Hasse Eklund

Hasse Eklund's AcademicInfluence.com Rankings

Hasse Eklund

Chemistry

#4500

World Rank

#5583

Historical Rank

Organic Chemistry

#747

World Rank

#844

Historical Rank

chemistry Degrees

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Chemistry

Hasse Eklund's Degrees

Bachelors Chemistry Stockholm University
PhD Chemistry Stockholm University

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Hasse Eklund's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Three-dimensional structure of the free radical protein of ribonucleotide reductase (1990) (657)
Three-dimensional structure of horse liver alcohol dehydrogenase at 2-4 A resolution. (1976) (590)
3 Alcohol Dehydrogenases (1975) (583)
Crystal structure of thioredoxin from Escherichia coli at 1.68 A resolution. (1990) (509)
Structure of ribonucleotide reductase protein R1 (1994) (476)
Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase. (1998) (459)
Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution. (1975) (377)
Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron (2003) (374)
Structure and function of the Escherichia coli ribonucleotide reductase protein R2. (1993) (342)
Structural and functional relations among thioredoxins of different species (1991) (342)
Structure of a triclinic ternary complex of horse liver alcohol dehydrogenase at 2.9 A resolution. (1981) (318)
Structure and function of the radical enzyme ribonucleotide reductase. (2001) (294)
Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. (1997) (218)
Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase. (1984) (204)
Binding of substrate in a ternary complex of horse liver alcohol dehydrogenase. (1982) (195)
Redox signaling in chloroplasts: cleavage of disulfides by an iron-sulfur cluster. (2000) (180)
Conformational and functional similarities between glutaredoxin and thioredoxins. (1984) (179)
Di-iron-carboxylate proteins. (1995) (173)
Medium- and short-chain dehydrogenase/reductase gene and protein families (2008) (167)
Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site. (1996) (166)
The structure of horse liver alcohol dehydrogenase (1974) (155)
Substrate binding site of naphthalene 1,2-dioxygenase: functional implications of indole binding. (2000) (144)
X-ray studies of the binding of Cibacron blue F3GA to liver alcohol dehydrogenase. (1979) (141)
Structure of Liver Alcohol Dehydrogenase at 2.9-Å Resolution (1973) (139)
Interdomain motion in liver alcohol dehydrogenase. Structural and energetic analysis of the hinge bending mode. (1979) (139)
Structural basis for substrate specificities of cellular deoxyribonucleoside kinases (2001) (139)
Micro diffusion cells for the growth of single protein crystals by means of equilibrium dialysis. (1968) (133)
Structure of betaine aldehyde dehydrogenase at 2.1 Å resolution (1998) (133)
Crystal structure of plant pectin methylesterase (2002) (129)
Structural snapshots along the reaction pathway of ferredoxin–thioredoxin reductase (2007) (128)
The three-dimensional structure of flavodoxin reductase from Escherichia coli at 1.7 A resolution. (1997) (123)
Structures of thymidine kinase 1 of human and mycoplasmic origin (2004) (123)
Molecular aspects of functional differences between alcohol and sorbitol dehydrogenases. (1985) (122)
Structures of Horse Liver Alcohol Dehydrogenase Complexed with NAD+ and Substituted Benzyl Alcohols (1994) (119)
The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2. (1996) (109)
Comparison of three classes of human liver alcohol dehydrogenase. Emphasis on different substrate binding pockets. (1990) (106)
Structural insight into the dioxygenation of nitroarene compounds: the crystal structure of nitrobenzene dioxygenase. (2005) (106)
Subunit conformation of yeast alcohol dehydrogenase. (1978) (105)
Crystal structure of Arabidopsis thaliana NADPH dependent thioredoxin reductase at 2.5 A resolution. (1996) (104)
Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases. (2002) (98)
Structural basis for light activation of a chloroplast enzyme: the structure of sorghum NADP-malate dehydrogenase in its oxidized form. (1999) (97)
Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme. (2004) (97)
Structural and evolutionary aspects of thioredoxin reductases in photosynthetic organisms. (2009) (95)
Substitution of manganese for iron in ribonucleotide reductase from Escherichia coli. Spectroscopic and crystallographic characterization. (1994) (87)
Crystal structure of NAD(P)H:flavin oxidoreductase from Escherichia coli. (1999) (83)
Structure of Salmonella typhimurium nrdF ribonucleotide reductase in its oxidized and reduced forms. (1998) (80)
Crystal structure determinations of coenzyme analogue and substrate complexes of liver alcohol dehydrogenase: binding of 1,4,5,6-tetrahydronicotinamide adenine dinucleotide and trans-4-(N,N-dimethylamino)cinnamaldehyde to the enzyme. (1982) (79)
The redox centers of ribonucleotide reductase of Escherichia coli. (1992) (75)
Pyrazole binding in crystalline binary and ternary complexes with liver alcohol dehydrogenase. (1982) (73)
Structural comparisons of mammalian, yeast and bacillar alcohol dehydrogenases. (1976) (69)
Structure of oxidized bacteriophage T4 glutaredoxin (thioredoxin). Refinement of native and mutant proteins. (1992) (69)
A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines (2002) (69)
Computer‐graphics interpretations of residue exchanges between the α, β and γ subunits of human‐liver alcohol dehydrogenase class I isozymes (1987) (67)
Glycyl radical enzymes: a conservative structural basis for radicals. (1999) (66)
Crystallography of liver alcohol dehydrogenase complexed with substrates. (1978) (65)
The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2. (1998) (61)
Crystal structure of thioredoxin-2 from Anabaena. (1995) (61)
Structural differences between apo- and holoenzyme of horse liver alcohol dehydrogenase. (1979) (58)
Correlation of exons with structural domains in alcohol dehydrogenase. (1984) (58)
Structural Basis of Redox Signaling in Photosynthesis: Structure and Function of Ferredoxin:thioredoxin Reductase and Target Enzymes (2004) (54)
Unusual clustering of carboxyl side chains in the core of iron-free ribonucleotide reductase (1993) (52)
The active site structure of methane monooxygenase is closely related to the binuclear iron center of ribonucleotide reductase (1992) (52)
A putative glutathione-binding site in T4 glutaredoxin investigated by site-directed mutagenesis. (1991) (51)
The major piscine liver alcohol dehydrogenase has class-mixed properties in relation to mammalian alcohol dehydrogenases of classes I and III. (1992) (50)
Crystal structure of cod liver class I alcohol dehydrogenase: Substrate pocket and structurally variable segments (1996) (49)
Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors. (2003) (49)
Binding of salicylate in the adenosine-binding pocket of dehydrogenases. (1974) (49)
X-ray crystal structure of benzoate 1,2-dioxygenase reductase from Acinetobacter sp. strain ADP1. (2002) (48)
How does light regulate chloroplast enzymes? Structure–function studies of the ferredoxin/thioredoxin system (2000) (48)
Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system (2008) (47)
Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyribonucleoside kinase. (2003) (44)
Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols. (1994) (39)
A single‐residue exchange gives human recombinant ββ alcohol dehydrogenase γγ isozyme properties (1992) (39)
Tetrameric NAD-dependent alcohol dehydrogenase. (2003) (38)
Crystal structure of sorbitol dehydrogenase. (2001) (37)
Modifications of the active center of T4 thioredoxin by site-directed mutagenesis. (1990) (33)
Cofactor mobility determines reaction outcome in the IMPDH/GMPR (β/α)8 barrel enzymes (2011) (33)
The Ten-stranded β/α Barrel in Ribonucleotide Reductase Protein R1 (1996) (33)
Crystallization and preliminary crystallographic studies of Saccharomyces cerevisiae alcohol dehydrogenase I. (1994) (30)
The reduction of the Rieske iron-sulfur cluster in naphthalene dioxygenase by X-rays. (2000) (29)
Crystal structures of the active site in specifically metal-depleted and cobalt-substituted horse liver alcohol dehydrogenase derivatives. (1983) (28)
Three-dimensional structure of isonicotinimidylated liver alcohol dehydrogenase. (1984) (26)
Structure of thioredoxin from Trypanosoma brucei brucei (2003) (26)
Enzyme and isozyme developments within the medium-chain alcohol dehydrogenase family. (1993) (24)
Ribonucleotide reductase--structural studies of a radical enzyme. (1997) (23)
Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme. (2005) (22)
Crystal structure analysis of a mutant Escherichia coli thioredoxin in which lysine 36 is replaced by glutamic acid. (1993) (21)
Active site specific cadmium(II)-substituted horse liver alcohol dehydrogenase: crystal structures of the free enzyme, its binary complex with NADH, and the ternary complex with NADH and bound p-bromobenzyl alcohol. (1985) (21)
Structure and mechanism of liver alcohol dehydrogenase, lactate dehydrogenase and glyceraldehyde-3-phosphate dehydrogenase. (1980) (21)
Structure of the complex of active site metal‐depleted horse liver alcohol dehydrogenase and NADH. (1983) (21)
Identification of the stable free radical tyrosine residue in ribonucleotide reductase (1985) (21)
Copper amine oxidase: a novel use for a tyrosine. (1995) (20)
Amino acid sequence determination and three-dimensional modelling of thioredoxin from the photosynthetic bacterium Rhodobacter sphaeroides Y. (1988) (19)
Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding (2007) (18)
Crystallization and preliminary crystallographic data of ribonucleotide reductase protein B2 from Escherichia coli. (1984) (17)
Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme (2005) (16)
Reactivity of the tyrosyl radical of Escherichia coli ribonucleotide reductase -- control by the protein. (1997) (16)
Functional studies of active‐site mutants from Drosophila melanogaster deoxyribonucleoside kinase (2007) (16)
The structure of a reduced mutant T4 glutaredoxin (1995) (16)
Structural studies of horse liver alcohol dehydrogenase: Coenzyme, substrate and inhibitor binding (1983) (16)
NO binding to naphthalene dioxygenase (2005) (15)
Structure of Escherichia coli YhdH, a putative quinone oxidoreductase. (2004) (15)
Coenzyme binding in alcohol dehydrogenase. (1989) (15)
Structure-function analysis of a bacterial deoxyadenosine kinase reveals the basis for substrate specificity. (2007) (14)
Structure of liver alcohol dehydrogenase at 2.9-angstrom resolution. (1973) (14)
Reduction of mutant phage T4 glutaredoxins by Escherichia coli thioredoxin reductase. (1993) (14)
Drosophila melanogaster deoxyribonucleoside kinase activates gemcitabine. (2009) (14)
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (2008) (13)
Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D (2005) (12)
Coenzyme-induced conformational changes and substrate binding in liver alcohol dehydrogenase. (1977) (11)
On the molecular mechanism of liver alcohol dehydrogenase: Monte Carlo simulations and X-ray studies of water in the substrate channel. (1986) (10)
Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 (2010) (10)
Three-dimensional structures of MDR alcohol dehydrogenases (2008) (9)
Electrostatic effects of bound NADH and NAD+ on ionizing groups in liver alcohol dehydrogenase. (1987) (9)
Crystallographic investigations of ribonucleotide reductase. (1993) (8)
Crystallographic investigation of the dependence of calcium and phosphate ions for notexin (1997) (7)
A single-residue exchange gives human recombinant beta beta alcohol dehydrogenase gamma gamma isozyme properties. (1992) (6)
Preliminary crystallographic data for an extracellular proteolytic enzyme from a strain of arthrobacter. (1968) (6)
X-ray Structure of Benzoate Dioxygenase Reductase (2002) (6)
Site-directed mutagenesis of mammalian alcohol and sorbitol dehydrogenases map functional differences within the enzyme family. (1993) (6)
Comparison of computer modelling and X-ray results of the binding of a pyrazole derivative to liver alcohol dehydrogenase. (1987) (6)
An elongated form of T4 glutaredoxin with four extra residues. (1993) (5)
Protein B1 of ribonucleotide reductase. Direct analytical data and comparisons with data indirectly deduced from the nucleotide sequence of the Escherichia coli nrdA gene. (1985) (5)
Crystallization and Crystallographic Investigations of Ferredoxin:Thioredoxin Reductase from Synechocystis SP. PCC6803 (1998) (4)
Crystallographic investigations of alcohol dehydrogenases. (1994) (4)
The ten-stranded beta/alpha barrel in ribonucleotide reductase protein R1. (1996) (4)
Light/Dark Regulation of Chloroplast Metabolism (2007) (4)
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 BETA CHAIN (1997) (3)
Crystallizations of novel forms of alcohol dehydrogenase. (1995) (3)
Computer-graphics interpretations of residue exchanges between the alpha, beta and gamma subunits of human-liver alcohol dehydrogenase class I isozymes. (1987) (3)
The crystal structure of nitrobenzene 1,2-dioxygenase (2003) (3)
Enantioselective affinity labelling of horse liver alcohol dehydrogenase. Correlation of inactivation kinetics with the three-dimensional structure of the enzyme. (1983) (3)
Three-Dimensional Structure of the Horse Liver Alcohol Dehydrogenase Molecule (1974) (2)
Structural basis for substrate specificities of cellular deoxyribosenucleoside kinases - correction (2001) (2)
Crystal structures of naphthalene dioxygenase along the reaction pathway (2003) (2)
Structure of aromatic-ring-hydroxylating dioxygenasean - Naphthalene 1,2-dioxygenase (1999) (1)
Crystal structure of thioredoxin from Trypanosoma brucei brucei (2003) (1)
Structure and function of ribonucleotide reductase R1 protein (1996) (1)
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN MUTANT Y730F WITH A REDUCED ACTIVE SITE FROM ESCHERICHIA COLI (1998) (0)
Crystallographic studies of ribonucleotide reductase from Salmonella typhimurium. Clues about the allosteric regulation (2002) (0)
STRUCTURE OF NADPH DEPENDENT THIOREDOXIN REDUCTASE (1997) (0)
The structure of the iron centre of ribonucleotide reductase and its implications for the formation of a stable free tyrosine radical (1991) (0)
NAPHTHALENE 1,2-DIOXYGENASE WITH INDOLE BOUND IN THE ACTIVE SITE. (2000) (0)
Thymidine kinase of mycoplasmic origin - an enzyme with lasso (2005) (0)
Active site mutant of dNK from D. melanogaster with dTTP bound (2007) (0)
Crystal Structure of Thymidine Kinase with dTTP from U. urealyticum (2004) (0)
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH SUBSTRATE, GDP AND EFFECTOR DTTP FROM ESCHERICHIA COLI (1998) (0)
Structure of deoxyadenosine kinase from M.mycoides with products dcmp and a flexible dcdp bound (2007) (0)
FLAVODOXIN REDUCTASE FROM E. COLI (1997) (0)
Crystallization and preliminary structure analysis of protein R2 mutants of Escherichia coli ribonucleotide reductase (1993) (0)
NAPHTHALENE 1,2-DIOXYGENASE, TERNARY COMPLEX WITH DIOXYGEN AND INDOLE (2003) (0)
Mutation Study of Two Thymidine Kinases : An Attempt to Create an Enzyme that Effectively Activates Anticancer and Antiviral Nucleoside Analogs (2007) (0)
Crystal structure of Drosophila deoxyribonucleotide kinase complexed with the substrate deoxythymidine (2003) (0)
Conformational changes of alcohol dehydrogenase (1981) (0)
ALCOHOL DEHYDROGENASE (E.C.1.1.1.1) (EE ISOZYME) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD), AND ZINC (1996) (0)
BETAINE ALDEHYDE DEHYDROGENASE FROM COD LIVER (1998) (0)
RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM (OXIDIZED) (1999) (0)
Exploring the active site of the multifunctional Drosophila deoxynucleoside kinase complexed with several medically interesting nucleoside analogues as Gemzar, Zalcitabine, Floxuridine and BVDU (2006) (0)
Crystal srtucture of the binary complex between ferredoxin: thioredoxin reductase and thioredoxin f (2007) (0)
Crystal Structure of Human Deoxyguanosine Kinase (2007) (0)
RIBONUCLEOTIDE REDUCTASE R2F PROTEIN FROM SALMONELLA TYPHIMURIUM (1999) (0)
Thymidine kinase from B. anthracis in complex with dT. (2007) (0)
Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine (2005) (0)
NAPHTHALENE 1,2-DIOXYGENASE, PRODUCT COMPLEX (2003) (0)
Structure of Human Thymidine Kinase 1 – Using a Lasso to Catch a Base (2006) (0)
CRYSTAL STRUCTURE OF A MUTANT ESCHERICHIA COLI THIOREDOXIN WITH AN ARGININE INSERTION IN THE ACTIVE SITE (1993) (0)
NAPHTHALENE 1,2-DIOXYGENASE WITH NITRIC OXIDE AND INDOLE BOUND IN THE ACTIVE SITE. (2005) (0)
Thymidine kinase from B. cereus with TTP bound as phosphate donor. (2007) (0)
Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP (2005) (0)
Molecular, Electronic, and Structural Aspects of the Catalytic Mechanism of Alcohol Dehydrogenases (2018) (0)
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH DTTP OCCUPYING THE SPECIFICITY SITE FROM ESCHERICHIA COLI (1998) (0)
The iron center in ribonucleotide reductase (1993) (0)
Structure of the Thioredoxin 2 from Anabaena sp. pcc7120 (1995) (0)
RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI (1998) (0)
PROTEIN R2 OF RIBONUCLEOTIDE REDUCTASE FROM MOUSE (1997) (0)
The Crystal Structure of Nitrobenzene Dioxygenase in complex with 3- nitrotoluene (2005) (0)
NOTEXIN, A PRESYNAPTIC NEUROTOXIC PHOSPHOLIPASE A2 (1997) (0)
Structure of the Escherichia Coli Yhdh, a Putative Quinone Oxidoreductase (2004) (0)
Alcohol dehydrogenase: more structures – implications to specificity and function (1996) (0)
Editorial overview: Current opinion in structural biology 1993, 3: 813–814 (1993) (0)
Crystal structure of Toluene 2,3-Dioxygenase (2009) (0)
Structure of deoxyadenosine kinase from M.mycoides with bound dATP (2007) (0)
NAPHTHALENE 1,2-DIOXYGENASE, BINARY COMPLEX WITH DIOXYGEN (2003) (0)
RIBONUCLEOTIDE REDUCTASE E441A MUTANT R1 PROTEIN FROM ESCHERICHIA COLI (1998) (0)
NAPHTHALENE 1,2-DIOXYGENASE WITH OXIDIZED RIESKE IRON SULPHUR CENTER SITE. (2003) (0)
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP (2003) (0)
Crystal Structure of Human Thymidine Kinase 1 (2004) (0)
Properties of the B2 subunit in Escherichia coli ribonucleotide reductase (1989) (0)
Pectin methylesterase from Carrot (2002) (0)
Human phosphoribosyl transferase domain containing 1 (2006) (0)
NAPHTHALENE 1,2-DIOXYGENASE WITH NAPHTHALENE BOUND IN THE ACTIVE SITE. (2003) (0)
NAPHTHALENE 1,2-DIOXYGENASE WITH NITRIC OXIDE BOUND IN THE ACTIVE SITE. (2005) (0)
Ribonucleotide Reductase Protein R1E from Salmonella typhimurium (2004) (0)
Crystal structure of Toluene 2,3-Dioxygenase Ferredoxin (2009) (0)
Spotlight on... Hans Eklund. Interview by Daniela Ruffell. (2008) (0)
NAPHTHALENE 1,2-DIOXYGENASE, FULLY REDUCED FORM (2003) (0)
Crystal Structure of Drosophila Deoxyribonucleoside Kinase (2001) (0)
Replication of an RNA ligase ribozyme under alternating temperature condition. (2007) (0)
NOTECHIS II-5, NEUROTOXIC PHOSPHOLIPASE A2 FROM NOTECHIS SCUTATUS SCUTATUS (1997) (0)
Three-dimensional structure of Escherichia coli thioredoxin-S2 to 2.8 A resolution (1975) (0)
CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE (2000) (0)
Structural studies on alcohol dehydrogenases and inhibitor complexes (1993) (0)
Investigation of active site mutants of Drosophila melanogaster deoxyribonucleoside kinase - a kinetic and structural study (2006) (0)
ANTICOAGULANT CLASS II PHOSPHOLIPASE A2 FROM THE VENOM OF VIPERA RUSSELLI RUSSELLI (1997) (0)
Crystal structure of Toluene 2,3-Dioxygenase Reductase (2009) (0)

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What Schools Are Affiliated With Hasse Eklund?

Hasse Eklund is affiliated with the following schools:

Swedish University of Agricultural Sciences