Haruhiko Koseki
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Computer Science
Haruhiko Koseki's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Haruhiko Koseki's Published Works
Published Works
- Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells (2013) (3424)
- Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells (2006) (2393)
- CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. (1997) (2301)
- A promoter-level mammalian expression atlas (2014) (1664)
- Requirement for Vα14 NKT Cells in IL-12-Mediated Rejection of Tumors (1997) (1302)
- The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA (2007) (1183)
- Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains (2008) (1010)
- Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. (2004) (931)
- Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells (2007) (697)
- Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation (2014) (602)
- Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. (2004) (557)
- Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells. (1998) (507)
- Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells (2015) (502)
- Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. (1997) (455)
- Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing (2006) (419)
- Polycomb Limits the Neurogenic Competence of Neural Precursor Cells to Promote Astrogenic Fate Transition (2009) (418)
- KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands (2012) (411)
- Disruption of the Bcl6 Gene Results in an Impaired Germinal Center Formation (1997) (391)
- Pax genes and organogenesis (1997) (386)
- Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1 (2002) (364)
- The role of Pax-1 in axial skeleton development. (1994) (349)
- Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. (1997) (342)
- Selective reduction of V alpha 14+ NK T cells associated with disease development in autoimmune-prone mice. (1996) (340)
- Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity (2008) (318)
- The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors (2007) (313)
- PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos (2008) (312)
- Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome (2015) (307)
- Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. (2013) (305)
- Targeting Polycomb to Pericentric Heterochromatin in Embryonic Stem Cells Reveals a Role for H2AK119u1 in PRC2 Recruitment (2014) (295)
- UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9 (2013) (294)
- Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. (1995) (291)
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels* (2016) (287)
- Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication (2013) (283)
- A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. (1996) (282)
- Essential roles of the winged helix transcription factor MFH-1 in aortic arch patterning and skeletogenesis. (1997) (266)
- Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance (2014) (258)
- Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells. (2013) (253)
- Dynamic Reprogramming of DNA Methylation at an Epigenetically Sensitive Allele in Mice (2006) (251)
- SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing. (2013) (249)
- Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. (2010) (248)
- Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity (2012) (247)
- The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. (2013) (236)
- Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. (1996) (232)
- The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways (2008) (232)
- Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation. (1999) (230)
- Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells. (2011) (213)
- Mesp2 initiates somite segmentation through the Notch signalling pathway (2000) (207)
- Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression. (2001) (201)
- Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus (2007) (200)
- Angiopoietin-related growth factor antagonizes obesity and insulin resistance (2005) (198)
- Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells (2017) (185)
- Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines (2012) (182)
- Inhibition of T Helper Cell Type 2 Cell Differentiation and Immunoglobulin E Response by Ligand-Activated Vα14 Natural Killer T Cells (1999) (182)
- De novo DNA methylation drives 5hmC accumulation in mouse zygotes (2016) (181)
- Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. (2012) (181)
- PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation (2017) (180)
- A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae. (1993) (180)
- SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. (2012) (179)
- Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation. (2013) (177)
- Novel regulation of MHC class II function in B cells (2007) (176)
- Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders (2013) (174)
- ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency. (2010) (173)
- H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions (2012) (173)
- Senescence marker protein-30 knockout mouse liver is highly susceptible to tumor necrosis factor-alpha- and Fas-mediated apoptosis. (2002) (170)
- Dilated Cardiomyopathy Caused by Aberrant Endoplasmic Reticulum Quality Control in Mutant KDEL Receptor Transgenic Mice (2004) (169)
- Cooperative B7-1/2 (CD80/CD86) and B7-DC Costimulation of CD4+ T Cells Independent of the PD-1 Receptor (2003) (167)
- Involvement of decidual Vα14 NKT cells in abortion (2000) (167)
- In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses (2005) (167)
- The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis. (2011) (161)
- Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression (2019) (154)
- FANTOM5 CAGE profiles of human and mouse samples (2017) (153)
- Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation (2014) (150)
- Generation of Cloned Mice by Direct Nuclear Transfer from Natural Killer T Cells (2005) (149)
- The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells (2014) (147)
- A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin. (2007) (145)
- The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum (2001) (145)
- The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth (2011) (143)
- Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes (2005) (141)
- The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors. (1997) (140)
- Roles of HIPK1 and HIPK2 in AML1‐ and p300‐dependent transcription, hematopoiesis and blood vessel formation (2006) (139)
- Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. (2010) (133)
- CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis. (2011) (131)
- Extrathymic development of V alpha 14-positive T cells (1993) (121)
- Essential requirement of an invariant V alpha 14 T cell antigen receptor expression in the development of natural killer T cells. (1996) (119)
- Homogenous junctional sequence of the V14+ T-cell antigen receptor alpha chain expanded in unprimed mice. (1990) (116)
- Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. (2005) (115)
- FGF9 monomer/dimer equilibrium regulates extracellular matrix affinity and tissue diffusion (2009) (114)
- DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes. (2005) (113)
- Expression of avian Pax1 and Pax9 is intrinsically regulated in the pharyngeal endoderm, but depends on environmental influences in the paraxial mesoderm. (1996) (113)
- Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells (2011) (112)
- Dominant expression of a distinctive V14+ T-cell antigen receptor alpha chain in mice. (1991) (111)
- S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance (2011) (108)
- Growth retardation and skin abnormalities of the Recql4-deficient mouse. (2003) (108)
- Model mice for tissue-specific deletion of the manganese superoxide dismutase (MnSOD) gene. (2002) (108)
- Overlapping Roles for Homeodomain-Interacting Protein Kinases Hipk1 and Hipk2 in the Mediation of Cell Growth in Response to Morphogenetic and Genotoxic Signals (2006) (108)
- A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice. (1997) (107)
- The Generation of Mature, Single-Positive Thymocytes In Vivo Is Dysregulated by CD69 Blockade or Overexpression1 (2002) (107)
- Type II membrane protein CD69 regulates the formation of resting T-helper memory (2012) (105)
- Regulation of Th2 cell differentiation by mel-18, a mammalian polycomb group gene. (2001) (104)
- PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation. (2019) (103)
- Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development. (1999) (103)
- Sall4 Is Essential for Stabilization, But Not for Pluripotency, of Embryonic Stem Cells by Repressing Aberrant Trophectoderm Gene Expression (2009) (103)
- A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities. (2018) (103)
- Inactivation of the Polycomb Group Protein Ring1B Unveils an Antiproliferative Role in Hematopoietic Cell Expansion and Cooperation with Tumorigenesis Associated with Ink4a Deletion (2007) (102)
- Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development (2014) (101)
- PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes (2017) (100)
- Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human (2007) (100)
- Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength (2014) (100)
- Polycomb potentiates meis2 activation in midbrain by mediating interaction of the promoter with a tissue-specific enhancer. (2014) (99)
- Ezh2 is required for neural crest-derived cartilage and bone formation (2014) (99)
- Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice. (2002) (98)
- A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell (2008) (98)
- Targeted disruption of dermatopontin causes abnormal collagen fibrillogenesis. (2002) (97)
- Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate. (2003) (92)
- Cell-autonomous involvement of Mab21l1 is essential for lens placode development (2003) (91)
- Functional annotation of human long noncoding RNAs via molecular phenotyping (2019) (91)
- Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation. (2012) (89)
- PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification. (2018) (88)
- The KDEL Receptor Modulates the Endoplasmic Reticulum Stress Response through Mitogen-activated Protein Kinase Signaling Cascades* (2003) (87)
- Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos (2017) (86)
- Role of SOX17 in hematopoietic development from human embryonic stem cells. (2013) (85)
- Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells. (1995) (84)
- Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells (2007) (84)
- Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity. (2016) (82)
- Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (2010) (82)
- RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells (2012) (81)
- Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs (2016) (81)
- Estrogen, Insulin, and Dietary Signals Cooperatively Regulate Longevity Signals to Enhance Resistance to Oxidative Stress in Mice* (2005) (79)
- Zic1 regulates the patterning of vertebral arches in cooperation with Gli3 (1999) (78)
- Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2 (2006) (77)
- Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis. (2001) (77)
- The role of presenilin 1 during somite segmentation. (2001) (76)
- Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. (2004) (76)
- Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication (2014) (76)
- Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1Bβ and TSLC1 in neuroblastoma (2010) (76)
- Cell Cycle-Dependent Turnover of 5-Hydroxymethyl Cytosine in Mouse Embryonic Stem Cells (2013) (74)
- The role of Bcl6 in mature cardiac myocytes. (1999) (74)
- HP1γ links histone methylation marks to meiotic synapsis in mice (2011) (74)
- Requirement for Mab21l2 during development of murine retina and ventral body wall. (2004) (73)
- Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia (2000) (73)
- The SET1 Complex Selects Actively Transcribed Target Genes via Multivalent Interaction with CpG Island Chromatin (2017) (72)
- Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA. (2016) (71)
- Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress (2016) (70)
- Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing (2013) (70)
- CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. (2003) (70)
- Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity. (2016) (67)
- An epigenetic switch is crucial for spermatogonia to exit the undifferentiated state toward a Kit-positive identity (2013) (66)
- Regulation of Th2 Cell Development by Polycomb Group Gene bmi-1 through the Stabilization of GATA31 (2006) (65)
- Production of monoclonal antibodies against mammalian Ring1B proteins. (2001) (65)
- Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP (2007) (65)
- Protective Role of Macrophages in Noninflammatory Lung Injury Caused by Selective Ablation of Alveolar Epithelial Type II Cells1 (2007) (64)
- A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development (2012) (64)
- Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFκB transcription factors (2004) (63)
- Oxygen Affinity of Hemoglobin Regulates O2Consumption, Metabolism, and Physical Activity* (2003) (63)
- Abnormal blood vessel development in mice lacking presenilin-1 (2003) (63)
- Involvement of decidual Valpha14 NKT cells in abortion. (2000) (62)
- Polycomb Repressive Complexes Restrain the Expression of Lineage-Specific Regulators in Embryonic Stem Cells (2006) (62)
- Predominant use of a particular alpha-chain in suppressor T cell hybridomas specific for keyhole limpet hemocyanin. (1989) (61)
- Maintenance of Undifferentiated State and Self‐Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring1B (2009) (61)
- Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing. (2007) (60)
- Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses (2017) (60)
- topors, a p53 and topoisomerase I-binding RING finger protein, is a coactivator of p53 in growth suppression induced by DNA damage (2005) (59)
- CCN3 Inhibits Neointimal Hyperplasia Through Modulation of Smooth Muscle Cell Growth and Migration (2010) (59)
- A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. (2008) (59)
- The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development (2014) (59)
- Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes (2006) (59)
- Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells. (2010) (58)
- Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos (1995) (58)
- Development of Valpha4+ NK T cells in the early stages of embryogenesis. (1996) (57)
- WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation. (2013) (55)
- Nuclear Inhibitor of Protein Phosphatase-1 (NIPP1) Directs Protein Phosphatase-1 (PP1) to Dephosphorylate the U2 Small Nuclear Ribonucleoprotein Particle (snRNP) Component, Spliceosome-associated Protein 155 (Sap155)* (2008) (55)
- A Novel Gene Essential for the Development of Single Positive Thymocytes (2009) (55)
- CRTAM Confers Late-Stage Activation of CD8+ T Cells to Regulate Retention within Lymph Node1 (2009) (55)
- Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice. (2018) (55)
- Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors. (2012) (54)
- MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle‐dependent phosphorylation (2002) (53)
- Altered Quality Control in the Endoplasmic Reticulum Causes Cortical Dysplasia in Knock-In Mice Expressing a Mutant BiP (2007) (53)
- Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex. (2018) (53)
- Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness. (2008) (53)
- An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells (2017) (53)
- Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells. (2011) (52)
- Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias. (2016) (52)
- Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif. (1993) (51)
- Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. (2004) (51)
- Three developmental compartments involved in rib formation. (2005) (51)
- Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes (2011) (51)
- Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release. (2021) (50)
- Overlapping Roles of the Methylated DNA-binding Protein MBD1 and Polycomb Group Proteins in Transcriptional Repression of HOXA Genes and Heterochromatin Foci Formation* (2007) (49)
- Polycomb directs timely activation of germline genes in spermatogenesis (2017) (48)
- Extrathymic Differentiation of a T Cell Bearing Invariant Vα14Jα281 TCR (1994) (48)
- The Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution (2007) (48)
- Efficient Regeneration of Human Vα24+ Invariant Natural Killer T Cells and Their Anti‐Tumor Activity In Vivo (2016) (47)
- Roles of histone H3K27 trimethylase Ezh2 in retinal proliferation and differentiation (2015) (46)
- Requirement of Zinc Transporter SLC39A7/ZIP7 for Dermal Development to Fine-Tune Endoplasmic Reticulum Function by Regulating Protein Disulfide Isomerase. (2017) (46)
- Presenilin 1 is essential for cardiac morphogenesis (2004) (46)
- Phenotypes and invariant alpha beta TCR expression of peripheral V alpha 14+ NK T cells. (1997) (46)
- Divergence of CpG island promoters: A consequence or cause of evolution? (2010) (45)
- Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity (2020) (44)
- CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability (2015) (44)
- Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression. (2013) (44)
- Haploinsufficiency of Sf3b1 leads to compromised stem cell function but not to myelodysplasia (2014) (44)
- Depletion of Sf3b1 impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia. (2014) (43)
- Inductive signals from the somatopleure mediated by bone morphogenetic proteins are essential for the formation of the sternal component of avian ribs. (2001) (43)
- Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway. (2018) (42)
- Molecular cloning and characterization of the gene encoding mouse melanoma antigen by cDNA library transfection. (1992) (42)
- Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells (2014) (42)
- NOV/CCN3: A New Adipocytokine Involved in Obesity-Associated Insulin Resistance (2016) (42)
- Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis (2017) (42)
- H2AK119ub1 guides maternal inheritance and zygotic deposition of H3K27me3 in mouse embryos (2021) (42)
- Fc receptor beta subunit is required for full activation of mast cells through Fc receptor engagement. (1999) (42)
- Recruitment of PRC 1 function at the initiation of X inactivation independent of PRC 2 and silencing (2013) (41)
- Reproductive Isolation in Hybrid Mice Due to Spermatogenesis Defects at Three Meiotic Stages (2010) (41)
- Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8 (2006) (41)
- Identification of loss-of-function mutations of SLC35D1 in patients with Schneckenbecken dysplasia, but not with other severe spondylodysplastic dysplasias group diseases (2009) (41)
- Internal deletion of BCOR reveals a tumor suppressor function for BCOR in T lymphocyte malignancies (2017) (41)
- Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis. (2016) (41)
- Accumulation of p27KIP1 is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines (2003) (40)
- Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase (2003) (40)
- Histone H2A T120 Phosphorylation Promotes Oncogenic Transformation via Upregulation of Cyclin D1. (2016) (40)
- CCN3 Protein Participates in Bone Regeneration as an Inhibitory Factor* (2013) (38)
- Expression of the Dan gene during chicken embryonic development (2001) (38)
- Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells (2012) (38)
- An essential role for REV3 in mammalian cell survival: absence of REV3 induces p53-independent embryonic death. (2002) (37)
- Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation (2015) (37)
- Recruitment of Dnmt1 roles of the SRA protein Np95 (Uhrf1) and other factors. (2011) (36)
- Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin‐1‐deficient mice (2002) (36)
- Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes. (2020) (35)
- Generation of Tumor Antigen-Specific iPSC-Derived Thymic Emigrants Using a 3D Thymic Culture System. (2018) (35)
- A Novel Zinc Finger Protein Zfp277 Mediates Transcriptional Repression of the Ink4a/Arf Locus through Polycomb Repressive Complex 1 (2010) (34)
- Correction: The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways (2008) (34)
- Gab2, via PI-3K, Regulates ARF1 in FcεRI-Mediated Granule Translocation and Mast Cell Degranulation (2011) (34)
- Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways (2017) (33)
- Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development (2014) (33)
- Is there a role for endogenous retroviruses to mediate long-term adaptive phenotypic response upon environmental inputs? (2013) (33)
- Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells (2016) (33)
- Generation of functional NKT cells in vitro from embryonic stem cells bearing rearranged invariant Valpha14-Jalpha18 TCRalpha gene. (2010) (33)
- Late-Onset of Spinal Neurodegeneration in Knock-In Mice Expressing a Mutant BiP (2014) (33)
- Analysis of LacZ reporter genes in transgenic embryos suggests the presence of several cis‐acting regulatory elements in the murine Hoxb‐6 gene (1993) (32)
- KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR (2015) (32)
- MAPKAP kinase MK2 maintains self‐renewal capacity of haematopoietic stem cells (2009) (31)
- Polycomb Group Protein Ezh2 Regulates Hepatic Progenitor Cell Proliferation and Differentiation in Murine Embryonic Liver (2014) (31)
- Pramel7 mediates ground-state pluripotency through proteasomal–epigenetic combined pathways (2017) (31)
- Human NK cell development in hIL-7 and hIL-15 knockin NOD/SCID/IL2rgKO mice (2019) (30)
- PRC1 preserves epidermal tissue integrity independently of PRC2 (2018) (30)
- Pivotal Role of IL-22 Binding Protein in the Epithelial Autoregulation of Interleukin-22 Signaling in the Control of Skin Inflammation (2018) (30)
- Irxl1 mutant mice show reduced tendon differentiation and no patterning defects in musculoskeletal system development (2011) (29)
- Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome. (2018) (29)
- Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication (2014) (28)
- Pax-1 in the development of the cervico-occipital transitional zone (1995) (27)
- Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis (2019) (27)
- Identification, Tissue Expression, and Functional Characterization of Otx3, a Novel Member of the Otx Family* (2002) (27)
- Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine. (2006) (27)
- A novel de novo point mutation of the OCT‐binding site in the IGF2/H19‐imprinting control region in a Beckwith–Wiedemann syndrome patient (2014) (27)
- Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity (2017) (27)
- EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice (2017) (27)
- A gene‐targeting approach for functional characterization of KIAA genes encoding extremely large proteins (2006) (27)
- Bmi1 regulates cell fate via tumor suppressor WWOX repression in small‐cell lung cancer cells (2011) (27)
- Erratum: Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells (2014) (27)
- Polycomb in Transcriptional Phase Transition of Developmental Genes. (2016) (26)
- Induction of Wnt5a-Expressing Mesenchymal Cells Adjacent to the Cloacal Plate Is an Essential Process for Its Proximodistal Elongation and Subsequent Anorectal Development (2009) (26)
- Reduced NOV/CCN3 Expression Limits Inflammation and Interstitial Renal Fibrosis after Obstructive Nephropathy in Mice (2015) (26)
- Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development (2019) (26)
- Polycomb Group Gene Product Ring1B Regulates Th2-Driven Airway Inflammation through the Inhibition of Bim-Mediated Apoptosis of Effector Th2 Cells in the Lung (2010) (25)
- Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program (2016) (25)
- Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method. (2002) (25)
- Generation of Novel Traj18-Deficient Mice Lacking Vα14 Natural Killer T Cells with an Undisturbed T Cell Receptor α-Chain Repertoire (2016) (25)
- Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation (2007) (25)
- PLD4 is a genetic determinant to systemic lupus erythematosus and involved in murine autoimmune phenotypes (2019) (23)
- Accumulation of p27 KIP1 is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines. (2003) (23)
- Dual Functions of the RFTS Domain of Dnmt1 in Replication-Coupled DNA Methylation and in Protection of the Genome from Aberrant Methylation (2015) (23)
- Elbow knee synostosis (Eks): a new mutation on mouse Chromosome 14 (2002) (23)
- Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts (2014) (23)
- A new Pax gene, Pax-9, maps to mouse Chromosome 12 (2004) (22)
- Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs. (2003) (22)
- Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ–TIF2 fusion (2013) (22)
- ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells (2016) (21)
- Presenilin‐1 controls the growth and differentiation of endothelial progenitor cells through its β‐catenin‐binding region (2006) (21)
- Polycomb group molecule PHC3 regulates polycomb complex composition and prognosis of osteosarcoma (2010) (21)
- KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis. (2019) (21)
- Clustering of CARMA1 through SH3–GUK domain interactions is required for its activation of NF-κB signalling (2015) (21)
- Ezh 2 is required for neural crest-derived cartilage and bone formation (21)
- FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment (2018) (19)
- Bone Marrow Allograft Rejection Mediated by a Novel Murine NK Receptor, NKG2I (2004) (19)
- Randomly inserted and targeted Hox/reporter fusions transcriptionally silenced in Polycomb mutants (2003) (19)
- Vα14+ NK T cells: A novel lymphoid cell lineage with regulatory function (1996) (18)
- Extrathymic differentiation of a T cell bearing invariant V alpha 14J alpha 281 TCR. (1994) (18)
- Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs (2014) (18)
- Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3 (2007) (17)
- KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity (2019) (17)
- The mouse Edr2 (Mph2) gene has two forms of mRNA encoding 90- and 36-kDa polypeptides. (2002) (17)
- Ezh 2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia (2012) (17)
- Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation. (2021) (16)
- PCGF 3 / 5 – PRC 1 initiates Polycomb recruitment in X chromosome inactivation (2017) (16)
- Polycomb complexes redundantly maintain epidermal stem cell identity during development (2021) (16)
- Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells. (2001) (16)
- Human Gain-of-Function STAT1 Mutation disturbs IL-17 Immunity in Mice. (2019) (16)
- Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. (2003) (15)
- Monoclonol antibody against murine T cell receptor Vα14 cross-reacts with human CD3θ and detects disulfide-linked dimeric form (1991) (15)
- Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells (2016) (15)
- Correction: PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes (2017) (15)
- The USP21 Short Variant (USP21SV) Lacking NES, Located Mostly in the Nucleus In Vivo, Activates Transcription by Deubiquitylating ubH2A In Vitro (2013) (15)
- Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality (2022) (15)
- Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb. (2002) (15)
- RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression (2016) (15)
- Heat shock-induced homeotic transformations of the axial skeleton and associated shifts of Hox gene expression domains in mouse embryos. (1997) (14)
- Induced pluripotency as a potential path towards iNKT cell-mediated cancer immunotherapy (2012) (14)
- Double-step and inverse polymerase chain reaction for sensitive detection and cloning of T cell receptor variable region sequences. (1991) (14)
- Ring1B promotes hepatic stem/progenitor cell expansion through simultaneous suppression of Cdkn1a and Cdkn2a in mice (2014) (14)
- Co-activation of macrophages and T cells contribute to chronic GVHD in human IL-6 transgenic humanised mouse model (2019) (14)
- Variant PRC1 competes with retinoic acid-related signals to repress Meis2 in the mouse distal forelimb bud (2018) (14)
- Molecular cloning, genetic mapping, and expression of the mouse Sf3b1 (SAP155) gene for the U2 snRNP component of spliceosome (2001) (14)
- Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR (2018) (13)
- Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes (2021) (13)
- Ring1A and Ring1B inhibit expression of Glis2 to maintain murine MOZ-TIF2 AML stem cells. (2018) (13)
- Characterization of Np95 expression in mouse brain from embryo to adult: A novel marker for proliferating neural stem/precursor cells (2014) (13)
- Nuclear transcriptome profiling of induced pluripotent stem cells and embryonic stem cells identify non-coding loci resistant to reprogramming (2015) (13)
- The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon (2019) (13)
- Deep phenotyping of myalgic encephalomyelitis/chronic fatigue syndrome in Japanese population (2020) (13)
- Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis (2015) (12)
- Embracing change to remain the same: conservation of polycomb functions despite divergence of binding motifs among species. (2013) (12)
- CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats (2020) (12)
- Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing (2021) (12)
- Expansion of murine T cells bearing a unique T cell receptor beta-chain in Friend virus-induced tumor in situ. (1992) (11)
- DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell–related genes in mouse embryonic stem cells (2018) (11)
- TISSUE-SPECIFIC STEM CELLS Maintenance of Undifferentiated State and Self-Renewal of Embryonic Neural Stem Cells by Polycomb Protein Ring 1 B (2009) (11)
- Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. (2004) (10)
- Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch. (2003) (10)
- Unique composition of polycomb repressive complex 1 in hematopoietic stem cells (2007) (10)
- Hemimethylation: DNA's lasting odd couple (2018) (10)
- Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression (2019) (10)
- Maintenance DNA methylation in pre-meiotic germ cells regulates meiotic prophase by facilitating homologous chromosome pairing. (2021) (10)
- Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice. (2004) (10)
- The genetics of skeletal development. (1993) (9)
- CXCR4-Expressing Anti-CD25 CAR T-Cells Effectively Eliminate Human AML Cells In Vivo (2020) (9)
- Molecular pathogenesis of progression to myeloid leukemia from TET-insufficient status. (2020) (9)
- The mouse YAF2 gene generates two distinct transcripts and is expressed in pre-and postimplantation embryos. (2003) (9)
- Epigenetic memory meets G2/M: to remember or to forget? (2011) (8)
- Reduction of SNAP25 in acid secretion defect of Foxl1-/- gastric parietal cells. (2004) (8)
- Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF4. (2020) (8)
- UV-induced reduction in Polycomb repression promotes epidermal pigmentation. (2021) (8)
- Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression (2019) (8)
- Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation. (2006) (8)
- Autoreactive T-cell clones which suppress cytotoxic T cell responses. (1991) (8)
- Enhanced Th2 Cell Differentiation and Allergen-Induced Airway Inflammation in Zfp35-Deficient Mice1 (2009) (8)
- Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation. (2015) (7)
- CNOT 3 contributes to early B cell development by controlling Igh rearrangement and p 53 mRNA stability (2015) (7)
- Effects of BMP7 Produced by Group 2 Innate Lymphoid Cells on Adipogenesis. (2020) (7)
- Mast Cell Degranulation RI-Mediated Granule Translocation and ε Gab 2 , via PI-3 K , Regulates ARF 1 in (2011) (6)
- Reduced inflammatory pain in mice deficient in the differential screening-selected gene aberrative in neuroblastoma (2004) (6)
- Generation of induced pluripotent stem cell-derived mice by reprogramming of a mature NKT cell (2014) (6)
- Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice (2019) (6)
- Effects of growth hormone dose after major abdominal operation: a randomized, prospective, multicenter trial (1992) (6)
- Identification of the Coiled‐Coil Domain as an Essential Methyl‐CpG‐Binding Domain Protein 3 Element for Preserving Lineage Commitment Potential of Embryonic Stem Cells (2018) (6)
- V alpha 14+ NK T cells: a novel lymphoid cell lineage with regulatory function. (1996) (6)
- The Cxxc1 subunit of the Trithorax complex directs epigenetic licensing of CD4+ T cell differentiation (2021) (6)
- CFC1 is a cancer stemness-regulating factor in neuroblastoma (2017) (6)
- Mammal-specific H2A Variant, H2ABbd, Is Involved in Apoptotic Induction via Activation of NF-κB Signaling Pathway* (2014) (5)
- Establishment of mouse stem cells that can recapitulate the developmental potential of primitive endoderm (2022) (5)
- Osteoclasts adapt to physioxia perturbation through DNA demethylation (2021) (5)
- Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis. (2022) (5)
- Live Imaging of Xist RNA. (2018) (4)
- DJ‐1 depletion prevents immunoaging in T‐cell compartments (2022) (4)
- Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection (2022) (4)
- MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells (2021) (4)
- Chromatin and epigenetics in development: a Special Issue (2019) (4)
- Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes (2014) (4)
- Association of SF3B1 with Ring Sideroblasts in patients, In Vivo, and In Vitro models of Spliceosomal Dysfunction (2011) (4)
- A unique expression pattern of Tbx10 in the hindbrain as revealed by Tbx10LacZ allele (2010) (4)
- Monoclonal antibody against murine T cell receptor V alpha 14 cross-reacts with human CD3 epsilon and detects disulfide-linked dimeric form. (1991) (4)
- Genome-wide analysis of target genes regulated by HoxB 4 in hematopoietic stem and progenitor cells developing from embryonic stem cells (2011) (4)
- PCL2 regulates p53 stability and functions as a tumor suppressor in breast cancer. (2018) (4)
- Depletion of Sf 3 b 1 impairs proliferative capacity of hematopoietic stem cells but is not suf fi cient to induce myelodysplasia (2014) (3)
- Report on STAP Cell Research Paper Investigation (2014) (3)
- Pillars article: homogenous junctional sequence of the V14+ T-cell antigen receptor α chain expanded in unprimed mice. Proc. Natl. Acad. Sci. U.S.A. 1990. 87: 5248-5252. (2014) (3)
- Physical interaction between MPP8 and PRC1 complex and its implication for regulation of spermatogenesis. (2015) (3)
- Pivotal role of CD103 in the development of psoriasiform dermatitis (2020) (3)
- Essential Role of STAT3 Signaling in Hair Follicle Homeostasis (2021) (3)
- Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis (2021) (3)
- Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice (2021) (3)
- Np95/Uhrf1 regulates tumor suppressor gene expression of neural stem/precursor cells, contributing to neurogenesis in the adult mouse brain (2019) (3)
- Development of the vertebral column: Morphogenesis and genes (1996) (3)
- Rewriting the past: de novo activity of PRC2 restores global H3K27 methylation patterns (2018) (2)
- Expression of the proliferation-related Ki-67 mRNA in the early development of murine embryo. (1997) (2)
- The USP 21 Short Variant ( USP 21 SV ) Lacking NES , Located Mostly in the Nucleus In Vivo , Activates Transcription by Deubiquitylating ubH 2 A In Vitro (2017) (2)
- Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells (2010) (2)
- Evolution of Vα14 TCR Gene Family in Mice (1994) (2)
- Residual Wild-Type Tet2/Tet3 Allele Is the Savior Preventing Mouse Hematopoietic Progenitor Cells from Leukemia Development (2018) (2)
- Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2021) (2)
- No Winter Lasts Forever: Polycomb Complexes Convert Epigenetic Memory of Cold into Flowering. (2017) (2)
- TCR repertoire in early fetal mouse thymus. (1995) (2)
- Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1 (2016) (2)
- Molecular analysis of suppressor T cell receptors. (1988) (2)
- Isolation of Genomic DNA Controlling Mouse Melanoma Antigen Defined by Monoclonal Antibody (1988) (2)
- Splicing Factor 3b Subunit 1 (SF3B1) Heterozygous Mice Manifest a Hematologic Phenotype Similar To Low Risk Myelodysplastic Syndromes With Ring Sideroblasts (2013) (2)
- Srsf2 P95H Mutation Causes Impaired Stem Cell Repopulation and Hematopoietic Differentiation in Mice (2015) (2)
- Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development (2020) (2)
- IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse. (2022) (2)
- The Trithorax-Group Protein ASH1L Regulates Hematopoietic Stem Cell Homeostasis Independently of Its Histone Methyltransferase Activity (2018) (2)
- Insufficiency of non-canonical PRC1 synergizes with JAK2V617F in the development of myelofibrosis (2021) (2)
- RING 1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis 2 expression (2016) (2)
- Efficient Production of Functional Human NKT Cells from Induced Pluripotent Stem Cells - Reprogramming of Human Vα24+iNKT Cells. (2017) (2)
- Microbiota-Independent Spontaneous Dermatitis Associated With Increased Sebaceous Lipid Production in Tmem79-Deficient Mice. (2022) (2)
- Accelerated acquisition of permeability barrier function in the skin of presenilin-1-deficient embryos (2006) (1)
- Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages. (2023) (1)
- HEMATOPOIESIS AND STEM CELLS Role of SOX 17 in hematopoietic development from human embryonic stem cells (2013) (1)
- Blockade or Overexpression CD69 Thymocytes In Vivo Is Dysregulated by The Generation of Mature, Single-Positive (2013) (1)
- Stem cell epigenetics: looking forward. (2014) (1)
- Novel Member of the Otx Family 1 Otx 3 : identification , tissue expression and functional characterization of a novel member of the Otx family Running title : Otx 3 , a novel member of the Otx family (2002) (1)
- In utero gene transfer system for embryos before neural tube closure reveals a role for Hmga2 in the onset of neurogenesis (2020) (1)
- Overlapping Roles for Homeodomain-Interacting Protein Kinases Hipk1 and Hipk2 in the Mediation of Cell Growth in Response to Morphogenetic and Genotoxic Signals (2014) (1)
- H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions (2012) (1)
- Supplemental Information Polycomb Potentiates Meis 2 Activation in Midbrain by Mediating Interaction of the Promoter with a Tissue-Specific Enhancer (2013) (1)
- Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling (2021) (1)
- Biological Characterization of the U2af1 S34F Mutation in the Pathogenesis of Myelodysplasia (2018) (1)
- Generation of a monoclonal antibody against the mouse Sf3b1 (SAP155) gene product for U2 snRNP component of spliceosome. (2003) (1)
- [Role of mammalian polycomb group gene products in embryo genesis]. (2005) (1)
- Fine genetic mapping of the proximal part of mouse Chromosome 2 excludes Pax-8 as a candidate gene for Danforth's short tail (Sd) (2004) (1)
- Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity (2020) (1)
- Method of Genomic DNA Cloning by the Combination of Cosmid Shuttle Vector and Monoclonal Antibody (1988) (1)
- [Application of iPS Cell-Derived NKT Cells to Cancer Immunotherapy]. (2020) (1)
- A role for Hmga2 in the early-stage transition of neural stem-progenitor cell properties during mouse neocortical development (2020) (1)
- Polycomb suppresses a female gene regulatory network to ensure testicular differentiation (2021) (1)
- Roles of Ring1A/B on Stem Cell Potential of MOZ and Other Acute Myeloid Leukemias, (2011) (0)
- Genetic background-dependent abnormalities of the enteric nervous system and intestinal function in Kif26a-deficient mice (2021) (0)
- The influences of valiant PRC1 molecule defect during ES cell differentiation (2015) (0)
- Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis (2022) (0)
- S132 BIOLOGICAL CHARACTERIZATION OF THE U2AF1 S34F MUTATION IN THE PATHOGENESIS OF MYELODYSPLASIA (2019) (0)
- Title Requirement of Stat 3 Signaling in the Postnatal Developmentof Thymic Medullary Epithelial Cells (2019) (0)
- [Epigenetic regulation during spermatogenesis]. (2007) (0)
- Structural basis for activation of DNMT1 (2022) (0)
- Coordination of growth factor signaling and cell death during vertebrate rib development (2011) (0)
- Generation of Melanoma Antigen Specific T Cells From Human Ips Cells Using a Feeder Free System. (2012) (0)
- V-Alpha-14 T-Cell Antigen Receptor Repertoire and Its Function. (1992) (0)
- Bridging multiple dimensions: roles of transposable elements in higher-order genome regulation. (2023) (0)
- assay information of the mouse qualitycontrol samples for HeliScopeCAGE (2017) (0)
- PCGF6-PRC1 suppresses premature differentiation of embryonic stem cells by silencing germ cell-related genes (2016) (0)
- Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR (2018) (0)
- Mammal-specificH2AVariant,H2ABbd,IsInvolvedinApoptotic InductionviaActivationofNF-BSignalingPathway * □ (2014) (0)
- Intracellular virus sensor MDA5 mutation develops autoimmune myocarditis and nephritis. (2022) (0)
- The histone methyltransferase Ezh2 regulates differentiation and plasticity of CD4 T helper cells. (P1334) (2013) (0)
- Role of KDM2B and Non-Canonical PRC1.1 As a Tumor Suppressor in T-ALL (2018) (0)
- Stag2 regulates Hematopoietic Differentiation and Self-Renewal (2017) (0)
- Corrigendum: Pramel7 mediates ground-state pluripotency through proteasomal–epigenetic combined pathways (2017) (0)
- Author Correction: Pivotal role of CD103 in the development of psoriasiform dermatitis (2020) (0)
- An interview with Haruhiko Koseki. Interviewed by Eva Amsen. (2012) (0)
- Insufficiency of Non-Canonical PRC1 Complex Cooperates with an Activating JAK2 Mutation in the Pathogenesis of Myelofibrosis (2018) (0)
- Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders (2022) (0)
- HP1 deficiency results in De-Repression of Endogenous Retroviruses and Induction of Neurodegeneration via Complement (2022) (0)
- PRC1-mediated epigenetic programming is required to generate the ovarian reserve (2022) (0)
- 162 Application of microdissection-based spatial transcriptomics for mechanistic and biomarker investigations in dermatology (2021) (0)
- Rewriting the past: de novo activity of PRC2 restores global H3K27 methylation patterns (2018) (0)
- Technologies to dissect cell lineages of dynamic cell progression in complex systems (2017) (0)
- Pivotal role of CD103 in the development of psoriasiform dermatitis (2020) (0)
- Hematopoietic stem cells (+iPS) (WS-010) Chairpersons: Hiromitsu Nakauchi, Haruhiko Koseki (2010) (0)
- [Application of iPS cell technology for NKT cell-targeted adjuvant therapy in mice]. (2010) (0)
- Factors and Mechanisms That Influence Chromatin-Mediated Enhancer–Promoter Interactions and Transcriptional Regulation (2022) (0)
- Extrathymic Development of Vcd 4-positive T Cells (2003) (0)
- Involvement of Polycomb factors in promoter activation step of developmental regulator genes (2015) (0)
- genomic coordinates of the human CAGE peaks (2017) (0)
- MORC3, a novel MIWI2 association partner, is an epigenetic regulator of piRNA-dependent transposon silencing. (2020) (0)
- P39. Enhancer of Polycomb 1 is essential for spermiogenesis by regulating histone hyperacetylation status (2010) (0)
- expression table of the human CAGE peaks (2017) (0)
- Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs (2014) (0)
- Correction (2014) (0)
- Author response: KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands (2012) (0)
- Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8 (2014) (0)
- 290 A novel iPSC-derived CAR-invariant natural killer T (iNKT) cell therapy platform for hematologic malignancies and solid tumors (2022) (0)
- 3124 – POLYCOMB REPRESSIVE COMPLEX 1.1 INSUFFICIENCY PROMOTES THE DEVELOPMENT OF MYELOFIBROSIS (2021) (0)
- Role Of Sf3b1 On Hematopoiesis (2013) (0)
- O12. Polycomb-dependent regulation for differentiation programs of stem cells and progenitors (2010) (0)
- Transcription of mouse Zrsr1 DMR results in its methylation in oocyte but does not in somatic cells. (2017) (0)
- Functional Roles of DDX41 Mutations in the Development of Myeloid Malignancies (2021) (0)
- Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death. (2022) (0)
- Production of monoclonal antibodies against quail Pax-1. (1996) (0)
- New plexin polypeptide of this coding dna and use them (2004) (0)
- DJ-1 depletion prevents immunoaging in T-cell compartments (0)
- Derivation of primitive endoderm stem cells in mice (2017) (0)
- Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1 (2016) (0)
- Solution structure of the TUDOR domain of Metal-response element-binding transcription factor 2 (2008) (0)
- University of Dundee Crosstalk between NRF 2 and HIPK 2 shapes cytoprotective responses (2017) (0)
- Anti-HIV-1 Activity of A3G is Enhanced by HSP70 (2009) (0)
- Homeostatic pruning and activity of epidermal nerves are dysregulated in barrier-impaired skin during chronic itch development (2019) (0)
- Variant Pcgf-PRC1 Regulates Susceptibility of PRC2 Mediated H3K27me3 to Safeguard B Cell Fate of Hematopoietic Stem/Progenitor Cells (2019) (0)
- Role of the Epigenetic Modifier EZH2 in Melanoma (2013) (0)
- Generation of TRAF5 deficient mice by gene targeting. (1998) (0)
- Epigenetics in development: Decorating the genome to show or hide? (2010) (0)
- TOPORS (topoisomerase I binding, arginine/serine-rich) (2011) (0)
- Essential role of Uhrf1 during oocyte growth and preimplantation development (2016) (0)
- Towards high-resolution whole cell lineage tracing of mammalian development using genome editing and evolving DNA barcode technology (2017) (0)
- T1783 Kif26a-Deficient Mice Develop Megacolon Associated with Dysfunction of Enteric Neuronal Cells in the Colon (2009) (0)
- Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
- FBXL19 recruits CDK-Mediator to the CpG islands of developmental genes to prime them for activation during lineage commitment (2018) (0)
- Mouse genetics and the development of vertebral column development (1994) (0)
- The histone H3K36 demethylase Fbxl11 plays pivotal roles in the development of retinal late-born cell types. (2023) (0)
- Contents, Vol. 99, 1992 (1992) (0)
- 864 Catalytic-dependent and -independent activities of Polycomb repressive complex 1 differentially regulate skin stem cell specification (2017) (0)
- genomic coordinates of the mouse CAGE peaks (2017) (0)
- Epigenetic regulation of meiosis-related genes by an atypical PRC1-type Polycomb complex assembled by MBLR (2015) (0)
- Spermatogenic disruptions at three meiotic stages in hybrid males between house mouse subspecies or species (2010) (0)
- Deficient Mice Zfp 35 Allergen-Induced Airway Inflammation in Enhanced Th 2 Cell Differentiation and Ohara (2009) (0)
- CD1d/NKT cells (WS-006) Chairpersons: Ken-ichiro Seino, Dale Godfrey (2010) (0)
- H2A ubiquitination alters H3-tail dynamics on linker-DNA to enhance H3K27 methylation. (2023) (0)
- Mammalian Polyhomeotic Homologues Phc2 and Phc1 Act in Synergy To Mediate Polycomb Repression of Hox Genes (2014) (0)
- Genomic DNA with transformation-related activity and melanoma antigen expression. (1989) (0)
- 837 Micro-regional transcriptome reveals local dermal-epidermal intercorrelation in atopic dermatitis (2020) (0)
- MOUSE DEVELOPMENT,GENETICS & GENOMICS (2010) (0)
- Application of iPS technology for human NKT cell generation and dynamics of iPS-NKT cells in vivo. (2017) (0)
- Membrane-Bound Human Stem Cell Factor Promotes Differentiation of Human Granulocytes and Mast Cells In Vivo, (2011) (0)
- Stabilization of GATA3 Polycomb Group Gene bmi-1 through the Regulation of Th2 Cell Development by (2013) (0)
- Efficient regeneration of Human Vα24(+) invariant NKT cells and their anti-tumor activity in vivo. (2016) (0)
- DEV115667 3431..3436 (2014) (0)
- The Hbo1-Brd1/Brpf2 HAT Complex Is Required for Erythropoiesis In Fetal Liver (2010) (0)
- Correction (2004) (0)
- Role of Kdm2b, a component of non-canonical PRC1.1, in hematopoiesis (2017) (0)
- Polycomb suppresses a female gene regulatory network in Sertoli cells (2019) (0)
- Genetic, Genomic, and Imaging Approaches to Dissect the Role of Polycomb Group Epigenetic Regulators in Mice. (2022) (0)
- Abstract: P246 CCN3 INHIBITS NEOINTIMAL HYPERPLASIA THROUGH MODULATION OF SMOOTH MUSCLE CELL GROWTH AND MIGRATION (2009) (0)
- Functional Characterization of Compound DDX41 Germline and Somatic R525H Mutations in the Development of Myeloid Malignancies (2020) (0)
- PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment (2022) (0)
- Nature Butyrate Supplementary Information (2013) (0)
- Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis (2019) (0)
- Reduced tendon differentiation in the Irxl1 knockout mice (2011) (0)
- Report on Review of Appeal of STAP Cell Research Paper Investigation Results (2014) (0)
- Role of the polycomb gene BCOR in hematopoiesis (2014) (0)
- Analysis of Recql4 helicase deficient mice (2003) (0)
- P54. RYBP function in ES cells (2010) (0)
- DJ-1 depletion slows down immunoaging in T-cell compartments (2021) (0)
- Inhibition of immunoglobulin class-switching prevents pemphigus onset in desmoglein 3-specific B cell receptor knock-in mouse (2021) (0)
- Biological and genetic characterization of the role of SRSF2 mutations in the pathogenesis of myelodysplastic syndromes (2015) (0)
- Apoptosis of Effector Th2 Cells in the Lung through the Inhibition of Bim-Mediated Regulates Th2-Driven Airway Inflammation Group Gene Product Ring1B Polycomb (2010) (0)
- Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation (2015) (0)
- sample information of the human samples (2017) (0)
- Application of iPS technology for NKT cell-mediated tumor immunotherapy. (2015) (0)
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What Schools Are Affiliated With Haruhiko Koseki?
Haruhiko Koseki is affiliated with the following schools: