Har Gobind Khorana | Academic Influence

Har Gobind Khorana's AcademicInfluence.com Rankings

Har Gobind Khorana

Biology

#25

World Rank

#48

Historical Rank

#17

USA Rank

Biochemistry

#8

World Rank

#11

Historical Rank

#5

USA Rank

Molecular Biology

#37

World Rank

#37

Historical Rank

#25

USA Rank

Genetics

#35

World Rank

#58

Historical Rank

#25

USA Rank

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Biology

Har Gobind Khorana's Degrees

PhD Chemistry University of Liverpool

Why Is Har Gobind Khorana Influential?

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According to Wikipedia, Har Gobind Khorana was an Indian-American biochemist. While on the faculty of the University of Wisconsin–Madison, he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and Robert W. Holley for research that showed the order of nucleotides in nucleic acids, which carry the genetic code of the cell and control the cell's synthesis of proteins. Khorana and Nirenberg were also awarded the Louisa Gross Horwitz Prize from Columbia University in the same year.

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Har Gobind Khorana's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Requirement of Rigid-Body Motion of Transmembrane Helices for Light Activation of Rhodopsin (1996) (1150)
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. (1989) (595)
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line (2002) (579)
Nucleoside Polyphosphates. X.1 The Synthesis and Some Reactions of Nucleoside-5' Phosphoromorpholidates and Related Compounds. Improved Methods for the Preparation of Nucleoside-5' Polyphosphates1 (1961) (424)
Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212. (1988) (421)
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants. (1990) (417)
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. (1987) (409)
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. (1994) (387)
The Chemistry of Carbodiimides. (1953) (380)
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin. (1988) (373)
Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases. (1971) (367)
Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function. (1992) (360)
Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking. (2003) (358)
Rhodopsin mutants that bind but fail to activate transducin. (1990) (348)
Studies on Polynucleotides. XXIV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (4).2 Protected Derivatives of Deoxyribonucleosides and New Syntheses of Deoxyribonucleoside-3″ Phosphates3 (1963) (347)
Amino acid sequence of bacteriorhodopsin. (1979) (330)
Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments. (1981) (301)
Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. (1994) (298)
Assembly of functional rhodopsin requires a disulfide bond between cysteine residues 110 and 187. (1990) (294)
Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin. (1992) (267)
Studies on polynucleotides (1965) (266)
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. (1996) (264)
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin. (1989) (260)
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines. (1989) (245)
Studies on Polynucleotides. XIV.1 Specific Synthesis of the C3"-C5" Interribonucleotide Linkage. Syntheses of Uridylyl-(3"5")-Uridine and Uridylyl-(3"5")-Adenosine2 (1962) (243)
Nucleoside Polyphosphates. XI.1 An Improved General Method for the Synthesis of Nucleotide Coenzymes. Syntheses of Uridine-5', Cytidine-5' and Guanosine-5' Diphosphate Derivatives (1961) (241)
Studies on polynucleotides. III. Enzymic degradation; substrate specificity and properties of snake venom phosphodiesterase. (1959) (236)
Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups. (1977) (222)
Aspartic acid substitutions affect proton translocation by bacteriorhodopsin. (1988) (215)
A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. (1988) (210)
Structure and function in rhodopsin: the role of asparagine-linked glycosylation. (1994) (205)
Bacteriorhodopsin, a membrane protein that uses light to translocate protons. (1988) (203)
Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures. (1982) (203)
Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants (2002) (198)
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. (1973) (195)
Structure and Function in Rhodopsin (1995) (194)
Carbodiimides. VIII.1 Observations on the Reactions of Carbodiimides with Acids and Some New Applications in the Synthesis of Phosphoric Acid Esters (1958) (184)
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. (1990) (182)
The bacteriorhodopsin gene. (1981) (180)
Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin. (1991) (179)
Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast (1970) (178)
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA. (1967) (178)
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study. (1995) (164)
Identification of core amino acids stabilizing rhodopsin. (2004) (163)
Studies on Polynucleotides. I. A New and General Method for the Chemical Synthesis of the C5″-C3″ Internucleotidic Linkage. Syntheses of Deoxyribo-dinucleotides1 (1958) (158)
Cyclic Phosphates. IV.1 Ribonucleoside-3',5' Cyclic Phosphates. A General Method of Synthesis and Some Properties (1961) (157)
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. (1989) (156)
Polynucleotide synthesis and the genetic code. (1966) (151)
Designer short peptide surfactants stabilize G protein-coupled receptor bovine rhodopsin (2006) (149)
Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops. (2005) (146)
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: Use of a photoactivatable reagent (2001) (145)
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. (1994) (142)
Total synthesis of a gene (1979) (142)
Palmitoylation of bovine opsin and its cysteine mutants in COS cells. (1993) (142)
Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa. (1996) (141)
A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates. (1966) (138)
CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast (1972) (137)
Protonation state of Asp (Glu)-85 regulates the purple-to-blue transition in bacteriorhodopsin mutants Arg-82----Ala and Asp-85----Glu: the blue form is inactive in proton translocation. (1990) (136)
Studies on Polynucleotides. VIII.1Experiments on the Polymerization of Mononucleotides. Improved Preparation and Separation of Linear Thymidine Polynucleotides. Synthesis of Corresponding Members Terminated in Deoxycytidine Residues2 (1961) (135)
Nucleic acid synthesis (1968) (133)
Role of the intradiscal domain in rhodopsin assembly and function. (1990) (132)
Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers. (1967) (130)
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. (1994) (127)
Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk. (1995) (126)
High-pressure liquid chromatography in polynucleotide synthesis. (1978) (126)
Total synthesis of a gene for bovine rhodopsin. (1986) (126)
Mechanism of light-dependent proton translocation by bacteriorhodopsin (1993) (121)
Studies on Polynucleotides. LII.1 The Use of 2,4,6-Triisopropylbenzenesulfonyl Chloride for the Synthesis of Internucleotide Bonds2 (1966) (120)
Anderegg, R. J.,Nihei, K.,and Biemann Amino acid sequence of bacteriorhodopsin (1979) (118)
The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa. (1991) (117)
Nucleoside Polyphosphates. VI.1 An Improved and General Method for the Synthesis of Ribo- and Deoxyribonucleoside 5'-Triphosphates (1958) (117)
Nucleoside Polyphosphates. XII.1 The Total Synthesis of Coenzyme A2 (1961) (116)
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. (1993) (116)
Structure of the lipopolysaccharide from an Escherichia coli heptose-less mutant. I. Chemical degradations and identification of products. (1979) (115)
Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. (1965) (115)
NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. (1999) (114)
Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins. (1979) (113)
Studies on Polynucleotides. II.1 The Synthesis and Characterization of Linear and Cyclic Thymidine Oligonucleotides2 (1958) (109)
Site of attachment of retinal in bacteriorhodopsin. (1981) (108)
Pyrophosphorylation of ribose 5-phosphate in the enzymatic synthesis of 5-phosphorylribose 1-pyrophosphate. (1958) (108)
CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50. (1972) (107)
Mapping of contact sites in complex formation between light-activated rhodopsin and transducin by covalent crosslinking: Use of a chemically preactivated reagent (2001) (106)
GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence. (1985) (102)
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID, XVI. OLIGONUCLEOTIDES AS TEMPLATES AND THE MECHANISM OF THEIR REPLICATION. (1964) (102)
Orientation of retinal in bovine rhodopsin determined by cross-linking using a photoactivatable analog of 11-cis-retinal. (1990) (101)
Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study. (1999) (100)
Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines. (1996) (100)
Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. (2004) (99)
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1. (2001) (99)
Studies on polynucleotides. 48. The in vitro synthesis of a co-polypeptide containing two amino acids in alternating sequence dependent upon a DNA-like polymer containing two nucleotides in alternating sequence. (1965) (98)
Changes in interhelical hydrogen bonding upon rhodopsin activation. (2005) (98)
Studies on polynucleotides. IV. Enzymic degradation; the stepwise action of venom phosphodiesterase on deoxyribo-oligonucleotides. (1959) (97)
Nucleoside Polyphosphates. VIII.1 New and Improved Syntheses of Uridine Diphosphate Glucose and Flavin Adenine Dinucleotide Using Nucleoside-5' Phosphoramidates2 (1958) (97)
Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons. (1984) (97)
Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface. (2006) (95)
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state. (1997) (94)
Structural features of the C-terminal domain of bovine rhodopsin: a site-directed spin-labeling study. (1999) (94)
Intermediates in the folding of the membrane protein bacteriorhodopsin (1995) (93)
Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. (1997) (93)
Cyclic Phosphates. III. Some General Observations on the Formation and Properties of Five-, Six- and Seven-membered Cyclic Phosphate Esters (1957) (91)
Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8. (2001) (91)
Regeneration of the native bacteriorhodopsin structure from two chymotryptic fragments. (1983) (91)
Some recent developments in the chemistry of phosphate esters of biological interest (1961) (90)
Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels. (1996) (90)
Purification and properties of a pyrimidine deoxyriboside phosphorylase from Escherichia coli. (1958) (89)
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation. (1991) (89)
High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. (1983) (88)
Specificity of sRNA for recognition of codons as studied by the ribosomal binding technique. (1966) (88)
Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains. (1984) (88)
Reversal of bacteriophage T4 induced polynucleotide kinase action. (1973) (88)
Location of the Retinal Chromophore in the Activated State of Rhodopsin* (2009) (87)
Studies on polynucleotides, C. A novel joining reaction catalyzed by the T4-polynucleotide ligase. (1970) (87)
Two light-transducing membrane proteins: bacteriorhodopsin and the mammalian rhodopsin. (1993) (87)
The amino acid sequence of a glutamic acid-rich protein from bovine retina as deduced from the cDNA sequence. (1991) (86)
Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli. (1987) (86)
Structure-Function Studies on Bacteriorhodopsin (1987) (85)
Studies on Polynucleotides. XI.1 Chemical Polymerization of Mononucleotides. The Synthesis and Characterization of Deoxyadenosine Polynucleotides2 (1961) (85)
Structural features and light-dependent changes in the sequence 59-75 connecting helices I and II in rhodopsin: a site-directed spin-labeling study. (1999) (85)
CXII. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized polydeoxynucleotides to form the DNA duplex representing nucleotide sequence 1 to 20. (1972) (84)
Light-stable rhodopsin. I. A rhodopsin analog reconstituted with a nonisomerizable 11-cis retinal derivative. (1992) (83)
Structure and function in rhodopsin. Requirements of a specific structure for the intradiscal domain. (1994) (82)
Structure and function in rhodopsin. Single cysteine substitution mutants in the cytoplasmic interhelical E-F loop region show position-specific effects in transducin activation. (1996) (82)
Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine‐185 protonates and deprotonantes during the photocycle (1988) (81)
Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function. (1999) (81)
Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences. (1965) (80)
Expression of a bovine rhodopsin gene in Xenopus oocytes: demonstration of light-dependent ionic currents. (1988) (79)
Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin (2001) (78)
The transmembrane domain of glycophorin A as studied by cross-linking using photoactivatable phospholipids. (1982) (78)
Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure. (1999) (77)
Studies on Polynucleotides. XVI.1 Specific Synthesis of the C3″-C5″ Interribonucleotidic Linkage. Examination of Routes Involving Protected Ribonucleosides and Ribonucleoside-3″ Phosphates. Syntheses of Uridylyl-(3″→5″)-adenosine, Uridylyl-(3″→5″)-cytidine, Adenylyl-(3″→5″)-adenosine and Related Com (1962) (77)
Opsin stability and folding: modulation by phospholipid bicelles. (2007) (76)
Orientation of bacteriorhodopsin in Halobacterium halobium as studied by selective proteolysis. (1977) (75)
Detection of a water molecule in the active-site of bacteriorhodopsin: hydrogen bonding changes during the primary photoreaction. (1994) (75)
Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation. (1989) (75)
Orientation of retinal in bacteriorhodopsin as studied by cross-linking using a photosensitive analog of retinal. (1982) (74)
Studies on Polynucleotides. XXXIV.1 The Specific Synthesis of C3'-C5'-Linked Ribooligonucleotides.2 New Protected Derivatives of Ribonucleosides and Ribonucleoside 3'-Phosphates. Further Syntheses of Diribonucleoside Phosphates3 (1964) (72)
Polynucleotide ligase-catalyzed joining of deoxyribo-oligonucleotides on ribopolynucleotide templates and of ribo-oligonucleotides on deoxyribopolynucleotide templates. (1970) (71)
Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. (1967) (71)
Light-stable rhodopsin. II. An opsin mutant (TRP-265----Phe) and a retinal analog with a nonisomerizable 11-cis configuration form a photostable chromophore. (1992) (71)
Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C. (1996) (70)
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization. (1991) (70)
Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants (2001) (70)
Studies on Polynucleotides. IX.1 Experiments on the Polymerization of Mononucleotides. Certain Protected Derivatives of Deoxycytidine-5' Phosphate and the Synthesis of Deoxycytidine Polynucleotides2 (1961) (69)
Structure-function studies on bacteriorhodopsin. II. Improved expression of the bacterio-opsin gene in Escherichia coli. (1987) (69)
Studies on Polynucleotides. XVII.1 On the Mechanism of Internucleotide Bond Synthesis by the Carbodiimide Method2 (1962) (69)
Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase. (1999) (68)
Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid. (1980) (67)
Structure and thermal stability of monomeric bacteriorhodopsin in mixed pospholipid/detergent micelles (1989) (67)
Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F. (1987) (67)
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast (1971) (67)
Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation. (1987) (66)
Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. (1966) (66)
Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line. (1999) (66)
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk. (1994) (66)
Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle. (1989) (65)
The retinylidene Schiff base counterion in bacteriorhodopsin. (1991) (65)
Secondary Structure and Aggregation in Deoxyguanosine Oligonucleotides (1962) (65)
Chemical synthesis of polynucleotides. (1972) (65)
cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. (1985) (64)
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that ASP-96 deprotonates during the M----N transition. (1991) (64)
Reconstitution of delipidated bacteriorhodopsin with endogenous polar lipids. (1981) (63)
Structure and function in rhodopsin. Separation and characterization of the correctly folded and misfolded opsins produced on expression of an opsin mutant gene containing only the native intradiscal cysteine codons. (1995) (63)
Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid (1991) (63)
Deoxyribooligonucleotide Synthesis on a Polymer Support1 (1966) (62)
Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin. (1989) (62)
Gene replacement in Halobacterium halobium and expression of bacteriorhodopsin mutants. (1993) (62)
The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids. (1983) (62)
Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin. (1989) (61)
Studies on Polynucleotides. VI.1Experiments on the Chemical Polymerization of Mononucleotides. Oligonucleotides Derived from Thymidine-3' Phosphate2 (1959) (60)
Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR. (2004) (60)
Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin (1994) (59)
Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation. (1999) (59)
Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids. (1989) (59)
Studies on Polynucleotides. XX.1Amino Acid Acceptor Ribonucleic Acids (1). The Synthesis and Properties of 2″ (or 3″)-O-(DL-Phenylalanyl)-adenosine, 2″ (or 3″)-O-(DL-Phenylalanyl)-uridine and Related Compounds2 (1963) (58)
The membrane-embedded segment of cytochrome b5 as studied by cross-linking with photoactivatable phospholipids. II. The nontransferable form. (1983) (58)
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. (1997) (58)
Studies on polynucleotides. LXXII. Deoxyribooligonucleotide synthesis on a polymer support. (1967) (57)
Sites of interaction in the complex between beta- and gamma-subunits of transducin. (1990) (57)
Studies on Polynucleotides. XXX.1 A Comparative Study of Reagents for the Synthesis of the C3′-C5′ Internucleotidic Linkage2 (1964) (57)
Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites. (1994) (56)
Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket. (1999) (55)
Resonance Raman microprobe spectroscopy of rhodopsin mutants: effect of substitutions in the third transmembrane helix. (1992) (55)
Regeneration of native bacteriorhodopsin structure from fragments. (1984) (54)
CHEMICALLY SYNTHESIZED DEOXYPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE. (1963) (54)
Structure-function studies on bacteriorhodopsin. III. Total synthesis of a gene for bacterio-opsin and its expression in Escherichia coli. (1987) (53)
465. Studies on phosphorylation. Part XI. The reaction between carbodi-imides and acid esters of phosphoric acid. A new method for the preparation of pyrophosphates (1953) (52)
Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. (1967) (52)
Amino acid sequence of the membranous segment of rabbit liver cytochrome b5. Methodology for separation of hydrophobic peptides. (1980) (52)
Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin. (1993) (51)
Solution NMR spectroscopy of [α-15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence (2002) (51)
Carbodiimides. VII.1Tetra-p-nitrophenyl Pyrophosphate, a New Phosphorylating Agent (1957) (51)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. (1976) (50)
Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin (2004) (49)
Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 2. Rotational orientation of helices D and E and kinetic correlation between M formation and proton release in bacteriorhodopsin micelles. (1994) (49)
Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin. (2001) (48)
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that Thr-46 and Thr-89 form part of a transient network of hydrogen bonds. (1992) (47)
Carbodiimides. Part V.1 A Novel Synthesis of Adenosine Di- and Triphosphate and P1,P2-Diadenosine-5'-pyrophosphate (1954) (47)
Chemical synthesis and cloning of a tyrosine tRNA gene. (1979) (46)
Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence for the interaction of aspartic acid 212 with tyrosine 185 and possible role in the proton pump mechanism. (1990) (45)
Nucleotide sequence studies on yeast phenylalanine sRNA. (1966) (45)
Carbodiimides. VI. The Reaction of Dicyclohexylcarbodiimide with Yeast Adenylic Acid. A New Method for the Preparation of Monoesters of Ribonucleoside 2'- and 3'-Phosphates (1954) (44)
Acetyl phosphatidylethanolamine in the reconstitution of ion pumps. (1975) (44)
Role of group-conserved residues in the helical core of β2-adrenergic receptor (2007) (44)
Studies on Polynucleotides. XIX.1 The Specific Synthesis of C3″-C5″ Inter-ribonucleotidic Linkage.2 A New Approach and its Use in the Synthesis of C3″-C5″-Linked Uridine Oligonucleotides3 (1963) (43)
Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene. (1974) (43)
Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis. (1967) (43)
Studies on Polynucleotides. XIII.1Stepwise Synthesis of Deoxyribo-oligonucleotides. An Alternative General Approach and the Synthesis of Thymidine Di-, Tri- and Tetranucleotides Bearing 3"-Phosphomonoester End Groups2 (1962) (43)
Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics. (2001) (42)
Removal of the carboxyl-terminal peptide does not affect refolding or function of bacteriorhodopsin as a light-dependent proton pump. (1984) (42)
Studies on Polynucleotides CXVIII. A FURTHER STUDY OF RIBONUCLEOTIDE INCORPORATION INTO DEOXYRIBONUCLEIC ACID CHAINS BY DEOXYRIBONUCLEIC ACID POLYMERASE I OF ESCHERICHIA COLI (1972) (42)
The reaction of hydroxylamine with bacteriorhodopsin studied with mutants that have altered photocycles: selective reactivity of different photointermediates. (1991) (41)
Intermolecular crosslinking of fatty acyl chains in phospholipids: use of photoactivable carbene precursors. (1979) (41)
Immunological probes for bacteriorhodopsin. Identification of three distinct antigenic sites on the cytoplasmic surface. (1982) (41)
Identification of the lipid-binding site of phosphatidylcholine-transfer protein with phosphatidylcholine analogs containing photoactivable carbene precursors. (1983) (41)
Uv-visible spectroscopy of bacteriorhodopsin mutants: substitution of Arg-82, Asp-85, Tyr-185, and Asp-212 results in abnormal light-dark adaptation. (1990) (41)
A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. (1982) (41)
Studies on polynucleotides. The linkage of deoxyribopolynucleotide templates to cellulose and its use in their replication. (1974) (40)
Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase. (1997) (40)
THE TOTAL SYNTHESIS OF COENZYME A (1959) (40)
Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M. (2000) (40)
Nucleoside Polyphosphates. IV.1 A New Synthesis of Guanosine 5'-Phosphate (1957) (40)
The site of attachment of retinal in bacteriorhodopsin. A resonance Raman study. (1982) (40)
Structure and function in rhodopsin: Asymmetric reconstitution of rhodopsin in liposomes (2002) (39)
Effects of amino acid substitutions in the F helix of bacteriorhodopsin. Low temperature ultraviolet/visible difference spectroscopy. (1988) (39)
Studies on Polynucleotides. XVIII.1 Experiments on the Polymerization of Mononucleotides. The Synthesis and Characterization of Deoxyguanosine Oligonucleotides2 (1963) (39)
Nucleoside Polyphosphates. III.1 Syntheses of Pyrimidine Nucleoside-2'(3'),5'-diphosphates (1955) (39)
The Synthesis of 9-α-D-Ribofuranosyladenine (1958) (38)
NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation. (2004) (38)
Studies on polynucleotides. CXVI. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends. (1972) (38)
Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence. (1966) (37)
Study on polynucleotideCV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50 (1972) (37)
The mode of action of ryegrass ribonuclease. (1959) (37)
Deoxyribonucleic acid synthesis in cell-free extracts. 3. Catalytic properties of deoxyribonucleic acid polymerase II. (1972) (37)
Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base. (1992) (37)
Vibrational spectroscopy of bacteriorhodopsin mutants: chromophore isomerization perturbs tryptophan-86. (1989) (37)
Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes. (1968) (37)
Conserved amino acids in F‐helix of bacteriorhodopsin form part of a retinal binding pocket (1989) (36)
Studies on Polynucleotides. XII.1 Experiments on the Polymerization of Mononucleotides. A Comparison of Different Polymerizing Agents and a General Improvement in the Isolation of Synthetic Polynucleotides2 (1962) (36)
Asp96 deprotonation and transmembrane alpha-helical structural changes in bacteriorhodopsin. (1993) (36)
Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries. (1991) (36)
Fatty acids containing photoactivable carbene precursors. Synthesis and photochemical properties of 3,3-bis(1,1-difluorohexyl)diazirine and 3-(1,1-difluorooctyl)-3H-diazirine (1980) (36)
SYNTHETIC DEOXYRIBO-OLIGONUCLEOTIDES AS TEMPLATES FOR THE DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE L-POLYMERS CONTAINING REPEATING NUCLEOTIDE SEQUENCES. (1965) (34)
Studies on polynucleotides. CII. The use of aromatic isocyanates for selective blocking of the terminal 3'-hydroxyl group in protected deoxyribooligonucleotides. (1972) (34)
Synthesis in the study of nucleic acids. The Fourth Jubilee Lecture. (1968) (34)
Structure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiae. (1996) (34)
Combined solid state and solution NMR studies of α,ɛ-15N labeled bovine rhodopsin (2007) (34)
Studies on Polynucleotides. LXII.1 Deoxyribopolynucleotides Containing Repeating Trinucleotide Sequences (4).2 Preparation of Suitably Protected Deoxyribotrinucleotides3 (1967) (33)
Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements. (1995) (33)
Total synthesis of a tyrosine suppressor transfer RNA gene. XVII. Transcription, in vitro, of the synthetic gene and processing of the primary transcript to transfer RNA. (1979) (33)
Structure and function in rhodopsin: destabilization of rhodopsin by the binding of an antibody at the N-terminal segment provides support for involvement of the latter in an intradiscal tertiary structure. (2000) (33)
Structure-function studies of bacteriorhodopsin XV. Effects of deletions in loops B-C and E-F on bacteriorhodopsin chromophore and structure. (1991) (33)
Studies on Polynucleotides. XXV.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (5).1 Further Studies on the Synthesis of Internucleotide Bond by the Carbodiimide Method. The Synthesis of Suitably Protected Dinucleotides as Intermediates in the Synthesis of Higher Oligonucleotides3 (1963) (32)
Sites of intermolecular crosslinking of fatty acyl chains in phospholipids carrying a photoactivable carbene precursor. (1979) (32)
Studies on Polynucleotides. XXVIII.1The Specific Synthesis of C3″-C5″-Linked Ribooligonucleotides (4).2The Stepwise Synthesis of Uridylyl-(3″ → 5″)-adenylyl-(3″ → 5″)-uridylyl-(3″ → 5″)-uridine3 (1963) (32)
High-Level Expression, Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD81 (2008) (32)
The structure of lipopolysaccharide from an Escherichia coli heptose-less mutant. III. Two fatty acyl amidases from Dictyostelium discoideum and their action on lipopolysaccharide derivatives. (1979) (32)
Synthesis of a gene for sensory rhodopsin I and its functional expression in Halobacterium halobium. (1993) (31)
Bacteriorhodopsin precursor. Characterization and its integration into the purple membrane. (1984) (31)
Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore. (1990) (31)
Nucleoside Polyphosphates. VII.1The Use of Phosphoramidic Acids in the Synthesis of Nucleoside-5' Pyrophosphates (1958) (30)
Phosphorylated Sugars. V.1 Syntheses of Arabinofuranose and Arabinopyranose 1-Phosphates (1958) (30)
Light-driven proton translocation by bacteriorhodopsin reconstituted with the phenyl analog of retinal. (1981) (30)
SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE FORMATION AND CHARACTERIZATION OF A RIBOPOLYNUCLEOTIDE WITH A REPEATING TRINUCLEOTIDE SEQUENCE. (1964) (30)
Studies on Polynucleotides. LXV.1 The Synthesis of Deoxyribopolynucleotides Containing Repeating Tetranucleotide Sequences (2)2 (1967) (30)
452. The chemistry of the melanins. Part I. The synthesis of 5 : 6-dihydroxyindole and related compounds (1948) (30)
Studies on polynucleotides, 88. Enzymatic joining of chemically synthesized segments corresponding to the gene for alanine-tRNA. (1968) (30)
Structure and function in rhodopsin: the fate of opsin formed upon the decay of light-activated metarhodopsin II in vitro. (1995) (30)
Missense suppression of the tryptophan synthetase A-protein mutant A78. (1966) (30)
Retinitis Pigmentosa Rhodopsin Mutations L125R and A164V Perturb Critical Interhelical Interactions (2003) (29)
Studies on Polynucleotides. LX.1 The Use of Preformed Dinucleotide Blocks in Stepwise Synthesis of Deoxyribopolynucleotides2 (1967) (29)
THE STEPWISE DEGRADATION OF THYMIDINE OLIGONUCLEOTIDES BY SNAKE VENOM AND SPLEEN PHOSPHODIESTERASES (1958) (29)
387. Peptides. Part III. Selective degradation from the carboxyl end. The use of carbodi-imides (1952) (29)
Expression of the archaebacterial bacterio-opsin gene with and without signal sequences in Escherichia coli: the expressed proteins are located in the membrane but bind retinal poorly. (1990) (28)
Studies on polynucleotides. LXIII. Deoxyribopolynucleotides containing repeating trinucleotide sequences. The polymerization of protected deoxyribotrinucleotides (1967) (28)
SYNTHESES OF DIDEOXYRIBONUCLEOTIDES (1957) (28)
A Transposable Element from Halobacterium Halobium which Inactivates the Bacteriorhodopsin Gene (1982) (28)
STUDIES ON POLYNUCLEOTIDES, LIX. FURTHER CODON ASSIGNMENTS FROM AMINO ACID INCORPORATIONS DIRECTED BY RIBOPOLYNUCLEOTIDES CONTAINING REPEATING TRINUCLEOTIDE SEQUENCES* (1966) (28)
Cyclic Phosphates. II. Further Studies of Ribonucleoside 2':3'-Cyclic Phosphates1 (1955) (28)
The site of attachment of retinal in bacteriorhodopsin. The epsilon-amino group in Lys-41 is not required for proton translocation. (1982) (28)
Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain. (2007) (28)
Studies on Polynucleotides. XXIX.1The Specific Synthesis of C3″-C5″-Linked Ribooligonucleotides(5).2Homologous Adenine Oligonucleotides3 (1963) (27)
CARBODIIMIDES: PART III. (A) A NEW METHOD FOR THE PREPARATION OF MIXED ESTERS OF PHOSPHORIC ACID. (B) SOME OBSERVATIONS ON THE BASE-CATALYZED ADDITION OF ALCOHOLS TO CARBODIIMIDES (1954) (27)
Studies on polynucleotides. 98. A convenient and general method for the preparation of protected dideoxyribonucleotides containing 5'-phosphate end groups. (1971) (27)
Studies on polynucleotides: XCVII. Opposing orientations and location of the suIII+ gene in the transducing coliphages φ80psuIII+ and φ80suIII+suIII− (1971) (27)
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4. (2001) (27)
Synthesis of modified fatty acids and glycerophospholipid analogs. (1981) (27)
STUDIES ON POLYNUCLEOTIDES. XXXVII. THE SYNTHESIS OF SPECIFIC DEOXYRIBOPOLYNUCLEOTIDES. FURTHER EXAMINATION OF THE APPROACH INVOLVING STEPWISE SYNTHESIS. (1965) (26)
STUDIES ON POLYNUCLEOTIDES. 33. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE ACETYLATION OF TERMINAL HYDROXYL GROUPS IN DEOXYRIBOPOLYNUCLEOTIDES. (1964) (26)
Hydrogen bonding interactions with the Schiff base of bacteriorhodopsin. Resonance Raman spectroscopy of the mutants D85N and D85A. (1993) (26)
Total synthesis and expression of a gene for the alpha-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin). (1988) (26)
sRNA specificity for codon recognition as studied by the ribosomal binding technique. (1966) (25)
Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin. (1995) (25)
Use of the lipophilic tert-butyldiphenylsilyl protecting group in synthesis and rapid separation of polynucleotides. (1978) (25)
Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1. (2001) (25)
The nucleotide sequence in the promoter region of the fene for an Escherichia coli tyrosine transfer ribonucleic acid. (1975) (25)
Studies on polynucleotides. 73. Synthesis in vitro of polypeptides containing repeating tetrapeptide sequences dependent upon DNA-like polymers containing repeating tetranucleotide sequences: direction of reading of messenger RNA. (1967) (25)
Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region. (1981) (25)
Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit. (1994) (25)
Studies on Polynucleotides. XXXI.1The Specific Synthesis of C3'-C5'-Linked Ribopolynucleotides (6).2A Further Study of the Synthesis of Uridine Polynucleotides3 (1964) (25)
Phosphorylated Sugars. VI.1 Syntheses of α-D-Ribofuranose 1,5-Diphosphate and α-D-Ribofuranose 1-Pyrophosphate 5-Phosphate (1958) (25)
Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin. (2002) (25)
Escherichia coli tyrosine transfer ribonucleic acid genes. Nucleotide sequences of their promoters and of the regions adjoining C-C-A ends. (1976) (25)
Incorporation of fatty acids containing photosensitive groups into phospholipids of Escherichia coli. (1976) (25)
Polynucleotide synthesis and the genetic code. (1966) (25)
Studies on Polynucleotides. LXVI.1 The Synthesis of Deoxyribopolynucleotides Containing Repeating Tetranucleotide Sequences (3). A Further Study of the Synthetic Approach Involving Condensation of Preformed Oligonucleotide Blocks2 (1967) (24)
[94] Preparation of nucleotides and derivatives (1963) (24)
Evidence for Long Range Allosteric Interactions between the Extracellular and Cytoplasmic Parts of Bacteriorhodopsin from the Mutant R82A and Its Second Site Revertant R82A/G231C* (2000) (24)
The nucleotide sequence adjoining the CCA end of an Escherichia coli tyrosine transfer ribonucleic acid gene. (1974) (23)
Incorporation of photosensitive fatty acids into phospholipids of Escherichia coli and irradiation-dependent cross-linking of phospholipids to membrane proteins. (1981) (23)
Phosphorylated Sugars. III. Syntheses of α-D-Ribofuranose 1-Phosphate (1957) (23)
The Labelling of Phosphomonoester End Groups in Amino Acid Acceptor Ribonucleic Acids and its use in the Determination of Nucleotide Sequences (1962) (22)
STUDIES ON POLYNUCLEOTIDES. XLVI. THE SYNTHESIS OF HEXANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCES DEOXYCYCTIDYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE AND DEOXYGUANYLYL-(3'--5')-DEOXYADENYLYL-(3'--5')-DEOXYADENOSINE. (1965) (22)
The preparation of lipid-depleted bacteriorhodopsin. (1977) (22)
Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies. (1999) (22)
STUDIES ON POLYNUCLEOTIDES. 43. THE SYNTHESIS OF DEOXRIBOPOLYNUCLEOTIDES CONTAINING REPEATING DINUCLEOTIDE SEQUENCES. (1965) (22)
Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions. (1995) (22)
Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn. (1992) (22)
Total synthesis of a tyrosine suppressor transfer RNA gene. XVI. Enzymatic joinings to form the total 207-base pair-long DNA. (1979) (21)
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle. (1989) (21)
Studies on Polynucleotides. XXVII.1 The Stepwise Synthesis of Specific Deoxyribopolynucleotides (7).1 The Synthesis of Polynucleotides Containing Deoxycytidine and Deoxyguanosine in Specific Sequences and of Homologous Deoxycytidine Polynucleotides Terminating in Thymidine3 (1963) (21)
Ultraviolet-visible transient spectroscopy of bacteriorhodopsin mutants. Evidence for two forms of tyrosine-185----phenylalanine. (1990) (21)
Studies on Polynucleotides. XXVI.1The Stepwise Synthesis of Specific Deoxyribopolynucleotides (6).2The Synthesis of Thymidylyl-(3″ → 5″)-deoxyadenylyl-(3″ → 5″)-thymidylyl-(3″ → 5″)-thymidylyl-(3″ → 5″)-thymidine and of Polynucleotides Containing Thymidine and Deoxyadenosine in Alternating Sequence3 (1963) (21)
[10] Delipidation, renaturation, and reconstitution of bacteriorhodopsin (1982) (21)
STUDIES ON POLYNUCLEOTIDES. XXXVI. THE SPECIFIC SYNTHESIS OF C3'-C5'-LINKED RIBOOLIGONUCLEOTIDES. IX. THE SYNTHESIS OF RIBODINUCLEOTIDES BEARING 3'-PHOSPHOMONOESTER GROUPS. (1965) (21)
CARBODIIMIDES: PART II. THE REACTION OF SULPHONIC ACIDS WITH CARBODIIMIDES. A NEW METHOD OF PREPARATION OF SULPHONIC ANHYDRIDES (1953) (21)
Nucleoside Polyphosphates. II.1 A Synthesis of Uridine-5'-di- and and -Triphosphate2a (1954) (20)
Deoxyoligonucleotide synthesis using a new phosphate protecting group. (1973) (20)
CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77. (1972) (20)
Studies on polynucleotides. CXX. On the transcription of a synthetic 29-unit long deoxyribopolynucleotide. (1972) (20)
108. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of an undecadeoxynucleotide, a decadeoxynucleotide and an octadeoxynucleotide corresponding to the nucleotide sequences 7 to 27. (1972) (19)
Effect of genetic modification of tyrosine-185 on the proton pump and the blue-to-purple transition in bacteriorhodopsin. (1990) (19)
136. Peptides. Part IV. Selective removal of the C-terminal residue as a thiohydantoin. The use of diphenyl phosphorisothiocyanatidate (1953) (19)
Molecular Biology of Light Transduction by the Mammalian Photoreceptor, Rhodopsin (2000) (19)
Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA. (1972) (19)
Phosphorylated Sugars. I. A Synthesis of β-D-Ribofuranose 1-Phosphate (1956) (19)
SPECIFIC SYNTHESIS OF THE C5'-C3' INTER-RIBONUCLEOTIDE LINKAGE: THE SYNTHESIS OF URIDYLYL-(5' → 3')-URIDINE1,2 (1959) (19)
STUDIES ON POLYNUCLEOTIDES.XLII. THE SYNTHESIS OF DEOXYRIBOPOLYNUCLEOTIDES CONTAINING REPEATING NUCLEOTIDE SEQUENCES. INTRODUCTION AND GENERAL CONSIDERATIONS. (1965) (19)
Studies on Polynucleotides. VII.1Approaches to the Marking of End Groups in Polynucleotide Chains: The Methylation of Phosphomonoester Groups2 (1959) (18)
Studies on Polynucleotides. V.1 Stepwise Synthesis of Oligonucleotides. Syntheses of Thymidylyl-(5' → 3')-thymidylyl-(5' → 3')-thymidine and Deoxycytidylyl-(5' → 3')-deoxyadenylyl-(5' → 3')-thymidine2 (1959) (18)
STUDIES ON POLYNUCLEOTIDES. XXII. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. A. PURIFICATION, PROPERTIES, AND SUBSTRATE SPECIFICITY. (1963) (17)
Optimal strategies for the chemical and enzymatic synthesis of bihelical deoxyribonucleic acids. (1975) (17)
A redirected proton pathway in the bacteriorhodopsin mutant Tyr-57-->Asp. Evidence for proton translocation without Schiff base deprotonation. (1994) (17)
Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. (1972) (17)
Studies of polynucleotides. XCII. The synthesis of a deoxyribododecanucleotide containing specific amino acid codons. (1969) (16)
IDENTIFICATION OF THE LIPID BINDING SITE OF THE PHOSPHATIDYLCHOLINE EXCHANGE PROTEIN WITH A PHOTOSENSITIVE NITRENE AND CARBENE PRECURSOR OF PHOSPHATIDYLCHOLINE (1980) (16)
Nucleoside Polyphosphates. IX.1 The Reversible Formation of Pyrophosphates from Monoesters of Phosphoric Acid by Reaction with Acetic Anhydride2 (1959) (16)
Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes. (1975) (16)
Studies on Polynucleotides. XXI.1 Amino Acid Acceptor Ribonucleic Acids (2). The Labeling of Terminal 5″-Phosphomonoester Groups and a Preliminary Investigation of Adjoining Nucleotide Sequences2 (1963) (16)
Studies on Polynucleotides. LXI.1 Polynucleotide Synthesis in Relation to the Genetic Code. General Introduction2 (1967) (16)
Rhodopsin kinase: expression in baculovirus-infected insect cells, and characterization of post-translational modifications. (1997) (16)
Studies on polynucleotides. 53. Syntheses of trinucleotides containing adenylate and 2'-deoxyadenylate units and a study of their effect on the binding of lysyl soluble ribonucleic acid to ribosomes. (1966) (15)
Phosphorylated Sugars. II. The Preparation of the Anomeric Methyl 5-O-Benzyl-D-ribofuranoside 2,3-Cyclic Carbonates and the Study of their Reactions with Hydrogen Bromide in Acetic Acid (1957) (15)
A new photo-crosslinking reagent for the study of protein-protein interactions (1993) (15)
The structure of lipopolysaccharide from a heptose-less mutant of Escherichia coli K-12. II. The application of 31P NMR spectroscopy. (1979) (15)
Rhodopsin kinase: expression in mammalian cells and a two-step purification. (2000) (15)
Reconstitution of bacteriorhodopsin vesicles with Halobacterium halobium lipids. Effects of variations in lipid composition. (1982) (15)
Photoactivatable carbene-generating phospholipids: physical properties and use in detection of phase separations in lipid mixtures. (1981) (15)
CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex. (1972) (15)
Studies on Polynucleotides LXXVIII. YEAST PHENYLALANINE TRANSFER RIBONUCLEIC ACID: TERMINAL SEQUENCES (1968) (15)
Chemical studies of biological membranes (1980) (14)
SYNTHESIS IN THE STUDY OF NUCLEIC ACIDS (1976) (14)
Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin. (1992) (14)
CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70. (1972) (14)
THE PREPARATION OF NUCLEOSIDE 5'-PHOSPHORAMIDATES AND THE SPECIFIC SYNTHESIS OF NUCLEOTIDE COENZYMES (1957) (14)
Progress in the total synthesis of the gene for ala-tRNA. (1968) (13)
Studies on polynucleotides. 93. A further study of the synthesis of deoxyribopolynucleotides using preformed oligonucleotide blocks. (1969) (13)
A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity. (1992) (13)
The synthesis and cloning of two tyrosine suppressor tRNA genes with altered promoter sequences. (1981) (13)
Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state. (1995) (12)
Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues. (1989) (12)
Thiols and the diazo group in photoaffinity labels. (1980) (12)
Fatty acyl amidases from Dictyostelium discoideum that act on lipopolysaccharide and derivatives. I. Partial purification and properties. (1982) (12)
Synthesis of a new photoactivatable analog of 11-cis-retinal (1990) (12)
A synthetic tyrosine suppressor tRNA gene with an altered promoter sequence. Its cloning and relative expression in vivo. (1979) (12)
Phosphroylated Sugars. IV.1 The Synthesis of D-Xylose 3-Phosphate via 1,2-O-Isopropylidene-D-Xylofuranose-3,5-cyclic Phosphate (1957) (12)
Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. (1992) (12)
Synthesis of phospholipids containing photoactivatable carbene precursors in the headgroups and their crosslinking with membrane proteins. (1985) (12)
Studies on nucleic acids: Total synthesis of a biologically functional gene (1978) (12)
CARBODIIMIDES: PART IV. THE FISSION OF N,N′-DI-p-TOLYL-O-BENZYL AND-O-ALLYL PSEUDOUREA ETHERS IN THE PRESENCE OF ACIDS (1954) (12)
Studies on polynucleotides. CXLIII. A rapid and convenient method for the synthesis of deoxyribooligonucleotides carrying 5'-phosphate end groups using a new protecting group. (1976) (11)
386. Peptides. Part II. Selective degradation by removal of the terminal amino-acid bearing a free amino-group. The use of alkyl alkoxydithioformates (dialkyl xanthates) (1952) (11)
Regeneration of native bacteriorhodopsin structure following acetylation of epsilon-amino groups of Lys-30, -40, and -41. (1986) (11)
STUDIES ON POLYNUCLEOTIDES. XLI. PURIFICATION OF PHENYLALANINE-SPECIFIC TRANSFER RIBONUCLEIC ACID FROM YEAST BY COUNTERCURRENT DISTRIBUTION. (1965) (11)
The Selective Acetylation of Terminal Hydroxyl Groups in Deoxyribo-oligonucleotides (1963) (11)
Nucleoside Polyphosphates. V.1 Syntheses of Guanosine 5'-Di- and Triphosphates (1957) (11)
Sites of photolytic intermolecular crosslinking between fatty acyl chains in phospholipids carrying a photoactivable carbene precursor (1982) (11)
Chemical Biology: Selected Papers of H Gobind Khorana (with Introductions) (2000) (11)
Use of trityl- and -naphthylcarbamoylcellulose derivatives in oligonucleotide synthesis. (1973) (10)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex. (1976) (10)
CIX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a decadeoxynucleotide corresponding to the nucleotide sequence 46 to 65. (1972) (10)
The Tyrosine tRNA Promoter (1976) (10)
Effects of individual genetic substitutions of arginine residues on the deprotonation and reprotonation kinetics of the Schiff base during the bacteriorhodopsin photocycle. (1991) (10)
Total synthesis of a tyrosine suppressor tRNA gene. XVIII. Biological activity and transcription, in vitro, of the cloned gene. (1979) (10)
Structure-function studies on bacteriorhodopsin. I. Expression of the bacterio-opsin gene in Escherichia coli. (1987) (10)
324. The chemistry of bacteria. Part I. The synthesis of hydroxyindoles (1948) (9)
Methods for mutagenesis of the bacterioopsin gene. (1986) (9)
Studies on the light-transducing pigment bacteriorhodopsin. (1983) (9)
A SYNTHESIS OF α-D-RIBOFURANOSE-1-PHOSPHATE (1955) (9)
Fatty acyl amidases from Dictyostelium discoideum that act on lipopolysaccharide and derivatives. II. Aspects of substrate specificity. (1982) (9)
Synthesis and structural analysis of polynucleotides. (1959) (9)
Nucleotide Sequences at the Two Ends of the E. coli Tyrosine tRNA Genes and Studies on the Promoter (1976) (9)
A rapid and efficient procedure for the purification of mitochondrial β-hydroxybutyrate dehydrogenase (1985) (9)
Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin. (2007) (9)
On the heterogeneity of the deoxyribonucleic acid associated with crystalline yeast cytochrome b2. (1965) (9)
Studies on polynucleotides. CXIX. Transcription of short double-stranded deoxyribonucleic acids of defined nucleotide sequences. (1972) (8)
The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation (2011) (8)
A Life in Science (2000) (8)
Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling. (1998) (8)
Study on polynucleotideCXIII. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 17 to 50 (1972) (7)
Rhodopsin kinase: two mAbs binding near the carboxyl terminus cause time-dependent inactivation. (2000) (7)
Guanosine 3',5'-cyclic nucleotide binding proteins of bovine retina identified by photoaffinity labeling. (1990) (7)
The use of tryptophan mutants in identifying the 296 nm transient absorbing species during the photocycle of bacteriorhodopsin (1991) (7)
CVI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of two nonanucleotides and a heptanucleotide corresponding to nucleotide sequences 22 to 30, 41 to 49 and 28 to 34. (1972) (7)
CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77. (1972) (7)
Studies on polynucleotides, XC. DNA polymerase-catalyzed repair of short DNA duplexes with single-stranded ends. (1968) (7)
Too Many Chemistry Journals (1974) (6)
D-XYLOSE-3-PHOSPHATE (1956) (6)
Light‐induced currents in Xenopus oocytes expressing bovine rhodopsin. (1993) (6)
Incorporation of Synthetic Fatty Acid Analogs into Phospholipids of Escherichia coli (1979) (6)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 12. Synthesis of a DNA duplex corresponding to a sequence of 23 nucleotide units adjoining the C-C-A end. (1976) (6)
The nucleotide sequence in the promoter region of the gene N in bacteriophage lambda. (1975) (6)
Interaction of cholesterol with photoactivable phospholipids in sonicated vesicles. (1981) (6)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103. (1976) (6)
STUDIES ON POLYNUCLEOTIDES. 23. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. B. STEPWISE DEGRADATION OF OLIGONUCLEOTIDES. (1963) (6)
A New Method for the Labelling of 5′-Phosphomonoester End Groups in Amino Acid Acceptor Ribonucleic Acids (1963) (6)
Introduction and characterization of amber mutations in the bacteriorhodopsin gene. (1983) (6)
Total synthesis of a tyrosine suppressor transfer RNA gene. XIV. Chemical synthesis of oligonucleotide segments corresponding to the terminal regions. (1979) (5)
Rhodopsin, the Visual Pigment, and Bacteriorhodopsin a (1986) (5)
Structure and Mechanism in G Protein-coupled Receptors (2002) (5)
Specificity of sRNA for Recognition of Codons as Studied by the Ribosomal Binding Technique (1989) (5)
Effects of tryptophan mutation on the deprotonation and reprotonation kinetics of the Schiff base during the photocycle of bacteriorhodopsin. (1992) (5)
186. The chemistry of bacteria. Part II. Some degradation products of violacein (1949) (5)
CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40. (1972) (5)
Studies on light transduction by bacteriorhodopsin and rhodopsin. (1988) (5)
Studies on polynucleotides. LXX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating tetranucleotide sequences. (1967) (5)
Total synthesis of a tyrosine suppressor tRNA gene. XV. Synthesis of the promoter region. (1979) (5)
Studies on polynucleotides. X. Enzymic degradation. Some properties and mode of action of spleen phosphodiesterase. (1961) (5)
Total synthesis of a gene (2012) (5)
Structural investigation of peptides and proteins (1952) (5)
Missense suppression in tryptophan synthetase. (1966) (4)
The Synthesis of Deoxyribo-Polynucleotides Containing Specific Nucleotide Sequences (1963) (4)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126. (1976) (4)
The Stepwise Synthesis of Ribo-Oligonucleotides Containing C3″-C5″ Internucleotidic Linkages (1963) (4)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126. (1976) (4)
An alternative method of preparing radiolabeled photoactivatable fatty acids. (1981) (4)
CHAPTER 31 – Chemical and Enzymic Synthesis of Polynucleotides (1960) (4)
A new approach to the specific synthesis of the C3'-C5' inter-ribonucleotide linkage. (1962) (4)
Bioenergetics: Bacteriorhodopsin, a Light-Driven Proton Pump (2000) (4)
Total synthesis of a tyrosine suppressor transfer RNA gene. XIII. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence -1 to -29 in the promoter region. (1979) (3)
The synthesis of a DNA duplex corresponding to the icosanucleotide sequence at the 5' end of messenger RNA from the gene N of bacteriophage lambda. (1975) (3)
Cloning of Two Chemically Synthesized Genes for a Precursor to the su + 3 Suppressor tRNA Tyr (1980) (3)
STUDIES ON POLYNUCLEOTIDES. CXLIII. A RAPID AND CONVENIENT METHOD FOR THE SYNTHESIS OF DEOXYRIBOOLIGONUCLEOTIDES CARRYING 5′-PHOSPHATE END GROUPS USING A NEW PROTECTING GROUP (1976) (3)
Studies on polynucleotides. 118. A further study of ribonucleotide incorporation into deoxyribonucleic acid chains by deoxyribonucleic acid polymerase I of Escherichia coli. (1972) (3)
Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: Expression of 15 N-lysine- and 13 C-glycine-labeled opsin in a stable cell line (HEK293S cellsyG protein-coupled receptorysignal transductiony11-cis retinalyvisual pigment) (1999) (3)
Synthetic nucleic acids and the genetic code. (1968) (2)
Development of the Chemistry and Macromolecular Structures of Nucleic Acids (2000) (2)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 7. Enzymatic joining of the chemically synthesized segments to form a DNA duplex corresponding to the nucleotide sequence 1-26. (1976) (2)
TOTAL SYNTHESIS OF A BACTERIAL GENE II: THE TOTAL DNA INCLUDING THE PROMOTER AND ITS TRANSCRIPTION (1978) (2)
Studies on polynucleotides. XV. Enzymic degradation. The mode of action of pancreatic deoxyribonuclease on thymidine, deoxycytidine, and deoxyadenosine polynucleotides. (1962) (2)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 9. Enzymatic joining of chemically synthesized deoxyribopolynucleotide segments corresponding to nucleotide sequence 57-94. (1976) (2)
Studies on DNA Polymerases II and III of Escherichia coli (1973) (2)
A rapid and efficient procedure for the purification of mitochondrial beta-hydroxybutyrate dehydrogenase. (1985) (2)
cDNA-derived amino acid sequence of the y subunit of GTPase from bovine rod outer segments ( rhodopsin / cyclic GMP phosphodiesterase / adenylate cyclase / hybrid-selected mRNA / expression vector (2)
THE SYNTHESIS OF GUANOSINE-5'-PHOSPHATE USING A NEW METHOD OF PHOSPHORYLATION (1955) (2)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 3. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 27-51. (1976) (1)
NEUTRON ACTIVATION AS A METHOD FOR LABELLING THE PHOSPHORUS OF NUCLEOTIDES (1963) (1)
113. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 17 to 50. (1972) (1)
The specific synthesis of C3,-C5,-linked uridine oligonucleotides. (1962) (1)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78. (1976) (1)
The nucleotide sequence in the promoter region of the gene for an Escherichia coli tyrosine transfer ribonucleic acid. (1976) (1)
Recent work on bacteriorhodopsin. (1987) (1)
STUDIES ON POLYNUCLEOTIDES. XLV. THE SYNTHESIS OF DODECANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCE THYMIDYLYL-(3'--5')-THYMIDYLYL-(3'--5')-DEOXYINOSINE. (1965) (1)
Activation mechanism of G protein-coupled receptors : Construction of light-activated β₂-adrenergic receptor (2004) (1)
Preparation of a circular bihelical deoxyribonucleic acid containing repeating dinucleotide sequences. (1971) (1)
STUDIES ON POLYNUCLEOTIDES. XXXII. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE PHOSPHORYLATION OF PHOSPHOMONOESTER GROUPS IN AMINO ACID ACCEPTOR RIBONUCLEIC ACIDS. (1964) (1)
Gene Amplification (PCR) (2000) (1)
Transfer RNA: Discovery, Early Work, and Total Synthesis of a tRNA Gene (1995) (1)
A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends. 1972. (1992) (1)
Mutagenesis Studies of Rhodopsin Phototransduction (1992) (1)
High-Level Expression , Single-Step Immunoaffinity Purification and Characterization of Human Tetraspanin Membrane Protein CD 81 (2008) (1)
Synthesis of nucleotides, nucleotide coenzymes and polynucleotides. (1960) (1)
Letter from H. Gobind Khorana to Francis Crick (1965) (1)
13 – Expression and Site-Specific Mutagenesis of an Integral Membrane Protein, Bacterio-Opsin (1973) (1)
Development of the Chemistry and Macromolecular Structures of Proteins (2000) (1)
The Synthesis of Transfer RNA Genes (1972) (0)
Phosphoric Acid Esters in Intermediary Metabolism: Development of Methods for Their Synthesis (2000) (0)
THE YEAR 1948-1949 IN PRELOG LABORATORY AT E.T.H., ZURICH : A REMINISCENCE (1996) (0)
FROM CARBODIIMIDE TO GENE SYNTHESIS1 (1981) (0)
Incorporation of fatty acids contaii phospholipids of Escherichia coli (membranes/crosslinking/proteins/unsaturated fatty acids auxol (2016) (0)
Structure and function in rhodopsin: Topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops* (G protein-coupled receptorysignal transductionydisulfide crosslinkingysite-directed spin labelingyconformational change) (1997) (0)
The Genetic Code (B): Basic Features and Codon Assignments (2000) (0)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 8. Enzymatic joining of the chemically synthesized segments to form DNA duplexes corresponding to nucleotide sequences 23-60 and 23-66. (1976) (0)
A Reminiscence (2004) (0)
Rapid separation of synthetic oligonucleotide mixtures on aromatic cellulose derivatives. (1974) (0)
The Total Synthesis of Genes (2000) (0)
STRUCTURE-FUNCTION STUDIES OF BOVINE RHODOPSIN: INTERACTIONS WITH TRANSDUCIN' (2003) (0)
STUDIES ON POLYNUCLEOTIDES , LXXXVIII (0)
Carbodiimides as Synthetic Reagents (2000) (0)
Total synthesis of transfer RNA genes. (1974) (0)
Polynucleotide synthesis and the genetic code. (1965) (0)
Too many chemistry journals [1] (1973) (0)
Structure and function in rhodopsin : The fate of opsin formed upon the decay of light-activated metarhodopsin II in vitro ( opsin unfolding / folding / denaturation / 11-is-retinal / chromophore / regeneration ) (2005) (0)
Molecular and Biological Studies on Visual Processes (Studies on Vision). (1984) (0)
Amino Acid Substitutions in Bacteriorhodopsin 9279 (2001) (0)
8 – Design and Total Chemical Synthesis of a Gene for Bovine Rhodopsin (1973) (0)
Studies on polynucleotides. 78. Yeast phenylalanine transfer ribonucleic acid: terminal sequences. (1968) (0)
Signal transduction in two light-transducing systems: bacteriorhodopsin and mammalian rhodopsin. (1993) (0)
OPTIMAL STRATEGIES FOR THE CHEMICAL AND ENZYMATIC SYNTHESIS OF BIHELICAL DEOXYRIBONUCLEIC ACIDS (1975) (0)
DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE POLYMERS CONTAINING REPEATING NUCLEOTIDE (0)
Svnthesis of Deoxvribopolynucleotides Containing Repeating Di-and Trinucleotide Sequence (1998) (0)
Structure and function in rhodopsin: The role of asparagine-linked glycosylation (membrane protein/signal transduction/carbohydrate/structure-function relationship) (2016) (0)
[The purification and the characterization of an exonuclease of Lactobacillus acidophilus R 26]. (1963) (0)
CXXIT. THE DODECRNUCLEOTIDE SEQUEKCE ADJOIMSG THE C-C-A END OF THE TYROSINE TRANSFER RIBOKUCLEIC ACID GENE* (2006) (0)
SITE-SPECIFIC MUTAGENESIS OF BOVINE RHODOPSIN1 (2003) (0)
STUDIES ON POLYNUCLEOTIDES. XL. SYNTHETIC DEOXYRIBOPOLYNUCLEOTIDES AS TEMPLATES FOR RIBONUCLEIC ACID POLYMERASE: THE INFLUENCE OF TEMPERATURE ON TEMPLATE FUNCTION. (1965) (0)
Structure and function in rhodopsin : Topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops * ( G protein-coupled receptor y signal transduction y disulfide crosslinking y site-directed spin labeling y conformational change ) (1997) (0)
TOTAL SYNTHESIS OF A BACTERIAL GENE I: CHEMICAL SYNTHESIS OF OLIGONUCLEOTIDES AND USE OF HIGH-PRESSURE LIQUID CHROMATOGRAPHY (1978) (0)
The effects of replacing loop residues with structure-less linkers upon folding of bacteriorhodopsin (2000) (0)
Studies on polynucleotides. LV. The use of mesitoyl chloride in the synthesis of internucleotide bonds. (1966) (0)
Structure and function in rhodopsin : Covalent crosslinking of the rhodopsin ( metarhodopsin II )-transducin complex-the rhodopsin cytoplasmic face links to the transducin a subunit ( signal transduction / site-specific mutageness / GTP-binding protein / photoactivatable group / phenyidazlrine ) (0)
Studies on polynucleotides, lxxxiv. On the role of ribosomal subunits in protein synthesis. (1968) (0)
11. A Single Amino Acid Substitution in Rhodopsin (Lysine 248–>Leucine) Prevents Activation of Transducin | PMID: 3123487 (2001) (0)
Letter from H. Gobind Khorana to Joshua Lederberg (1970) (0)
OF RIBOSE 5-PHOSPHATE IN THE ENZYMATIC SYNTHESIS OF 5-PHOSPHORYLRIBOSE I-PYROPHOSPHATE * (1957) (0)
(purple membrane/proton pump/oligonucleotide purification/site-sp4 (2016) (0)
STUDIES ON POLYNUCLEOTIDES, LXXXVIH.* THE JOINING OF SHORT DEOXYRIBOPOLYNUCLEOTIDES BY DNA-JOINING ENZYMESt (0)
Studies on polynucleotides. CXXII. The dodecanucleotide sequence adjoining the C-C-A end of the tyrosine transfer ribonucleic acid gene. (1973) (0)
STUDIES ON POLYNUCLEOTIDES, LXXXVIII.* ENZYMATIC JOINING OF CHEMICALLY SYNTHESIZED SEGMENTS CORRESPONDING TO THE GENE FOR ALANINE-tRNAt (0)
A STUDY ON INTERMEDIATE N USING BACTERIORHODOPSIN ASP-96 MUTANTS (1992) (0)
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 2. Chemical synthesis of the deoxypolynucleotide segments corresponding to the nucleotide sequence 1-31. (1976) (0)
CVII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a hexadeoxynucleotide corresponding to the nucleotide sequence 1 to 12. (1972) (0)
Studies on Polynueleotides (2003) (0)
Metarhodopsin II State 187 , Components of a Conserved Disulfide Bond in Rhodopsin , Affects the Light-Activated Structure and Function in Rhodopsin : Replacement by Alanine of Cysteine Residues (0)
Structure and function in rhodop binding to purified opsin mutant, detergent mixtures serve as prob (G-protein-coupled receptors/signal transduction/11-cis-retinal/ (2016) (0)
Research programs in Japan. (1998) (0)
STUDIES ON POLYNUCLEOTIDES. XXXV. THE SPECIFIC SYNTHESIS OF C3'-C5'-LINKED RIBOOLIGONUCLEOTIDES. 8. THE SYNTHESIS OF RIBODINUCLEOTIDES BEARING 3'-PHOSPHOMONOESTER GROUPS. (1965) (0)
EFFECTS OF ARG-82 GLN AND ARG-227 GLN SUBSTITUTIONS ON BACTERIORHODOPSINFUNCTION (1992) (0)
STUDIES ON POLYNUCLEOTIDES. XLIV. THE SYNTHESIS OF DODECANUCLEOTIDES CONTAINING THE REPEATING TRINUCLEOTIDE SEQUENCE THYMIDYLYL-(3'--5')-THYMIDYLYL-(3'--5')-DEOXYCYTIDINE. (1965) (0)
Studies on polynucleotides. XCVII. Opposing orientations and location of the su+3 gene in the transducing coliphages phi-80psu+3 and phi-80dsu+3su-3. (1971) (0)
Studies on polynucleotides. LIV. A further study of the reaction of nucleotide pyrophosphates with carboxylic acid anhydrides. (1966) (0)
Proceedings: Controlled transcription of the synthetic gene for tyrosine transfer RNA. (1976) (0)
Expression and Purification of Rhodopsin and Its Mutants from Stable Mammalian Cell Lines for NMR Studies (1999) (0)
Synthesis of Ribodinucleotides with Terminal 3′‐Phosphate Groups (1964) (0)
Enzymes That Degrade Nucleic Acids (2000) (0)
Amino Acid Sequence of the Membranous Segment of Rabbit Liver Cytochrome b 5 (2001) (0)
THE STRUCTURE AND SYNTHESIS OF A TYROSINE TRANSFER RNA GENE (1974) (0)
Gene Synthesis with H G Khorana (2012) (0)
The Genetic Code (A): Specificity in Protein Synthesis; the Transfer Ribonucleic Acids (2000) (0)
Nucleotide Sequence inthePromoterRegionoftheEscherichia coli Tyrosine tRNAGene (1974) (0)
The conformations of rhodopsin, activated rhodopsin and opsin in detergent micelles and phospholipid bilayers (2003) (0)

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