Harry L.T. Mobley
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American microbiologist and immunologist
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Why Is Harry L.T. Mobley Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Mobley received his Ph.D. at the University of Louisville School of Medicine and conducted postdoctoral work at the University of Maryland School of Medicine in Biochemistry and Vaccine Development, after which he joined the faculty in the Division of Infectious Diseases and rose to the rank of Professor of Microbiology and Immunology. After 23 years at Maryland, Dr. Mobley was named Chair of the Department of Microbiology and Immunology at the University of Michigan Medical School in 2004, serving in this role until 2019. Dr. Mobley’s research focuses on uropathogenic E. coli and Proteus mirabilis, but has also studied Helicobacter pylori and Gram-negative bacterial species causing bacteremia including E. coli, Klebsiella pneumoniae, Acinetobacter baumannii, Citrobacter freundii, and Serratia marcescens.
Harry L.T. Mobley's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Pathogenic Escherichia coli (2004) (4594)
- Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli (2002) (1482)
- Molecular biology of microbial ureases. (1995) (1124)
- Microbial ureases: significance, regulation, and molecular characterization. (1989) (1073)
- Complicated Catheter-Associated Urinary Tract Infections Due to Escherichia coli and Proteus mirabilis (2008) (726)
- Pyelonephritogenic Escherichia coli and killing of cultured human renal proximal tubular epithelial cells: role of hemolysin in some strains (1990) (524)
- Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival (2001) (403)
- Host–pathogen interactions in urinary tract infection (2010) (395)
- Transcriptome of Uropathogenic Escherichia coli during Urinary Tract Infection (2004) (367)
- Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract (2007) (365)
- Urease-positive bacteriuria and obstruction of long-term urinary catheters (1987) (315)
- Urinary tract infections : molecular pathogenesis and clinical management (1996) (315)
- Characterization of urease from Campylobacter pylori (1988) (296)
- Vaxign: The First Web-Based Vaccine Design Program for Reverse Vaccinology and Applications for Vaccine Development (2010) (270)
- Fitness of Escherichia coli during Urinary Tract Infection Requires Gluconeogenesis and the TCA Cycle (2009) (258)
- Purification and N-terminal analysis of urease from Helicobacter pylori (1990) (257)
- Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine production. (1996) (250)
- Role of P-fimbrial-mediated adherence in pyelonephritis and persistence of uropathogenic Escherichia coli (UPEC) in the mammalian kidney. (2007) (245)
- Defining Genomic Islands and Uropathogen-Specific Genes in Uropathogenic Escherichia coli (2007) (238)
- Merging mythology and morphology: the multifaceted lifestyle of Proteus mirabilis (2012) (238)
- Complete Genome Sequence of Uropathogenic Proteus mirabilis, a Master of both Adherence and Motility (2008) (232)
- Helicobacter pylori urease activity is toxic to human gastric epithelial cells (1990) (232)
- Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury. (2015) (230)
- Synthesis and activity of Helicobacter pylori urease and catalase at low pH. (1997) (226)
- Waging War against Uropathogenic Escherichia coli: Winning Back the Urinary Tract (2009) (211)
- Role of Motility in the Colonization of Uropathogenic Escherichia coli in the Urinary Tract (2005) (210)
- Redundancy and Specificity of Escherichia coli Iron Acquisition Systems during Urinary Tract Infection (2011) (208)
- Identification of Sat, an autotransporter toxin produced by uropathogenic Escherichia coli (2000) (208)
- Sat, the Secreted Autotransporter Toxin of Uropathogenic Escherichia coli, Is a Vacuolating Cytotoxin for Bladder and Kidney Epithelial Cells (2002) (202)
- Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. (1996) (200)
- Swarming and pathogenicity of Proteus mirabilis in the urinary tract. (1995) (197)
- Escherichia coli Global Gene Expression in Urine from Women with Urinary Tract Infection (2010) (197)
- Proteus mirabilis Genes That Contribute to Pathogenesis of Urinary Tract Infection: Identification of 25 Signature-Tagged Mutants Attenuated at Least 100-Fold (2004) (196)
- Pathogenesis of Proteus mirabilis urinary tract infection. (2000) (188)
- Construction of a urease-negative mutant of Proteus mirabilis: analysis of virulence in a mouse model of ascending urinary tract infection (1990) (173)
- Isogenic P‐fimbrial deletion mutants of pyelonephritogenic Escherichia coli: the role of α Gal(1–4)β Gal binding in virulence of a wild‐type strain (1993) (167)
- Mucosal Immunization with Iron Receptor Antigens Protects against Urinary Tract Infection (2009) (167)
- Genomic Analysis of a Pathogenicity Island in Uropathogenic Escherichia coli CFT073: Distribution of Homologous Sequences among Isolates from Patients with Pyelonephritis, Cystitis, and CatheterAssociated Bacteriuria and from Fecal Samples (1998) (166)
- Preventing urinary tract infection: progress toward an effective Escherichia coli vaccine (2012) (165)
- Coordinate Expression of Fimbriae in Uropathogenic Escherichia coli (2005) (165)
- Helicobacter pylori nickel‐transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditions (1995) (165)
- Microbial ureases: significance, regulation, and molecular characterization (1989) (162)
- Host-specific induction of Escherichia coli fitness genes during human urinary tract infection (2014) (161)
- Escherichia coli Isolates That Carry vat, fyuA, chuA, and yfcV Efficiently Colonize the Urinary Tract (2012) (158)
- Pathogenesis of Proteus mirabilis Infection. (2018) (157)
- Virulence and Fitness Determinants of Uropathogenic Escherichia coli. (2015) (156)
- Uropathogenic Escherichia coli Outer Membrane Antigens Expressed during Urinary Tract Infection (2007) (155)
- Genetic and biochemical diversity of ureases of Proteus, Providencia, and Morganella species isolated from urinary tract infection (1987) (147)
- Contribution of Proteus mirabilis urease to persistence, urolithiasis, and acute pyelonephritis in a mouse model of ascending urinary tract infection (1993) (146)
- Helicobacter pylori urease: properties and role in pathogenesis. (1991) (141)
- Pathogenicity island sequences of pyelonephritogenic Escherichia coli CFT073 are associated with virulent uropathogenic strains (1997) (141)
- Genome-Wide Identification of Klebsiella pneumoniae Fitness Genes during Lung Infection (2015) (135)
- Construction of a flagellum-negative mutant of Proteus mirabilis: effect on internalization by human renal epithelial cells and virulence in a mouse model of ascending urinary tract infection (1996) (134)
- Quantitative Profile of the Uropathogenic Escherichia coli Outer Membrane Proteome during Growth in Human Urine (2007) (133)
- Mechanisms of Helicobacter pylori infection: bacterial factors. (1999) (132)
- Proteus mirabilis urease: nucleotide sequence determination and comparison with jack bean urease (1989) (131)
- Genomic Islands of Uropathogenic Escherichia coli Contribute to Virulence (2009) (130)
- Use of polymerase chain reaction-amplified Helicobacter pylori urease structural genes for differentiation of isolates (1992) (129)
- Detection of Helicobacter pylori by using the polymerase chain reaction (1991) (126)
- Escherichia coli physiology and metabolism dictates adaptation to diverse host microenvironments. (2012) (126)
- Assessment of Virulence of Uropathogenic Escherichia coli Type 1 Fimbrial Mutants in Which the Invertible Element Is Phase-Locked On or Off (2002) (125)
- Fimbrial Profiles Predict Virulence of Uropathogenic Escherichia coli Strains: Contribution of Ygi and Yad Fimbriae (2011) (125)
- Molecular biology of microbial ureases (1995) (123)
- Proteus mirabilis urease: genetic organization, regulation, and expression of structural genes (1988) (121)
- Complex Interplay between Type 1 Fimbrial Expression and Flagellum-Mediated Motility of Uropathogenic Escherichia coli (2007) (118)
- The Innate Immune Response to Uropathogenic Escherichia coli Involves IL-17A in a Murine Model of Urinary Tract Infection (2010) (117)
- Genome-Wide Detection of Fitness Genes in Uropathogenic Escherichia coli during Systemic Infection (2013) (115)
- In Vivo Dynamics of Type 1 Fimbria Regulation in UropathogenicEscherichia coli during Experimental Urinary Tract Infection (2001) (115)
- Helicobacter pylori rocF Is Required for Arginase Activity and Acid Protection In Vitro but Is Not Essential for Colonization of Mice or for Urease Activity (1999) (115)
- Haem acquisition is facilitated by a novel receptor Hma and required by uropathogenic Escherichia coli for kidney infection (2009) (115)
- Energetics of plasmid-mediated arsenate resistance in Escherichia coli. (1982) (112)
- The IrgA Homologue Adhesin Iha Is an Escherichia coli Virulence Factor in Murine Urinary Tract Infection (2005) (110)
- Uropathogenic Escherichia coli. (2009) (107)
- Autotransporter Genes pic and tsh Are Associated with Escherichia coli Strains That Cause Acute Pyelonephritis and Are Expressed during Urinary Tract Infection (2004) (106)
- Helicobacter pylori Growth and Urease Detection in the Chemically Defined Medium Ham's F-12 Nutrient Mixture (2001) (105)
- Multicellular Bacteria Deploy the Type VI Secretion System to Preemptively Strike Neighboring Cells (2013) (104)
- Insertion and fate of the cell wall in Bacillus subtilis (1984) (104)
- The use of a DNA probe for epidemiological studies of candidiasis in immunocompromised hosts. (1989) (102)
- Emergence of resistance to imipenem in Pseudomonas aeruginosa (1987) (101)
- Cytotoxicity of the HpmA hemolysin and urease of Proteus mirabilis and Proteus vulgaris against cultured human renal proximal tubular epithelial cells (1991) (100)
- Physiology and Molecular Biology (2001) (100)
- Defining Helicobacter pylori as a pathogen: strain heterogeneity and virulence. (1996) (97)
- Hemagglutinin, urease, and hemolysin production by Proteus mirabilis from clinical sources. (1990) (97)
- Construction of an MR/P fimbrial mutant of Proteus mirabilis: role in virulence in a mouse model of ascending urinary tract infection (1994) (95)
- Virulence determinants of uropathogenic Escherichia coli and Proteus mirabilis. (1994) (95)
- Helicobacter pylori factors associated with disease development. (1997) (94)
- Visualization of Proteus mirabilis within the Matrix of Urease-Induced Bladder Stones during Experimental Urinary Tract Infection (2002) (94)
- Immunization with the Yersiniabactin Receptor, FyuA, Protects against Pyelonephritis in a Murine Model of Urinary Tract Infection (2013) (93)
- Repression of bacterial motility by a novel fimbrial gene product (2001) (92)
- Isolation of Helicobacter pylori Genes That Modulate Urease Activity (1999) (92)
- Purification of recombinant Helicobacter pylori urease apoenzyme encoded by ureA and ureB (1992) (88)
- In vivo phase variation of MR/P fimbrial gene expression in Proteus mirabilis infecting the urinary tract (1997) (88)
- FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections (2012) (87)
- Transcriptome of Swarming Proteus mirabilis (2010) (86)
- Role of the K2 capsule in Escherichia coli urinary tract infection and serum resistance. (2008) (84)
- VO: Vaccine Ontology (2009) (84)
- Dissemination and Systemic Colonization of Uropathogenic Escherichia coli in a Murine Model of Bacteremia (2010) (82)
- Proteus mirabilis flagella and MR/P fimbriae: isolation, purification, N-terminal analysis, and serum antibody response following experimental urinary tract infection (1991) (81)
- Expression of type 1 fimbriae may be required for persistence of Escherichia coli in the catheterized urinary tract (1987) (81)
- Proteus mirabilis MR/P fimbrial operon: genetic organization, nucleotide sequence, and conditions for expression (1994) (81)
- Helicobacter pylori Containing Only Cytoplasmic Urease Is Susceptible to Acid (1998) (81)
- Preferential Use of Central Metabolism In Vivo Reveals a Nutritional Basis for Polymicrobial Infection (2015) (80)
- Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes, fitness factors for catheter-associated urinary tract infection, and the impact of polymicrobial infection on fitness requirements (2017) (79)
- Increased incidence of urolithiasis and bacteremia during Proteus mirabilis and Providencia stuartii coinfection due to synergistic induction of urease activity. (2014) (79)
- Development of an Intranasal Vaccine To Prevent Urinary Tract Infection by Proteus mirabilis (2004) (78)
- A novel autotransporter of uropathogenic Proteus mirabilis is both a cytotoxin and an agglutinin (2008) (78)
- Role of Phase Variation of Type 1 Fimbriae in a Uropathogenic Escherichia coli Cystitis Isolate during Urinary Tract Infection (2006) (78)
- Host Characteristics and Bacterial Traits Predict Experimental Virulence for Escherichia coli Bloodstream Isolates From Patients With Urosepsis (2015) (78)
- In vivo phase variation of Escherichia coli type 1 fimbrial genes in women with urinary tract infection. (1999) (78)
- MR/K hemagglutination of Providencia stuartii correlates with adherence to catheters and with persistence in catheter-associated bacteriuria. (1988) (77)
- Identification of protease and rpoN-associated genes of uropathogenic Proteus mirabilis by negative selection in a mouse model of ascending urinary tract infection. (1999) (77)
- Visualization of Proteus mirabilis Morphotypes in the Urinary Tract: the Elongated Swarmer Cell Is Rarely Observed in Ascending Urinary Tract Infection (2003) (77)
- Proteus mirabilis urease: transcriptional regulation by UreR (1993) (76)
- Products of enteropathogenic Escherichia coli inhibit lymphocyte activation and lymphokine production (1995) (76)
- Rapid Growth of Uropathogenic Escherichia coli during Human Urinary Tract Infection (2018) (75)
- Uropathogenicity in rats and mice of Providencia stuartii from long-term catheterized patients. (1987) (75)
- In Vivo Behavior of a Helicobacter pylori SS1 nixA Mutant with Reduced Urease Activity (2002) (75)
- Mannose-Resistant Proteus-Like Fimbriae Are Produced by Most Proteus mirabilis Strains Infecting the Urinary Tract, Dictate the In Vivo Localization of Bacteria, and Contribute to Biofilm Formation (2004) (74)
- Isogenic P-fimbrial deletion mutants of pyelonephritogenic Escherichia coli: the role of alpha Gal(1-4) beta Gal binding in virulence of a wild-type strain. (1993) (74)
- PapX, a P Fimbrial Operon-Encoded Inhibitor of Motility in Uropathogenic Escherichia coli (2008) (73)
- The Pathogenic Potential of Proteus mirabilis Is Enhanced by Other Uropathogens during Polymicrobial Urinary Tract Infection (2016) (72)
- Conserved Residues and Motifs in the NixA Protein ofHelicobacter pylori Are Critical for the High Affinity Transport of Nickel Ions* (1998) (72)
- Identification of uropathogenic Escherichia coli surface proteins by shotgun proteomics. (2009) (71)
- Proteus mirabilis fimbriae: construction of an isogenic pmfA mutant and analysis of virulence in a CBA mouse model of ascending urinary tract infection (1994) (71)
- Nutritional Requirements and Antibiotic Resistance Patterns of Helicobacter Species in Chemically Defined Media (2006) (70)
- Multiple Genes Repress Motility in Uropathogenic Escherichia coli Constitutively Expressing Type 1 Fimbriae (2008) (69)
- Identification of MrpI as the sole recombinase that regulates the phase variation of MR/P fimbria, a bladder colonization factor of uropathogenic Proteus mirabilis (2002) (68)
- Expression of catalytically active recombinant Helicobacter pylori urease at wild-type levels in Escherichia coli (1993) (68)
- Cloning of urease gene sequences from Providencia stuartii (1986) (67)
- Proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad (1995) (66)
- Helicobacter pylori ABC transporter: effect of allelic exchange mutagenesis on urease activity (1997) (66)
- The Versatile Type VI Secretion System. (2016) (65)
- Transcriptome of Proteus mirabilis in the Murine Urinary Tract: Virulence and Nitrogen Assimilation Gene Expression (2011) (65)
- Requirement of MrpH for Mannose-ResistantProteus-Like Fimbria-Mediated Hemagglutination byProteus mirabilis (1999) (65)
- Protease Activity, Secretion, Cell Entry, Cytotoxicity, and Cellular Targets of Secreted Autotransporter Toxin of Uropathogenic Escherichia coli (2006) (65)
- Helicobacter pylori protocols (1997) (65)
- Internalization of Proteus mirabilis by human renal epithelial cells (1994) (64)
- Siderophore vaccine conjugates protect against uropathogenic Escherichia coli urinary tract infection (2016) (63)
- Back to the metal age: battle for metals at the host-pathogen interface during urinary tract infection. (2015) (62)
- Proteus mirabilis fimbriae: identification, isolation, and characterization of a new ambient-temperature fimbria (1994) (62)
- The broadly conserved regulator PhoP links pathogen virulence and membrane potential in Escherichia coli (2011) (61)
- Role of Hpn and NixA of Helicobacter pylori in Susceptibility and Resistance to Bismuth and Other Metal Ions (1999) (61)
- Separate resistances to arsenate and arsenite (antimonate) encoded by the arsenical resistance operon of R factor R773 (1985) (60)
- Identification of virulence determinants in uropathogenic Proteus mirabilis using signature-tagged mutagenesis. (2008) (59)
- Zinc Uptake Contributes to Motility and Provides a Competitive Advantage to Proteus mirabilis during Experimental Urinary Tract Infection (2010) (59)
- Dietary L-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut (2019) (58)
- Initiation of Swarming Motility by Proteus mirabilis Occurs in Response to Specific Cues Present in Urine and Requires Excess l-Glutamine (2013) (57)
- Identification of DNA sequences from a second pathogenicity island of uropathogenic Escherichia coli CFT073: probes specific for uropathogenic populations. (2001) (57)
- Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli. (1994) (56)
- Vaccination with Proteus Toxic Agglutinin, a Hemolysin-Independent Cytotoxin In Vivo, Protects against Proteus mirabilis Urinary Tract Infection (2008) (55)
- Metabolism and Fitness of Urinary Tract Pathogens. (2015) (54)
- Enzymatically Active and Inactive Phosphodiesterases and Diguanylate Cyclases Are Involved in Regulation of Motility or Sessility in Escherichia coli CFT073 (2012) (54)
- Acinetobacter baumannii Genes Required for Bacterial Survival during Bloodstream Infection (2015) (54)
- Proteobactin and a yersiniabactin‐related siderophore mediate iron acquisition in Proteus mirabilis (2010) (53)
- SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains (2014) (52)
- Acinetobacter baumannii Is Dependent on the Type II Secretion System and Its Substrate LipA for Lipid Utilization and In Vivo Fitness (2015) (52)
- Lipocalin 2 Imparts Selective Pressure on Bacterial Growth in the Bladder and Is Elevated in Women with Urinary Tract Infection (2014) (52)
- Oxygen-Limiting Conditions Enrich for Fimbriate Cells of Uropathogenic Proteus mirabilis and Escherichia coli (2008) (51)
- Identification of In Vivo-Induced Antigens Including an RTX Family Exoprotein Required for Uropathogenic Escherichia coli Virulence (2011) (51)
- The coupling of wall growth and chromosome replication in Gram-positive rods (1981) (51)
- Membrane Topology of the NixA Nickel Transporter ofHelicobacter pylori: Two Nickel Transport-Specific Motifs within Transmembrane Helices II and III (2000) (51)
- Capsule Production and Glucose Metabolism Dictate Fitness during Serratia marcescens Bacteremia (2017) (51)
- Colonization of mucosal surfaces. (2005) (50)
- Morganella morganii urease: purification, characterization, and isolation of gene sequences (1990) (50)
- Pathogenic Escherichia coli. (2005) (50)
- Repression of motility during fimbrial expression: identification of 14 mrpJ gene paralogues in Proteus mirabilis (2008) (48)
- How Often Do Clinically Diagnosed Catheter‐Associated Urinary Tract Infections in Nursing Homes Meet Standardized Criteria? (2017) (48)
- Development of a Vaccine against Escherichia coli Urinary Tract Infections (2015) (47)
- Vaccines for Proteus mirabilis in urinary tract infection. (2002) (47)
- Proteus mirabilis urease: operon fusion and linker insertion analysis of ure gene organization, regulation, and function (1995) (47)
- Presence of Putative Repeat-in-Toxin Gene tosA in Escherichia coli Predicts Successful Colonization of the Urinary Tract (2011) (46)
- The type III secretion system of Proteus mirabilis HI4320 does not contribute to virulence in the mouse model of ascending urinary tract infection. (2007) (46)
- Helicobacter pylori HP1512 Is a Nickel-Responsive NikR-Regulated Outer Membrane Protein (2006) (46)
- Purification, characterization, and genetic organization of recombinant Providencia stuartii urease expressed by Escherichia coli (1988) (46)
- Kinetics of Uropathogenic Escherichia coli Metapopulation Movement during Urinary Tract Infection (2012) (46)
- Urease of Enterohemorrhagic Escherichia coli: Evidence for Regulation by Fur and a trans-Acting Factor (2002) (45)
- The high-affinity phosphate transporter Pst in Proteus mirabilis HI4320 and its importance in biofilm formation. (2009) (45)
- Blocking Yersiniabactin Import Attenuates Extraintestinal Pathogenic Escherichia coli in Cystitis and Pyelonephritis and Represents a Novel Target To Prevent Urinary Tract Infection (2015) (45)
- In Vivo Phase Variation of Escherichia coli Type 1 Fimbrial Genes in Women with Urinary Tract Infection (1998) (44)
- pH‐Dependent Protein Profiles of Helicobacter pylori Analyzed by Two‐Dimensional Gels (2000) (44)
- Variable phenotypes of Providencia stuartii due to plasmid-encoded traits (1985) (43)
- A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness (2020) (43)
- Uropathogenic Escherichia coli Suppresses the Host Inflammatory Response via Pathogenicity Island Genes sisA and sisB (2009) (42)
- Helicobacter pylori cadA encodes an essential Cd(II)–Zn(II)–Co(II) resistance factor influencing urease activity (1999) (42)
- Identification of a Modular Pathogenicity Island That Is Widespread among Urease-Producing Uropathogens and Shares Features with a Diverse Group of Mobile Elements (2009) (41)
- Adherence and Colonization (2001) (41)
- Adhesion, Invasion, and Agglutination Mediated by Two Trimeric Autotransporters in the Human Uropathogen Proteus mirabilis (2010) (41)
- Proteus mirabilis fimbriae: N-terminal amino acid sequence of a major fimbrial subunit and nucleotide sequences of the genes from two strains (1993) (41)
- Proteus mirabilis MR/P fimbriae: molecular cloning, expression, and nucleotide sequence of the major fimbrial subunit gene (1993) (40)
- The high-affinity phosphate transporter Pst is a virulence factor for Proteus mirabilis during complicated urinary tract infection. (2008) (40)
- Differential regulation of the Proteus mirabilis urease gene cluster by UreR and H-NS. (2003) (40)
- Use of Green Fluorescent Protein To Assess Urease Gene Expression by Uropathogenic Proteus mirabilis during Experimental Ascending Urinary Tract Infection (1998) (40)
- The Helicobacter pylori flbA flagellar biosynthesis and regulatory gene is required for motility and virulence and modulates urease of H. pylori and Proteus mirabilis. (2002) (39)
- The Repeat-In-Toxin Family Member TosA Mediates Adherence of Uropathogenic Escherichia coli and Survival during Bacteremia (2011) (39)
- Use of Translational Fusion of the MrpH Fimbrial Adhesin-Binding Domain with the Cholera Toxin A2 Domain, Coexpressed with the Cholera Toxin B Subunit, as an Intranasal Vaccine To Prevent Experimental Urinary Tract Infection by Proteus mirabilis (2004) (37)
- Outer Membrane Antigens of the Uropathogen Proteus mirabilis Recognized by the Humoral Response during Experimental Murine Urinary Tract Infection (2008) (37)
- Inhibitors of TonB Function Identified by a High-Throughput Screen for Inhibitors of Iron Acquisition in Uropathogenic Escherichia coli CFT073 (2014) (37)
- UreR, the Transcriptional Activator of the Proteus mirabilis Urease Gene Cluster, Is Required for Urease Activity and Virulence in Experimental Urinary Tract Infections (2003) (36)
- Citrobacter freundii fitness during bloodstream infection (2018) (36)
- Proteus mirabilis ambient-temperature fimbriae: cloning and nucleotide sequence of the aft gene cluster (1996) (35)
- CHAPTER 11 – H. pylori Pathogenesis (2001) (35)
- Pathogenesis of Gram-Negative Bacteremia (2021) (35)
- Interaction of Proteus mirabilis Urease Apoenzyme and Accessory Proteins Identified with Yeast Two-Hybrid Technology (2001) (35)
- Helicobacter pylori Glutamine Synthetase Lacks Features Associated with Transcriptional and Posttranslational Regulation (1998) (34)
- Single-step purification of Proteus mirabilis urease accessory protein UreE, a protein with a naturally occurring histidine tail, by nickel chelate affinity chromatography (1994) (34)
- Anaerobic Respiration Using a Complete Oxidative TCA Cycle Drives Multicellular Swarming in Proteus mirabilis (2012) (33)
- Genetic organization and complete sequence of the Proteus mirabilis pmf fimbrial operon. (1994) (33)
- Secreted proteins and other features specific to uropathogenic Escherichia coli. (2001) (32)
- Identification of the Domains of UreR, an AraC-Like Transcriptional Regulator of the Urease Gene Cluster inProteus mirabilis (2001) (32)
- H-NS Is a Repressor of the Proteus mirabilis Urease Transcriptional Activator GeneureR (2000) (32)
- Transport and incorporation of N-acetyl-D-glucosamine in Bacillus subtilis (1982) (32)
- Proteus mirabilis urease: use of a ureA-lacZ fusion demonstrates that induction is highly specific for urea (1991) (31)
- Determination of Target Sequence Bound by PapX, Repressor of Bacterial Motility, in flhD Promoter Using Systematic Evolution of Ligands by Exponential Enrichment (SELEX) and High Throughput Sequencing* (2011) (31)
- Cloning, Expression, and Catalytic Activity ofHelicobacter hepaticus Urease (2001) (30)
- Internalization of Escherichia coli into human renal tubular epithelial cells. (1988) (30)
- Urease activity of Proteus penneri (1987) (29)
- Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs (2019) (29)
- Proteus mirabilis mannose-resistant, Proteus-like fimbriae: MrpG is located at the fimbrial tip and is required for fimbrial assembly (1997) (28)
- Cell Wall Protein in Bacillus subtilis (1977) (28)
- Self-Transmissibility of the Integrative and Conjugative Element ICEPm1 between Clinical Isolates Requires a Functional Integrase, Relaxase, and Type IV Secretion System (2011) (28)
- The lytic transglycosylase MltB connects membrane homeostasis and in vivo fitness of Acinetobacter baumannii (2018) (28)
- Sequence of the Proteus mirabilis urease accessory gene ureG. (1993) (27)
- TnseqDiff: identification of conditionally essential genes in transposon sequencing studies (2017) (27)
- Cloning and expression of R-factor mediated arsenate resistance in Escherichia coli (2004) (26)
- Measuring Escherichia coli Gene Expression during Human Urinary Tract Infections (2016) (25)
- Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors (2017) (25)
- Adherence to uroepithelial cells of Providencia stuartii isolated from the catheterized urinary tract. (1986) (25)
- Optimization of an Experimental Vaccine To Prevent Escherichia coli Urinary Tract Infection (2020) (24)
- Pathogenesis of Helicobacter pylori infection. (2000) (24)
- Development of a PCR-Restriction Fragment Length Polymorphism Assay Using the Nucleotide Sequence of the Helicobacter hepaticus Urease Structural Genes ureAB (1998) (23)
- Twin arginine translocation, ammonia incorporation, and polyamine biosynthesis are crucial for Proteus mirabilis fitness during bloodstream infection (2019) (23)
- An "omics" approach to uropathogenic Escherichia coli vaccinology. (2009) (23)
- Uropathogenic Escherichia coli Strains Generally Lack Functional Trg and Tap Chemoreceptors Found in the Majority of E. coli Strains Strictly Residing in the Gut (2006) (22)
- Homology among arsenate resistance determinants of R factors in Escherichia coli (1984) (22)
- The Gene Expression Profile of Uropathogenic Escherichia coli in Women with Uncomplicated Urinary Tract Infections Is Recapitulated in the Mouse Model (2020) (21)
- Signature-tagged mutagenesis and co-infection studies demonstrate the importance of P fimbriae in a murine model of urinary tract infection. (2015) (20)
- The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection (2019) (20)
- A Phyletically Rare Gene Promotes the Niche-specific Fitness of an E. coli Pathogen during Bacteremia (2013) (20)
- Arginine promotes Proteus mirabilis motility and fitness by contributing to conservation of the proton gradient and proton motive force (2014) (20)
- Bacterial proteomics and identification of potential vaccine targets (2010) (19)
- Subtle variation within conserved effector operon gene products contributes to T6SS-mediated killing and immunity (2017) (19)
- Involvement of Mismatch Repair in the Reciprocal Control of Motility and Adherence of Uropathogenic Escherichia coli (2012) (19)
- CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII (2018) (19)
- Escherichia coli CFT073 Fitness Factors during Urinary Tract Infection: Identification Using an Ordered Transposon Library (2020) (18)
- Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age (2018) (18)
- Complicated Urinary Tract Infections due to Catheters (2008) (17)
- Contribution of dppA to Urease Activity in Helicobacter pylori 26695 (2005) (17)
- Cell wall-polypeptide complexes in Bacillus subtilis (1983) (16)
- Wounds, functional disability, and indwelling devices are associated with cocolonization by methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in southeast Michigan. (2011) (16)
- Regulation of Expression of Uropathogenic Escherichia coli Nonfimbrial Adhesin TosA by PapB Homolog TosR in Conjunction with H-NS and Lrp (2016) (15)
- MrpB Functions as the Terminator for Assembly of Proteus mirabilis Mannose-Resistant Proteus-Like Fimbriae (1998) (15)
- Draft genome sequences of five recent human uropathogenic Escherichia coli isolates. (2013) (15)
- MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation (2020) (15)
- Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections (2018) (15)
- The Multifunctional Protein YdiV Represses P Fimbria-Mediated Adherence in Uropathogenic Escherichia coli (2013) (15)
- Siderophore Detection Using Chrome Azurol S and Cross-Feeding Assays. (2019) (14)
- Proteus mirabilis urease: histidine 320 of UreC is essential for urea hydrolysis and nickel ion binding within the native enzyme (1993) (14)
- The oxidative fumarase FumC is a key contributor for E. coli fitness under iron-limitation and during UTI (2020) (14)
- PafR, a Novel Transcription Regulator, Is Important for Pathogenesis in Uropathogenic Escherichia coli (2014) (13)
- Cysteine Biosynthesis Controls Serratia marcescens Phospholipase Activity (2017) (13)
- Serum Immunoglobulin Response and Protection from Homologous Challenge by Proteus mirabilis in a Mouse Model of Ascending Urinary Tract Infection (1999) (13)
- A Novel Approach for Transcription Factor Analysis Using SELEX with High-Throughput Sequencing (TFAST) (2012) (13)
- Role of Ethanolamine Utilization Genes in Host Colonization during Urinary Tract Infection (2017) (13)
- Genetic andBiochemical Diversity ofUreases ofProteus, Providencia, andMorganella Species Isolated from Urinary TractInfection (1987) (12)
- TosR-Mediated Regulation of Adhesins and Biofilm Formation in Uropathogenic Escherichia coli (2018) (12)
- Cytolethality of hemolytic Escherichia coli to primary human renal proximal tubular cell cultures obtained from different donors. (1995) (11)
- Transposon Insertion Site Sequencing of Providencia stuartii: Essential Genes, Fitness Factors for Catheter-Associated Urinary Tract Infection, and the Impact of Polymicrobial Infection on Fitness Requirements (2020) (11)
- Lipoteichoic acids from d-glucosylation-defective, cell-wall mutants of Bacillus subtilis (1979) (10)
- Flexible Metabolism and Suppression of Latent Enzymes Are Important for Escherichia coli Adaptation to Diverse Environments within the Host (2019) (9)
- Development of a human stomach explant organ culture system to study the pathogenesis of Helicobacter pylori. (1990) (9)
- A Unique Arabinose 5-Phosphate Isomerase Found within a Genomic Island Associated with the Uropathogenicity of Escherichia coli CFT073 (2011) (9)
- Genomic characterization of asymptomatic Escherichia coli isolated from the neobladder. (2011) (8)
- Ion Extrusion Systems in Bacteria (1985) (8)
- H. pylori urease (1994) (8)
- A Conserved PapB Family Member, TosR, Regulates Expression of the Uropathogenic Escherichia coli RTX Nonfimbrial Adhesin TosA while Conserved LuxR Family Members TosE and TosF Suppress Motility (2014) (7)
- UTI patients have pre-existing antigen-specific antibody titers against UTI vaccine antigens. (2019) (6)
- The Serratia marcescens Siderophore Serratiochelin Is Necessary for Full Virulence during Bloodstream Infection (2020) (6)
- Chapter 9 – Uropathogenic Escherichia coli (2013) (6)
- Plasmid-Encoded Ion Transport Systems (1987) (6)
- Bacterial Pili and Fimbriae (2001) (6)
- Sulfur Assimilation Alters Flagellar Function and Modulates the Gene Expression Landscape of Serratia marcescens (2019) (5)
- MrpJ Directly Regulates Proteus mirabilis Virulence Factors, Including Fimbriae and Type VI Secretion, during Urinary Tract Infection (2018) (5)
- Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder (2017) (5)
- Cross Talk between MarR-Like Transcription Factors Coordinates the Regulation of Motility in Uropathogenic Escherichia coli (2018) (5)
- Replication Dynamics for Six Gram-Negative Bacterial Species during Bloodstream Infection (2021) (5)
- The UDP‐GalNAcA biosynthesis genes gna‐gne2 are required to maintain cell envelope integrity and in vivo fitness in multi‐drug resistant Acinetobacter baumannii (2019) (5)
- The ArcAB Two-Component System: Function in Metabolism, Redox Control, and Infection (2022) (5)
- Characterization ofUreasefromCampylobacter pylori (1988) (4)
- Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments. (2017) (4)
- The ADP-Heptose Biosynthesis Enzyme GmhB is a Conserved Gram-Negative Bacteremia Fitness Factor (2022) (4)
- Proteus mirabilis Overview. (2019) (4)
- Redefining Virulence of Bacterial Pathogens (2015) (4)
- VacA and urease released by H. Pylori stimulate COX-2 expression in macrophages (2001) (4)
- Campylobacter pylori gastritis not related to periodontal disease. (1988) (4)
- Regulation of Klebsiella pneumoniae mucoidy by the bacterial tyrosine kinase Wzc (2022) (4)
- Using Hemagglutination, Surface Shearing, and Acid Treatment to Study Fimbriae in Proteus mirabilis. (2019) (3)
- Identification of distinct capsule types associated with Serratia marcescens infection isolates (2022) (3)
- Ferric Citrate Uptake Is a Virulence Factor in Uropathogenic Escherichia coli (2021) (3)
- Loss of an Intimin-Like Protein Encoded on a Uropathogenic E. coli Pathogenicity Island Reduces Inflammation and Affects Interactions with the Urothelium (2021) (3)
- Insertional Mutagenesis Protocol for Constructing Single or Sequential Mutations. (2019) (3)
- Abstract form for the Irish Journal of Medical Science v workshop on gastroduodenal pathology and Helicobacter pylori July 5th — 7th 1992 — Dublin, Ireland (1992) (3)
- Klebsiella pneumoniae Catheter-Associated Urinary Tract Infections are Associated with Acute Changes in Mental Status (2015) (2)
- Quantitative Profile of the Uropathogenic Escherichia coli Outer Membrane Proteome during Growth in Human Urine (2009) (2)
- How do antibiotics kill bacterial cells but not human cells? (2006) (2)
- Calcium, sodium, phosphate and arsenate transport in cells and vesicles of Escherichia coli. (1984) (2)
- In vitro adhesion of bacteria to exfoliated uroepithelial cells: criteria for quantitative analysis. (1995) (2)
- Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with urinary tract infections (2019) (2)
- Optimization of detection of Campylobacter pylori by urease and DNA hybridization (1989) (2)
- Distinct Commensals Indu ce Interleukin-1 b via NLRP 3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury Graphical Abstract Highlights (1)
- UreI-mediated urea transport in Helicobacter pylori: an open and shut case? (2000) (1)
- Identification of Novel Plasmid Replicons Harboring β-Lactamase Resistant Genes in Ampicillin-Resistant Uropathogenic Escherichia coli (2019) (1)
- CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection (2022) (1)
- Bacterial Genetic Exchange (2001) (1)
- MP71-01 GENETICALLY DIVERSE UROPATHOGENIC ESCHERICHIA COLI ADOPT A COMMON TRANSCRIPTIONAL PROGRAM IN PATIENTS WITH URINARY TRACT INFECTIONS (2019) (1)
- Erratum: Quantitative profile of the uropathogenic escherichia coli outer membrane proteome during growth in human urine (Infection and Immunity:2007(75) (2679:2688) DOI:10.1128/IAI.00076-07) (2009) (1)
- ION‐EXTRUSION SYSTEMS IN Escherichia coli (1982) (1)
- The Multifunctional Protein , YdiV , Represses P Fimbriae-Mediated Adherence in 1 Uropathogenic Escherichia coli 2 3 4 5 6 (2013) (1)
- Helicobacter pylori (1996) (1)
- Differentiation of H. pylori Strains Using PCR RFLP. (1997) (1)
- Green fluorescent protein urea sensors. Uropathogenic Proteus mirabilis. (2002) (1)
- Urease Activity ofProteus penneri (1987) (1)
- H. pylori arginase reguiates NO production by macrophages (2001) (1)
- LB-S&T-35 SIDEROPHORE VACCINE CONJUGATES PROTECT AGAINST UROPATHOGENIC ESCHERICHIA COLI IN A MURINE MODEL OF URINARY TRACT INFECTION (2016) (1)
- Gentamicin Protection Assay to Determine Bacterial Survival within Macrophages (2014) (1)
- Phenotypic Assessment of Clinical Escherichia coli Isolates as an Indicator for Uropathogenic Potential (2022) (1)
- Transposon Insertion Site Sequencing in a Urinary Tract Model. (2019) (1)
- Restricted turnover of the cell wall ofBacillus subtilis (2005) (1)
- Fitness Islands in Uropathogenic Escherichia coli (2011) (1)
- The Klebsiella pneumoniae ter Operon Enhances Stress Tolerance (2022) (1)
- Elvis impersonator? [5] (1991) (0)
- Urinary Tract Infections Caused by Bacterial Species other than E. coli (2002) (0)
- Mice or for Urease Activity Vitro but Is Not Essential for Colonization of Arginase Activity and Acid Protection In Helicobacter pylori rocF Is Required for (2013) (0)
- Citrobacter freundii fitness during bloodstream infection (2018) (0)
- Urease, Urolithiasis, and Colonization of the Urinary Tract (2005) (0)
- THE MECHANISM OF R-FACTOR MEDIATED ARSENATE RESISTANCE IS AN INDUCIBLE ATP-DRIVEN ARSENATE EFFLUX SYSTEM (1985) (0)
- Immortal Sequence (1991) (0)
- VO Modeling and Comparison of Vaccines (2009) (0)
- Editorial: Infection and immunity research at the University of Maryland, Baltimore. (2016) (0)
- E. coli expressing Helicobacter pylori urease is susceptible to acid (1998) (0)
- The structure of fragment B of FdeC (Factor Adherece E. coli), a novel broadly conserved E. coli adhesin, with structural homology to invasin and intimin (2012) (0)
- HUMAN LAMINA PROPRIA MACROPHAGES ARE ACTIVATED BY UREASE FROM HELICOBACTER PYLORI (1995) (0)
- Cloning and Expression of R-Factor Mediated Arsenate Resistance in Escherichia coil (0)
- Testing for Helicobacter pylori in clinical practice. Discussion (1996) (0)
- Conserved Metabolic Regulator ArcA Responds to Oxygen Availability, Iron Limitation, and Cell Envelope Perturbations during Bacteremia (2023) (0)
- strains.sequences of the genes from two acid sequence of a major fimbrial subunit and Proteus mirabilis fimbriae: N-terminal amino (2013) (0)
- 1151 TRANSCRIPTOME OF UROPATHOGENIC ESCHERICHIA COLI DURING HUMAN URINARY TRACT INFECTIONS (2013) (0)
- Vaccination to Protect Against Proteus mirabilis Challenge Utilizing the Ascending Model of Urinary Tract Infection. (2019) (0)
- 10TH International Workshop on Campylobacter, Helicobacter & Related Organisms. (2000) (0)
- CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by <named-content content-type='genus-species'>Acinetobacter baumannii</named-content> That Inactivates Coagulation Factor XII (2018) (0)
- activity . allelic exchange mutagenesis on urease Helicobacter pylori ABC transporter : effect of (1997) (0)
- Detection ofHelicobacter pylori byUsingthe Polymerase ChainReaction (1991) (0)
- Acid resistance in Helicobacter pylori requires an NH3/H2 pump (2000) (0)
- Proteus mirabilis Growth and Swarming Behavior on Minimal Medium (2013) (0)
- Construction of an Ordered Transposon Library for Uropathogenic Proteus mirabilis HI4320 (2022) (0)
- Metal ion resistance of proteus providencia and morganella isolates from urinary tract infection (1987) (0)
- Thehigh-a⁄nityphosphate transporterPst is avirulence factor for Proteusmirabilis during complicatedurinary tract infection (2008) (0)
- Animal Models and Other Helicobacter Species (2001) (0)
- Tract Infection Pyelonephritis in a Murine Model of Urinary Receptor, FyuA, Protects against Immunization with the Yersiniabactin (2014) (0)
- Immortal sequence. (1991) (0)
- RECOVERY FROM NEUROLOGIC IMPAIRMENT IN MURINE MODEL OF CORONAVIRUS-INDUCED DEMYELINATION DOES NOT DIRECTLY CORRELATE WITH IMPROVEMENT OF NEUROGENIC BLADDER DYSFUNCTION: LONG-TERM FOLLOW UP STUDY (2016) (0)
- PLOS Pathogens 2017 Reviewer and Editorial Board Thank You (2018) (0)
- UseofPolymerase ChainReaction-Amplified Helicobacter pylori UreaseStructural GenesforDifferentiation ofIsolates (1992) (0)
- Proteus, Infection and Immunity (1998) (0)
- of UropathogenicEscherichia coli and Survival during Bacteremia (2011) (0)
- Tract : Winning Back the Urinary Escherichia coli Waging War against Uropathogenic (2013) (0)
- Urease Activity is Enhanced During Coculture of Common Catheter-Associated Urinary Tract Infection (CAUTI) Pathogens and Contributes to Severity of Disease in a Murine Infection Model (2016) (0)
- Author response: Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with UTIs (2019) (0)
- Mutants Attenuated at Least 100-Fold Identification of 25 Signature-Tagged Pathogenesis of Urinary Tract Infection : Genes That Contribute to Proteus mirabilis (2004) (0)
- Bacterial Virulence and Pathogenic Mechanisms (2001) (0)
- Expression ofType1Fimbriae MayBeRequired forPersistence of Escherichia coli intheCatheterized Urinary Tract (1987) (0)
- Urinary Tract Infection of Involves IL-17A in a Murine Model Escherichia coli Uropathogenic Innate Immune Response to (2010) (0)
- Defining Helicobacter pylori as a pathogen : Strain hetoerogeneity and virulence. Discussion (1996) (0)
- Energy Metabolism and Synthetic Pathways (2001) (0)
- of the major fimbrial subunit gene . cloning , expression , and nucleotide sequence Proteus mirabilis MR / P fimbriae : molecular (1992) (0)
- A NOVEL FAMILY OF NATURAL PRODUCTS THAT TARGETS UROPATHOGENIC ESCHERISCHIA COLI IRON ACQUISITION: PD12‐01 (2017) (0)
- Cloning ofUreaseGeneSequences fromProvidencia stuartii (1986) (0)
- Human Uropathogen Proteus mirabilis 2 (2010) (0)
- Urinary Tract Infection ofInvolves IL-17 A in a Murine Model Escherichia coliUropathogenic The Innate Immune Response to Subscriptions (2010) (0)
- Augmented Enterocyte Damage During Candida albicans and Proteus mirabilis Coinfection (2022) (0)
- Purification, Characterization, and Genetic Organization of Recombinant Providencia stuartii Urease Expressed by Escherichia colit (0)
- Complete Genome Sequence of Uropathogenic Proteus mirabilis , a Master of both Adherence and Motility (cid:1) † (2008) (0)
- Pathogenesis in the Host, Diagnosis, and Treatment (2001) (0)
- Dietary l-serine confers a competitive fitness advantage to Enterobacteriaceae in the inflamed gut (2019) (0)
- Escherichia coli andKilling ofCultured Human RenalProximal Tubular Epithelial Cells: RoleofHemolysin inSomeStrains (1990) (0)
- Purification of Recombinant Helicobacterpylori Urease (0)
- Book reviews (2005) (0)
- binding within the native enzyme. is essential for urea hydrolysis and nickel ion Proteus mirabilis urease: histidine 320 of UreC (2013) (0)
- Astabiotics: Antimicrobial Signal Transduction Activators (2013) (0)
- Soil survey of Comanehe County, Oklahoma. (1967) (0)
- Summary of Workshop (1996) (0)
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