-ending codons is associated with the degeneracy of the encoded amino acids (2012) (30)
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. (1993) (29)
- Proteins of the same fold and unrelated sequences have similar amino acid composition (2006) (25)
- Identification of T-cell epitopes and use in construction of synthetic vaccines. (1989) (24)
- Markovian domain fingerprinting: statistical segmentation of protein sequences (2001) (23)
- Nucleotide sequence, organization and characterization of the atp genes and the encoded subunits of Mycoplasma gallisepticum ATPase. (1992) (22)
- Repeated determinants within the retinal interphotoreceptor retinoid-binding protein (IRBP): immunological properties of the repeats of an immunodominant determinant. (1990) (21)
- Common Adaptive Strategies Underlie Within-Host Evolution of Bacterial Pathogens (2020) (20)
- Hierarchy in Hfq Chaperon Occupancy of Small RNA Targets Plays a Major Role in Their Regulation (2020) (20)
- A defense-offense multi-layered regulatory switch in a pathogenic bacterium (2015) (20)
- Immune responses to peptides derived from the retinal protein IRBP: immunopathogenic determinants are not necessarily immunodominant. (1989) (18)
- In vivo cleavage rules and target repertoire of RNase III in Escherichia coli (2018) (17)
- Periodic variation in side-chain polarities of T-cell antigenic peptides correlates with their structure and activity. (1995) (17)
- Global RNA interactome of Salmonella discovers a 5′ UTR sponge for the MicF small RNA that connects membrane permeability to transport capacity (2022) (16)
- A complete Alu element within the coding sequence of a central gene (1994) (16)
- In vivo cleavage rules and target repertoire of RNase III in Escherichia coli (2018) (15)
- Towards an Integrated Protein-Protein Interaction Network (2005) (14)
- Initiation of DNA replication in bacteria: analysis of an autorepressor control model. (1984) (14)
- In vivo mapping of RNA-RNA interactions in Staphylococcus aureus using the endoribonuclease III. (2013) (14)
- Auxiliary tRNAs: large-scale analysis of tRNA genes reveals patterns of tRNA repertoire dynamics (2014) (13)
- Molecular features of class II MHC-restricted T-cell recognition of protein and peptide antigens: the importance of amphipathic structures. (1986) (13)
- Preferential use of protein domain pairs as interaction mediators: order and transitivity (2010) (12)
- Degradation of Ndd1 by APC/CCdh1 generates a feed forward loop that times mitotic protein accumulation (2015) (11)
- Prediction of Novel Bacterial Small RNAs From RIL-Seq RNA–RNA Interaction Data (2021) (10)
- The impact of Hfq-mediated sRNA-mRNA interactome on the virulence of enteropathogenic Escherichia coli (2021) (9)
- Initiation of chromosome replication in bacteria: analysis of an inhibitor control model (1987) (8)
- Molecular structure and vaccine design. (1990) (8)
- Examination of possible structural constraints of MHC‐binding peptides by assessment of their native structure within their source proteins (2001) (8)
- Stochastic analysis of bistability in coherent mixed feedback loops combining transcriptional and posttranscriptional regulations. (2014) (8)
- Correction: A Dynamic View of Domain-Motif Interactions (2012) (7)
- Glimmers in the Midnight Zone: Characterization of Aligned Identical Residues in Sequence-Dissimilar Proteins Sharing a Common Fold (2000) (6)
- Insights from MHC-bound peptides. (2003) (6)
- Global regulation of transcription by a small RNA: a quantitative view. (2014) (5)
- Immunodominance of Amphipathic Peptides and Their Localization on the Cell Surface for Antigen Presentation to Helper T Cells (1986) (5)
- Predicting Transcription Factor Binding Sites Using Structural Knowledge (2005) (5)
- REGULATION OF GENE EXPRESSION BY SMALL NON-CODING RNAS (2007) (3)
- Reduced Polymorphism in Domains Involved in Protein-Protein Interactions (2012) (3)
- PeCoP: automatic determination of persistently conserved positions in protein families (2002) (3)
- Harnessing the cellular immune system to the gene-prediction cart. (2001) (2)
- Approaches and developments in studying the human microbiome network (2015) (1)
- Molecular analysis of HLA class II genes in primary sjo¨gren's syndrome (1993) (0)
- 10 – The Role of MHC and Amphipathic Structures in T Cell Recognition: Features Determining Immunodominance (1988) (0)
- Post-transcriptional 3´-UTR cleavage of mRNA transcripts generates thousands of stable uncapped autonomous RNA fragments (2017) (0)
- Convergent Within-Host Adaptation of Pseudomonas aeruginosa through the Transcriptional Regulatory Network (2023) (0)
- SURVEY A survey of small RNA-encoding genes in Escherichia coli (0)
- Synthetic peptides, cellular immunity against the AIDS virus and proteins produce a result. (1987) (0)
- Conservation patterns of known and predicted human miRNAs (2011) (0)
- Correction: A Novel Bayesian DNA Motif Comparison Method for Clustering and Retrieval (2011) (0)
- Inferring the contribution of small RNAs to changes in gene expression in response to stress (2022) (0)
- Artificial vaccine against the aids virus (1989) (0)
- Supporting Online Material for Comparative Functional Genomics of the Fission Yeasts (2011) (0)
- Helper t cell immunity implications for vaccines (1987) (0)
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What Schools Are Affiliated With Hanah Margalit?
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